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Desquamation

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81. Overview of dermatitis

by overexposure to ultraviolet (UV) radiation. Skin findings include erythema and oedema, with or without vesiculation, followed by desquamation. Symptoms include pain and/or pruritus. Acute sunburn is a self-limited condition and typically requires only supportive care. No current treatments can reverse UV-induced skin damage. Han A, Maibach, HI. Management of acute sunburn. Am J Clin Dermatol. 2004;5(1):39-47. http://www.ncbi.nlm.nih.gov/pubmed/14979742?tool=bestpractice.com Primary prevention via sun

2018 BMJ Best Practice

82. Overview of skin cancer

to wear broad-spectrum sunscreen regardless of treatment. Sunburn is an acute inflammatory reaction of the skin induced by overexposure to UV radiation. Skin findings include erythema and oedema, with or without vesiculation, followed by desquamation. Symptoms include pain and/or pruritus. Acute sunburn is a self-limiting condition and typically requires only supportive care. Primary prevention via sun avoidance, physical protection, and the appropriate use of sunscreen is key to managing

2018 BMJ Best Practice

83. Kawasaki disease

Kawasaki disease Kawasaki disease - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Kawasaki disease Last reviewed: February 2019 Last updated: March 2018 Summary Acute febrile illness lasting 5 or more days. Typical signs include fever, polymorphic rash, injected eyes, and mucosal erythema with strawberry tongue. Swelling and erythema of the hands and feet occur in the acute stage, followed by desquamation

2018 BMJ Best Practice

84. Overview of dermatitis

by overexposure to ultraviolet (UV) radiation. Skin findings include erythema and oedema, with or without vesiculation, followed by desquamation. Symptoms include pain and/or pruritus. Acute sunburn is a self-limited condition and typically requires only supportive care. No current treatments can reverse UV-induced skin damage. Han A, Maibach, HI. Management of acute sunburn. Am J Clin Dermatol. 2004;5(1):39-47. http://www.ncbi.nlm.nih.gov/pubmed/14979742?tool=bestpractice.com Primary prevention via sun

2018 BMJ Best Practice

86. Peramivir (Alpivab) - Influenza, Human

inflammation and oedema of the larynx, trachea, and bronchi; mucosal biopsies show lymphocytic and histiocytic inflammatory infiltrate and desquamation (Walsh et al., 1961). The viral neuraminidase cleaves sialic acid groups from glycoproteins and facilitates viral escape from infected cells, making it possible for daughter virions to infect new host cells. 2.1.4. Clinical presentation, diagnosis and stage/prognosis Typical influenza illness is characterised by abrupt onset of fever, headache, myalgia

2018 European Medicines Agency - EPARs

90. Radiation Therapy for the Whole-Breast (ASTRO)

be as homogeneous as possible. Several investigators have found less desquamation when the maximum dose is minimized to 105% or 107% of the prescription dose. 44,67,68 Although no dosimetric constraint regarding dose homogeneity has been widely embraced, one might consider a constraint such as no more than 200cc >105% and 2cc >107%, which was endorsed by the experts on the task force as a reasonable goal for most cases. Additional research is needed to establish optimal benchmarks for dose homogeneity

2019 American Society for Radiation Oncology

92. British Association of Dermatologists and U.K. Curaneous Lymphoma Group (CLG) guidelines for the management of primary cutaneous lymphomas

30 Gy to the whole skin deliv- ering 15-Gy fractions per 1-day cycle over 5 weeks. 117 TSEB delivering 30–36 Gy is associated with signi?cant toxicity in some patients. Fatigue has been reported in 38% of patients, erythema and desquamation in 47–76%, alopecia in 95%, lower-leg oedema in 26%, blisters in 19–52% and skin infec- tion in 31–32%. 117,120 A recent review has shown similar response rates and dura- tion of response with lower doses of TSEB (10–30 Gy), 121 but a lower median response

2019 British Association of Dermatologists

93. Topical Photodynamic therapy

compared with ingenol mebutate in the treatment of 27 patients with 323 grade I and II AK with identical response rate. 83 Combination therapy using DL PDT A case series of 11 subjects with grade I-III AKs evaluated with a split-face design the effect of once-daily calcipotriol ointment for 15 days prior to DL MAL-PDT compared with PDT alone. After 3 months, the complete response rate was 85% and 70% although the combination was associated to more erythema and desquamation. 84 A randomized controlled

2019 European Dermatology Forum

94. Clinical Practice Guidelines – Thyroid cancer

(NCT02973997). AEsofMKIs: AEs occurred in 98.6% of patients receiving sora- fenib during the DECISION trial [96]: hand–foot syndrome, diarrhoea, alopaecia, rash or desquamation, fatigue, weight loss and hypertension were the most common. Serum TSH levels exceeding 0.5 mIU/ml were observed in 33.3% patients (69/207) in the sorafenib arm. TSH increases are a recognised AE of sorafe- nib and other MKIs, and levels should be checked monthly to en- sure that suppression is maintained. Serious AEs were

2020 European Society for Medical Oncology

95. Lichen Planus

are well described in an article of the British Society of Oral Medicine. 39 The criteria for diagnosis of genital mucosal LP were recently clearly established. 40 1. In the oral cavity LP may be plaque-like or erosive. Oral reticulated lesions are common on the gingival, buccal mucosa and the tongue. This is the most common manifestation, presenting as a lacy network of white striations. Erosive lesions may also present with desquamative gingivitis or ulceration particularly along the lateral border

2018 European Dermatology Forum

97. CRACKCast E141 – Heat Illness

inflammatory skin disorder: the blockage of sweat gland pores by macerated stratum corneum and secondary staphylococcal infection. intensely pruritic vesicles on an erythematous base. The rash is confined to clothed areas. Rash can persist for weeks Chlorhexidine in a light cream or lotion is the antibacterial treatment of choice during the acute phase. Salicylic acid, 1% tid, can be applied to localized affected areas to assist in desquamation, Prickly heat can be prevented by wearing light, loose fitting

2018 CandiEM

98. Optimal Use of Ionizing Radiation in Cardiovascular Imaging

?uoroscopyandx-rayCThaveaof photon energy spectrum between 30 and 140 keV (the energy spectrum of x-rays generated in typical diagnostic x-ray tubes includes photon energies 40 weeks) 0–2 No observable effects 2–5 Transient erythema Possible epilation Recovery of hair loss Complete healing 5–10 Transient erythema Erythema epilation Recovery or permanent hair loss At higher doses dermal atrophy or induration 10–15 Transient erythema Epilation, possible desquamation Prolonged erythema, permanent hair loss (...) Dermal atrophy or induration >15 Transient erythema, after very high doses ulceration Epilation, moist desquamation Dermal atrophy, secondary ulceration, necrosis Dermal atrophy, possible late skin breakdown, ulceration, and necrosis of subcutaneous tissues Adapted from Balter et al. (17). Hirshfeld et al. JACC VOL. -,NO. -,2018 ECD on Optimal Use of Ionizing Radiation in CV Imaging -,2018:-–- e16Whetherornotprolongedlow-levelradiationexposure (such as occurs in occupational exposures) has

2018 American College of Cardiology

100. CRACKCast E169 – Paediatric Respiratory Emergencies: Lower Airway Obstruction

patient, viral replication often begins in the epithelial cells of the upper airway before spreading to the mucosal surfaces of the lower respiratory tract. The infected epithelial cells are generally destroyed by lysis or apoptosis, which results in the desquamation of these cells and release of host inflammatory mediators. Affected lungs demonstrate epithelial cell necrosis, monocytic inflammation and edema of the peribronchial tissues, and mucus and fibrin plugging of the distal airways

2018 CandiEM

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