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Dermatitis Herpetiformis

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41. Dermatitis herpetiformis: clinical presentations are independent of manifestations of celiac disease. (PubMed)

Dermatitis herpetiformis: clinical presentations are independent of manifestations of celiac disease. Dermatitis herpetiformis (DH) is a skin manifestation of celiac disease (CD), and is often the presenting and only complaint. There are few data comparing those with DH who present only with DH and those with DH who present mainly due to CD.We compared the prevalence of features usually associated with CD in those who presented with DH with patients in whom DH was part of a typical CD

2014 American journal of clinical dermatology

42. Evidence for a role of autoantibodies to heat shock protein 60, 70, and 90 in patients with dermatitis herpetiformis (PubMed)

Evidence for a role of autoantibodies to heat shock protein 60, 70, and 90 in patients with dermatitis herpetiformis Heat shock proteins (Hsp) are highly conserved immunomodulatory molecules upregulated when cells are exposed to stressful stimuli, such as inflammation. Their involvement in various autoimmune diseases, including autoimmune bullous diseases and celiac disease, has been increasingly recognized. To further study the role of Hsp in autoimmune bullous diseases, we have investigated (...) for the first time the humoral autoimmune response to Hsp40, Hsp60, Hsp70, and Hsp90 in patients with dermatitis herpetiformis (DH; n = 26), bullous pemphigoid (BP; n = 23), and pemphigus vulgaris (PV; n = 16), the first representing a cutaneous manifestation of celiac disease. While in patients with active BP and PV, serum levels of autoantibodies against these Hsp did not differ from the corresponding age- and gender-matched healthy controls (n = 9-14); circulating autoantibodies against Hsp60, Hsp70

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2014 Cell stress & chaperones

43. Dermatitis Herpetiformis (Diagnosis)

Dermatitis Herpetiformis (Diagnosis) Dermatitis Herpetiformis: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2MjY0MC1vdmVydmlldw== processing > Dermatitis Herpetiformis (...) Updated: Jun 06, 2018 Author: Jami L Miller, MD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Dermatitis Herpetiformis Overview Background Dermatitis herpetiformis is an exquisitely pruritic eruption classically seen on the buttocks and the extensor surfaces of the arms and legs. Severe cases may involve larger surface areas. Dermatitis herpetiformis is an autoimmune blistering disorder that is often associated with a (GSE). The disease was described and named

2014 eMedicine.com

44. Dermatitis Herpetiformis (Overview)

Dermatitis Herpetiformis (Overview) Dermatitis Herpetiformis: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2MjY0MC1vdmVydmlldw== processing > Dermatitis Herpetiformis (...) Updated: Jun 06, 2018 Author: Jami L Miller, MD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Dermatitis Herpetiformis Overview Background Dermatitis herpetiformis is an exquisitely pruritic eruption classically seen on the buttocks and the extensor surfaces of the arms and legs. Severe cases may involve larger surface areas. Dermatitis herpetiformis is an autoimmune blistering disorder that is often associated with a (GSE). The disease was described and named

2014 eMedicine.com

45. Dermatitis Herpetiformis (Treatment)

Dermatitis Herpetiformis (Treatment) Dermatitis Herpetiformis Treatment & Management: Medical Care, Consultations, Diet Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2MjY0MC10cmVhdG1lbnQ= processing (...) > Dermatitis Herpetiformis Treatment & Management Updated: Jun 06, 2018 Author: Jami L Miller, MD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Dermatitis Herpetiformis Treatment Medical Care Treatment of dermatitis herpetiformis (DH) include avoidance of gluten by consuming a gluten-free diet and pharmacotherapy. [ ] A gluten-free diet is a lifelong commitment, and adherence to a strict diet is difficult to achieve. Improvement of skin disease with a gluten free diet

2014 eMedicine.com

46. Dermatitis Herpetiformis (Follow-up)

Dermatitis Herpetiformis (Follow-up) Dermatitis Herpetiformis Treatment & Management: Medical Care, Consultations, Diet Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2MjY0MC10cmVhdG1lbnQ= processing (...) > Dermatitis Herpetiformis Treatment & Management Updated: Jun 06, 2018 Author: Jami L Miller, MD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Dermatitis Herpetiformis Treatment Medical Care Treatment of dermatitis herpetiformis (DH) include avoidance of gluten by consuming a gluten-free diet and pharmacotherapy. [ ] A gluten-free diet is a lifelong commitment, and adherence to a strict diet is difficult to achieve. Improvement of skin disease with a gluten free diet

2014 eMedicine.com

47. Impetigo Herpetiformis Complicated with Intrauterine Growth Restriction Treated Successfully with Granulocyte and Monocyte Apheresis. (PubMed)

Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu , 807-8555, Japan. natsuko-saito@med.uoeh-u.ac.jp. Izu Kunio K Sawada Yu Y Hino Ryosuke R Nakano Ryoji R Shimajiri Shohei S Nishimura Izumi I Nakamura Hiromasa H Sugiura Kazumitsu K Nakamura Motonobu M eng Case Reports Journal Article Sweden Acta Derm Venereol 0370310 0001-5555 IM Biopsy Dermatitis Herpetiformis blood diagnosis therapy Female Fetal Growth Retardation blood diagnosis immunology therapy Granulocytes immunology Humans Impetigo blood (...) Impetigo Herpetiformis Complicated with Intrauterine Growth Restriction Treated Successfully with Granulocyte and Monocyte Apheresis. 27573023 2017 03 20 2017 05 05 1651-2057 97 3 2017 03 10 Acta dermato-venereologica Acta Derm. Venereol. Impetigo Herpetiformis Complicated with Intrauterine Growth Restriction Treated Successfully with Granulocyte and Monocyte Apheresis. 410-411 10.2340/00015555-2527 Saito-Sasaki Natsuko N Department of Dermatology, University of Occupational and Environmental

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2016 Acta Dermato-Venereologica

48. Small Bowel Transglutaminase 2-specific IgA Deposits in Dermatitis Herpetiformis. (PubMed)

Small Bowel Transglutaminase 2-specific IgA Deposits in Dermatitis Herpetiformis. Dermatitis herpetiformis (DH) is an extraintestinal manifestation of coeliac disease. Untreated coeliac disease patients are known to have transglutaminase 2 (TG2)-targeted IgA deposits in the small bowel mucosa. To evaluate whether similar intestinal IgA deposits are also present in DH and whether the deposits disappear with gluten-free diet, 47 untreated and 27 treated DH patients were studied. Seventy-nine

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2013 Acta Dermato-Venereologica

49. Acral Purpura as Leading Clinical Manifestation of Dermatitis Herpetiformis: Report of Two Adult Cases with a Review of the Literature. (PubMed)

Acral Purpura as Leading Clinical Manifestation of Dermatitis Herpetiformis: Report of Two Adult Cases with a Review of the Literature. Dermatitis herpetiformis (DH) is an autoimmune disease that clinically manifests as pruritic vesicles and papules. The diagnosis of DH is often challenging because of its wide spectrum of clinical presentations. We here report 2 patients with DH in whom finger petechiae represented the initial and leading manifestation of the disease, and the confirmed

2013 Dermatology

50. Concomitant Bullous Pemphigoid and Dermatitis Herpetiformis. (PubMed)

Concomitant Bullous Pemphigoid and Dermatitis Herpetiformis. Dermatitis herpetiformis and bullous pemphigoid are bullous autoimmune diseases of the skin microscopically characterized by subepidermal blisters. We present a 77-year-old patient with an 18-month history of disseminated pruritic papular lesions. Direct immunofluorescence microscopy revealed linear deposition of IgG at the basement membrane zone as well as granular deposits of IgA in the papillary dermis. Circulating IgG antibodies (...) against BP180, BP230 and gliadin as well as IgA reactivity against endomysium, tissue transglutaminase, and gliadin were detected compatible with both bullous pemphigoid and dermatitis herpetiformis. Here, we review the English literature on all previously reported patients with co-occurrence of both entities. Interestingly, in previous cases, tissue-bound and serum autoantibodies against the respective target antigens had not yet been completely characterized. Copyright © 2013 S. Karger AG, Basel.

2013 Dermatology

51. Is dermatitis herpetiformis a proxy of prosperity? (PubMed)

Is dermatitis herpetiformis a proxy of prosperity? 23496160 2014 01 29 2018 12 03 1365-2133 169 1 2013 Jul The British journal of dermatology Br. J. Dermatol. Is dermatitis herpetiformis a proxy of prosperity? 231 10.1111/bjd.12319 Ali F R FR Lear J T JT eng Letter Comment England Br J Dermatol 0004041 0007-0963 IM Br J Dermatol. 2012 Dec;167(6):1331-7 22708883 Dermatitis Herpetiformis mortality Female Humans Male 2013 3 19 6 0 2013 3 19 6 0 2014 1 30 6 0 ppublish 23496160 10.1111/bjd.12319

2013 British Journal of Dermatology

52. IgA anti-epidermal transglutaminase autoantibodies: a sensible and sensitive marker for diagnosis of dermatitis herpetiformis in adult patients. (PubMed)

IgA anti-epidermal transglutaminase autoantibodies: a sensible and sensitive marker for diagnosis of dermatitis herpetiformis in adult patients. Dermatitis herpetiformis (DH) is a rare gluten-sensitive blistering itchy skin disease, strictly related to coeliac disease (CD). Direct immunofluorescence, demonstrating IgA granular deposits localized either in the dermal papillae or along the dermo-epidermal junction, is currently the gold standard for diagnosis of DH. It has been shown that DH (...) immunocomplexes contain epidermal transglutaminase (eTG) and that sera from patients with DH contain antibodies specifically directed against eTG.We studied the usefulness of serum eTG antibodies in discriminating between DH, CD and other gastrointestinal and dermatologic diseases.eTG antibodies were tested in 308 adult patients' sera: 44 patients with untreated dermatitis herpetiformis (UDH), 99 patients with untreated coeliac disease (UCD), 70 dermatological controls and 95 gastrointestinal controls.In UDH

2013 Journal of the European Academy of Dermatology and Venereology

53. Psoriasis and Exfoliative Dermatitis lapsing into Dermatitis Herpetiformis (Duhring) (PubMed)

Psoriasis and Exfoliative Dermatitis lapsing into Dermatitis Herpetiformis (Duhring) 19977633 2010 06 24 2010 06 24 0035-9157 7 Dermatol Sect 1914 Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. Psoriasis and Exfoliative Dermatitis lapsing into Dermatitis Herpetiformis (Duhring). 173-5 Semon H C HC eng Journal Article England Proc R Soc Med 7505890 0035-9157 2009 12 9 6 0 1914 1 1 0 0 1914 1 1 0 1 ppublish 19977633 PMC2003843

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1914 Proceedings of the Royal Society of Medicine

54. Letter to the editor: Application of dapsone 5% gel in a patient with dermatitis herpetiformis (PubMed)

Letter to the editor: Application of dapsone 5% gel in a patient with dermatitis herpetiformis 23329996 2013 01 21 2018 11 13 1898-7249 6 4 2012 Dec 31 Journal of dermatological case reports J Dermatol Case Rep Letter to the editor: Application of dapsone 5% gel in a patient with dermatitis herpetiformis. 132-3 10.3315/jdcr.2012.1124 Handler Marc Z MZ University of Miami Miller School of Medicine - Department of Dermatology & Cutaneous Surgery, Miami, FL 33136. Chacon Anna H AH Shiman Michael I

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2012 Journal of dermatological case reports

55. Reduced mortality in dermatitis herpetiformis: a population-based study of 476 patients. (PubMed)

Reduced mortality in dermatitis herpetiformis: a population-based study of 476 patients. Dermatitis herpetiformis (DH) is an extra-intestinal manifestation of coeliac disease and most patients adhere to a life-long gluten free diet (GFD). Increased mortality rates have been reported in coeliac disease but knowledge in DH is scanty.To survey the mortality rate and causes of death in a large cohort of patients with DH.Patients with DH (n = 476 consecutive patients) diagnosed from 1970 onwards

2012 British Journal of Dermatology

56. Dermatitis herpetiformis in China: a report of 22 cases. (PubMed)

Dermatitis herpetiformis in China: a report of 22 cases. Although dermatitis herpetiformis (DH) is a relatively common disease in Caucasian populations, it is very rare in the Far East, including China.To investigate the clinical, histological and immunopathological characteristics of Chinese patients with DH.The clinical data and serum samples of patients with DH diagnosed at Shandong Provincial Institute of Dermatology and Venereology from 2006 to 2010 were collected. Anti-endomysium

2012 Journal of the European Academy of Dermatology and Venereology

57. Association between Levels of IgA Antibodies to Tissue Transglutaminase and Gliadin-Related Nonapeptides in Dermatitis Herpetiformis (PubMed)

Association between Levels of IgA Antibodies to Tissue Transglutaminase and Gliadin-Related Nonapeptides in Dermatitis Herpetiformis Dermatitis herpetiformis (DH) is an autoimmunity-driven inflammatory blistering dermatosis associated with a gluten-dependent enteropathy. Tissue transglutaminase (tTG) and nonapeptides of gliadin (npG) are considered in its pathomechanism/diagnostics. Here, the diagnostic accuracy of anti-tTG/anti-npG IgA ELISAs in Slavic DH patients with active skin rash

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2012 The Scientific World Journal

58. Newly Described Clinical and Immunopathological Feature of Dermatitis Herpetiformis (PubMed)

Newly Described Clinical and Immunopathological Feature of Dermatitis Herpetiformis Dermatitis herpetiformis (DH) is an inflammatory cutaneous disease with typical histopathological and immunopathological findings clinically characterized by intensely pruritic polymorphic lesions with a chronic-relapsing course. In addition to classic clinical manifestations of DH, atypical variants are more and more frequently reported and histological and immunological are added to them, whereas the impact

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2012 Clinical and Developmental Immunology

59. The Expression of Selected Proapoptotic Molecules in Dermatitis Herpetiformis (PubMed)

The Expression of Selected Proapoptotic Molecules in Dermatitis Herpetiformis The role of the process of apoptosis is investigated in the pathogenesis of many autoimmune diseases; however at present, there is not much information about its role in dermatitis herpetiformis. Skin biopsies were taken from 18 DH patients and from 10 healthy subjects. The localization and expression of Bax, Fas, FasL, TRAIL, TRAIL-R in skin lesions, and perilesional skin were studied by immunohistochemistry (...) in Fas, FasL, and TRAIL expression. There were statistically significant differences between control group and perilesional skin in Bax and FasL expression. Our results show that selected proapoptotic molecules may take part in pathogenesis of dermatitis herpetiformis, but the role of apoptosis in this process is not clear.

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2012 Clinical and Developmental Immunology

60. Novel Therapeutic/Integrative Approaches for Celiac Disease and Dermatitis Herpetiformis (PubMed)

Novel Therapeutic/Integrative Approaches for Celiac Disease and Dermatitis Herpetiformis Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. Gluten is a protein component in wheat and other cereals like rye and barley. At present, the only available treatment is a strict gluten-free diet. Recent advances have increased our understanding of the molecular basis for this disorder. Last decade has seen new scientific

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2012 Clinical and Developmental Immunology

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