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Dermal Filler Injection

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81. Study for the Evaluation of the Efficacy and Safety of the Dermal Filler Princess® VOLUME in Nasolabial Folds

Study for the Evaluation of the Efficacy and Safety of the Dermal Filler Princess® VOLUME in Nasolabial Folds Study for the Evaluation of the Efficacy and Safety of the Dermal Filler Princess® VOLUME in Nasolabial Folds - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. Study for the Evaluation of the Efficacy and Safety of the Dermal Filler Princess® VOLUME in Nasolabial Folds The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01798498 Recruitment Status : Completed First Posted : February 26, 2013

2013 Clinical Trials

82. Perils of dermal fillers. Full Text available with Trip Pro

Perils of dermal fillers. With the increasing use of hyaluronic acid-based injectable fillers for cosmetic enhancement a variety of adverse reactions are being reported in the literature. Although most adverse outcomes occur early we describe an interesting case study of a female presenting with granulomatous complications ten years postoperatively. To our knowledge this is one of the longest reported delayed reactions. For the general dental practitioner offering such treatments

2013 British Dental Journal

83. Early granulomatous foreign body reactions to a novel alginate dermal filler: the system's failure? (Abstract)

Early granulomatous foreign body reactions to a novel alginate dermal filler: the system's failure? Cutaneous granulomas after a soft filler injection represent one of the worst scenarios for both patient and injector.To present clinical and histopathological features of granulomatous nodular reactions induced by a new alginate-based dermal filler (Novabel(®)), and put it in context of the process of injectable soft tissue fillers approval and promotion in the EU.A case series of four patients (...) injected with Novabel(®) for volume restoration of the face and hands, who developed severe foreign body reactions.Four patients injected with Novabel(®) into tear troughs and/or dorsa of hands developed severe granulomatous reactions within months after injections. As we injected with the new filler into a total of 10 patients, a high incidence of 40% of the disfiguring adverse effect was observed. The inadequate response of manufacturer to our reporting the side-effects along with the available data

2013 Journal of the European Academy of Dermatology and Venereology

84. Dermal filler complications from unknown biomaterials: identification by attenuated total reflectance spectroscopy. (Abstract)

Dermal filler complications from unknown biomaterials: identification by attenuated total reflectance spectroscopy. In the last decade, an increase in complications related to dermal filler injections has been reported, especially in patients who underwent multiple treatments with different products. Imaging or histological examinations may suggest what kind of substance was used, but none can precisely identify the biomaterial. The aim of this study was to evaluate the use of Fourier transform (...) complications due to multiple injections with unknown fillers provided a sample of the pathological tissue for the analysis.Two granulomas, two infiltrated tissues, and three abscesses were studied. Attenuated total reflectance/Fourier transform infrared analysis of pathological tissues revealed the presence of absorption bands absent in the healthy tissue. Comparison of these bands to the filler database made it possible to identify the dermal fillers injected.This pilot study has demonstrated the absolute

2013 Plastic and reconstructive surgery

85. Inflammatory, immune-mediated adverse reactions related to soft tissue dermal fillers. (Abstract)

related to medical dermal filler injections/prosthesis.A comprehensive MEDLINE, PubMed, and Google Scholar electronic database search was performed (2000-January 2012). Selected articles published before 2000 referring to general concerns regarding the studied topic were also included. The search provided almost 300 articles. Finally, 235 studies were selected and included.All known fillers present in the market have been shown to be able to provoke early- and late-onset inflammatory adverse reactions (...) Inflammatory, immune-mediated adverse reactions related to soft tissue dermal fillers. An increasing number of persons seek medical solutions for esthetic indications and for diverse pathological conditions, such as malformations, trauma, or cancer. Despite manufacturers' and different authors' claims that fillers are non-immunogenic or that complications are uncommon, unwanted adverse reactions do occur.To review the literature regarding the multiple types of immune-mediated adverse reactions

2013 Seminars in arthritis and rheumatism

86. Association between collagen production and mechanical stretching in dermal extracellular matrix: In vivo effect of cross-linked hyaluronic acid filler. A randomised, placebo-controlled study. (Abstract)

Association between collagen production and mechanical stretching in dermal extracellular matrix: In vivo effect of cross-linked hyaluronic acid filler. A randomised, placebo-controlled study. The effects of hyaluronic acid (HA) injection on tissue collagen anabolism are suggested to be related to the induction of mechanical stress, causing biochemical changes in skin physiology.To ascertain the association between dermal mechanics modulated by a hyaluronic acid-based filler effect (...) digital modelling.One month after injection, the filler induced an increase in procollagen (p=0.0016) and TIMP-1 (p=0.0485) levels and relative gene expression of procollagen III and I isoforms compared with the controls. After 3 months, procollagen levels remained greater than in the controls (p=0.0005), whereas procollagen expression and TIMP-1 and MMP content were no longer different. Forty-three percent of the injected filler volume was found at 1 month, 26% after 3 months and 20% after 6

2013 Journal of dermatological science Controlled trial quality: uncertain

87. Permanent and semi permanent dermal fillers

with temporary products in those studies that compared them, and that aesthetic improvements are maintained over time. Case series evidence suggests that permanent and semi-permanent dermal fillers achieve their objective, which is to decrease the visible (objective or subjective) effects of age related changes or HIV-associated facial lipoatrophy with high patient satisfaction. Although the most common adverse events were mild and appeared to be related to the act of injection, palpable lumps were present (...) Permanent and semi permanent dermal fillers Permanent and semi permanent dermal fillers Permanent and semi permanent dermal fillers Sturm L Record Status This is a bibliographic record of an ongoing health technology assessment being undertaken by a member of INAHTA. Links to the published report and any other relevant documentation will be added when available. Citation Sturm L. Permanent and semi permanent dermal fillers. Stepney: Australian Safety and Efficacy Register of New Interventional

2009 Health Technology Assessment (HTA) Database.

88. Polymethylmethacrylate dermal fillers: evaluation of the systemic toxicity in rats. (Abstract)

Polymethylmethacrylate dermal fillers: evaluation of the systemic toxicity in rats. This study evaluated local and systemic reactions after an intravascular injection of polymethylmethacrylate (PMMA) at two concentrations in a murine model. Thirty rats were divided equally into three groups: 2% PMMA, 30% PMMA, and a control group (normal saline only injection). The filler was injected into the ranine vein. The rats were sedated at 7 and 90 days and a clinical evaluation performed. After (...) presented higher levels of alanine aminotransferase (P = 0.047) after 90 days when compared with the other groups. The data obtained in this study demonstrate that intravascular injections of PMMA fillers show potential health risks such as chronic inflammation at the implantation site.Copyright © 2013 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

2013 International Journal of Oral and Maxillofacial Surgery

89. Lower Face Rejuvenation with Injections: Botox, Juvederm, and Kybella for Marionette Lines and Jowls Full Text available with Trip Pro

plastic surgeons (none of whom were the author of this study) based on the WAS scale and before and after photographs to evaluate the corners of the mouth and the marionette lines. This case study report suggests that the combined use of neuromodulator, hyaluronic acid dermal filler, and synthetic deoxycholic acid can rejuvenate the lower face as a minimally invasive alternative to surgery to the satisfaction of the patient and 6 plastic surgeons (including the author). (...) Lower Face Rejuvenation with Injections: Botox, Juvederm, and Kybella for Marionette Lines and Jowls A 55-year-old woman requesting noninvasive rejuvenation of the lower face received multimodal injections in a single office visit to rejuvenate the jowls. The patient experienced no adverse events other than self-limiting bruising at the hyaluronic acid injection site and minimal edema. The outcomes were evaluated as follows: (1) by the patient using the self-rated Face-Q assessment and (2) by 5

2017 Plastic and Reconstructive Surgery Global Open

90. Injections through skin colonized with Staphylococcus aureus biofilm introduce contamination despite standard antimicrobial preparation procedures Full Text available with Trip Pro

, aspiration biopsies and dermal fillers (DF). In this work, we develop two in vitro models to simulate the process of skin preparation and DF injection using pig skin and SimSkin (silicone) materials, respectively. Using the pig skin model, we tested three of the most common skin preparation wipes (alcohol, chlorhexidine and povidone iodine) and found that during wiping they reduced the biofilm bacterial burden of S. aureus (CFU cm-2) by three logs with no statistically significant differences between (...) Injections through skin colonized with Staphylococcus aureus biofilm introduce contamination despite standard antimicrobial preparation procedures While surgical site preparation has been extensively studied, there is little information about resistance of skin microbiota in the biofilm form to antimicrobial decontamination, and there are no quantitative models to study how biofilm might be transferred into sterile tissue/implant materials during injections for joint spine and tendon

2017 Scientific reports

91. Face Photoaging: Efficacy and Tolerance Evaluation of an Intradermal Injective Treatment

) variation (± 1) during the study period; subjects not in menopause who do not accept to perform the pregnancy test during the basal visit, 30 days (T4i) and 2 months (T2M) after the first biomineralizing treatment execution; performing skin treatments for aesthetic correction (biomaterials implants, face lifting, botox injections, laser, chemical peeling) in the 12 months prior to the study start; performing permanent filler in the past; change in the normal habits regarding food, physical activity (...) Face Photoaging: Efficacy and Tolerance Evaluation of an Intradermal Injective Treatment Face Photoaging: Efficacy and Tolerance Evaluation of an Intradermal Injective Treatment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies

2017 Clinical Trials

92. Safety and Effectiveness of JUVÉDERM VOLUMA® XC Injectable Gel for Correction of Temple Hollowing

. Exclusion Criteria: Has temple hollowing due to due to trauma, congenital malformations, or lipodystrophy Has received permanent facial implants in the face or neck Has undergone fat injections Has tattoos, piercings, facial hair or scars that would interfere with visual assessment of the temple Has undergone semipermanent dermal filler treatment in the temple or mid-face within the past 36 months Has undergone dermal filler injections above the subnasale within the past 24 months Has temporal arteritis (...) Safety and Effectiveness of JUVÉDERM VOLUMA® XC Injectable Gel for Correction of Temple Hollowing Safety and Effectiveness of JUVÉDERM VOLUMA® XC Injectable Gel for Correction of Temple Hollowing - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove

2017 Clinical Trials

93. Safety and Effectiveness of Juvéderm Ultra Plus Injectable Gel in Correcting Severe Nasolabial Folds in Chinese Subjects. Full Text available with Trip Pro

Safety and Effectiveness of Juvéderm Ultra Plus Injectable Gel in Correcting Severe Nasolabial Folds in Chinese Subjects. Hyaluronic acid dermal fillers are effective in correcting severe nasolabial folds (NLFs) in non-Asian populations. We assessed safety and effectiveness of Juvéderm Ultra Plus in a Chinese population.This double-blind study randomized Chinese subjects with severe NLFs to Juvéderm Ultra Plus (24 mg/mL) in 1 NLF and Restylane injectable gel (20 mg/mL) in the other NLF. NLFs

2017 Plastic and reconstructive surgery. Global open Controlled trial quality: uncertain

94. Treatment of the Ageing Hand with Dermal Fillers Full Text available with Trip Pro

with a number of long-lasting dermal fillers with varying degrees of improvement and treatment longevity. The dermal fillers used in hand rejuvenation include autologous fat, collagen, hyaluronic acid, calcium hydroxylapatite and poly-L-lactic acid. Here, we describe our preferred injection method for hand rejuvenation using calcium hydroxylapatite and a single-bolus injection. (...) Treatment of the Ageing Hand with Dermal Fillers Following the trend in facial cosmetic procedures, patients are now increasingly requesting hand rejuvenation treatments. Intrinsic ageing of the hands is characterized by loss of dermal elasticity and atrophy of the subcutaneous tissue. Thus, veins, tendons and bony structures become apparent. Among the available procedures, intrinsic ageing of the hands is best improved by restoring the volume of soft tissue. Volume restoration can be achieved

2012 Journal of cutaneous and aesthetic surgery

95. A prospective, split-face, randomized, comparative study of safety and 12-month longevity of three formulations of hyaluronic acid dermal filler for treatment of nasolabial folds. (Abstract)

A prospective, split-face, randomized, comparative study of safety and 12-month longevity of three formulations of hyaluronic acid dermal filler for treatment of nasolabial folds. Data regarding several hyaluronic acids (HAs) used identically for facial tissue augmentation have heretofore been unavailable.This prospective, split-face, randomized, two-armed study sought to determine the long-term safety and effectiveness of three HAs (HA-1 (Belotero Basic/Balance), HA-2 (Restylane), and HA-3 (...) (Juvéderm Ultra 3/Juvéderm Ultra Plus XC) in the treatment of nasolabial folds (NLFs).Twenty participants in Arm A received HA-1 in one NLF and HA-2 in the other. In Arm B, 20 participants received HA-1 in one NLF and HA-3 in the other. Injection was at visit 2, with follow-up visits at 1, 6, 9, and 12 months. Mean volume of HA was slightly <1.5 mL/NLF.Adverse events were unremarkable across all HAs, with injection site erythema being the most frequent adverse event. Mean pretreatment NLF severity

2012 Dermatologic Surgery Controlled trial quality: uncertain

96. Permanent and semi-permanent dermal fillers: A systematic review

The skin 1 The ageing process 1 HIV-associated lipodystrophy syndrome 1 Non-surgical therapies for facial augmentation 3 Topical therapies 3 Injectable agents 3 Dermal fillers 4 Types of dermal fillers 4 Temporary fillers 5 Semi-permanent fillers 5 Permanent fillers 5 How dermal fillers work 9 Demand for cosmetic procedures 10 Australian cosmetic industry 10 Summary 11 2. Methodology 12 Literature search protocol 12 Inclusion criteria 12 Literature search strategies 14 Databases searched and search (...) References 91 Appendix A – Excluded studies 101 Appendix B – Study profile tables 104 Appendix C – Treatment data 128 - ASERNIP-S REVIEW OF PERMANENT AND SEMI-PERMANENT DERMAL FILLERS. FEBRUARY 2009 - iv List of Tables Table 1. Classification of dermal fillers by composition 5 Table 2. Classification of injectable semi-permanent and permanent dermal fillers 6 Table 3. Databases searched 14 Table 4. NHMRC hierarchy of evidence 16 Table 5. Summary of included studies 19 Table 6. Dermal fillers for ageing

2009 Publication 80

97. Permanent and semi-permanent dermal fillers: a systematic review

The skin 1 The ageing process 1 HIV-associated lipodystrophy syndrome 1 Non-surgical therapies for facial augmentation 3 Topical therapies 3 Injectable agents 3 Dermal fillers 4 Types of dermal fillers 4 Temporary fillers 5 Semi-permanent fillers 5 Permanent fillers 5 How dermal fillers work 9 Demand for cosmetic procedures 10 Australian cosmetic industry 10 Summary 11 2. Methodology 12 Literature search protocol 12 Inclusion criteria 12 Literature search strategies 14 Databases searched and search (...) References 91 Appendix A – Excluded studies 101 Appendix B – Study profile tables 104 Appendix C – Treatment data 128 - ASERNIP-S REVIEW OF PERMANENT AND SEMI-PERMANENT DERMAL FILLERS. FEBRUARY 2009 - iv List of Tables Table 1. Classification of dermal fillers by composition 5 Table 2. Classification of injectable semi-permanent and permanent dermal fillers 6 Table 3. Databases searched 14 Table 4. NHMRC hierarchy of evidence 16 Table 5. Summary of included studies 19 Table 6. Dermal fillers for ageing

2009 Publication 80

98. The Use of J-Plasma® for Dermal Resurfacing

is willing to release rights to study Sponsor for the use of the photos, including in potential publication. Subject is willing to abstain from other facial cosmetic procedures through the 6 month follow-up visit; examples include, but are not limited to, laser or chemical re-surfacing, dermabrasion, neuromodulator and/or filler injections, aesthetic facial surgery, etc. Exclusion Criteria: Subject with a Fitzpatrick Skin Scale score >III. Subject is pregnant or lactating. Active HSV-1 or diabetes (...) The Use of J-Plasma® for Dermal Resurfacing The Use of J-Plasma® for Dermal Resurfacing - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. The Use of J-Plasma® for Dermal Resurfacing The safety and scientific

2017 Clinical Trials

99. Injection Assistance Device Versus Manual Injections for Delivery of Dermal Fillers

Injection Assistance Device Versus Manual Injections for Delivery of Dermal Fillers Injection Assistance Device Versus Manual Injections for Delivery of Dermal Fillers - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Injection Assistance Device Versus Manual Injections for Delivery of Dermal Fillers The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01492140 Recruitment Status : Unknown Verified December 2011 by TKL Research, Inc.. Recruitment status was: Active, not recruiting First Posted : December 14

2011 Clinical Trials

100. A Randomized Clinical Trial to Evaluate the Efficacy and Safety of Lidocaine-Containing Monophasic Hyaluronic Acid Filler for Nasolabial Folds. (Abstract)

A Randomized Clinical Trial to Evaluate the Efficacy and Safety of Lidocaine-Containing Monophasic Hyaluronic Acid Filler for Nasolabial Folds. Hyaluronic acid dermal fillers are most frequently used for unwanted wrinkles. Recently, lidocaine has been incorporated into hyaluronic acid fillers to reduce injection discomfort.A randomized, multicenter, double-blind, intraindividual trial was designed to compare a new lidocaine-containing monophasic hyaluronic acid filler (Neuramis Deep Lidocaine (...) ) with a lidocaine-containing biphasic hyaluronic acid filler (Restylane Perlane-L) in moderate to severe nasolabial folds. Fifty-eight patients with moderate to severe nasolabial folds were randomized to an injection of Neuramis or Perlane-L in the left or right side of the face. Clinical efficacy and safety were assessed by blinded investigators, independent expert panels, and patients based on the Wrinkle Severity Rating Scale and the Global Aesthetic Improvement Scale at weeks 8, 16, and 24 after

2016 Plastic and reconstructive surgery Controlled trial quality: uncertain

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