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Dermal Filler Injection

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61. Dermal Fillers (Diagnosis)

Updated: Apr 02, 2018 Author: Robert S Bader, MD; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Dermal Fillers Overview Overview Perhaps nothing is more gratifying for cosmetic patients than having an immediate correction of rhytides or scars as a result of the injection of a dermal filler. Before and after photos of patients who have had injection of dermal fillers are shown below. Patient 1. Before photo. Left cheek. Patient 1. After photo. Left cheek. Patient (...) of deeper rhytides and folds, the full potential for dermal fillers was not seen until the recent addition of newer dermal fillers to the armamentarium. The perfect dermal filler would be inexpensive, safe, painless to inject, hypoallergenic, and long lasting. In addition, it should have consistent and predictable results, feel natural under the skin, take little time to inject, be ready-to-use, exert no downtime on the patient, and have a low risk of complications. With the increasing desire for people

2014 eMedicine.com

62. Dermal Fillers (Overview)

Updated: Apr 02, 2018 Author: Robert S Bader, MD; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Dermal Fillers Overview Overview Perhaps nothing is more gratifying for cosmetic patients than having an immediate correction of rhytides or scars as a result of the injection of a dermal filler. Before and after photos of patients who have had injection of dermal fillers are shown below. Patient 1. Before photo. Left cheek. Patient 1. After photo. Left cheek. Patient (...) of deeper rhytides and folds, the full potential for dermal fillers was not seen until the recent addition of newer dermal fillers to the armamentarium. The perfect dermal filler would be inexpensive, safe, painless to inject, hypoallergenic, and long lasting. In addition, it should have consistent and predictable results, feel natural under the skin, take little time to inject, be ready-to-use, exert no downtime on the patient, and have a low risk of complications. With the increasing desire for people

2014 eMedicine.com

63. Dermal Fillers (Treatment)

Updated: Apr 02, 2018 Author: Robert S Bader, MD; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Dermal Fillers Overview Overview Perhaps nothing is more gratifying for cosmetic patients than having an immediate correction of rhytides or scars as a result of the injection of a dermal filler. Before and after photos of patients who have had injection of dermal fillers are shown below. Patient 1. Before photo. Left cheek. Patient 1. After photo. Left cheek. Patient (...) of deeper rhytides and folds, the full potential for dermal fillers was not seen until the recent addition of newer dermal fillers to the armamentarium. The perfect dermal filler would be inexpensive, safe, painless to inject, hypoallergenic, and long lasting. In addition, it should have consistent and predictable results, feel natural under the skin, take little time to inject, be ready-to-use, exert no downtime on the patient, and have a low risk of complications. With the increasing desire for people

2014 eMedicine.com

64. Dermal Fillers (Follow-up)

Updated: Apr 02, 2018 Author: Robert S Bader, MD; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Dermal Fillers Overview Overview Perhaps nothing is more gratifying for cosmetic patients than having an immediate correction of rhytides or scars as a result of the injection of a dermal filler. Before and after photos of patients who have had injection of dermal fillers are shown below. Patient 1. Before photo. Left cheek. Patient 1. After photo. Left cheek. Patient (...) of deeper rhytides and folds, the full potential for dermal fillers was not seen until the recent addition of newer dermal fillers to the armamentarium. The perfect dermal filler would be inexpensive, safe, painless to inject, hypoallergenic, and long lasting. In addition, it should have consistent and predictable results, feel natural under the skin, take little time to inject, be ready-to-use, exert no downtime on the patient, and have a low risk of complications. With the increasing desire for people

2014 eMedicine.com

65. Treatment of Soft Tissue Filler Complications: Expert Consensus Recommendations (Full text)

the management of the complications associated with dermal fillers use. A search was performed for English, French, and Spanish language articles in MEDLINE, the Cochrane Database, and Google Scholar using the search terms "complications" OR "soft filler complications" OR "injectable complications" AND "dermal fillers" AND "Therapy". An initial document was drafted by the Coordinating Committee, and it was reviewed and modified by the experts, until a final text was agreed upon and validated.The panel (...) action protocols for emergencies, with agents readily available in the office, would reduce the severity of adverse outcomes associated with injection of hyaluronic acid fillers in the cosmetic setting. This document seeks to lay down a set of recommendations and to identify key issues that may be useful for clinicians who are starting to use dermal fillers. Additionally, this document provides a better understanding about the diagnoses and management of complications if they do occur.This journal

2018 Aesthetic plastic surgery PubMed

66. Histologic Effects of Fractional Laser and Radiofrequency Devices on Hyaluronic Acid Filler. (PubMed)

were in very close proximity to the filler. The RF devices demonstrated thermal damage of HAF along the microneedle tracks.Hyaluronic acid filler is unaffected by fractional lasers in this model. Fractional RF devices, which produce deeper dermal penetrations, will cause thermal damage of HAF. Caution is advised in using microneedle RF over recently injected filler. Study limitations include use of nonfacial skin and lack of inflammatory response in an ex-vivo model. (...) Histologic Effects of Fractional Laser and Radiofrequency Devices on Hyaluronic Acid Filler. Hyaluronic acid fillers (HAFs) and energy-based devices are frequently used sequentially. However, the effect of using fractional devices directly over HAF is unclear.To evaluate histologic changes after fractional laser and radiofrequency (RF) therapies applied over preinjected HAF.Abdominoplasty skin samples were divided into 8 zones. Intradermal injections of HAF were performed to 7 zones with 1 zone

2018 Dermatologic Surgery

67. Permanent and semi permanent dermal fillers

with temporary products in those studies that compared them, and that aesthetic improvements are maintained over time. Case series evidence suggests that permanent and semi-permanent dermal fillers achieve their objective, which is to decrease the visible (objective or subjective) effects of age related changes or HIV-associated facial lipoatrophy with high patient satisfaction. Although the most common adverse events were mild and appeared to be related to the act of injection, palpable lumps were present (...) Permanent and semi permanent dermal fillers Permanent and semi permanent dermal fillers Permanent and semi permanent dermal fillers Sturm L Record Status This is a bibliographic record of an ongoing health technology assessment being undertaken by a member of INAHTA. Links to the published report and any other relevant documentation will be added when available. Citation Sturm L. Permanent and semi permanent dermal fillers. Stepney: Australian Safety and Efficacy Register of New Interventional

2009 Health Technology Assessment (HTA) Database.

68. Skin Necrosis of the Nasal Ala after Injection of Dermal Fillers. (PubMed)

Skin Necrosis of the Nasal Ala after Injection of Dermal Fillers. 21342316 2011 05 20 2011 03 17 1524-4725 37 3 2011 Mar Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Dermatol Surg Skin necrosis of the nasal ala after injection of dermal fillers. 375-80 10.1111/j.1524-4725.2011.01891.x Kang Moon Seok MS Department of Plastic and Reconstructive Surgery, College of Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Republic of Korea (...) . Park Eun Soo ES Shin Ho Seong HS Jung Sung Gyun SG Kim Yong Bae YB Kim Dong Won DW eng Case Reports Journal Article 2011 02 22 United States Dermatol Surg 9504371 1076-0512 0 Gels 9004-61-9 Hyaluronic Acid IM Adult Female Gels Humans Hyaluronic Acid administration & dosage adverse effects Injections, Intradermal adverse effects Necrosis chemically induced Nose blood supply pathology Nose Deformities, Acquired chemically induced Peripheral Vascular Diseases chemically induced Skin pathology 2011 2

2011 Dermatologic Surgery

69. A randomized comparison of the efficacy of low volume deep placement cheek injection vs. mid- to deep dermal nasolabial fold injection technique for the correction of nasolabial folds. (PubMed)

A randomized comparison of the efficacy of low volume deep placement cheek injection vs. mid- to deep dermal nasolabial fold injection technique for the correction of nasolabial folds. Hyaluronic acid (HA) fillers are FDA approved for improving the appearance of the nasolabial folds. Previous reports on the use of HA for this treatment have focused on injections directly into the location of the desired correction. To our knowledge, a study has not been done evaluating the efficacy of injecting (...) with each technique used with no statistical difference between techniques. Patients showed a slight preference for injection to both the mid- to lateral cheek and nasolabial fold, which was associated with the greatest amount of filler product administered. No serious adverse events were reported.Injection of a dermal filler, at low volumes, into either the nasolabial fold or mid- to lateral cheek results in similar improvement to the correction of the nasolabial folds.© 2014 Wiley Periodicals, Inc.

2014 Journal of cosmetic dermatology

70. Perpendicular Strut Injection of Hyaluronic Acid Filler for Deep Wrinkles (Full text)

Perpendicular Strut Injection of Hyaluronic Acid Filler for Deep Wrinkles Although various injection techniques of hyaluronic acid (HA) filler for facial rejuvenation have been developed, correction of deep wrinkles/grooves, such as the nasolabial fold (NLF), with intradermal or subdermal injections remains difficult. We tested the intradermal HA injection method to place multiple HA struts by (1) inserting a small needle perpendicularly to the wrinkle and (2) injecting HA as intradermal struts (...) with the skin fully stretched by the practitioner's fingers. The results of both NLFs in 10 patients suggest that this technique improves NLFs and maintain the effects more consistently than conventional techniques, although the effects of both methods were almost lost after 6 months. Selective and/or combined application of this technique may enhance the current approach to facial rejuvenation with dermal fillers.

2015 Plastic and Reconstructive Surgery Global Open PubMed

71. Safety and Performance of Princess® FILLER for the Treatment of Facial Lipoatrophy, Asymmetry or Scars

Princess® FILLER injections up to 10 ml applied to the eligible subjects at the baseline visit, and the touch-up visit, if applicable. Outcome Measures Go to Primary Outcome Measures : 6-point scale for clinical response [ Time Frame: Week 4 ] The proportion of patients with successful treatment outcome at the Week 4 visit based on the Investigator's opinion, where success is defined as excellent, good, or moderate correction of the defect Eligibility Criteria Go to Information from the National (...) Inclusion Criteria: Male or female 18 years of age or older. Presence of a defect, which in the opinion of the Investigator can be corrected by a dermal filler, and is caused by: ° Facial lipoatrophy of moderate severity, or Morphological asymmetry of the face, or One or more debilitating scars on the face. Willingness to abstain from any cosmetic or surgical procedures in the treatment area for the duration of the clinical investigation. Willingness to take part in the clinical investigation

2017 Clinical Trials

72. Non-aesthetic indications for periocular hyaluronic acid filler treatment: a review. (PubMed)

Non-aesthetic indications for periocular hyaluronic acid filler treatment: a review. Dermal fillers have been in use for many years for aesthetic rejuvenation of the face. More recently, however, fillers have been increasingly used as an alternative to traditional surgical procedures for non-aesthetic indications. These indications include lagophthalmos, eyelid malpositions and orbital volume deficiency. The advantages of these filler injections are multiple: minimally invasive, repeatable (...) , titratable and even reversible (depending on the product used). We review the current literature of functional uses of filler injections as mentioned above and evaluate the safety profile and efficacy of filler injections for this purpose.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

2017 British Journal of Ophthalmology

73. "Comparing efficacy and costs of four facial fillers in HIV-associated lipodystrophy: a clinical trial." (PubMed)

"Comparing efficacy and costs of four facial fillers in HIV-associated lipodystrophy: a clinical trial." The objective of this study was to evaluate and compare the safety and effectiveness of four different dermal fillers in the treatment of facial lipoatrophy secondary to human immunodeficiency virus.The authors conducted a clinical trial including 147 patients suffering from human immunodeficiency virus-induced lipoatrophy treated with Sculptra (poly-L-lactic acid), Radiesse (calcium (...) . Patient self-evaluation showed a general improvement after the use of facial fillers. Patients reported being satisfied with the treatment and with the reduced impact of lipodystrophy on their quality of life. Despite the nonsignificant differences observed in the number of sessions and volume, autologous fat showed significantly lower costs than all synthetic fillers (p < 0.05).Surgical treatment of human immunodeficiency virus-associated facial lipoatrophy using dermal fillers is a safe

2017 Plastic and reconstructive surgery

74. The Sterility of Partially Used Hyaluronic Acid Fillers After Long Storage. (PubMed)

are an insufficient number of recommendations concerning the safety of storing and reusing dermal fillers in the literature because of the paucity of studies. The aim of this study was to investigate the potential infectious contamination associated with the storage of HA fillers after patient treatment.Hyaluronic acid from previously used syringes was stored at room temperature under sterile conditions for varying durations beginning from 2009. Later, the material was submitted for panculture, including gram (...) -positive and gram-negative bacteria, mycobacteria, and fungi.No fungal or mycobacterial agents were cultured from any of the samples. There were a few positive bacterial cultures, but they were predominantly contaminated with normal skin surface flora.Although it is commonly practiced, the storage of HA fillers after initial patient injection carries a real but small risk of contamination.

2017 Dermatologic Surgery

75. Post Market Study Evaluating Princess Filler Lidocaine for the Correction of Nasolabial Folds

Completion Date : November 19, 2018 Actual Study Completion Date : November 19, 2018 Resource links provided by the National Library of Medicine available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: Princess® FILLER Lidocaine Princess FILLER Lidocaine injections up to 10 ml given to the patients at baseline time point Device: Princess FILLER Lidocaine Princess FILLER Lidocaine injection up to 10 ml given to the patients at baseline time point. After 2 week a touch up (...) -absorbable substance (permanent fillers) in the nasolabial region Facial surgery or implantation of dermal fillers, absorbable and non-absorbable sutures, laser therapy, dermoabrasion, or botulinum toxin application in the nasolabial region within previous twelvemonths, or chemical peeling within previous three months, or planning to undergo such procedures in the treatment area during the study Presence of infectious, inflammatory, or proliferative lesions in the nasolabial region Cutaneous lesions

2017 Clinical Trials

76. Injectable Filler for Facial Soft Tissue Augmentation

Injectable Filler for Facial Soft Tissue Augmentation Injectable Filler for Facial Soft Tissue Augmentation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Injectable Filler for Facial Soft Tissue (...) Summary: The purpose of this study is to assess the safety and performance of Hydroxytite in all subjects who have received sub dermal or deep dermal injections. Condition or disease Wrinkles Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 218 participants Observational Model: Cohort Time Perspective: Retrospective Official Title: An Open-label, Retrospective, Postmarketing Study of Safety and Performance of Hydroxytite, a Calcium Hydroxyapatite

2014 Clinical Trials

77. Permanent and semi-permanent dermal fillers: a systematic review

The skin 1 The ageing process 1 HIV-associated lipodystrophy syndrome 1 Non-surgical therapies for facial augmentation 3 Topical therapies 3 Injectable agents 3 Dermal fillers 4 Types of dermal fillers 4 Temporary fillers 5 Semi-permanent fillers 5 Permanent fillers 5 How dermal fillers work 9 Demand for cosmetic procedures 10 Australian cosmetic industry 10 Summary 11 2. Methodology 12 Literature search protocol 12 Inclusion criteria 12 Literature search strategies 14 Databases searched and search (...) References 91 Appendix A – Excluded studies 101 Appendix B – Study profile tables 104 Appendix C – Treatment data 128 - ASERNIP-S REVIEW OF PERMANENT AND SEMI-PERMANENT DERMAL FILLERS. FEBRUARY 2009 - iv List of Tables Table 1. Classification of dermal fillers by composition 5 Table 2. Classification of injectable semi-permanent and permanent dermal fillers 6 Table 3. Databases searched 14 Table 4. NHMRC hierarchy of evidence 16 Table 5. Summary of included studies 19 Table 6. Dermal fillers for ageing

2009 ASERNIP-S

78. Permanent and semi-permanent dermal fillers: A systematic review

The skin 1 The ageing process 1 HIV-associated lipodystrophy syndrome 1 Non-surgical therapies for facial augmentation 3 Topical therapies 3 Injectable agents 3 Dermal fillers 4 Types of dermal fillers 4 Temporary fillers 5 Semi-permanent fillers 5 Permanent fillers 5 How dermal fillers work 9 Demand for cosmetic procedures 10 Australian cosmetic industry 10 Summary 11 2. Methodology 12 Literature search protocol 12 Inclusion criteria 12 Literature search strategies 14 Databases searched and search (...) References 91 Appendix A – Excluded studies 101 Appendix B – Study profile tables 104 Appendix C – Treatment data 128 - ASERNIP-S REVIEW OF PERMANENT AND SEMI-PERMANENT DERMAL FILLERS. FEBRUARY 2009 - iv List of Tables Table 1. Classification of dermal fillers by composition 5 Table 2. Classification of injectable semi-permanent and permanent dermal fillers 6 Table 3. Databases searched 14 Table 4. NHMRC hierarchy of evidence 16 Table 5. Summary of included studies 19 Table 6. Dermal fillers for ageing

2009 ASERNIP-S

79. Polymethylmethacrylate dermal fillers: evaluation of the systemic toxicity in rats. (PubMed)

Polymethylmethacrylate dermal fillers: evaluation of the systemic toxicity in rats. This study evaluated local and systemic reactions after an intravascular injection of polymethylmethacrylate (PMMA) at two concentrations in a murine model. Thirty rats were divided equally into three groups: 2% PMMA, 30% PMMA, and a control group (normal saline only injection). The filler was injected into the ranine vein. The rats were sedated at 7 and 90 days and a clinical evaluation performed. After (...) presented higher levels of alanine aminotransferase (P = 0.047) after 90 days when compared with the other groups. The data obtained in this study demonstrate that intravascular injections of PMMA fillers show potential health risks such as chronic inflammation at the implantation site.Copyright © 2013 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

2013 International Journal of Oral and Maxillofacial Surgery

80. Perils of dermal fillers. (Full text)

Perils of dermal fillers. With the increasing use of hyaluronic acid-based injectable fillers for cosmetic enhancement a variety of adverse reactions are being reported in the literature. Although most adverse outcomes occur early we describe an interesting case study of a female presenting with granulomatous complications ten years postoperatively. To our knowledge this is one of the longest reported delayed reactions. For the general dental practitioner offering such treatments

2013 British Dental Journal PubMed

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