How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

452 results for

Dermal Filler Injection

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

181. Cellulite: Patient Selection and Combination Treatments for Optimal Results-A Review and Our Experience. (PubMed)

a more algorithmic approach to comprehensively address a condition that affects so many women.A review of the literature surrounding treatment options for cellulite and the authors' experience in this area are provided.This review summarizes available treatment options for cellulite, including topical agents, controlled subcision, energy-based devices, dermal fillers, and new injectable medications. Furthermore, the various ways that these treatments can be combined in an algorithmic and sequential

2019 Dermatologic Surgery

182. Transverse Facial Artery Perforators: Anatomical, Two- and Three-Dimensional Radiographic Study. (PubMed)

artery perforators could be as follows: (1) performing a lateral facial skin flap; (2) facial composite allotransplants; (3) face-lift procedures to improve skin perfusion; and (4) prevention of vessel injury in aesthetic procedures such as dermal filler injection or thread-lift techniques. (...) and their perfusion area.Fourteen hemifaces of fresh adult cadavers from the Department of Anatomy of Lyon University were harvested. Transverse facial artery perforators were identified, dissected, cannulated, and selectively injected with 1 ml of patent blue or contrast solution. Photography, microangiography, and computed tomography were performed. Perforator diameter and localization from the lateral canthus were measured. Exact topography and size of the perforasome were analyzed.Twenty-three transverse

2019 Plastic and reconstructive surgery

183. Long-term follow-up of longevity and diffusion pattern of hyaluronic acid in nasolabial folds correction through high-frequency ultrasound. (PubMed)

Long-term follow-up of longevity and diffusion pattern of hyaluronic acid in nasolabial folds correction through high-frequency ultrasound. Injectable hyaluronic acid (HA) fillers have been widely applied in the clinical treatment for facial wrinkle. However, further information with clinical evidences concerning dermal changes and HA filler longevity post injection as well as diffusion pattern are limited.We evaluated the longevity and diffusion pattern of two HA fillers generated by different (...) crosslinking technologies in the nasolabial folds treatment using high-frequency ultrasound. 41 subjects were treated with Restylane 2 and the remaining 41 with Dermalax DEEP. Wrinkle severity rating scale score and high-frequency ultrasound evaluation of nasolabial folds were performed before and after the injection of HA filler. The ultrasound images were acquired and analyzed to determine dermal thickness and the shape and distribution of HA filler.At two and 24 weeks from baseline, increased dermal

2019 Plastic and reconstructive surgery

184. The case of the eyelid silicone granulomas. (PubMed)

. The patient ultimately underwent a blepharoplasty for improvement of the swelling. Histopathology suggested silicone granulomas of the upper and lower eyelid. This case illustrates the importance of keeping foreign body granulomas on the differential for all patients with a history of facial dermal filler injections. Although hyaluronic acid is the most common dermal filler, providers should suspect the use of other dermal fillers including those not FDA approved particularly when common conservative (...) The case of the eyelid silicone granulomas. Foreign body granulomas can develop even several years after autologous fat or filler injection. In some instances the foreign body granulomas have been found at sites other than the original injection site. We present a case of a 48-year-old male with reported "hyaluronic acid fillers" injected into his upper and lower eyelids several years prior. He subsequently developed periorbital swelling with negative allergic and rheumatologic workup

2019 American Journal of Otolaryngology

185. Long-Term Follow-Up of Longevity and Diffusion Pattern of Hyaluronic Acid in Nasolabial Fold Correction through High-Frequency Ultrasound. (PubMed)

Long-Term Follow-Up of Longevity and Diffusion Pattern of Hyaluronic Acid in Nasolabial Fold Correction through High-Frequency Ultrasound. Injectable hyaluronic acid fillers have been widely applied in the clinical treatment of facial wrinkles. However, further information and clinical evidence concerning dermal changes and hyaluronic acid filler longevity after injection and diffusion pattern are limited.The authors evaluated the longevity and diffusion pattern of two hyaluronic acid fillers (...) generated by different cross-linking technologies used in the treatment of nasolabial folds using high-frequency ultrasound. Forty-one subjects were treated with Restylane 2 and the remaining 41 were treated with Dermalax DEEP. Wrinkle severity rating scale score and high-frequency ultrasound evaluation of nasolabial folds were performed before and after the injection of hyaluronic acid filler. The ultrasound images were acquired and analyzed to determine dermal thickness and the shape and distribution

2019 Plastic and reconstructive surgery

186. Safety and effectiveness of hyaluronic acid fillers in skin of color. (PubMed)

Safety and effectiveness of hyaluronic acid fillers in skin of color. To assess the safety and effectiveness of hyaluronic acid (HA) fillers in skin of color.Two prospective studies followed up subjects with Fitzpatrick skin phototypes of IV, V, or VI for 24 weeks after dermal filler injections. In a double-blind, randomized study, subjects were injected with one of three high concentration (24 mg/mL) HA fillers (Juvéderm Ultra, Ultra Plus, and 30) in one nasolabial fold and Zyplast collagen (...) in the other. In an open-label, randomized study, subjects received one of three low concentration (5.5 mg/mL) HA fillers (Hylaform, Hylaform Plus, and Captique) in both nasolabial folds.A total of 160 subjects (a subset of 439 study subjects) were randomized and treated with one of the three high concentration fillers, and 119 subjects were randomized and treated with one of the three low concentration fillers. For subjects treated with the high concentration fillers there were no occurrences

2009 Journal of cosmetic dermatology

187. Calcium hydroxylapatite tissue filler discovered 6 years after implantation into the nasolabial fold: case report and review. (PubMed)

Calcium hydroxylapatite tissue filler discovered 6 years after implantation into the nasolabial fold: case report and review. Injectable calcium hydroxylapatite is becoming increasingly popular as a facial soft tissue filler, due in part to its purported longevity of esthetic correction compared with other materials, but little is known about its long-term histologic appearance and persistence in facial skin. We recently encountered calcium hydroxylapatite microspheres incidentally during Mohs (...) throughout the reticular dermis associated with focal fibrosis, interstitial mucin, and little surrounding inflammation.Calcium hydroxylapatite microspheres and associated fibrosis may persist in facial dermis at least 6 years after implantation, long after its clinical effects are thought to subside. Dermatologists and dermatopathologists must be mindful of dermal implants because it is likely that incidental encounters will be an increasingly common occurrence.

2009 Dermatologic Surgery

188. Comparative Study of UMA Jeunesse Classic (PubMed)

Comparative Study of UMA Jeunesse Classic The emergence of hyaluronic acid dermal fillers with lidocaine has transformed the minimally invasive treatment of wrinkles, lines and folds of the face. Patients can be treated quickly, painlessly and without the need for large doses of lidocaine. Therefore, it is important to scientifically evaluate the merits of lidocaine-containing products over those without.The two products, with (UJU) and without lidocaine (UJ), were randomly injected (...) into nasolabial folds of 75 healthy volunteers with varying skin types in a split face study, age ranging 26-60 years. Only 73 subjects completed the follow-up. There were 68 females and 5 males with medium-to-deep nasolabial folds. All subjects were randomly injected with the two products on one or the other side of the face. Patients were followed up for 9 months.Both products achieved significant improvement in the wrinkle severity score. Overall results were slightly better with UJU due to ease

2018 Aesthetic plastic surgery

189. A Single-Center Open-Label Study of 1064 nm Nd:YAG for Nonablative Skin Rejuvenation

purposes. Agree to not undergo any other procedure(s) for skin rejuvenation during the study, including but not limited to chemical peel, laser and light based device treatment, and home-use device treatment. Agree to not undergo any injection of botulinum toxin, collagen, hyaluronic acid filler or other dermal filler during the study. Post-menopausal or surgically sterilized, or using a medically acceptable form of birth control at least 3 months prior to enrollment and during the entire course (...) of the study, and no plans to become pregnant or to father a child for the duration of the study. Exclusion Criteria: Participation in a clinical trial of another device or drug within 6 months prior to enrollment or during the study. Any type of prior cosmetic treatment to the target area within 6 months of study participation, such as laser or light-based procedures or surgery. Prior injection to the face of botulinum toxin, collagen, hyaluronic acid filler or other dermal filler within 6 months of study

2018 Clinical Trials

190. Sequential Treatment With BELKYRA® Then Juvéderm® VOLUMA™ With Lidocaine for Overall Improvement in Jawline Contour

any treatment or behavior (e.g., unshaven facial hair; significant changes to dietary or exercise habits) during the subject's participation in the study that may affect the assessments of the submental area Exclusion Criteria: Grade 4 on SMSLG Grade 4 on AJFRS (Allergan Jowl Fat Rating Scale) BMI >35 kg/m2 History of, or current symptoms of dysphagia History of temporary, semi-permanent or permanent facial or neck dermal filler injections below the medial canthi at any time prior to treatment (...) : BELKYRA® and Juvéderm® VOLUMA™ with Lidocaine BELKYRA® is injected into preplaytsmal fat tissue in the submental area. When the Investigator and subject agree that no further intervention is required to achieve the desired result, subjects will be eligible to receive VOLUMA™ treatment. VOLUMA™ is injected along the mandibular border. Drug: BELKYRA® BELKYRA® is injected into preplaytsmal fat tissue in the submental area. When the Investigator and subject agree that no further intervention is required

2018 Clinical Trials

191. Durability, Behavior, and Tolerability of 5 Hyaluronidase Products. (PubMed)

Durability, Behavior, and Tolerability of 5 Hyaluronidase Products. Hyaluronic acid (HA) dermal fillers are commonly used in cosmetic dermatology. Due to differences in their physical characteristics, HA fillers demonstrate different sensitivity to degradation by hyaluronidase (Hase) because of HA concentration and differences in cross-linking. Similarly, there are differences in the activity of Hase products depending on source and concentration.The primary objective was to demonstrate (...) the differences in potency and activity of 5 Hase products when used to degrade 5 different HA products using a human in vivo model.The study subject was a healthy, consenting adult woman scheduled to undergo abdominoplasty. Skin to be excised was injected with 0.1 to 0.2 mL of each filler (10 injections each) leaving a visible lump. Immediately afterward, the HA lumps were injected with 4 IU of each Hase product every 2 minutes until the HA lumps were no longer visible or palpable. This procedure

2018 Dermatologic Surgery

192. Topographic anatomy of the infraorbital artery and its clinical implications for nasolabial fold augmentation. (PubMed)

Topographic anatomy of the infraorbital artery and its clinical implications for nasolabial fold augmentation. Understanding the topography of the blood vessels distributed around the nasolabial fold region is essential for ensuring the safety of dermal filler injections into the nasolabial fold. The purpose of this study was to provide anatomical information on the infraorbital artery distribution and its relationship with the facial artery for use in clinical procedures involving filler (...) injection during nasolabial fold augmentation.The infraorbital artery was investigated in the nasolabial fold region divided into zones I to XII based on clock-hour meridians centered on the infraorbital foramen. The running layers of the infraorbital artery and infraorbital nerve were also compared in the infraorbital foramen. Changes in the infraorbital artery were observed according to vascular dominance of the facial artery.The infraorbital artery was divided into three main branches, palpebral

2018 Plastic and reconstructive surgery

193. Role of Nonsurgical Chin Augmentation in Full Face Rejuvenation: A Review and Our Experience. (PubMed)

Role of Nonsurgical Chin Augmentation in Full Face Rejuvenation: A Review and Our Experience. The chin is a critical component to the perception of facial attractiveness. Dermal fillers offer a nonsurgical, temporary method of correcting mild to moderate chin retrusion and resorption. Thus far, discussion of this procedure has been largely limited to the plastic surgery and otolaryngology literature.To review pertinent aspects of anatomy, patient evaluation, injection technique, concomitant (...) therapies, and complications in chin augmentation using injectable fillers.A brief review of the literature surrounding chin augmentation using injectable fillers, as well as the authors' experience in this area, is provided.Chin augmentation using injectable fillers can be performed effectively and safely with adequate background knowledge of the regional anatomy and appropriate patient selection. The authors discuss both injection techniques in the published literature and their own approach

2018 Dermatologic Surgery

194. Cohesive Polydensified Matrix Hyaluronic Acid for the Treatment of Etched-In Fine Facial Lines: A 6-Month, Open-Label Clinical Trial. (PubMed)

areas showed clinically meaningful and statistically significant improvements in average clinician rating scale scores at all study visits (p < .001 vs baseline). Most subjects reported maintained improvement from baseline of 50% or more throughout the 26-week study. Injection site reactions were mild and resolved without intervention.Cohesive polydensified matrix hyaluronic acid dermal filler treatment was well tolerated and provided consistent and durable improvement in the appearance of a diverse (...) Cohesive Polydensified Matrix Hyaluronic Acid for the Treatment of Etched-In Fine Facial Lines: A 6-Month, Open-Label Clinical Trial. Available hyaluronic acid dermal fillers have unique biophysical properties that influence their clinical utility, longevity, and aesthetic outcomes.To evaluate the effectiveness and durability of a cohesive polydensified matrix hyaluronic acid dermal filler (CPM-HA) for the treatment of etched-in fine facial lines.Subjects with etched-in fine lines

2018 Dermatologic Surgery

195. Calcium hydroxylapatite treatment of human skin: evidence of collagen turnover through picrosirius red staining and circularly polarized microscopy (PubMed)

Calcium hydroxylapatite treatment of human skin: evidence of collagen turnover through picrosirius red staining and circularly polarized microscopy Calcium hydroxylapatite (CaHA, Radiesse®) is a biocompatible, injectable filler for facial soft-tissue augmentation that provides volume to tissues, followed by a process of neocollagenesis for improved skin quality.To examine the effects of CaHA treatment on the molecular organization of collagen using a combination of picrosirius red staining (...) light microscopy provides evidence that subdermal injection of CaHA stimulates the formation of new collagen and dermal remodeling.

Full Text available with Trip Pro

2018 Clinical, cosmetic and investigational dermatology

196. A Study to Evaluate the Safety and Efficacy of Restylane Defyne for Chin Augmentation and Correction of Chin Retrusion

Date : August 21, 2018 Estimated Primary Completion Date : May 2019 Estimated Study Completion Date : May 2020 Arms and Interventions Go to Arm Intervention/treatment Experimental: Restylane Defyne injection with Restylane Defyne Device: Restylane Defyne hyaluronic acid dermal filler gel No Intervention: Control no-treatment control Outcome Measures Go to Primary Outcome Measures : Evaluate effectiveness of the treatment using the Galderma Chin Restrusion Scale [ Time Frame: 12 weeks after last (...) injection ] Effectiveness is defined as change from baseline on the Galderma Chin Retrusion Scale (GCRS; 0=no retrusion, 1=mild retrusion, 2=moderate retrusion, 3=substantial retrusion) Secondary Outcome Measures : Evaluate subject satisfaction using the FACE-Q [ Time Frame: 12 weeks after last injection ] Evaluate effectiveness of the treatment using the Galderma Chin Restrusion [ Time Frame: 24, 36, and 48 weeks after last injection ] Effectiveness is defined as change from baseline Assess overall

2018 Clinical Trials

197. Acellular Adipose Tissue (AAT) for Soft Tissue Reconstruction

Collaborators: U.S. Army Medical Research and Materiel Command Armed Forces Institute of Regenerative Medicine Information provided by (Responsible Party): Johns Hopkins University Study Details Study Description Go to Brief Summary: Although other methods (e.g., autologous fat transfer, dermal-/collagen-based fillers) for soft tissue reconstruction exist, each has distinct disadvantages leaving room for improvement in this treatment area. Investigators in the Elisseeff Laboratory (Johns Hopkins University (...) events to date. Each vial contains a 2 milliliter (mL) dose of the injectable AAT. This volume is similar to other commonly used injectable filler materials intended for soft tissue correction. Outcome Measures Go to Primary Outcome Measures : AAT efficacy for soft-tissue reconstruction in humans to restore volume in soft tissue defects of the trunk [ Time Frame: 6 months post-final injection ] Volume retention documented by pre-to-post injection volumetric changes as detected by 3-dimensional

2018 Clinical Trials

198. Pivotal Study to Evaluate the Effectiveness of a Micro-coring Device Treating Moderate to Severe Facial Wrinkles

months Scar present in the areas to be treated Silicone injections in the areas to be treated Injection of dermal fillers, fat or botulinum toxin, as well as any minimally invasive/invasive medical device for skin treatment, in the study treatment areas, within the past 6 months (i.e., dermabrasion, laser, RF devices) Active smokers (0.5 pack/day) or having quit within 3 months prior to treatment Active, chronic, or recurrent infection History of compromised immune system or currently being treated

2018 Clinical Trials

199. Evaluation of the Ulthera® System and Efficacy Correlation to Morphological Differences

of long-wear makeup (lipstick, lip liner, mascara, etc.) within 48 hours of study photographs and assessments. History of the following cosmetic treatments in the area(s) to be treated: Skin tightening procedure within the past year; Injectable filler of any type within the past: i. 12 months for Hyaluronic acid fillers (e.g. Restylane); ii 12 months for Ca Hydroxyapatite fillers (e.g. Radiesse); iii. 24 months for Long-lasting Hyaluronic acid (Juvéderm Voluma) and Poly-L-Lactic acid fillers (e.g (...) Measures : The average SMAS depth in the eyebrow and lower face regions (cheeks, submental and submandibular) will be compared to quantitative measurements of eyebrow and submental/neck lift [ Time Frame: Day 90 post treatment ] SMAS = Superficial Musculo-Aponeurotic System Secondary Outcome Measures : Determine if there is a correlation between the Clinician Global Aesthetic Improvement Scale (CGAIS) at day 90 and 180 and average Superficial Musculo-Aponeurotic System (SMAS) and average dermal

2018 Clinical Trials

200. Submental Study (Sequential Treatment Approach)

of treatment. Subject has a history of treatment with CoolSculpting or KYBELLA® in the intended treatment area or has a history of any intervention to treat submental fat (e.g., liposuction, surgery, or lipolytic agents). Subject has a history of treatment with radiofrequency, micro-focused ultrasound, laser procedures, chemical peels, or dermal fillers in the neck or chin area within 12 months before the first treatment session. Subject has a history of treatment with botulinum toxin injections (...) Summary: Evaluate the safety and efficacy of subcutaneous fat layer reduction in the submental area using multiple therapeutic tools. Condition or disease Intervention/treatment Phase Body Fat Disorder Device: The ZELTIQ System Drug: Kybella 20 MG in 2 ML Injection Phase 4 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 20 participants Allocation: Non-Randomized Intervention Model: Sequential Assignment Intervention Model

2018 Clinical Trials

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>