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Denver Developmental Screening Test II

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41. Social Determinants of Risk and Outcomes for Cardiovascular Disease

are discussed in the Mechanisms Mediating the Relationship Between Societal Conditions and CVD section. Life-Course Context of SEP For CVD, poor socioeconomic conditions in early life appear to make an important contribution to disease risk in adulthood, especially when early-life factors influence the developmental trajectories of important adult risk factors. A systematic review of 40 studies investigating associations between childhood socioeconomic circumstances and ischemic heart disease, stroke (...) . It involves transparency, outreach, information, and screening. Among US stroke survivors, blacks and Hispanics may have reduced access to stroke preventive care because they have lower median household incomes, have less access to high-quality health care, and are more frequently uninsured. Indeed, in the National Health Interview Survey for the years 2000 through 2006, of 4864 stroke survivors >65 years of age, Mexican Americans and non-Hispanic blacks reported a lower proportion of specialist visits

2015 American Heart Association

42. Child development skills and language in toddlers with cleft lip and palate. (Abstract)

Developmental Screening Test II and MacArthur Communicative Development Inventory - part D, employed for the receptive and expressive vocabulary checklist. Intergroup comparisons were performed using t tests and Chi-square tests. The Pearson correlation coefficient was used to verify the inter-category correlation (p ≤ 0.05).There was statistically significant difference in gross motor, adaptive fine motor, and language skills, both in receptive and expressive aspects, in the comparison between groups (...) Child development skills and language in toddlers with cleft lip and palate. Children born with cleft lip and palate (CLP) are exposed to several risk factors for developmental delay.This cross-sectional and descriptive study compared the performance of gross motor, adaptive fine motor, social-personal and language skills in children with non-syndromic cleft lip and palate (age = 36-47 months, n = 30) matched as to chronological age and gender. The evaluation instruments were Denver

2019 International Journal of Pediatric Otorhinolaryngology

43. Folotyn - pralatrexate

Developmental Therapeutics Program standard procedures. Of the 53 cancer cell lines tested, 36 cell lines (68%) were highly sensitive to the growth inhibitory effect of pralatrexate with GI50’s 30 ml/min might possibly be expected. ? Impaired hepatic function There was no specific study in patients with hepatic impairment. In the non-compartmental co-variate analysis, the laboratory markers Albumin, Bilirubin and Hb were not statistically significant co-variates for pralatrexate clearance. The range (...) function test m 2 square meter MALT mucosa-associated lymphoid tissue mg milligram min minute mL milliliter mos months MTD maximum tolerated dose NCI National Cancer Institute ND not determined NHL non-Hodgkin’s lymphoma NK natural killer NSAID nonsteroidal anti-inflammatory drug NSCLC non-small cell lung cancer OS overall survival PD progressive disease PDCO Paediatric Committee PET positron emission tomography PFS progression-free survival Folotyn CHMP assessment report Rev10.11 Page 7/85 Pgp P

2012 European Medicines Agency - EPARs

44. Home?based Child Development Interventions for Preschool Children from Socially Disadvantaged Families Full Text available with Trip Pro

were not reported. 4.1.6 Outcome measures See Additional Table 10.1. 4.1.6.1 Primary outcomes 4.1.6.1.1 Child cognitive development Six of the seven included studies ( ; ; ; ; ; ) evaluated the impact of the intervention on cognitive development at post‐test using well known reliable and valid tests. used two measures: the Cattell Developmental and Intelligence Scale ( ) and the Stanford Binet Intelligence Test (Terman 1972). also used the Stanford Binet Intelligence Test; while and Infante‐Rivard (...) games and using nursery rhymes with their child at both post‐test and a seven year follow‐up. At post‐test, mothers who read to their child were more likely to be in the intervention group (relative risk (RR) 1.81; 95% CI 1.52 to 2.16, P < 0.0001) and mothers who read to their child daily were more likely to be in the intervention group (RR 2.13; 95% CI 1.34 to 3.38, P < 0.0001). They also reported that mothers in the intervention group more frequently engaged in developmental stimulation games

2012 Campbell Collaboration

45. Cerebrolysin and Neurodevelopment in Preterm Infants

). No Intervention: Control Preterm infants with gestational age less than 32 weeks at birth will receive routine care. Outcome Measures Go to Primary Outcome Measures : Neurodevelopmental outcome [ Time Frame: 9 months ] Assessment of the physical and mental functions of preterm infant by Denver Developmental Screening Test II (DDST II) Secondary Outcome Measures : Side effects of cerebrolysin therapy [ Time Frame: 9 months ] Sweating, dizziness, increased heart rate and arrhythmia, loss of appetite, diarrhea (...) by (Responsible Party): Nehad Nasef, Mansoura University Children Hospital Study Details Study Description Go to Brief Summary: The overall aim of the study is to assess the effect of Cerebrolysin on physical and mental development of preterm infants by Denver Scale II at different ages of 5, 7 and 12 months Condition or disease Intervention/treatment Phase Infant Development Cerebral Palsy Preterm Infant Drug: Cerebrolysin Phase 1 Detailed Description: There is an inverse relationship between birth weight

2018 Clinical Trials

46. Diagnosis and Management of Bronchiolitis Obliterans Syndrome: An Official ATS/ERS/ISHLT Clinical Practice Guideline

, a spirometric pattern that is usually obstructive, and an essentially clear chest radiograph [4]. However, OB is difficult to detect via transbronchial lung biopsy and cannot be confidently diagnosed via noninvasive testing [6–10]. Therefore, previously published consensus statements have designated a persistent decline in FEV1 to f80% of baseline post-transplant FEV1 that is present for a minimum of 3 weeks (in the absence of confounding conditions) as a surrogate marker of probable OB, and such FEV1 (...) obliterans organising pneumonia (BOOP) ii) Fibrinoid and organising pneumonia (FOP) b) Chronic inflammation of airways i) Large airways (bronchiectasis # , bronchomalacia) ii) Bronchioles (follicular or exudative bronchiolitis) c) Chronic pleural inflammation d) Chronic vascular rejection 5) Infection 6) Surgical removal of lung tissue 7) Mechanical abnormality a) Airway dysfunction i) Anastomotic stricture/stenosis ii) Bronchomalacia (allograft, native airway in SLT) b) Allograft compression i) Weight

2014 American Thoracic Society

47. Treatment and recommendations for homeless people with Opioid Use Disorders

of Primary Health Care. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the Health Resources & Services Administration. Health Care for the Homeless Clinicians’ Network ADAPTING YOUR PRACTICE: Recommendations for the Care of Homeless Patients with Opioid Use Disorders ii PREFACE Clinicians experienced in homeless health care routinely adapt their practice to foster better outcomes for their patients. This document was written for health (...) Bascelli, MD Medical Director, Project H.O.P.E. (Homeless Outreach Program Enrichment) Camden, New Jersey Pooja Bhalla, RN, BSN Program Director of Nursing & Associate Director Clinical Operations Boston Health Care for the Homeless Program Boston, Massachusetts Gary Cobb Peer Mentor & Community Activist Central City Concern Portland, Oregon Elizabeth Cookson, MD, DFAPA Director of Psychiatry Colorado Coalition for the Homeless Denver, Colorado Maya Doe-Simkins, MPH Training & Technical Assistance

2014 National Health Care for the Homeless Council

48. American College of Medical Genetics and Genomics guideline for the clinical evaluation and etiologic diagnosis of hearing loss

by a fee-for-service laboratory that offers diagnostic testing for hearing loss. The other authors declare no conflict of interest. REFERENCES 1. Finitzo T , Albright K, O’Neal J. The newborn with hearing loss: detection in the nursery. Pediatrics 1998;102:1452–1460. 2. Yoshinaga-Itano C, Coulter D, Thomson V. Developmental outcomes of children with hearing loss born in Colorado hospitals with and without universal newborn hearing screening programs. Semin Neonatol 2001;6:521–529. 3. American Academy (...) FOR THE ETIOLOGIC DIAGNOSIS OF HEREDITARY HEARING LOSS Historically, molecular diagnostic tests for hearing loss have used genotyping or DNA sequencing to identify specific hear - ing loss variants or to screen individual genes, or small collec- tions of genes, for changes associated with hearing loss. This approach has proven to be effective in cases in which there is a single gene, or limited number of genes, responsible for a subtype of hearing loss. Examples include SLC26A4 gene sequencing in individuals

2014 American College of Medical Genetics and Genomics

49. An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome

[ – ]. Post-transplant OB is characterised by progressive obliteration of small airways ( ) that is typically accompanied by a persistent decline in spirometric measures of lung function, a spirometric pattern that is usually obstructive, and an essentially clear chest radiograph [ ]. However, OB is difficult to detect via transbronchial lung biopsy and cannot be confidently diagnosed via noninvasive testing [ – ]. Therefore, previously published consensus statements have designated a persistent decline (...) of HLA class I and class II antigens on epithelial cells [ , ], and stimulates and augments the generation of allogeneic immune responses and pro-inflammatory cytokines [ , ]. Transient bacterial airway colonisation can significantly increase BAL neutrophils and other indicators of lung inflammation [ ]. B otha et al . [ ] examined 155 consecutive lung transplants and reported that de novo allograft colonisation with Pseudomonas aeruginosa was strongly associated with developing BOS within 2 years

2014 International Society for Heart and Lung Transplantation

50. The International Society for Heart and Lung Transplantation Guidelines for the management of pediatric heart failure

in the index case. Level of Evidence C Class IIa 1. Genetic testing can be useful for patients with familial DCM to confirm the diagnosis, to recognize those who are at highest risk of arrhythmia and syndromic features, to facilitate cascade screening within the family, and to help with family planning. Level of Evidence C Hypertrophic cardiomyopathy x 9 Ackerman, M.J., Priori, S.G., Willems, S. et al. HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies (...) cardiomyopathies: molecular genetics and clinical genetic testing in the postgenomic era. J Mol Diagn . 2013 ; 15 : 158–170 | | | | | , x 13 Kindel, S.J., Miller, E.M., Gupta, R. et al. Pediatric cardiomyopathy: importance of genetic and metabolic evaluation. J Card Fail . 2012 ; 18 : 396–403 | | | | | Class IIa 1. Genetic testing is indicated in the most clinically affected individual to facilitate screening. Level of Evidence A 2. Mutation-specific genetic testing is recommended for first-degree family

2014 International Society for Heart and Lung Transplantation

51. Treatment of Depression During Pregnancy and the Postpartum Period

length of stay o Infant attachment o Developmental screening—Ages and Stages Questionnaire; Denver; Modified Checklist for Autism in Toddlers; Bayley Scales of Infant Development • Growth and development after 1 year of age: o Developmental screening and diagnoses o Growth parameters (height, weight, and body mass index percentile according to sex and age) • Learning (e.g., linguistic, cognitive, and social-emotional skills) and educational achievement o Kindergarten readiness o Age at Kindergarten (...) confronting women with perinatal depression. Finally, we will identify issues that future studies should address so that the woman with perinatal depression, health care providers, and other stakeholders can make optimally informed decisions. II. The Key Questions The Agency for Healthcare Research and Quality (AHRQ) wrote preliminary Key Questions (KQs) based on input from the topic nominator. The Pacific Northwest Evidence-based Practice Center (PNW EPC) revised the KQs and developed eligibility

2014 Effective Health Care Program (AHRQ)

52. Guidelines for the Clinical and Operational Management of Drug-Resistant Tuberculosis

to antimicrobial agents have been identi? ed. Resistance to some antimicrobials is primarily linked to a limited number of bacterial chromosomal mutations, while oth- ers have a variety of associated mutations. These mutations are the target of diagnostic tests used to screen patients presenting with symptoms suggestive of TB and to detect resistance more rapidly. Every large population of micro- organisms (as might be found in patients with sputum smear-positive and cavitary pulmonary TB) contains some (...) ? oxacin Cm capreomycin CPC cetylpyridinium chloride Cs cycloserine DALY disability-adjusted years of life DM diabetes mellitus DOT directly observed treatment DOTS originally an acronym for directly observed treatment, short course, DOTS became the term used to describe the tuberculosis control strategy recommended by the WHO DR-TB drug-resistant tuberculosis DST drug susceptibility testing E ethambutol EBA early bactericidal activity Eth ethionamide FDA ? uorescein diacetate used for vital staining

2013 International Union Against TB and Lung Disease

53. Genetics and Genomics for the Prevention and Treatment of Cardiovascular Disease: Update Full Text available with Trip Pro

demonstrated that elevated LDL-C and reduced high-density lipoprotein cholesterol are CVD risk factors. Because at least half of the variation in serum cholesterol and other lipids can be explained by genetic variation, , unraveling the genetic pathogenesis of hypercholesterolemia and other lipid abnormalities could reap significant public health benefits by providing a knowledge base for the development of novel treatments or screening tests to determine who would most benefit from lifestyle modification (...) to understand mechanisms, and identification of therapeutic targets. For single-gene CVDs, progress has led to several clinically useful diagnostic tests, extending our ability to inform the management of afflicted patients and their family members. However, there has been little progress in developing genetic testing for complex CVD because individual common variants have only a modest impact on risk. The study of the genomics of complex CVDs is further challenged by the influence of environmental

2013 American Heart Association

54. Classification, Evaluation, and Management of Childhood Interstitial Lung Disease in Infancy: An Official ATS Clinical Practice Guideline

, Lawrence M. Nogee, and Gregory J. Redding; on behalf of the American Thoracic Society Committee on Childhood Interstitial Lung Disease (chILD) and the chILD Research Network THISOFFICIALSTATEMENTOFTHEAMERICANTHORACICSOCIETY(ATS) WASADOPTEDBYTHEATSBOARDOFDIRECTORS,FEBRUARY2013 Contents Executive Summary Diagnosis Special Considerations Management Research Priorities Introduction Methods Classi?cation De?nitions Epidemiology Diagnostic Evaluation Overview Diagnostic Tests Age-Speci?c Considerations (...) areas for future re- search. Conclusions: After common causes of DLD are excluded, neonates and infants with childhood ILD syndrome should be evaluated by aknowledgeablesubspecialist.Theevaluationmayincludeechocar- diography, controlled ventilation high-resolution computed to- mography,infantpulmonaryfunctiontesting,bronchoscopywith bronchoalveolar lavage, genetic testing, and/or lung biopsy. Pre- ventivecare,familyeducation,andsupportareessential. Keywords: diffuse lung disease; lung growth

2013 American Thoracic Society

55. Hip Pain and Mobility Deficits ? Hip Osteoarthritis

walk test, 30-second chair stand, stair measure, timed up-and-go test, self-paced walk, timed single- leg stance, 4-square step test, and step test. A Clinicians should measure balance performance and activities that predict the risk of falls in adults with hip osteoarthritis, especially those with decreased physical function or a high risk of falls because of past history. Recommended balance tests for patients with osteoarthritis include the Berg Balance Scale, 4-square step test, and timed (...) single-leg stance test. F Clinicians should use published recommendations from the Academy of Geriatric Physical Therapy of the American Physical Therapy Association 6 to guide fall risk management in patients with hip osteoarthritis to assess and manage fall risk. EXAMINATION – PHYSICAL IMPAIRMENT MEASURES 2017 Recommendation A When examining a patient with hip pain/hip osteoarthritis over an episode of care, clinicians should document the flexion, ab - duction, and external rotation (F ABER

2017 The Orthopaedic Section of the American Physical Therapy Association (APTA), Inc.

56. Neurodevelopmental Outcomes in Children With Congenital Heart Disease: Evaluation and Management Full Text available with Trip Pro

the available literature addressing developmental disorder and disability and developmental delay in the CHD population, with specific attention given to surveillance, screening, evaluation, and management strategies. MEDLINE and Google Scholar database searches from 1966 to 2011 were performed for English-language articles cross-referencing CHD with pertinent search terms. The reference lists of identified articles were also searched. The American College of Cardiology/American Heart Association (...) classification of recommendations and levels of evidence for practice guidelines were used. A management algorithm was devised that stratified children with CHD on the basis of established risk factors. For those deemed to be at high risk for developmental disorder or disabilities or for developmental delay, formal, periodic developmental and medical evaluations are recommended. A CHD algorithm for surveillance, screening, evaluation, reevaluation, and management of developmental disorder or disability has

2012 American Heart Association

57. Educational and Psychological Interventions to Improve Outcomes for Recipients of Implantable Cardioverter Defibrillators and Their Families Full Text available with Trip Pro

for primary prevention has been expanded. ICDs are recommended as primary prevention in the HF guidelines to reduce total mortality in patients who have class II to III HF while undergoing optimal medical therapy and who have reasonable expectation of survival for >1 year with good functional status. Even though the number of ICD implantations has increased over the past few years as indications and guidelines have changed, , it is difficult to use these numbers for future projections. With up to 54 (...) , respectively, with psychological distress. Approximately 58% to 70% of ICD patients with emotional distress receive no treatment. The psychological problems in ICD patients may be heightened by or contribute to other symptoms such as sleep disturbances. Although the majority of patients do well with their device, and positive life experiences after ICD implantation have been reported, these results suggest that systematic clinical strategies to screen and treat those who are distressed are indicated

2012 American Heart Association

58. KDIGO Clinical Practice Guideline for Acute Kidney Injury

21 Table 5. Causes of AKI and diagnostic tests 22 Table 6. Causes of AKI: exposures and susceptibilities for non-specific AKI 23 Table 7. AKI diagnosis 28 Table 8. Overview of the approaches to determine baseline SCr in the application of RIFLE classification in previous studies 29 Table 9. Estimated baseline SCr 29 Table 10. AKI staging 30 Table 11. Definitions of AKI, CKD, and AKD 33 Table 12. Examples of AKI, CKD, and AKD based on GFR and increases in SCr 33 Table 13. Markers of kidney damage (...) will inevitably and appropriately occur when clinicians take into account the needs of individual patients, available resources, and limitations unique to an institution or type of practice. Every health-care professional making use of these recommendations is responsible for evaluating the appropriateness of applying them in the setting of any particular clinical situation. The recommendations for research contained within this document are general and do not imply a speci?c protocol. SECTION II: DISCLOSURE

2012 National Kidney Foundation

59. Decision Making in Advanced Heart Failure

). ? Benefits and risks of noncardiac procedures should be reviewed in the context of competing risks for death and functional limitation attributable to heart failure (eg, hip replacement, repair of asymptomatic aortic aneurysm, or screening tests). ? Decisions for major cardiac and noncardiac interventions should include consideration of “what if” situations of unanticipated adversity. ? Referral to a palliative care team should be considered for assistance with difficult decision making, symptom man (...) influenza vaccination or at 1-year increments roughly originating from the date of diagnosis. It may be convenient to have this review occur in temporal proximity to an annual general medical evaluation, particularly with regard to screening studies, for which the indications might change in the setting of progressive heart disease. Intheannualreviewvisit(Table5),avarietyoftaskscould be accomplished. Patients could summarize their recent symptom burden and quality of life. Goals for the coming year

2012 American Heart Association

60. Genetics of Skin Cancer (PDQ®): Health Professional Version

and potential chemopreventive agent, is also being studied for potential palliative effects for keratocystic odontogenic tumors in patients with BCNS. Psychosocial and Behavioral Issues Most of the psychosocial literature about hereditary skin cancers has focused on patients with familial melanoma. In individuals at risk of familial melanoma, influence decisions about genetic testing for inherited cancer risk and risk-management strategies. for pathogenic variants in CDKN2A is generally high. Perceived (...) benefits among individuals with a strong family history of melanoma include information about the risk of melanoma for themselves and their children and increased motivation for sun-protective behavior. A number of studies have examined in individuals with a family history of melanoma. Overall, these studies indicate inconsistent adoption and maintenance of these behaviors. Intervention studies have targeted knowledge about melanoma, sun protection, and screening behaviors in family members of melanoma

2016 PDQ - NCI's Comprehensive Cancer Database

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