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Deep Vein Thrombosis of the Upper Extremity

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41. PFO closure in high-risk patient with paradoxical arterial embolism, deep vein thrombosis, pulmonary embolism and factor V Leiden genetic mutation Full Text available with Trip Pro

PFO closure in high-risk patient with paradoxical arterial embolism, deep vein thrombosis, pulmonary embolism and factor V Leiden genetic mutation Occurrence of paradoxical arterial embolism may cause the first symptoms in patients with a coexisting hypercoagulable state and patent foramen ovale (PFO). This can result in significant morbidity and mortality depending on the location of the embolism. The risks and benefits of closure of small PFOs have not been well elucidated in prior studies (...) % on supplemental oxygen. He had a cool left upper extremity and the patient described subjective paresthesias in this extremity. Left radial pulse was difficult to palpate. Physical exam was otherwise unremarkable. Troponin I was mildly elevated at 0.217 ng/l. White blood cell count was 11.8 and INR 1.1. EKG showed sinus tachycardia with non-specific T abnormalities in the anterior leads. His past medical history was notable for only hypertension and hyperlipidemia. Current recommendation is for antiplatelet

2018 Oxford Medical Case Reports

42. CRACKCast E088 – Pulmonary Embolism & Deep Venous Thrombosis

discussion) Fondaparinux Apixaban Rivaroxaban OR heparin infusion after a loading bolus Ideally transition to oral anticoagulation at least 3 months (some up to 12 months) Encourage ambulation as much as possible Bedrest promotes DVT extension, risk of embolization, and post-DVT syndrome 8) What are the common causes of upper limb DVT? Upper limb DVT = thrombosis in the axillary vein “ The deep veins of the upper extremity include the paired ulnar, radial and interosseous veins in the forearm, paired (...) of the lung that are ventilated (dead space) not being perfused. Chest pain: thought due to a focal area of lung tissue necrosis (caused by intensive inflammatory processes) Hypotension: impaired LV filling 5) What is Paget-Schroetter Syndrome? “ Effort thrombosis, or Paget-Schroetter Syndrome, refers to axillary-subclavian vein thrombosis associated with strenuous and repetitive activity of the upper extremities. Anatomical abnormalities at the thoracic outlet and repetitive trauma to the endothelium

2017 CandiEM

43. Recurrent Upper Extremity Thrombosis Associated with Overactivity: A Case of Delayed Diagnosis of Paget-Schroetter Syndrome Full Text available with Trip Pro

Recurrent Upper Extremity Thrombosis Associated with Overactivity: A Case of Delayed Diagnosis of Paget-Schroetter Syndrome Paget-Schroetter syndrome is thrombosis of the axillary-subclavian vein that is associated with strenuous and repetitive activity of the upper extremities. Overuse of the arm coupled with external compression results in microtrauma in the intima of the subclavian vein, resulting in the activation of the coagulation cascade. Diagnosis is usually made by Doppler ultrasound (...) and the treatment involves thrombolysis, while routine surgical decompression of the thoracic outlet is controversial. In this report, we present a case of a patient who presented with a second episode of spontaneous right upper extremity deep venous thrombosis. The first episode was inadequately treated with oral anticoagulation alone. During the second episode, Paget-Schroetter syndrome was diagnosed, after careful review of his occupational history. He subsequently underwent angioplasty and decompression

2017 Case reports in vascular medicine

44. Thrombus Burden of Deep Vein Thrombosis and Its Association with Thromboprophylaxis and D-Dimer Measurement: Insights from the APEX Trial. Full Text available with Trip Pro

Thrombus Burden of Deep Vein Thrombosis and Its Association with Thromboprophylaxis and D-Dimer Measurement: Insights from the APEX Trial. Background The aim of this study was to evaluate the effect of betrixaban on the occurrence of deep vein thrombosis (DVT) and also the extent of thrombus and to assess the association of baseline D-dimer with subsequent thrombus burden. Methods In the APEX trial (ClinicalTrials.gov: NCT01583218), 7,513 acutely ill hospitalized medical patients were randomly (...) assigned to extended-duration betrixaban (35–42 days) or enoxaparin (10 ± 4 days). D-dimer concentration was measured at baseline, and mandatory lower-extremity compression ultrasonography (CUS) was performed at 35 to 42 days. The thrombus burden of DVT was assessed by the number of non-compressible vascular segments in six target proximal veins and compared between treatment groups and D-dimer categories (≥2 × upper limit of normal [ULN] versus <2 × ULN). Results Compared with enoxaparin, extended

2017 Thrombosis and haemostasis

45. Central Venous Catheter (CVC) Associated Deep Vein Thrombosis (DVT) in Cancer Patients

not have to be taken out because of the clot. Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 70 participants Observational Model: Cohort Time Perspective: Prospective Official Title: A Pilot Study in Cancer Patients With Central Venous Catheter (CVC) Associated Deep Vein Thrombosis (DVT) in the Upper Extremity Treated With Low Molecular Weight Heparin (LMWH) and Apixaban (Catheter 3) Actual Study Start Date : May 15, 2017 Estimated Primary (...) -Probability Sample Study Population Cancer patients with central venous catheter associated deep vein thrombosis in the upper extremity Criteria Inclusion Criteria: Male or female > 18 years of age. Symptomatic acute upper limb thrombosis in the axillary, subclavian or internal jugular veins, with or without pulmonary embolism, associated with central venous catheter objectively documented by compression ultrasonography, venogram or Computerized Tomography (CT) scan. Diagnosis of active malignancy

2017 Clinical Trials

46. Incidence of Deep Vein Thrombosis on Central Venous Catheters in the Post Operative Period of Carcinologic Surgery

Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Thrombosis Critical Illness Venous Thrombosis Upper Extremity Deep Vein Thrombosis Embolism and Thrombosis Vascular Diseases Cardiovascular Diseases Disease Attributes Pathologic Processes (...) Incidence of Deep Vein Thrombosis on Central Venous Catheters in the Post Operative Period of Carcinologic Surgery Incidence of Deep Vein Thrombosis on Central Venous Catheters in the Post Operative Period of Carcinologic Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2017 Clinical Trials

47. Upper extremity deep venous thrombosis and pulmonary embolus after ovarian hyperstimulation Full Text available with Trip Pro

Upper extremity deep venous thrombosis and pulmonary embolus after ovarian hyperstimulation A healthy female presented with upper extremity (UE) swelling of several days duration. Admission laboratories were normal except for an elevated D-dimer. An UE ultrasound with Doppler revealed a thrombus in the right subclavian vein. A subsequent chest CT angiogram further characterised the subclavian vein thrombus and also identified a pulmonary embolus. A thorough history and laboratory evaluation (...) showed that her only risk factors were long-time contraceptive pills and a recent cycle of ovarian hyperstimulation (OH) 7 weeks prior to presentation. Anticoagulation treatment was started and the patient's remaining outpatient work-up was negative for all other hereditary causes. A complete anatomic work-up showed bilateral thoracic outlet syndrome (TOS). A review of the literature on the occurrence of upper extremity deep venous thrombosis suggests that these usually occur in the presence

2016 BMJ case reports

48. Apixaban for Routine Management of Upper Extremity Deep Venous Thrombosis

, 2018 See Sponsor: Intermountain Health Care, Inc. Collaborators: Bristol-Myers Squibb Pfizer Information provided by (Responsible Party): Scott C. Woller, MD, Intermountain Health Care, Inc. Study Details Study Description Go to Brief Summary: This study will assess the safety and effectiveness of a drug called apixaban for the treatment of upper extremity deep vein thrombosis (UEDVT) and clinically important bleeding. Subjects will receive apixaban 10 mg by mouth twice a day for 7 days, followed (...) ; however, it is hoped that the information obtained from this research study will help treat patients in the future. Condition or disease Intervention/treatment Phase Deep Venous Thrombosis Upper Extremity Deep Venous Thrombosis Thrombus Venous Thromboembolism Deep Vein Thrombosis Drug: apixaban Phase 4 Detailed Description: Background: Upper extremity deep vein thrombosis (UEDVT) constitutes approximately 10% of all DVT. A recent increase in incidence is largely secondary to the increasing use

2016 Clinical Trials

49. Upper extremity deep vein thrombosis in hospitalized patients: a descriptive study. (Abstract)

Upper extremity deep vein thrombosis in hospitalized patients: a descriptive study. Increasingly, there is a focus on the prevention of hospital-acquired conditions including venous thromboembolism. Many studies have evaluated pulmonary embolism and lower extremity deep vein thrombosis, but less is known about upper extremity deep vein thrombosis (UEDVT) in hospitalized patients. The objective of this study was to describe UEDVT incidence, associated risks, outcomes, and management in our (...) in-hospital mortality. Most UEDVTs were treated even in the absence of concurrent lower extremity deep vein thrombosis or pulmonary embolism. Additional research is needed to modify risks and optimize outcomes. Journal of Hospital Medicine 2014;9:48-53. © 2013 Society of Hospital Medicine. © 2013 Society of Hospital Medicine.

2014 Journal of Hospital Medicine

50. Postthrombotic syndrome following upper extremity deep vein thrombosis in children. Full Text available with Trip Pro

Postthrombotic syndrome following upper extremity deep vein thrombosis in children. Despite its relatively estimated high occurrence, the characterization of pediatric upper extremity deep vein thrombosis (UE-DVT) and of UE postthrombotic syndrome (PTS) is still lacking. We investigated the occurrence, characteristics, and predictors of UE-PTS in a cohort of children with objectively confirmed UE-DVT. Patients were analyzed in 3 groups according to DVT pathogenesis and neonatal status: primary

2014 Blood

51. Upper extremity deep vein thrombosis central venous catheters-related and pulmonary embolism after cardiac surgery. (Abstract)

Upper extremity deep vein thrombosis central venous catheters-related and pulmonary embolism after cardiac surgery.

2014 Chest

52. Upper Extremity Deep Vein Thromboses: The Bowler and the Barista Full Text available with Trip Pro

Upper Extremity Deep Vein Thromboses: The Bowler and the Barista Effort thrombosis of the upper extremity refers to a deep venous thrombosis of the upper extremity resulting from repetitive activity of the upper limb. Most cases of effort thrombosis occur in young elite athletes with strenuous upper extremity activity. This article reports two cases who both developed upper extremity deep vein thromboses, the first being a 67-year-old bowler and the second a 25-year-old barista, and illustrates (...) that effort thrombosis should be included in the differential diagnosis in any patient with symptoms concerning DVT associated with repetitive activity. A literature review explores the recommended therapies for upper extremity deep vein thromboses.

2016 Case reports in vascular medicine

53. Upper Extremity DVT versus Lower Extremity DVT: Perspectives from the GARFIELD-VTE Registry. (Abstract)

Upper Extremity DVT versus Lower Extremity DVT: Perspectives from the GARFIELD-VTE Registry. Upper extremity deep vein thrombosis (UEDVT) is less common than lower extremity DVT (LEDVT) and consequently less well characterized. This study compared clinical characteristics and 1-year outcomes between 438 UEDVT patients and 7,602 LEDVT patients recruited in the GARFIELD-VTE registry. UEDVT patients were significantly more likely to have a central venous catheter than those with LEDVT (11.5% vs

2019 Thrombosis and haemostasis

54. Incidence and risk factors of superficial and deep vein thrombosis associated with peripherally inserted central catheters in children (Abstract)

decrease this complication.Background Upper-extremity venous thrombosis is associated with the use of peripherally inserted central catheters (PICCs). Few pediatric studies have focused on this issue. Objectives To determine the incidence and risk factors for PICC-related superficial vein thrombosis (SVT) and deep vein thrombosis (DVT) in children. Patients/methods An observational follow-up cohort study was conducted at a single hospital between June 2012 and June 2015. All patients receiving a PICC (...) Incidence and risk factors of superficial and deep vein thrombosis associated with peripherally inserted central catheters in children Essentials Pediatric studies on peripherally inserted central catheter (PICC)-related thrombosis are scarce. This study analyzes incidence and risk factors for PICC-related venous thrombosis in children. PICC-related thrombosis is a common, and nearly always, asymptomatic complication. Echo-guided insertion and a catheter to vein ratio < 0.33 may notably

2016 EvidenceUpdates

55. Deep Vein Thrombosis

-thrombotic syndrome: >50% Venous at 5 years in nearly half of patients Efficacy data (some studies question longterm benefit) Normal vein after Catheter : 45% (contrast with 0% after alone) Decreases risk of long term , post-phlebitic syndrome, stasis ulcers Best outcome if performed early (within 2 weeks) Poor efficacy if prior Deep Vein Thrombosis References Other indications Massive proximal extremity DVT with severe symptoms or XII. Complications Post-thrombotic syndrome (postphlebitic syndrome (...) -GLOSS) The formation of a blood clot in a deep vein of the leg or lower pelvis. Symptoms may include pain, swelling, warmth, and redness in the affected area. Definition (NCI) A blood clot in a deep vein, predominantly in the lower extremity, but may include the pelvis or upper extremity.(NICHD) Definition (NCI_CDISC) A blood clot (thrombus) in a deep vein in the lower extremity. Concepts Disease or Syndrome ( T047 ) MSH ICD10 SnomedCT 128053003 , 128057002 , 195403006 , 266328001 , 155454004 LNC

2018 FP Notebook

56. Micropuncture Access Set Use During Implantation of Totally Implantable Venous Access Device May Reduce Upper Extremity DVT Incidence Among Patients Undergoing Chemotherapy for Colorectal Cancer. (Abstract)

%), and the rate and incidence of venous thrombosis were significantly higher in the CS group. There were no significant differences between the groups in other complications such as the rate of port site infection, deep vein thrombosis, obstruction, catheter dislocation, and skin complications (exposure). No incidence of catheter infection, port rotation, intraoperative bleeding, or pneumothorax was observed in this cohort.MS is a safe and feasible procedure and results in less thrombosis. MS may play (...) Micropuncture Access Set Use During Implantation of Totally Implantable Venous Access Device May Reduce Upper Extremity DVT Incidence Among Patients Undergoing Chemotherapy for Colorectal Cancer. The aim of this study was to compare the perioperative outcomes when using a micropuncture access set (MS) to those when using a conventional puncture set (CS) for implantation of totally implantable venous access device (TAVID).A total of 314 patients undergoing chemotherapy for colorectal cancer were

2020 World Journal of Surgery

57. Thrombolysis for acute upper extremity deep vein thrombosis [Cochrane Protocol]

Thrombolysis for acute upper extremity deep vein thrombosis [Cochrane Protocol] Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address: Timing

2016 PROSPERO

58. Deep Vein Thrombosis of the Upper Extremity

Deep Vein Thrombosis of the Upper Extremity Deep Vein Thrombosis of the Upper Extremity Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration (...) 4 Deep Vein Thrombosis of the Upper Extremity Deep Vein Thrombosis of the Upper Extremity Aka: Deep Vein Thrombosis of the Upper Extremity , Upper Extremity DVT , PICC Line Thrombosis From Related Chapters II. Causes Central Venous Catheter (common) PICC Line Thrombosis (complicates 3-5% of s) External Vein Compression (Effort Thrombosis) Athletes with muscle hypertrophy Idiopathic (rare) Evaluate for occult cancer Consider evaluation for state III. Symptoms or of the hand or arm IV. Signs Arm

2015 FP Notebook

59. Upper extremity deep vein thrombosis Full Text available with Trip Pro

Upper extremity deep vein thrombosis A 56-year-old female, recently (3 months) diagnosed with chronic kidney disease (CKD), on maintenance dialysis through jugular hemodialysis lines with a preexisting nonfunctional mature AV fistula made at diagnosis of CKD, presented to the hospital for a peritoneal dialysis line. The recently inserted indwelling dialysis catheter in left internal jugular vein had no flow on hemodialysis as was the right-sided catheter which was removed a day before insertion (...) AV fistula for which a fistula closure was done. Absence of relief of edema prompted a further computed tomography (CT) angiogram (since it was not possible to evaluate the more proximal venous segments due to edema and presence of clavicle). Ct angiogram revealed central vein thrombosis for which catheter-directed thrombolysis and venoplasty was done resulting in complete resolution of signs and symptoms. Upper extremity DVT (UEDVT) is a very less studied topic as compared to lower extremity DVT

2012 International journal of critical illness and injury science

60. Diagnosis and management of upper extremity deep-vein thrombosis in adults. Full Text available with Trip Pro

Diagnosis and management of upper extremity deep-vein thrombosis in adults. Upper extremity deep-vein thrombosis (UEDVT) is common and can cause important complications, including pulmonary embolism and post-thrombotic syndrome. An increase in the use of central venous catheters, particularly peripherally inserted central catheters has been associated with an increasing rate of disease. Accurate diagnosis is essential to guide management, but there are limitations to the available evidence (...) with suspected deep-vein thrombosis of the upper extremity.

2012 Thrombosis and haemostasis

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