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Deep Vein Thrombosis of the Upper Extremity

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41. PFO closure in high-risk patient with paradoxical arterial embolism, deep vein thrombosis, pulmonary embolism and factor V Leiden genetic mutation (PubMed)

PFO closure in high-risk patient with paradoxical arterial embolism, deep vein thrombosis, pulmonary embolism and factor V Leiden genetic mutation Occurrence of paradoxical arterial embolism may cause the first symptoms in patients with a coexisting hypercoagulable state and patent foramen ovale (PFO). This can result in significant morbidity and mortality depending on the location of the embolism. The risks and benefits of closure of small PFOs have not been well elucidated in prior studies (...) % on supplemental oxygen. He had a cool left upper extremity and the patient described subjective paresthesias in this extremity. Left radial pulse was difficult to palpate. Physical exam was otherwise unremarkable. Troponin I was mildly elevated at 0.217 ng/l. White blood cell count was 11.8 and INR 1.1. EKG showed sinus tachycardia with non-specific T abnormalities in the anterior leads. His past medical history was notable for only hypertension and hyperlipidemia. Current recommendation is for antiplatelet

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2018 Oxford Medical Case Reports

42. Incidence and risk factors of superficial and deep vein thrombosis associated with peripherally inserted central catheters in children

decrease this complication.Background Upper-extremity venous thrombosis is associated with the use of peripherally inserted central catheters (PICCs). Few pediatric studies have focused on this issue. Objectives To determine the incidence and risk factors for PICC-related superficial vein thrombosis (SVT) and deep vein thrombosis (DVT) in children. Patients/methods An observational follow-up cohort study was conducted at a single hospital between June 2012 and June 2015. All patients receiving a PICC (...) Incidence and risk factors of superficial and deep vein thrombosis associated with peripherally inserted central catheters in children Essentials Pediatric studies on peripherally inserted central catheter (PICC)-related thrombosis are scarce. This study analyzes incidence and risk factors for PICC-related venous thrombosis in children. PICC-related thrombosis is a common, and nearly always, asymptomatic complication. Echo-guided insertion and a catheter to vein ratio < 0.33 may notably

2016 EvidenceUpdates

43. Upper extremity deep vein thrombosis central venous catheters-related and pulmonary embolism after cardiac surgery. (PubMed)

Upper extremity deep vein thrombosis central venous catheters-related and pulmonary embolism after cardiac surgery.

2014 Chest

44. Upper extremity deep vein thrombosis in hospitalized patients: a descriptive study. (PubMed)

Upper extremity deep vein thrombosis in hospitalized patients: a descriptive study. Increasingly, there is a focus on the prevention of hospital-acquired conditions including venous thromboembolism. Many studies have evaluated pulmonary embolism and lower extremity deep vein thrombosis, but less is known about upper extremity deep vein thrombosis (UEDVT) in hospitalized patients. The objective of this study was to describe UEDVT incidence, associated risks, outcomes, and management in our (...) in-hospital mortality. Most UEDVTs were treated even in the absence of concurrent lower extremity deep vein thrombosis or pulmonary embolism. Additional research is needed to modify risks and optimize outcomes. Journal of Hospital Medicine 2014;9:48-53. © 2013 Society of Hospital Medicine. © 2013 Society of Hospital Medicine.

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2014 Journal of Hospital Medicine

45. Postthrombotic syndrome following upper extremity deep vein thrombosis in children. (PubMed)

Postthrombotic syndrome following upper extremity deep vein thrombosis in children. Despite its relatively estimated high occurrence, the characterization of pediatric upper extremity deep vein thrombosis (UE-DVT) and of UE postthrombotic syndrome (PTS) is still lacking. We investigated the occurrence, characteristics, and predictors of UE-PTS in a cohort of children with objectively confirmed UE-DVT. Patients were analyzed in 3 groups according to DVT pathogenesis and neonatal status: primary

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2014 Blood

46. Recurrent Upper Extremity Thrombosis Associated with Overactivity: A Case of Delayed Diagnosis of Paget-Schroetter Syndrome (PubMed)

Recurrent Upper Extremity Thrombosis Associated with Overactivity: A Case of Delayed Diagnosis of Paget-Schroetter Syndrome Paget-Schroetter syndrome is thrombosis of the axillary-subclavian vein that is associated with strenuous and repetitive activity of the upper extremities. Overuse of the arm coupled with external compression results in microtrauma in the intima of the subclavian vein, resulting in the activation of the coagulation cascade. Diagnosis is usually made by Doppler ultrasound (...) and the treatment involves thrombolysis, while routine surgical decompression of the thoracic outlet is controversial. In this report, we present a case of a patient who presented with a second episode of spontaneous right upper extremity deep venous thrombosis. The first episode was inadequately treated with oral anticoagulation alone. During the second episode, Paget-Schroetter syndrome was diagnosed, after careful review of his occupational history. He subsequently underwent angioplasty and decompression

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2017 Case reports in vascular medicine

47. CRACKCast E088 – Pulmonary Embolism & Deep Venous Thrombosis

discussion) Fondaparinux Apixaban Rivaroxaban OR heparin infusion after a loading bolus Ideally transition to oral anticoagulation at least 3 months (some up to 12 months) Encourage ambulation as much as possible Bedrest promotes DVT extension, risk of embolization, and post-DVT syndrome 8) What are the common causes of upper limb DVT? Upper limb DVT = thrombosis in the axillary vein “ The deep veins of the upper extremity include the paired ulnar, radial and interosseous veins in the forearm, paired (...) of the lung that are ventilated (dead space) not being perfused. Chest pain: thought due to a focal area of lung tissue necrosis (caused by intensive inflammatory processes) Hypotension: impaired LV filling 5) What is Paget-Schroetter Syndrome? “ Effort thrombosis, or Paget-Schroetter Syndrome, refers to axillary-subclavian vein thrombosis associated with strenuous and repetitive activity of the upper extremities. Anatomical abnormalities at the thoracic outlet and repetitive trauma to the endothelium

2017 CandiEM

48. Incidence of Deep Vein Thrombosis on Central Venous Catheters in the Post Operative Period of Carcinologic Surgery

Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Thrombosis Critical Illness Venous Thrombosis Upper Extremity Deep Vein Thrombosis Embolism and Thrombosis Vascular Diseases Cardiovascular Diseases Disease Attributes Pathologic Processes (...) Incidence of Deep Vein Thrombosis on Central Venous Catheters in the Post Operative Period of Carcinologic Surgery Incidence of Deep Vein Thrombosis on Central Venous Catheters in the Post Operative Period of Carcinologic Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2017 Clinical Trials

49. Central Venous Catheter (CVC) Associated Deep Vein Thrombosis (DVT) in Cancer Patients

not have to be taken out because of the clot. Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 70 participants Observational Model: Cohort Time Perspective: Prospective Official Title: A Pilot Study in Cancer Patients With Central Venous Catheter (CVC) Associated Deep Vein Thrombosis (DVT) in the Upper Extremity Treated With Low Molecular Weight Heparin (LMWH) and Apixaban (Catheter 3) Actual Study Start Date : May 15, 2017 Estimated Primary (...) -Probability Sample Study Population Cancer patients with central venous catheter associated deep vein thrombosis in the upper extremity Criteria Inclusion Criteria: Male or female > 18 years of age. Symptomatic acute upper limb thrombosis in the axillary, subclavian or internal jugular veins, with or without pulmonary embolism, associated with central venous catheter objectively documented by compression ultrasonography, venogram or Computerized Tomography (CT) scan. Diagnosis of active malignancy

2017 Clinical Trials

50. Deep vein thrombosis after reconstructive shoulder arthroplasty: a prospective observational study. (PubMed)

Deep vein thrombosis after reconstructive shoulder arthroplasty: a prospective observational study. This clinical study was performed to document the prevalence of deep vein thrombosis (DVT) after prosthetic shoulder replacement surgery. We prospectively followed 100 consecutive shoulder arthroplasty procedures (total shoulder replacement in 73 and hemiarthroplasty in 27) in 44 male and 56 female patients for 12 weeks (mean age, 67 years; range, 17-88 years). Risk factors for venous (...) thromboembolic disease were assessed preoperatively and postoperatively. A 4-limb surveillance color flow Doppler ultrasound was performed at 2 days (100 patients) and 12 weeks (50 patients randomly selected) after surgery, and the presence and location of DVT were recorded. Postoperative symptomatic or fatal pulmonary emboli (PE) were also recorded. The overall prevalence of DVT was 13.0%, consisting of 13 DVTs in 12 patients. These included 6 ipsilateral and no contralateral upper extremity DVTs and 5

2017 Journal of Shoulder and Elbow Surgery

51. Thrombus Burden of Deep Vein Thrombosis and Its Association with Thromboprophylaxis and D-Dimer Measurement: Insights from the APEX Trial. (PubMed)

Thrombus Burden of Deep Vein Thrombosis and Its Association with Thromboprophylaxis and D-Dimer Measurement: Insights from the APEX Trial. Background The aim of this study was to evaluate the effect of betrixaban on the occurrence of deep vein thrombosis (DVT) and also the extent of thrombus and to assess the association of baseline D-dimer with subsequent thrombus burden. Methods In the APEX trial (ClinicalTrials.gov: NCT01583218), 7,513 acutely ill hospitalized medical patients were randomly (...) assigned to extended-duration betrixaban (35–42 days) or enoxaparin (10 ± 4 days). D-dimer concentration was measured at baseline, and mandatory lower-extremity compression ultrasonography (CUS) was performed at 35 to 42 days. The thrombus burden of DVT was assessed by the number of non-compressible vascular segments in six target proximal veins and compared between treatment groups and D-dimer categories (≥2 × upper limit of normal [ULN] versus <2 × ULN). Results Compared with enoxaparin, extended

2017 Thrombosis and haemostasis

52. A Case Study of Deep Vein Thrombosis of the Right Internal Jugular Vein in a Healthy 21-Year-Old Male (PubMed)

A Case Study of Deep Vein Thrombosis of the Right Internal Jugular Vein in a Healthy 21-Year-Old Male We are reporting a case of a healthy 21-year-old male, with no significant past medical history, who was found to have an incidental nonocclusive deep vein thrombosis in the right internal jugular vein detected on a head MRI previously ordered for work-up of headaches. A follow-up upper extremity venous Doppler ultrasound confirmed the presence of a partially occlusive deep vein thrombosis (...) in the right jugular vein. The case presented is unique for the reason that the patient is young and has no prior risk factor, personal or familial, for venous thrombosis except for associated polycythemia on clinical presentation.

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2016 Case reports in hematology

53. Post-thrombotic syndrome and recurrence rate in patients with primary upper extremity deep vein thrombosis: a systematic review and meta-analysis of proportions

Post-thrombotic syndrome and recurrence rate in patients with primary upper extremity deep vein thrombosis: a systematic review and meta-analysis of proportions Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr

2017 PROSPERO

54. Upper Extremity DVT versus Lower Extremity DVT: Perspectives from the GARFIELD-VTE Registry. (PubMed)

Upper Extremity DVT versus Lower Extremity DVT: Perspectives from the GARFIELD-VTE Registry. Upper extremity deep vein thrombosis (UEDVT) is less common than lower extremity DVT (LEDVT) and consequently less well characterized. This study compared clinical characteristics and 1-year outcomes between 438 UEDVT patients and 7,602 LEDVT patients recruited in the GARFIELD-VTE registry. UEDVT patients were significantly more likely to have a central venous catheter than those with LEDVT (11.5% vs

2019 Thrombosis and haemostasis

55. Current management strategies and long-term clinical outcomes of upper extremity venous thrombosis. (PubMed)

Current management strategies and long-term clinical outcomes of upper extremity venous thrombosis. Essentials Few data exist on outcome of upper extremity deep and superficial vein thrombosis (UEDVT and UESVT). We followed 102 and 55 patients with UEDVT or UESVT, respectively, for a median of 3.5 years. Risk of recurrent venous thromboembolism was low in both diseases, and the mortality high. Postthrombotic symptoms were infrequent and cancer patients had a higher risk of recurrent (...) VTE.Background There is scant information on the optimal management and clinical outcome of deep and superficial vein thrombosis of the upper extremity (UEDVT and UESVT). Objectives To explore treatment strategies and the incidence of recurrent venous thromboembolism (VTE), mortality, postthrombotic symptoms, and bleeding in patients with UEDVT and UESVT and to assess the prognosis of cancer patients with UEDVT. Patients/methods Follow-up of patients with UEDVT or UESVT, who were enrolled previously

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2016 Journal of Thrombosis and Haemostasis

56. High risk of deep vein thrombosis associated with peripherally inserted central catheters in lymphoma (PubMed)

thrombosis in lymphoma compared with its incidences in other types of cancer. A total of 8028 adult cancer patients inserted with PICC between June 2007 and June 2015 were included in this study. A total of 249 of the 8028 included patients (3.1%) inserted with PICC developed upper extremity deep vein thrombosis (PICC-UEDVT). Patients with lymphoma were more likely to have PICC-UEDVT than those with other types of malignancies (7.1% vs. 2.80%; P < 0.001). Logistic analysis revealed that a lymphoma (...) High risk of deep vein thrombosis associated with peripherally inserted central catheters in lymphoma Peripherally inserted central venous catheters (PICCs) are widely used in cancer patients. Although PICC is a convenient tool, its use is associated with an obvious increase in the incidence of venous thrombosis. The risk factors for deep vein thrombosis associated with the use of PICCs in cancer patients are largely unexplored. This study aimed to investigate the incidence of PICC-associated

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2016 Oncotarget

57. Deep Vein Thrombosis

-thrombotic syndrome: >50% Venous at 5 years in nearly half of patients Efficacy data (some studies question longterm benefit) Normal vein after Catheter : 45% (contrast with 0% after alone) Decreases risk of long term , post-phlebitic syndrome, stasis ulcers Best outcome if performed early (within 2 weeks) Poor efficacy if prior Deep Vein Thrombosis References Other indications Massive proximal extremity DVT with severe symptoms or XII. Complications Post-thrombotic syndrome (postphlebitic syndrome (...) -GLOSS) The formation of a blood clot in a deep vein of the leg or lower pelvis. Symptoms may include pain, swelling, warmth, and redness in the affected area. Definition (NCI) A blood clot in a deep vein, predominantly in the lower extremity, but may include the pelvis or upper extremity.(NICHD) Definition (NCI_CDISC) A blood clot (thrombus) in a deep vein in the lower extremity. Concepts Disease or Syndrome ( T047 ) MSH ICD10 SnomedCT 128053003 , 128057002 , 195403006 , 266328001 , 155454004 LNC

2018 FP Notebook

58. Apixaban for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolism

with apixaban compared with rivaroxaban. Apixaban for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolism (TA341) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 12 of 40However, the ERG was satisfied that the company's analyses provided in response to clarification resulted in less extreme estimates of the underlying treatment effect (that is, they were less likely to over (...) Apixaban for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolism Apixaban for the treatment and Apixaban for the treatment and secondary pre secondary prev vention of deep v ention of deep vein ein thrombosis and/or pulmonary embolism thrombosis and/or pulmonary embolism T echnology appraisal guidance Published: 4 June 2015 nice.org.uk/guidance/ta341 © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions

2015 National Institute for Health and Clinical Excellence - Technology Appraisals

59. Deep Vein Thrombosis and Pulmonary Embolism in Liver Transplant Patients: Risks and Prevention (PubMed)

Deep Vein Thrombosis and Pulmonary Embolism in Liver Transplant Patients: Risks and Prevention Deep vein thrombosis (DVT) and pulmonary embolism (PE) are surgical complications estimated to occur in 5% to 10% of patients. There are limited data regarding DVT/PE in the early postoperative period in liver transplant patients. The aim of this study is to determine risk factors that influence the incidence of DVT/PE and the effectiveness of prophylaxis.We reviewed the records of 999 patients who (...) underwent initial liver transplant between January 2000 and June 2012 at Henry Ford Hospital. In 2011, a standardized prophylactic regimen using subcutaneous (SQ) heparin was initiated. All patients that developed either upper/lower extremity DVT or PE within the first 30 days of transplant formed the cohort of this study.On multivariate analysis, only peripherally inserted central catheter (PICC) placement and SQ heparin were associated with DVT/PE. In patients receiving heparin, 3 (1.0%) had DVT/PE

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2016 Transplantation direct

60. Postoperative Massive Pulmonary Embolism Due to Superficial Vein Thrombosis of the Upper Limb (PubMed)

Postoperative Massive Pulmonary Embolism Due to Superficial Vein Thrombosis of the Upper Limb It is well known that deep vein thrombosis of the upper extremities is linked to high morbidity/mortality, resulting in 12-20% of all documented pulmonary embolism; however, there are few data about thromboembolism originating from a vein and/or a branch of a superficial vein of the upper extremities. Pulmonary embolism secondary to upper limb superficial vein thrombosis (not combined with upper (...) extremities deep vein thrombosis) is a very rare clinical manifestation with few cases reported in the literature. We report a rare case of thrombophlebitis in departure from a superficial branch of the cephalic vein of the right arm, complicated by cardiac arrest secondary to a massive pulmonary embolism in a patient who underwent major surgery for ovarian cancer. We discuss on the numerous thrombotic risk factors, triggering a cascade of reactions and resulting in a potential fatal clinical

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2016 Journal of clinical medicine research

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