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Deep Vein Thrombosis Probability

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1. Graduated compression stockings for prevention of deep vein thrombosis. (PubMed)

Graduated compression stockings for prevention of deep vein thrombosis. Hospitalised patients are at increased risk of developing deep vein thrombosis (DVT) in the lower limb and pelvic veins, on a background of prolonged immobilisation associated with their medical or surgical illness. Patients with DVT are at increased risk of developing a pulmonary embolism (PE). The use of graduated compression stockings (GCS) in hospitalised patients has been proposed to decrease the risk of DVT (...) . This is an update of a Cochrane Review first published in 2000, and last updated in 2014.To evaluate the effectiveness and safety of graduated compression stockings in preventing deep vein thrombosis in various groups of hospitalised patients.For this review the Cochrane Vascular Information Specialist searched the Cochrane Vascular Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL), and trials registries on 21 March 2017; and the Cochrane Vascular Specialised Register, CENTRAL

2018 Cochrane

2. Blood and Clots Series: How can I tell whether this patient has a deep vein thrombosis?

with increasing pain and edema in his left leg. In a recent hospital admission he was diagnosed with myeloma. This case reviews pretest probability of deep vein thrombosis, D-dimer and interpretation of compression ultrasound. Main Text Last week when I came onto a day shift I was handed over a patient who was waiting for an ultrasound scan. He was a 65 year old man who presented at midnight to the emergency department, 6 days after being discharged from hospital. He was diagnosed with multiple myeloma during (...) . There was no tenderness in the distribution of the deep calf veins although he was tender in the medial mid-thigh. There were no other signs of deep vein thrombosis (DVT). Clinical probability estimation No diagnostic test is either 100% sensitive or 100% specific. As physicians, we can’t diagnose or exclude a condition without considering the results within the clinical context of our individual patient. This is Bayes theorem, which uses the pretest probability of a condition to calculate the probability

2018 CandiEM

3. Deep Vein Thrombosis: Diagnosis

of DVT presence [see Deep Vein Thrombosis (DVT): Treatment guide]. The accurate exclusion of DVT also eliminates unnecessary exposure to anticoagulants, associated with inconvenience and risk of bleeding. DIAGNOSIS: The diagnosis of DVT is based on: 1) Pre-test probability (clinical suspicion) There are several formal risk models available to assess the pre-test probability of DVT. The Wells Score is the most widely used (see Table 1). Physicians can also use their clinical gestalt to determine pre (...) -test probability. The accuracy of this type of intuitive approach, however, is dependent on physician experience. Use of a structured score is encouraged. TABLE 1: TWO-LEVEL WELLS SCORE FOR DVT DIAGNOSIS CLINICAL FINDINGS POINTS Paralysis, paresis or recent orthopedic casting of lower extremity 1 Bedridden >3 days recently or major surgery within past 12 weeks 1 Localized tenderness of the deep veins 1 © 2016 Thrombosis Canada Page 2 of 6 Swelling of entire leg 1 Calf swelling 3 cm greater than

2016 Thrombosis Interest Group of Canada

4. Diagnosis and management of iliofemoral deep vein thrombosis: clinical practice guideline

Diagnosis and management of iliofemoral deep vein thrombosis: clinical practice guideline Guidelines CMAJ ©2015 8872147 Canada Inc. or its licensors CMAJ 1 CME V enous thromboembolism, presenting as deep vein thrombosis (DVT) or pul- monary embolism, affects over 35 000 Canadians each year. 1 It is associated with substantial morbidity, mortality and burden on the Canadian health care system, with one- month mortality rates estimated at 6% for DVT and 12% for pulmonary embolism. 1 Iliofemoral (...) Association clinical practice method- ology 17 (Box 1) to classify the recommenda- tions and levels of evidence and translated these to the corresponding GRADE strengths of rec- ommendations and confidence in effect esti - mates (Box 2). 17–20 We applied the Appraisal of Guidelines for Research and Evaluation (AGREE II) appraisal tools for clinical practice guidelines. 21,22 Diagnosis and management of iliofemoral deep vein thrombosis: clinical practice guideline David Liu MD, Erica Peterson MD MSc, James

2015 CPG Infobase

5. Early mobilization versus bed rest for deep vein thrombosis. (Full text)

a summary of findings table following the GRADE approach. We concluded early ambulation is probably effective in reducing deep vein thrombosis progression and improving limb pain, and might not increase the risk of thromboembolism. (...) Early mobilization versus bed rest for deep vein thrombosis. Aiming to prevent thromboembolic events, bed rest was historically considered in the management of patient with deep vein thrombosis. Nevertheless early ambulation could have beneficial effects. Searching in Epistemonikos database, which is maintained by screening 30 databases, we identified seven systematic reviews including 10 randomized trials answering this question. We combined the evidence using meta-analysis and generated

2017 Medwave PubMed

6. Deep Vein Thrombosis Probability

Deep Vein Thrombosis Probability Deep Vein Thrombosis Probability Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Deep Vein Thrombosis (...) Probability Deep Vein Thrombosis Probability Aka: Deep Vein Thrombosis Probability , DVT Probability , Wells Clinical Prediction Rule for DVT II. Indications Assess DVT Pretest Probability III. Criteria Active malignancy within last six months: 1 point Lower extremity immobility: 1 point Cast Paralysis Restricted mobility within last 4 weeks: 1 point Bedridden for more than 3 days Major surgery Localized pain over deep venous course: 1 point Calf circumference 3 cm over opposite calf: 1 point Measure 10

2018 FP Notebook

7. Proximal and isolated distal deep vein thrombosis and Wells score accuracy in hospitalized patients. (PubMed)

Proximal and isolated distal deep vein thrombosis and Wells score accuracy in hospitalized patients. Deep vein thrombosis (DVT) is an important cause of morbidity and mortality in hospitalized patients. The Wells score for DVT pretest probability (PTP) was validated in outpatients, but its utility for inpatients is unclear. The aim of this study was to establish the prevalence of inpatient proximal and distal DVT and the Wells score performance in inpatients. A single-center cross-sectional

2019 Internal and emergency medicine

8. Changing Patterns of Anticoagulation After Total Hip Arthroplasty in the United States: Frequency of Deep Vein Thrombosis, Pulmonary Embolism, and Complications With Rivaroxaban and Warfarin. (PubMed)

THA were followed for use of anticoagulants after surgery. Logistic regression models were used to compare differences in deep vein thrombosis (DVT), pulmonary embolism (PE), and adverse events, within 90 days after THA, among warfarin and rivaroxaban users. Inverse probability treatment weighting was used to account for selection bias.There were 12,876 users of warfarin and 10,892 users of rivaroxaban in commercially insured (CI) patients, and 7416 warfarin users and 4739 rivaroxaban users (...) Changing Patterns of Anticoagulation After Total Hip Arthroplasty in the United States: Frequency of Deep Vein Thrombosis, Pulmonary Embolism, and Complications With Rivaroxaban and Warfarin. This study evaluated the trends in anticoagulation use after total hip arthroplasty (THA), and the effectiveness and safety of rivaroxaban compared to warfarin.This retrospective database analysis used healthcare claims from the Truven Health MarketScan database (2010-2015). Patients undergoing elective

2019 Journal of Arthroplasty

9. Deep vein thrombosis: update on diagnosis and management. (PubMed)

Deep vein thrombosis: update on diagnosis and management. Diagnosis of deep vein thrombosis (DVT) requires a multifaceted approach that includes clinical assessment, evaluation of pre-test probability, and objective diagnostic testing. Common symptoms and signs of DVT are pain, swelling, erythema and dilated veins in the affected limb. The pre-test probability of DVT can be assessed using a clinical decision rule that stratifies DVT into "unlikely" or "likely". If DVT is "unlikely", refer for D

2019 Medical Journal of Australia

10. Probability of developing proximal deep-vein thrombosis and/or pulmonary embolism after distal deep-vein thrombosis. (PubMed)

Probability of developing proximal deep-vein thrombosis and/or pulmonary embolism after distal deep-vein thrombosis. Isolated distal deep-vein thrombosis (DDVT) of the lower extremities can be associated with subsequent proximal deep-vein thrombosis (PDVT) and/or acute pulmonary embolism (PE). We aimed to develop a model predicting the probability of developing PDVT and/or PE within three months after an isolated episode of DDVT. We conducted a retrospective cohort study of patients (...) with symptomatic DDVT confirmed by lower extremity vein ultrasounds between 2001-2012 in the Cleveland Clinic Health System. We reviewed all the ultrasounds, chest ventilation/perfusion and computed tomography scans ordered within three months after the initial DDVT to determine the incidence of PDVT and/or PE. A multiple logistic regression model was built to predict the rate of developing these complications. The final model included 450 patients with isolated DDVT. Within three months, 30 (7 %) patients

2015 Thrombosis and haemostasis

11. Assessment of the Probability of Post-thrombotic Syndrome in Patients with Lower Extremity Deep Venous Thrombosis (Full text)

Assessment of the Probability of Post-thrombotic Syndrome in Patients with Lower Extremity Deep Venous Thrombosis This study was performed to assess the probability of post-thrombotic syndrome (PTS) after treatment of lower extremity deep venous thrombosis (LEDVT). Patients with LEDVT undergoing their first treatments in Nanjing First Hospital from January 2013 to December 2014 were enrolled in this study (156 patients were enrolled in the training cohort, and 135 patients were enrolled (...) in the validation cohort). 51 and 45 patients developed PTS in the two cohorts, respectively. Independent risk factors for PTS were investigated in the training cohort, and these independent risk factors were employed to develop the APTSD scoring system with which to predict the probability of PTS. Four independent risk factors for PTS were identified: iliac vein compression syndrome, residual iliac-femoral vein thrombosis, residual femoral-popliteal vein thrombosis and insufficient anticoagulation. Patients

2018 Scientific reports PubMed

12. The use of age-related D-dimers to rule out deep vein thrombosis

in patients with low clinical probability without the need for ultrasound scanning. References Schouten HJ, Koek HL, Oudega R et al. Validation of two age dependent D-dimer cut-off values for exclusion of deep vein thrombosis in suspected elderly patients in primary care: retrospective, cross sectional, diagnostic analysis. BMJ 2012, Vol. 344:e2985 Douma RA, Tan M, Schutgens REG et al. Using an age-dependent D-dimer cut-off value increases the number of older patients in whom deep vein thrombosis can (...) The use of age-related D-dimers to rule out deep vein thrombosis BestBets: The use of age-related D-dimers to rule out deep vein thrombosis The use of age-related D-dimers to rule out deep vein thrombosis Report By: Catherine Taylor - Medical Student Search checked by Laith Sultan - Consultant in Emergency Medicine Institution: University of Manchester, University Hospital South Manchester, Manchester, UK Date Submitted: 17th August 2014 Date Completed: 26th August 2015 Last Modified: 26th

2015 BestBETS

13. Prediction rule: Low failure rate reported of diagnosis algorithm for suspected upper extremity deep vein thrombosis

algorithm for suspected upper extremity deep vein thrombosis Aurelien Delluc , Philip S Wells Statistics from Altmetric.com Commentary on: Kleinjan A , Di Nisio M , Beyer-Westendorf J , et al . Safety and feasibility of a diagnostic algorithm combining clinical probability, d-dimer testing and ultrasonography for suspected upper extremity deep venous thrombosis: a prospective management study . Context Upper extremity deep vein thrombosis (UEDVT) is an infrequent type of venous thromboembolism (...) Prediction rule: Low failure rate reported of diagnosis algorithm for suspected upper extremity deep vein thrombosis Low failure rate reported of diagnosis algorithm for suspected upper extremity deep vein thrombosis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password

2014 Evidence-Based Medicine (Requires free registration)

14. Quality Improvement Guidelines for the Treatment of Lower-Extremity Deep Vein Thrombosis with Use of Endovascular Thrombus Removal

Quality Improvement Guidelines for the Treatment of Lower-Extremity Deep Vein Thrombosis with Use of Endovascular Thrombus Removal STANDARDS OF PRACTICE Quality Improvement Guidelines for the Treatment of Lower-Extremity Deep Vein Thrombosis with Use of Endovascular Thrombus Removal Suresh Vedantham, MD, Akhilesh K. Sista, MD, Seth J. Klein, MD, Lina Nayak, MD, Mahmood K. Razavi, MD, Sanjeeva P. Kalva, MD, Wael E. Saad, MD, Sean R. Dariushnia, MD, Drew M. Caplin, MD, Christine P. Chao, MD (...) by telephone conference calling or face- to-face meeting. The ?nalized draft from the Committee is sent to the SIR membership for further input/criticism during a 30-day comment period. These comments are discussed by the Standards of Practice Committee, and appropriate revisions are made to create the ?nished standards document. Before its publication, the document is endorsed by the SIR Executive Council. INTRODUCTION Lower-extremity deep vein thrombosis (DVT) is a serious medical condition that can

2014 Society of Interventional Radiology

15. Impact of medication adherence on risk of ischemic stroke, major bleeding, and deep vein thrombosis in atrial fibrillation patients using novel oral anticoagulants. (PubMed)

Impact of medication adherence on risk of ischemic stroke, major bleeding, and deep vein thrombosis in atrial fibrillation patients using novel oral anticoagulants. Our study examined the impact of adherence to novel oral anticoagulants [NOACs - dabigatran and rivaroxaban] on ischemic-stroke (IS), major-bleeding (MB), deep-vein-thrombosis and pulmonary-embolism (DVTPE) risk in a large, nationwide, propensity-matched sample.A retrospective cohort study utilized data from a US commercial managed (...) -care database (2010-2012). Adult patients with ≥1 diagnosis of atrial fibrillation/flutter (ICD-9 427.31/32), >1 prescription of NOACs and CHA2DS2-VASc score ≥1 were included. Patients were categorized as adherent versus nonadherent (using proportion of days covered [PDC ≥80%]) based on their NOAC use up to 6 months and those continued its use up to 12 months. The patients were matched using propensity score (based on inverse probability treatment weighting) and the risk of IS, MB, DVTPE outcomes

2018 Current medical research and opinion

16. Primary Upper Limb Deep Vein Thrombosis. Is First Rib Resection Necessary?

Primary Upper Limb Deep Vein Thrombosis. Is First Rib Resection Necessary? Primary Upper Limb Deep Vein Thrombosis. Is First Rib Resection Necessary? - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Primary (...) Upper Limb Deep Vein Thrombosis. Is First Rib Resection Necessary? The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03547921 Recruitment Status : Not yet recruiting First Posted : June 6, 2018 Last Update Posted : June 6

2018 Clinical Trials

17. Validation of the STA-Liatest DDi assay for exclusion of proximal deep vein thrombosis according to the latest Clinical and Laboratory Standards Institute/Food and Drug Administration guideline: results of a multicenter management study (Full text)

Validation of the STA-Liatest DDi assay for exclusion of proximal deep vein thrombosis according to the latest Clinical and Laboratory Standards Institute/Food and Drug Administration guideline: results of a multicenter management study : Recommended strategy for venous thromboembolism (VTE) diagnosis includes the use of sensitive D-dimer (DDi) assays along with pretest probability (PTP) assessment. The Clinical and Laboratory Standards Institute (CLSI) recently issued a guideline (US FDA (...) endorsed) on DDi in VTE exclusion. Such guideline specifies the ideal D-dimer assay characteristics and target population. Demonstrate STA-LiatestD-Di performance combined with a PTP score for proximal deep vein thrombosis (pDVT) exclusion in a CLSI compliant study. International, multicenter, prospective nonrandomized, noninterventional clinical outcome management study conducted in a standard-of-care setting. DDi was measured in DVT-suspected consecutive low/moderate PTP outpatients, without

2018 Blood Coagulation & Fibrinolysis PubMed

18. Incidence of deep vein thrombosis before and after total knee arthroplasty without pharmacologic prophylaxis: a 128-row multidetector CT indirect venography study. (Full text)

Incidence of deep vein thrombosis before and after total knee arthroplasty without pharmacologic prophylaxis: a 128-row multidetector CT indirect venography study. We sought to document the incidences of deep vein thrombosis (DVT) before and after total knee arthroplasty (TKA). In addition, we aimed to explor whether routine preoperative DVT evaluation was useful to establish DVT treatment strategies after TKA. Finally, we wanted to evaluate whether the incidences of DVT differed between (...) DVTs were distal in nature and asymptomatic. After TKA, newly developed thrombi were evident in various calf veins, without propagation of any pre-existing thrombi. Postoperatively, the overall incidences of DVT were 69.9% per patient and 58.5% per knee. The DVT incidences were 66% per patient and 69.8% per knee in the unilateral TKA group. In contrast, the incidences were 72% per patient and 55.5% per knee in the staged bilateral TKA group. There was one case of symptomatic distal (unilateral TKA

2018 BMC Musculoskeletal Disorders PubMed

19. Prevalence of Post-Thrombotic Syndrome in Deep-Vein Thrombosis (DVT) Patients Treated With Dabigatran

Prevalence of Post-Thrombotic Syndrome in Deep-Vein Thrombosis (DVT) Patients Treated With Dabigatran Prevalence of Post-Thrombotic Syndrome in Deep-Vein Thrombosis (DVT) Patients Treated With Dabigatran - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Prevalence of Post-Thrombotic Syndrome in Deep-Vein Thrombosis (DVT) Patients Treated With Dabigatran (DABI-PTS) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03050138

2017 Clinical Trials

20. Age-adjusted D-dimer to rule out deep vein thrombosis: findings from the PALLADIO algorithm. (Full text)

been proposed to increase specificity for the diagnosis of venous thromboembolism (VTE). However, the accuracy of this threshold has been recently questioned. Objectives To assess the diagnostic performance of age-adjusted D-dimer combined with clinical pretest probability (PTP) in patients with suspected deep vein thrombosis (DVT). Methods PALLADIO (NCT01412242) was a multicenter management study that validated a new diagnostic algorithm, incorporating PTP, D-dimer (using the manufacturer's cut (...) Age-adjusted D-dimer to rule out deep vein thrombosis: findings from the PALLADIO algorithm. Essentials The accuracy of the age-adjusted D-dimer in suspected venous thromboembolism is still debated. We assessed the performance of age-adjusted D-dimer combined with the PALLADIO algorithm. The age-adjusted threshold can reduce the need for imaging tests compared to the fixed cut-off. The safety of this approach should be confirmed in large management studies.Background Age-adjusted D-dimer has

2017 Journal of Thrombosis and Haemostasis PubMed

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