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Deep Vein Thrombosis Prevention

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1. Graduated compression stockings for prevention of deep vein thrombosis. (PubMed)

Graduated compression stockings for prevention of deep vein thrombosis. Hospitalised patients are at increased risk of developing deep vein thrombosis (DVT) in the lower limb and pelvic veins, on a background of prolonged immobilisation associated with their medical or surgical illness. Patients with DVT are at increased risk of developing a pulmonary embolism (PE). The use of graduated compression stockings (GCS) in hospitalised patients has been proposed to decrease the risk of DVT (...) . This is an update of a Cochrane Review first published in 2000, and last updated in 2014.To evaluate the effectiveness and safety of graduated compression stockings in preventing deep vein thrombosis in various groups of hospitalised patients.For this review the Cochrane Vascular Information Specialist searched the Cochrane Vascular Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL), and trials registries on 21 March 2017; and the Cochrane Vascular Specialised Register, CENTRAL

2018 Cochrane

2. Percutaneous mechanical thrombectomy for acute deep vein thrombosis of the leg

Percutaneous mechanical thrombectomy for acute deep vein thrombosis of the leg P Percutaneous mechanical thrombectom ercutaneous mechanical thrombectomy for y for acute deep v acute deep vein thrombosis of the leg ein thrombosis of the leg Interventional procedures guidance Published: 12 June 2019 www.nice.org.uk/guidance/ipg651 Y Y our responsibility our responsibility This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising (...) mechanical thrombectomy for acute deep vein thrombosis (DVT) of the leg shows there are well-recognised but infrequent complications. © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 1 of 5For acute iliofemoral DVT the evidence on efficacy is limited in quality and quantity, therefore this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. For distal DVT

2019 National Institute for Health and Clinical Excellence - Interventional Procedures

3. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism

dabigatran etexilate for the prevention of venous thromboembolism after hip or knee replacement surgery in adults (NICE technology appraisal guidance 157).] [2018] [2018] Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism (NG89) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 17 of 411.11.7 Consider anti-embolism stockings until discharge from hospital (...) is from dabigatran etexilate for the prevention of venous thromboembolism after hip or knee replacement surgery in adults (NICE technology appraisal guidance 157).] [2018] [2018] 1.11.10 Consider intermittent pneumatic compression if pharmacological prophylaxis is contraindicated in people undergoing elective knee replacement surgery. Continue until the person is mobile. [2018] [2018] Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

4. Compression stockings for preventing deep vein thrombosis in airline passengers. (PubMed)

Compression stockings for preventing deep vein thrombosis in airline passengers. Air travel might increase the risk of deep vein thrombosis (DVT). It has been suggested that wearing compression stockings might reduce this risk. This is an update of the review first published in 2006.To assess the effects of wearing compression stockings versus not wearing them for preventing DVT in people travelling on flights lasting at least four hours.For this update the Cochrane Vascular Information (...) -quality evidence). There were no symptomless DVTs in three trials. Sixteen of 1804 people developed superficial vein thrombosis, four wore stockings, 12 did not (OR 0.45, 95% CI 0.18 to 1.13, P = 0.09; moderate-quality evidence). No deaths, pulmonary emboli or symptomatic DVTs were reported. Wearing stockings had a significant impact in reducing oedema (mean difference (MD) -4.72, 95% CI -4.91 to -4.52; based on six trials; low-quality evidence). A further two trials showed reduced oedema

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2016 Cochrane

5. Deep vein thrombosis

Deep vein thrombosis Deep vein thrombosis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Deep vein thrombosis Last reviewed: February 2019 Last updated: November 2018 Summary Patients who develop deep vein thrombosis (DVT) commonly have thromboembolic risk factors, such as cancer, trauma, major surgery, hospitalisation, immobilisation, pregnancy, or oral contraceptive use. However, many patients have no history (...) weight heparin, fondaparinux, rivaroxaban, apixaban, edoxaban, dabigatran, and/or warfarin. Generally, oral anticoagulation is continued for 3 to 6 months. In selected patients with significant thromboembolic risks, careful consideration should be given to maintaining oral anticoagulation indefinitely as long as the risks of bleeding are lower than the risks of recurrent venous thrombosis. Definition Deep vein thrombosis (DVT) is the development of a blood clot in a major deep vein in the leg, thigh

2018 BMJ Best Practice

6. Deep vein thrombosis

Deep vein thrombosis Deep vein thrombosis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Deep vein thrombosis Last reviewed: February 2019 Last updated: November 2018 Summary Patients who develop deep vein thrombosis (DVT) commonly have thromboembolic risk factors, such as cancer, trauma, major surgery, hospitalisation, immobilisation, pregnancy, or oral contraceptive use. However, many patients have no history (...) weight heparin, fondaparinux, rivaroxaban, apixaban, edoxaban, dabigatran, and/or warfarin. Generally, oral anticoagulation is continued for 3 to 6 months. In selected patients with significant thromboembolic risks, careful consideration should be given to maintaining oral anticoagulation indefinitely as long as the risks of bleeding are lower than the risks of recurrent venous thrombosis. Definition Deep vein thrombosis (DVT) is the development of a blood clot in a major deep vein in the leg, thigh

2018 BMJ Best Practice

7. Suspected Upper-Extremity Deep Vein Thrombosis.

Suspected Upper-Extremity Deep Vein Thrombosis. Date of origin: 1995 Last review date: 2014 ACR Appropriateness Criteria ® 1 Upper Extremity Swelling American College of Radiology ACR Appropriateness Criteria ® Clinical Condition: Upper Extremity Swelling Radiologic Procedure Rating Comments RRL* US duplex Doppler upper extremity 9 This procedure is standard for arm veins. Other modalities are required for evaluating central veins. O X-ray chest 8 This procedure is a simple evaluation of lines (...) in these procedures vary as a function of a number of factors (eg, region of the body exposed to ionizing radiation, the imaging guidance that is used). The RRLs for these examinations are designated as “Varies”. Supporting Documents For additional information on the Appropriateness Criteria methodology and other supporting documents go to www.acr.org/ac. References 1. Joffe HV, Kucher N, Tapson VF, Goldhaber SZ. Upper-extremity deep vein thrombosis: a prospective registry of 592 patients. Circulation. 2004;110

2019 American College of Radiology

8. Graduated compression stockings for the prevention of deep-vein thrombosis in postoperative surgical patients: a systematic review and economic model with a value of information analysis

Graduated compression stockings for the prevention of deep-vein thrombosis in postoperative surgical patients: a systematic review and economic model with a value of information analysis Graduated compression stockings for the prevention of deep vein thrombosis in postoperative surgical patients; a systematic review and economic model with a value of information analysis Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found

2015 NIHR HTA programme

9. A Systematic Review on the Use of Aspirin in the Prevention of Deep Vein Thrombosis in Major Elective Lower Limb Orthopedic Surgery: An Update from the Past 3 Years. (PubMed)

A Systematic Review on the Use of Aspirin in the Prevention of Deep Vein Thrombosis in Major Elective Lower Limb Orthopedic Surgery: An Update from the Past 3 Years. Introduction  Currently there are no consensuses in the national guidance on thromboprophylaxis following major elective lower limb surgery. Emerging clinical evidence suggests that aspirin could be just as effective as anticoagulants with a lower cost. The aim of this study was to provide an update based on literature of the past (...) 3 years for the use of aspirin as thromboprophylaxis after knee and hip arthroplasty. Materials and Methods  MEDLINE/EMBASE search was performed with appropriate terms for original articles from 2014 to 2017. Results  Eight articles were found. Five articles concluded that aspirin was an effective prophylactic. The collation of results on the deep vein thrombosis rate involved 43,012 patients who were prescribed aspirin, of which 283 (0.66%) suffered from symptomatic deep vein thromboses

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2018 Surgery journal (New York, N.Y.)

10. Graduated compression stockings for prevention of deep vein thrombosis. (PubMed)

Graduated compression stockings for prevention of deep vein thrombosis. One of the settings where deep vein thrombosis (DVT) in the lower limb and pelvic veins occurs is in hospital with prolonged immobilisation of patients for various surgical and medical illnesses. Using graduated compression stockings (GCS) in these patients has been proposed to decrease the risk of DVT. This is an update of a Cochrane review first published in 2000 and updated in 2010.To evaluate the effectiveness (...) and safety of graduated compression stockings in preventing DVT in various groups of hospitalised patients.For this update the Cochrane Peripheral Vascular Diseases Group Trials Search Co-ordinator searched the Specialised Register (last searched March 2014) and CENTRAL (2014, Issue 2).Randomised controlled trials (RCTs) involving GCS alone; or GCS used on a background of any other DVT prophylactic method. Results from both these groups of trials were combined in this update.For this update one review

2014 Cochrane

11. Pharmacomechanical thrombectomy for iliofemoral deep vein thrombosis. (PubMed)

Pharmacomechanical thrombectomy for iliofemoral deep vein thrombosis. Deep venous thrombosis (DVT) occurs in approximately one in 1000 adults every year, and has an annual mortality of 14.6%. In particular, iliofemoral DVT can lead to recurrent thrombosis and post-thrombotic syndrome (PTS), a painful condition which can lead to chronic venous insufficiency, oedema, and ulceration. It causes significant disability, impaired quality of life, and economic burden. Early thrombus removal techniques (...) patients with an iliofemoral deep vein thrombosis were allocated to receive pharmacomechanical thrombectomy versus anticoagulation, mechanical thrombectomy, thrombolysis (systemic or catheter directed thrombolysis), or other endovascular techniques for the treatment of iliofemoral DVT.At least two review authors independently assessed studies identified for potential inclusion.We found no randomised controlled trials that met the eligibility criteria for this review. We identified one ongoing

2016 Cochrane

12. Thrombolysis may reduce complications of deep vein thrombosis

is the use of anticoagulants or blood thinners. Up to half of patients develop post-thrombotic syndrome. Compression stockings were claimed to prevent post-thrombotic syndrome but recent studies do not support their use. The use of thrombolysis or clot dissolving drugs provides a further option in selected patients. This approach might reduce this syndrome but at the cost of increased bleeding. The role of thrombolysis in treatment of acute deep vein thrombosis requires clarification. Roopen Arya (...) Thrombolysis may reduce complications of deep vein thrombosis Thrombolysis may reduce complications of deep vein thrombosis Discover Portal Discover Portal Thrombolysis may reduce complications of deep vein thrombosis Published on 18 April 2017 doi: Blood clots are cleared quickly for people who develop them in the deep leg veins if they receive thrombolysis drugs alongside other treatments directly into their veins. The chance of successful break down of the clot was compared with the chance

2019 NIHR Dissemination Centre

13. Deep Vein Thrombosis: Diagnosis

the next 3-7 days. Depending on local availability and expertise, MRI can be used to confirm abnormalities restricted to the iliac vein. OTHER RELEVANT THROMBOSIS CANADA CLINICAL GUIDES: ? Central Venous Catheter-Related Venous Thrombosis ? Deep Venous Thrombosis (DVT): Treatment ? Diagnosis of DVT and PE in Pregnancy ? Pediatric Thrombosis ? Pulmonary Embolism (PE): Diagnosis REFERENCES: Bates SM, et al. Diagnosis of DVT: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College (...) Deep Vein Thrombosis: Diagnosis © 2016 Thrombosis Canada Page 1 of 6 DEEP VEIN THROMBOSIS (DVT): DIAGNOSIS OBJECTIVE: To provide an evidenced-based approach to the evaluation of patients with a clinical suspicion of deep vein thrombosis (DVT). BACKGROUND: An estimated 45,000 patients in Canada are affected by DVT each year, with an incidence of approximately 1-2 cases per 1,000 persons annually. This translates into 2-4 DVTs per year in a typical, solo Canadian family practice. Since only 10-20

2016 Thrombosis Interest Group of Canada

14. Lixiana (edoxaban) - for the prevention of embolism in patients with nonvalvular atrial fibrillation OR treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) and prevention of recurrent DVT and PE.

Lixiana (edoxaban) - for the prevention of embolism in patients with nonvalvular atrial fibrillation OR treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) and prevention of recurrent DVT and PE. Lixiana (edoxaban) × Insert searchphrase to search the website Insert searchphrase to search the website > > > Lixiana (edoxaban) Conclusion Lixiana (edoxaban) is the fourth Non-vitamin K Oral Anticoagulant (NOAC) in Denmark after Eliques (apixaban), Xarelto (rivaroxaban) and Pradaxa (...) (dabigatran). Lixiana is indicated for the prevention of embolism in patients with nonvalvular atrial fibrillation (NVAF) with one or more risk factors and treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) and prevention of recurrent DVT and PE. For either indication, Lixiana is not inferior to warfarin when it comes to preventing embolism and has a statistically significantly lower occurrence of major bleeding. The lower risk of bleeding is particularly evident in comparisons

2017 Danish Pharmacotherapy Reviews

15. Percutaneous mechanical thrombectomy for deep vein thrombosis

Percutaneous mechanical thrombectomy for deep vein thrombosis Percutaneous mechanical thrombectomy for deep vein thrombosis Percutaneous mechanical thrombectomy for deep vein thrombosis HAYES, Inc. Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc.. Percutaneous mechanical thrombectomy for deep vein thrombosis. Lansdale: HAYES, Inc.. Directory (...) Publication. 2016 Authors' conclusions Percutaneous mechanical thrombectomy (PMT) involves the mechanical removal of a thrombus or embolism from the vascular system using percutaneous access. PMT devices utilize various mechanisms to disrupt and remove thromboembolisms, including rheolytic, rotational, and ultrasound-assisted systems. PMT is often used in concert with local application of thrombolytic drugs. The objectives of using PMT to treat a patient with deep vein thrombosis (DVT) are to remove

2016 Health Technology Assessment (HTA) Database.

16. Low-molecular weight heparins versus warfarin for the long-term prevention or treatment of deep vein thrombosis or pulmonary embolism: a review of the clinical and cost-effectiveness

Low-molecular weight heparins versus warfarin for the long-term prevention or treatment of deep vein thrombosis or pulmonary embolism: a review of the clinical and cost-effectiveness Low-molecular weight heparins versus warfarin for the long-term prevention or treatment of deep vein thrombosis or pulmonary embolism: a review of the clinical and cost-effectiveness Low-molecular weight heparins versus warfarin for the long-term prevention or treatment of deep vein thrombosis or pulmonary embolism (...) : a review of the clinical and cost-effectiveness CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Low-molecular weight heparins versus warfarin for the long-term prevention or treatment of deep vein thrombosis or pulmonary embolism: a review of the clinical and cost-effectiveness. Ottawa: Canadian Agency for Drugs and Technologies

2014 Health Technology Assessment (HTA) Database.

17. Portable pneumatic compression versus low-molecular-weight heparin for prevention of deep vein thrombosis after lower-extremity joint arthroplasty

Portable pneumatic compression versus low-molecular-weight heparin for prevention of deep vein thrombosis after lower-extremity joint arthroplasty Portable pneumatic compression versus low-molecular-weight heparin for prevention of deep vein thrombosis after lower-extremity joint arthroplasty Portable pneumatic compression versus low-molecular-weight heparin for prevention of deep vein thrombosis after lower-extremity joint arthroplasty Record Status This is a bibliographic record (...) of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Portable pneumatic compression versus low-molecular-weight heparin for prevention of deep vein thrombosis after lower-extremity joint arthroplasty. Lansdale: HAYES, Inc.. Healthcare Technology Brief Publication. 2014 Authors' conclusions Deep vein thrombosis (DVT) is a blood clot, or thrombus, that forms in a deep vein most commonly in the legs. DVT is serious since

2014 Health Technology Assessment (HTA) Database.

18. Portable versus non-portable intermittent pneumatic compression for prevention of postoperative deep vein thrombosis

Portable versus non-portable intermittent pneumatic compression for prevention of postoperative deep vein thrombosis Portable versus non-portable intermittent pneumatic compression for prevention of postoperative deep vein thrombosis Portable versus non-portable intermittent pneumatic compression for prevention of postoperative deep vein thrombosis Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been (...) made for the HTA database. Citation Portable versus non-portable intermittent pneumatic compression for prevention of postoperative deep vein thrombosis. Lansdale: HAYES, Inc.. Healthcare Technology Brief Publication. 2014 Authors' conclusions Deep vein thrombosis (DVT) is a blood clot, or thrombus, that forms in a deep vein most commonly in the legs. DVT is serious since the clot can dislodge and travel through the bloodstream as an embolus. If it travels through the heart and into the pulmonary

2014 Health Technology Assessment (HTA) Database.

19. Prophylaxis and Incidence of Symptomatic Deep Vein Thrombosis in Indian Patients with Sepsis: DETECT-Deep Vein Thrombosis Registry (PubMed)

Prophylaxis and Incidence of Symptomatic Deep Vein Thrombosis in Indian Patients with Sepsis: DETECT-Deep Vein Thrombosis Registry To assess thromboprophylaxis rate and incidence of symptomatic deep vein thrombosis (DVT) in Indian patients with acute sepsis.Adult patients with sepsis, within 48 h of sepsis onset/hospital admission were included. DVT was assessed using Doppler ultrasonography if clinical signs were present. Data were collected at inclusion, discharge, and 30 ± 7 days (...) /274 (67.9%) patients recovered from sepsis.Two-third patients received thromboprophylaxis. The substantial role of thromboprophylaxis in DVT prevention mandates monitoring and control of thromboprophylaxis through internal audits in hospitals.

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2017 Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

20. Asymptomatic Deep Vein Thrombosis is Associated with an Increased Risk of Death: Insights from the APEX Trial

Asymptomatic Deep Vein Thrombosis is Associated with an Increased Risk of Death: Insights from the APEX Trial  Asymptomatic deep vein thrombosis (DVT) diagnosed with compression ultrasound (CUS) is a common endpoint in trials assessing the efficacy of anticoagulants to prevent venous thromboembolism (VTE), but the relationship of asymptomatic thrombus to mortality remains uncertain. In the APEX trial (ClinicalTrials.gov: NCT01583218), 7,513 acutely ill hospitalized medical patients were

2019 EvidenceUpdates

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