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Deep Vein Thrombosis

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1. Percutaneous mechanical thrombectomy for acute deep vein thrombosis of the leg

Percutaneous mechanical thrombectomy for acute deep vein thrombosis of the leg P Percutaneous mechanical thrombectom ercutaneous mechanical thrombectomy for y for acute deep v acute deep vein thrombosis of the leg ein thrombosis of the leg Interventional procedures guidance Published: 12 June 2019 www.nice.org.uk/guidance/ipg651 Y Y our responsibility our responsibility This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising (...) mechanical thrombectomy for acute deep vein thrombosis (DVT) of the leg shows there are well-recognised but infrequent complications. © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 1 of 5For acute iliofemoral DVT the evidence on efficacy is limited in quality and quantity, therefore this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. For distal DVT

2019 National Institute for Health and Clinical Excellence - Interventional Procedures

2. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism

Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism V Venous thromboembolism in o enous thromboembolism in ov ver 16s: er 16s: reducing the risk of hospital-acquired reducing the risk of hospital-acquired deep v deep vein thrombosis or pulmonary ein thrombosis or pulmonary embolism embolism NICE guideline Published: 21 March 2018 nice.org.uk/guidance/ng89 © NICE 2019. All rights reserved. Subject to Notice of rights (https (...) in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism (NG89) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 41Contents Contents Overview 5 Who is it for? 5 Recommendations 6 1.1 Risk assessment 6 1.2 Giving information and planning for discharge 8 1.3 All patients 10 1.4 Interventions for people with acute coronary syndromes or acute stroke or for acutely ill patients 12

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

3. Deep vein thrombosis

Deep vein thrombosis Evidence Maps - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4

2018 Trip Evidence Maps

4. Point of Care Ultrasound for Assessment of Patients with Deep Vein Thrombosis in Emergency Departments: Clinical Utility and Cost-Effectiveness

Point of Care Ultrasound for Assessment of Patients with Deep Vein Thrombosis in Emergency Departments: Clinical Utility and Cost-Effectiveness Point of Care Ultrasound for Assessment of Patients with Deep Vein Thrombosis in Emergency Departments: Clinical Utility and Cost-Effectiveness | CADTH.ca Find the information you need Point of Care Ultrasound for Assessment of Patients with Deep Vein Thrombosis in Emergency Departments: Clinical Utility and Cost-Effectiveness Point of Care Ultrasound (...) for Assessment of Patients with Deep Vein Thrombosis in Emergency Departments: Clinical Utility and Cost-Effectiveness Last updated: August 29, 2019 Project Number: RB1381-000 Product Line: Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What is the clinical utility of point of care ultrasound for the assessment of patients with deep vein thrombosis in the emergency department? What is the cost effectiveness of point of care ultrasound for the assessment

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

5. Deep vein thrombosis

Deep vein thrombosis Deep vein thrombosis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Deep vein thrombosis Last reviewed: February 2019 Last updated: November 2018 Summary Patients who develop deep vein thrombosis (DVT) commonly have thromboembolic risk factors, such as cancer, trauma, major surgery, hospitalisation, immobilisation, pregnancy, or oral contraceptive use. However, many patients have no history (...) weight heparin, fondaparinux, rivaroxaban, apixaban, edoxaban, dabigatran, and/or warfarin. Generally, oral anticoagulation is continued for 3 to 6 months. In selected patients with significant thromboembolic risks, careful consideration should be given to maintaining oral anticoagulation indefinitely as long as the risks of bleeding are lower than the risks of recurrent venous thrombosis. Definition Deep vein thrombosis (DVT) is the development of a blood clot in a major deep vein in the leg, thigh

2018 BMJ Best Practice

6. Deep vein thrombosis

Deep vein thrombosis Deep vein thrombosis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Deep vein thrombosis Last reviewed: February 2019 Last updated: November 2018 Summary Patients who develop deep vein thrombosis (DVT) commonly have thromboembolic risk factors, such as cancer, trauma, major surgery, hospitalisation, immobilisation, pregnancy, or oral contraceptive use. However, many patients have no history (...) weight heparin, fondaparinux, rivaroxaban, apixaban, edoxaban, dabigatran, and/or warfarin. Generally, oral anticoagulation is continued for 3 to 6 months. In selected patients with significant thromboembolic risks, careful consideration should be given to maintaining oral anticoagulation indefinitely as long as the risks of bleeding are lower than the risks of recurrent venous thrombosis. Definition Deep vein thrombosis (DVT) is the development of a blood clot in a major deep vein in the leg, thigh

2018 BMJ Best Practice

7. Graduated compression stockings for prevention of deep vein thrombosis. Full Text available with Trip Pro

Graduated compression stockings for prevention of deep vein thrombosis. Hospitalised patients are at increased risk of developing deep vein thrombosis (DVT) in the lower limb and pelvic veins, on a background of prolonged immobilisation associated with their medical or surgical illness. Patients with DVT are at increased risk of developing a pulmonary embolism (PE). The use of graduated compression stockings (GCS) in hospitalised patients has been proposed to decrease the risk of DVT (...) . This is an update of a Cochrane Review first published in 2000, and last updated in 2014.To evaluate the effectiveness and safety of graduated compression stockings in preventing deep vein thrombosis in various groups of hospitalised patients.For this review the Cochrane Vascular Information Specialist searched the Cochrane Vascular Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL), and trials registries on 21 March 2017; and the Cochrane Vascular Specialised Register, CENTRAL

2018 Cochrane

8. Home versus in-patient treatment for deep vein thrombosis. Full Text available with Trip Pro

Home versus in-patient treatment for deep vein thrombosis. Deep vein thrombosis (DVT) occurs when a blood clot blocks blood flow through a vein, which can occur after surgery, after trauma, or when a person has been immobile for a long time. Clots can dislodge and block blood flow to the lungs (pulmonary embolism (PE)), causing death. DVT and PE are known by the term venous thromboembolism (VTE). Heparin (in the form of unfractionated heparin (UFH)) is a blood-thinning drug used during

2018 Cochrane

12. Thrombolytic therapy for pulmonary embolism and extensive iliofemoral deep vein thrombosis

Thrombolytic therapy for pulmonary embolism and extensive iliofemoral deep vein thrombosis

2017 DynaMed Plus

13. Rivaroxaban for the treatment of deep vein thrombosis and prevention of recurrent deep vein thrombosis and pulmonary embolism (TA261)

Rivaroxaban for the treatment of deep vein thrombosis and prevention of recurrent deep vein thrombosis and pulmonary embolism (TA261) Overview | Rivaroxaban for the treatment of deep vein thrombosis and prevention of recurrent deep vein thrombosis and pulmonary embolism | Guidance | NICE Rivaroxaban for the treatment of deep vein thrombosis and prevention of recurrent deep vein thrombosis and pulmonary embolism Technology appraisal guidance [TA261] Published date: 25 July 2012 Share Guidance (...) on rivaroxaban (Xarelto) for treating deep vein thrombosis and preventing a pulmonary embolism or another deep vein thrombosis in adults. Guidance development process Is this guidance up to date? . We found nothing new that affects the recommendations in this guidance. Next review : This guidance will be reviewed if there is new evidence that is likely to affect the recommendations. Your responsibility The recommendations in this guidance represent the view of NICE, arrived at after careful consideration

2012 National Institute for Health and Clinical Excellence - Technology Appraisals

14. Suspected Upper-Extremity Deep Vein Thrombosis.

Suspected Upper-Extremity Deep Vein Thrombosis. Date of origin: 1995 Last review date: 2014 ACR Appropriateness Criteria ® 1 Upper Extremity Swelling American College of Radiology ACR Appropriateness Criteria ® Clinical Condition: Upper Extremity Swelling Radiologic Procedure Rating Comments RRL* US duplex Doppler upper extremity 9 This procedure is standard for arm veins. Other modalities are required for evaluating central veins. O X-ray chest 8 This procedure is a simple evaluation of lines (...) in these procedures vary as a function of a number of factors (eg, region of the body exposed to ionizing radiation, the imaging guidance that is used). The RRLs for these examinations are designated as “Varies”. Supporting Documents For additional information on the Appropriateness Criteria methodology and other supporting documents go to www.acr.org/ac. References 1. Joffe HV, Kucher N, Tapson VF, Goldhaber SZ. Upper-extremity deep vein thrombosis: a prospective registry of 592 patients. Circulation. 2004;110

2019 American College of Radiology

15. Pentasaccharides for the treatment of deep vein thrombosis. Full Text available with Trip Pro

Pentasaccharides for the treatment of deep vein thrombosis. Standard treatment of deep vein thrombosis (DVT) is based on antithrombotic therapy, initially with parenteral administration of unfractionated heparin or low molecular weight heparins (LMWH) for five to seven days, then subsequent long-term therapy with oral vitamin K antagonists (e.g. warfarin). Pentasaccharides are novel anticoagulants that may be favourable over standard therapy due to their predictable effect, no need for frequent (...) monitoring or re-dosing, and few known drug interactions. Heparin-induced thrombocytopenia, a harmful effect of heparins, appears to be rare during treatment with pentasaccharides.To assess the efficacy and harms of pentasaccharides for the treatment of deep vein thrombosis.The Cochrane Vascular Information Specialist (CIS) searched the Specialised Register (22 March 2017) and the Cochrane Central Register of Controlled Trials (CENTRAL) (2017, Issue 2) (searched 22 March 2017). We searched clinical

2017 Cochrane

16. Thrombolysis for acute upper extremity deep vein thrombosis. Full Text available with Trip Pro

Thrombolysis for acute upper extremity deep vein thrombosis. About 5% to 10% of all deep vein thromboses occur in the upper extremities. Serious complications of upper extremity deep vein thrombosis, such as post-thrombotic syndrome and pulmonary embolism, may in theory be avoided using thrombolysis. No systematic review has assessed the effects of thrombolysis for the treatment of individuals with acute upper extremity deep vein thrombosis.To assess the beneficial and harmful effects (...) severe bleeding, pulmonary embolism, and all-cause mortality.We found no trials eligible for inclusion. We also identified no ongoing trials.There is currently insufficient evidence from which to draw conclusion on the benefits or harms of thrombolysis for the treatment of individuals with acute upper extremity deep vein thrombosis as an add-on therapy to anticoagulation, alone compared with anticoagulation, or alone compared with any other type of medical intervention. Large randomised clinical

2017 Cochrane

17. Lixiana (edoxaban) - for the prevention of embolism in patients with nonvalvular atrial fibrillation OR treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) and prevention of recurrent DVT and PE.

Lixiana (edoxaban) - for the prevention of embolism in patients with nonvalvular atrial fibrillation OR treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) and prevention of recurrent DVT and PE. Lixiana (edoxaban) × Insert searchphrase to search the website Insert searchphrase to search the website > > > Lixiana (edoxaban) Conclusion Lixiana (edoxaban) is the fourth Non-vitamin K Oral Anticoagulant (NOAC) in Denmark after Eliques (apixaban), Xarelto (rivaroxaban) and Pradaxa (...) (dabigatran). Lixiana is indicated for the prevention of embolism in patients with nonvalvular atrial fibrillation (NVAF) with one or more risk factors and treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) and prevention of recurrent DVT and PE. For either indication, Lixiana is not inferior to warfarin when it comes to preventing embolism and has a statistically significantly lower occurrence of major bleeding. The lower risk of bleeding is particularly evident in comparisons

2017 Danish Pharmacotherapy Reviews

18. Blood and Clots Series: How can I tell whether this patient has a deep vein thrombosis?

Blood and Clots Series: How can I tell whether this patient has a deep vein thrombosis? Blood and Clots Series: How can I tell whether this patient has a deep vein thrombosis? - CanadiEM Blood and Clots Series: How can I tell whether this patient has a deep vein thrombosis? In , by Kerstin de Wit February 13, 2018 All the content from the Blood & Clots series can be found . CanMEDS Roles addressed: Communicator, Collaborator, Scholar, Professional, Medical expert Case Description A patient (...) with increasing pain and edema in his left leg. In a recent hospital admission he was diagnosed with myeloma. This case reviews pretest probability of deep vein thrombosis, D-dimer and interpretation of compression ultrasound. Main Text Last week when I came onto a day shift I was handed over a patient who was waiting for an ultrasound scan. He was a 65 year old man who presented at midnight to the emergency department, 6 days after being discharged from hospital. He was diagnosed with multiple myeloma during

2018 CandiEM

19. Suspected Lower Extremity Deep Vein Thrombosis

Suspected Lower Extremity Deep Vein Thrombosis Revised 2018 ACR Appropriateness Criteria ® 1 Suspected Lower Extremity DVT American College of Radiology ACR Appropriateness Criteria ® Suspected Lower Extremity Deep Vein Thrombosis Variant 1: Suspected lower extremity deep vein thrombosis. Initial imaging. Procedure Appropriateness Category Relative Radiation Level US duplex Doppler lower extremity Usually Appropriate O CT venography lower extremity and pelvis with IV contrast May Be Appropriate (...) ??? MR venography lower extremity and pelvis without and with IV contrast May Be Appropriate O MR venography lower extremity and pelvis without IV contrast May Be Appropriate O Catheter venography pelvis and lower extremity Usually Not Appropriate ??? ACR Appropriateness Criteria ® 2 Suspected Lower Extremity DVT SUSPECTED LOWER EXTREMITY DEEP VEIN THROMBOSIS Expert Panel on Vascular Imaging: Michael Hanley, MD a ; Michael L. Steigner, MD b ; Osmanuddin Ahmed, MD c ; Ezana M. Azene, MD, PhD d

2018 American College of Radiology

20. Thrombolysis may reduce complications of deep vein thrombosis

Thrombolysis may reduce complications of deep vein thrombosis Thrombolysis may reduce complications of deep vein thrombosis Discover Portal Discover Portal Thrombolysis may reduce complications of deep vein thrombosis Published on 18 April 2017 doi: Blood clots are cleared quickly for people who develop them in the deep leg veins if they receive thrombolysis drugs alongside other treatments directly into their veins. The chance of successful break down of the clot was compared with the chance (...) of administration used made no difference to the rate of this adverse effect. This highlights the need for treatment to be targeted at people who are likely to gain most benefit, such as those with clots in the pelvis and thigh which carry higher risk of complications. Share your views on the research. Why was this study needed? Around one person in every 1,000 in the UK develops deep vein thrombosis (DVT) each year. It is usually treated with anticoagulant drugs to stop blood clots forming and reduce risk

2019 NIHR Dissemination Centre

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