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Deep Vein Thrombosis

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1. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism

Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism V Venous thromboembolism in o enous thromboembolism in ov ver 16s: er 16s: reducing the risk of hospital-acquired reducing the risk of hospital-acquired deep v deep vein thrombosis or pulmonary ein thrombosis or pulmonary embolism embolism NICE guideline Published: 21 March 2018 nice.org.uk/guidance/ng89 © NICE 2019. All rights reserved. Subject to Notice of rights (https (...) in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism (NG89) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 41Contents Contents Overview 5 Who is it for? 5 Recommendations 6 1.1 Risk assessment 6 1.2 Giving information and planning for discharge 8 1.3 All patients 10 1.4 Interventions for people with acute coronary syndromes or acute stroke or for acutely ill patients 12

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

2. Deep vein thrombosis

Deep vein thrombosis Evidence Maps - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4

2018 Trip Evidence Maps

3. Home versus in-patient treatment for deep vein thrombosis. (PubMed)

Home versus in-patient treatment for deep vein thrombosis. Deep vein thrombosis (DVT) occurs when a blood clot blocks blood flow through a vein, which can occur after surgery, after trauma, or when a person has been immobile for a long time. Clots can dislodge and block blood flow to the lungs (pulmonary embolism (PE)), causing death. DVT and PE are known by the term venous thromboembolism (VTE). Heparin (in the form of unfractionated heparin (UFH)) is a blood-thinning drug used during

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2018 Cochrane

5. Thrombolytic therapy for pulmonary embolism and extensive iliofemoral deep vein thrombosis

Thrombolytic therapy for pulmonary embolism and extensive iliofemoral deep vein thrombosis

2017 DynaMed Plus

8. Deep vein thrombosis

Deep vein thrombosis Deep vein thrombosis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Deep vein thrombosis Last reviewed: February 2019 Last updated: November 2018 Summary Patients who develop deep vein thrombosis (DVT) commonly have thromboembolic risk factors, such as cancer, trauma, major surgery, hospitalisation, immobilisation, pregnancy, or oral contraceptive use. However, many patients have no history (...) weight heparin, fondaparinux, rivaroxaban, apixaban, edoxaban, dabigatran, and/or warfarin. Generally, oral anticoagulation is continued for 3 to 6 months. In selected patients with significant thromboembolic risks, careful consideration should be given to maintaining oral anticoagulation indefinitely as long as the risks of bleeding are lower than the risks of recurrent venous thrombosis. Definition Deep vein thrombosis (DVT) is the development of a blood clot in a major deep vein in the leg, thigh

2018 BMJ Best Practice

9. Graduated compression stockings for prevention of deep vein thrombosis. (PubMed)

Graduated compression stockings for prevention of deep vein thrombosis. Hospitalised patients are at increased risk of developing deep vein thrombosis (DVT) in the lower limb and pelvic veins, on a background of prolonged immobilisation associated with their medical or surgical illness. Patients with DVT are at increased risk of developing a pulmonary embolism (PE). The use of graduated compression stockings (GCS) in hospitalised patients has been proposed to decrease the risk of DVT (...) . This is an update of a Cochrane Review first published in 2000, and last updated in 2014.To evaluate the effectiveness and safety of graduated compression stockings in preventing deep vein thrombosis in various groups of hospitalised patients.For this review the Cochrane Vascular Information Specialist searched the Cochrane Vascular Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL), and trials registries on 21 March 2017; and the Cochrane Vascular Specialised Register, CENTRAL

2018 Cochrane

10. Deep vein thrombosis

Deep vein thrombosis Deep vein thrombosis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Deep vein thrombosis Last reviewed: February 2019 Last updated: November 2018 Summary Patients who develop deep vein thrombosis (DVT) commonly have thromboembolic risk factors, such as cancer, trauma, major surgery, hospitalisation, immobilisation, pregnancy, or oral contraceptive use. However, many patients have no history (...) weight heparin, fondaparinux, rivaroxaban, apixaban, edoxaban, dabigatran, and/or warfarin. Generally, oral anticoagulation is continued for 3 to 6 months. In selected patients with significant thromboembolic risks, careful consideration should be given to maintaining oral anticoagulation indefinitely as long as the risks of bleeding are lower than the risks of recurrent venous thrombosis. Definition Deep vein thrombosis (DVT) is the development of a blood clot in a major deep vein in the leg, thigh

2018 BMJ Best Practice

11. Pentasaccharides for the treatment of deep vein thrombosis. (PubMed)

Pentasaccharides for the treatment of deep vein thrombosis. Standard treatment of deep vein thrombosis (DVT) is based on antithrombotic therapy, initially with parenteral administration of unfractionated heparin or low molecular weight heparins (LMWH) for five to seven days, then subsequent long-term therapy with oral vitamin K antagonists (e.g. warfarin). Pentasaccharides are novel anticoagulants that may be favourable over standard therapy due to their predictable effect, no need for frequent (...) monitoring or re-dosing, and few known drug interactions. Heparin-induced thrombocytopenia, a harmful effect of heparins, appears to be rare during treatment with pentasaccharides.To assess the efficacy and harms of pentasaccharides for the treatment of deep vein thrombosis.The Cochrane Vascular Information Specialist (CIS) searched the Specialised Register (22 March 2017) and the Cochrane Central Register of Controlled Trials (CENTRAL) (2017, Issue 2) (searched 22 March 2017). We searched clinical

2017 Cochrane

12. Thrombolysis for acute upper extremity deep vein thrombosis. (PubMed)

Thrombolysis for acute upper extremity deep vein thrombosis. About 5% to 10% of all deep vein thromboses occur in the upper extremities. Serious complications of upper extremity deep vein thrombosis, such as post-thrombotic syndrome and pulmonary embolism, may in theory be avoided using thrombolysis. No systematic review has assessed the effects of thrombolysis for the treatment of individuals with acute upper extremity deep vein thrombosis.To assess the beneficial and harmful effects (...) severe bleeding, pulmonary embolism, and all-cause mortality.We found no trials eligible for inclusion. We also identified no ongoing trials.There is currently insufficient evidence from which to draw conclusion on the benefits or harms of thrombolysis for the treatment of individuals with acute upper extremity deep vein thrombosis as an add-on therapy to anticoagulation, alone compared with anticoagulation, or alone compared with any other type of medical intervention. Large randomised clinical

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2017 Cochrane

13. Blood and Clots Series: How can I tell whether this patient has a deep vein thrombosis?

Blood and Clots Series: How can I tell whether this patient has a deep vein thrombosis? Blood and Clots Series: How can I tell whether this patient has a deep vein thrombosis? - CanadiEM Blood and Clots Series: How can I tell whether this patient has a deep vein thrombosis? In , by Kerstin de Wit February 13, 2018 All the content from the Blood & Clots series can be found . CanMEDS Roles addressed: Communicator, Collaborator, Scholar, Professional, Medical expert Case Description A patient (...) with increasing pain and edema in his left leg. In a recent hospital admission he was diagnosed with myeloma. This case reviews pretest probability of deep vein thrombosis, D-dimer and interpretation of compression ultrasound. Main Text Last week when I came onto a day shift I was handed over a patient who was waiting for an ultrasound scan. He was a 65 year old man who presented at midnight to the emergency department, 6 days after being discharged from hospital. He was diagnosed with multiple myeloma during

2018 CandiEM

14. Suspected Lower Extremity Deep Vein Thrombosis

Suspected Lower Extremity Deep Vein Thrombosis Revised 2018 ACR Appropriateness Criteria ® 1 Suspected Lower Extremity DVT American College of Radiology ACR Appropriateness Criteria ® Suspected Lower Extremity Deep Vein Thrombosis Variant 1: Suspected lower extremity deep vein thrombosis. Initial imaging. Procedure Appropriateness Category Relative Radiation Level US duplex Doppler lower extremity Usually Appropriate O CT venography lower extremity and pelvis with IV contrast May Be Appropriate (...) ??? MR venography lower extremity and pelvis without and with IV contrast May Be Appropriate O MR venography lower extremity and pelvis without IV contrast May Be Appropriate O Catheter venography pelvis and lower extremity Usually Not Appropriate ??? ACR Appropriateness Criteria ® 2 Suspected Lower Extremity DVT SUSPECTED LOWER EXTREMITY DEEP VEIN THROMBOSIS Expert Panel on Vascular Imaging: Michael Hanley, MD a ; Michael L. Steigner, MD b ; Osmanuddin Ahmed, MD c ; Ezana M. Azene, MD, PhD d

2018 American College of Radiology

15. Pharmacomechanical thrombectomy for iliofemoral deep vein thrombosis. (PubMed)

Pharmacomechanical thrombectomy for iliofemoral deep vein thrombosis. Deep venous thrombosis (DVT) occurs in approximately one in 1000 adults every year, and has an annual mortality of 14.6%. In particular, iliofemoral DVT can lead to recurrent thrombosis and post-thrombotic syndrome (PTS), a painful condition which can lead to chronic venous insufficiency, oedema, and ulceration. It causes significant disability, impaired quality of life, and economic burden. Early thrombus removal techniques (...) patients with an iliofemoral deep vein thrombosis were allocated to receive pharmacomechanical thrombectomy versus anticoagulation, mechanical thrombectomy, thrombolysis (systemic or catheter directed thrombolysis), or other endovascular techniques for the treatment of iliofemoral DVT.At least two review authors independently assessed studies identified for potential inclusion.We found no randomised controlled trials that met the eligibility criteria for this review. We identified one ongoing

2016 Cochrane

16. Thrombolysis for acute deep vein thrombosis. (PubMed)

Thrombolysis for acute deep vein thrombosis. Standard treatment for deep vein thrombosis aims to reduce immediate complications. Use of thrombolysis or clot dissolving drugs could reduce the long-term complications of post-thrombotic syndrome (PTS) including pain, swelling, skin discolouration, or venous ulceration in the affected leg. This is the third update of a review first published in 2004.To assess the effects of thrombolytic therapy and anticoagulation compared to anticoagulation alone (...) for the management of people with acute deep vein thrombosis (DVT) of the lower limb as determined by the effects on pulmonary embolism, recurrent venous thromboembolism, major bleeding, post-thrombotic complications, venous patency and venous function.For this update the Cochrane Vascular Information Specialist (CIS) searched the Specialised Register (February 2016). In addition the CIS searched the Cochrane Register of Studies (CENTRAL (2016, Issue 1)). Trial registries were searched for details of ongoing

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2016 Cochrane

17. Compression stockings for preventing deep vein thrombosis in airline passengers. (PubMed)

Compression stockings for preventing deep vein thrombosis in airline passengers. Air travel might increase the risk of deep vein thrombosis (DVT). It has been suggested that wearing compression stockings might reduce this risk. This is an update of the review first published in 2006.To assess the effects of wearing compression stockings versus not wearing them for preventing DVT in people travelling on flights lasting at least four hours.For this update the Cochrane Vascular Information (...) -quality evidence). There were no symptomless DVTs in three trials. Sixteen of 1804 people developed superficial vein thrombosis, four wore stockings, 12 did not (OR 0.45, 95% CI 0.18 to 1.13, P = 0.09; moderate-quality evidence). No deaths, pulmonary emboli or symptomatic DVTs were reported. Wearing stockings had a significant impact in reducing oedema (mean difference (MD) -4.72, 95% CI -4.91 to -4.52; based on six trials; low-quality evidence). A further two trials showed reduced oedema

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2016 Cochrane

18. Thrombolysis may reduce complications of deep vein thrombosis

Thrombolysis may reduce complications of deep vein thrombosis Thrombolysis may reduce complications of deep vein thrombosis Discover Portal Discover Portal Thrombolysis may reduce complications of deep vein thrombosis Published on 18 April 2017 doi: Blood clots are cleared quickly for people who develop them in the deep leg veins if they receive thrombolysis drugs alongside other treatments directly into their veins. The chance of successful break down of the clot was compared with the chance (...) of administration used made no difference to the rate of this adverse effect. This highlights the need for treatment to be targeted at people who are likely to gain most benefit, such as those with clots in the pelvis and thigh which carry higher risk of complications. Share your views on the research. Why was this study needed? Around one person in every 1,000 in the UK develops deep vein thrombosis (DVT) each year. It is usually treated with anticoagulant drugs to stop blood clots forming and reduce risk

2019 NIHR Dissemination Centre

19. Deep Vein Thrombosis: Diagnosis

Deep Vein Thrombosis: Diagnosis © 2016 Thrombosis Canada Page 1 of 6 DEEP VEIN THROMBOSIS (DVT): DIAGNOSIS OBJECTIVE: To provide an evidenced-based approach to the evaluation of patients with a clinical suspicion of deep vein thrombosis (DVT). BACKGROUND: An estimated 45,000 patients in Canada are affected by DVT each year, with an incidence of approximately 1-2 cases per 1,000 persons annually. This translates into 2-4 DVTs per year in a typical, solo Canadian family practice. Since only 10-20 (...) of DVT presence [see Deep Vein Thrombosis (DVT): Treatment guide]. The accurate exclusion of DVT also eliminates unnecessary exposure to anticoagulants, associated with inconvenience and risk of bleeding. DIAGNOSIS: The diagnosis of DVT is based on: 1) Pre-test probability (clinical suspicion) There are several formal risk models available to assess the pre-test probability of DVT. The Wells Score is the most widely used (see Table 1). Physicians can also use their clinical gestalt to determine pre

2016 Thrombosis Interest Group of Canada

20. Percutaneous mechanical thrombectomy for deep vein thrombosis

Percutaneous mechanical thrombectomy for deep vein thrombosis Percutaneous mechanical thrombectomy for deep vein thrombosis Percutaneous mechanical thrombectomy for deep vein thrombosis HAYES, Inc. Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc.. Percutaneous mechanical thrombectomy for deep vein thrombosis. Lansdale: HAYES, Inc.. Directory (...) Publication. 2016 Authors' conclusions Percutaneous mechanical thrombectomy (PMT) involves the mechanical removal of a thrombus or embolism from the vascular system using percutaneous access. PMT devices utilize various mechanisms to disrupt and remove thromboembolisms, including rheolytic, rotational, and ultrasound-assisted systems. PMT is often used in concert with local application of thrombolytic drugs. The objectives of using PMT to treat a patient with deep vein thrombosis (DVT) are to remove

2016 Health Technology Assessment (HTA) Database.

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