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Decontamination in Children

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1. Selective decontamination of the digestive tract in critically ill children: Systematic review and meta-analysis

Selective decontamination of the digestive tract in critically ill children: Systematic review and meta-analysis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2016 PedsCCM Evidence-Based Journal Club

2. Decontamination in Children

Decontamination in Children Decontamination in Children Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Decontamination in Children (...) Decontamination in Children Aka: Decontamination in Children , Pediatric Decontamination , Contaminated Casualty Management in Children From Related Chapters II. Indications Exposure Toxin Exposure III. Precautions Patients with critical injuries are decontaminated first Avoid separating families from their children unless otherwise dictated by critical medical priorities All children should have a unique identification number on wristband or similar Following , patients should be triaged for further medical

2018 FP Notebook

3. International Variability in Gastrointestinal Decontamination With Acute Poisonings. (PubMed)

International Variability in Gastrointestinal Decontamination With Acute Poisonings. Identifying international differences in the management of acute pediatric poisonings may help improve the quality of care. The objective of this study was to assess the international variation and appropriateness of gastrointestinal decontamination (GID) procedures performed in children and adolescents who present with acute poisonings to emergency departments.This was an international, multicenter, cross (...) -sectional prospective study including children <18 years with poisoning exposures presenting to 105 emergency departments in 20 countries from 8 global regions belonging to the Pediatric Emergency Research Networks. Data collection started between January and September 2013 and continued for 1 year. The appropriateness of GID procedures performed was analyzed using the American Academy of Clinical Toxicology and the European Association of Poisons Centres and Clinical Toxicologists' recommendations

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2017 Pediatrics

4. Decontamination of the pediatric patient. (PubMed)

. Additionally, children are particularly vulnerable to terrorist threats as they have unique anatomical, physiological, psychological, and developmental characteristics distinct from the adult population.Because pediatric patients are at greater risk than the general population, providers should be prepared to deliver age-appropriate care. Additionally, the ideal decontamination protocol is designed to maintain family units to maximize efficiency and minimize psychological trauma. (...) Decontamination of the pediatric patient. This article will review current guidelines for decontamination procedures for chemical, biological, and radiologic exposures with a focus on pediatric specific considerations.There has been a global increase in terrorist incidents that expose large populations to toxic agents associated with significant morbidity and mortality. The pathophysiology, treatment, and management of these toxic exposures may be unfamiliar to the healthcare provider

2016 Current Opinion in Pediatrics

5. Selective decontamination of the digestive tract in critically ill children: systematic review and meta-analysis. (PubMed)

Selective decontamination of the digestive tract in critically ill children: systematic review and meta-analysis. We examined the impact of selective decontamination of the digestive tract on morbidity and mortality in critically ill children.We searched MEDLINE, EMBASE, the Cochrane Register of Controlled Trials, and previous meta-analyses.We included all randomized controlled trials comparing administration of enteral antimicrobials in selective decontamination of the digestive tract (...) randomized controlled trials, selective decontamination of the digestive tract significantly reduced the number of children who developed pneumonia.

2013 Pediatric Critical Care Medicine

6. Decontamination in Children

Decontamination in Children Decontamination in Children Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Decontamination in Children (...) Decontamination in Children Aka: Decontamination in Children , Pediatric Decontamination , Contaminated Casualty Management in Children From Related Chapters II. Indications Exposure Toxin Exposure III. Precautions Patients with critical injuries are decontaminated first Avoid separating families from their children unless otherwise dictated by critical medical priorities All children should have a unique identification number on wristband or similar Following , patients should be triaged for further medical

2015 FP Notebook

7. Oral mucosal decontamination with chlorhexidine for the prevention of ventilator-associated pneumonia in children - a randomized, controlled trial. (PubMed)

Oral mucosal decontamination with chlorhexidine for the prevention of ventilator-associated pneumonia in children - a randomized, controlled trial. To study the efficacy of oral mucosal decontamination with chlorhexidine gel for the prevention of ventilator-associated pneumonia in children between 3 months and 15 yrs.Double blind randomized placebo controlled trial.Pediatric intensive care unit of a tertiary care hospital in North India.Eligible participants were patients aged 3 months to 15 (...) yrs who required orotracheal or nasotracheal intubation and mechanical ventilation. Two hundred eighty-three children admitted to the pediatric intensive care unit between November 2007 and April 2009 were screened. Eighty-six patients fulfilled the study requirements.Either 1% chlorhexidine or placebo gel was applied on the buccal mucosa at 8-hr intervals for the entire duration of ventilation, subject to a maximum of 21 days. Patients were followed up for the development of ventilator-associated

2012 Pediatric Critical Care Medicine

8. Gut Decontamination In Pediatric Allogeneic Hematopoietic

Gut Decontamination In Pediatric Allogeneic Hematopoietic Gut Decontamination In Pediatric Allogeneic Hematopoietic - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Gut Decontamination In Pediatric (...) decontamination" with oral antibiotics as a preventive measure for acute GVHD. There is no standard regimen for gut decontamination between transplant centers, and there are no definitive human studies showing that gut decontamination is beneficial for lowering the risk of acute GVHD. Recent studies in adult patients undergoing stem cell transplant indicate that the types of bacteria living in the intestine can influence bone marrow transplant outcomes such as survival and development of acute GVHD. Some

2015 Clinical Trials

9. Decolonization and decontamination: what's their role in infection control? (PubMed)

Decolonization and decontamination: what's their role in infection control? Hospital-acquired infections cause up to 19% of infections in paediatric patients contributing to the spread of antimicrobial resistance. This review evaluates the effect of decolonization and decontamination in hospitalized children and neonates as an adjunct to standard infection control measures.Few studies on decolonization and decontamination are available in children. The evidence about the effectiveness of daily (...) chlorhexidine washcloths on bacteraemia in paediatric patients relies on a single randomized controlled trial, in neonates with central venous access in a single retrospective observational study. It is uncertain whether nasal mupirocin reduces methicillin-resistant Staphylococcus aureus carriage and infections in neonates, whereas oral chlorhexidine mouthwashes have not proven effective in children in intensive care settings. Scanty evidence demonstrates a reduction in the rate of ventilation-acquired

2015 Current Opinion in Infectious Diseases

10. 70% Ethanol for Decontamination of CVL Exposed to Calcineurine Inhibitors Version 1.0, 1/9/2014

70% Ethanol for Decontamination of CVL Exposed to Calcineurine Inhibitors Version 1.0, 1/9/2014 70% Ethanol for Decontamination of CVL Exposed to Calcineurine Inhibitors Version 1.0, 1/9/2014 - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. 70% Ethanol for Decontamination of CVL Exposed to Calcineurine Inhibitors Version 1.0, 1/9/2014 (70% EtOH) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02441075 Recruitment Status : Completed First Posted : May 12, 2015 Last Update Posted : January 29, 2016

2015 Clinical Trials

11. Policies to support practice areas caring for neonates, children and young people

Policies to support practice areas caring for neonates, children and young people Policies to support clinical practice in caring for neonates, children and young peopleRCN Legal Disclaimer This publication contains information, advice and guidance to help members of the RCN. It is intended for use within the UK but readers are advised that practices may vary in each country and outside the UK. The information in this publication has been compiled from professional sources, but its accuracy (...) , resold, hired out or otherwise disposed of by ways of trade in any form of binding or cover other than that in which it is published, without the prior consent of the Publishers. Policies to support clinical practice in caring for neonates, children and young people Contents 1 Introduction 1 2 Definitions 2 3 Policy management 2 4 Policy index 3 – Human resource policies and their 3 purpose – Management/administration policies 8 – Clinical policies 11 – Medicines management policies 15 – Safeguarding

2014 Royal College of Nursing

12. Determinants of stunting among children aged 6-59 months at Kindo Didaye woreda, Wolaita Zone, Southern Ethiopia: Unmatched case control study. (PubMed)

Determinants of stunting among children aged 6-59 months at Kindo Didaye woreda, Wolaita Zone, Southern Ethiopia: Unmatched case control study. Stunting is a well-established risk marker of poor child development. Globally in 2017, 155 million children under 5 were estimated to be stunted. While different activities are being done to reduce the burden of stunted growth, the problem is overwhelming in Africa; it was increased by 24%. Therefore, identifying determinants of stunting among children (...) aged 6-59 would help to set priorities for action and to the design of stunting reduction plan at a grassroots level.The unmatched case-control study was conducted in randomly selected 8 rural kebeles of Kindo Didaye woreda, Ethiopia from February to April, 2016 to identify the determinants of stunting among children aged 6-59 months. The sampling frame was identified by enumeration of 6-59 months of age children in the entire households of the study area. From which 155 as cases and 310

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2017 PLoS ONE

13. Individual external doses below the lowest reference level of 1 mSv per year five years after the 2011 Fukushima nuclear accident among all children in Soma City, Fukushima: A retrospective observational study. (PubMed)

from external exposure after the accident and the effects of decontamination on external exposure. This study considered all children less than 16 years of age in Soma City, Fukushima who participated in annual voluntary external exposure screening programs during the five years after the accident (n = 5,363). In total, 14,405 screening results were collected. The median participant age was eight years. The geometric mean levels of annual additional doses from external exposure attributable (...) Individual external doses below the lowest reference level of 1 mSv per year five years after the 2011 Fukushima nuclear accident among all children in Soma City, Fukushima: A retrospective observational study. After the 2011 Fukushima Daiichi nuclear power plant accident, little information has been available on individual doses from external exposure among residents living in radioactively contaminated areas near the nuclear plant; in the present study we evaluated yearly changes in the doses

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2017 PLoS ONE

14. Guidelines for Insertion and Maintenance of Central Venous Access Devices in Children and Young People

Guidelines for Insertion and Maintenance of Central Venous Access Devices in Children and Young People GUIDELINES FOR INSERTION AND MAINTENANCE OF CENTRAL VENOUS ACCESS DEVICES IN CHILDREN AND YOUNG PEOPLE Issued August 2012 updated in January 20141 CONTENTS PREFACE 03 INTRODUCTION 04 AIMS OF GUIDELINE 05 CARE BUNDLE APPROACH 06 PATHOGENESIS 07 PROCEDURE FOR INSERTION OF CENTRAL VENOUS CATHETER 08 BEST PRACTICE PRINCIPLES WHEN ACCESSING THE CVAD 10 PROCEDURE FOR THE ADMINISTRATION OF DRUGS VIA (...) devices (e.g. Port-a-Cath ® ) APPENDICES Appendix 1 – Review of the evidence 23 Appendix 2 – Central Venous Catheter Insertion Checklist 25 Appendix 3 – Summary of general principle and rationale 26 Appendix 4 – Central Venous Catheter insertion & removal details 27 Appendix 5 – Central Venous Access Device Patient Record 28 Appendix 6 – Summary of types of central venous catheter 29 used in the children Appendix 7 – Audit Tool 30 REFERENCES AND FURTHER READING 32 MEMBERSHIP OF GAIN WORKING GROUP 343

2014 Regulation and Quality Improvement Authority

15. Influences of High-fiber, Organic Whole-food Formula on the Gut Microbiome in Critically Ill Children

/treatment Phase Critical Illness Dysbiosis Pediatric ALL Other: Nourish Other: Pediasure Not Applicable Detailed Description: The gastrointestinal microbiome has been shown to be altered in critically-ill children such that there is a larger shift toward pathogenic bacteria. Previous studies have shown that probiotics, fecal transplants, antibiotic decontamination, and dietary interventions can shift the gastrointestinal microbiome toward a metabolically favorable microbiome profile and be associated (...) Influences of High-fiber, Organic Whole-food Formula on the Gut Microbiome in Critically Ill Children Influences of High-fiber, Organic Whole-food Formula on the Gut Microbiome in Critically Ill Children - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2018 Clinical Trials

16. Lead Pellet Ingestion in 3 Children: Another Source for Lead Toxicity. (PubMed)

Lead Pellet Ingestion in 3 Children: Another Source for Lead Toxicity. Acute ingestions of spherical lead ammunition foreign bodies such as bullets and lead shot can cause acute blood lead level elevations and clinical symptoms necessitating emergency department evaluations and sometimes treatment. This article presents 3 cases of children ingesting lead ammunition, all receiving gastrointestinal (GI) decontamination and chelation therapy for significantly elevated blood lead level. Case

2018 Pediatric Emergency Care

17. International Guideline for the Management of Fever and Neutropenia in Children with Cancer and/or Undergoing Hematopoietic Stem Cell Transplantation

International Guideline for the Management of Fever and Neutropenia in Children with Cancer and/or Undergoing Hematopoietic Stem Cell Transplantation 1 TITLE: Guideline for the Management of Fever and Neutropenia in Children with Cancer and/or Undergoing Hematopoietic Stem Cell Transplantation (Long Version) RUNNING HEAD: Pediatric fever and neutropenia guideline AUTHORS: Thomas Lehrnbecher * 1 , Robert Phillips* 2 , Sarah Alexander 3 , Frank Alvaro 6 , Fabianne Carlesse 7 , Brian Fisher 8 (...) for Reviews and Dissemination, University of York, York, UK; 3 Division of Hematology/Oncology, 4 Program in Child Health Evaluative Sciences, and 5 Department of Pharmacy, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada; 6 John Hunter Children's Hospital, Locked Bag 1, Hunter Region Mail Centre, Newcastle, NSW 2310, Australia; 7 Pediatric Oncology Institute, GRAACC/Federal University of São Paulo (UNIFESP-EPM), São Paulo, Brazil; 8 Division of Infectious Diseases

2012 SickKids Supportive Care Guidelines

18. Sialanar (glycopyrronium) - for treating severe drooling of saliva in children and adolescents (aged 3 years and above) with conditions affecting the nervous system, such as cerebral palsy, epilepsy and neurodegenerative diseases

Sialanar (glycopyrronium) - for treating severe drooling of saliva in children and adolescents (aged 3 years and above) with conditions affecting the nervous system, such as cerebral palsy, epilepsy and neurodegenerative diseases 30 Churchill Place ? Canary Wharf ? London E14 5EU ? United Kingdom An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5520 Send a question via our website www.ema.europa.eu/contact 21 July 2016 EMA/555265/2016 Committee (...) Manufacturer ASMF Active Substance Master File (Drug Master File) ATC Anatomical Therapeutic Chemical Classification System AUC area under the time-concentration curve AUC (0-t) area under the plasma concentration vs. time curve, from time zero to t, where t was the last quantifiable concentration AUC (0-a) area under the plasma concentration vs. time curve, with extrapolation to infinity BA bioavailability BE bioequivalence BMI Body Mass Index BNFc British National Formulary for Children BP British

2016 European Medicines Agency - EPARs

19. Stool Culture for Diagnosis of Pulmonary Tuberculosis in Children (PubMed)

respiratory specimens. After decontamination/digestion with NALC (N-acetyl-l-cysteine)-NaOH (1.25%), concentrated fluorescent smear microscopy, Xpert MTB/RIF, and liquid culture were completed for all specimens. Culture contamination of stool specimens was high at 41.5%. Seven of 90 (7.8%) children initiating TB treatment were stool culture positive for M. tuberculosis Excluding contaminated cultures, the sensitivity of stool culture versus confirmed TB was 6/25 (24.0%; 95% confidence interval [CI] = 9.4 (...) Stool Culture for Diagnosis of Pulmonary Tuberculosis in Children Bacteriological confirmation of Mycobacterium tuberculosis is achieved in the minority of young children with tuberculosis (TB), since specimen collection is resource intensive and respiratory secretions are mostly paucibacillary, leading to limited sensitivity of available diagnostic tests. Although molecular tests are increasingly available globally, mycobacterial culture remains the gold standard for diagnosis

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2017 Journal of clinical microbiology

20. IDSA Clinical Practice Guideline for Acute Bacterial Rhinosinusitis in Children and Adults

IDSA Clinical Practice Guideline for Acute Bacterial Rhinosinusitis in Children and Adults We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. IDSA Clinical Practice Guideline for Acute Bacterial Rhinosinusitis in Children and Adults | Clinical Infectious Diseases | Oxford Academic Search Account Menu Menu Navbar Search Filter Mobile Microsite Search Term Close search (...) filter search input Article Navigation Close mobile search navigation Article navigation 15 April 2012 Article Contents Article Navigation IDSA Clinical Practice Guideline for Acute Bacterial Rhinosinusitis in Children and Adults Anthony W. Chow 1Division of Infectious Diseases, Department of Medicine, University of British Columbia, Vancouver, Canada Search for other works by this author on: Michael S. Benninger 2Otolaryngology, The Head and Neck Institute, Cleveland Clinic, Ohio Search for other

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2012 Infectious Diseases Society of America

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