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Decontamination in Children

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1. Selective decontamination of the digestive tract in critically ill children: Systematic review and meta-analysis

Selective decontamination of the digestive tract in critically ill children: Systematic review and meta-analysis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2016 PedsCCM Evidence-Based Journal Club

2. GENANO 5250 Medical Grade Air Decontamination Unit

) were also included. Effectiveness Mossad IM et al. (2018) reported the performance of Genano ® 4500 air decontamination unit employed in one operating room of a paediatric surgery department. Air samples were taken between April 2017 and April 2018. Prior to installation of the equipment, the operation room studied was classified as ISO Class 8, following the ISO 14644 standardization. Particle sizes of 0.3 µm, 0.5 µm, 1.0 µm, 2.5 µm, 5.0 µm and 10.0 µm were measured using a portable dust monitor (...) GENANO 5250 Medical Grade Air Decontamination Unit To provide scientific evidence on the effectiveness and safety of Genano ® 5250 air decontamination unit in improving indoor air quality, especially in hospital settings. This brief was conducted based on a request from the Disease Control Division, Ministry of Health (MOH) Malaysia following an email from a local distributor advocating the use of this device in MOH facilities. Ventilation plays a crucial role in maintaining a clean indoor

2020 MaHTAS Covid-19 Rapid Evidence Updates

3. Decontamination in Children

Decontamination in Children Decontamination in Children Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Decontamination in Children (...) Decontamination in Children Aka: Decontamination in Children , Pediatric Decontamination , Contaminated Casualty Management in Children From Related Chapters II. Indications Exposure Toxin Exposure III. Precautions Patients with critical injuries are decontaminated first Avoid separating families from their children unless otherwise dictated by critical medical priorities All children should have a unique identification number on wristband or similar Following , patients should be triaged for further medical

2018 FP Notebook

4. PICS Guidance on management of critically ill children with Covid-19 infection

in children. Weiss SL, Peters MJ, Alhazzani W, et al. Intensive Care Med. 2020 Feb;46(Suppl 1):10-67. doi: 10.1007/s00134-019-05878-6. How to manage a paediatric cardiac arrest in suspected/confirmed cases • Do not use the hospital cardiac arrest team • Devise a modified protocol beforehand with identified members of senior paediatric team and ensure all are mask fit tested and able to don and doff PPE • If the child is intubated and ventilated – try not to disconnect from the ventilator when doing CPR (...) PICS Guidance on management of critically ill children with Covid-19 infection Sinha/Ramnarayan/Fraser v4.0 14.03.20 PAEDIATRIC CRITICAL CARE COVID-19 GUIDANCE Key points • Coronavirus (COVID-19) is an air-borne disease, characterized by its ability to spread rapidly among healthcare staff who are not properly protected. It can be difficult to rapidly diagnose and has a high case-fatality rate in adults but generally appears to be a mild illness in children. • The key considerations for all

2020 Covid-19 Ad hoc guidelines

5. Consensus guidelines for managing the airway in children with COVID-19

Consensus guidelines for managing the airway in children with COVID-19 1 Consensus guidelines for managing the airway in children with COVID-19; Highlighting differences in practice from adult guidelines Guidelines from the Association of Anaesthetists, the Difficult Airway Society, the Intensive Care Society, the Faculty of Intensive Care Medicine and the Royal College of Anaesthetists, Paediatric Intensive Care Society, Association of Paediatric Anaesthetists T. M. Cook, 1 K. El-Boghdadly, 2 (...) Lothian, Edinburgh, UK 5 Consultant, Department of Anaesthesia, Royal National Throat Nose and Ear Hospital and University College London Hospitals NHS Foundation Trust, London, UK 6 Consultant, Department of Anaesthesia and Intensive Care Medicine, Warrington and Halton NHS Foundation Trust, Warrington, UK 7 Consultant, Paediatric Intensive Care, Bristol Royal Hospital for Children, UK 8 Children’s Acute Transport Service (CATS), Great Ormond Street Hospital, UK 9 Consultant, Paediatric Intensive

2020 ICM Anaesthesia COVID-19

6. Paediatric tracheostomy and tracheostomy long-term ventilated care during the COVID-19 pandemic

admission to hospital or HDU/ICU to maximise available resources Page 3 of 16 Paediatric Tracheostomy and Tracheostomy Long-Term Ventilated Care during the COVID Pandemic 07/04/2020 C. Doherty, R.Neal, S.Wilkinson, N.Bateman, I,Bruce, J.Russell, B.A.McGrath on behalf of the Paediatric working party NTSP www.tracheostomy.org.uk 2. Delivery of Established Care It is proposed that, for children who require Tracheostomy or Tracheostomy Long-Term Ventilation (Tracheostomy-LTV) care, the best approach (...) cleaning/changing of outer gloves/gown or apron between patients). High Risk Areas include: • Areas where COVID positive patients are managed • Areas where patients with an unknown but suspected COVID status are managed • Areas where Aerosol Generating Procedures occur frequently (ventilated children, including children with tracheostomies and tracheostomy-LTV) Page 5 of 16 Paediatric Tracheostomy and Tracheostomy Long-Term Ventilated Care during the COVID Pandemic 07/04/2020 C. Doherty, R.Neal

2020 ICM Anaesthesia COVID-19

7. Decontamination of the pediatric patient. (Abstract)

. Additionally, children are particularly vulnerable to terrorist threats as they have unique anatomical, physiological, psychological, and developmental characteristics distinct from the adult population.Because pediatric patients are at greater risk than the general population, providers should be prepared to deliver age-appropriate care. Additionally, the ideal decontamination protocol is designed to maintain family units to maximize efficiency and minimize psychological trauma. (...) Decontamination of the pediatric patient. This article will review current guidelines for decontamination procedures for chemical, biological, and radiologic exposures with a focus on pediatric specific considerations.There has been a global increase in terrorist incidents that expose large populations to toxic agents associated with significant morbidity and mortality. The pathophysiology, treatment, and management of these toxic exposures may be unfamiliar to the healthcare provider

2016 Current Opinion in Pediatrics

8. Clostridioides difficile Infection in Adults and Children

are present (see Table 3B). • For pediatric patients meeting severe or fulminant clinical criteria (Table 3B), or having risk factors associated with severe CDI disease (Table 3B), testing should be performed as described above (Figure 2), and empiric therapy should be strongly considered while awaiting results. The majority of CDI in infants and children is of mild to moderate disease severity criteria. 21,22,63 Applying the same criteria for adult severe disease to pediatric populations tends (...) in Adults and Children 12/2019 Key Points for Patients =18 Years of Age: Diagnosis The decision to test children for CDI is complicated given a high rate of asymptomatic carriage, especially in infants 15,000 cells/mm 3 ]) ? Abdominal pain with radiographic evidence of bowel thickening ? Radiographic evidence of toxic megacolon OR 2. Colonoscopic or histopathologic evidence of pseudomembranous colitis. 6 UMHS C. difficile Infection in Adults and Children 12/2019 Table 3A. Classification and Treatment

2020 University of Michigan Health System

9. Gut Decontamination In Pediatric Allogeneic Hematopoietic

Gut Decontamination In Pediatric Allogeneic Hematopoietic Gut Decontamination In Pediatric Allogeneic Hematopoietic - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Gut Decontamination In Pediatric (...) : A Randomized Phase 2 Study to Examine the Impact of Gut Decontamination on Intestinal Microbiome Composition in Pediatric Allogeneic Hematopoietic Stem Cell Transplant Patients Study Start Date : March 2016 Estimated Primary Completion Date : October 2019 Estimated Study Completion Date : May 2023 Resource links provided by the National Library of Medicine available for: resources: Arms and Interventions Go to Arm Intervention/treatment Active Comparator: Gut Decontamination with vancopoly All eligible

2015 Clinical Trials

10. Multidisciplinary guidelines for the management of paediatric tracheostomy emergencies Full Text available with Trip Pro

via the stoma. Figure 6 Paediatric facemask (left) and supraglottic airway device (right) applied to an infant's stoma can provide effective oxygenation and ventilation. If non‐invasive primary measures fail to oxygenate the child, more invasive secondary techniques may be required. Intubation may be achieved via the upper airway using standard techniques, recognising that the incidence of difficult airways in children with tracheostomies is high . Difficult SAD ventilation and facemask (...) guidelines for the management of paediatric tracheostomy emergencies Corresponding Author Consultant E-mail address: Department of Paediatric Anaesthesia, Manchester University NHS Foundation Trust, Manchester, UK Correspondence to: C. Doherty Email: Consultant Paediatric Intensive Care Medicine, Paediatrics, Birmingham Children's Hospital, Birmingham, UK Tracheostomy Specialist Nurse Department of Paediatric ENT, Manchester University NHS Foundation Trust, Manchester, UK Tracheostomy Specialist Nurse

2018 Association of Paediatric Anaesthetists of Great Britain and Ireland

11. International Variability in Gastrointestinal Decontamination With Acute Poisonings. Full Text available with Trip Pro

International Variability in Gastrointestinal Decontamination With Acute Poisonings. Identifying international differences in the management of acute pediatric poisonings may help improve the quality of care. The objective of this study was to assess the international variation and appropriateness of gastrointestinal decontamination (GID) procedures performed in children and adolescents who present with acute poisonings to emergency departments.This was an international, multicenter, cross (...) -sectional prospective study including children <18 years with poisoning exposures presenting to 105 emergency departments in 20 countries from 8 global regions belonging to the Pediatric Emergency Research Networks. Data collection started between January and September 2013 and continued for 1 year. The appropriateness of GID procedures performed was analyzed using the American Academy of Clinical Toxicology and the European Association of Poisons Centres and Clinical Toxicologists' recommendations

2017 Pediatrics

12. Efficacy of Er:YAG Laser in Decontamination of Dental Implants: An In-Vitro Study

Efficacy of Er:YAG Laser in Decontamination of Dental Implants: An In-Vitro Study Efficacy of Er:YAG Laser in Decontamination of Dental Implants: An In-Vitro Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding (...) more. Efficacy of Er:YAG Laser in Decontamination of Dental Implants: An In-Vitro Study The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03100435 Recruitment Status : Recruiting First Posted : April 4, 2017 Last Update

2017 Clinical Trials

13. Human Milk Storage Information for Home Use for Full-Term Infants

D , Ahrabi AF , Codipilly CN, et al. Do thawing and warming affect the integrity of human milk? J Perinatol 2014 ;34:863–866. , , 45 Lönnerdal B . Bioactive proteins in breast milk . J Paediatr Child Health 2013 ;49 Suppl 1:1–7. , , 46 Akinbi H , Meinzen-Derr J , Auer C, et al. Alterations in the host defense properties of human milk following prolonged storage or pasteurization . J Pediatr Gastroenterol Nutr 2010 ;51:347–352. , 47 Thatrimontrichai A , Janjindamai W , Puwanant M . Fat loss (...) of human milk should be labeled with the date of milk expression and the name of the child if the milk will be used in a child-care setting. It is typical for infants in daycare to take 60–120 mL (2–4 ounces) of human milk at one feeding. Therefore, storing human milk in a variety of small increments such as 15–60 mL is a convenient way to prevent waste of thawed human milk. 7. Mixing milk: Freshly expressed warm milk should not be added to already cooled or frozen milk, to prevent rewarming

2017 Academy of Breastfeeding Medicine

14. Decontamination

Decontamination Decontamination Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Decontamination Decontamination Aka: Decontamination (...) , M291 , Hypochlorite From Related Chapters II. Indications Exposure Toxin Exposure III. Protocol: Step 1 - Removal of contaminated clothing and triage See IV. Protocol: Step 2 - Physical Removal of contaminant within 1-2 minutes Preferred method for Decontamination: Shower Immediate rinsing with copious water and soap Alternatives if water not available or limited Dry powder: detergent, earth, flour Wipe with wet tissue paper V. Protocol: Step 3 - Decontamination Agents M291 Resin Kit for spot

2018 FP Notebook

15. Decontamination After Toxin Exposure

Decontamination After Toxin Exposure Decontamination After Toxin Exposure Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Decontamination After Toxin Exposure Decontamination After Toxin Exposure Aka: Decontamination After Toxin Exposure , Decontamination After Toxin Ingestion , Gastric Decontamination II. Protocol: Gastric Decontamination Indications Severe ingestion cases as directed by poison control Gastric Decontamination is no longer recommended for most ingestions Techniques s III. Protocol: Skin Decontamination (e.g. chemical exposure) Remove all clothing and wash skin with soap and water Protect health care workers from

2018 FP Notebook

16. Sialanar (glycopyrronium) - for treating severe drooling of saliva in children and adolescents (aged 3 years and above) with conditions affecting the nervous system, such as cerebral palsy, epilepsy and neurodegenerative diseases

) No 1901/2006. The eligibility to the centralised procedure was agreed upon by the EMA/CHMP on 24 October 2013. The applicant applied for the following indication: Treatment of sialorrhoea (chronic pathological drooling) in children aged 2 to M3 > M2/M4 > M5. GP is 2-4 times more selective for the M3 and M1 subtypes than M2, making it one of the most potent M3 blockers available (Bird et al. 2011). The applied dose is based on the weight of the child, starting with approximately 0.02 mg/kg per dose (...) to the chronic dosing regimen of glycopyrronium bromide in children proposed for this application. Extrapolation of safety margins to the paediatric population is not possible, as no exposure data are available from repeated dose toxicology studies and no studies in juvenile animals have been performed with glycopyrronium bromide. In the absence of robust bibliographic data to the chronic oral dosing in the paediatric population is not supported. The Applicant refers to non-clinical genotoxicity

2016 European Medicines Agency - EPARs

17. Quality Standards for Paediatric Gastroenterology, Hepatology & Nutrition

, for example uncomplicated constipation and functional abdominal pain. The standards will reduce variation in care; ensuring equitable services are available for all infants, children and young people. Ultimately, they will promote the best health outcomes and quality of life for children and their families. The Royal College of Paediatrics and Child Health together with the British Society of Paediatric Gastroenterology, Hepatology and Nutrition play key roles in promoting standards of clinical practice (...) of acute paediatric service standards in the UK. 2013. Available from http://www.rcpch.ac.uk/sites/default/files/page/Back%20to%20Facing%20the%20Future%2 0FINAL.pdf 4. Royal College of Paediatrics and Child Health. & Us® RCPCH Children and Young People’s Roadshow. Key Themes from the Long Term Conditions Consultation. 2016. 5. Yassaee A., Hale D., Armitage A., et al. Optimising healthcare transitions for young people: A systematic review of reviews. Archives of Disease in Childhood 2016; 101(Suppl 1

2017 British Society of Paediatric Gastroenterology Hepatology and Nutrition

18. Guidelines for caring for an infant, child, or young person who requires enteral feeding

Guidelines for caring for an infant, child, or young person who requires enteral feeding 1 Guidelines for caring for an infant, child, or young person who requires enteral feeding FEBRUARY 2015 2 Contents Preface 3 Aims of Guidelines 4 Enteral Feeding 5 Enteral Feeding Devices 6 Enteral Device Essentials 8 Discharging a child from hospital to home following insertion of an enteral feeding device 9 Competency Based Training 9 Infection Prevention and Control in Enteral Feeding 10 Post-Insertion (...) Project Lead Lead Nurse Community Children’s Nursing Western Health and Social Care Trust. 4 Aims of Guidelines The aims of this clinical guideline are to: ? Ensure that all practices associated with the commencement, care, management and replacement of enteral feeding devices in infants, children and young people are based on the best current evidence. ? Standardise practice both for the management of enteral feeding and replacement of enteral feeding devices across all Health and Social Care Trusts

2015 Regulation and Quality Improvement Authority

19. Microbial contamination of home nebulizers in children with cystic fibrosis and clinical implication on the number of pulmonary exacerbations. Full Text available with Trip Pro

Microbial contamination of home nebulizers in children with cystic fibrosis and clinical implication on the number of pulmonary exacerbations. Early detection of pulmonary contamination in children with cystic fibrosis (CF) is essential since these children are vulnerable to Pseudomonas aeruginosa (P. aeruginosa) colonization. In Iran, home nebulization of antibiotics is a widespread practice in treatment for patients with CF and, to the best our knowledge, no bacteriological surveys have been (...) conducted till date in this regard.This observational, cross sectional study was conducted on 61 children with CF at Mofid Children's Hospital, Tehran, from September 2017 to march 2018. The swab sampling was performed from 61 home nebulizers used by children diagnosed with CF. Contemporaneous sputum sample or deep nasopharyngeal swab was taken from each patient for bacterial and fungal testing. Medical records of the patients were reviewed and the number of exacerbations were recorded over the last 12

2020 BMC pulmonary medicine

20. Decontamination in Children

Decontamination in Children Decontamination in Children Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Decontamination in Children (...) Decontamination in Children Aka: Decontamination in Children , Pediatric Decontamination , Contaminated Casualty Management in Children From Related Chapters II. Indications Exposure Toxin Exposure III. Precautions Patients with critical injuries are decontaminated first Avoid separating families from their children unless otherwise dictated by critical medical priorities All children should have a unique identification number on wristband or similar Following , patients should be triaged for further medical

2015 FP Notebook

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