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Decision Analysis

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1. Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer: a systematic review and economic analysis

Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer: a systematic review and economic analysis Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer: a systematic review and economic analysis Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website (...) , Sue Ward 1 , Ruth Wong 1 , Robert C Stein 2, 3 , Janet Brown 4 1 Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, UK 2 University College London Hospitals Biomedical Research Centre, London, UK 3 Research Department of Oncology, University College London, London, UK 4 Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK * Corresponding author Email: {{metadata.Journal}} Volume: {{metadata.Volume}}, Issue

2019 NIHR HTA programme

2. Risk scores to guide referral decisions for people with suspected ovarian cancer in secondary care: a systematic review and cost-effectiveness analysis

Risk scores to guide referral decisions for people with suspected ovarian cancer in secondary care: a systematic review and cost-effectiveness analysis Risk scores to guide referral decisions for people with suspected ovarian cancer in secondary care: a systematic review and cost-effectiveness analysis Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose

2018 NIHR HTA programme

3. Selecting pregnant or postpartum women with suspected pulmonary embolism for diagnostic imaging: the DiPEP diagnostic study with decision-analysis modelling

Selecting pregnant or postpartum women with suspected pulmonary embolism for diagnostic imaging: the DiPEP diagnostic study with decision-analysis modelling Selecting pregnant or postpartum women with suspected pulmonary embolism for diagnostic imaging: the DiPEP diagnostic study with decision-analysis modelling Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found (...) . Please choose a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} Clinical features, decision rules and biomarkers do not accurately select pregnant or postpartum women with suspected pulmonary embolism for diagnostic imaging. {{author}} {{($index , , , , , , , , , & . Steve Goodacre 1, * , Kimberley Horspool 1 , Neil Shephard 1 , Daniel Pollard 1 , Beverley J

2018 NIHR HTA programme

4. What is the added value of ultrasound joint examination for monitoring synovitis in rheumatoid arthritis and can it be used to guide treatment decisions? A systematic review and cost-effectiveness analysis

What is the added value of ultrasound joint examination for monitoring synovitis in rheumatoid arthritis and can it be used to guide treatment decisions? A systematic review and cost-effectiveness analysis What is the added value of ultrasound joint examination for monitoring synovitis in rheumatoid arthritis and can it be used to guide treatment decisions? A systematic review and cost-effectiveness analysis Journals Library An error occurred retrieving content to display, please try again

2018 NIHR HTA programme

5. Rapid methods including network meta-analysis to produce evidence in clinical decision support: a decision analysis. (Full text)

Rapid methods including network meta-analysis to produce evidence in clinical decision support: a decision analysis. Conducting systematic reviews is time-consuming but crucial to construct evidence-based patient decision aids, clinical practice guidelines and decision analyses. New methods might enable developers to produce a knowledge base more rapidly. However, trading off scientific rigour for speed when creating a knowledge base is controversial, and the consequences are insufficiently (...) known. We developed and applied faster methods including systematic reviews and network meta-analyses, assessed their feasibility and compared them to a gold standard approach. We also assessed the feasibility of using decision analysis to perform this comparison.Long-term treatment in bipolar disorder was our testing field. We developed two new methods: an empirically based, rapid network meta-analysis (NMA) and an expert NMA, and conducted a patient survey. We applied these methods to collect

2018 Systematic Reviews PubMed

6. Spot protein-creatinine ratio and spot albumin-creatinine ratio in the assessment of pre-eclampsia: a diagnostic accuracy study with decision-analytic model-based economic evaluation and acceptability analysis

Spot protein-creatinine ratio and spot albumin-creatinine ratio in the assessment of pre-eclampsia: a diagnostic accuracy study with decision-analytic model-based economic evaluation and acceptability analysis Spot protein-creatinine ratio and spot albumin-creatinine ratio in the assessment of pre-eclampsia: a diagnostic accuracy study with decision-analytic model-based economic evaluation and acceptability analysis Journals Library An error occurred retrieving content to display, please try

2017 NIHR HTA programme

7. The REFER (REFer for EchocaRdiogram) study: a prospective validation and health economic analysis of a clinical decision rule, NT-proBNP or their combination in the diagnosis of heart failure in primary care

The REFER (REFer for EchocaRdiogram) study: a prospective validation and health economic analysis of a clinical decision rule, NT-proBNP or their combination in the diagnosis of heart failure in primary care The REFER (REFer for EchocaRdiogram) study: a prospective validation and health economic analysis of a clinical decision rule, NT-proBNP or their combination in the diagnosis of heart failure in primary care Journals Library An error occurred retrieving content to display, please try again

2017 NIHR HTA programme

8. Do our risk preferences change when we make decisions for others? A meta-analysis of self-other differences in decisions involving risk. (Full text)

Do our risk preferences change when we make decisions for others? A meta-analysis of self-other differences in decisions involving risk. Are we more risk-averse or risk-seeking when we make decisions on behalf of other people as opposed to ourselves? So far, findings have not been able to provide a clear and consistent answer.We propose a meta-analysis to assess whether self-other differences vary according to particular features of the decision. We reviewed 78 effect sizes from 49 studies (...) (7,576 participants).There was no overall self-other difference, but there were moderating effects of domain and frame. Decisions in the interpersonal domain were more risk-averse for self than for other. Decisions in the medical domain were more risk-seeking for self than for other. There were no overall self-other differences in the financial domain, however there was a moderating effect of frame: decisions in a gain frame were more risk-averse for self than other whereas decisions in a loss frame

2019 PLoS ONE PubMed

9. Decision aids for people facing health treatment or screening decisions. (Full text)

were behavioural, health, and health system effects.We pooled results using mean differences (MDs) and risk ratios (RRs), applying a random-effects model. We conducted a subgroup analysis of studies that used the patient decision aid to prepare for the consultation and of those that used it in the consultation. We used GRADE to assess the strength of the evidence.We included 105 studies involving 31,043 participants. This update added 18 studies and removed 28 previously included studies comparing (...) to usual care in four studies. People receiving decision aids do not appear to differ from those receiving usual care in terms of anxiety, general health outcomes, and condition-specific health outcomes. Studies did not report adverse events associated with the use of decision aids.In subgroup analysis, we compared results for decision aids used in preparation for the consultation versus during the consultation, finding similar improvements in pooled analysis for knowledge and accurate risk perception

2017 Cochrane PubMed

10. Feasibility and Efficacy of Decision Aids to Improve Decision Making for Postmastectomy Breast Reconstruction: A Systematic Review and Meta-analysis. (PubMed)

Feasibility and Efficacy of Decision Aids to Improve Decision Making for Postmastectomy Breast Reconstruction: A Systematic Review and Meta-analysis. The decision-making process for women considering breast reconstruction following mastectomy is complex. Research suggests that fewer than half of women undergoing mastectomy have adequate knowledge and make treatment decisions that are concordant with their underlying values. This systematic review assesses the feasibility and efficacy (...) of preoperative decision aids (DAs) to improve the patient decision-making process for breast reconstruction.A systematic review was performed using PubMed, Ovid MEDLINE, EMBASE, CINAHL, and Cochrane Databases published prior to January 4, 2018. Studies that assessed the impact of a DA on patient decision making for breast reconstruction were identified. The effect of preoperative DAs on decisional conflict in randomized controlled trials (RCTs) was measured with inverse variance-weighted mean differences

2019 Medical Decision Making

11. Comorbidities and the decision to undergo or forego destination therapy left ventricular assist device implantation: An analysis from the Trial of a Shared Decision Support Intervention for Patients and their Caregivers Offered Destination Therapy for End (PubMed)

Comorbidities and the decision to undergo or forego destination therapy left ventricular assist device implantation: An analysis from the Trial of a Shared Decision Support Intervention for Patients and their Caregivers Offered Destination Therapy for End Patients considering destination therapy left ventricular assist devices (DT LVAD) often have high comorbid burden but the association between these comorbidities and post-decision outcomes is unknown.We included subjects in DECIDE-LVAD (...) younger regardless of LVAD implantation status. After adjusting for age, overall and amongst LVAD recipients, patients with ≥1 comorbidity had higher mean decision conflict at baseline (23.2 ± 1.5 vs. 17.4 ± 2.2), and at 6 months, higher stress (13.0 ± 0.6 vs. 10.4 ± 1.0) and struggle with illness (13.3 ± 0.4 vs. 11.1 ± 0.6) than those without comorbidities (P < .05). No difference was noted in decision regret, PHQ-2, EQ-VAS, acceptance of illness and survival overall and amongst LVAD recipients

2019 American Heart Journal

12. Additive Multicriteria Decision Analysis Models: Misleading Aids for Life-Critical Shared Decision Making. (PubMed)

Additive Multicriteria Decision Analysis Models: Misleading Aids for Life-Critical Shared Decision Making. Background. There is growing interest in multicriteria decision analysis (MCDA) for shared decision making (SDM). A distinguishing feature is that a preferred treatment should extend years of life and/or improve health-related quality of life (HRQL). Additive MCDA models are inadequate for the task. A plethora of MCDA models exist, each claiming that it can correctly solve real-world

2019 Medical Decision Making

13. Patient decision aids: a content analysis based on a decision tree structure. (PubMed)

Patient decision aids: a content analysis based on a decision tree structure. This paper presents the preliminary results of a decision-tree analysis of Patient Decision Aids (PDA). PDAs are online or offline tools used to structure health information, elicit relevant values and emphasize the decision as a process, in ways that help patients make more informed health decisions individually or with relevant others.Twenty PDAs are randomly selected from the International Patient Decision Aids (...) Standards (IPDAS) ( https://decisionaid.ohri.ca/AZlist.html ) approved list. An evaluation tool is built bottom-up and top-down and results are described in terms of communicating uncertainty, completeness of the decision tree, ambiguous or misleading phrasing, overall strategies suggested within personal stories.Twelve of the analyzed PDAs had branches of the decision tree which were not discussed in the tool and 6 had logically ambiguous phrasing. Many tools included dichotomous options, when

2019 Medical Informatics and Decision Making

14. Decision tree analysis in subarachnoid hemorrhage: prediction of outcome parameters during the course of aneurysmal subarachnoid hemorrhage using decision tree analysis. (Full text)

Decision tree analysis in subarachnoid hemorrhage: prediction of outcome parameters during the course of aneurysmal subarachnoid hemorrhage using decision tree analysis. OBJECTIVEThe aim of this study was to create prediction models for outcome parameters by decision tree analysis based on clinical and laboratory data in patients with aneurysmal subarachnoid hemorrhage (aSAH).METHODSThe database consisted of clinical and laboratory parameters of 548 patients with aSAH who were admitted (...) outcome at all time points had a prediction accuracy of 71.1% in the training data set, with procalcitonin on day 1 being the most important differentiating factor at all time points. A total of 148 patients (27%) developed VP shunt dependency. The most important differentiating factor was hyperglycemia on admission.CONCLUSIONSThe multiple variable analysis capability of decision trees enables exploration of dependent variables in the context of multiple changing influences over the course

2018 Journal of Neurosurgery PubMed

15. Interactivity in a Decision Aid: Findings From a Decision Aid to Technologically Enhance Shared Decision Making RCT

Interactivity in a Decision Aid: Findings From a Decision Aid to Technologically Enhance Shared Decision Making RCT Colorectal cancer screening (CRCS) remains underutilized. Decision aids (DAs) can increase patient knowledge, intent, and CRCS rates compared with "usual care," but whether interactivity further increases CRCS rate remains unknown.A two-armed RCT compared the effect of a web-based DA that interactively assessed patient CRC risk and clarified patient preference for specific CRCS (...) test to a web-based DA with the same content but without the interactive tools.The study sites were 12 community- and three university-based primary care practices (56 physicians) in southeastern Michigan. Participants were men and women aged 50-75 years not current on CRCS.Random allocation to interactive DA (interactive arm) or non-interactive DA (non-interactive arm).Primary outcome was medical record documentation of CRCS 6 months after the intervention. Secondary outcome was patient decision

2019 EvidenceUpdates

16. Multi-criteria decision analysis for the appraisal of medical needs: a pilot study

Multi-criteria decision analysis for the appraisal of medical needs: a pilot study 2016 www.kce.fgov.be KCE REPORT 272 MULTI-CRITERIA DECISION ANALYSIS FOR THE APPRAISAL OF MEDICAL NEEDS: A PILOT STUDY 2016 www.kce.fgov.be KCE REPORT 272 HEALTH SERVICES RESEARCH MULTI-CRITERIA DECISION ANALYSIS FOR THE APPRAISAL OF MEDICAL NEEDS: A PILOT STUDY IRINA CLEEMPUT, STEPHAN DEVRIESE, WENDY CHRISTIAENS, LAURENCE KOHN COLOPHON Title: Multi-criteria decision analysis for the appraisal of medical needs (...) /10.273/68 ISSN: 2466-6459 Copyright: KCE reports are published under a “by/nc/nd” Creative Commons Licence http://kce.fgov.be/content/about-copyrights-for-kce-reports. How to refer to this document? Cleemput I, Devriese S, Christiaens W, Kohn L. Multi-criteria decision analysis for the appraisal of medical needs: a pilot study. Health Services Research (HSR) Brussels: Belgian Health Care Knowledge Centre (KCE). 2016. KCE Reports 272. D/2016/10.273/68. This document is available on the website

2016 Belgian Health Care Knowledge Centre

17. Multi criteria decision analysis to select priority diseases for Newborn blood screening

Multi criteria decision analysis to select priority diseases for Newborn blood screening 2016 www.kce.fgov.be KCE REPORT 267Cs SYNTHESIS MULTI CRITERIA DECISION ANALYSIS TO SELECT PRIORITY DISEASES FOR NEWBORN BLOOD SCREENING 2016 www.kce.fgov.be KCE REPORT 267Cs HEALTH SERVICES RESEARCH SYNTHESIS MULTI CRITERIA DECISION ANALYSIS TO SELECT PRIORITY DISEASES FOR NEWBORN BLOOD SCREENING CHRIS DE LAET, GERMAINE HANQUET, ERIK HENDRICKX KCE Report 267Cs Newborn blood screening 1 ? FOREWORD In Europe (...) with different lists for each country or region, always with good reasons, but often conditionally and not always consistently. Here and there the idea is gaining ground that decisions like those on neonatal screening could be made in a more coherent way, and on this point we have found the example of Québec very inspiring. In the study in front of you, we have therefore attempted to evaluate the degree to which their model of multi-criteria decision analysis (MCDA) is applicable to Belgium (read

2016 Belgian Health Care Knowledge Centre

18. Systematic review with meta-analysis: Parenting concerns, parental identity and functional status influence medical treatment decisions of patients with advanced cancer

Systematic review with meta-analysis: Parenting concerns, parental identity and functional status influence medical treatment decisions of patients with advanced cancer Parenting concerns, parental identity and functional status influence medical treatment decisions of patients with advanced cancer | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about (...) decisions of patients with advanced cancer Article Text Nursing issues Systematic review with meta-analysis Parenting concerns, parental identity and functional status influence medical treatment decisions of patients with advanced cancer Free Carmen G Loiselle , Ariane Santerre-Theil Statistics from Altmetric.com Commentary on: Park EM, Check DK, Song MK, et al . Parenting while living with advanced cancer: A qualitative study. Palliat Med 2017;31:231–8. Implications for practice and research Parents

2017 Evidence-Based Nursing

19. Prediction of fetal growth restriction and complications: individual participant data (IPD) meta-analysis with decision curve analysis. International Prediction of Complications in Pregnancy: Fetal Growth restriction (IPPIC-FGR)

Prediction of fetal growth restriction and complications: individual participant data (IPD) meta-analysis with decision curve analysis. International Prediction of Complications in Pregnancy: Fetal Growth restriction (IPPIC-FGR) Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate (...) will be examined as potential source of heterogeneity: species (stratified per species); sex (stratified per sex); duration of index ischemia (linear); stem cell dose (linear); blinding of outcome assessment reported (stratified yes vs no). For stratified analyses, a minimum number of 8 studies per subgroup is required. ">Subgroup analyses A sensitivity analysis is conducted to assess the impact of decisions taken in the review process on the meta-analysis outcome. These decisions may have been made in various

2019 PROSPERO

20. Analysis of How Emergency Physicians' Decisions to Hospitalize or Discharge Patients With Acute Heart Failure Match the Clinical Risk Categories of the MEESSI-AHF Scale

Analysis of How Emergency Physicians' Decisions to Hospitalize or Discharge Patients With Acute Heart Failure Match the Clinical Risk Categories of the MEESSI-AHF Scale The Multiple Estimation of Risk Based on the Emergency Department Spanish Score in Patients With Acute Heart Failure (MEESSI-AHF) is a validated clinical decision tool that characterizes risk of mortality in emergency department (ED) acute heart failure patients. The objective of this study is to compare the distribution of risk (...) to determine the adjusted association between ED disposition decision and the outcomes among patients who were stratified into low- and increased-risk categories.We included 7,930 patients (80.5 years [SD 10.1 years]; women 54.7%; hospitalized 75.3%). Compared with that for low-risk MEESSI-AHF patients, odds ratios for hospitalization of patients in intermediate-, high-, and very-high-risk categories were 1.83 (95% confidence interval [CI] 1.64 to 2.05), 3.05 (95% CI 2.48 to 3.76), and 3.98 (95% CI 3.13

2019 EvidenceUpdates

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