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Mortality in Rheumatoid Arthritis (RA): factors associated with recording RA on deathcertificates. Deathcertificates can be used to assess disease prevalence and incidence; however, rheumatoid arthritis (RA) often remains unreported in deathcertificates. We sought to determine to what extent RA is underreported and what demographic and clinical characteristics could predict mention of RA in the death certificate.We recruited 1328 patients with RA from private, public and military (...) rheumatology practices and followed them prospectively for yearly evaluations. A rheumatologist assessed clinical characteristics of RA and comorbidities at each evaluation. Deaths were identified through family members, other physicians, obituaries and public death databases. All were confirmed with state-issued deathcertificates. Patients with and without RA in deathcertificate were compared using bivariate and multivariate analyses.By December 2013, 326 deaths had occurred. We received and reviewed
Restriction to period of interest improves informative value of deathcertificate only proportions in period analysis of cancer survival. The proportion of cases registered by deathcertificates only (DCO) is a widely used indicator for potential bias in cancer survival studies. Period analysis is increasingly used to derive up-to-date cancer survival estimates. We aimed to assess whether reported DCO proportions should be restricted to the specific recent calendar period ("restricted period (...) ") or refer to all diagnosis years of included patients ("full period").We assessed correlations of bias in period survival estimates resulting from DCO cases with DCO proportions in the restricted and full period, respectively. We used cancer registry data to simulate bias and DCO proportions resulting from various patterns of underreporting of deceased cases. We show results for six common cancers with very different prognosis and five different age groups.In all scenarios, the expected bias was highly
Issues using linkage of hospital records and deathcertificate data to determine the size of a potential palliative care population. Studies aiming to identify palliative care populations have used data from deathcertificates and in some cases hospital records. The size and characteristics of the identified populations can show considerable variation depending on the data sources used. It is important that service planners and researchers are aware of this.To illustrate the differences (...) in the size and characteristics of a potential palliative care population depending on the differential use of linked hospital records and deathcertificate data.Retrospective cohort study.The cohort consisted of 23,852 people aged 20 years and over who died in Western Australia between 1 January 2009 and 31 December 2010 after excluding deaths related to pregnancy or trauma. Within this cohort, the number, proportion and characteristics of people who died from one or more of 10 medical conditions
Association Between Occupational Exposures and Sarcoidosis: An Analysis From DeathCertificates in the United States, 1988-1999. Sarcoidosis is a disease that is associated with occupational and environmental antigens, in the setting of a susceptible host. The aim of this study was to examine the association between sarcoidosis mortality and previously reported occupational exposures based on sex and race.The decedents enrolled in this study were derived from United States deathcertificates (...) from 1988-1999. Cause of death was coded according to ICD-9 and ICD-10. The usual occupation was coded with Bureau of the Census Occupation Codes. Mortality odds ratio (MOR) were determined and multiple Poisson regression were performed to evaluate the independent exposure effects after adjustment for age, sex, race and other occupational exposures.Of the 7,118,535 decedents in our study, 3,393 were identified as sarcoidosis-related, including 1,579 identified as sarcoidosis being the underlying
Reporting of clinically diagnosed dementia on deathcertificates: retrospective cohort study. mortality statistics are a frequently used source of information on deaths in dementia but are limited by concerns over accuracy.to investigate the frequency with which clinically diagnosed dementia is recorded on deathcertificates, including predictive factors.a retrospective cohort study assembled using a large mental healthcare database in South London, linked to Office for National Statistics (...) mortality data. People with a clinical diagnosis of dementia, aged 65 or older, who died between 2006 and 2013 were included. The main outcome was deathcertificate recording of dementia.in total, 7,115 people were identified. Dementia was recorded on 3,815 (53.6%) deathcertificates. Frequency of dementia recording increased from 39.9% (2006) to 63.0% (2013) (odds ratio (OR) per year increment 1.11, 95% CI 1.07-1.15). Recording of dementia was more likely if people were older (OR per year increment
Disability-Adjusted Life Years (DALYs) for Injuries Using DeathCertificates and Hospital Discharge Survey by the Korean Burden of Disease Study 2012 A system for assessing the burdens imposed by disease and injury was developed to meet healthcare, priority setting, and policy planning needs. The first such system, the Global Burden of Disease (GBD), was implemented in 1990. However, problems associated with limited data and assumed disability weightings remain to be resolved. The purpose (...) of the present study was to estimate national burdens of injuries in Korea using more reliable data and disability weightings. The incidences of injuries were estimated using the Korean National Hospital Discharge Survey and the mortality data from the Korean National Statistical Office in 2010. Additionally, durations of injuries and age at injury onset were used to calculate disability-adjusted life years (DALY) using disability weightings derived from the Korean Burden of Disease (KBD) study. Korea had
Familial aggregation of Parkinson disease in Utah: A population-based analysis using deathcertificates To describe clustering of death from Parkinson disease (PD) in relatives in a large US study.We analyzed the Utah Population Database resource, which includes genealogy data of more than 2.7 million individuals linked to 519,061 individuals with a Utah deathcertificate (DC). We identified individuals whose DC included PD as a cause of death using ICD coding. In those individuals whose Utah (...) with a Utah DC (RR = 1.44, 95% CI 1.29-1.60) and among 93,398 third-degree relatives with a Utah DC (RR = 1.10, 95% CI 1.03-1.18).Significant evidence for excess familial clustering was observed for PD deaths. The excess familial clustering and the significantly elevated RRs for PD among close and distant relatives strongly support a genetic contribution to PD mortality. These results confirm and expand the results of previous studies of PD by quantifying the risk of PD death among more distant relatives.
Medical certificates of death: First principles and established practices provide answers to new questions 26668191 2016 05 16 2017 01 05 1488-2329 188 1 2016 Jan 05 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Medical certificates of death: First principles and established practices provide answers to new questions. 49-52 10.1503/cmaj.151130 Downie Jocelyn J Faculty of Law (Downie, Oliver) and Faculty of Medicine (Downie), Dalhousie University (...) , Halifax, NS firstname.lastname@example.org. Oliver Kacie K Faculty of Law (Downie, Oliver) and Faculty of Medicine (Downie), Dalhousie University, Halifax, NS. eng Journal Article 2015 12 14 Canada CMAJ 9711805 0820-3946 AIM IM Canada Cause of DeathDeathCertificates Humans Practice Patterns, Physicians' Suicide, Assisted 2015 12 16 6 0 2015 12 17 6 0 2016 5 18 6 0 ppublish 26668191 cmaj.151130 10.1503/cmaj.151130 PMC4695354
Automatic ICD-10 classification of cancers from free-text deathcertificates. Deathcertificates provide an invaluable source for cancer mortality statistics; however, this value can only be realised if accurate, quantitative data can be extracted from certificates--an aim hampered by both the volume and variable nature of certificates written in natural language. This paper proposes an automatic classification system for identifying cancer related causes of death from death (...) certificates.Detailed features, including terms, n-grams and SNOMED CT concepts were extracted from a collection of 447,336 deathcertificates. These features were used to train Support Vector Machine classifiers (one classifier for each cancer type). The classifiers were deployed in a cascaded architecture: the first level identified the presence of cancer (i.e., binary cancer/nocancer) and the second level identified the type of cancer (according to the ICD-10 classification system). A held-out test set was used
Automatic classification of diseases from free-text deathcertificates for real-time surveillance Deathcertificates provide an invaluable source for mortality statistics which can be used for surveillance and early warnings of increases in disease activity and to support the development and monitoring of prevention or response strategies. However, their value can be realised only if accurate, quantitative data can be extracted from deathcertificates, an aim hampered by both the volume (...) and variable nature of certificates written in natural language. This study aims to develop a set of machine learning and rule-based methods to automatically classify deathcertificates according to four high impact diseases of interest: diabetes, influenza, pneumonia and HIV.Two classification methods are presented: i) a machine learning approach, where detailed features (terms, term n-grams and SNOMED CT concepts) are extracted from deathcertificates and used to train a set of supervised machine
Certification of Coroners cases by pathologists would improve the completeness of death registration in Jamaica. Describe the completeness and quality of Jamaica's 2008 vital registration mortality database.Multiple sources (hospitals, police, forensic pathologists, Coroners courts) were used to validate deaths registered as occurring in 2008. A 10% random sample was examined to evaluate the quality of certification and coding. Jamaica, a middle-income country of 2.7 million, began vital (...) percent were coded to ill-defined causes of death. Recoding the sample increased mortality from prematurity, pregnancy complications, homicide, selected cardiovascular disorders, and human immunodeficiency virus/AIDS.Delays registering Coroners cases, certification and coding errors, introduced biases into the disease profile limiting the data's value in informing clinical care. Issuance of medical certificates by pathologists who investigate Coroners cases and training physicians and coders would
certificates with medical cause, medical records and interviews with household members and relatives to ascertain a pregnancy-related or maternal death. An External Expert Committee reviewed the information collected to assign a cause for each death. Our results were compared to those reported in the same period by the MDSS.Our study identified 690 deaths of WRA and 69 maternal deaths of which 34.8% occurred outside health facilities. The MDSS recorded during the study period 538 deaths of WRA and 29 (...) maternal deaths (including only one outside health facility) representing respectively an underreporting of 22.0% and 58.0%. Late maternal deaths represented 11.4% of all deaths of women with a registered pregnancy within 12 months prior to the death, while the MDSS identified none. The maternal mortality ratio (MMR) was estimated at 103, approximately 2.5 times higher than that reported in the MDSS.Our study has shown weaknesses in the current notification system for maternal deaths in the region
of sudden cardiac death AHA 2016 Optimal implantable cardioverter defibrillator programming and testing HRS/EHRA/APHRS/SOLAECE 2016 Treatment of cardiac arrest: current status and future directions: strategies to improve cardiac arrest survival IOM 2015 Eligibility and disqualification recommendations for competitive athletes with cardiovascular abnormalities ACC/AHA 2015 Ventricular arrhythmias EHRA/HRS/APHRS 2014 Arrhythmias in adult congenital heart disease PACES/HRS 2014 Implantable cardioverter (...) as the presence of at least 1 PVC on a 12-lead ECG or >30 PVCs per hour, are associated with increased cardiovascular risk and increased mortality. In a study from Taiwan of patients without sustained VT or structural heart disease who had 24-hour Holter monitoring for clinical evaluation, multifocal PVCs were associated with increased risk of death and nonfatal cardiovascular adverse outcomes. In the same population, nonsustained ventricular tachycardia (NSVT) was independently associated with increased risk
antiarrhythmic medications (eg, flecainide, encainide, moricizine) increased the risk of death despite suppression of VA. , Treatment of PVCs with antiarrhythmic medications has not been shown to reduce mortality and, in the post-MI population, treatment with class I sodium channel–blocking medications (eg, quinidine, flecainide) increases the risk of death. , Likewise, in patients with a reduced LVEF class I, sodium channel–blocking medications and d-sotalol increase the risk of death. , Beta blockers (...) extrapolation of data from specific local programs, while the highest rates included noncardiac causes of sudden death such as pulmonary embolism or intracranial bleeding. The mid-range numbers were largely based on deathcertificate studies that required a code inclusive of ischemic heart disease. The 2017 update of cardiovascular statistics from the AHA estimated the total annual burden of out-of-hospital cardiac arrest at 356 500. An additional 209 000 in-hospital cardiac arrests occur annually. Among
) in South Dublin and Wicklow . Seizure 1998 ; 7: 355 – 358 . | | 9. Langan, Y , Nashef, L , Sander, JW . Certification of deaths attributable to epilepsy . J Neurol Neurosurg Psychiatry 2002 ; 73: 751 – 752 . | | 10. Edey, S , Moran, N , Nashef, L. SUDEP and epilepsy-related mortality in pregnancy . Epilepsia 2014 ; 55: e72 – e74 . | | 11. Ackers, R , Besag, FM , Hughes, E , Squier, W , Murray, ML , Wong, IC . Mortality rates and causes of death in children with epilepsy prescribed antiepileptic drugs (...) to help determine, and document on deathcertificates, the etiology in individuals, and in order to improve overall knowledge of this condition. Research to identify preventable risk factors should be supported and encouraged so that future clinical trials will be conducted to reduce SUDEP occurrence. Of particular importance is to better understand (a) the relationship between the nature, severity, and duration of epilepsy and the occurrence of SUDEP, and (b) whether current treatments affect
Measuring Childbirth Outcomes Using Administrative and Birth Certificate Data. Maternal complications during and after childbirth demonstrate wide variation across hospitalsNational reporting systems do not integrate maternal and newborn outcomes when defining hospital obstetric care quality WHAT THIS ARTICLE TELLS US THAT IS NEW: Administrative data can be used to calculate hospital-level risk-adjusted maternal, newborn, and composite maternal-newborn performanceMaternal and newborn hospital (...) performance were poorly correlated, suggesting that composite performance measures must also report underlying maternal and newborn performance separately BACKGROUND:: The number of pregnancy-related deaths and severe maternal complications continues to rise in the United States, and the quality of obstetrical care across U.S. hospitals is uneven. Providing hospitals with performance feedback may help reduce the rates of severe complications in mothers and their newborns. The aim of this study
mortality and patient satisfaction. Fifty-four findings related to nurse outcomes with the sub-categories: personal and professional factors, knowledge and skills, organizational commitment, job satisfaction, empowerment and confidence. Six findings related to organizational benefits: including the sub-categories of nursing turnover and vacancy rates, perception of healthcare, and costs to the organization.The current model risks driving further proliferation of specialty certifications and certifying (...) The relationship between specialty nurse certification and patient, nurse and organizational outcomes: A systematic review. To review the current evidence on the relationship between specialty nurse certification and outcomes.A structured and comprehensive systematic review was undertaken using the Joanna Briggs Institute framework to include both published research studies and expert opinion papers.Four electronic databases CINAHL, MEDLINE, PubMed, and PsychINFO were searched between 2000
. Deaths are dichotomous outcomes. You are either dead or alive, there is no in-between. Of course, you can die for a variety of causes, often more than one cause at a time. The death registration certificate, refined since ’s days, could be wrong or based on uncertain information. The certificates could also be late, creating artefacts such as “parcelling” when a stack of delayed death notifications lands on the desk of an analyst all in one go. However, mortality does not lie, it is not open (...) COVID-19 – Tracking European Mortality COVID-19 - Tracking European Mortality - CEBM CEBM The Centre for Evidence-Based Medicine develops, promotes and disseminates better evidence for healthcare. Navigate this website COVID-19 – Tracking European Mortality April 20, 2020 Tom Jefferson, Carl Heneghan When Dr John Snow investigated the 1854 cholera outbreak around London, he made a first basic decision on the type of evidence he was going to look at – deaths. Deaths have a great advantage
Automated versus physician assignment of cause of death for verbal autopsies: randomized trial of 9374 deaths in 117 villages in India. Verbal autopsies with physician assignment of cause of death (COD) are commonly used in settings where medical certification of deaths is uncommon. It remains unanswered if automated algorithms can replace physician assignment.We randomized verbal autopsy interviews for deaths in 117 villages in rural India to either physician or automated COD assignment (...) require further development and rigorous evaluation. Lay reporting of deaths paired with physician COD assignment of verbal autopsies, despite some limitations, remains a practicable method to document the patterns of mortality reliably for unattended deaths.ClinicalTrials.gov , NCT02810366. Submitted on 11 April 2016.