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61. Familial aggregation of Parkinson disease in Utah: A population-based analysis using death certificates Full Text available with Trip Pro

Familial aggregation of Parkinson disease in Utah: A population-based analysis using death certificates To describe clustering of death from Parkinson disease (PD) in relatives in a large US study.We analyzed the Utah Population Database resource, which includes genealogy data of more than 2.7 million individuals linked to 519,061 individuals with a Utah death certificate (DC). We identified individuals whose DC included PD as a cause of death using ICD coding. In those individuals whose Utah (...) with a Utah DC (RR = 1.44, 95% CI 1.29-1.60) and among 93,398 third-degree relatives with a Utah DC (RR = 1.10, 95% CI 1.03-1.18).Significant evidence for excess familial clustering was observed for PD deaths. The excess familial clustering and the significantly elevated RRs for PD among close and distant relatives strongly support a genetic contribution to PD mortality. These results confirm and expand the results of previous studies of PD by quantifying the risk of PD death among more distant relatives.

2016 Neurology: Genetics

62. Disability-Adjusted Life Years (DALYs) for Injuries Using Death Certificates and Hospital Discharge Survey by the Korean Burden of Disease Study 2012 Full Text available with Trip Pro

Disability-Adjusted Life Years (DALYs) for Injuries Using Death Certificates and Hospital Discharge Survey by the Korean Burden of Disease Study 2012 A system for assessing the burdens imposed by disease and injury was developed to meet healthcare, priority setting, and policy planning needs. The first such system, the Global Burden of Disease (GBD), was implemented in 1990. However, problems associated with limited data and assumed disability weightings remain to be resolved. The purpose (...) of the present study was to estimate national burdens of injuries in Korea using more reliable data and disability weightings. The incidences of injuries were estimated using the Korean National Hospital Discharge Survey and the mortality data from the Korean National Statistical Office in 2010. Additionally, durations of injuries and age at injury onset were used to calculate disability-adjusted life years (DALY) using disability weightings derived from the Korean Burden of Disease (KBD) study. Korea had

2016 Journal of Korean medical science

63. Medical certificates of death: First principles and established practices provide answers to new questions Full Text available with Trip Pro

Medical certificates of death: First principles and established practices provide answers to new questions 26668191 2016 05 16 2017 01 05 1488-2329 188 1 2016 Jan 05 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Medical certificates of death: First principles and established practices provide answers to new questions. 49-52 10.1503/cmaj.151130 Downie Jocelyn J Faculty of Law (Downie, Oliver) and Faculty of Medicine (Downie), Dalhousie University (...) , Halifax, NS jocelyn.downie@dal.ca. Oliver Kacie K Faculty of Law (Downie, Oliver) and Faculty of Medicine (Downie), Dalhousie University, Halifax, NS. eng Journal Article 2015 12 14 Canada CMAJ 9711805 0820-3946 AIM IM Canada Cause of Death Death Certificates Humans Practice Patterns, Physicians' Suicide, Assisted 2015 12 16 6 0 2015 12 17 6 0 2016 5 18 6 0 ppublish 26668191 cmaj.151130 10.1503/cmaj.151130 PMC4695354

2016 CMAJ : Canadian Medical Association Journal

64. Association Between Occupational Exposures and Sarcoidosis: An Analysis From Death Certificates in the United States, 1988-1999. Full Text available with Trip Pro

Association Between Occupational Exposures and Sarcoidosis: An Analysis From Death Certificates in the United States, 1988-1999. Sarcoidosis is a disease that is associated with occupational and environmental antigens, in the setting of a susceptible host. The aim of this study was to examine the association between sarcoidosis mortality and previously reported occupational exposures based on sex and race.The decedents enrolled in this study were derived from United States death certificates (...) from 1988-1999. Cause of death was coded according to ICD-9 and ICD-10. The usual occupation was coded with Bureau of the Census Occupation Codes. Mortality odds ratio (MOR) were determined and multiple Poisson regression were performed to evaluate the independent exposure effects after adjustment for age, sex, race and other occupational exposures.Of the 7,118,535 decedents in our study, 3,393 were identified as sarcoidosis-related, including 1,579 identified as sarcoidosis being the underlying

2016 Chest

65. Reporting of clinically diagnosed dementia on death certificates: retrospective cohort study. Full Text available with Trip Pro

Reporting of clinically diagnosed dementia on death certificates: retrospective cohort study. mortality statistics are a frequently used source of information on deaths in dementia but are limited by concerns over accuracy.to investigate the frequency with which clinically diagnosed dementia is recorded on death certificates, including predictive factors.a retrospective cohort study assembled using a large mental healthcare database in South London, linked to Office for National Statistics (...) mortality data. People with a clinical diagnosis of dementia, aged 65 or older, who died between 2006 and 2013 were included. The main outcome was death certificate recording of dementia.in total, 7,115 people were identified. Dementia was recorded on 3,815 (53.6%) death certificates. Frequency of dementia recording increased from 39.9% (2006) to 63.0% (2013) (odds ratio (OR) per year increment 1.11, 95% CI 1.07-1.15). Recording of dementia was more likely if people were older (OR per year increment

2016 Age and ageing

66. Issues using linkage of hospital records and death certificate data to determine the size of a potential palliative care population. Full Text available with Trip Pro

Issues using linkage of hospital records and death certificate data to determine the size of a potential palliative care population. Studies aiming to identify palliative care populations have used data from death certificates and in some cases hospital records. The size and characteristics of the identified populations can show considerable variation depending on the data sources used. It is important that service planners and researchers are aware of this.To illustrate the differences (...) in the size and characteristics of a potential palliative care population depending on the differential use of linked hospital records and death certificate data.Retrospective cohort study.The cohort consisted of 23,852 people aged 20 years and over who died in Western Australia between 1 January 2009 and 31 December 2010 after excluding deaths related to pregnancy or trauma. Within this cohort, the number, proportion and characteristics of people who died from one or more of 10 medical conditions

2016 Palliative medicine

67. Certificate of need laws: a systematic review and cost-effectiveness analysis. Full Text available with Trip Pro

Certificate of need laws: a systematic review and cost-effectiveness analysis. Certificate of Need (CON) laws, currently in place in 35 US states, require certain health care providers to obtain a certification of their economic necessity from a state board before opening or undertaking a major expansion. We conduct the first systematic review and cost-effectiveness analysis of these laws.We review 90 articles to summarize the evidence on how certificate of need laws affect regulatory costs (...) , health expenditures, health outcomes, and access to care. We use the findings from the systematic review to conduct a cost-effectiveness analysis of CON.The literature provides mixed results, on average finding that CON increases health expenditures and overall elderly mortality while reducing heart surgery mortality. Our cost-effectiveness analysis estimates that the costs of CON laws somewhat exceed their benefits, although our estimates are quite uncertain.The literature has not yet reached

2020 BMC health services research

68. Excess winter deaths and illness and the health risks associated with cold homes

certificates). Ensure any relevant problems are addressed. [1] Although lower temperatures have a more significant effect on health, the ill effects from cold homes are seen when outdoor temperatures drop to around 6°C. Because temperatures in this range are much more common, this is when the greatest number of health problems caused by the cold occur. Excess winter deaths and illness and the health risks associated with cold homes (NG6) © NICE 2019. All rights reserved. Subject to Notice of rights (https (...) . This represented the lowest figure since 1950/51 and reflects a prolonged period of milder than average weather after November 2013. The 5-year moving average shows a decreasing trend in recent years up to 2005/06, after which there has been a gradual rise (Statistical bulletin: excess winter mortality in England and Wales, 2013/14 Office for National Statistics). It is too early to tell whether the low figures for 2013/14 represent a new downward trend. Most excess winter deaths and illnesses are not caused

2015 National Institute for Health and Clinical Excellence - Clinical Guidelines

69. Sudden cardiac death among persons with diabetes aged 1-49 years: a 10-year nationwide study of 14 294 deaths in Denmark. Full Text available with Trip Pro

Danish death certificates, 1698 cases of sudden and unexpected death were identified. Through review of autopsy reports, discharge summaries, and the Danish registries, we identified 1363 cases of SCD. The Danish Register of Medicinal Product Statistics was used to identify persons with type 1 DM and type 2 DM. Among the 14 294 decedents, there were 669 with DM, of which 118 suffered SCD (9% of all SCD), making SCD the leading cause of death among young persons with DM. Among those aged 1-35 years (...) Sudden cardiac death among persons with diabetes aged 1-49 years: a 10-year nationwide study of 14 294 deaths in Denmark. The aim of this study was to compare nationwide incidence rate (IR) of sudden cardiac death (SCD) in persons aged 1-49 years with and without diabetes mellitus (DM).The study population consisted of all persons in Denmark aged 1-49 years in 2000-09, which equals 27.1 million person-years. All 14 294 deaths in the 10-year period were included. By using the highly descriptive

2020 European Heart Journal

70. Canadian guidelines for controlled pediatric donation after circulatory determination of death-summary report Full Text available with Trip Pro

or hospital practices, policies, and guidelines. 21) The critical care team must be responsible for patient management between the decision to WLST and the determination of death. 22) The ODO, organ recovery, and transplant team must not be involved in any aspect of management of the dying process. 23) WLST may occur in the critical care unit, near the operating room, or in the operating room, as determined by surrogate decision makers’ preferences, institutional logistics, resources, and facilities. 24 (...) physicians must confirm their determinations concurrently at the end of a hands-off period of observation during circulatory arrest. 32) No physician who has active involvement in transplant procedures or allocation of donated organs shall take any part in donor death determination. 33) The minimum level of physician qualification required to determine death in pDCD is as follows: a) They possess the requisite skills and training. A particular level of specialty certification is not required, but skills

2017 CPG Infobase

71. Mortality rates and the causes of death related to diabetes mellitus in Shanghai Songjiang District: an 11-year retrospective analysis of death certificates. Full Text available with Trip Pro

Mortality rates and the causes of death related to diabetes mellitus in Shanghai Songjiang District: an 11-year retrospective analysis of death certificates. China is one of the countries with the highest prevalence of diabetes in the world. We analysed all the death certificates mentioning diabetes from 2002 to 2012 in Songjiang District of Shanghai to estimate morality rates and examine cause of death patterns.Mortality data of 2654 diabetics were collected from the database of local CDC (...) . The data set comprises all causes of death, contributing causes and the underlying cause, thereby the mortality rates of diabetes and its specified complications were analysed.The leading underlying causes of death were various cardiovascular diseases (CVD), which collectively accounted for about 30% of the collected death certificates. Diabetes was determined as the underlying cause of death on 28.7%. The trends in mortality showed that the diabetes related death rate increased about 1.78 fold

2015 BMC Endocrine Disorders

72. COVID-19 – Tracking European Mortality

. Deaths are dichotomous outcomes. You are either dead or alive, there is no in-between. Of course, you can die for a variety of causes, often more than one cause at a time. The death registration certificate, refined since ’s days, could be wrong or based on uncertain information. The certificates could also be late, creating artefacts such as “parcelling” when a stack of delayed death notifications lands on the desk of an analyst all in one go. However, mortality does not lie, it is not open (...) COVID-19 – Tracking European Mortality COVID-19 - Tracking European Mortality - CEBM CEBM The Centre for Evidence-Based Medicine develops, promotes and disseminates better evidence for healthcare. Navigate this website COVID-19 – Tracking European Mortality April 20, 2020 Tom Jefferson, Carl Heneghan When Dr John Snow investigated the 1854 cholera outbreak around London, he made a first basic decision on the type of evidence he was going to look at – deaths. Deaths have a great advantage

2020 Oxford COVID-19 Evidence Service

73. Ultralong Versus Standard Long Peripheral Intravenous Catheters: A Randomized Controlled Trial of Ultrasonographically Guided Catheter Survival

Ultralong Versus Standard Long Peripheral Intravenous Catheters: A Randomized Controlled Trial of Ultrasonographically Guided Catheter Survival CRITICAL REVIEW FORM: THERAPY ARTICLES Resident: Dylan Woolum Date: 05/15/20 Citation: Bahl A et al. Ultralong Versus Standard Long Peripheral Intravenous Catheters: A Randomized Controlled Trial of Ultrasonographically Guided Catheter Survival. Ann Emerg Med 2020. PMID: 31955940 Study Objective: To compare survival of ultralong ultrasound guided PIV (...) compared with a standard long one. Study Methodology: (design, inclusion and exclusion criteria, interventions compared, outcomes evaluated) Single site, U.S. prospective non-blinded 2-arm RCT. Patients randomized to either standard long catheter (20 gauge, 4.78 cm Becton Dickinson Insyte Autoguard) or ultralong catheter (20 gauge, 6.35 cm B. Braun Introcan Safety IV). Cohort of trained ED attendings, residents, APPs, nurses, and technicians who had completed certification (2-hour vascular access

2020 Emergency Medicine Journal Club

74. Assessing the risk of maternal morbidity and mortality Full Text available with Trip Pro

Between 1999 and 2014, the national prevalence of opiate use disorder at delivery more than quadrupled, increasing from 1.5 to 6.5 cases per 1000 delivery hospitalizations. Haight S.C. Ko J.Y. Tong V.T. Bohm M.K. Callaghan W.M. Opioid use disorder documented at delivery hospitalization - United States, 1999-2014. MMWR Morb Mortal Wkly Rep. 2018; 67 : 845-849 A recent study using maternal death certificate data from 22 states demonstrated a doubling in pregnancy-associated mortality involving opiates (...) Introduction The rates of maternal morbidity and mortality in the United States are unacceptably high. Centers for Disease Control and Prevention Rates in severe morbidity indicators per 10,000 delivery hospitalizations, 1993–2014 rates. Date: 2017 Date accessed: January 3, 2021 , Petersen E.E. Davis N.L. Goodman D. et al. Vital signs: pregnancy-related deaths, United States, 2011-2015, and strategies for prevention, 13 states, 2013-2017. MMWR Morb Mortal Wkly Rep. 2019; 68 : 423-429 Reducing the number

2021 Society for Maternal-Fetal Medicine

75. Impact of Stroke Center Certification on Mortality After Ischemic Stroke: The Medicare Cohort From 2009 to 2013. Full Text available with Trip Pro

Impact of Stroke Center Certification on Mortality After Ischemic Stroke: The Medicare Cohort From 2009 to 2013. An increasing number of hospitals have been certified as primary stroke centers (PSCs). It remains unknown whether the action toward PSC certification has improved the outcome of stroke care. This study aimed to understand whether PSC certification reduced stroke mortality.We examined Medicare fee-for-service beneficiaries aged ≥65 years who were hospitalized between 2009 and 2013 (...) for ischemic stroke. Hospitals were classified into 3 groups: new PSCs, the hospitals that received initial PSC certification between 2009 and 2013 (n=634); existing PSCs, the PSCs certified before 2009 (n=785); and non-SCs, the hospitals that have never been certified as PSCs (n=2640). Multivariate logistic regression and Cox proportional hazards model was used to compare the mortality among the 3 groups.Existing PSCs were significantly larger than new PSCs as reflected by total number of beds and annual

2017 Stroke

76. Measuring Childbirth Outcomes Using Administrative and Birth Certificate Data. Full Text available with Trip Pro

Measuring Childbirth Outcomes Using Administrative and Birth Certificate Data. Maternal complications during and after childbirth demonstrate wide variation across hospitalsNational reporting systems do not integrate maternal and newborn outcomes when defining hospital obstetric care quality WHAT THIS ARTICLE TELLS US THAT IS NEW: Administrative data can be used to calculate hospital-level risk-adjusted maternal, newborn, and composite maternal-newborn performanceMaternal and newborn hospital (...) performance were poorly correlated, suggesting that composite performance measures must also report underlying maternal and newborn performance separately BACKGROUND:: The number of pregnancy-related deaths and severe maternal complications continues to rise in the United States, and the quality of obstetrical care across U.S. hospitals is uneven. Providing hospitals with performance feedback may help reduce the rates of severe complications in mothers and their newborns. The aim of this study

2019 Anesthesiology

77. International study of the place of death of people with cancer: a population-level comparison of 14 countries across 4 continents using death certificate data. Full Text available with Trip Pro

International study of the place of death of people with cancer: a population-level comparison of 14 countries across 4 continents using death certificate data. Where people die can influence a number of indicators of the quality of dying. We aimed to describe the place of death of people with cancer and its associations with clinical, socio-demographic and healthcare supply characteristics in 14 countries.Cross-sectional study using death certificate data for all deaths from cancer (ICD-10 (...) codes C00-C97) in 2008 in Belgium, Canada, Czech Republic, England, France, Hungary, Italy, Mexico, the Netherlands, New Zealand, South Korea, Spain (2010), USA (2007) and Wales (N=1,355,910). Multivariable logistic regression analyses evaluated factors associated with home death within countries and differences across countries.Between 12% (South Korea) and 57% (Mexico) of cancer deaths occurred at home; between 26% (Netherlands, New Zealand) and 87% (South Korea) occurred in hospital. The large

2015 British Journal of Cancer

78. Errors in cause-of-death statement on death certificates in intensive care unit of Kathmandu, Nepal. Full Text available with Trip Pro

Errors in cause-of-death statement on death certificates in intensive care unit of Kathmandu, Nepal. Death certificates (DC) are one of the most important medico-legal documents that physicians work through. DCs are extensively used in health statistics for epidemiological studies, and in health policy planning as a public health resource tool. Cause-of-death (COD) statement, which is vulnerable to various errors, is the vital part of a DC that has the potential to mislead the policy makers (...) for the major medical errors.The study found errors in 78.4 % of DCs. The highest number of errors was in UCOD (83 %). Most common errors were "Mechanism of Death- terminal event" in ICOD, "More than one competing causes" in UCOD, and "OSC present but not listed" in OSC. The error in DC was found to be statistically significant with the severity of sepsis (p = 0.003), and presence of chronic organ failures (p = 0.034). Age, time of death, source of admission, and duration of ICU stay were not found

2015 BMC health services research

79. Guidelines on autopsy practice: Sudden death with likely cardiac pathology

to address the needs of the autopsy pathologist dealing with deaths reflecting cardiac disease, and indicates a technical approach and investigations that should prevent criticism of case analysis in medicolegal environments. It should also serve to protect the needs of the living (i.e. surviving siblings and relatives with genetic conditions) as well as society in general. The limitations of local Coronial practice and permissions are often unique to different cases and various parts of the UK (...) disease is related to illicit activity (e.g. drug taking). [Level of evidence: Grade D – the evidence has been taken from reviews of various texts/case reports and other presented cases, in medical and legal settings.] 3 Other (not primarily cardiac) pathology to be considered at the autopsy Many cases of apparent sudden ‘cardiac’ death have no relevance to myocardial disorders. Indeed, fatal non-cardiac pathology (with cardiac-like symptoms) may be often encountered: ? pulmonary embolism ? pneumonia

2017 Royal College of Pathologists

80. Guidelines on autopsy practice: Industrial/occupational-related lung disease deaths including asbestos

and pathologists in training, particularly those approaching the Certificate of Higher Autopsy Training (CHAT) examination and the FRCPath Part 2 in Forensic Pathology. The recommendations will also be of value to coroners to assist with inquests and solicitors handling personal injury claims in potential industrial-related deaths. 2 Role of the autopsy · To describe and diagnose all occupational/industrial disease manifestations · To determine the aetiology · To determine the extent and severity of any other (...) Guidelines on autopsy practice: Industrial/occupational-related lung disease deaths including asbestos CEff 290617 1 V2 Final Guidelines on autopsy practice Industrial/occupational-related lung disease deaths including asbestos June 2017 Series authors: Dr Michael Osborn, Imperial College Healthcare NHS Trust Professor Jim Lowe, Nottingham University Hospitals NHS Trust Specialist authors: Dr Richard Attanoos, Cardiff & Vale University Health Board and Cardiff University Dr Allen Gibbs, Cardiff

2017 Royal College of Pathologists

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