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161. Benign Prostatic Hyperplasia: Surgical Management of Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms

of substances with diuretic properties) or pharmacological management are either inadequate or inappropriate, warranting consideration of one of the many invasive procedures available for the treatment of LUTS attributed to BPH. Indications for the use of one of these modalities may include a desire by the patient to avoid taking a daily medication, failure of medical therapy to sufficiently ameliorate bothersome LUTS, and certain conditions that require more aggressive intervention where medical therapy (...) making approach to reach a treatment choice, which may necessitate a referral to another clinician for the chosen treatment. In all instances, patients should be provided with the risk/benefit profile for all treatment options in light of their circumstances to allow them to make informed decisions regarding their treatment plans. GUIDELINE STATEMENTS EVALUATION AND PEROPERATIVE TESTING 1. Clinicians should take a medical history and utilize the AUA-Symptom Index (AUA-SI) and urinalysis

2019 American Urological Association

162. Incontinence after Prostate Treatment

and extended survivorship. Practitioners benefit from being able to assess which patient will likely expe- rience further symptom recovery versus those who will not. This allows clinicians to set clear and reason- able expectations regarding the short-, medium-, and long-term sequela of IPT. Although most clinicians are familiar with the more commonly known term “post-prostatectomy inconti- nence,” this guideline uses the term IPT, which is more inclusive given that it covers the management of patients who (...) clinicians for which there may or may not be evidence in the medical literature Expert Opinion A statement, achieved by consensus of the Panel, that is based on members clinical training, experience, knowledge, and judgment for which there is no evidence 8 AUA and SUFU as well as external content experts. Additionally, a call for reviewers was placed on the AUA website from January 14-28, 2019 to allow any additional interested parties to request a copy of the document for review. The guideline was also

2019 American Urological Association

163. Treatment of Diabetes in Older Adults

treatment of hyperglycemia. (1|⊕⊕⊕⊕) Nutrition 4.4 In patients aged 65 years and older with diabetes, we recommend assessing nutritional status to detect and manage malnutrition. (1|⊕⊕⊕⊕) Technical remark: Nutritional status can be assessed using validated tools such as the Mini Nutritional Assessment and Short Nutritional Assessment Questionnaire. 4.5 In patients aged 65 years and older with diabetes and frailty, we suggest the use of diets rich in protein and energy to prevent malnutrition and weight (...) for progression to diabetes and development of CVDs; ( ) lists the ADA criteria for prediabetes and diabetes. The fasting plasma glucose and HbA1c categories allow easy identification of both diabetes and prediabetes. However, many people over the age of 60 years affected with diabetes and prediabetes are not diagnosed unless an oral glucose tolerance test is performed ( ). Importantly, individuals with prediabetes are at increased risk for progression to diabetes and development of CVDs. Population screening

2019 The Endocrine Society

164. Management of symptomatic hypermobility in children and young people

assessment will allow the OT to identify barriers to occupational performance and design the most appropriate intervention to maximise function. The main aim of OT intervention is to promote self- management where possible and this can be achieved through a variety of means. Assessment must be age and developmentally appropriate and tailored to the CYP’s individual needs. Activities of daily living Advice, education, strategies, functional goals, hand and shoulder exercise and small aids can improve CYP (...) ? Encouragement to maintain a healthy lifestyle, maintain hydration, eat a well- balanced diet, participate in regular gentle exercise, participate fully in school, activities and social events, and to get quality sleep are important ? Children and young people may benefit from joint protection advice and energy conservation principles for carrying out everyday tasks, to avoid placing unnecessary strain on their joints and minimising pain. Often encouragement is needed to include appropriate exercise

2019 British Society for Rheumatology

165. What is the evidence on the role of the arts in improving health and well-being? A scoping review

and textiles); • literature (e.g. writing, reading and attending literary festivals); • culture (e.g. going to museums, galleries, art exhibitions, concerts, the theatre, community events, cultural festivals and fairs); and • online, digital and electronic arts (e.g. animations, film-making and computer graphics). These categories combine both active and receptive engagement and, importantly, also transcend cultural boundaries and contain flexibility to allow new art forms to develop (as evidenced (...) in the development of online, digital and electronic arts over recent years). For the purposes of this review, this conceptual definition of art (combining common attributes but allowing fluidity in categorization) is followed. While there are other activities that fulfil many of the categories listed above (e.g. gardening, cooking and volunteering), consensus research has suggested these may be seen as creative but are not generally considered as arts, particularly when cross-referenced with definitions from

2019 WHO Health Evidence Network

166. Primary Prevention of ASCVD and T2DM in Patients at Metabolic Risk

activity behavioral counseling programs. For the primary prevention of ASCVD and T2DM, the Writing Committee recommends lifestyle management be the first priority. Behavioral programs should include a heart-healthy dietary pattern and sodium restriction, as well as an active lifestyle with daily walking, limited sedentary time, and a structured program of physical activity, if appropriate. Individuals with excess weight should aim for loss of ≥5% of initial body weight in the first year. Behavior (...) |⊕⊕⊕○) Technical remark: Providers can offer dietary recommendations based on common components of healthy cardiovascular dietary patterns to all individuals at metabolic risk. Specific dietary changes according to individual risk profiles could be supported with the help of a nutrition specialist in addition to the primary care provider. 2.4 In individuals at metabolic risk, we recommend prescribing daily physical activity, such as brisk walking, and reduction in sedentary time. (1|⊕⊕⊕○) Technical remark

2019 The Endocrine Society

167. Ustekinumab for the treatment of adult patients with moderately to severely active ulcerative colitis (UC)

Advanced therapy medicinal product BF Biologic failure BID Twice daily CD Crohn’s disease CI Confidence interval CrI Credible interval CRP C-reactive protein CSR Clinical study report CTR Clinical trial register DIC Deviance information criterion ECCO European Crohn's and Colitis Organisation EL Evidence level EMA European Medicines Agency EOW Every other week EQ-5D EuroQol Questionnaire 5 Dimensions EQ-VAS EuroQol Visual Analogue Scale GOL Golimumab GRADE Grading of Recommendations, Assessment (...) states that it is indicated for patients for whom a previous TNFi has failed, while for tofacitinib any prior biologic therapy is allowed. Objective and scope Objective The aim of this EUnetHTA Joint Relative Effectiveness Assessment is to compare the clinical effectiveness and safety of ustekinumab in the target patient populations with relevant compara- tors. The target patient populations and relevant comparators (according to the requirements of the EUnetHTA partners) are defined in the project

2019 EUnetHTA

168. Renal Transplantation

. Everolimus with Reduced Calcineurin Inhibitor Exposure in Renal Transplantation. J Am Soc Nephrol : JASN, 2018. 29: 1979. 248. Bloom, R.D., et al. A randomized, crossover pharmacokinetic study comparing generic tacrolimus vs. the reference formulation in subpopulations of kidney transplant patients. Clin Transplant, 2013. 27: E685. 249. Glander, P., et al. Bioavailability and costs of once-daily and twice-daily tacrolimus formulations in de novo kidney transplantation. Clin Transplant, 2018: e13311. 250 (...) . Guirado, L., et al. Medium-Term Renal Function in a Large Cohort of Stable Kidney Transplant Recipients Converted From Twice-Daily to Once-Daily Tacrolimus. Transplant Dir, 2015. 1: e24. 251. Melilli, E., et al. De novo use of a generic formulation of tacrolimus versus reference tacrolimus in kidney transplantation: Evaluation of the clinical results, histology in protocol biopsies, and immunological monitoring. Transplant Int, 2015. 28: 1283. 252. Robertsen, I., et al. Use of generic tacrolimus

2019 European Association of Urology

169. Urolithiasis

tomography of the kidneys, ureters and bladder for urolithiasis. J Med Imaging Radiat Oncol, 2017. 61: 582. 52. Poletti, P.A., et al. Low-dose versus standard-dose CT protocol in patients with clinically suspected renal colic. AJR Am J Roentgenol, 2007. 188: 927. 53. Zheng, X., et al. Dual-energy computed tomography for characterizing urinary calcified calculi and uric acid calculi: A meta-analysis. Eur J Radiol, 2016. 85: 1843. 54. Niemann, T., et al. Diagnostic performance of low-dose CT (...) . PLoS One, 2016. 11: e0158661. 149. Lopez-Acon, J.D., et al. Analysis of the Efficacy and Safety of Increasing the Energy Dose Applied Per Session by Increasing the Number of Shock Waves in Extracorporeal Lithotripsy: A Prospective and Comparative Study. J Endourol, 2017. 31: 1289. 150. Connors, B.A., et al. Effect of initial shock wave voltage on shock wave lithotripsy-induced lesion size during step-wise voltage ramping. BJU Int, 2009. 103: 104. 151. Handa, R.K., et al. Optimising an escalating

2019 European Association of Urology

171. Guidance on the clinical management of anxiety disorders, specifically focusing on diagnosis and treatment strategies

daily role for less than 1 day per month, 1–7 days per month and more than 7 days per month, respectively. This classification is based on the distribution of number of complete days out of role reported by people in the Australian National Survey of Mental Health and Wellbeing (Slade et al., 2009b) who met criteria for one or more of panic disorder, SAD or GAD. # Medication should be combined with advice about graded exposure to feared situations. †Review after 4–6 sessions of weekly CBT, or after (...) or GAD; • • Papers with level I evidence for intervention studies (i.e. meta-analyses or systematic reviews of ran- domised controlled trials [RCTs]); • • Papers published in English. Studies were excluded if the focus was not on the rele- vant disorders or if insufficient details were provided to allow synthesis. For each included study, the level of evidence was assessed according to the Australian National Health and Medical Research Council (NHMRC) classification for intervention studies (Table 1

2018 Royal Australian and New Zealand College of Psychiatrists

172. Incontinence after Prostate Treatment: AUA/SUFU Guideline (2019)

benefit from being able to assess which patient will likely experience further symptom recovery versus those who will not. This allows clinicians to set clear and reasonable expectations regarding the short-, medium-, and long-term sequela of IPT. Although most clinicians are familiar with the more commonly known term “post-prostatectomy incontinence,” this guideline uses the term IPT, which is more inclusive given that it covers the management of patients who have incontinence after undergoing RP, RT (...) . Additionally, a call for reviewers was placed on the AUA website from January 14-28, 2019 to allow any additional interested parties to request a copy of the document for review. The guideline was also sent to the Urology Care Foundation to open the document further to the patient perspective. The draft guideline document was distributed to 49 external peer reviewers. All peer review comments were blinded and sent to the Panel for review. In total, 33 reviewers (9 AUA PGC, SQC, and BOD reviewers; 22

2019 Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction

175. Assessment and Management of Patients at Risk for Suicide

. However, there was no increase in the prevalence of suicide attempts between 2016 and 2017 for this age group. SAMHSA notes that this increase in suicide-related behavior over the past 10 years co-occurs with a similar increase in the prevalence of mental health VA/DoD Clinical Practice Guideline for the Assessment and Management of Patients at Risk for Suicide May 2019 Page 8 of 142 conditions that cause significant impairment in daily life functioning, especially the occurrence of major depressive

2019 VA/DoD Clinical Practice Guidelines

176. Management of Stroke Rehabilitation

patients, poor functional outcomes are commonplace. Approximately 44% of individuals aged 18-50 experience moderate disability after stroke, requiring at least some assistance with activities of daily living (ADL) and/or mobility (modified Rankin Scale score >2).[3] Even in patients with so-called “mild” or “improving” stroke, a recent study found that only 28% were discharged to home, 16% required admission to acute rehabilitation facilities, and 11% were admitted to skilled nursing facilities.[4] VA (...) and independence. Abbreviations: ADLs: activities of daily living; DoD: Department of Defense; VA: Department of Veterans Affairs C. Conflicts of Interest At the start of this guideline development process and at other key points throughout, the project team was required to submit disclosure statements to reveal any areas of potential conflict of interest (COI) in the past 24 months. Verbal affirmations of no COI were used as necessary during meetings throughout the guideline development process. The project

2019 VA/DoD Clinical Practice Guidelines

177. The economic evaluation of early intervention with Anti-Tumor Necrosis Factor-alpha treatments in pediatric Crohn's disease

state only needed to be carried over once. Whether a subject was refractory within the first three months of treatment could not be determined because this state was not captured for the majority of subjects. 37 Table 2.2.2.2.1-1. The Weighted PCDAI Scoring System. Parameter Parameter Description Parameter Score Abdominal pain None (no pain) 0 Mild, brief, does not interfere with activity 10 Moderate-to-severe, daily pain, longer lasting, affects activity, nocturnal 20 Patient functioning/ general

2019 SickKids Reports

179. Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD

about the effectiveness and harms of pharmacologic and nonpharmacologic treatments for exacerbations of chronic obstructive pulmonary disease (ECOPD). Data sources. Embase ® , Epub Ahead of Print, In-Process & Other Non-Indexed Citations, MEDLINE ® Daily, MEDLINE, Cochrane Central Registrar of Controlled Trials, Ovid Cochrane Database of Systematic Reviews, and Scopus from database inception to January 2, 2019. Review methods. We included randomized controlled trials (RCTs) that evaluated (...) , routes of administration, and duration of treatment) of antibiotics and corticosteroids. The majority of studies were conducted in hospitalized patients with moderate or severe ECOPD with only a small number of studies conducted in outpatients with mild or mild to moderate ECOPD. Lung function was the most frequently assessed outcome, and often studies did not measure final health outcomes, such as mortality, resolution of exacerbation, hospital readmission etc., to allow for assessment

2019 Effective Health Care Program (AHRQ)

180. Integrated care for older people (?ICOPE)?: guidance for person-centred assessment and pathways in primary care

its contents and by organizing the experts’ meetings. We also benefited from the inputs of participants at the annual meeting of WHO Clinical Consortium on Healthy Ageing, December 2018. The WHO Department Ageing and Life Course acknowledges the financial support of the Government of Japan, the Government of Germany and the Kanagawa Prefectural Government in Japan. Editing by Green Ink. ivABBREVIATIONS ADLs activities of daily living BMI body mass index CBT cognitive behavioural therapy ICOPE (...) , integrated approach also embraces the context of individuals’ daily lives, including the impact of their health and needs on those close to them and in their communities. There are ?ve steps to meeting older people’s health and social care needs with an integrated care approach, as shown in the following general pathway. ASSESSING OLDER PEOPLE’S NEEDS AND DEVELOPING A PERSONALIZED CARE PLAN KEY POINTS • The identi?cation of older people in the communi- ty with priority conditions associated with declines

2019 World Health Organisation Guidelines

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