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DOT Examination

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81. White Dot Syndromes (Follow-up)

. Multiple evanescent white dot syndrome in right eye. Diagnosis Fluorescein angiography demonstrates early punctate hyperfluorescence with late staining, in areas corresponding to the white dots, as shown in the image below. Fluorescein angiogram of multiple evanescent white dot syndrome in right eye. This angiogram demonstrates hyperfluorescence corresponding to white spots, mild macular edema, and disc leakage. On closer examination, the early fluorescence of the lesions appears in a wreathlike (...) White Dot Syndromes (Follow-up) White Dot Syndromes: Overview, Acute Posterior Multifocal Placoid Pigment Epitheliopathy, Serpiginous Choroiditis Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache

2014 eMedicine.com

82. ATYPICAL PRESENTATIONS OF MULTIPLE EVANESCENT WHITE DOT SYNDROME WITHOUT WHITE DOTS: A Case Series. (PubMed)

ATYPICAL PRESENTATIONS OF MULTIPLE EVANESCENT WHITE DOT SYNDROME WITHOUT WHITE DOTS: A Case Series. To describe three unusual clinical cases of patients who were diagnosed with multiple evanescent white dot syndrome at the onset of their disease but lacked the characteristic white dots on clinical examination, autofluorescence, and angiographic testing at any time during their follow-up.Three eyes of three patients with clinical symptoms of multiple evanescent white dot syndrome seen (...) at an academic clinical practice were included. Retinal imaging, including fluorescein angiography, indocyanine green imaging, fundus autofluorescence, and optical coherence tomography, was used to further characterize and describe the clinical findings.All three patients presented with classic multiple evanescent white dot syndrome complaints. All patients demonstrated classic foveal granularity and mild disk swelling and/or peripapillary whitening. No characteristic hyperfluorescent lesions were seen

2011 Retina

83. Photoluminescence of a microcavity quantum dot system in the quantum strong-coupling regime (PubMed)

than one are excited. This regime has been recently achieved in semiconductor nanostructures, where a quantum dot is trapped in a planar microcavity. Here we study the quantum strong-coupling regime by calculating its photoluminescence (PL) properties under a pulsed excitation. We discuss the changes in the PL as the QSC regime is reached, which transitions between a peak around the cavity resonance to a doublet. We particularly examine the variations of the PL in the time domain, under regimes (...) Photoluminescence of a microcavity quantum dot system in the quantum strong-coupling regime The Jaynes-Cummings model, describing the interaction between a single two-level system and a photonic mode, has been used to describe a large variety of systems, ranging from cavity quantum electrodynamics, trapped ions, to superconducting qubits coupled to resonators. Recently there has been renewed interest in studying the quantum strong-coupling (QSC) regime, where states with photon number greater

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2013 Scientific reports

84. Photodeposition of Ag2S on TiO2 nanorod arrays for quantum dot-sensitized solar cells (PubMed)

deposited electrodes show a broad absorption range of the visible light. The quantum dot-sensitized solar cells (QDSSCs) based on these electrodes were fabricated, and the photoelectrochemical properties were examined. A high photocurrent density of 10.25 mA/cm2 with a conversion efficiency of 0.98% at AM 1.5 solar light of 100 mW/cm2 was obtained with an optimal photodeposition time. The performance of the QDSSC at different incident light intensities was also investigated. The results display a better (...) Photodeposition of Ag2S on TiO2 nanorod arrays for quantum dot-sensitized solar cells Ag2S quantum dots were deposited on the surface of TiO2 nanorod arrays by a two-step photodeposition. The prepared TiO2 nanorod arrays as well as the Ag2S deposited electrodes were characterized by X-ray diffraction, scanning electron microscope, and transmission electron microscope, suggesting a large coverage of Ag2S quantum dots on the ordered TiO2 nanorod arrays. UV-vis absorption spectra of Ag2S

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2013 Nanoscale research letters

85. Prior eccentric exercise reduces v[combining dot above]o2peak and ventilatory threshold but does not alter movement economy during cycling exercise. (PubMed)

was to examine the impact of EIMD targeted specifically to the quadriceps muscle group on peak oxygen consumption (V[Combining Dot Above]O2peak) during cycling. Ten participants (4 men, 6 women) completed a V[Combining Dot Above]O2peak test on a cycle ergometer before and 48 hours after performing 24 eccentric contractions with their right and left quadriceps with a weight equal to 120% of 1-repetition maximal concentric strength (1RM). The EIMD was assessed using 1RM, and muscle soreness was assessed using (...) Prior eccentric exercise reduces v[combining dot above]o2peak and ventilatory threshold but does not alter movement economy during cycling exercise. Exercise-induced muscle damage (EIMD) has been shown to reduce force production and result in delayed-onset soreness and pain in the damaged muscle(s). Cycling in the presence of EIMD reduces peak power output and time-trial performance. However, its effect on peak aerobic capacity has not been widely studied. The purpose of this study

2012 Journal of strength and conditioning research / National Strength & Conditioning Association

86. Serodiagnosis of bovine fasciolosis by Dot-enzyme immuno assay in Chennai, Tamil Nadu (PubMed)

Serodiagnosis of bovine fasciolosis by Dot-enzyme immuno assay in Chennai, Tamil Nadu Excretory/secretory (E/S) antigen of adult Fasciola gigantica was used for diagnosis of fasciolosis in cattle and buffaloes sera from slaughter houses and different places in and around Chennai, Tamil Nadu. A total of 6.4 mg of E/S antigen was obtained from the 60 flukes collected from slaughter houses. Coprological examination was done to detect endoparasitic infection in 321 fecal samples. Dot-enzyme immuno (...) and 92.10 %, respectively in comparison to fecal examination by sedimentation method. Dot-EIA can be easily adapted in the field to detect fasciolosis in cattle and buffaloes.

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2012 Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology

87. Toxicity of quantum dots and cadmium salt to Caenorhabditis elegans after multigenerational exposure (PubMed)

Toxicity of quantum dots and cadmium salt to Caenorhabditis elegans after multigenerational exposure To fully understand the biological and environmental impacts of nanomaterials requires studies that address both sublethal end points and multigenerational effects. Here, we use a nematode to examine these issues as they relate to exposure to two different types of quantum dots, core (CdSe) and core-shell (CdSe/ZnS), and to compare the effect to those observed after cadmium salt exposures (...) . The strong fluorescence of the core-shell QDs allowed for the direct visualization of the materials in the digestive track within a few hours of exposure. Multiple end points, including both developmental and locomotive, were examined at QD exposures of low (10 mg/L Cd), medium (50 mg/L Cd), and high concentrations (100 mg/L Cd). While the core-shell QDs showed no effect on fitness (lifespan, fertility, growth, and three parameters of motility behavior), the core QDs caused acute effects similar to those

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2012 Environmental science & technology

88. Intravitreal Silicon-based Quantum dots as neuroprotective factors in a model of retinal photoreceptor degeneration. (PubMed)

Intravitreal Silicon-based Quantum dots as neuroprotective factors in a model of retinal photoreceptor degeneration. To study the intravitreal application of silicon quantum dots (QDs) and their capabilities to deliver electrical stimulation to the retinal cells and to assess the potential effect on retinal electrophysiology and anatomy.A Royal College of Surgeon rat model of retinal degeneration was used in this study. A total of 32 eyes were used, divided in four groups of 8 eyes each (...) response compared with the sham and control groups (P < 0.05). The pathologic examination demonstrated a higher nuclei count in the QD group, consistent with a higher cell survival rate than that in the sham and control groups in which cells degenerated as expected.Intravitreal injection of silicon-based QD seems to be safe and well tolerated, with no evident toxic reaction and demonstrates a beneficial effect by prolonging cell survival rate and improving ERG patterns in a well-established model

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2012 Investigative Ophthalmology & Visual Science

89. A Highly Sensitive Method for Molecular Diagnosis of Fungal Keratitis: A Dot Hybridization Assay. (PubMed)

negative results by culture, and 10 of the 11 samples were considered to be positive for FK by cloning and resequencing of the amplified ITS fragment and by a pathologic examination or clinical course review. The sensitivities for diagnosis of FK by the dot hybridization assay and culture were 100% and 50%, respectively, whereas the specificities were 96.7% and 100%, respectively.The dot hybridization assay is a highly sensitive and specific diagnostic tool for FK. The method provides a much higher (...) A Highly Sensitive Method for Molecular Diagnosis of Fungal Keratitis: A Dot Hybridization Assay. Fungal keratitis (FK) is an important cause of ocular morbidity, especially for people living in the agricultural communities of the developing world. Current diagnostic methods may lack sensitivity (direct microscopy) or are time consuming (culture). The aim of this study was to develop a dot hybridization assay for sensitive and rapid diagnosis of FK.Evaluation of diagnostic test

2012 Ophthalmology

90. 'Black dots' seen under trichoscopy are not specific for alopecia areata. (PubMed)

(TE), 23 with other hair and scalp diseases] and 93 healthy controls were examined, using a videodermoscope with 20-70 times magnification.There was a correlation between the black dots and the early acute phase of the various alopecia types with the presence of the black dots. Black dots were found in 11% (22/107) of patients with hair loss, including 53.3% (16/30) with AA; in 40% (2/5) of patients with severe chemotherapy-induced alopecia, and in 100% of patients with dissecting cellulitis (...) 'Black dots' seen under trichoscopy are not specific for alopecia areata. 'Black dots' are macrocomedo-like round structures localized to the follicular ostium, and are considered a specific trichoscopic feature of alopecia areata (AA).To characterize specific features of 'black dots', and assess their possible presence in common hair and scalp disorders.In total, 107 patients with hair loss [30 with alopecia areata (AA), 37 with androgenetic alopecia (AGA), 17 with chronic telogen effluvium

2012 Clinical & Experimental Dermatology

91. Identifying selective visual attention biases related to fear of pain by tracking eye movements within a dot-probe paradigm. (PubMed)

Identifying selective visual attention biases related to fear of pain by tracking eye movements within a dot-probe paradigm. This research examined selective biases in visual attention related to fear of pain by tracking eye movements (EM) toward pain-related stimuli among the pain-fearful. EM of 21 young adults scoring high on a fear of pain measure (H-FOP) and 20 lower-scoring (L-FOP) control participants were measured during a dot-probe task that featured sensory pain-neutral, health (...) times to dot probes. Finally, both groups showed a cycle of disengagement followed by re-engagement toward sensory pain words relative to other word types. In sum, this research is the first to reveal biases toward pain stimuli during very early stages of visual information processing among the highly pain-fearful and highlights the utility of EM tracking as a means to evaluate visual attention as a dynamic process in the context of FOP.Copyright © 2012 International Association for the Study

2012 Pain

92. Quantum Dot Immunocytochemical Localization of Somatostatin in Somatostatinoma by Widefield Epifluorescence, Super-resolution Light, and Immunoelectron Microscopy (PubMed)

Quantum Dot Immunocytochemical Localization of Somatostatin in Somatostatinoma by Widefield Epifluorescence, Super-resolution Light, and Immunoelectron Microscopy Quantum dot nanocrystal probes (QDs) have been used for detection of somatostatin hormone in secretory granules of somatostatinoma tumor cells by immunofluorescence light microscopy, super-resolution light microscopy, and immunoelectron microscopy. Immunostaining for all modalities was done using sections taken from an epoxy resin (...) -embedded tissue specimen and a similar labeling protocol. This approach allowed assessment of labeling at light microscopy level before examination at super-resolution and electron microscopy level and was a significant aid in interpretation. Etching of ultrathin sections with saturated sodium metaperiodate was a critical step presumably able to retrieve some tissue antigenicity masked by processing in epoxy resin. Immunofluorescence microscopy of QD-immunolabeled sections showed somatostatin hormone

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2012 Journal of Histochemistry and Cytochemistry

93. Multiple evanescent white dot syndromes (PubMed)

Multiple evanescent white dot syndromes The aim of this study is to report a patient with multipe evanescent white dot syndrome (MEWDS) presenting with classic foveal granularity and pathology localized to the outer retina.Case study methodology was used in the current study.A 34-year-old Caucasian female presented with photopsias and blurry vision in her left eye. Examination, particularly the foveal granularity noted in her affected eye, was archetypal for the diagnosis of MEWDS. Fundus

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2011 Journal of ophthalmic inflammation and infection

94. Inhibition of Angiogenesis by HC{middle dot}HA, a Complex of Hyaluronan and the Heavy Chain of Inter-{alpha}-Inhibitor, Purified from Human Amniotic Membrane. (PubMed)

Inhibition of Angiogenesis by HC{middle dot}HA, a Complex of Hyaluronan and the Heavy Chain of Inter-{alpha}-Inhibitor, Purified from Human Amniotic Membrane. To determine whether antiangiogenic action of the amniotic membrane (AM) can be mediated by HC·HA, a covalent complex of hyaluronan (HA) and the heavy chain (HC) of inter-α-inhibitor, purified from AM soluble extract.HC·HA action on viability, proliferation, attachment, death, migration, and differentiation of human umbilical vein (...) endothelial cells (HUVECs) and neovascularization in chicken chorioallantoic membrane (CAM) was examined by MTT assay, BrdU labeling, cell proliferation assay, cell death detection ELISA, transwell assay, tube formation assay, and CAM assay.HC·HA suppressed HUVEC viability more significantly than HA and AM stromal extract, and such suppression was not mediated by CD44. HC·HA also caused HUVECs to become small and rounded, with a decrease in spreading and filamentous actin. Without promoting cell

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2011 Investigative Ophthalmology & Visual Science

95. Reflectance confocal microscopy of the yellow dot pattern in alopecia areata. (PubMed)

by RCM examination of the same area. After RCM, a 5-mm punch biopsy specimen was also taken. Dermoscopic findings showed the yellow dot pattern in all patients, with round or polycyclic yellow-pink dots often containing miniaturized or broken hair shafts. At RCM, a Vivablock mosaic taken at the level of the spinous layer showed striking reduction of follicular adnexal structures and empty lumina containing highly refractile material corresponding to the yellow dots seen on dermoscopy (...) Reflectance confocal microscopy of the yellow dot pattern in alopecia areata. The presence of yellow dots is a characteristic dermoscopic finding in alopecia areata. The aim of this study was to investigate the yellow dot pattern observed at dermoscopy in alopecia areata with reflectance confocal microscopy (RCM) and correlate RCM findings with pathological features.Six patients affected by alopecia totalis entered the study. Patients were first submitted to scalp dermoscopy, which was followed

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2011 Archives of Dermatology

96. Diffuse Optical Tomography (DOT) for Monitoring Response to Neoadjuvant (Preoperative) Chemotherapy in Breast Cancer

to ten patients over one year. Patients receiving neoadjuvant chemotherapy for breast cancer will undergo baseline clinical examination, mammography, ultrasound, MRI and DOT before commencement of treatment. DOT will be repeated at 1,3,6 weeks after chemotherapy, and at the end of each chemotherapy regimen. Ultrasound will be repeated every 6 weeks and at the end of treatment. Mammography and MRI will be repeated once at the end of treatment before surgery. A breast pathologist will evaluate (...) with histopathological response. Secondary Outcome Measures : Change in DOT parameters such as BVI, SO2, blood perfusion dynamic fluctuation [ Time Frame: These parameters will be obtained from patients during neoadjuvant chemotherapy process, which is up to an average of 6 months ] The change in DOT parameters such as BVI, SO2, blood perfusion dynamic fluctuation will be correlated with response based on clinical examination, ultrasound, MMG and MRI. Standard definitions for clinical response will be used

2011 Clinical Trials

97. Neuro-ophthalmic Examination (Overview)

shakes hands with the patient, observe the patient's fingers, skin, and grip. Mental status, speech, and affect can be assessed during history taking. Sensory testing Stereovision testing and Worth 4-dot testing are not routine parts of the neuro-ophthalmic examination, but they are useful in certain situations. Sensory testing is best performed before fusion is disrupted by ocular occlusion. The author's preferred stereovision test is the Titmus stereofly test. Stereovision testing is used commonly (...) in pediatric ophthalmologic examinations, and it is useful in patients with suspected functional visual loss. A normal result on stereovision testing suggests 20/20 acuity in both eyes and is not compatible with poor visual acuity. Worth 4-dot testing is useful if patients have difficulty expressing their diplopia. In patients with strabismus and good acuity in both eyes, central suppression suggests an element of amblyopia rather than an acquired motility deficit. The green filter should be placed before

2014 eMedicine.com

98. Approach to the Genitourinary Patient - Physical Examination

(eg, due to rhabdomyolysis) causes a positive result. Hemoglobinuria and myoglobinuria can be distinguished from hematuria by the absence of RBCs on microscopic examination and by the pattern of color change on the test strip. RBCs create a dotted or speckled pattern; free Hb and myoglobin create a uniform color change. Povidone iodine causes false-positive results (uniform coloring); ascorbic acid causes false-negative results. Nitrites are produced when bacteria reduce urinary nitrates derived (...) Approach to the Genitourinary Patient - Physical Examination Evaluation of the Renal Patient - Genitourinary Disorders - MSD Manual Professional Edition Brought to you by The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases / / / / IN THIS TOPIC OTHER TOPICS

2013 Merck Manual (19th Edition)

99. Idiopathic Choroidal Neovascularisation as the Inaugural Sign of Multiple Evanescent White Dot Syndrome (PubMed)

Idiopathic Choroidal Neovascularisation as the Inaugural Sign of Multiple Evanescent White Dot Syndrome We report a case of multiple evanescent white dot syndrome (MEWDS) that presented with putative idiopathic choroidal neovascularisation (ICNV) before showing angiographic signs typical of MEWDS. A 16-year-old male presented with unilateral metamorphopsias and visual loss in his left eye. ICNV with subretinal hemorrhage was diagnosed and treated with intravitreal Avastin(®). Fifteen days later (...) , regression of choriodal neovascularization (CNV) was documented together with the appearance of fluorescein angiography (FA) and indocyanine green angiography (ICGA) signs typical for MEWDS, that included faint mottled FA hyperfluorescence in the mid-peripheral fundus, irregularly shaped mid-peripheral ICGA dark areas in the intermediate angiographic phase that were clearly delineated in the late phase as well as peripapillary hypofluorescence. Fundus examination appeared completely normal during

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2010 Middle East African journal of ophthalmology

100. Directly-observed therapy (DOT) for the radical 14-day primaquine treatment of Plasmodium vivax malaria on the Thai-Myanmar border. (PubMed)

Directly-observed therapy (DOT) for the radical 14-day primaquine treatment of Plasmodium vivax malaria on the Thai-Myanmar border. Plasmodium vivax has a dormant hepatic stage, called the hypnozoite, which can cause relapse months after the initial attack. For 50 years, primaquine has been used as a hypnozoitocide to radically cure P. vivax infection, but major concerns remain regarding the side-effects of the drug and adherence to the 14-day regimen. This study examined the effectiveness (...) of using the directly-observed therapy (DOT) method for the radical treatment of P. vivax malaria infection, to prevent reappearance of the parasite within the 90-day follow-up period. Other potential risk factors for the reappearance of P. vivax were also explored.A randomized trial was conducted from May 2007 to January 2009 in a low malaria transmission area along the Thai-Myanmar border. Patients aged ≥ 3 years diagnosed with P. vivax by microscopy, were recruited. All patients were treated

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2010 Malaria journal

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