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61. Examining the Roles of Emulsion Droplet Size and Surfactant in the Interfacial Instability-Based Fabrication Process of Micellar Nanocrystals (PubMed)

Examining the Roles of Emulsion Droplet Size and Surfactant in the Interfacial Instability-Based Fabrication Process of Micellar Nanocrystals The interfacial instability process is an emerging general method to fabricate nanocrystal-encapsulated micelles (also called micellar nanocrystals) for biological detection, imaging, and therapy. The present work utilized fluorescent semiconductor nanocrystals (quantum dots or QDs) as the model nanocrystals to investigate the interfacial instability

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2017 Nanoscale research letters

62. Distribution Characteristics of Human Papillomavirus Infection: A Study Based on Data from Physical Examination (PubMed)

Distribution Characteristics of Human Papillomavirus Infection: A Study Based on Data from Physical Examination Objective: Human papillomavirus (HPV) is the primary cause of cervical cancer. The purpose of this study was to investigate the prevalence and type distribution of HPV DNA positive in women undergoing routine physical examination. Methods: 2,452 women were enrolled between March and November 2013. Participants were tested for 23 HPV types using polymerase chain reaction (PCR (...) ) and reverse dot blot hybridization. HPV DNA detection prevalence was estimated in different age groups. Results: Mean age (SD) of study participants was 47.7 (9.8) years. Overall HPV-positive prevalence was 18.9% (463/2452), and 22 out of 23 known subtypes were detected. Single HPV subtype prevalence of infection was 14.4%, and multiple prevalence of infection was 4.5%. The prevalence of HPV DNA in different age groups (20-29, 30-39, 40-49, 50-59, 60-69, ≥70) were 9.3%, 15.6%, 17.1%, 22.1%, 23.0% and 20.0

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2017 Asian Pacific journal of cancer prevention : APJCP

63. Prevalence of Resistant Hypertension With DOT

Prevalence of Resistant Hypertension With DOT Prevalence of Resistant Hypertension With DOT - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Prevalence of Resistant Hypertension With DOT (DOT) The safety (...) who are non-adherent based on direct observed therapy, and follow them up to examine the impact of this diagnosis. Condition or disease Intervention/treatment Hypertension Procedure: Direct Observed Therapy test Detailed Description: This is a prospective, observational study. Patients fitting inclusion and exclusion criteria, after informed consent, will undergo the direct observed therapy test in the hypertension unit (this is usual care in the unit, which they will undergo even

2015 Clinical Trials

64. Connecting the Dots: Linking the National Program of Cancer Registries and the Needs of Survivors and Clinicians. (PubMed)

Connecting the Dots: Linking the National Program of Cancer Registries and the Needs of Survivors and Clinicians. Cancer survivors, the medical community, public health professionals, researchers, and policymakers all need information about newly diagnosed cancer cases and deaths to better understand and address the disease burden. CDC collects cancer data on 96% of the U.S. population through the National Program of Cancer Registries. The National Program of Cancer Registries routinely (...) collects data on all cancer occurrences, deaths, and the types of initial treatment received by the patients, and recently CDC has made advances in its cancer surveillance activities that have direct applicability to cancer survivorship research and care. This article examines CDC's innovative uses of the National Program of Cancer Registries infrastructure and data as a recruitment source for survivorship research studies and behavioral interventions; comparative effectiveness and patient-centered

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2015 American journal of preventive medicine

65. Mitochondrial Toxicity of Cadmium Telluride Quantum Dot Nanoparticles in Mammalian Hepatocytes (PubMed)

Mitochondrial Toxicity of Cadmium Telluride Quantum Dot Nanoparticles in Mammalian Hepatocytes There are an increasing number of studies indicating that mitochondria are relevant targets in nanomaterial-induced toxicity. However, the underlying mechanisms by which nanoparticles (NPs) interact with these organelles and affect their functions are unknown. The aim of this study was to investigate the effects of cadmium telluride quantum dot (CdTe-QD) NPs on mitochondria in human hepatocellular (...) carcinoma HepG2 cells. CdTe-QD treatment resulted in the enlargement of mitochondria as examined with transmission electron microscopy and confocal microscopy. CdTe-QDs appeared to associate with the isolated mitochondria as detected by their inherent fluorescence. Further analyses revealed that CdTe-QD caused disruption of mitochondrial membrane potential, increased intracellular calcium levels, impaired cellular respiration, and decreased adenosine triphosphate synthesis. The effects of CdTe-QDs

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2015 Toxicological Sciences

66. Patients’ Experience of Tuberculosis Treatment Using Directly Observed Treatment, Short-Course (DOTS): A Qualitative Study (PubMed)

' experience of tuberculosis treatment according to DOTS in Iran.This study is a qualitative study, using content analysis to examine patients' experience of TB treatment and to understand their compliance during DOTS. In this study, a semi-structured interview with open questions was answered by 40 patients, who had a diagnosis of pulmonary and extrapulmonary tuberculosis, and improved during the course of their treatment. The method of sampling was purposive sample and the interview process lasted until (...) Patients’ Experience of Tuberculosis Treatment Using Directly Observed Treatment, Short-Course (DOTS): A Qualitative Study Despite effective diagnosis and treatment, prevalence of tuberculosis (TB) is still growing. The directly observed treatment, short-course (DOTS) strategy to treat TB was introduced by the World Health Organization more than a decade ago. Little is known about patients' experience of TB treatment, according to DOTS, in Iran.This study aimed to understand the patients

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2015 Iranian Red Crescent medical journal

67. Trichoscopy findings in loose anagen hair syndrome: rectangular granular structures and solitary yellow dots (PubMed)

Trichoscopy findings in loose anagen hair syndrome: rectangular granular structures and solitary yellow dots Loose anagen hair syndrome (LAHS) is typically diagnosed in girls older than 2 years who present with hair that "will not grow". Hair microscopic examination shows absent inner and outer root sheaths, ruffling of the cuticle on the proximal hair shaft and deformed pigmented anagen bulbs.The aim of the study was to assess whether there are characteristic trichoscopic features favoring (...) the diagnosis of LAHS.Eighty nine children patients were included into the study (24 girls with LAHS, 25 with alopecia areata, 20 with telogen effluvium and 20 healthy children). In all groups trichoscopy was performed. Trichoscopy images were analyzed for abnormalities in the hairs shafts, the hair follicle openings and the interfollicular area.Dirty dots were present in all groups. A unique feature of LAHS was the presence of rectangular black granular structures which differs from dense black dots seen

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2015 Journal of dermatological case reports

68. Optical characterization of In-flushed InAs/GaAs quantum dots emitting a broadband spectrum with multiple peaks at ~1 μm (PubMed)

Optical characterization of In-flushed InAs/GaAs quantum dots emitting a broadband spectrum with multiple peaks at ~1 μm We investigated optical properties of In-flushed InAs quantum dots (QDs) grown on a GaAs substrate by molecular beam epitaxy. By using the In-flush technique for setting the height of self-assembled InAs QDs, we have tuned the emission wavelength of InAs QDs to the ~1 μm regime, which can be utilized as a non-invasive and deeply penetrative probe for biological and medical (...) imaging systems. The controlled emission exhibited a broadband spectrum comprising multiple peaks with an interval of approximately 30 meV. We examined the origin of the multiple peaks using spectral and time-resolved photoluminescence, and concluded that it is attributed to monolayer step fluctuations in the height of the In-flushed QDs. This feature can be advantageous for realizing a broadband light source centered at the ~1 μm regime, which is especially suitable for the non-invasive cross

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2015 Nanoscale research letters

69. Associations between childhood maltreatment and emotion processing biases in major depression: results from a dot-probe task. (PubMed)

major depression are associated with experienced childhood neglect or abuse remains unclear.A sample of 45 patients suffering from major depression were recruited to examine correlations between maltreatment experienced during childhood and attentional biases to sad and happy facial expressions. Attention allocation was assessed using the dot-probe task and a history of childhood maltreatment was measured by means of the 25-item Childhood Trauma Questionnaire (CTQ).Our results indicate (...) Associations between childhood maltreatment and emotion processing biases in major depression: results from a dot-probe task. Childhood maltreatment is considered an important risk factor for the development of major depression. Research indicates an association between childhood adversity and altered emotion processing. Depression is characterized by mood-congruent cognitive biases, which play a crucial role in symptom persistence and recurrence. However, whether attentional biases in adult

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2015 BMC Psychiatry

70. Applying Fluorescence Resonance Energy Transfer (FRET) to Examine Effector Translocation Efficiency by Coxiella burnetii during siRNA Silencing (PubMed)

Applying Fluorescence Resonance Energy Transfer (FRET) to Examine Effector Translocation Efficiency by Coxiella burnetii during siRNA Silencing Coxiella burnetii, the causative agent of Q fever, is an intracellular pathogen that relies on a Type IV Dot/Icm Secretion System to establish a replicative niche. A cohort of effectors are translocated through this system into the host cell to manipulate host processes and allow the establishment of a unique lysosome-derived vacuole for replication (...) . The method presented here involves the combination of two well-established techniques: specific gene silencing using siRNA and measurement of effector translocation using a FRET-based substrate that relies on β-lactamase activity. Applying these two approaches, we can begin to understand the role of host factors in bacterial secretion system function and effector translocation. In this study we examined the role of Rab5A and Rab7A, both important regulators of the endocytic trafficking pathway. We

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2016 Journal of visualized experiments : JoVE

71. Examining the standard model of signal detection theory in motion discrimination. (PubMed)

Examining the standard model of signal detection theory in motion discrimination. We studied a fundamental assumption in signal detection theory that is applied to motion discrimination. Using random-dot motion stimuli of 100% coherence, it is natural to represent the two directions as two normal distributions. Then a same-different task and a forced-choice task should give rise to consistent d' estimates, because both tasks share the same underlying signal detection theory model. To verify

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2016 Journal of vision

72. A Study Examining Adolescents With Non-Suicidal Self-Injury

A Study Examining Adolescents With Non-Suicidal Self-Injury A Study Examining Adolescents With Non-Suicidal Self-Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study Examining Adolescents With Non (...) - Clinical and Translational Science Institute Collaborator: National Institute of Mental Health (NIMH) Information provided by (Responsible Party): University of Minnesota - Clinical and Translational Science Institute Study Details Study Description Go to Brief Summary: This study will examine longitudinal brain development in young adolescent girls with a history of Non-Suicidal Self-Injury (NSSI). Specifically, three constructs outlined by the the Research Domains Criteria (RDoC) will be examined

2016 Clinical Trials

73. CT Findings of Axillary Tuberculosis Lymphadenitis: A Case Detected by Breast Cancer Screening Examination (PubMed)

CT Findings of Axillary Tuberculosis Lymphadenitis: A Case Detected by Breast Cancer Screening Examination We report the first description of CT findings of axillary tuberculous lymphadenitis confirmed by the pathological specimen. The breast cancer screening examination is one of the prime methods of detection of axillary tuberculous lymphadenitis. The most common site of axillary tuberculous lymphadenitis is the deep axilla. Screening mammography often fails to cover the whole axilla (...) . The presence on the contrast-enhanced CT of unilateral multiple circumscribed dense nodes, some of which have large and dotted calcifications, might suggest tuberculous lymphadenitis in axillary region.

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2016 Case Reports in Radiology

74. The role of retinopathy distribution and other lesion types for the definition of examination intervals during screening for diabetic retinopathy. (PubMed)

to assess whether the features could predict the discrepancy between the grader and the risk model.Suspicion of tumours, retinal degeneration and vascular diseases other than diabetic retinopathy could explain why the clinician recommended shorter examination intervals than the model. Additionally, the regional distribution of microaneurysms/dot haemorrhages was important for defining a photograph as belonging to the group where both the clinician and the risk model had recommended a short screening (...) The role of retinopathy distribution and other lesion types for the definition of examination intervals during screening for diabetic retinopathy. It has previously been shown that the intervals between screening examinations for diabetic retinopathy can be optimized by including individual risk factors for the development of the disease in the risk assessment. However, in some cases, the risk model calculating the screening interval may recommend a different interval than an experienced

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2016 Acta ophthalmologica

75. Incipient white dot fovea syndrome in a child. (PubMed)

Incipient white dot fovea syndrome in a child. An 8-year-old girl with normal visual acuity was found to have bilateral macular lesions on retinal examination. Ocular coherence tomography showed discrete perifoveal inner retinal deposits that characterize the "white dot fovea." This report documents the clinical presentation of white dot fovea in early childhood, suggesting that this condition may represent an isolated foveal dystrophy. Copyright © 2014 American Association for Pediatric

2014 JAAPOS - Journal of the American Association for Pediatric Ophthalmology and Strabismus

76. Diet and diabetes: lines and dots. (PubMed)

effects of daily walnut ingestion in diabetes and insulin resistance are profiled as an illustration, and an ongoing study examining the implications of daily walnut ingestion on diet quality and various biometric variables is described. The line between dietary pattern and the epidemiology of diabetes is indelibly established; we must work to connect the dots between here and there. (...) Diet and diabetes: lines and dots. Diabetes, particularly type 2 diabetes, is epidemic in the United States among adults and children alike, and increasingly prevalent around the world. On its current trajectory, the increasing incidence of diabetes has the potential to ravage both public health and economies. There has, however, been evidence for decades that lifestyle has enormous potential to prevent chronic disease, diabetes included. Studies suggest that the combination of tobacco

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2014 Journal of Nutrition

77. Designing and evaluation of Dot-ELISA for diagnosis of Fasciola infection in cattle (PubMed)

of slaughtered cattle were taken and examined for Fasciola infection. Sera from two groups of cattle, one infected with Fasciola (n = 60) and the other non-infected with Fasciola (n = 60), were used in the Dot- ELISA test. All sera were tested and evaluated. Except specificity, other parameters such as, sensitivity, accuracy, positive and negative predictive values of Dot- ELISA with ES Ag were better than those of Dot- ELISA with Cr Ag. In conclusion, excretory-secretory antigen dependent Dot-ELISA can (...) Designing and evaluation of Dot-ELISA for diagnosis of Fasciola infection in cattle Fasciolosis is a disease caused by liver fluck of the genus of Fasciola. Diagnosis of fasciolosis has been challenging for a long period due to low sensitivity of the coprological diagnostic method. In this study, an in-house Dot-ELISA method; using excretion-secretory (ES Ag) and Crude (Cr Ag) antigens of Fasciola was described for diagnosis of fasciolosis in cattle. For this purpose, the sera specimens

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2014 Veterinary Research Forum : an International Quarterly Journal

78. White Dot Syndromes (Overview)

. Multiple evanescent white dot syndrome in right eye. Diagnosis Fluorescein angiography demonstrates early punctate hyperfluorescence with late staining, in areas corresponding to the white dots, as shown in the image below. Fluorescein angiogram of multiple evanescent white dot syndrome in right eye. This angiogram demonstrates hyperfluorescence corresponding to white spots, mild macular edema, and disc leakage. On closer examination, the early fluorescence of the lesions appears in a wreathlike (...) White Dot Syndromes (Overview) White Dot Syndromes: Overview, Acute Posterior Multifocal Placoid Pigment Epitheliopathy, Serpiginous Choroiditis Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache

2014 eMedicine.com

79. White Dot Syndromes (Diagnosis)

. Multiple evanescent white dot syndrome in right eye. Diagnosis Fluorescein angiography demonstrates early punctate hyperfluorescence with late staining, in areas corresponding to the white dots, as shown in the image below. Fluorescein angiogram of multiple evanescent white dot syndrome in right eye. This angiogram demonstrates hyperfluorescence corresponding to white spots, mild macular edema, and disc leakage. On closer examination, the early fluorescence of the lesions appears in a wreathlike (...) White Dot Syndromes (Diagnosis) White Dot Syndromes: Overview, Acute Posterior Multifocal Placoid Pigment Epitheliopathy, Serpiginous Choroiditis Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache

2014 eMedicine.com

80. White Dot Syndromes (Treatment)

. Multiple evanescent white dot syndrome in right eye. Diagnosis Fluorescein angiography demonstrates early punctate hyperfluorescence with late staining, in areas corresponding to the white dots, as shown in the image below. Fluorescein angiogram of multiple evanescent white dot syndrome in right eye. This angiogram demonstrates hyperfluorescence corresponding to white spots, mild macular edema, and disc leakage. On closer examination, the early fluorescence of the lesions appears in a wreathlike (...) White Dot Syndromes (Treatment) White Dot Syndromes: Overview, Acute Posterior Multifocal Placoid Pigment Epitheliopathy, Serpiginous Choroiditis Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache

2014 eMedicine.com

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