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181. Cardiovascular Health in Turner Syndrome: A Scientific Statement From the American Heart Association

patient should prompt genetic evaluation for TS. All newly diagnosed individuals with TS should be evaluated by a cardiologist familiar with all aspects of cardiovascular disease seen in TS and undergo the following evaluation: – A comprehensive physical examination, including cardiac auscultation and assessment of femoral pulses and 4-extremity blood pressures (BPs), should be performed. – A complete TTE, even in the presence of a normal fetal echocardiogram and cardiac examination, should (...) syndrome (TS) with or without aortic dissection (AoD). Data were derived from references 39 and 54. Dots represent measurements determined by transthoracic echocardiography performed at study entry to the Healthy Heart Project during the annual meeting of the Turner Syndrome Society of the United States between 2003 and 2015 (n=458). For those who were ≥15 years of age (n= 212), the mean body surface area (BSA) was 1.62 m 2 and the mean absolute aortic size was 2.6±0.4 cm. At the time the study

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2018 American Heart Association

182. Use of Imaging Prior to Referral to a Musculoskeletal Oncologist

the history, examination, and imaging is not concerning, and support assertive use of resources in situations where they are clinically necessary. POTENTIAL BENEFITS, HARMS, AND CONTRAINDICATIONS This document potentially benefits providers, patients, and third parties. To providers, it can give some guidance in managing a difficult and potentially high-risk condition. For patients, it can assist in minimizing unnecessary or costly imaging, and ensure that conditions that warrant a more assertive (...) diagnostic strategy are recognized with mitigation of potential barriers. For payers and policy makers, it can provide a summary of the current state of evidence and expert opinion on this topic. One potential risk is that the defined criteria may not capture the minutiae of each individual presentation of musculoskeletal neoplasia. Practitioners must take many factors into account, and these guidelines only address specific features that one may obtain from a history, physical examination, and basic

2018 American Academy of Orthopaedic Surgeons

183. Guidelines for the diagnosis, prevention and management of cryptococcal disease in HIV-infected adults, adolescents and children

and to obtain permission from the copyright holder. The risk of claims resulting from infringement of any third-party-owned component in the work rests solely with the user. General disclaimers. The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of WHO concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted (...) antigen assay can be used in conjunction with histopathological examination and/or culture of appropriate tissue or body fluid samples and exclusion of other diagnoses. India ink microscopy examination

2018 World Health Organisation HIV Guidelines

184. EANM practical guidance on uncertainty analysis for molecular radiotherapy absorbed dose calculations

) given in the GUM to the MIRD schema. This guidance document is presented in the form of an uncertainty propagation schema, and the recommendations are designed to be implemented with the resources available in all nuclear medicine departments offering radionuclide therapy, and are presented using terminology and nomenclature that adhere as far as possible to the GUM. The uncertainty propagation schema examines each step of the absorbed dose calculation to estimate the standard uncertainty (...) imaging approach or those used to generate 3D dose maps. Theory The law of propagation of uncertainty A generic multivariate measurement model is: $$ \boldsymbol{Y}=\boldsymbol{f}\left(\boldsymbol{X}\right), $$ (1) where $$ \boldsymbol{X}={\left[{X}_1,\dots, {X}_n\right]}^{\top } $$ (2) is a vector of n generic input quantities X 1 , …, X n and $$ \boldsymbol{Y}={\left[{Y}_1,\dots, {Y}_m\right]}^{\top } $$ (3) is a vector measurand of m output quantities Y 1 , …, Y m . GUM Supplement 2 [ ] gives

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2019 European Association of Nuclear Medicine

185. Guideline: counselling of women to improve breastfeeding practices

of any opinion whatsoever on the part of WHO concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers ’ products does not imply that they are endorsed or recommended by WHO in preference to others of a similar nature (...) of health systems by defining the expected services and competencies of staff. This guideline examines the evidence and makes recommendations and remarks on the implementation of some of the details of breastfeeding counselling, such as frequency, timing, mode and provider of breastfeeding counselling, to improve breastfeeding practices. The scope of the guideline is limited to this intervention. This guideline does not aim to be a comprehensive guide on all potential interventions that can protect

2018 World Health Organisation Guidelines

186. Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency

glucocorticoids. (1|⊕⊕⊕○) Monitoring therapy 4.12 In patients ≤18 months with congenital adrenal hyperplasia, we recommend close monitoring in the first 3 months of life and every 3 months thereafter. After 18 months, we recommend evaluation every 4 months. (1|⊕⊕○○) 4.13 In pediatric patients with congenital adrenal hyperplasia, we recommend conducting regular assessments of growth velocity, weight, blood pressure, as well as physical examinations in addition to obtaining biochemical measurements to assess (...) the adequacy of glucocorticoid and mineralocorticoid. (1|⊕⊕○○) 4.14 In pediatric patients with congenital adrenal hyperplasia under the age of 2 years, we advise annual bone age assessment until near-adult height is attained. (Ungraded Good Practice Statement) 4.15 In adults with congenital adrenal hyperplasia, we recommend annual physical examinations, which include assessments of blood pressure, body mass index, and Cushingoid features in addition to obtaining biochemical measurements to assess

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2018 Pediatric Endocrine Society

187. HTA of extending the HPV vaccination to boys

to undertake the HTA following a formal request from the Department of Health. The HTA aimed to establish the clinical and cost-effectiveness of extending the current immunisation programme, which offers the 4-valent HPV vaccine to all girls in their first year of second-level education (12 to 13 year olds), to a programme that includes boys. The HTA also examined the organisational, societal and ethical implications of the proposed change. HIQA’s advice to the National Immunisation Office (NIO (...) on the cost-effectiveness of HPV vaccination in males ? perform an economic evaluation of extending the current immunisation programme to include HPV vaccination of boys ? examine the effect of different HPV vaccine uptake rates among girls on the clinical and cost-effectiveness of extending the immunisation programme to boys ? estimate the budget impact of any changes to the current immunisation programme ? estimate the organisational and resource implications of any changes to the current immunisation

2018 Health Information and Quality Authority

188. Guidelines for the Economic Evaluation of Health Technologies in Ireland

-funded health and social care system in Ireland should be adopted when assessing costs. All health benefits accruing to individuals should be included in the assessment of outcomes. The perspective of a study is the viewpoint from which the study is conducted (for example, public payer, individual, society). This defines whose costs, resources and consequences should be examined. To ensure comparability of analyses, this perspective must be clearly stated so that the costs, resources and consequences

2018 Health Information and Quality Authority

189. QTc Prolongation and Psychotropic Medications

reserved. date, studies examining QTc interval prolongation effect for fluoxetine, fluvoxamine and paroxetine have provided no compelling evidence of QTc interval prolongation (30). Sertraline remains the agent with the best-established track record in cardiac populations (31, 32) As previously stated, on August 2011, the United States Food and Drug Administration (FDA) issued a warning for QTc interval prolongation with citalopram based on a thorough QTc interval study demonstrating prolongation (...) , and to use doses of 20mg or lower in patients over the age of 65 years or with liver dysfunction. Though most studies suggest that the risk of QTc interval prolongation and TdP increases with higher doses, at least one large study found higher doses to be associated with fewer adverse outcomes, though QTc interval was not specifically examined and the authors did not control for other known risk factors (37). Several studies have suggested that escitalopram may have QTc interval prolonging properties

2018 American Psychiatric Association

190. Paediatric Urology

. Enhanced urinalysis improves identification of febrile infants ages 60 days and younger at low risk for serious bacterial illness. Pediatrics, 2001. 108: 866. 346. Mayo, S., et al. Clinical laboratory automated urinalysis: comparison among automated microscopy, flow cytometry, two test strips analyzers, and manual microscopic examination of the urine sediments. J Clin Lab Anal, 2008. 22: 262. 347. Kass, E.H. Asymptomatic infections of the urinary tract. Trans Assoc Am Physicians, 1956. 69: 56. 348

2018 European Association of Urology

191. Male Sexual Dysfunction

. 46. Farag, Y.M., et al. Vitamin D deficiency is independently associated with greater prevalence of erectile dysfunction: The National Health and Nutrition Examination Survey (NHANES) 2001-2004. Atherosclerosis, 2016. 252: 61. 47. Caretta, N., et al. Hypovitaminosis D is associated with erectile dysfunction in type 2 diabetes. Endocrine, 2016. 53: 831. 48. Glina, S., et al. Modifying risk factors to prevent and treat erectile dysfunction. J Sex Med, 2013. 10: 115. 49. Vlachopoulos, C., et al (...) Deficiency: Recommendations From the Fourth International Consultation for Sexual Medicine (ICSM 2015). J Sex Med, 2016. 13: 1787. 92. Davis-Joseph, B., et al. Accuracy of the initial history and physical examination to establish the etiology of erectile dysfunction. Urology, 1995. 45: 498. 93. Ghanem, H.M., et al. SOP: physical examination and laboratory testing for men with erectile dysfunction. J Sex Med, 2013. 10: 108. 94. Bhasin, S., et al. Testosterone therapy in men with androgen deficiency

2018 European Association of Urology

192. Management of Non-neurogenic Male LUTS

have bladder outlet obstruction?: The Rational Clinical Examination: a systematic review. JAMA, 2014. 312: 535. 33. Bryan, N.P., et al. Frequency volume charts in the assessment and evaluation of treatment: how should we use them? Eur Urol, 2004. 46: 636. 34. Gisolf, K.W., et al. Analysis and reliability of data from 24-hour frequency-volume charts in men with lower urinary tract symptoms due to benign prostatic hyperplasia. Eur Urol, 2000. 38: 45. 35. Cornu, J.N., et al. A contemporary assessment (...) and validation of diary content, format, and duration. Neurourol Urodyn, 2011. 30: 348. 40. Yap, T.L., et al. A systematic review of the reliability of frequency-volume charts in urological research and its implications for the optimum chart duration. BJU Int, 2007. 99: 9. 41. Weissfeld, J.L., et al. Quality control of cancer screening examination procedures in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. Control Clin Trials, 2000. 21: 390s. 42. Roehrborn, C.G. Accurate

2018 European Association of Urology

193. Recurrent corneal erosion

membrane Prevalence greatest between third and fourth decade Initial cause may have been traumatic, but underlying epithelial dystrophy may be present Repair of epithelial basement membrane takes around three months if largely undisturbed Predisposing factors History of superficial trauma Corneal dystrophy (especially Map-Dot-Fingerprint Dystrophy [Epithelial Basement Membrane or Cogan’s Dystrophy]) Posterior marginal blepharitis (Meibomian gland dysfunction) Diabetes Previous refractive surgery (...) (particularly PRK) Symptoms Unilateral sharp pain, typically sudden onset on waking and opening eyes; may also awake patient in middle of night Feeling as if eyelid is stuck to eyeball Lacrimation Photophobia Blurred vision May recur over weeks, months or years Signs Epithelial erosion (usually inferior cornea) stains with fluorescein ‘loose’ edges, ‘slipped rug’ appearance Intra-epithelial microcysts Mild stromal oedema NB: examine both eyes for signs of corneal dystrophy Differential diagnosis Tear

2018 College of Optometrists

196. Asset-based approaches in service settings: striking a balance

recognised that to achieve a fair and equitable Scotland with positive outcomes for all, there is a need to re-examine both the structural causes of inequality and poverty and the role that public services play in alleviating and reducing their impacts 16 . Examining current issues in terms of asset-based approaches may allow us to think differently about the dynamics between the state and the citizen, and the relationship between service providers and people using services 16 . This shift in Scottish

2017 Glasgow Centre for Population Health

197. Active travel in Glasgow: what we?ve learned so far

the intake of air pollution, leading to negative health consequences. This was examined in a recent study 33 which found that, in most urban environments k , the benefits from undertaking physical activity outweighed risks from air pollution. Short motor vehicle journeys make a disproportionate contribution to overall air pollution levels partly because over half of all car journeys are five miles or shorter 34 , and partly because emissions are highest when the engine is first started and gradually

2017 Glasgow Centre for Population Health

199. WHO Guidelines on Integrated Care for Older People (ICOPE)

with the user. General disclaimers. The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of WHO concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain

2017 World Health Organisation Guidelines

200. Preventive chemotherapy to control soil-transmitted helminth infections in at-risk population groups

infringement of any third-party-owned component in the work rests solely with the user. General disclaimers. The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of WHO concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may (...) –2010 and strategic plan 2011–2020 (9). Population of interest The guideline will affect young children (12-23 months of age), preschool (24-59 months of age) and school- age children, 2 adolescent girls (10–19 years of age), women of reproductive age (15–49 years of age) and pregnant women in any health-care and community setting. Special considerations for children, adolescents and women living with HIV will be examined, as will deworming for pregnant women as it relates to outcomes related

2017 World Health Organisation Guidelines

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