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121. Perineural cyst with intracystic hemorrhage following aneurysmal subarachnoid hemorrhage: A case report. (PubMed)

Perineural cyst with intracystic hemorrhage following aneurysmal subarachnoid hemorrhage: A case report. Most perineural cysts are asymptomatic and discovered incidentally at the time of imaging. Although enlargement of the perineural cyst (PC) through a ball-valve mechanism and resultant compression of the adjacent neural or bony structures are known to be a source of pain in PCs, the reason why asymptomatic PCs become symptomatic is unclear. The authors report a case of PC, which was presumed

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2019 Medicine

122. Helicobacter cinaedi Hepatic Cyst Infection with Bacteremia. (PubMed)

Helicobacter cinaedi Hepatic Cyst Infection with Bacteremia. Helicobacter cinaedi is an enterohepatic bacillus that causes infections of various manifestations. We report a novel case of hepatic cyst infection with bacteremia caused by H. cinaedi in an immunocompetent woman in Japan. Further research is warranted to identify the epidemiologic and clinical features of H. cinaedi infection.

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2019 Emerging Infectious Diseases

123. Cyst Fluid Biosignature to Predict Intraductal Papillary Mucinous Neoplasms of the Pancreas with High Malignant Potential. (PubMed)

Cyst Fluid Biosignature to Predict Intraductal Papillary Mucinous Neoplasms of the Pancreas with High Malignant Potential. Current standard-of-care technologies such as imaging and cyst fluid analysis are unable to consistently distinguish intraductal papillary mucinous neoplasms of the pancreas (IPMN) at high-risk of pancreatic cancer from low-risk IPMN. The objective was to create a single-platform assay to identify IPMN that are at high-risk for malignant progression.Building on the Verona (...) International Consensus Conference BD-IPMN biomarker study, specific protein, cytokine, mucin, DNA, and miRNA cyst fluid targets were identified for creation of a q-PCR based assay as we have previously published. This included mRNA markers: ERBB2, GNAS, IL1b, KRAS, MUCs1, 2, 4, 5AC, 7, PGE2R, PTGER2, PTGES2, PTGES1, TP63; miRNA targets: miRs 101, 106b, 10a, 142, 155, 17, 18a, 21, 217, 24, 30a, 342, 532, 92a, and 99b; and GNAS and KRAS mutational analysis. A multi-institutional international collaborative

2019 Journal of the American College of Surgeons

124. Removal of an infant's gastric duplication cyst through endoscopic submucosal dissection: A case report. (PubMed)

Removal of an infant's gastric duplication cyst through endoscopic submucosal dissection: A case report. Gastric duplication cyst is an anomaly that primarily occurs to children. Apart from the conventional use of surgical resection, few cases using endoscopic treatment have been reported.A 5-month-old female infant was hospitalized with the chief complaint of gastric cyst. No significant abnormalities were identified by physical examination.Endoscopic submucosal dissection (ESD) was performed (...) successfully for the infant and the duration was less than 20 minutes. The patient showed no postoperative complications.At 4 months during the follow-up, upper endoscopy revealed a small scar at the previous site of the lesion and no recurrence.According to the results of PUBMED review, she was the youngest with gastric duplication cyst removed with ESD. The less invasive ESD should be considered an effective therapeutic option to remove gastric duplication cyst in children.

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2019 Medicine

125. Incidence and Risk Factors for Meniscal Cyst After Meniscal Repair. (PubMed)

Incidence and Risk Factors for Meniscal Cyst After Meniscal Repair. To investigate the incidence of magnetic resonance imaging-confirmed cyst formation after meniscal repair and to analyze associated risk factors.This retrospective study included cases repaired arthroscopically with the all-inside (AI) technique (using suture anchors) and/or the inside-out (IO) technique between October 2008 and December 2014. A meniscal cyst was detected on T2 fat-suppressed magnetic resonance images. All (...) cases were divided into 3 groups according to the repair method (AI, IO, and combined technique). The incidence of radiographically confirmed meniscal cyst formation in each group and the associated risk factors (age, sex, AI device, medial meniscus, Tegner activity scale preinjury) were analyzed.A total of 102 menisci in 96 knees were evaluated. The mean follow-up period was 3.8 (range, 2-8) years. The mean patient age was 21.0 (range, 6-53) years. Thirty cases were in the AI group, 60 in the IO

2019 Arthroscopy

126. The histological properties and possible origin of cervical thymus with cysts - A case report and hypotheses about its development. (PubMed)

The histological properties and possible origin of cervical thymus with cysts - A case report and hypotheses about its development. Ectopic accessory thymic tissue usually presents as an asymptomatic neck mass found at any level corresponding to the embryonic descent of the thymus. This tissue may contain smaller or larger cysts. However, the exact pathogenesis of "enigmatic" cervical thymic cysts remains controversial. A 7-year-old boy was referred to our workplace for the evaluation (...) a place for development of T-lymphocytes. Within the parenchyma multiple cysts lined with cytokeratin-positive thymic epithelial cells were found. Inside the cysts, there were CD68-positive multinucleated giant cells and cholesterol clefts. A tendency to cystic degeneration inside the thymic tissue occurs more often in cervical thymuses than in normally located ones. The reason for the formation of cysts is unknown. We summarized seven possible histological, embryological and evolutional backgrounds

2019 International Journal of Pediatric Otorhinolaryngology

127. Editorial Commentary: Acetabular Paralabral Cysts…It's All About Location, Location, Location…. (PubMed)

Editorial Commentary: Acetabular Paralabral Cysts…It's All About Location, Location, Location…. With our increased understanding about the causes of young adult hip pain and femoroacetabular impingement, magnetic resonance imaging has become an important diagnostic tool for identifying labral pathology. However, arthroscopic evaluation is paramount to understanding whether a labral tear truly exists in these patients. Orthopaedic dogma suggests that acetabular paralabral cysts form due (...) to an associated acetabular labral tear. Nevertheless, a cause and effect relationship has not yet been proven in the literature. The location of these paralabral cysts may influence the clinical symptoms that they cause and their diagnostic utility. Further work is needed to fully understand the relevance of acetabular paralabral cysts in patients with femoroacetabular impingement.Copyright © 2019 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

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2019 Arthroscopy

128. Case report: a novel mutation in ZIC2 in an infant with microcephaly, holoprosencephaly, and arachnoid cyst. (PubMed)

Case report: a novel mutation in ZIC2 in an infant with microcephaly, holoprosencephaly, and arachnoid cyst. Holoprosencephaly (HPE) is a severe congenital brain malformation resulting from failed or incomplete forebrain division in early pregnancy.In this study, we reported a 9-month old infant girl with mild microcephaly, semilobor HPE, and arachnoid cyst.Potential genetic defects were screened directly using trio-case whole exome sequencing (WES) rather than traditional karyotype, microarray (...) findings expanded the spectrum of the ZIC2 gene mutations and associated clinical manifestations, which is the first identification of a mutated ZIC2 gene in a Han infant girl with mild microcephaly, semilobor HPE, and arachnoid cyst.

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2019 Medicine

129. Symptomatic aneurysmal bone cysts of the spine: clinical features, surgical outcomes, and prognostic factors. (PubMed)

Symptomatic aneurysmal bone cysts of the spine: clinical features, surgical outcomes, and prognostic factors. The aim of the study was to report the long-term outcomes and analyze the potential prognostic factors that may contribute to symptomatic patients with aneurysmal bone cyst (ABC) of the spine undergoing surgical treatments.A retrospective analysis of consecutive patients with ABCs of the spine was performed. The clinical features were reviewed, and the disease-free survival (DFS

2019 European Spine Journal

130. Healing of human critical-size alveolar bone defects secondary to cyst enucleation: a randomized pilot study with 12 months follow-up. (PubMed)

Healing of human critical-size alveolar bone defects secondary to cyst enucleation: a randomized pilot study with 12 months follow-up. Alveolar bone cyst enucleation can give rise to critical-size defects whose healing may be incomplete due to the loss of periosteum or bone walls and there is a paucity of studies investigating the use of immediate bone grafts. The aim of this study was to compare spontaneous healing versus a deproteinized bovine bone graft.In this prospective randomized (...) clinical pilot study, twenty patients requiring the removal of a cyst ≥20 mm in maximum diameter were randomly assigned to one of two groups: deproteinized bovine bone grafting (test) or spontaneous healing (control). Computed tomographies were obtained preoperatively and 12 months after surgery and the radiolucent volumes were compared. Residual radiological morphology and clinical outcomes at 7 days and 1, 6 and 12 months after surgery were also assessed.The median percentage reduction in the volume

2019 Minerva stomatologica Controlled trial quality: uncertain

131. Comparison of elliptical excision versus punch incision for the treatment of epidermal inclusion cysts: A prospective, randomized study. (PubMed)

Comparison of elliptical excision versus punch incision for the treatment of epidermal inclusion cysts: A prospective, randomized study. 29229572 2019 01 03 2019 01 03 1097-6787 79 2 2018 Aug Journal of the American Academy of Dermatology J. Am. Acad. Dermatol. Comparison of elliptical excision versus punch incision for the treatment of epidermal inclusion cysts: A prospective, randomized study. 360-361 S0190-9622(17)32765-2 10.1016/j.jaad.2017.12.011 Cheeley Justin J Department of Dermatology (...) Trial 2017 12 09 United States J Am Acad Dermatol 7907132 0190-9622 IM Aged Epidermal Cyst surgery Female Humans Male Middle Aged Patient Satisfaction Postoperative Complications epidemiology Prospective Studies Single-Blind Method Surgical Wound Treatment Outcome 2017 08 30 2017 11 30 2017 12 04 2017 12 13 6 0 2019 1 4 6 0 2017 12 13 6 0 ppublish 29229572 S0190-9622(17)32765-2 10.1016/j.jaad.2017.12.011

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2019 Journal of the American Academy of Dermatology Controlled trial quality: uncertain

132. Preoperative ultrasound for the diagnosis of thyroglossal duct cysts: A validation study. (PubMed)

Preoperative ultrasound for the diagnosis of thyroglossal duct cysts: A validation study. To evaluate the use of ultrasound to distinguish between thyroglossal duct cysts (TGDC) and dermoid cysts (DC) for surgical planning. To validate the SIST (septae + irregular wall + solid components = TGDC) scoring system proposed by Oyewumi et al. [1].This was a retrospective chart review of pediatric patients with midline neck masses who presented between the years of 2005 and 2014 and underwent

2019 International Journal of Pediatric Otorhinolaryngology

133. Atypical thyroglossal duct cyst with intra-laryngeal and para-glottic extension. (PubMed)

Atypical thyroglossal duct cyst with intra-laryngeal and para-glottic extension. Thyroglossal duct cysts (TDC) are the most common congenital neck masses. Although they are anatomically closely related to the larynx, intra-laryngeal extension is very rare. We present a case, review the literature and discuss the challenges of intra-laryngeal TDC. A 55-year-old man presented with a neck mass associated with dysphagia. Computer Tomography neck scan showed a midline cyst extending to the pre (...) -epiglottic space with partial obliteration of the right pyriform sinus and narrowing of the larynx. The cyst was excised en-bloc via Sistrunk procedure. Intra-laryngeal TDC are surgically challenging due to risk of perforation into the aerodigestive tract.Copyright © 2019 Elsevier Inc. All rights reserved.

2019 American Journal of Otolaryngology

134. Preventing Restenosis of Marsupialized Rathke Cleft Cysts Using a Nasoseptal Flap Lining. (PubMed)

Preventing Restenosis of Marsupialized Rathke Cleft Cysts Using a Nasoseptal Flap Lining. Rathke cleft cysts (RCCs) are rare, benign lesions formed from remnants of Rathke pouch during embryologic development. However, following marsupialization, maintaining tract patency remains a challenge. Several techniques for decreasing stenosis have been described, including free mucosal grafting, silastic spacing, and using steroid-eluting stents. Nasoseptal flaps (NSFs) have a reliable vascular supply (...) symptomatic control, surgical complications, and RCC cavity patency.Seven patients underwent RCC marsupialization with no intraoperative cerebrospinal fluid leak, followed by circumferential lining of the marsupialized cavity with an NSF. In each case, no cyst re-accumulation or recurrent symptoms were noted, and the NSF lining provided long-term patency of the tract in all cases to a mean of 6.7 ± 10.1 months of follow-up, including one patient with sustained patency at 29 months follow-up.Utilization

2019 Laryngoscope

135. Incidence and clinical predictors of cystic squamous cell carcinoma metastases in lateral cervical cysts. (PubMed)

Incidence and clinical predictors of cystic squamous cell carcinoma metastases in lateral cervical cysts. This study aimed to determine the incidence of metastatic squamous cell carcinoma in patients with an isolated cervical cystic mass, and to describe the clinical features that might predict the origin of cystic tumours.Adult patients with isolated lateral cervical cystic masses who were scheduled for surgery from 1st January 2010 to 31st August 2016 in two tertiary care referral centres (...) in Slovakia were analysed retrospectively.The incidence of cystic metastases in the whole cohort and in patients aged over 40 years were 9.9 per cent and 18.5 per cent, respectively. The incidence in patients aged over 40 years (18.5 per cent) was statistically significant (p = 0.003).The incidence of cystic squamous cell carcinoma metastases in lateral cervical cysts in patients aged over 40 years is high enough to call for excisional biopsy with frozen section, panendoscopy with direct biopsies

2019 Journal of Laryngology & Otology

136. Cyst Ventilation Heterogeneity and Alveolar-Airspace Dilation as Early Disease Markers in Lymphangioleiomyomatosis. (PubMed)

Cyst Ventilation Heterogeneity and Alveolar-Airspace Dilation as Early Disease Markers in Lymphangioleiomyomatosis. Lymphangioleiomyomatosis (LAM) is a rare disease associated with cystic destruction of the pulmonary parenchyma and chronic respiratory failure, and there are trials underway to determine if early intervention can prevent disease progression. An imaging technique that is sensitive to early regional disease would therefore be valuable for patient care and clinical trials.We (...) postulated that hyperpolarized 129Xe MRI would be sensitive to ventilation abnormalities and alveolar-airspace dilation in patients with mild LAM disease and normal pulmonary function and that 129Xe MRI would reveal important features of cyst ventilation.129Xe ventilation and diffusion-weighted MR images were acquired in 22 LAM patients during two breath-holds of hyperpolarized 129Xe. 129Xe ventilation defect percentage (VDP; percentage of voxels <60% of the mean whole-lung 129Xe MRI signal) and apparent

2019 Annals of the American Thoracic Society

137. Laparoscopic management for aberrant hepatic duct in children with choledochal cysts. (PubMed)

Laparoscopic management for aberrant hepatic duct in children with choledochal cysts. The aim of the current study is to evaluate efficacy of laparoscopic treatment for aberrant hepatic duct (AHD) in children with cholecochal cysts (CDC).CDC children with AHDs who successfully underwent laparoscopic ductoplasties and hepaticojejunostomies between October 2001 and October 2017 were reviewed. The AHD variations were categorized into four subtypes and the surgical management varied according (...) patients with giant cysts had fluid collections, and were cured by drainages. One patient encountered duodenal injury at perforation site, and underwent laparoscopic repair. None of the patients had anastomotic stenosis, bile leak, cholangitis, intrahepatic reflux, pancreatic leak, pancreatitis, Roux-loop obstruction, or adhesive intestinal obstruction. Postoperative liver function tests and serum amylase level normalized within 1 year.Recognition and treatment based on different subtypes of AHDs

2019 Surgical endoscopy

138. Renal cell carcinoma originating in the free wall of simple renal cyst: Two unusual case reports with literature review. (PubMed)

Renal cell carcinoma originating in the free wall of simple renal cyst: Two unusual case reports with literature review. Simple renal cyst (SRC) is a benign disease. However, rarely renal cell carcinoma (RCC) may be raised at the wall of a preexisting SRC. We herein describe 2 unusual cases of RCC arising from the outer surface of the free wall of the renal cyst.A 75-year-old female and a male were admitted to our department because of an asymptomatic renal cystic mass. Although the case (...) history, preoperative imaging, and intraoperative examination of the cyst were carefully evaluated, no concerns were raised with respect to the underlying malignancy.RCC of the clear cell type was diagnosed based on the histology and pathological examination.With an initial diagnosis of SRC, the retroperitoneal laparoscopic de-roofing of the SRC was performed in both of the patients. When the diagnoses were confirmed 7 days postoperative, both of them were readmitted to our department for a radical

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2019 Medicine

139. Thyroid Rosai-Dorfman disease with infiltration of IgG4-bearing plasma cells associated with multiple small pulmonary cysts. (PubMed)

Thyroid Rosai-Dorfman disease with infiltration of IgG4-bearing plasma cells associated with multiple small pulmonary cysts. Rosai-Dorfman disease (RDD) is a rare histiocytosis which involves principally lymph nodes. Thyroid involvement in RDD is a very rare situation, and lung involvement is even rarer.We report the case of a 46-year-old woman presenting a painless mass in the right side of the neck and subacute dyspnoea. Computerised tomography (CT) scans of the neck and thorax showed a large (...) indicates a benign course of nodal RDD with thyroid and tracheal infiltration following surgical resection, association of typical histological signs of RDD (emperipolesis) with IgG4-related disease features, and that lung cysts might be a manifestation of RDD.

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2019 BMC pulmonary medicine

140. Endoscopic removal of recurrent colloid cysts. (PubMed)

Endoscopic removal of recurrent colloid cysts. OBJECTIVERemoval of colloid cysts of the third ventricle using a purely endoscopic method has been established as a safe and advantageous technique. It is hypothesized that endoscopic removal in recurrent cases might pose more technical challenges and result in less success. The objective of this study was to assess the feasibility and outcomes of using a purely endoscopic approach for the management of recurrent colloid cysts compared to primary (...) cysts.METHODSA retrospective cohort study was performed on patients who underwent purely endoscopic removal of their colloid cyst. Descriptive statistics were compared for patients undergoing surgery for a recurrent cyst and those for a control cohort undergoing surgery for a primary cyst. Bivariate analysis was conducted using a Fisher's exact test for categorical variables and Mann-Whitney U-test for continuous variables.RESULTSIn total, 121 patients had a primary colloid cyst endoscopically removed and 10

2019 Journal of Neurosurgery

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