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Cyst

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21901. Reduced kidney size in patients with simple renal cysts. Full Text available with Trip Pro

Reduced kidney size in patients with simple renal cysts. Renal cysts frequently occur in the absence of genetic diseases but their significance is unknown. Since multiple cysts develop in many patients with advanced renal disease, we tested the hypothesis that isolated cysts are associated with early nephron loss.All inpatient and outpatient sonograms performed by the Renal Division since 1995 were reviewed and, after exclusion of duplicate studies, patients with genetic cystic disorders (...) , complex cysts, hydronephrosis, peripelvic cysts, end-stage renal disease and transplanted kidneys, 2526 were selected for this study, of which 385 had one or more cysts. Maximum renal length was used as an indication of size, and renal function was estimated by serum creatinine concentration.Both right and left kidney length were significantly less in patients with cysts (P < 0.0001), independent of which kidney contained the cyst(s). Renal lengths were less in patients with multiple cysts as opposed

2003 Kidney International

21902. Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys. Full Text available with Trip Pro

Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys. The proliferation of mural epithelial cells is a major cause of progressive cyst enlargement in autosomal-dominant polycystic kidney disease (ADPKD). Adenosine 3', 5' cyclic monophosphate (cAMP) stimulates the proliferation of cells from ADPKD cysts, but not cells from normal human kidney cortex (HKC), through the activation of protein kinase A (PKA), mitogen-activated protein kinase kinase (...) cascade. Consequently, cAMP and EGF have great potential to accelerate the progressive enlargement of renal cysts.

2003 Kidney International

21903. Fatal Clostridium perfringens infection of a liver cyst. (Abstract)

Fatal Clostridium perfringens infection of a liver cyst. We report a case of Clostridium perfringens infection of a pre-existing hepatic cyst leading to a fatal outcome.

2003 Journal of Infection

21904. Acanthamoeba polyphaga strain age and method of cyst production influence the observed efficacy of therapeutic agents and contact lens disinfectants. Full Text available with Trip Pro

Acanthamoeba polyphaga strain age and method of cyst production influence the observed efficacy of therapeutic agents and contact lens disinfectants. The effects of age in culture and the type of medium used for induction of Acanthamoeba polyphaga (Ros) cysts on susceptibilities to polyhexamethylene biguanide (PHMB; 3 micro g/ml), chlorhexidine digluconate (30 micro g/ml), myristamidopropyl dimethylamine (20 micro g/ml), H(2)O(2) (3%), and two multipurpose contact lens solutions (MPS-1 and MPS (...) -2, based on 1 micro g of PHMB per ml) were examined. Strain Ros-02 was cryopreserved on isolation in 1991, while strain Ros-91 had been in continuous axenic culture. Significant differences in susceptibilities to the disinfectants were found depending on the medium used for cyst preparation and the age of the test strain, with Ros-02 generally being more resistant. For example, the killing of Ros-91 cysts produced from an axenic culture of trophozoites in the presence of 50 mM MgCl(2) by MPS-2

2003 Antimicrobial Agents and Chemotherapy

21905. Cyst-like cerebral lesions in tuberous sclerosis. (Abstract)

Cyst-like cerebral lesions in tuberous sclerosis. Known brain manifestations of tuberous sclerosis (TSC) are cortical sclerotic tubera, giant cell astrocytomas, subependymal calcified nodules in the lateral walls of the lateral ventricles, and white matter heterotopias. In addition, small cyst-like lesions in the white matter have been described. We report on three TSC patients with hitherto undescribed large cyst-like cerebral lesions in subcortical and white matter locations. We emphasize

2002 American Journal of Medical Genetics

21906. Iatrogenic candidal infection of a mediastinal foregut cyst following endoscopic ultrasound-guided fine-needle aspiration. (Abstract)

Iatrogenic candidal infection of a mediastinal foregut cyst following endoscopic ultrasound-guided fine-needle aspiration. EUS-guided fine-needle aspiration (EUS-FNA) is a safe procedure with few complications. We describe the introduction of Candida into a mediastinal foregut cyst following trans-oesophageal EUS-FNA, and discuss the implications of this complication.

2002 Endoscopy

21907. Mediastinitis caused by EUS-FNA of a bronchogenic cyst. (Abstract)

Mediastinitis caused by EUS-FNA of a bronchogenic cyst. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a safe and minimally invasive diagnostic technique for the analysis of mediastinal lesions. This case report describes a patient who developed a life-threatening mediastinitis after EUS-FNA of a mediastinal lesion, which (based on computed tomography of the thorax) had been suspected to be a lymph-node metastasis, but proved to be a bronchogenic cyst.

2003 Endoscopy

21908. Branchial cyst, sensorineural deafness, congenital heart defect, and skeletal abnormalities: Branchio-oto-cardio-skeletal (BOCS) syndrome? (Abstract)

Branchial cyst, sensorineural deafness, congenital heart defect, and skeletal abnormalities: Branchio-oto-cardio-skeletal (BOCS) syndrome? This article describes a boy with an unusual combination of features, namely, intrauterine growth retardation, short stature, branchial cyst, sensorineural hearing loss, congenital heart defect, rib and vertebral abnormalities, micromelia, brachymesophalangia, and absence of phalanges. We suggest that these findings comprise a new entity of combined branchio

2002 American Journal of Medical Genetics

21909. Rapidly growing sublingual dermoid cyst throughout pregnancy. (Abstract)

Rapidly growing sublingual dermoid cyst throughout pregnancy. Dermoid cysts (DCs) are subcutaneously located cystic masses that contain epithelium and adnexal structures. They are most commonly located in the ovaries and sacral region. Seven percent of DCs are found in the head and neck. Sublingual DCs may develop above the mylohyoid, presenting in the floor of the mouth or below it, causing a submental or submaxillary mass. We presented a case with a sublingual giant DC enlarged rapidly during

2003 American Journal of Otolaryngology

21910. Posterior fossa arachnoid cysts can mimic Meniere's disease. (Abstract)

Posterior fossa arachnoid cysts can mimic Meniere's disease. Arachnoid cysts constitute 1% of all intracranial space-occupying lesions. In the posterior fossa, they typically produce vague, nonspecific symptoms. However, a subset of these lesions can produce signs and symptoms indistinguishable from those of Meniere's disease. We discuss the clinical and laboratory features of 2 cases of posterior fossa arachnoid cysts mimicking Meniere's disease as well as the substantial resolution (...) of symptoms in 1 patient after cysto-peritoneal shunt. Posterior fossa arachnoid cyst must be considered in the differential diagnosis of patients presenting with signs and symptoms of Meniere's disease.

2003 American Journal of Otolaryngology

21911. Ganglion cyst of the spinal anterior longitudinal ligament presenting as a retropharyngeal mass. (Abstract)

Ganglion cyst of the spinal anterior longitudinal ligament presenting as a retropharyngeal mass. Cervical spinal synovial and/or ganglion cysts can occur at various periarticular sites and should be considered in the differential diagnosis of intraspinal-extradural or paraspinal masses of the cervical spine. The first report of a ganglion cyst of the cervical anterior longitudinal ligament presenting as a retropharyngeal mass, is presented. The histopathology, etiology, and clinical aspects (...) of synovial and ganglion cysts of the cervical spine are briefly reviewed.Copyright 2002, Elsevier Science (USA). All rights reserved.)

2002 American Journal of Otolaryngology

21912. Neuroepithelial cysts of the middle ear. (Abstract)

Neuroepithelial cysts of the middle ear. Neuroepithelial cysts are lesions of the central nervous system that have previously been reported in cerebral parenchyma, in the spinal cord, and within the ventricles in association with the choroid plexus. We describe 2 cases of neuroepithelial cysts of the middle ear. One was diagnosed after surgery for a retraction pocket and chronic otitis media complicated by an intraoperative cerebrospinal fluid (CSF) leak. The other produced bilateral (...) spontaneous CSF otorrhea and mimicked the presentation of arachnoid granulations. Both cases were verified with immunohistochemical stains. Neuroepithelial cysts, although rare, should be considered in the differential diagnosis of spontaneous CSF otorrhea or an epitympanic mass.

2003 Rhinology and Laryngology

21913. Subglottic cysts: the Great Ormond Street experience. (Abstract)

Subglottic cysts: the Great Ormond Street experience. Subglottic cysts are a relatively rare, non-malignant cause of airway obstruction. In this study we reviewed the details of the patients who were treated for subglottic cysts in our department in order to evaluate the presentation and treatment of patients with this condition.We performed a retrospective case note analysis of 55 patients with subglottic cysts. Case notes were examined to determine the following details for each patient: date (...) of birth, gestational age at birth, history and length of intubation, age at presentation, presenting symptoms, findings on endoscopy, treatment given for subglottic cysts, recurrence(s) of cysts after initial treatment, and follow up for a minimum of 6 months post diagnosis.Fifty five patients were identified, 35 male, 20 female. Ninety four percent were born prematurely at 24-31 weeks gestation. All patients were intubated in the neonatal period. The median duration of intubation for all patients

2003 International Journal of Pediatric Otorhinolaryngology

21914. Vallecular cyst: a cause of failure to thrive in an infant. (Abstract)

Vallecular cyst: a cause of failure to thrive in an infant. Congenital vallecular cyst is fairly uncommon in neonates and infants. Although benign in nature, it may cause stridor and even life-threatening airway obstruction in early infancy. A 3-month-old male baby presented with failure to thrive and respiratory distress was found to have a vallecular cyst. Marsupialization with CO(2) laser was performed.Copyright 2002 Elsevier Science Ireland Ltd.

2002 International Journal of Pediatric Otorhinolaryngology

21915. A unique case of an epidermoid cyst of the pterygopalatine fossa and its management. (Abstract)

A unique case of an epidermoid cyst of the pterygopalatine fossa and its management. Epidermoid cysts are rare benign tumors that are derived from the development of abnormally situated ectodermal tissue. Although they may originate from any part of the body head and neck region is occasionally affected. Epidermoid cyst originating from pterygopalatine fossa has not been reported previously in the literature. We report the first case of epidermoid cyst of pterygomaxillary fossa in this study.

2003 International Journal of Pediatric Otorhinolaryngology

21916. Thyroglossal duct cysts: presentation and management in children versus adults. (Abstract)

Thyroglossal duct cysts: presentation and management in children versus adults. To determine if the clinical presentation of thyroglossal duct cysts (TGDC) varies between children and adults and whether this knowledge helps optimize the surgical management.We retrospectively identified all patients with TGDC managed in our department between 1992 and 2002. We reviewed the patients' charts and recorded their gender, age at diagnosis, clinical presentation, radiologic imaging, surgical management

2003 International Journal of Pediatric Otorhinolaryngology

21917. Multiple hydatid cysts of the neck, the nasopharynx and the skull base revealing cervical vertebral hydatid disease. (Abstract)

Multiple hydatid cysts of the neck, the nasopharynx and the skull base revealing cervical vertebral hydatid disease. Hydatid disease is caused by the parasitic tapeworm Echinococcus. This parasite in larval stage can thrive in many parts of the body, most commonly in the liver and the lung. Hydatid disease in the head and neck is uncommon and hydatid cyst presents rarely as a cervical mass. Cervical vertebral echinococcosis is rare. We report a 14-year-old girl with multiple cervical spine (...) hydatid cysts of the C1-C2 vertebrae that spread into the surrounding paravertebral tissues and involve the nasopharynx and the skull base particularly the left jugular foramen. This process has caused a progressive swelling in the left side of the neck located in the retrostyloid compartment of the parapharyngeal space with paralysis of cranial nerves (VI, IX, X, XI, XII). The diagnosis was made based on the image obtained from CT and MRI examinations. Characteristics of this rare disease, diagnosis

2003 International Journal of Pediatric Otorhinolaryngology

21918. Intra-thyroid thyroglossal duct cyst as a differential diagnosis of thyroid nodule. (Abstract)

Intra-thyroid thyroglossal duct cyst as a differential diagnosis of thyroid nodule. An intra-thyroid thyroglossal duct cyst (ITTDC) presented as a congenital anterior neck mass in a 10-year-old male. Diagnosis, work-up, management approach, and differential diagnosis of thyroid nodules are discussed, as well as distinguishing features between thyroglossal duct cyst (TDC) and branchial cleft cyst (BCC). This is the fourth case of ITTDC reported in the pediatric population, and ITTDC should

2003 International Journal of Pediatric Otorhinolaryngology

21919. Anterior lingual thyroglossal cyst: antenatal diagnosis, management, and long-term outcome. (Abstract)

Anterior lingual thyroglossal cyst: antenatal diagnosis, management, and long-term outcome. To describe the long-term outcome of a large anterior lingual thyroglossal duct cyst, diagnosed antenatally by ultrasound that completely obstructed the oral cavity and had almost completely replaced the anterior two-thirds lingual musculature.Longitudinal observation.Anticipated airway obstruction at birth did not occur. Complete cyst removal occurred at day 2 of life with a rim of lingual muscle (...) that is critical to deglutition and articulation. Early speech therapy appears key to improving functional outcomes of speech. A strong central nervous system basis for suckle development is suggested by the rapid development of a safe and effective suckle and swallow soon after cyst resection and in spite of in utero tongue fixation.

2003 International Journal of Pediatric Otorhinolaryngology

21920. Psammomatous calcification in association with a benign thyroglossal duct cyst. (Abstract)

Psammomatous calcification in association with a benign thyroglossal duct cyst. Embryologic remnants of thyroid tissue often line the thyroglossal duct tract and may commonly become cystic. Calcification in such a cyst is thought to be a specific marker for malignancy, which may develop in 1% of thyroglossal duct cysts. We describe a 3-year-old boy with a midline neck mass that showed radiologic calcification. Pathologic evaluation revealed psammomatous calcification in association (...) with a benign thyroglossal duct cyst. These findings, not previously reported (to our knowledge), expand the radiologic differential diagnosis of calcified neck masses and broaden the spectrum of pathologic findings seen in association with benign thyroglossal duct cysts.

2003 Archives of Otolaryngology Head and Neck Surgery

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