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Cyanosis

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1. Assessment of cyanosis in the newborn

Assessment of cyanosis in the newborn Assessment of cyanosis in the newborn - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of cyanosis in the newborn Last reviewed: February 2019 Last updated: November 2018 Summary Tachypnoea and cyanosis are frequently encountered in the neonatal period. The prevalence of respiratory distress in newborns ranges from 2.9% to 7.6%. Cyanosis can result from a range (...) of disorders, including cardiac, metabolic, neurological, and pulmonary disorders. In all, 4.3% of newborns may require supplemental oxygen therapy because of cyanosis. Hjalmarson O. Epidemiology and classification of acute neonatal respiratory disorders: a prospective study. Acta Paediatr Scand. 1981 Nov;70(6):773-83. http://www.ncbi.nlm.nih.gov/pubmed/7324931?tool=bestpractice.com Hjalmarson O. Epidemiology of neonatal disorders of respiration. Int J Technol Assess Health Care. 1991;7 Suppl 1:9-15. http

2018 BMJ Best Practice

2. Assessment of cyanosis in the newborn

Assessment of cyanosis in the newborn Assessment of cyanosis in the newborn - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of cyanosis in the newborn Last reviewed: February 2019 Last updated: November 2018 Summary Tachypnoea and cyanosis are frequently encountered in the neonatal period. The prevalence of respiratory distress in newborns ranges from 2.9% to 7.6%. Cyanosis can result from a range (...) of disorders, including cardiac, metabolic, neurological, and pulmonary disorders. In all, 4.3% of newborns may require supplemental oxygen therapy because of cyanosis. Hjalmarson O. Epidemiology and classification of acute neonatal respiratory disorders: a prospective study. Acta Paediatr Scand. 1981 Nov;70(6):773-83. http://www.ncbi.nlm.nih.gov/pubmed/7324931?tool=bestpractice.com Hjalmarson O. Epidemiology of neonatal disorders of respiration. Int J Technol Assess Health Care. 1991;7 Suppl 1:9-15. http

2018 BMJ Best Practice

3. CRACKCast E014 – Cyanosis

CRACKCast E014 – Cyanosis CRACKCast E014 - Cyanosis - CanadiEM CRACKCast E014 – Cyanosis In , by Adam Thomas November 17, 2016 This episode of CRACKCast covers Rosen’s Chapter 014, Cyanosis. Here are some tips for the next time someone comes in to the Emergency Department looking a little blue. Shownotes – Rosen’s in Perspective: Key terms: oxygenated vs. deoxygenated hemoglobin = saturated vs. desaturated hemoglobin SaO2 (arterial oxygen saturation measured/calculated by ABG) SpO2 (peripheral (...) oxygen saturation measured by pulse oximetry) PaO2 PAO2 (partial pressure of O2 in the blood (measured by ABG) vs. partial pressure in the alveolus) Cyanosis = imbalance between oxy/deoxy hemoglobin cyanosis is specific for hypoxia but not sensitive (can be hypoxic without cyanosis!) normal adults that is when deoxy hemoglobin >5g/dl cyanosis is about absolute amount of deoxygenated hemoglobin – anemic individuals turn blue only at lower levels of PaO2 and SaO2 1) What is the differential diagnosis

2016 CandiEM

4. Wide Complex Tachycardia and Cyanosis

Wide Complex Tachycardia and Cyanosis Dr. Smith's ECG Blog: Wide Complex Tachycardia and Cyanosis Tuesday, January 10, 2017 This case was sent by a former HCMC resident: A 20-something non-English speaking woman with a history of some sort of congenital heart defect collapsed at home and EMS found her with a regular wide complex tachycardia around 200 bpm. They attempted cardioversion with adenosine , unsuccessfully (dose was uncertain, thought to be 12 mg, but this would be an unusual initial

2017 Dr Smith's ECG Blog

5. Anomalous Connection of the Right Superior Vena Cava to the Left Atrium in a Child with Bilateral Superior Vena Cavae: An Unusual Cause of Cyanosis. (PubMed)

Anomalous Connection of the Right Superior Vena Cava to the Left Atrium in a Child with Bilateral Superior Vena Cavae: An Unusual Cause of Cyanosis. Anomalous drainage of the right superior vena cava into the left atrium (LA) has been previously reported in the medical literature. We present a unique case of a child who had two superior vena cavae, a left superior vena cava that drained normally through the coronary sinus to the right atrium, and a right superior vena cava that drained

2018 Pediatric Cardiology

6. Carcinoid heart disease revealed by cyanosis with both right and left valvular involvement: a case report (PubMed)

Carcinoid heart disease revealed by cyanosis with both right and left valvular involvement: a case report Carcinoid heart disease is a frequent complication of carcinoid syndrome. It is related to the release by the carcinoid tumor and/or its metastases of bioactive substances such as serotonin. It is characterized by right-sided valvular involvement and can lead to right-sided heart failure. It is a prognostic factor of carcinoid syndrome.We report the case of a 53-year-old African woman

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2018 Journal of medical case reports

7. Delayed Presentation of Tetralogy of Fallot with Isolated Cyanosis (PubMed)

Delayed Presentation of Tetralogy of Fallot with Isolated Cyanosis A pediatric patient with hypoxia or cyanosis can frighten even the most seasoned emergency providers. Patients with these symptoms require immediate evaluation and intervention to stabilize their condition. While the differential can be broad, specific attention must be paid to cardiopulmonary etiologies. Tetralogy of Fallot is the most common cyanotic congenital heart abnormality, and routine screening surprisingly misses

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2018 Case reports in pediatrics

8. On the dysfunctional hemoglobins and cyanosis connection: practical implications for the clinical detection and differentiation of methemoglobinemia and sulfhemoglobinemia (PubMed)

On the dysfunctional hemoglobins and cyanosis connection: practical implications for the clinical detection and differentiation of methemoglobinemia and sulfhemoglobinemia Methemoglobinemia and sulfhemoglobinemia are potentially life-threatening blood-related disorders characterized by similar symptoms and markedly distinct treatment procedures. In this paper, we investigate the causal relationship between these conditions and the onset of cyanosis, which is typically associated with a purple

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2018 Biomedical optics express

9. A Novel Brain Injury Biomarker Correlates with Cyanosis in Infants with Congenital Heart Disease. (PubMed)

A Novel Brain Injury Biomarker Correlates with Cyanosis in Infants with Congenital Heart Disease. Cyanotic heart lesions are a complex subset of congenital heart disease (CHD) in which patients are desaturated until surgical repair or palliation. We hypothesized that a direct relationship would exist between degree of desaturation and presence of systemic inflammation and brain injury in unrepaired patients less than 1 year of age. The pre-operative desaturation with augmented systemic

2018 Pediatric Cardiology

10. Long-Standing Cyanosis in Congenital Heart Disease Does not Cause Diffuse Myocardial Fibrosis. (PubMed)

Long-Standing Cyanosis in Congenital Heart Disease Does not Cause Diffuse Myocardial Fibrosis. The assumption of the presence of diffuse myocardial fibrosis in long-standing cyanotic congenital heart disease (CHD) inspired us to noninvasively determine the myocardial extracellular volume (ECV) using contrast CMR. T1 maps were measured pre and 10 min after the injection of 0.15 mmol/kg of gadolinium in 25 subjects. Seven patients with long-standing cyanotic CHD and no previous cardiac surgery (...) was calculated according to ΔR1myocardium/ΔR1blood * (1 - hematocrit). Cyanotic patients had significantly lower ECV percentage than the previous cyanotic patients (septum: 22 ± 2.7% vs 35 ± 4.6%, p = 0.002; LV wall: 22 ± 2.2% vs 30 ± 3.7%, p = 0.01, respectively). No significant differences were found between cyanotic patients and normal controls (septum: 22 ± 2.7% vs 24 ± 1.4%, p = 0.44; LV wall: 22 ± 2.2% vs 24 ± 2%, p = 0.57, respectively). Long-standing cyanosis in CHD without cardiac surgery does

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2017 Pediatric Cardiology

11. Familial clustering of congenital deafness, patent ductus arteriosus, Eisenmenger complex, and differential cyanosis: A case report. (PubMed)

Familial clustering of congenital deafness, patent ductus arteriosus, Eisenmenger complex, and differential cyanosis: A case report. Few studies had reported syndromes that include patent ductus arteriosus (PDA) with Eisenmenger syndrome and congenital deafness clustered in male siblings without facial, skeletal, or mental abnormalities.Two brothers, who were deaf and had PDA with Eisenmenger complex, were first seen at our Cardiology clinic at the ages of 25 and 41, respectively

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2017 Medicine

12. Unexpected episodes of cyanosis in late preterm and term neonates prompted admission to a neonatal care unit (PubMed)

Unexpected episodes of cyanosis in late preterm and term neonates prompted admission to a neonatal care unit We studied late preterm and term infants who were admitted to our neonatal care unit in a tertiary hospital for unexpected episodes of cyanosis that occurred during rooming-in for evaluation of their frequency, most frequent associated diseases, and documentation of the diagnostic clinical approach.We carried out a retrospective study of infants with a gestational age ≥35 weeks who were (...) admitted from the nursery with the diagnosis of cyanosis from January 2009 to December 2016. Exclusion criteria were the occurrence of acrocyanosis and the diagnosis of sudden unexpected postnatal collapse (SUPC).We studied 49 infants with a mean gestational age of 38 ± 2 weeks. The frequency of admission for cyanosis was 1.8/1000 live births and was similar (p = 0.167) in late preterm and term infants. The majority of episodes occurred during the first 24 h of life (57%). Only 16 infants (33%) were

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2017 Italian journal of pediatrics

13. Tuberous sclerosis presenting as neonatal cyanosis because of rhabdomyoma causing tricuspid valve obstruction needing a Blalock-Taussig shunt (PubMed)

Tuberous sclerosis presenting as neonatal cyanosis because of rhabdomyoma causing tricuspid valve obstruction needing a Blalock-Taussig shunt We report a newborn female baby who presented at 6 hours of age with cyanosis without any signs of respiratory distress. Cardiovascular and systemic examination was unremarkable apart from cyanosis (saturation 75%). An echocardiogram showed multiple echogenic and homogeneous masses in the interventricular septum, one of which was big and protruding

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2017 Journal of the Saudi Heart Association

14. Hemoglobin Kansas as a Rare Cause of Cyanosis: A Case Report and Review of the Literature (PubMed)

Hemoglobin Kansas as a Rare Cause of Cyanosis: A Case Report and Review of the Literature Hemoglobin (Hb) Kansas is an inherited Hb variant with a low oxygen affinity that is associated with low oxygen saturation on pulse oximetry (SpO2). It leads to asymptomatic cyanosis. Patients with Hb Kansas do not require any specific treatment and the prognosis is good. In patients with unexplained cyanosis, we should thus consider Hb variants, including Hb Kansas and avoid unnecessary investigations

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2017 Internal Medicine

15. Prolonged expiratory apnoea with cyanosis in Arnold Chiari II malformation (PubMed)

Prolonged expiratory apnoea with cyanosis in Arnold Chiari II malformation Apnoea associated with Arnold Chiari malformation is a known entity and can be obstructive or central. Differentiating between two types is vital to deciding management pathway and prognosticating disease process.

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2017 JRSM open

16. Benzocaine-Induced Cyanosis (PubMed)

Benzocaine-Induced Cyanosis 27257469 2016 06 03 2019 02 26 1937-5719 16 2016 Eplasty Eplasty Benzocaine-Induced Cyanosis. ic18 Jain Ankit A Department of Anesthesia, Rutgers New Jersey Medical School, Newark, NJ. Patel Anuradha A Department of Anesthesia, Rutgers New Jersey Medical School, Newark, NJ. Hoppe Ian C IC Department of Plastic Surgery, Rutgers New Jersey Medical School, Newark, NJ. eng Case Reports 2016 05 16 United States Eplasty 101316107 1937-5719 Benzocaine Cyanosis Desaturation

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2016 Eplasty

17. The Association Between Cyanosis and Thromboelastometry (ROTEM) in Children With Congenital Heart Defects: A Retrospective Cohort Study. (PubMed)

The Association Between Cyanosis and Thromboelastometry (ROTEM) in Children With Congenital Heart Defects: A Retrospective Cohort Study. Children with congenital heart defects (CHD) have quantitative and qualitative differences in coagulation compared with healthy children. Secondary to polycythemia and increased deformability of red blood cells, cyanosis may be an important confounding factor for altered whole-blood coagulation in this population with potential implications for interpreting (...) intraoperative thromboelastometry (TEM) for children with CHD undergoing major surgery. The primary aim of the study was to evaluate the association between cyanosis in children with CHD and measures of whole-blood coagulation determined using TEM (ROTEM [Tem International, GmbH, Munich, Germany]).In this retrospective cohort study, children who underwent congenital cardiac surgery in a 12-month period between April 2014 and 2015 were investigated. Children who were receiving antiplatelet or anticoagulant

2016 Anesthesia and Analgesia

18. Bier's anemic spots, cyanosis with urticaria-like eruption (BASCULE) syndrome: a new entity? (PubMed)

Bier's anemic spots, cyanosis with urticaria-like eruption (BASCULE) syndrome: a new entity? 27016170 2017 07 10 2017 10 06 1365-2133 175 1 2016 Jul The British journal of dermatology Br. J. Dermatol. Bier anaemic spots, cyanosis with urticaria-like eruption (BASCULE) syndrome: a new entity? 218-20 10.1111/bjd.14589 Bessis D D Department of Dermatology, Saint-Eloi Hospital, University Hospital of Montpellier, Montpellier, France. d-bessis@chu-montpellier.fr. University of Montpellier (...) Department of Dermatology, University Hospital of Grenoble, Grenoble, France. Pallure V V Department of Internal Medicine and Dermatology, Hospital Center of Perpignan, Perpignan, France. eng Case Reports Letter 2016 05 18 England Br J Dermatol 0004041 0007-0963 IM Br J Dermatol. 2016 Nov;175(5):1109-1110 27470123 Br J Dermatol. 2016 Nov;175(5):1110-1111 27479249 Adolescent Cyanosis complications Exanthema complications Female Humans Hypopigmentation complications Infant Male Pruritus etiology Syndrome

2016 British Journal of Dermatology

19. Primary neuroendocrine tumour of the right ventricle presenting with heart failure and cyanosis (PubMed)

Primary neuroendocrine tumour of the right ventricle presenting with heart failure and cyanosis A 68-year-old woman presented to the emergency department owing to exertional dyspnoea and bilateral leg oedema for 3 weeks. Her vital signs included the following: heart rate of 95 bpm, respiratory rate of 24 breaths/min, oxygen saturation of 73% on room air and a blood pressure of 184/108 mm Hg. Physical examination revealed tachypnoea with clear lungs to auscultation, elevated jugular veins (...) , cyanosis and bilateral pitting oedema. A chest X-ray demonstrated cardiomegaly without obvious pulmonary oedema. A CT of the chest was negative for pulmonary embolus; however, the scan did reveal a large right ventricular (RV) mass. An echocardiogram with bubble study confirmed a patent foramen ovale with significant right-to-left shunting and a large RV mass that significantly obstructed the pulmonary outflow tract. A cardiac biopsy revealed a low-grade neuroendocrine tumour. The patient underwent

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2016 BMJ case reports

20. Why so blue? A case of neonatal cyanosis due to congenital methaemoglobinaemia (HbM Iwate) (PubMed)

Why so blue? A case of neonatal cyanosis due to congenital methaemoglobinaemia (HbM Iwate) 27895078 2017 03 07 2018 12 07 1757-790X 2016 2016 Nov 28 BMJ case reports BMJ Case Rep Why so blue? A case of neonatal cyanosis due to congenital methaemoglobinaemia (HbM Iwate). bcr2016216805 10.1136/bcr-2016-216805 McGrath Jennifer S JS Newborn Care Unit, John Radcliffe Hospital, Oxford, UK. Datir Sonal S Newborn Care Unit, John Radcliffe Hospital, Oxford, UK. O'Brien Frances F Newborn Care Unit, John (...) Radcliffe Hospital, Oxford, UK. eng Case Reports Journal Article 2016 11 28 England BMJ Case Rep 101526291 1757-790X Congenital Methemoglobinemia IM Cyanosis congenital Humans Infant, Newborn Male Methemoglobinemia complications congenital Conflicts of Interest: None declared. 2016 11 30 6 0 2016 11 30 6 0 2017 3 8 6 0 epublish 27895078 bcr-2016-216805 10.1136/bcr-2016-216805 PMC5174777 Pediatr Ann. 2001 Oct;30(10):597-601 11641851 BMJ Case Rep. 2015 Mar 09;2015:null 25754164 BMJ Case Rep. 2015 Oct

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2016 BMJ case reports

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