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Cutaneous Candidiasis

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22. Microdilution in vitro Antifungal Susceptibility Patterns of Candida Species, From Mild Cutaneous to Bloodstream Infections Full Text available with Trip Pro

Microdilution in vitro Antifungal Susceptibility Patterns of Candida Species, From Mild Cutaneous to Bloodstream Infections Candida species, as opportunistic organisms, can cause various clinical manifestations, ranging from mild cutaneous infections to systemic candidiasis in otherwise healthy individuals. Remarkably, the incidence and mortality rates of candidemia have significantly increased worldwide, even after advances in medical interventions and the development of novel antifungal (...) drugs.Given the possible resistance to antifungal agents, susceptibility testing can be useful in defining the activity spectrum of antifungals and determining the appropriate treatment regime.The in vitro susceptibilities of molecularly identified Candida strains (n = 150) belonging to seven species recovered from clinical specimens, including vaginal, cutaneous, sputum, bronchoalveolar lavage (BAL), and blood samples, were determined for six antifungal drugs (amphotericin B, fluconazole, itraconazole

2016 Jundishapur journal of microbiology

23. Efficacy and safety of oral fluconazole in the treatment of patients with tinea corporis, cruris or pedis or cutaneous candidosis : a multicentre, open, noncomparative study. (Abstract)

Efficacy and safety of oral fluconazole in the treatment of patients with tinea corporis, cruris or pedis or cutaneous candidosis : a multicentre, open, noncomparative study. The efficacy, safety, required duration of treatment, and patient preference for oral fluconazole 150 mg/week in the treatment of 521 patients with cutaneous candidosis, tinea corporis, tinea cruris or tinea pedis were assessed in an open, multicentre, noncomparative trial. Patients received weekly doses of fluconazole (...) effective in the treatment of tinea corporis, tinea cruris, tinea pedis and cutaneous candidosis. Furthermore, there was a high patient preference for oral fluconazole over previous topical therapy.

2014 Clinical drug investigation Controlled trial quality: uncertain

24. Experimental In Vivo Models of Candidiasis Full Text available with Trip Pro

Experimental In Vivo Models of Candidiasis Candidiasis is a multifaceted fungal disease including mucosal-cutaneous, visceral, and disseminated infections caused by yeast species of the genus Candida. Candida infections are among the most common human mycoses. Candida species are the third to fourth most common isolates from bloodstream infections in neutropenic or immunocompromised hospitalized patients. The mucosal-cutaneous forms-particularly vaginal infections-have a high prevalence (...) . Vaginitis caused by Candida species is the second most common vaginal infection. Hence, candidiasis is a major subject for research, including experimental in vivo models to study pathogenesis, prevention, or therapy of the disease. The following review article will focus on various experimental in vivo models in different laboratory animals, such as mammals (mice, rats, rabbits), the fruit fly-Drosophila melanogaster, the larvae of the moth Galleria mellonella, or the free-living nematode

2018 Journal of Fungi

25. Isolation of <i>Candida auris</i> from invasive and non-invasive samples of a patient suffering from vascular disease, Italy, July 2019. Full Text available with Trip Pro

Isolation of Candida auris from invasive and non-invasive samples of a patient suffering from vascular disease, Italy, July 2019. We recently isolated Candida auris from a blood culture and cutaneous swabs of a patient in her mid-70s. Our routine phenotypic methods failed to identify the microorganism, but it was identified by molecular tests and MALDI-TOF MS analysis. Our report, the first from Italy, further underlines the geographically wide distribution of C. auris and the need

2019 Euro Surveillance

26. Role of mannose binding lectin in response to candida antigen immunotherapy of warts. (Abstract)

Role of mannose binding lectin in response to candida antigen immunotherapy of warts. Background: Warts is the commonest cutaneous manifestation of human papillomavirus (HPV) infection. Intralesional Candida antigen immunotherapy is used for wart treatment. Aim: To identify the role of mannose binding lectin (MBL) in susceptibility to HPV infection and to explore the relationship between MBL and response to intralesional Candida antigen immunotherapy of wart. Patients and methods: A case (...) -control study was enrolled with 96 participants; 48 wart cases and 48 healthy controls. MBL serum level assay baseline and after six settings of intralesional candida antigen injection was done by ELISA technique. MBL2 gene exon 1 codon 54 polymorphism was detected by using restriction fragment length polymorphism-polymerase chain reaction (RFLP-PCR). Results: A statistically significant difference in MBL serum level between wart cases and controls was found. An association between MBL2 exon1 codon 54

2019 Journal of Dermatological Treatment

27. Candida - oral

by Candida albicans . There are different types of oral candidiasis, including pseudomembranous candidiasis (often called oral thrush [which commonly affects neonates]), denture stomatitis (which commonly affects denture wearers), and chronic plaque-like candidiasis (which commonly occurs in men older than 30 years of age, and smokers). Comorbidities that increase the risk of candidal infections include diabetes mellitus, severe anaemia, and immunocompromise (such as due to chemotherapy, radiotherapy (...) Candida species that can cause infection in humans [ ; ] . Oral candidiasis is most commonly caused by Candida albicans , although it can occasionally be caused by other Candida species, such as C. glabrata , C. krusei , and C. tropicalis . Risk factors for oral candidiasis include: Extremes of ages — due to immature or weakened immunity. In addition, elderly people are more likely to have reduced salivary flow (xerostomia). Immunocompromise or systemic immunosuppression. This covers a wide spectrum

2017 NICE Clinical Knowledge Summaries

28. Candida - female genital

Candida - female genital Candida - female genital - NICE CKS Share Candida - female genital: Summary Vulvovaginal candidiasis (genital thrush) is a symptomatic inflammation of the vagina and/or vulva caused by a superficial fungal infection. Most cases are caused by a Candida yeast, although other yeasts are occasionally implicated. Vulvovaginal candidiasis infection can be classified as: Uncomplicated, which is sporadic or infrequent, mild to moderate, likely to be due to Candida albicans (...) (such as soaps and shower gels). General care of the vulval skin (for example moisturising with a simple emollient). Specialist advice should be sought, or referral arranged, if: The diagnosis is unclear. Symptoms do not improve following treatment. Non-albicans Candida species infection is present. Systemic symptoms occur. Have I got the right topic? Have I got the right topic? From age 12 years onwards (Female). This CKS topic covers the primary care management of vulvovaginal candidiasis (genital thrush

2017 NICE Clinical Knowledge Summaries

29. Candida - skin

are the core search terms that were used for Medline. candidiasis, cutaneous/, skin diseases, infectious/, intertrigo/, exp candida/, exp dermatomycoses/, skin.tw, candid$.tw, intertrigo.tw, thrush.tw, moniliasis.tw. Sources of guidelines Medline (with guideline filter) (occupational health practice) Sources of systematic reviews and meta-analyses : Systematic reviews Protocols Database of Abstracts of Reviews of Effects Medline (with systematic review filter) EMBASE (with systematic review filter) Sources (...) , 1391 . [ ] Primary Care Dermatology Society ( 2016a ) Candidal infection (syn. candidiasis; candidosis; moniliasis). Primary Care Dermatology Society. . [ ] Primary Care Dermatology Society ( 2016b ) Intertrigo. Primary Care Dermatology Society. . [ ]

2017 NICE Clinical Knowledge Summaries

30. Darier's disease can be complicated by generalised cutaneous candidiasis: a case-report. (Abstract)

01 28 England Br J Dermatol 0004041 0007-0963 0 Antifungal Agents IM Antifungal Agents therapeutic use Candida albicans Candidiasis, Cutaneous complications drug therapy Darier Disease complications Female Humans Middle Aged Recurrence 2014 8 22 6 0 2014 8 22 6 0 2015 12 19 6 0 ppublish 25142759 10.1111/bjd.13360 (...) Darier's disease can be complicated by generalised cutaneous candidiasis: a case-report. 25142759 2015 12 18 2015 03 17 1365-2133 172 3 2015 Mar The British journal of dermatology Br. J. Dermatol. Darier disease can be complicated by generalized cutaneous candidiasis: a case report. 837-9 10.1111/bjd.13360 Weiler L L Department of Dermatology, Lyon 1 University, Centre Hospitalier Lyon Sud, 69495, Pierre Bénite Cedex, France. Poulalhon N N Debarbieux S S Thomas L L eng Case Reports Letter 2015

2014 British Journal of Dermatology

31. Cyberlindnera jadinii (teleomorph Candida utilis) candidaemia in a patient with aplastic anaemia: a case report Full Text available with Trip Pro

Cyberlindnera jadinii (teleomorph Candida utilis) candidaemia in a patient with aplastic anaemia: a case report We present what is believed to be the first report of candidaemia caused by Cyberlindnera (Pichia) jadinii (teleomorph of Candida utilis) in a patient with an aplastic anaemia.The patient, a 21-year-old male, presented with hepatic cytolysis, cutaneous and pulmonary involvement, and septic shock. Cyberlindnera jadinii was identified by aerobic blood culture and MS. The patient (...) initially received multiple and combined antifungal therapy, but continued to have persistent skin lesions and fever. He was successfully treated by emergency haploidentical haematopoietic stem cell transplantation, combined with triple antifungal therapy and supportive care.Cyberlindnera jadinii, teleomorph of Candida utilis, which is not usually invasive, can lead to an opportunistic invasive infection in unhealthy adult patients. For treatment of the invasive candida infection, it is necessary

2018 JMM Case Reports

32. Immunodeficiencies in chronic muco-cutaneous candidosis Full Text available with Trip Pro

Immunodeficiencies in chronic muco-cutaneous candidosis 4336639 1972 06 30 2018 11 13 0019-2805 22 5 1972 May Immunology Immunology Immunodeficiencies in chronic muco-cutaneous candidosis. 775-87 Lehner T T Wilton J M JM Ivanyi L L eng Journal Article England Immunology 0374672 0019-2805 0 Antigens 0 Immunoglobulin A 0 Immunoglobulin G 0 Immunoglobulins 9007-49-2 DNA IM Animals Antibody Formation Antigens Candida albicans immunology Candidiasis, Cutaneous immunology Cell Migration Inhibition

1972 Immunology

33. Candidiasis, Cutaneous (Overview)

: May 22, 2018 Author: Noah S Scheinfeld, JD, MD, FAAD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Cutaneous Candidiasis Overview Background Cutaneous candidiasis and other forms of candidosis are infections caused by the yeast Candida albicans or other Candida species. Yeasts are unicellular fungi that typically reproduce by budding, a process that entails a progeny pinching off of the mother cell. C albicans , the principal infectious agent in human (...) , Fernández-Castillo R, González-Jiménez E, Cantero-Hinojosa J, Lardón-Fernández M. [Generalized cutaneous candidiasis in newborn at term]. Biomedica . 2012 Jun. 32(2):170-3. . Ramirez De Knott HM, McCormick TS, Do SO, et al. Cutaneous hypersensitivity to Candida albicans in idiopathic vulvodynia. Contact Dermatitis . 2005 Oct. 53(4):214-8. . Gibney MD, Siegfried EC. Cutaneous congenital candidiasis: a case report. Pediatr Dermatol . 1995 Dec. 12(4):359-63. . Raval DS, Barton LL, Hansen RC, Kling PJ

2014 eMedicine.com

34. Candidiasis, Cutaneous (Treatment)

at term]. Biomedica . 2012 Jun. 32(2):170-3. . Ramirez De Knott HM, McCormick TS, Do SO, et al. Cutaneous hypersensitivity to Candida albicans in idiopathic vulvodynia. Contact Dermatitis . 2005 Oct. 53(4):214-8. . Gibney MD, Siegfried EC. Cutaneous congenital candidiasis: a case report. Pediatr Dermatol . 1995 Dec. 12(4):359-63. . Raval DS, Barton LL, Hansen RC, Kling PJ. Congenital cutaneous candidiasis: case report and review. Pediatr Dermatol . 1995 Dec. 12(4):355-8. . Hoppe JE. Treatment (...) Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America. Clin Infect Dis . 2016 Feb 15. 62 (4):409-17. . Del Rosso JQ, Kircik LH. Optimizing topical antifungal therapy for superficial cutaneous fungal infections: focus on topical naftifine for cutaneous dermatophytosis. J Drugs Dermatol . 2013 Nov 1. 12(11):s165-71. . Macherla C, Sanchez DA, Ahmadi MS, et al. Nitric oxide releasing nanoparticles for treatment of Candida albicans burn infections

2014 eMedicine.com

35. Candidiasis, Cutaneous (Follow-up)

at term]. Biomedica . 2012 Jun. 32(2):170-3. . Ramirez De Knott HM, McCormick TS, Do SO, et al. Cutaneous hypersensitivity to Candida albicans in idiopathic vulvodynia. Contact Dermatitis . 2005 Oct. 53(4):214-8. . Gibney MD, Siegfried EC. Cutaneous congenital candidiasis: a case report. Pediatr Dermatol . 1995 Dec. 12(4):359-63. . Raval DS, Barton LL, Hansen RC, Kling PJ. Congenital cutaneous candidiasis: case report and review. Pediatr Dermatol . 1995 Dec. 12(4):355-8. . Hoppe JE. Treatment (...) Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America. Clin Infect Dis . 2016 Feb 15. 62 (4):409-17. . Del Rosso JQ, Kircik LH. Optimizing topical antifungal therapy for superficial cutaneous fungal infections: focus on topical naftifine for cutaneous dermatophytosis. J Drugs Dermatol . 2013 Nov 1. 12(11):s165-71. . Macherla C, Sanchez DA, Ahmadi MS, et al. Nitric oxide releasing nanoparticles for treatment of Candida albicans burn infections

2014 eMedicine.com

36. Candidiasis, Cutaneous (Diagnosis)

: May 22, 2018 Author: Noah S Scheinfeld, JD, MD, FAAD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Cutaneous Candidiasis Overview Background Cutaneous candidiasis and other forms of candidosis are infections caused by the yeast Candida albicans or other Candida species. Yeasts are unicellular fungi that typically reproduce by budding, a process that entails a progeny pinching off of the mother cell. C albicans , the principal infectious agent in human (...) , Fernández-Castillo R, González-Jiménez E, Cantero-Hinojosa J, Lardón-Fernández M. [Generalized cutaneous candidiasis in newborn at term]. Biomedica . 2012 Jun. 32(2):170-3. . Ramirez De Knott HM, McCormick TS, Do SO, et al. Cutaneous hypersensitivity to Candida albicans in idiopathic vulvodynia. Contact Dermatitis . 2005 Oct. 53(4):214-8. . Gibney MD, Siegfried EC. Cutaneous congenital candidiasis: a case report. Pediatr Dermatol . 1995 Dec. 12(4):359-63. . Raval DS, Barton LL, Hansen RC, Kling PJ

2014 eMedicine.com

37. Candidiasis

of the genus Candida; usually a superficial infection of the moist areas of the body and is generally caused by Candida albicans; includes chronic mucocutaneous candidiasis, cutaneous candidiasis, oral candidiasis (thrush), and monilial vaginitis. Concepts Disease or Syndrome ( T047 ) MSH ICD9 112.9, 112 ICD10 , SnomedCT 187005005 , 187024008 , 187478002 , 154403005 , 370520002 , 78048006 English Candidiases , Candidiasis , Moniliases , Moniliasis , CANDIDIASIS , MONILIASIS , Candidiasis, unspecified , [X (...) ]Candidiasis, unspecified , candidiasis , candidiasis (diagnosis) , Candida infections , Candidiasis site NOS , candidosis , Candidiasis [Disease/Finding] , candidal infection , candidal infections , monilial infection , thrush , candida infections , candidiases , candida infection , muguet , monilia infection , Candidiasis NOS (disorder) , [X]Candidiasis, unspecified (disorder) , Candida NOS , Monilial infection , Moniliasis monilia , Moniliasis NOS , Candidiasis of unspecified site , Monilia NOS

2018 FP Notebook

38. Cutaneous Candidiasis

, Cutaneous , Cutaneous Moniliasis , Skin Candidiasis , Cutaneous Candidiasis , cutaneous candidiasis (diagnosis) , cutaneous candidiasis , Candida rash , Skin candida NOS , Candidiasis of skin NOS , Cutaneous moniliasis , Moniliasis cutaneous , Monilia of skin NOS , Monilial rash , Moniliasis skin , Thrush of skin NOS , Cutaneous candidiasis , Candidiasis, Cutaneous [Disease/Finding] , candida skin , skin thrush , skin candida , rash candida , candidiasis cutaneous , candida infections skin , candida (...) skin infection , cutaneous moniliasis , candida rash , candidiasis skin , Candida of skin , Skin candida , Candidiasis of skin , Candidosis of skin , Candidiasis of skin (disorder) , candidiasis; skin , skin; candidiasis Italian Candida della cute , Eruzione da candida , Candida cutanea NAS , Candidiasi della pelle , Candidiasi cutanea non specificata , Esantema da Candida , Candida della cute NAS , Candidiasi della cute , Candidiasi della cute NAS , Moniliasi cutanea , Candidosi cutanea Dutch

2015 FP Notebook

39. Efficacy and Safety in 1% Clotrimazole Powder, Adjuvant Therapy in Patients with Superficial Fungal Cutaneous Infection in Intertriginous Areas. (Abstract)

were significantly higher than the control group, as observed within four weeks (p = 0.01), especially for dermatophyte infection (p = 0.039). Two cases had recurrent candidiasis in the control group. In both groups, relapse up to 24 weeks were not statistically different. Additionally, there was no difference in patients’ satisfaction towards convenience of drug application.Using of the 1% CP could be suggested as an adjuvant therapy and possibly preventive agent for superficial fungal cutaneous (...) Efficacy and Safety in 1% Clotrimazole Powder, Adjuvant Therapy in Patients with Superficial Fungal Cutaneous Infection in Intertriginous Areas. Superficial fungal cutaneous infection is commonly found in intertriginous area.To assess 1% clotrimazole powder (1% CP) efficacy for adjuvant treatment of superficial fungal cutaneous infection in intertriginous areas.The study performed as an open-label, randomized, comparative study for evaluating the effects of 1% clotrimazole cream (1% CC) with 1

2018 Journal of the Medical Association of Thailand = Chotmaihet thangphaet Controlled trial quality: uncertain

40. Development of the cutaneous microbiome in the preterm infant: A prospective longitudinal study. Full Text available with Trip Pro

Development of the cutaneous microbiome in the preterm infant: A prospective longitudinal study. Neonatal sepsis in preterm infants is often due to organisms that colonize the skin including Staphylococcus spp. and Candida spp. Development and maturation of the skin microbiome in the neonatal period, especially in preterm infants, may be critical in preventing colonization with pathogens and subsequent progression to neonatal sepsis. Development of the skin microbiome in preterm infants or its (...) and function, is associated with the development of the preterm cutaneous microbiome. Understanding the maturation of a healthy skin microbiome, prevention of pathogen colonization and its role in the development of immunity will be pivotal in the development of novel interventions to prevent infections in critically ill preterm infants.

2017 PLoS ONE

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