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Cutaneous Candidiasis

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21. Cutaneous Candidiasis

Cutaneous Candidiasis Cutaneous Candidiasis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Cutaneous Candidiasis Cutaneous (...) Candidiasis Aka: Cutaneous Candidiasis From Related Chapters II. Risk Factors Systemic antibiotics Ill-fitting dentures Pregnancy Elderly III. Exam: Distribution Perioral dermatitis Cheilitis IV. Differential Diagnosis Drug allergy (HSV) (e.g. ) Dermatophyte See Differential Diagnosis for V. Management Cutaneous Candidiasis Topical anti-fungal Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Cutaneous Candidiasis." Click on the image

2015 FP Notebook

22. Proof of Mechanism Study of GSK2330811 in Diffuse Cutaneous Systemic Sclerosis

Proof of Mechanism Study of GSK2330811 in Diffuse Cutaneous Systemic Sclerosis Proof of Mechanism Study of GSK2330811 in Diffuse Cutaneous Systemic Sclerosis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Proof of Mechanism Study of GSK2330811 in Diffuse Cutaneous Systemic Sclerosis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03041025 Recruitment Status : Recruiting First Posted : February 2, 2017 Last Update Posted

2017 Clinical Trials

23. Experimental murine candidiasis: cell-mediated immunity after cutaneous challenge. (PubMed)

Experimental murine candidiasis: cell-mediated immunity after cutaneous challenge. Attempts were made to isolate an antigen(s) from Candida albicans suitable for detecting hypersensitivity in a murine model of candidiasis. Using footpad reactivity in cutaneously infected animals as the assay, comparisons were made of two commercial extracts and cell wall and cytoplasmic preparations made in the laboratory. An extract of the cell wall, a glycoprotein (GP) removed with ethylenediamine

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1978 Infection and immunity

24. Experimental murine candidiasis: pathological and immune responses to cutaneous inoculation with Candida albicans. (PubMed)

Experimental murine candidiasis: pathological and immune responses to cutaneous inoculation with Candida albicans. Cutaneous infection of mice with Candida albicans elicited a predominantly acute inflammatory response, stimulated the production of precipitating antibodies, and conferred protection against subsequent intravenous challenge with the same organism. The acute inflammatory skin reaction seen after cutaneous infection suggested a predominantly humoral response to Candida. Animals (...) infected cutaneously a second time with viable C. albicans developed larger skin lesions than animals infected only once, and the twice-infected animals were more resistant to an intravenous challenge as well. The cutaneous inoculation of mice with heat-killed C. albicans was less effective in stimulating antibody production, in eliciting the inflammatory response, and in inducing a protective response demonstrable by intravenous challenge with viable Candida. This model of experimental candidiasis

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1978 Infection and immunity

25. Familial chronic muco-cutaneous candidiasis. (PubMed)

Familial chronic muco-cutaneous candidiasis. 4562433 1972 12 26 2018 11 13 0022-2593 9 3 1972 Sep Journal of medical genetics J. Med. Genet. Familial chronic muco-cutaneous candidiasis. 302-10 Wells R S RS Higgs J M JM Macdonald A A Valdimarsson H H Holt P J PJ eng Journal Article England J Med Genet 2985087R 0022-2593 11103-57-4 Vitamin A E1UOL152H7 Iron KV2JZ1BI6Z Pyridoxine IM Candida isolation & purification Candida albicans isolation & purification Candidiasis, Cutaneous complications (...) Candidiasis, Oral blood complications drug therapy etiology genetics immunology Chronic Disease Endocrine System Diseases complications Female Genes, Recessive Humans Iron blood Male Pedigree Pyridoxine blood Skin Tests Syndrome Vitamin A blood 1972 9 1 1972 9 1 0 1 1972 9 1 0 0 ppublish 4562433 PMC1469124 Lancet. 1970 Jun 13;1(7659):1259-61 4192497 Vitam Horm. 1964;22:591-607 14284121 J Lab Clin Med. 1953 Sep;42(3):335-57 13085024 Am J Med. 1968 Jun;44(6):979-89 4172913 Arch Dermatol. 1962 Feb;85:233-57

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1972 Journal of Medical Genetics

26. Topical treatment of inflammatory dermatoses and cutaneous candidiasis with a new cortico-steroid -antibiotic combination: halcinonide-neomycin-amphotericin. (PubMed)

Topical treatment of inflammatory dermatoses and cutaneous candidiasis with a new cortico-steroid -antibiotic combination: halcinonide-neomycin-amphotericin. 326284 1977 08 12 2018 11 30 0007-0947 31 4 1977 Apr The British journal of clinical practice Br J Clin Pract Topical treatment of inflammatory dermatoses and cutaneous candidiasis with a new cortico-steroid -antibiotic combination: halcinonide-neomycin-amphotericin. 33-5, 39 Reyes-Javier P P eng Clinical Trial Journal Article Randomized (...) Controlled Trial England Br J Clin Pract 0372546 0007-0947 0 Anti-Inflammatory Agents 0 Drug Combinations 0 Glucocorticoids 0 Pregnenediones 7XU7A7DROE Amphotericin B I16QD7X297 Neomycin IM Administration, Topical Adolescent Adult Aged Amphotericin B therapeutic use Anti-Inflammatory Agents therapeutic use Candidiasis, Cutaneous drug therapy Child Child, Preschool Clinical Trials as Topic Dermatitis drug therapy Drug Combinations Female Glucocorticoids Humans Male Middle Aged Neomycin therapeutic use

1977 The British journal of clinical practice Controlled trial quality: uncertain

27. Evaluation of a topical steroid antibiotic combination (halcinonide-neomycin-amphotericin) in the treatment of cutaneous candidiasis and inflammatory dermatoses. (PubMed)

Evaluation of a topical steroid antibiotic combination (halcinonide-neomycin-amphotericin) in the treatment of cutaneous candidiasis and inflammatory dermatoses. Halcinonide-neomycin-amphotericin (HNA) cream was evaluated in the treatment of cutaneous candidiasis and inflammatory dermatoses. The anti-candidal properties of HNA were assessed in a parallel comparison with iodochlorhydroxyquin-hydrocortisone (I-HC) as the control drug. The overall therapeutic response with HNA was excellent in 38

1979 Current medical research and opinion Controlled trial quality: uncertain

28. Cutaneous candidiasis: treatment with miconazole nitrate. (PubMed)

Cutaneous candidiasis: treatment with miconazole nitrate. In a well-controlled, double-blind, randomized study, 30 patients with cutaneous candidiasis were treated with a 2% miconazole nitrate lotion or its placebo control. By the 14th day, 13 of the 15 patients [87%] treated with miconazole nitrate achieved clinical and mycologic cures. Only a single patient treated with the placebo lotion would be classified as a therapeutic cure. In a second portion of the study those patients judged

1977 Cutis; cutaneous medicine for the practitioner Controlled trial quality: uncertain

29. Novel lecithin-integrated liquid crystalline nanogels for enhanced cutaneous targeting of terconazole: development, in vitro and in vivo studies (PubMed)

Novel lecithin-integrated liquid crystalline nanogels for enhanced cutaneous targeting of terconazole: development, in vitro and in vivo studies Terconazole (Tr) is the first marketed, most active triazole for vaginal candidiasis. Owing to poor skin permeation and challenging physicochemical properties, Tr was not employed for the treatment of cutaneous candidiasis. This is the first study to investigate the relevance of novel lecithin-integrated liquid crystalline nano-organogels (LCGs (...) ) to improve physicochemical characteristics of Tr in order to enable its dermal application in skin candidiasis. Ternary phase diagram was constructed using lecithin/capryol 90/water to identify the region of liquid crystalline organogel. The selected organogel possessed promising physicochemical characteristics based on particle size, rheological behavior, pH, loading efficiency, and in vitro antifungal activity. Microstructure of the selected organogel was confirmed by polarized light microscopy

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2016 International journal of nanomedicine

30. A retrospective study of cutaneous fungal infections in patients referred to Imam Reza Hospital of Mashhad, Iran during 2000-2011 (PubMed)

suspected of superficial and cutaneous mycosis, referred to the Medical Mycology Laboratory of Imam Reza Hospital of Mashhad, Iran, were recruited during March 2000-2011 and were examined in terms of fungal infections.Of 8694 suspected patients, 3804 (43.75%) cases suffered from superficial and cutaneous mycosis. In total, 1936 (50.9%) patients were male, and 1868 (49.1%) were female. Malassezia infections (58.1%), dermatophytosis (33.1%), cutaneous candidiasis (6.8%), aspergillosis (1.6 (...) A retrospective study of cutaneous fungal infections in patients referred to Imam Reza Hospital of Mashhad, Iran during 2000-2011 Detection of agents responsible for cutaneous mycosis may be effective in the prevention of fungal infections from environmental and animal sources. With this background in mind, in this study, we aimed to identify the distribution of cutaneous mycotic infections in patients referred to Imam Reza Hospital of Mashhad, Iran during 2000- 2011.In total, 8694 patients

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2016 Current Medical Mycology

31. Hydroxychavicol: A phytochemical targeting cutaneous fungal infections (PubMed)

potential and time-kill curve results revealed concentration-dependent killing. It also inhibited the growth of biofilm generated by Trichophyton mentagrophytes and Candida parapsilosis and reduced the preformed biofilms. Hydroxychavicol was highly effective in the treatment, and mycological eradication of an experimentally induced topical infection model of dermatophytosis (tinea corporis) and cutaneous candidiasis in guinea pigs, respectively. The mode of action of hydroxychavicol appears to originate (...) Hydroxychavicol: A phytochemical targeting cutaneous fungal infections The present study was designed to investigate the potency of hydroxychavicol on selected cutaneous human pathogenic fungi by the use of in vitro and in vivo assays and mechanistic characterization along with toxicological effects. Hydroxychavicol consistently displayed a fungicidal effect against all fungal species tested. Inoculum concentrations over the range of 104 to 107 CFU/ml did not significantly alter its antifungal

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2016 Scientific reports

32. Microdilution in vitro Antifungal Susceptibility Patterns of Candida Species, From Mild Cutaneous to Bloodstream Infections (PubMed)

Microdilution in vitro Antifungal Susceptibility Patterns of Candida Species, From Mild Cutaneous to Bloodstream Infections Candida species, as opportunistic organisms, can cause various clinical manifestations, ranging from mild cutaneous infections to systemic candidiasis in otherwise healthy individuals. Remarkably, the incidence and mortality rates of candidemia have significantly increased worldwide, even after advances in medical interventions and the development of novel antifungal (...) drugs.Given the possible resistance to antifungal agents, susceptibility testing can be useful in defining the activity spectrum of antifungals and determining the appropriate treatment regime.The in vitro susceptibilities of molecularly identified Candida strains (n = 150) belonging to seven species recovered from clinical specimens, including vaginal, cutaneous, sputum, bronchoalveolar lavage (BAL), and blood samples, were determined for six antifungal drugs (amphotericin B, fluconazole, itraconazole

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2016 Jundishapur journal of microbiology

33. Candidiasis, Chronic Mucocutaneous (Overview)

Candidiasis, Chronic Mucocutaneous (Overview) Chronic Mucocutaneous Candidiasis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA5MTkyOC1vdmVydmlldw== processing (...) > Chronic Mucocutaneous Candidiasis Updated: Apr 17, 2017 Author: Blanca Anais Estupiñan; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Chronic Mucocutaneous Candidiasis Overview Background Chronic mucocutaneous candidiasis (CMC) refers to a heterogeneous group of disorders characterized by recurrent or persistent superficial infections of the skin, mucous membranes, and nails with Candida organisms, usually Candida albicans. These disorders are confined

2014 eMedicine.com

34. Candidiasis (Overview)

Cutaneous candidiasis - Using a wet mount, scrapings or smears obtained from skin or nails can be examined under the microscope; potassium hydroxide smears are also useful Genitourinary candidiasis - A urinalysis should be performed; evidence of white blood cells (WBCs), red blood cells (RBCs), protein, and yeast cells is common; urine fungal cultures are useful Gastrointestinal candidiasis - Endoscopy with or without biopsy See for more detail. Management See the list below: Cutaneous candidiasis (...) - Most localized cutaneous candidiasis infections can be treated with any number of topical antifungal agents (eg, clotrimazole, econazole, ciclopirox, miconazole, ketoconazole, nystatin) Chronic mucocutaneous candidiasis - This condition is generally treated with oral azoles Oropharyngeal candidiasis - This can be treated with either topical antifungal agents or systemic oral azoles Esophageal candidiasis - Treatment requires systemic therapy with fluconazole VVC - Topical antifungal agents or oral

2014 eMedicine.com

35. Candidiasis, Chronic Mucocutaneous (Diagnosis)

Candidiasis, Chronic Mucocutaneous (Diagnosis) Chronic Mucocutaneous Candidiasis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA5MTkyOC1vdmVydmlldw== processing (...) > Chronic Mucocutaneous Candidiasis Updated: Apr 17, 2017 Author: Blanca Anais Estupiñan; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Chronic Mucocutaneous Candidiasis Overview Background Chronic mucocutaneous candidiasis (CMC) refers to a heterogeneous group of disorders characterized by recurrent or persistent superficial infections of the skin, mucous membranes, and nails with Candida organisms, usually Candida albicans. These disorders are confined

2014 eMedicine.com

36. Candidiasis (Diagnosis)

Cutaneous candidiasis - Using a wet mount, scrapings or smears obtained from skin or nails can be examined under the microscope; potassium hydroxide smears are also useful Genitourinary candidiasis - A urinalysis should be performed; evidence of white blood cells (WBCs), red blood cells (RBCs), protein, and yeast cells is common; urine fungal cultures are useful Gastrointestinal candidiasis - Endoscopy with or without biopsy See for more detail. Management See the list below: Cutaneous candidiasis (...) - Most localized cutaneous candidiasis infections can be treated with any number of topical antifungal agents (eg, clotrimazole, econazole, ciclopirox, miconazole, ketoconazole, nystatin) Chronic mucocutaneous candidiasis - This condition is generally treated with oral azoles Oropharyngeal candidiasis - This can be treated with either topical antifungal agents or systemic oral azoles Esophageal candidiasis - Treatment requires systemic therapy with fluconazole VVC - Topical antifungal agents or oral

2014 eMedicine.com

37. Candidiasis (Treatment)

treatments. Ketoconazole tablets were also withdrawn from the market in the European Union in July 2013. [ , ] The therapeutic options available for the management of invasive candidiasis and candidemia have continued to increase with the addition of newer echinocandins [ , ] and triazoles. Cutaneous candidiasis Most localized cutaneous candidiasis infections may be treated with any number of topical antifungal agents (eg, clotrimazole, econazole, ciclopirox, miconazole, ketoconazole, nystatin (...) Candidiasis (Treatment) Candidiasis Treatment & Management: Medical Care, Surgical Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjEzODUzLXRyZWF0bWVudA== processing > Candidiasis Treatment

2014 eMedicine.com

38. Candidiasis (Overview)

are immunocompromised may suffer from candidal esophagitis as well as thrush. Genitals Vaginal yeast infections affect nearly 75% of women. Male partners may develop balanitis or balanoposthitis. Individuals with chronic indwelling catheters are also predisposed to recurrent candidal infections. Systemic Candida organisms can cause severe systemic infections in immunocompromised patients, compared with benign cutaneous or localized infections in immunocompetent patients. Reports of systemic candidiasis are common (...) Candidiasis (Overview) Pediatric Candidiasis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvOTYyMzAwLW92ZXJ2aWV3 processing > Pediatric Candidiasis Updated: Dec 17, 2018

2014 eMedicine Pediatrics

39. Candidiasis (Diagnosis)

are immunocompromised may suffer from candidal esophagitis as well as thrush. Genitals Vaginal yeast infections affect nearly 75% of women. Male partners may develop balanitis or balanoposthitis. Individuals with chronic indwelling catheters are also predisposed to recurrent candidal infections. Systemic Candida organisms can cause severe systemic infections in immunocompromised patients, compared with benign cutaneous or localized infections in immunocompetent patients. Reports of systemic candidiasis are common (...) Candidiasis (Diagnosis) Pediatric Candidiasis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvOTYyMzAwLW92ZXJ2aWV3 processing > Pediatric Candidiasis Updated: Dec 17, 2018

2014 eMedicine Pediatrics

40. Candidiasis (Follow-up)

=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvNzgxMjE1LWZvbGxvd3Vw processing > Candidiasis in Emergency Medicine Follow-up Updated: Oct 12, 2017 Author: Sukhveer (Sukhi) Bains, MD, MA; Chief Editor: Jeter (Jay) Pritchard Taylor, III, MD Share Email Print Feedback Close Sections Sections Candidiasis in Emergency Medicine Follow-up Further Outpatient Care Uncomplicated vaginal and cutaneous candidiasis: When treated in the ED and discharged with medication, patients should be instructed to see their primary physician if symptoms persist or worsen (...) Candidiasis (Follow-up) Candidiasis in Emergency Medicine Follow-up: Further Outpatient Care, Further Inpatient Care, Inpatient & Outpatient Medications Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache

2014 eMedicine Emergency Medicine

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