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Cutaneous Candidiasis

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1. Infection and tissue repair of experimental cutaneous candidiasis in diabetic mice. (PubMed)

Infection and tissue repair of experimental cutaneous candidiasis in diabetic mice. Diabetic patients seem to be predisposed to cutaneous candidiasis. In this study, we evaluated the interference of diabetic conditions in alloxan-induced diabetic mice in relation to the development of C. albicans infection, density of M1 and M2 macrophages, distribution of collagen type I and III and anti-inflamamatory cytokines involved in tissue repair.The mice were treated with intravenous alloxan, and all (...) was increased by interference of IL-13 and transforming growth factor-β cytokines.These findings highlight some important changes in diabetic animal responses to C. albicans infection that may be important to the pathophysiological processes underpinning cutaneous candidiasis in diabetic patients.

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2017 Journal of Medical Microbiology

2. Congenital Cutaneous Candidiasis: Prompt Systemic Treatment Is Associated With Improved Outcomes in Neonates. (PubMed)

Congenital Cutaneous Candidiasis: Prompt Systemic Treatment Is Associated With Improved Outcomes in Neonates. Congenital cutaneous candidiasis (CCC) is a challenging diagnosis due to various rash presentations. Inadequate early treatment is associated with high rates of dissemination and death. The effects of early diagnosis, dermatologic presentation, and antifungal treatment on outcomes are lacking.CCC cases were reviewed from 2 academic neonatal intensive care units (NICUs) from 2004 to 2015

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2017 Clinical Infectious Diseases

3. Congenital cutaneous candidiasis (PubMed)

Congenital cutaneous candidiasis 27516110 2017 02 23 2018 11 13 1757-790X 2016 2016 Aug 11 BMJ case reports BMJ Case Rep Congenital cutaneous candidiasis. 10.1136/bcr-2016-216037 bcr2016216037 Chen Kai-Lung KL Department of Dermatology, National Taiwan University Hospital, Taipei City, Taiwan. Chien Mu-Ming MM http://orcid.org/0000-0002-0988-4012 Department of Pediatrics, National Taiwan University Children Hospital, Taipei City, Taiwan. Chen Chien-Yi CY Department of Pediatrics, National (...) Taiwan University Children Hospital, Taipei City, Taiwan. Chiu Hsien-Ching HC Department of Dermatology, National Taiwan University Hospital, Taipei City, Taiwan. eng Case Reports Journal Article 2016 08 11 England BMJ Case Rep 101526291 1757-790X IM Adult Candidiasis transmission Candidiasis, Cutaneous congenital Female Humans Infant, Newborn Infectious Disease Transmission, Vertical Male Pregnancy Pregnancy Complications, Infectious microbiology Vaginal Diseases microbiology 2016 8 13 6 0 2016 8 16

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2016 BMJ case reports

4. Cutaneous Candidiasis

Cutaneous Candidiasis Cutaneous Candidiasis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Cutaneous Candidiasis Cutaneous (...) Candidiasis Aka: Cutaneous Candidiasis From Related Chapters II. Risk Factors Systemic antibiotics Ill-fitting dentures Pregnancy Elderly III. Exam: Distribution Perioral dermatitis Cheilitis IV. Differential Diagnosis Drug allergy (HSV) (e.g. ) Dermatophyte See Differential Diagnosis for V. Management Cutaneous Candidiasis Topical anti-fungal Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Cutaneous Candidiasis." Click on the image

2018 FP Notebook

5. Effect of long-term exposure of mice to 900 MHz GSM radiation on experimental cutaneous candidiasis (PubMed)

Effect of long-term exposure of mice to 900 MHz GSM radiation on experimental cutaneous candidiasis Mobile phones communicate with base stations using 900 MHz microwaves. The current study was aimed to survey the effects of long-term 900 MHz microwave exposure of mice on experimentally induced cutaneous candidiasis. Forty inbred, male, BALB/c mice were randomly divided into four groups. Cutaneous lesions with Candida albicans were experimentally induced on the lateral-back skin of the 20 mice

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2016 Saudi journal of biological sciences

6. Immunological and histopathological characterization of cutaneous candidiasis. (PubMed)

Immunological and histopathological characterization of cutaneous candidiasis. Chronic mucocutaneous candidiasis constitutes a heterogeneous group of syndromes, characterized by non-invasive infection of the skin, nails and mucosal membranes by the fungus Candida spp. Although symptoms are heterogeneous, in all cases there is a reduction in protective cytokines, favouring the development of disease. The normal role of cytokines in skin lesions is not well understood. The present study aimed (...) . Anti-inflammatory cytokines (IL-13, IL-4, IL-10 and transforming growth factor-β) were detected on day 4 post-infection, and prevented exacerbation of inflammation and participated in healing of lesions. Thus, a balance between pro- and anti-inflammatory cytokines was fundamental for the resolution of infection. Importantly, these findings broaden our understanding of the immune mechanisms involved in chronic cutaneous candidiasis.

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2015 Journal of Medical Microbiology

7. Primary immunodeficiency update: Part II. Syndromes associated with mucocutaneous candidiasis and noninfectious cutaneous manifestations. (PubMed)

Primary immunodeficiency update: Part II. Syndromes associated with mucocutaneous candidiasis and noninfectious cutaneous manifestations. Several primary immunodeficiencies (PIDs) have recently been described that confer an elevated risk of fungal infections and noninfectious cutaneous manifestations. In addition, immunologic advances have provided new insights into our understanding of the pathophysiology of fungal infections in established PIDs. We reviewed PIDs that present (...) with an eczematous dermatitis in part I. In part II of this continuing medical education article we discuss updates on PIDs associated with fungal infections, their biologic basis in PIDs, and noninfectious cutaneous manifestations. Published by Elsevier Inc.

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2015 Journal of American Academy of Dermatology

9. Paediatric Oropharyngeal and Cutaneous Candidiasis with Special Reference to Candida dubliniensis. (PubMed)

Paediatric Oropharyngeal and Cutaneous Candidiasis with Special Reference to Candida dubliniensis. Mucocutaneous and cutaneous candidiasis, though common in children, is often under-reported. The prevalence of Candida dubliniensis in causing these infections in this age group is also largely unknown. A prospective epidemiological cross-sectional study for candidiasis was performed in paediatric patients clinically suspected of candidiasis with oropharyngeal lesions (75 patients), cutaneous (...) lesions (18 patients) and lesions at both sites (2 patients). Candida species were identified by conventional tests. For C. dubliniensis, chlamydospore production, growth on tobacco agar and growth at 45 °C were performed. Nine isolates were confirmed at a reference centre. The rates of candidiasis were 77.3 % (58 out of 75 patients clinically suspected of candidiasis) and 83.3 % (15/18) in oropharyngeal and cutaneous lesions respectively, and 1 of the 2 children with lesions at both sites

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2014 Journal of Medical Microbiology

10. Darier's disease can be complicated by generalised cutaneous candidiasis: a case-report. (PubMed)

Darier's disease can be complicated by generalised cutaneous candidiasis: a case-report. 25142759 2015 12 18 2015 03 17 1365-2133 172 3 2015 Mar The British journal of dermatology Br. J. Dermatol. Darier disease can be complicated by generalized cutaneous candidiasis: a case report. 837-9 10.1111/bjd.13360 Weiler L L Department of Dermatology, Lyon 1 University, Centre Hospitalier Lyon Sud, 69495, Pierre Bénite Cedex, France. Poulalhon N N Debarbieux S S Thomas L L eng Case Reports Letter 2015 (...) 01 28 England Br J Dermatol 0004041 0007-0963 0 Antifungal Agents IM Antifungal Agents therapeutic use Candida albicans Candidiasis, Cutaneous complications drug therapy Darier Disease complications Female Humans Middle Aged Recurrence 2014 8 22 6 0 2014 8 22 6 0 2015 12 19 6 0 ppublish 25142759 10.1111/bjd.13360

2014 British Journal of Dermatology

11. Experimental In Vivo Models of Candidiasis (PubMed)

Experimental In Vivo Models of Candidiasis Candidiasis is a multifaceted fungal disease including mucosal-cutaneous, visceral, and disseminated infections caused by yeast species of the genus Candida. Candida infections are among the most common human mycoses. Candida species are the third to fourth most common isolates from bloodstream infections in neutropenic or immunocompromised hospitalized patients. The mucosal-cutaneous forms-particularly vaginal infections-have a high prevalence (...) . Vaginitis caused by Candida species is the second most common vaginal infection. Hence, candidiasis is a major subject for research, including experimental in vivo models to study pathogenesis, prevention, or therapy of the disease. The following review article will focus on various experimental in vivo models in different laboratory animals, such as mammals (mice, rats, rabbits), the fruit fly-Drosophila melanogaster, the larvae of the moth Galleria mellonella, or the free-living nematode

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2018 Journal of Fungi

12. Candidiasis, Cutaneous (Diagnosis)

Candidiasis, Cutaneous (Diagnosis) Cutaneous Candidiasis: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA5MDYzMi1vdmVydmlldw== processing > Cutaneous Candidiasis Updated (...) : May 22, 2018 Author: Noah S Scheinfeld, JD, MD, FAAD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Cutaneous Candidiasis Overview Background Cutaneous candidiasis and other forms of candidosis are infections caused by the yeast Candida albicans or other Candida species. Yeasts are unicellular fungi that typically reproduce by budding, a process that entails a progeny pinching off of the mother cell. C albicans , the principal infectious agent in human

2014 eMedicine.com

13. Candidiasis, Cutaneous (Treatment)

Candidiasis, Cutaneous (Treatment) Cutaneous Candidiasis Treatment & Management: Medical Care Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA5MDYzMi10cmVhdG1lbnQ= processing > Cutaneous Candidiasis Treatment (...) & Management Updated: May 22, 2018 Author: Noah S Scheinfeld, JD, MD, FAAD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Cutaneous Candidiasis Treatment Medical Care Candidal vulvovaginitis Topical antifungal agents including miconazole nitrate (Micatin, Monistat-Derm) or clotrimazole (Lotrimin, Mycelex) creams are curative. One-time oral therapy with fluconazole (150 mg) or itraconazole (600 mg) is effective and may be a more attractive alternative to some patients

2014 eMedicine.com

14. Candidiasis, Cutaneous (Overview)

Candidiasis, Cutaneous (Overview) Cutaneous Candidiasis: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA5MDYzMi1vdmVydmlldw== processing > Cutaneous Candidiasis Updated (...) : May 22, 2018 Author: Noah S Scheinfeld, JD, MD, FAAD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Cutaneous Candidiasis Overview Background Cutaneous candidiasis and other forms of candidosis are infections caused by the yeast Candida albicans or other Candida species. Yeasts are unicellular fungi that typically reproduce by budding, a process that entails a progeny pinching off of the mother cell. C albicans , the principal infectious agent in human

2014 eMedicine.com

15. Candidiasis, Cutaneous (Follow-up)

Candidiasis, Cutaneous (Follow-up) Cutaneous Candidiasis Treatment & Management: Medical Care Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA5MDYzMi10cmVhdG1lbnQ= processing > Cutaneous Candidiasis Treatment (...) & Management Updated: May 22, 2018 Author: Noah S Scheinfeld, JD, MD, FAAD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Cutaneous Candidiasis Treatment Medical Care Candidal vulvovaginitis Topical antifungal agents including miconazole nitrate (Micatin, Monistat-Derm) or clotrimazole (Lotrimin, Mycelex) creams are curative. One-time oral therapy with fluconazole (150 mg) or itraconazole (600 mg) is effective and may be a more attractive alternative to some patients

2014 eMedicine.com

16. Candidiasis

, macerated intertriginous areas Chronic mucocutaneous Candidiasis Circumscribed hyperkeratotic skin lesions s Partial Oral and vaginal Endocrine organ hypofunction Gastrointestinal Distal esophagus ulcerations Hematogenous (Immunosuppressed) Malaise l abscess Pulmonary nodular infiltrate Endocarditis VII. Labs Abscess drainage shows candida mycelia Candida Serology titers elevated Pseudohyphae VIII. Management Cutaneous Imidazole cream Oral One troche dissolve in mouth x5 qd for 7-14 days suspension (...) of the genus Candida; usually a superficial infection of the moist areas of the body and is generally caused by Candida albicans; includes chronic mucocutaneous candidiasis, cutaneous candidiasis, oral candidiasis (thrush), and monilial vaginitis. Concepts Disease or Syndrome ( T047 ) MSH ICD9 112.9, 112 ICD10 , SnomedCT 187005005 , 187024008 , 187478002 , 154403005 , 370520002 , 78048006 English Candidiases , Candidiasis , Moniliases , Moniliasis , CANDIDIASIS , MONILIASIS , Candidiasis, unspecified , [X

2018 FP Notebook

17. A Clinician's Guide to the Diagnosis and Treatment of Candidiasis in Patients with Psoriasis. (PubMed)

A Clinician's Guide to the Diagnosis and Treatment of Candidiasis in Patients with Psoriasis. Many of the molecular pathways associated with psoriasis pathogenesis are also involved in host defense mechanisms that protect against common pathogens. Candida can stimulate the production of cytokines that trigger or exacerbate psoriasis, and many systemic psoriasis treatments may put patients at increased risk for developing oral, cutaneous, and genitourinary candidiasis. Therefore, dermatologists (...) should regularly screen patients with psoriasis for signs of Candida infection, and take steps to effectively treat these infections to prevent worsening of psoriasis symptoms. This review provides an overview of candidiasis epidemiology in patients with psoriasis, followed by a primer on the diagnosis and treatment of superficial Candida infections, with specific guidance for patients with psoriasis. Candidiasis in patients with psoriasis typically responds to topical or oral antifungal therapy

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2016 American journal of clinical dermatology

18. Efficacy and Safety in 1% Clotrimazole Powder, Adjuvant Therapy in Patients with Superficial Fungal Cutaneous Infection in Intertriginous Areas. (PubMed)

were significantly higher than the control group, as observed within four weeks (p = 0.01), especially for dermatophyte infection (p = 0.039). Two cases had recurrent candidiasis in the control group. In both groups, relapse up to 24 weeks were not statistically different. Additionally, there was no difference in patients’ satisfaction towards convenience of drug application.Using of the 1% CP could be suggested as an adjuvant therapy and possibly preventive agent for superficial fungal cutaneous (...) Efficacy and Safety in 1% Clotrimazole Powder, Adjuvant Therapy in Patients with Superficial Fungal Cutaneous Infection in Intertriginous Areas. Superficial fungal cutaneous infection is commonly found in intertriginous area.To assess 1% clotrimazole powder (1% CP) efficacy for adjuvant treatment of superficial fungal cutaneous infection in intertriginous areas.The study performed as an open-label, randomized, comparative study for evaluating the effects of 1% clotrimazole cream (1% CC) with 1

2018 Journal of the Medical Association of Thailand = Chotmaihet thangphaet

19. Cutaneous Candidiasis

Cutaneous Candidiasis Cutaneous Candidiasis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Cutaneous Candidiasis Cutaneous (...) Candidiasis Aka: Cutaneous Candidiasis From Related Chapters II. Risk Factors Systemic antibiotics Ill-fitting dentures Pregnancy Elderly III. Exam: Distribution Perioral dermatitis Cheilitis IV. Differential Diagnosis Drug allergy (HSV) (e.g. ) Dermatophyte See Differential Diagnosis for V. Management Cutaneous Candidiasis Topical anti-fungal Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Cutaneous Candidiasis." Click on the image

2015 FP Notebook

20. The biological significance of TLR3 variant, L412F, in conferring susceptibility to cutaneous candidiasis, CMV and autoimmunity. (PubMed)

The biological significance of TLR3 variant, L412F, in conferring susceptibility to cutaneous candidiasis, CMV and autoimmunity. Toll-like receptors, a major component of the innate immune system, play an important role in the initial response against pathogens. Genetic abnormalities in some receptors like TLR2, TLR3 and TLR4 have been associated with susceptibility to fungal and viral infections while other aberrations in TLR genes such as TLR3, TLR7 and TLR9 may predispose to autoimmunity (...) . Recently we have shown an association of a TLR3 receptor variant, L412F, to susceptibility to chronic candidiasis, recurrent viral and bacterial infections and autoimmunity. We investigated here the biological implications of this TLR3 mutant.To study the functional impact of the L412F variant of TLR3 we tested patients' peripheral blood mononuclear cells (PBMCs) as well as fibroblasts for secretion of cytokines in response to TLR3 ligand, candida or cytomegalovirus (CMV). In addition, the P2.1 cell

2012 Autoimmunity reviews

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