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Cryotherapy

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161. Could −79 °C Spray-Type Cryotherapy Be an Effective Monotherapy for the Treatment of Keloid? (PubMed)

Could −79 °C Spray-Type Cryotherapy Be an Effective Monotherapy for the Treatment of Keloid? Cryotherapy has been regarded as an effective modality for the treatment of keloids, and the spray-type device is one of the novel cryotherapeutic units. However, the biological mechanisms and therapeutic effects of this technique are incompletely studied. We evaluated the clinical efficacy of our cryotherapy protocol with molecular and pathologic evidence for the treatment of keloids. We evenly (...) split each of ten keloid lesions into a non-treated (C-) and treated (C+) area; the C+ area was subjected to two freeze-thaw cycles of spray-type cryotherapy using -79 °C spray-type CryoPen™. This treatment was repeated after an interval of two weeks. The proliferation and migration abilities of the fibroblasts isolated from the dermis under the cryotherapy-treated or untreated keloid tissues (at least 5 mm deep) were compared and pathologic findings of the full layer were evaluated. Molecular

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2017 International journal of molecular sciences

162. Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment: A Randomized, Controlled, Investigator-Blinded, Comparative Study (PubMed)

Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment: A Randomized, Controlled, Investigator-Blinded, Comparative Study Cutaneous warts are common skin lesions, caused by human papillomavirus. For years, liquid nitrogen is the cryogen of choice for wart treatment. Alternatively, several cryogenic devices for home treatment are commercially available. The present trial assessed efficacy and safety of a novel nitrous oxide-based cryogenic device for home use (EndWarts Freeze® (...) %). Reported side effects were transient and typical of cryotherapy. All treatments were well-tolerated.The superior cure rates for the test product versus two comparators can be explained by its design. Combination of nitrous oxide (cooling agent), the specific activation method (holding the liquid coolant in the cap), and skin-conforming polyurethane foam, results in higher cooling efficiency (- 80 °C) and more effective wart freezing. This trial demonstrated that the nitrous oxide device is a safe, user

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2017 Dermatology and therapy

163. Clinical Evaluation of the Performance of a Difluoroethane-based Cyto-selective Cryotherapy to Treat Dark Spots on the Hand in 30 Volunteers.

Clinical Evaluation of the Performance of a Difluoroethane-based Cyto-selective Cryotherapy to Treat Dark Spots on the Hand in 30 Volunteers. Clinical Evaluation of the Performance of a Difluoroethane-based Cyto-selective Cryotherapy to Treat Dark Spots on the Hand in 30 Volunteers. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save (...) this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Clinical Evaluation of the Performance of a Difluoroethane-based Cyto-selective Cryotherapy to Treat Dark Spots on the Hand in 30 Volunteers. (CBT) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details

2017 Clinical Trials

164. Breast/Evaluation of Cryotherapy and TRPA1 Receptors in Chemotherapy Induced Neuropathy

Breast/Evaluation of Cryotherapy and TRPA1 Receptors in Chemotherapy Induced Neuropathy Breast/Evaluation of Cryotherapy and TRPA1 Receptors in Chemotherapy Induced Neuropathy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Breast/Evaluation of Cryotherapy and TRPA1 Receptors in Chemotherapy Induced Neuropathy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03329131 Recruitment Status : Recruiting First Posted : November 1

2017 Clinical Trials

165. Influence of Cryotherapy Combined to TENS Burst in Patients With Non-specific Chronic Lombar Pain

Influence of Cryotherapy Combined to TENS Burst in Patients With Non-specific Chronic Lombar Pain Influence of Cryotherapy Combined to TENS Burst in Patients With Non-specific Chronic Lombar Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Influence of Cryotherapy Combined to TENS Burst in Patients With Non-specific Chronic Lombar Pain The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03111199 Recruitment Status

2017 Clinical Trials

166. Evaluation of the ClariFixâ„¢ Cryotherapy Device in Subjects With Chronic Rhinitis

Evaluation of the ClariFixâ„¢ Cryotherapy Device in Subjects With Chronic Rhinitis Evaluation of the ClariFix™ Cryotherapy Device in Subjects With Chronic Rhinitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding (...) more. Evaluation of the ClariFix™ Cryotherapy Device in Subjects With Chronic Rhinitis (FROST) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03181594 Recruitment Status : Active, not recruiting First Posted : June 9, 2017 Last Update Posted : December 31, 2018 Sponsor: Arrinex, Inc. Information

2017 Clinical Trials

167. The Effect of Cryotherapy on Cerebral Hemodynamics Within Healthy Subjects

The Effect of Cryotherapy on Cerebral Hemodynamics Within Healthy Subjects The Effect of Cryotherapy on Cerebral Hemodynamics Within Healthy Subjects - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . The Effect of Cryotherapy on Cerebral Hemodynamics Within Healthy Subjects The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03185507 Recruitment Status : Completed First Posted : June 14, 2017 Last Update Posted : August 2, 2018 Sponsor: University of Virginia Information provided by (Responsible Party

2017 Clinical Trials

168. Effect on Dynamic Postural Stability After Application of Cryotherapy to the Knee Joint

Effect on Dynamic Postural Stability After Application of Cryotherapy to the Knee Joint Effect on Dynamic Postural Stability After Application of Cryotherapy to the Knee Joint - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Effect on Dynamic Postural Stability After Application of Cryotherapy to the Knee Joint The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03151031 Recruitment Status : Completed First Posted : May 12, 2017 Last Update Posted : September 12, 2017 Sponsor: Asir John Samuel Information

2017 Clinical Trials

169. Intralesional Measles, Mumps, Rubella (MMR) Vaccine Versus Cryotherapy in Treatment of Multiple Common and Planter Warts

Intralesional Measles, Mumps, Rubella (MMR) Vaccine Versus Cryotherapy in Treatment of Multiple Common and Planter Warts Intralesional Measles, Mumps, Rubella (MMR) Vaccine Versus Cryotherapy in Treatment of Multiple Common and Planter Warts - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. Intralesional Measles, Mumps, Rubella (MMR) Vaccine Versus Cryotherapy in Treatment of Multiple Common and Planter Warts The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details

2017 Clinical Trials

170. Androgen Deprivation Therapy (ADT) Versus ADT Plus Prostate Cryotherapy for Metastatic Prostate Cancer (mPCa)

Androgen Deprivation Therapy (ADT) Versus ADT Plus Prostate Cryotherapy for Metastatic Prostate Cancer (mPCa) Androgen Deprivation Therapy (ADT) Versus ADT Plus Prostate Cryotherapy for Metastatic Prostate Cancer (mPCa) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (...) (100). Please remove one or more studies before adding more. Androgen Deprivation Therapy (ADT) Versus ADT Plus Prostate Cryotherapy for Metastatic Prostate Cancer (mPCa) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier

2017 Clinical Trials

171. Clinical Study : Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment

Clinical Study : Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment Clinical Study : Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Clinical Study : Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03129373 Recruitment Status : Completed First Posted : April 26, 2017 Last Update Posted : September 19, 2017 Sponsor: Oystershell NV Information provided

2017 Clinical Trials

172. Carbon Dioxide Laser and Cryotherapy in Treatment of Warts

Carbon Dioxide Laser and Cryotherapy in Treatment of Warts Carbon Dioxide Laser and Cryotherapy in Treatment of Warts - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Carbon Dioxide Laser and Cryotherapy (...) Intervention/treatment Phase Common Warts Device: Carbon dioxide laser Device: Cryotherapy Not Applicable Detailed Description: A range of types of wart have been identified, varying in shape and site affected, as well as the type of human papillomavirus involved. These include: Common wart (Verruca vulgaris). Flat wart (Verruca plana). Filiform or digitate wart. Genital wart (venereal wart, Condyloma acuminatum, Verruca acuminata). Mosaic wart. Periungual wart. Plantar wart (verruca, Verruca plantaris

2017 Clinical Trials

173. Comparison Between Tuberculin Vaccine and Cryotherapy in Genital Wart Patients

Comparison Between Tuberculin Vaccine and Cryotherapy in Genital Wart Patients Comparison Between Tuberculin Vaccine and Cryotherapy in Genital Wart Patients - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Comparison Between Tuberculin Vaccine and Cryotherapy in Genital Wart Patients The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03153566 Recruitment Status : Not yet recruiting First Posted : May 15, 2017 Last Update Posted

2017 Clinical Trials

174. Cryotherapy in gastrointestinal endoscopy (PubMed)

Cryotherapy in gastrointestinal endoscopy 29905303 2018 11 14 2468-4481 2 5 2017 May VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy VideoGIE Cryotherapy in gastrointestinal endoscopy. 89-95 10.1016/j.vgie.2017.01.021 ASGE Technology Committee Parsi Mansour A MA Trindade Arvind J AJ Bhutani Manoop S MS Melson Joshua J Navaneethan Udayakumar U Thosani Nirav N Trikudanathan Guru G Watson Rabindra R RR Maple John T JT eng Journal Article 2017 02 06

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2017 VideoGIE

175. The Effect of Cryotherapy in Hailey-Hailey Disease (PubMed)

The Effect of Cryotherapy in Hailey-Hailey Disease 28223763 2018 11 13 1013-9087 29 1 2017 Feb Annals of dermatology Ann Dermatol The Effect of Cryotherapy in Hailey-Hailey Disease. 117-118 10.5021/ad.2017.29.1.117 Son Jee Hee JH Department of Dermatology, Hallym University College of Medicine, Seoul, Korea. Cho Yong Se YS Department of Dermatology, Hallym University College of Medicine, Seoul, Korea. Byun Yun Sun YS Department of Dermatology, Hallym University College of Medicine, Seoul, Korea

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2017 Annals of dermatology

176. CORR Insights®: Freezing Nitrogen Ethanol Composite May be a Viable Approach for Cryotherapy of Human Giant Cell Tumor of Bone (PubMed)

CORR Insights®: Freezing Nitrogen Ethanol Composite May be a Viable Approach for Cryotherapy of Human Giant Cell Tumor of Bone 28243975 2017 11 20 2018 12 02 1528-1132 475 6 2017 06 Clinical orthopaedics and related research Clin. Orthop. Relat. Res. CORR Insights ® : Freezing Nitrogen Ethanol Composite May be a Viable Approach for Cryotherapy of Human Giant Cell Tumor of Bone. 1664-1667 10.1007/s11999-017-5292-y Healey John H JH Orthopaedic Service, Department of Surgery, Memorial Sloan (...) Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA. healeyj@mskcc.org. eng Journal Article Comment 2017 02 27 United States Clin Orthop Relat Res 0075674 0009-921X 3K9958V90M Ethanol N762921K75 Nitrogen AIM IM Clin Orthop Relat Res. 2017 Jun;475(6):1650-1663 28197783 Bone Neoplasms Cryotherapy Ethanol Freezing Giant Cell Tumor of Bone Humans Nitrogen 2017 01 26 2017 02 17 2017 3 1 6 0 2017 11 29 6 0 2017 3 1 6 0 ppublish 28243975 10.1007/s11999-017-5292-y 10.1007/s11999-017-5292-y

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2017 Clinical Orthopaedics and Related Research

177. A Comparative Study of Liquid Nitrogen Cryotherapy as Monotherapy versus in Combination with Podophyllin in the Treatment of Condyloma Acuminata (PubMed)

A Comparative Study of Liquid Nitrogen Cryotherapy as Monotherapy versus in Combination with Podophyllin in the Treatment of Condyloma Acuminata Condyloma Acuminata (CA) is a common viral sexually transmitted disease. Although various treatment modalities are available for treating CA, but none of them can achieve 100% response rate. In a search for better response rate and less recurrence rate, the combination of cytotoxic agent Podophyllin with ablative liquid nitrogen cryotherapy (...) was evaluated over cryotherapy alone.To evaluate the synergistic effect of Podophyllin as a chemotherapeutic adjunct to an ablative therapy of liquid nitrogen cryotherapy versus liquid nitrogen cryotherapy alone in the treatment of CA.Sixty patients with multiple CA were randomly assigned to two groups in the study. Thirty patients in group A received double freeze thaw cycle of 25 seconds of liquid nitrogen cryotherapy. Thirty patients in Group B were subjected to liquid nitrogen cryotherapy in a similar

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2017 Journal of clinical and diagnostic research : JCDR

178. A Computerized Tutor Prototype for Prostate Cryotherapy: Key Building Blocks and System Evaluation (PubMed)

A Computerized Tutor Prototype for Prostate Cryotherapy: Key Building Blocks and System Evaluation This paper focuses on the evaluation of a prototype for a computer-based tutoring system for prostate cryosurgery, while reviewing its key building blocks and their benchmark performance. The tutoring system lists geometrical constraints of cryoprobe placement, displays a rendered shape of the prostate, simulates cryoprobe insertion, enables distance measurements, simulates the corresponding (...) outside of the operation room. System validation of the tutor has been performed by collecting training data from surgical residents, having no prior experience or advanced knowledge of cryotherapy. Furthermore, the system has been evaluated by graduate engineering students having no formal education in medicine. In terms of match between a planning isotherm and the target region shape, results demonstrate medical residents' performance improved from 4.4% in a pretest to 37.8% in a posttest over

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2017 Proceedings of SPIE--the International Society for Optical Engineering

179. Current status of spray cryotherapy for airway disease (PubMed)

Current status of spray cryotherapy for airway disease The use of liquid nitrogen to treat skin and mucosal lesions is well understood in the dermatologic and gastrointestinal literature. Direct spray cryotherapy (SCT) in the airway has shown promising results in the treatment of esophageal premalignant and even invasive lesions. In the airway, several studies have shown it to be a safe, effective treatment for both benign and malignant disease. It is easily administered in the outpatient (...) principals behind the use of the cryotherapy to treat lesions in different tissues. We feel that SCT is a potential area for further research at both clinical and basic science level.

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2017 Journal of thoracic disease

180. A Non–Gas-Based Cryotherapy System for the Treatment of Cervical Intraepithelial Neoplasia: A Mixed-Methods Approach for Initial Development and Testing (PubMed)

A Non–Gas-Based Cryotherapy System for the Treatment of Cervical Intraepithelial Neoplasia: A Mixed-Methods Approach for Initial Development and Testing Gas-based cryotherapy is the most widely used treatment strategy for cervical intraepithelial neoplasia (CIN) in low-resource settings, but reliance on gas presents challenges in low- and middle-income countries (LMICs). Our team adapted the original CryoPen Cryosurgical System, a cryotherapy device that does not require compressed gas (...) the adapted CryoPen and the standard cryotherapy device. In 80% of the cases in the pilot study, the adapted CryoPen achieved the target depth of necrosis 3.5 mm established in the pathology review.The LMIC-adapted CryoPen overcomes barriers to standard gas-based cryotherapy by eliminating dependency on gas, increasing portability, and ensuring consistent freeze temperatures. Further testing and evaluation of the adapted CryoPen will be pursued to assess scalability and potential impact of this device

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2017 Global Health: Science and Practice

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