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Cryotherapy

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121. The Effects of Cryotherapy on Knee Joint Position Sense and Force Production Sense in Healthy Individuals Full Text available with Trip Pro

The Effects of Cryotherapy on Knee Joint Position Sense and Force Production Sense in Healthy Individuals The proprioceptive information received from mechanoreceptors is potentially responsible for controlling the joint position and force differentiation. However, it is unknown whether cryotherapy influences this complex mechanism. Previously reported results are not universally conclusive and sometimes even contradictory. The main objective of this study was to investigate the impact of local (...) cryotherapy on knee joint position sense (JPS) and force production sense (FPS). The study group consisted of 55 healthy participants (age: 21 ± 2 years, body height: 171.2 ± 9 cm, body mass: 63.3 ± 12 kg, BMI: 21.5 ± 2.6). Local cooling was achieved with the use of gel-packs cooled to -2 ± 2.5°C and applied simultaneously over the knee joint and the quadriceps femoris muscle for 20 minutes. JPS and FPS were evaluated using the Biodex System 4 Pro apparatus. Repeated measures analysis of variance (ANOVA

2018 Journal of human kinetics

122. Comparative Effectiveness of Conservative Management Compared to Cryotherapy in Localized Prostate Cancer Patients Full Text available with Trip Pro

Comparative Effectiveness of Conservative Management Compared to Cryotherapy in Localized Prostate Cancer Patients The high frequency of treatment-related side effects for men with localized prostate cancer creates uncertainty for treatment outcomes. This study assessed the comparative effectiveness of treatment-related side effects associated with conservative management and cryotherapy in patients with localized prostate cancer. A retrospective longitudinal cohort study was conducted, using (...) in the conservative management and cryotherapy cohort, respectively. The likelihood of erectile dysfunction, lower urinary tract obstruction, urinary fistula, urinary incontinence, and hydronephrosis was reported to be significantly lower (53%, 35%, 69%, 65%, and 36%, respectively) in the conservative management cohort. Conservative management had a lower likelihood of treatment-related side effects compared to cryotherapy. However, further research is needed to compare other significant long-term outcomes

2018 American journal of men's health

123. Cold panniculitis: Adverse cutaneous effect of whole-body cryotherapy Full Text available with Trip Pro

Cold panniculitis: Adverse cutaneous effect of whole-body cryotherapy 29693065 2019 02 26 2352-5126 4 4 2018 May JAAD case reports JAAD Case Rep Cold panniculitis: Adverse cutaneous effect of whole-body cryotherapy. 344-345 10.1016/j.jdcr.2018.02.010 Greenwald Elizabeth E Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York. Christman Mitalee M Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New (...) York. Penn Lauren L Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York. Brinster Nooshin N Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York. Liebman Tracey N TN Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York. eng Case Reports 2018 04 01 United States JAAD Case Rep 101665210 2352-5126 WBC, whole-body cryotherapy adverse cutaneous

2018 JAAD Case Reports

124. Immunotherapy Plus Cryotherapy: Potential Augmented Abscopal Effect for Advanced Cancers Full Text available with Trip Pro

Immunotherapy Plus Cryotherapy: Potential Augmented Abscopal Effect for Advanced Cancers Since the 1920s the gold standard for treating cancer has been surgery, which is typically preceded or followed with chemotherapy and/or radiation, a process that perhaps contributes to the destruction of a patient's immune defense system. Cryosurgery ablation of a solid tumor is mechanistically similar to a vaccination where hundreds of unique antigens from a heterogeneous population of tumor cells derived

2018 Frontiers in oncology

125. Local cryotherapy improves adjuvant-induced arthritis through down-regulation of IL-6 / IL-17 pathway but independently of TNFα. Full Text available with Trip Pro

Local cryotherapy improves adjuvant-induced arthritis through down-regulation of IL-6 / IL-17 pathway but independently of TNFα. Local cryotherapy is widely and empirically used in the adjuvant setting in rheumatoid arthritis treatment, however its own therapeutic and anti-inflammatory effects are poorly characterized. We aimed to evaluate the effects of local cryotherapy on local and systemic inflammation in Adjuvant-induced arthritis, a murine model of rheumatoid arthritis.The effects of mild (...) hypothermia (30°C for 2 hours) on cytokine protein levels (Multiplex/ELISA) were evaluated in vitro in cultured rat adjuvant-induced arthritis patellae. In vivo, local cryotherapy was applied twice a day for 14 days in arthritic rats (ice: n = 10, cold gas: n = 9, non-treated: n = 10). At day 24 after the induction of arthritis, cytokine expression levels were measured in grinded hind paws (Q-RT-PCR) and in the plasma (Multiplex/ELISA).In vitro, punctual mild hypothermia down-regulated IL-6 protein

2017 PLoS ONE

126. Treatment of cryotherapy and orthotopic transplantation following chondromyxoid fibroma of zygomatic bone: A case report. Full Text available with Trip Pro

, and then the following steps were adopted: firstly, the tumor was extensively excised; secondly, in vitro tumor excochleation was conducted; thirdly, the excised tumor bone was placed in liquid nitrogen for 3 cycles of cryoablation; finally, the orthotopic transplantation was performed to reconstruct the zygomatic appearance, with satisfactory follow-up efficacy obtained.Orthotopic transplantation after tumorectomy and cryopreservation of tumor bone in liquid nitrogen could lead to excellent therapeutic efficacy (...) Treatment of cryotherapy and orthotopic transplantation following chondromyxoid fibroma of zygomatic bone: A case report. Chondromyxoid fibrotherma (CMF) is a rare benign cartilage tumor that occurs more frequently in young males at the age of 20 to 30. It occurs more frequently on long bones, but rarely involves craniofacial bones.This study mainly introduced a 30-year-old male with CMF of zygomatic bone. Single tumor excochleation was conducted initially. However, CMF reoccurred

2018 Medicine

127. Sequential treatment of actinic keratosis with cryotherapy and ingenol mebutate: reflectance confocal microscopy monitoring of efficacy and local skin reaction. (Abstract)

Sequential treatment of actinic keratosis with cryotherapy and ingenol mebutate: reflectance confocal microscopy monitoring of efficacy and local skin reaction. Sequential treatment of actinic keratosis (AK) and cancerization field with cryotherapy and ingenol mebutate (IM) is widely used in clinical practice, however, the order of application of sequential treatment has not been examined yet.To compare different sequential treatments of IM and cryotherapy in AK and to monitor cure rates (...) and local skin reactions (LSR) through reflectance confocal microscopy (RCM).Patients with AK were treated with IM and cryotherapy. Group A received treatment with IM before cryotherapy, and group B patients were firstly treated with cryotherapy and secondly IM. RCM evaluation of epidermal dysplasia and LSR was performed prior to the first treatment (Week 0), before the second treatment (Week 2), and one month and two months after initial assessment.The study included 26 patients - 14 patients in group

2018 International Journal of Dermatology

128. Cryotherapy relieves pain and edema following inguinal hernioplasty in males with end-stage renal disease: A prospective randomized study. Full Text available with Trip Pro

Cryotherapy relieves pain and edema following inguinal hernioplasty in males with end-stage renal disease: A prospective randomized study. Tension-free hernioplasty under local anesthetic infiltration is a reasonable choice for end-stage renal disease patients with hernia.The purpose of the study was to investigate the feasibility of cryotherapy after hernioplasty surgery to relieve pain and scrotal edema.This was a prospective, randomized, and controlled trial held in a large integrated health (...) frequency of adverse effects, cryotherapy is useful for end-stage renal disease populations after hernioplasty to relieve pain and scrotal edema.Copyright © 2018 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

2018 Journal of pain and symptom management Controlled trial quality: uncertain

129. The efficacy and safety of other cryotherapy compounds for the treatment of genital warts: A randomized controlled trial. (Abstract)

who were referred to a dermatology clinic at Tehran University of Medical Sciences. Two genital warts of each patient were selected and randomly assigned to receive either Wartner (intervention) or liquid nitrogen (control).Two weeks after the treatment, the sizes of the lesions in control and intervention groups decreased by 17.87 ± 2.14 mm2 and 15.81 ± 1.80 mm2, respectively (p = .299). Fourteen days after a single session of treatment, 81% of lesions in the control group and 50% in the Wartner (...) The efficacy and safety of other cryotherapy compounds for the treatment of genital warts: A randomized controlled trial. Cryotherapy using Wartner compound that contains a mixture of dimethyl ether (75%) and propane (25%) has been recently reported as an effective treatment for warts. The present study aimed to evaluate the safety and efficacy of Wartner in male patients with genital warts.A Phase II parallel-randomized clinical trial was performed on 16 Iranian men affected by genital warts

2018 Journal of Dermatological Treatment Controlled trial quality: uncertain

130. Reduced opiate use after total knee arthroplasty using computer-assisted cryotherapy. (Abstract)

Reduced opiate use after total knee arthroplasty using computer-assisted cryotherapy. Despite multimodal pain management and advances in anesthetic techniques, total knee arthroplasty (TKA) remains painful during the early postoperative phase. This trial investigated whether computer-assisted cryotherapy (CAC) is effective in reduction of pain and consumption of opioids in patients operated for TKA following an outpatient surgery pathway.Sixty patients scheduled for primary TKA were included (...) in this prospective, double-blind, randomized controlled trial receiving CAC at 10-12 °C (Cold-group, n = 30) or at 21 °C (Warm-group, n = 30) during the first 7 days after TKA according to a fixed schedule. All patients received the same pre-, peri- and postoperative care with a multimodal pain protocol. Pain was assessed before and after every session of cryotherapy using the numerical rating scale for pain (NRS-pain). The consumption of opioids was strictly noted during the first 4 postoperative days

2018 Knee Surgery, Sports Traumatology, Arthroscopy Controlled trial quality: predicted high

131. Evaluating the Therapeutic Success of Keloids Treated With Cryotherapy and Intralesional Corticosteroids Using Noninvasive Objective Measures. (Abstract)

Evaluating the Therapeutic Success of Keloids Treated With Cryotherapy and Intralesional Corticosteroids Using Noninvasive Objective Measures. Intralesional corticosteroid injections combined with cryotherapy are considered a first-line therapy for keloids. However, objective evaluation on its efficacy is widely missing.In this study, the authors evaluated the therapeutic benefits of cryotherapy directly followed by intralesional crystalline triamcinolone acetonide injections using ultrasound (...) and a 3D topographic imaging device.Fifteen patients with keloids were treated with cryotherapy and intralesional injections of triamcinolone acetonide for a total of 4 times at intervals of 4 weeks. Objective assessment was performed at each visit.After the last treatment, a significant average reduction of scar volume of 34.3% and an average decrease in scar height of 41.3% as determined by 3D imaging was observed compared with baseline. Ultrasound revealed an average reduction of scar height of 31.7

2018 Dermatologic Surgery

132. Effect of whole body cryotherapy interventions on health-related quality of life in fibromyalgia patients: A randomized controlled trial. (Abstract)

Effect of whole body cryotherapy interventions on health-related quality of life in fibromyalgia patients: A randomized controlled trial. Although fibromyalgia syndrome (SFM) affects 2-4 percent of adults, research has not identified a preferred therapeutic option for patients worldwide yet. Based on recent findings, it can be expected that whole body cryotherapy can improve health-reported quality of life by alleviating the symptoms of musculoskeletal pain and fatigue.Our aim was to determine (...) whether whole body cryotherapy only can result in improved perceived health and quality of life in fibromyalgia patients.24 patients with fibromyalgia diagnosis were randomized into 2 groups (n=11 in the whole body cryotherapy group, n=13 in the control group). In the whole body cryotherapy group, 10 sessions of whole body cryotherapy were performed (in addition to usual care) in a standard cryotherapy room over a duration of 8days. Subjects in the control group did not change anything

2018 Complementary Therapies In Medicine Controlled trial quality: uncertain

133. Effects of Various Cryotherapy Applications on Postoperative Pain in Molar Teeth with Symptomatic Apical Periodontitis: A Preliminary Randomized Prospective Clinical Trial. (Abstract)

Effects of Various Cryotherapy Applications on Postoperative Pain in Molar Teeth with Symptomatic Apical Periodontitis: A Preliminary Randomized Prospective Clinical Trial. The purpose of the study was to evaluate the effects of intracanal, intraoral, and extraoral cryotherapy on postoperative pain in molar teeth with symptomatic apical periodontitis.A total of 100 patients were randomly distributed into 4 groups: control (without cryotherapy application), intracanal cryotherapy application (...) , intraoral cryotherapy application, and extraoral cryotherapy application. The postoperative pain of the patients was recorded at the first, third, fifth, and seventh days. The data were statistically analyzed by using linear regression, χ2, one-way analysis of variance, Tukey post hoc, and Kruskal-Wallis H tests (P = .05).There were no statistically significant differences among the groups in terms of demographic data (P > .05). The preoperative pain levels and preoperative visual analogue scale (VAS

2018 Journal of Endodontics Controlled trial quality: uncertain

134. Different Cryotherapy Techniques for Skin Surface Temperature, Agility and Balance of Active Youth

Different Cryotherapy Techniques for Skin Surface Temperature, Agility and Balance of Active Youth Different Cryotherapy Techniques for Skin Surface Temperature, Agility and Balance of Active Youth - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Different Cryotherapy Techniques for Skin Surface Temperature, Agility and Balance of Active Youth The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03659474 Recruitment Status : Completed First Posted : September 6, 2018 Last Update Posted : September 6, 2018

2018 Clinical Trials

135. Effect of Two Methods for the Application of Cryotherapy

Effect of Two Methods for the Application of Cryotherapy Effect of Two Methods for the Application of Cryotherapy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effect of Two Methods for the Application (...) of Cryotherapy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03707327 Recruitment Status : Not yet recruiting First Posted : October 16, 2018 Last Update Posted : October 16, 2018 See Sponsor: Universidade Estadual de Londrina

2018 Clinical Trials

136. Cryotherapy Against Oral Mucositis After High-dose Melphalan

Cryotherapy Against Oral Mucositis After High-dose Melphalan Cryotherapy Against Oral Mucositis After High-dose Melphalan - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Cryotherapy Against Oral Mucositis (...) Johansson, Sahlgrenska University Hospital, Sweden Study Details Study Description Go to Brief Summary: In this prospective, randomised, controlled, open-label, Phase III, non-inferiority clinical trial trial patients with a diagnosis of myeloma who were undergoing autologous HSCT were randomised 1:1 to receive cryotherapy for 7 hours or 2 hours . Oral mucositis was evaluated prospectively. Condition or disease Intervention/treatment Phase Myeloma Mucositis Cryotherapy Effect Other: cryotherapy

2018 Clinical Trials

137. Efficacy and safety of cryotherapy versus electrosurgery in the treatment of cherry angioma. (Abstract)

Efficacy and safety of cryotherapy versus electrosurgery in the treatment of cherry angioma. 29524266 2018 08 23 1468-3083 32 9 2018 Sep Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Efficacy and safety of cryotherapy vs. electrosurgery in the treatment of cherry angioma. e361-e363 10.1111/jdv.14936 Robati R M RM http://orcid.org/0000-0002-7947-8642 Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Ghasemi

2018 Journal of the European Academy of Dermatology and Venereology

138. Cryotherapy in the management of premalignant and malignant conditions of the esophagus Full Text available with Trip Pro

Cryotherapy in the management of premalignant and malignant conditions of the esophagus Endoscopic cryotherapy is a relatively new thermal ablative modality used for the treatment of neoplastic lesions of the esophagus. It relies on cycles of rapid cooling and thawing to induce tissue destruction with a cryogen (liquid nitrogen or carbon dioxide) leading to intra and extra-cellular damage. Surgical treatment was once considered the standard therapeutic intervention for neoplastic diseases (...) of the esophagus and is associated with considerable rates of morbidity and mortality. Several trials that evaluated cryotherapy in Barrett's esophagus (BE) associated neoplasia showed reasonable efficacy rates and safety profile. Cryotherapy has also found applications in the treatment of esophageal cancer, both for curative and palliative intent. Cryotherapy has also shown promising results as salvage therapy in cases refractory to radiofrequency ablation treatment. Cryoballoon focal ablation using liquid

2018 World Journal of Gastroenterology

139. Cryotherapy Effectiveness in Individuals With End Stage Knee Osteoarthritis

Cryotherapy Effectiveness in Individuals With End Stage Knee Osteoarthritis Cryotherapy Effectiveness in Individuals With End Stage Knee Osteoarthritis - a Case Series - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Cryotherapy Effectiveness in Individuals With End Stage Knee Osteoarthritis - a Case Series The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03582644 Recruitment Status : Recruiting First Posted : July 11, 2018

2018 Clinical Trials

140. The effects of cryotherapy on vocal fold healing in a rabbit model. (Abstract)

The effects of cryotherapy on vocal fold healing in a rabbit model. Cryotherapy has been shown to be a scarless treatment modality for dermal lesions; however, there are limited data addressing the effect of cryotherapy on vocal fold tissue. The aim of this study was to clarify the effectiveness of cryotherapy for prevention of postsurgical vocal fold scarring.Prospective animal study in rabbits.The lamina propria of 20 rabbit vocal folds was bilaterally stripped, followed by randomized (...) unilateral cryotherapy. Five larynges were harvested for real-time polymerase chain reaction (RT-PCR) analysis at 1 day, 3 days, and 7 days postinjury. The remaining five were harvested for histologic analysis at 3 months. Images of the healing phase were recorded by laryngoscopy. Analyses of RT-PCR for cyclooxygenase (COX)-2, interleukin (IL)-6, collagen I, collagen III, matrix metallopeptidase 1 (MMP1), transforming growth factor β (TGFβ1), α smooth muscle actin (α-SMA), and hyaluronan synthase 1 (HAS1

2018 Laryngoscope

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