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Cryotherapy

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41. Oral Cryotherapy Reduces the Prevalence of Oral Mucositis in Adults Receiving Chemotherapy

Oral Cryotherapy Reduces the Prevalence of Oral Mucositis in Adults Receiving Chemotherapy UTCAT3029, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Oral Cryotherapy Reduces the Prevalence of Oral Mucositis in Adults Receiving Chemotherapy Clinical Question Does oral cryotherapy reduce the prevalence of oral mucositis in adults receiving chemotherapy? Clinical Bottom Line In adult patients undergoing chemotherapy (...) , oral cryotherapy treatment reduces the presence of oral mucositis. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Riley/2015 1280 patients undergoing cancer treatment in 14 RCTs Systematic review of randomized trials Key results Adults receiving chemotherapy treatment along with oral cryotherapy showed a reduction in oral mucositis of any severity when compared to the control of standard care

2016 UTHSCSA Dental School CAT Library

42. Oral cryotherapy: preventing mouth soreness and ulcers in people having cancer treatments

Oral cryotherapy: preventing mouth soreness and ulcers in people having cancer treatments Oral cryotherapy: preventing mouth soreness and ulcers in people having cancer treatments - Evidently Cochrane Search and hit Go By January 15, 2016 // Oral mucositis is a common side effect of high-dose chemotherapy: can cryotherapy help? It’s a long time since I worked on a children’s cancer ward, but I do remember that sore mouths were a miserable problem for many and that we did several things to help (...) prevent ulceration, including giving the children ice chips to suck. So I was interested to see a brand new Cochrane review investigating whether making the mouth cold (with ice, iced water, ice cream or ice lollies) is effective in preventing ulceration in people having cancer treatments. Properly termed oral cryotherapy, it’s free, it’s simple, it’s natural, but does it work? It would be good to know. It’s not just a sore mouth Oral mucositis is a common side effect of high-dose chemotherapy

2016 Evidently Cochrane

43. Costs and cost-effectiveness of LEEP versus cryotherapy for treating cervical dysplasia among HIV-positive women in Johannesburg, South Africa. Full Text available with Trip Pro

Costs and cost-effectiveness of LEEP versus cryotherapy for treating cervical dysplasia among HIV-positive women in Johannesburg, South Africa. Cervical cancer incidence is significant in countries, such as South Africa, with high burdens of both HIV and human papillomavirus (HPV). Cervical cancer is largely preventable if dysplasia is diagnosed and treated early, but there is debate regarding the best approaches for screening and treatment, especially for low-resource settings. Currently South (...) previously at the study facility. In the trial, women who were diagnosed with CIN2+ and eligible for cryotherapy were randomized to cryotherapy or LEEP. If women were CIN2+ at six months as determined via Pap smear and colposcopic biopsy, all women-regardless of their original treatment assignment-received LEEP. "Cure" was then defined as the absence of disease at 12 months based on Pap smear and colposcopic biopsy. Health service costs were estimated using micro-costing between June 2013 and April 2014

2018 PLoS ONE

44. Salvage image guided radiation therapy to the prostate after cryotherapy failure Full Text available with Trip Pro

Salvage image guided radiation therapy to the prostate after cryotherapy failure Cryotherapy is an option for the primary treatment of localized prostate cancer, along with radical prostatectomy, external beam radiation therapy, and brachytherapy. Although it is known that local recurrence can occur in >20% of patients treated with primary cryotherapy, unfortunately there is a paucity of data on later salvage treatments. The use of external beam radiation therapy is an attractive option after (...) cryotherapy failure, but there is little data on its efficacy and toxicity. We evaluated the biochemical control and complication rates of salvage dose-escalated image guided intensity modulated radiation therapy (IG-IMRT) after cryotherapy failure.Patients who were treated at our institution from 2005 to 2016 were reviewed for those who underwent cryotherapy as initial treatment followed by salvage IGRT. Patients were treated with dose-escalated IG-IMRT using standard treatment margins of 3 mm posterior

2017 Advances in radiation oncology

45. Cryotherapy: it’s cool, but is it evidence-based?

can see if there is any evidence to justify spending a lot of money to make ourselves very, very cold. It’s really important to know too whether cryotherapy might do any damage. What is whole-body cryotherapy? It’s colder in a cryotherapy tank than in Antarctica, the coldest place on earth Exposure to very cold dry air (usually liquid nitrogen or refrigerated cold air), below -100 ° C, for two to four minutes. This is very, very cold. Antarctica, which NASA recorded as the world’s coldest spot (...) Cryotherapy: it’s cool, but is it evidence-based? Cryotherapy: it's cool, but is it evidence-based? - Evidently Cochrane Search and hit Go By September 30, 2015 // ‘Freeze yourself fit!’ ‘Coolest new health craze!’ It seems that people can’t wait to get into a chiller and then share their freezer selfies on social media. Cryotherapy is on the up as the cool way to promote wellbeing, soothe overworked muscles and more. The Welsh rugby team, as yesterday, says cryotherapy played a big part

2015 Evidently Cochrane

46. Cryotherapy for liver metastases. (Abstract)

Cryotherapy for liver metastases. Primary liver tumours and liver metastases from colorectal carcinoma are the two most common malignant tumours to affect the liver. The liver is second only to the lymph nodes as the most common site for metastatic disease. More than half of the patients with metastatic liver disease will die from metastatic complications. In cryoablation, liquid nitrogen or argon gas is delivered to the liver tumour, guided by ultrasound using a specially designed probe. Ice (...) crystal formation during the rapid freezing process causes destruction of cellular structure and kills the tumour cells.To study the beneficial and harmful effects of cryotherapy compared with no intervention, other ablation methods, or systemic treatments in patients with liver metastases.We searched the Cochrane Hepato-Biliary Group Controlled Trials Register, The Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library, MEDLINE, EMBASE, Science Citation Index Expanded

2013 Cochrane

47. Evaluation of two alternative ablation treatments for cervical pre-cancer against standard gas-based cryotherapy: a randomized non-inferiority study. (Abstract)

Evaluation of two alternative ablation treatments for cervical pre-cancer against standard gas-based cryotherapy: a randomized non-inferiority study. Gas-based cryotherapy is the conventional ablative treatment for cervical pre-cancer in low-income settings, but the use of gas poses significant challenges. We compared the depth of necrosis induced by gas-based cryotherapy with two gas-free alternatives: cryotherapy using CryoPen,and thermoablation.We conducted a five-arm randomized non (...) -inferiority trial: double-freeze carbon dioxide (CO2) cryotherapy (referent), single-freeze CO2 cryotherapy, double-freeze CryoPen, single-freeze CryoPen, and thermoablation. Subjects were 130 women scheduled for hysterectomy for indications other than cervical pathology, and thus with healthy cervical tissue available for histological evaluation of depth of necrosis post-surgery. The null hypothesis was rejected (ie, conclude non-inferiority) if the upper bound of the 90% confidence interval (90% CI

2019 International journal of gynecological cancer : official journal of the International Gynecological Cancer Society Controlled trial quality: uncertain

48. Perfusion of the skin's microcirculation after cold-water immersion (10°C) and partial-body cryotherapy (-135°C). Full Text available with Trip Pro

Perfusion of the skin's microcirculation after cold-water immersion (10°C) and partial-body cryotherapy (-135°C). Investigations of the perfusion of the skin's microcirculation with laser speckle contrast imaging (LSCI) after cold treatments are rare. Therefore, the aim of this study was to compare the effects between cold-water immersion (CWI) conduction and partial-body cryotherapy (PBC) convection on perfusion of the microcirculation and skin temperature on the thigh.Twenty healthy males

2019 Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) Controlled trial quality: uncertain

49. Cryotherapy Reduced Postoperative Pain in Gynecologic Surgery: A Randomized Controlled Trial. Full Text available with Trip Pro

Cryotherapy Reduced Postoperative Pain in Gynecologic Surgery: A Randomized Controlled Trial. To examine the effectiveness of cryotherapy for reducing postoperative pain in patients who underwent exploratory laparotomy for gynecologic surgery.Patients who had indication for an exploratory laparotomy gynecologic procedure were selected by attending physicians to undergo abdominal surgery via low transverse skin incision. The participants were randomized into study and control groups with simple

2019 Pain research and treatment Controlled trial quality: uncertain

50. Ultrasonography effectiveness of the vibration vs cryotherapy added to an eccentric exercise protocol in patients with chronic mid-portion Achilles tendinopathy: A randomised clinical trial. (Abstract)

Ultrasonography effectiveness of the vibration vs cryotherapy added to an eccentric exercise protocol in patients with chronic mid-portion Achilles tendinopathy: A randomised clinical trial. Tendinopathy is a very common disease in the general population as well as in athletes. The aim of the present study was to examine the tendon thickness and cross-sectional area (CSA) in subjects with chronic mid-portion Achilles tendinopathy (AT) who engaged in either an eccentric exercise (EE) programme (...) with vibration training or an EE programme combined with cryotherapy. A sample of 61 patients with chronic mid-portion AT were recruited and divided into two groups: EE programme vibration training (n = 30) and EE programme combined with cryotherapy (n = 31). Three ultrasound assessments were performed: pre-intervention and at 4, and at 12 weeks. The comparison of thickness and CSA measures at baseline, 4, and 12 weeks showed a significant (P < 0.05) increase at 0, 2, 4, and 6 cm in maximal isometric

2019 International wound journal Controlled trial quality: uncertain

51. No Effect of Partial-Body Cryotherapy on Restoration of Countermovement-Jump or Well-Being Performance in Elite Rugby Union Players During the Competitive Phase of the Season. (Abstract)

No Effect of Partial-Body Cryotherapy on Restoration of Countermovement-Jump or Well-Being Performance in Elite Rugby Union Players During the Competitive Phase of the Season. Partial body cryotherapy (PBC) has been shown to be beneficial for post-exercise recovery, however, no study has demonstrated the effectiveness of PBC as a recovery modality following elite rugby union (RU) training. RU is a unique sport that involves high velocity collisions with minimal protective wear and may represent (...) . 0.01 ± 0.16%), sleep quality (-0.03 ± 0.14% vs 0.10 ± 0.29%) or CMJ height (36.48 to 36.59 vs 38.13 to 37.52 cm; p = 0.54).These results suggest that the administration of PBC is ineffective at enabling the restoration of selected performance parameters during the performance maintenance phase of the competitive season. To ascertain the appropriation of its use, future investigations should seek to assess the use of cryotherapies at various phases of the elite rugby union competitive season.

2019 International journal of sports physiology and performance Controlled trial quality: uncertain

52. Oral cryotherapy for oral mucositis management in patients receiving allogeneic hematopoietic stem cell transplantation: a prospective randomized study. (Abstract)

Oral cryotherapy for oral mucositis management in patients receiving allogeneic hematopoietic stem cell transplantation: a prospective randomized study. To explore the best schedule of oral cryotherapy for the prevention of oral mucositis in recipients of myeloablative hematopoietic stem cell transplantation (HSCT).A prospective randomized study was conducted to recruit allogeneic HSCT recipients, who were then randomly allocated into four arms to accept the following: oral cryotherapy during (...) the whole course (arm A) or second half of the course (arm B) of cytotoxic agents administration, regular oral cryotherapy twice a day (arm C), or conventional oral care without cryotherapy (arm D). Status of oral mucositis was daily assessed from the first day of conditioning to the 15th day post-HSCT. A myeloablative conditioning regimen was used which was composed of busulfan, cyclophosphamide, and cytarabine.Totally 160 cases were consecutively enrolled in this study, and 145 cases were eligible

2019 Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer Controlled trial quality: uncertain

53. Factors affecting survival in patients with endobronchial malignant mass after flexible Bronchoscopic cryotherapy: a cohort study. Full Text available with Trip Pro

Factors affecting survival in patients with endobronchial malignant mass after flexible Bronchoscopic cryotherapy: a cohort study. Malignant endobronchial mass (MEM) has poor prognosis, cryotherapy is reportedly to diagnose MEM, however, the therapeutic role of cryotherapy impacts on survival has not be well addressed.Cohort data on post-cryotherapy MEM patients in a university-affiliated hospital between 2007 and 2012 were evaluated. Factors that impact survival of these subjects were analyzed (...) , two had esophageal squamous cell carcinoma, and one had metastatic renal cell carcinoma. MEM were observed as follows: 15 at the trachea, 14 at the left main bronchus, 12 at the right main bronchus, 12 at the right upper lobe bronchus, five at the right intermediate bronchus, three at the right lower lobe bronchus, three at the left upper lobe bronchus, two at the left lower lobe bronchus, and one at the right middle lobe bronchus Post-cryotherapy complications included minor bleeding (n = 14

2019 BMC pulmonary medicine

54. The Effect of Cryotherapy Application on the Success Rate of Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis. (Abstract)

The Effect of Cryotherapy Application on the Success Rate of Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis. This randomized clinical trial assessed the effect of preoperative intraoral cryotherapy application on the success rate of inferior alveolar nerve blocks (IANBs) in patients with symptomatic irreversible pulpitis (SIP).One hundred four patients with SIP were randomly distributed into 2 groups: control and cryotherapy groups. In the control group (...) , patients received an IANB injection with 2% lidocaine. In the cryotherapy group, intraoral cryotherapy application was performed for 5 minutes after the IANB. Endodontic therapy was then conducted 15 minutes after the IANB injection. If the patients reported moderate or severe pain during the procedure, the IANB was defined as "unsuccessful," and a supplementary injection was administered.All patients reported profound lip numbness. The overall success rate for the IANBs was 43.3%. In the cryotherapy

2019 Journal of Endodontics Controlled trial quality: uncertain

55. Short-term cryotherapy did not substantially reduce pain and had unclear effects on physical function and quality of life in people with knee osteoarthritis: a randomised trial. Full Text available with Trip Pro

Short-term cryotherapy did not substantially reduce pain and had unclear effects on physical function and quality of life in people with knee osteoarthritis: a randomised trial. Does short-term cryotherapy improve pain, function and quality of life in people with knee osteoarthritis (OA)?Randomised controlled trial with concealed allocation, blinded assessment of some outcomes, and intention-to-treat analysis.People living in the community with knee OA.The experimental group received (...) cryotherapy, delivered as packs of crushed ice applied to the knee with mild compression. The control group received the same regimen but with sham packs filled with sand. The interventions were applied once a day for 4 consecutive days.Participants were assessed at baseline and on the day after the 4-day intervention period. The primary outcome was pain intensity according to a visual analogue scale. Secondary outcomes were baseline to post-intervention changes according to the Western Ontario

2019 Journal of physiotherapy

56. 'I'm here to save my life': a qualitative study of experiences navigating a cryotherapy referral system for human papillomavirus-positive women in western Kenya. Full Text available with Trip Pro

'I'm here to save my life': a qualitative study of experiences navigating a cryotherapy referral system for human papillomavirus-positive women in western Kenya. We sought to understand the beliefs, social norms and logistical factors that affect human papillomavirus (HPV)-positive women's uptake of cryotherapy treatment as part of a two-part cervical cancer screening strategy in rural Kenya.In-depth interviews within a parent cluster-randomised trial.Government-run county hospital in western (...) Kenya.273 of 372 (73.4%) HPV-positive women who underwent cryotherapy RESULTS: Many women feared that an HPV infection meant they would develop cancer. Almost all women reported initial fear of the treatment procedure, followed by a more positive experience than anticipated. Lacking funds for transportation to the treatment site was the most common barrier. Women felt that decentralised treatment would be the most important facilitator of greater access. Spousal encouragement and financial support

2019 BMJ open Controlled trial quality: uncertain

57. Efficacy of Oral Cryotherapy During Oxaliplatin Infusion in Preventing Oral Thermal Hyperalgesia: A Randomized Trial. Full Text available with Trip Pro

Efficacy of Oral Cryotherapy During Oxaliplatin Infusion in Preventing Oral Thermal Hyperalgesia: A Randomized Trial. Chemotherapy-induced oral thermal hyperalgesia (OTH) is a common and debilitating side effect of platinum-based anticancer agents. This study evaluated the efficacy of oral cryotherapy in preventing OTH during oxaliplatin chemotherapy infusion.Patients with gastrointestinal cancer treated with biweekly oxaliplatin (85 mg/m2 over 120 minutes) at Abramson Cancer Center (...) at the University of Pennsylvania were randomized to receive oral cryotherapy (ice chips) during oxaliplatin infusion or standard-of-care treatment. All patients completed baseline questionnaires regarding oral and peripheral symptoms and on-treatment questionnaires on day 1 of each subsequent chemotherapy cycle. Those in the treatment arm were asked to document how long they kept the ice chips in their mouths (0, <30, 30, 60, 90, or 120 minutes) and to report their discomfort associated with oral cryotherapy

2019 Journal of the National Comprehensive Cancer Network : JNCCN Controlled trial quality: uncertain

58. Exploring the Efficacy of a Safe Cryotherapy Alternative: Physiological Temperature Changes From Cold-Water Immersion Versus Prolonged Cooling of Phase-Change Material. Full Text available with Trip Pro

Exploring the Efficacy of a Safe Cryotherapy Alternative: Physiological Temperature Changes From Cold-Water Immersion Versus Prolonged Cooling of Phase-Change Material. To evaluate the effectiveness between cold-water immersion (CWI) and phase-change-material (PCM) cooling on intramuscular, core, and skin-temperature and cardiovascular responses.In a randomized, crossover design, 11 men completed 15 min of 15°C CWI to the umbilicus and 2-h recovery or 3 h of 15°C PCM covering the quadriceps

2019 International journal of sports physiology and performance Controlled trial quality: uncertain

59. Comparing the effects of shallomin lotion and cryotherapy on treating plane warts. Full Text available with Trip Pro

Comparing the effects of shallomin lotion and cryotherapy on treating plane warts. Wart is a common transferable skin disease that is caused by human papilloma virus. Choosing the best treatment method can vary based on age, therapeutic goal, complications, and wart place. Due to antibacterial effect of shallomin (hirtifolium Boiss extract) and since its effect has not been studied yet, it was compared to cryotherapy therapeutic methods for treating patients with plane warts.The present study (...) to cryotherapy, shallomin could not lead to a significant decrease in the size and number of warts.According to the results of this study, which is the first and the only investigation into the effects of shallomin on treating plane warts, it can be stated that despite of its antibacterial, antifungal, and anti-herpetic properties, shallamin cannot be a clinically effective option for treating plane warts.

2019 Journal of family medicine and primary care Controlled trial quality: uncertain

60. Cryotherapy as a Method for Relieving Symptoms of Cervical Ectopy: A Randomized Clinical Trial. Full Text available with Trip Pro

Cryotherapy as a Method for Relieving Symptoms of Cervical Ectopy: A Randomized Clinical Trial. Benign cervical ectopy (CE) may cause chronic or recurrent symptoms leading to women repeatedly being referred to gynecology clinics. We aimed to present a safe and effective method for relieving symptoms of CE.This double-blind clinical trial was conducted among 164 women with CE who complained of persistent or recurrent symptoms of cervicitis in the last six months. Patient's demographic data (...) , medical history, symptoms, and vaginal examination results were recorded. Normal co-test or Pap smear was required to enter the study. Participants were divided into two groups; the intervention group received cryotherapy and the control group underwent cryo-placebo (inserted the probe without true cryotherapy). The outcomes including improvement of symptoms and CE were monitored one, three, and six months later.The prevalence of symptoms in the two groups were not significantly different (p > 0.050

2019 Oman medical journal Controlled trial quality: uncertain

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