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21. Early-Medium-Term Outcomes of Primary Focal Cryotherapy to Treat Nonmetastatic Clinically Significant Prostate Cancer from a Prospective Multicentre Registry. (PubMed)

Early-Medium-Term Outcomes of Primary Focal Cryotherapy to Treat Nonmetastatic Clinically Significant Prostate Cancer from a Prospective Multicentre Registry. Focal cryotherapy can be used to treat patients with clinically significant nonmetastatic prostate cancer to reduce side effects.Early-medium-term cancer control and functional outcomes.A prospective registry-based case series of 122 consecutive patients undergoing focal cryotherapy between October 1, 2013, and November 30, 2016, in five (...) was 90.5% [95% confidence interval (CI) 84.2-97.3]. When stratified for the NCCN risk group, 3-yr outcomes were 84.7% (95% CI 71.4-100) in high risk and 93.3% (95% CI 86.8-100) in intermediate risk. At last follow-up, incontinence defined as any pad use was 0/69 (0%) and erectile dysfunction (defined as erections insufficient for penetration) was 5/31 (16.1%). Limitations include lack of long-term outcomes.Focal cryotherapy primarily for anterior intermediate and high-risk prostate cancer results

2019 European Urology

22. Physiological responses to partial-body cryotherapy performed during a concurrent strength and endurance session. (PubMed)

Physiological responses to partial-body cryotherapy performed during a concurrent strength and endurance session. This investigation examined the effect of partial-body cryostimulation (PBC) performed in the recovery time between a strength training and an interval running (IR) session. Nine rugby players (age, 23.7 ± 3.6 years; body mass index, 28.0 ± 2.6 kg·m-2) were randomly exposed to 2 different conditions: (i) PBC: 3 min at -160 °C, and (ii) passive recovery at 21 °C. We performed (...) , the BIA vector was restored close to normohydration status. Autonomic variables changed over time in both conditions, although the mean differences and effect sizes were greater in the PBC condition. During IR, HR was 3.5% lower after PBC, and the same result was observed for oxygen uptake (∼4.9% lower) and ventilation (∼6.5% lower). The energy cost measured after cryotherapy was ∼9.0% lower than after passive recovery. Cryotherapy enhances recovery after a single strength training session, and during

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2019 Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme

23. Cryotherapy Treatment After Unicompartmental and Total Knee Arthroplasty: A Review

Cryotherapy Treatment After Unicompartmental and Total Knee Arthroplasty: A Review Cryotherapy is widely utilized to enhance recovery after knee surgeries. However, the outcome parameters often vary between studies. Therefore, the purpose of this review is to compare (1) no cryotherapy vs cryotherapy; (2) cold pack cryotherapy vs continuous flow device cryotherapy; (3) various protocols of application of these cryotherapy methods; and (4) cost-benefit analysis in patients who had (...) unicompartmental knee arthroplasty (UKA) or total knee arthroplasty (TKA).A search for "knee" and "cryotherapy" using PubMed, EBSCO Host, and SCOPUS was performed, yielding 187 initial reports. After selecting for RCTs relevant to our study, 16 studies were included.Of the 8 studies that compared the immediate postoperative outcomes between patients who did and did not receive cryotherapy, 5 studies favored cryotherapy (2 cold packs and 3 continuous cold flow devices). Of the 6 studies comparing the use

2017 EvidenceUpdates

24. Cryotherapy in reducing pain, trismus, and facial swelling after third-molar surgery: Systematic review and meta-analysis of randomized clinical trials. (PubMed)

Cryotherapy in reducing pain, trismus, and facial swelling after third-molar surgery: Systematic review and meta-analysis of randomized clinical trials. The aim of this systematic review and meta-analysis was to evaluate the efficacy of cryotherapy in reducing pain, trismus, and facial swelling in patients undergoing third-molar surgery.The authors searched for randomized clinical trials in PubMed, Web of Science, SCOPUS, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov (...) , Google Scholar, and OpenThesis. Eligibility criteria were population: patients submitted to removal of impacted third molars; intervention and comparison: postoperative cryotherapy versus no cold therapy; and outcomes: primary outcome was postoperative pain, and secondary outcomes were facial swelling and trismus. Eligible studies must have reported at least 1 of the outcomes of interest. After extracting data and assessing quality, the authors performed the meta-analyses.The authors included 6

2019 Journal of the American Dental Association

25. Whole body cryotherapy, cold water immersion, or a placebo following resistance exercise: a case of mind over matter? (PubMed)

Whole body cryotherapy, cold water immersion, or a placebo following resistance exercise: a case of mind over matter? The use of cryotherapy as a recovery intervention is prevalent amongst athletes. Performance of high volume, heavy load resistance exercise is known to result in disturbances of muscle function, perceptual responses and blood borne parameters. Therefore, this study investigated the influence of cold water immersion (CWI), whole body cryotherapy (WBC) or a placebo (PL (...) function, and increased inflammation and efflux of intracellular proteins. Although WBC attenuated soreness at 24 h, and positively influenced peak force at 48 h compared to CWI and PL, many of the remaining outcomes were trivial, unclear or favoured the PL condition. With the exception of CRP at 24 h, neither cryotherapy intervention attenuated the inflammatory response compared to PL.There was some evidence to suggest that WBC is more effective than CWI at attenuating select perceptual and functional

2019 European journal of applied physiology

26. Effect of intracanal cryotherapy on the fracture resistance of endodontically treated teeth. (PubMed)

Effect of intracanal cryotherapy on the fracture resistance of endodontically treated teeth. The aim of this study is to evaluate the effect of intracanal cryotherapy on the fracture resistance of endodontically treated teeth.Sixty single-rooted maxillary lateral incisor teeth with single root canals were selected and randomly divided into two groups (n = 30). The specimens were immersed in distilled water, which was heated to 37 °C during the procedures. The root canals were chemomechanically (...) prepared up to the apical size of 50 and assigned to either the control group or the cryotherapy group. The specimens in the cryotherapy group were irrigated with 20 mL sterile cold (2.5 °C) saline solution, which was delivered with an EndoVac system for 5 min, whereas the specimens in the control group received a sterile saline solution at room temperature. The fracture resistance of the specimens was then tested with a universal testing machine. The data was analyzed using the independent sample t

2019 Acta odontologica Scandinavica

27. Whole-body cryotherapy (-110 °C) following high-intensity intermittent exercise does not alter hormonal, inflammatory or muscle damage biomarkers in trained males. (PubMed)

Whole-body cryotherapy (-110 °C) following high-intensity intermittent exercise does not alter hormonal, inflammatory or muscle damage biomarkers in trained males. This study examined the acute effects of a single session of Whole-body Cryotherapy (WBC) following severe intermittent running exercise on biomarkers of inflammation, muscle damage and stress.Endurance-trained males (n = 11) were tested twice using a within-participant, balanced cross-over design that consisted of 5 × 5 min

2019 Cytokine

28. Comparison of cold water immersion, whole body cryotherapy and a placebo control for recovery following a marathon.

Comparison of cold water immersion, whole body cryotherapy and a placebo control for recovery following a marathon. Comparison of cold water immersion, whole body cryotherapy and a placebo control for recovery following a marathon. – Less Is More Search for: Simpler & Better Medicine Menu / Summary: For athletes participating in a marathon, post-race cold-water immersion may provide superior recovery of muscle function and reduced perceptions of soreness compared to whole-body cryotherapy

2018 Less Is More Blog

29. Factors affecting survival in patients with endobronchial malignant mass after flexible Bronchoscopic cryotherapy: a cohort study. (PubMed)

Factors affecting survival in patients with endobronchial malignant mass after flexible Bronchoscopic cryotherapy: a cohort study. Malignant endobronchial mass (MEM) has poor prognosis, cryotherapy is reportedly to diagnose MEM, however, the therapeutic role of cryotherapy impacts on survival has not be well addressed.Cohort data on post-cryotherapy MEM patients in a university-affiliated hospital between 2007 and 2012 were evaluated. Factors that impact survival of these subjects were analyzed (...) , two had esophageal squamous cell carcinoma, and one had metastatic renal cell carcinoma. MEM were observed as follows: 15 at the trachea, 14 at the left main bronchus, 12 at the right main bronchus, 12 at the right upper lobe bronchus, five at the right intermediate bronchus, three at the right lower lobe bronchus, three at the left upper lobe bronchus, two at the left lower lobe bronchus, and one at the right middle lobe bronchus Post-cryotherapy complications included minor bleeding (n = 14

2019 BMC pulmonary medicine

30. The Effect of Cryotherapy Application on the Success Rate of Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis. (PubMed)

The Effect of Cryotherapy Application on the Success Rate of Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis. This randomized clinical trial assessed the effect of preoperative intraoral cryotherapy application on the success rate of inferior alveolar nerve blocks (IANBs) in patients with symptomatic irreversible pulpitis (SIP).One hundred four patients with SIP were randomly distributed into 2 groups: control and cryotherapy groups. In the control group (...) , patients received an IANB injection with 2% lidocaine. In the cryotherapy group, intraoral cryotherapy application was performed for 5 minutes after the IANB. Endodontic therapy was then conducted 15 minutes after the IANB injection. If the patients reported moderate or severe pain during the procedure, the IANB was defined as "unsuccessful," and a supplementary injection was administered.All patients reported profound lip numbness. The overall success rate for the IANBs was 43.3%. In the cryotherapy

2019 Journal of Endodontics

31. 'I'm here to save my life': a qualitative study of experiences navigating a cryotherapy referral system for human papillomavirus-positive women in western Kenya. (PubMed)

'I'm here to save my life': a qualitative study of experiences navigating a cryotherapy referral system for human papillomavirus-positive women in western Kenya. We sought to understand the beliefs, social norms and logistical factors that affect human papillomavirus (HPV)-positive women's uptake of cryotherapy treatment as part of a two-part cervical cancer screening strategy in rural Kenya.In-depth interviews within a parent cluster-randomised trial.Government-run county hospital in western (...) Kenya.273 of 372 (73.4%) HPV-positive women who underwent cryotherapy RESULTS: Many women feared that an HPV infection meant they would develop cancer. Almost all women reported initial fear of the treatment procedure, followed by a more positive experience than anticipated. Lacking funds for transportation to the treatment site was the most common barrier. Women felt that decentralised treatment would be the most important facilitator of greater access. Spousal encouragement and financial support

2019 BMJ open

32. Short-term cryotherapy did not substantially reduce pain and had unclear effects on physical function and quality of life in people with knee osteoarthritis: a randomised trial. (PubMed)

Short-term cryotherapy did not substantially reduce pain and had unclear effects on physical function and quality of life in people with knee osteoarthritis: a randomised trial. Does short-term cryotherapy improve pain, function and quality of life in people with knee osteoarthritis (OA)?Randomised controlled trial with concealed allocation, blinded assessment of some outcomes, and intention-to-treat analysis.People living in the community with knee OA.The experimental group received (...) cryotherapy, delivered as packs of crushed ice applied to the knee with mild compression. The control group received the same regimen but with sham packs filled with sand. The interventions were applied once a day for 4 consecutive days.Participants were assessed at baseline and on the day after the 4-day intervention period. The primary outcome was pain intensity according to a visual analogue scale. Secondary outcomes were baseline to post-intervention changes according to the Western Ontario

2019 Journal of physiotherapy

33. Limited Quality Evidence Suggests that Application of Cryotherapy May Be Helpful in Reducing Postoperative Pain in Root Canal Therapy in Patients With Symptomatic Apical Periodontitis. (PubMed)

Limited Quality Evidence Suggests that Application of Cryotherapy May Be Helpful in Reducing Postoperative Pain in Root Canal Therapy in Patients With Symptomatic Apical Periodontitis. Effects of Various Cryotherapy Applications on Postoperative Pain in Molar Teeth with Symptomatic Apical Periodontitis: A Preliminary Randomized Prospective Clinical Trial. Gundogdu EC, Arslan H. J Endod 2018:44(3):349-54.Not mentioned.Randomized controlled trial with parallel design.Copyright © 2019 Elsevier Inc

2019 Journal of Evidence Based Dental Practice

34. Multifaceted Comparison of Two Cryotherapy Devices Used After Total Knee Arthroplasty: Cryotherapy Device Comparison. (PubMed)

Multifaceted Comparison of Two Cryotherapy Devices Used After Total Knee Arthroplasty: Cryotherapy Device Comparison. Some form of cryotherapy used after total knee arthroplasty is commonplace. However, various factors determine the specific device deployed.This study aimed to answer the following questions:: A group of 100 patients undergoing primary total knee arthroplasty by a single surgeon were enrolled in an institutional review board-approved, prospective study and randomized to receive (...) either a circulating cold water or ice/gel pack cryotherapy device postoperatively. Demographic, pain, swelling, blood loss, range of motion, compliance, satisfaction, and adverse event outcomes were recorded until 6 weeks after surgery. Hospital staff satisfaction and economic variables were examined.The ice/gel pack cryotherapy wrap was noninferior to the cold water cryotherapy device for any patient outcome measured. Average pain level at 6 weeks postoperative was significantly less in the ice/gel

2018 Orthopedic nursing

35. Cryotherapy for liver metastases. (PubMed)

Cryotherapy for liver metastases. Primary liver tumours and liver metastases from colorectal carcinoma are the two most common malignant tumours to affect the liver. The liver is second only to the lymph nodes as the most common site for metastatic disease. More than half of the patients with metastatic liver disease will die from metastatic complications. In cryoablation, liquid nitrogen or argon gas is delivered to the liver tumour, guided by ultrasound using a specially designed probe. Ice (...) crystal formation during the rapid freezing process causes destruction of cellular structure and kills the tumour cells.To study the beneficial and harmful effects of cryotherapy compared with no intervention, other ablation methods, or systemic treatments in patients with liver metastases.We searched the Cochrane Hepato-Biliary Group Controlled Trials Register, The Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library, MEDLINE, EMBASE, Science Citation Index Expanded

2013 Cochrane

36. Cryotherapy systems for wart removal: a review of the clinical effectiveness, cost-effectiveness, and guidelines

Cryotherapy systems for wart removal: a review of the clinical effectiveness, cost-effectiveness, and guidelines Cryotherapy systems for wart removal: a review of the clinical effectiveness, cost-effectiveness, and guidelines Cryotherapy systems for wart removal: a review of the clinical effectiveness, cost-effectiveness, and guidelines CADTH Citation CADTH. Cryotherapy systems for wart removal: a review of the clinical effectiveness, cost-effectiveness, and guidelines. Ottawa: Canadian Agency (...) for Drugs and Technologies in Health (CADTH). Rapid Response. 2014 Authors' conclusions Limited evidence suggested that cryotherapy with liquid nitrogen using a melamine foam sponge (MFS) applicator was superior to cotton wool bud (CWB) applicators for reducing wart size after one treatment, with a lower mean number of treatments at complete remission and fewer adverse events, though the generalizability of these findings to a Canadian context is unclear. There was no evidence identified for the cost

2014 Health Technology Assessment (HTA) Database.

37. EVerT: cryotherapy versus salicylic acid for the treatment of verrucae - a randomised controlled trial

EVerT: cryotherapy versus salicylic acid for the treatment of verrucae - a randomised controlled trial EVerT: cryotherapy versus salicylic acid for the treatment of verrucae - a randomised controlled trial Journals Library An error has occurred in processing the XML document An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website (...) search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} The report finds no evidence of a difference in clearance rates of verrucae between salicylic acid treatment and cryotherapy; however, cryotherapy was associated with higher mean costs per patient healed than salicylic acid. {{author}} {{($index An error has occurred in processing the XML document An error has occurred in processing the XML document

2011 NIHR HTA programme

38. Comparison of different cryotherapy recovery methods in elite junior cyclists (PubMed)

Comparison of different cryotherapy recovery methods in elite junior cyclists Cold water immersion (CWI) and active recovery treatment (ACT) are commonly used recovery treatments for athletes between exercise bouts, but they are sometimes limited by space and availability of equipment in training and competition venues. Therefore, the purpose of this study was to determine whether cold compression therapy (CCT) would provide the same effect as CWI and ACT as an alternative option in a hot

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2016 Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology

39. Cryotherapy to reduce pain and swelling after facial surgery

Cryotherapy to reduce pain and swelling after facial surgery Cryotherapy to reduce pain and swelling after facial surgery - National Elf Service Search National Elf Service Search National Elf Service » » » » Cryotherapy to reduce pain and swelling after facial surgery Dec 21 2016 Posted by Facial cooling (cryotherapy) is a traditional approach to minimising pain, swelling and discomfort following trauma or surgery. However, there are concerns that it may affect microvascular blood flow (...) and lymph drainage causing damage. Contoured facial masks have been developed to channel a current of cool, sterile water adjacent to the skin to provide regulated cryotherapy. Although studies have provided conflicting evidence of it efficacy. The aim of this review to assess the evidence for the use of perioperative cryotherapy after facial surgery. Methods Searches were conducted in Medline/PubMed, Embase, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials

2016 The Dental Elf

40. Oral cryotherapy reduces oral mucositis in patients receiving 5FU-based treatment for solid cancers

Oral cryotherapy reduces oral mucositis in patients receiving 5FU-based treatment for solid cancers Oral cryotherapy reduces oral mucositis Search National Elf Service Search National Elf Service » » » » Oral cryotherapy reduces oral mucositis in patients receiving 5FU-based treatment for solid cancers Jan 11 2016 Posted by Around 75% of patients receiving chemotherapy, radiotherapy of the head and neck, or targeted therapy suffer from oral mucositis. Ulceration is of varying severity but can (...) lead to difficulties with eating, swallowing, and talking leading to increase need for pain relief and nutritional support. It also has a negative effect on quality of life. The aim of this Cochrane review was to assess the effects of oral cryotherapy for preventing oral mucositis in patients with cancer who are receiving treatment. Methods Searches were conducted in the Cochrane Oral Health Group Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase

2016 The Dental Elf

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