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Cryotherapy

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181. Cryotherapy: Are we freezing the benefits of exercise? (PubMed)

Cryotherapy: Are we freezing the benefits of exercise? 28944266 2018 11 13 2332-8940 4 3 2017 Temperature (Austin, Tex.) Temperature (Austin) Cryotherapy: Are we freezing the benefits of exercise? 211-213 10.1080/23328940.2017.1304194 Peake Jonathan M JM Tissue Repair and Translational Physiology Research Group School of Biomedical Sciences and Institute of Health and Biomedical Innovation Queensland University of Technology, Brisbane, AustraliaCentre of Excellence for Applied Sport Science

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2017 Temperature: Multidisciplinary Biomedical Journal

182. Efficacy of Punch Reduction Prior to Cryotherapy in Patients with Viral Warts: A Case-Control Study in a Single Tertiary Center (PubMed)

Efficacy of Punch Reduction Prior to Cryotherapy in Patients with Viral Warts: A Case-Control Study in a Single Tertiary Center Cutaneous warts are a common complaint to visit dermatologic clinic and its course is variable, ranging from spontaneous resolution to a chronic condition refractory to treatment.To evaluate the efficacy and safety of punch biopsy for cutaneous warts.Thirty-nine patients who received punch biopsy for warts were reviewed through charts and photos. Among them, 15 were (...) matched with cryotherapy-only controls in terms of size and location of the wart. We compared the number and cost of treatments between the two groups.Eleven of the total 39 patients were treated with cryotherapy in addition to punch biopsy and the average number of treatments was 4.1±3.3 (mean±standard deviation). In a case-control study, the ratio value of cost was 2.9±3.6 in the experimental group and was 5.9±4.1 in controls (p<0.05).Punch biopsies can decrease the number and cost of treatment

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2017 Annals of dermatology

183. Intralesional cryotherapy for hypertrophic scars and keloids: a review (PubMed)

Intralesional cryotherapy for hypertrophic scars and keloids: a review Hypertrophic and keloid scarring remain notoriously troublesome for patients to tolerate and frustratingly difficult for clinicians to treat. Many different treatment modalities exist, signifying the failure of any method to achieve consistently excellent results. Intralesional cryotherapy is a relatively recent development that uses a double lumen needle, placed through the core of a keloid or hypertrophic scar, to deliver (...) nitrogen vapour, which freezes the scar from its core, outwards.This article provides a comprehensive review of the literature on intralesional cryotherapy for hypertrophic scars and keloids. A systematic review or meta-analysis was not possible, since the existing articles did not permit this.A search of English language, peer-reviewed literature was carried out. The evidence base was found to be low (level 4). In addition, much of the published evidence comes from a very few groups. Despite

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2017 Scars, Burns & Healing

184. Postoperative complications with cryotherapy in bone tumors (PubMed)

Postoperative complications with cryotherapy in bone tumors The technique of cryosurgery has been used to control local recurrence in a variety of benign and malignant bone tumors. Early studies revealed significant complication rates (25%) that included fracture, infection, and soft tissue injury. Our method of cryosurgery has yielded excellent tumor control with improved complication rates. The objective of this study is to determine the characteristics of postoperative complications after (...) pouring liquid nitrogen into curettaged bone defects, and to review our current indications and surgical technique in bone tumor management. We reviewed charts in over 200 patients who received cryoablation for bone tumors from 1994 to 2015. Imaging studies were evaluated in all patients diagnosed with a complication. All patients receiving cryotherapy had soft tissue management intraoperatively that included warm saline directed to the structures. Liquid nitrogen was poured into the bone defect

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2017 Journal of bone oncology

185. Whole-Body Cryotherapy in Athletes: From Therapy to Stimulation. An Updated Review of the Literature (PubMed)

Whole-Body Cryotherapy in Athletes: From Therapy to Stimulation. An Updated Review of the Literature Nowadays, whole-body cryotherapy is a medical physical treatment widely used in sports medicine. Recovery from injuries (e.g., trauma, overuse) and after-season recovery are the main purposes for application. However, the most recent studies confirmed the anti-inflammatory, anti-analgesic, and anti-oxidant effects of this therapy by highlighting the underlying physiological responses (...) . In addition to its therapeutic effects, whole-body cryotherapy has been demonstrated to be a preventive strategy against the deleterious effects of exercise-induced inflammation and soreness. Novel findings have stressed the importance of fat mass on cooling effectiveness and of the starting fitness level on the final result. Exposure to the cryotherapy somehow mimics exercise, since it affects myokines expression in an exercise-like fashion, thus opening another possible window on the therapeutic

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2017 Frontiers in physiology

186. Large Bowel Obstruction following Endoscopic Spray Cryotherapy for Palliation of Rectal Cancer Bleeding (PubMed)

Large Bowel Obstruction following Endoscopic Spray Cryotherapy for Palliation of Rectal Cancer Bleeding We report a unique case of a 79-year-old woman with metastatic rectal cancer who developed bowel obstruction following endoscopic cryotherapy with liquid nitrogen for palliation of bleeding in the rectum. She developed abdominal distention and pain following the procedure. Computed tomography of the abdomen revealed a paraumbilical hernia containing a segment of transverse colon resulting (...) in partial bowel obstruction. It appears that the recurrent freeze-thaw cycles with poor decompression of the colon despite active venting suction during cryotherapy may have resulted in bowel distention and collapse, causing conformational changes resulting in partial bowel obstruction due to a paraumbilical hernia.

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2017 ACG case reports journal

187. Cryotherapy as a conservative treatment modality for gingival enlargement in a patient with Sturge-Weber Syndrome (PubMed)

Cryotherapy as a conservative treatment modality for gingival enlargement in a patient with Sturge-Weber Syndrome This case report describes a case of Sturge-Weber syndrome reported for unilateral gingival enlargement and bleeding from gingiva in maxillary left region. Initial treatment in the form of scaling and root planing was done but recurrence was observed after one year of follow up. Instead of performing conventional surgery, an alternative conservative treatment was planned in the form (...) of cryotherapy with the help of closed nitrous oxide probe. Seeing the satisfactory results obtained, cryotherapy can be suggested as an atraumatic, bloodless and effective chair side procedure for treating vascular gingival enlargement.

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2017 Intractable & rare diseases research

188. Local cryotherapy minimally impacts the metabolome and transcriptome of human skeletal muscle (PubMed)

Local cryotherapy minimally impacts the metabolome and transcriptome of human skeletal muscle Cryotherapy is commonly used in the treatment of skeletal muscle injuries. However, the data to support the use of cryotherapy is inconclusive, and the biochemical etiology of cryotherapy in human skeletal muscle remains largely unknown. We therefore sought to determine how a clinically-relevant dose of cryotherapy would impact the transcriptome and metabolome of skeletal muscle. Eight healthy male (...) subjects (age 24.7 ± 4.5 years, BMI 22.2 ± 1.6) received a 15 minute bout of local cryotherapy, delivered via ice cup massage over the anterolateral thigh. This resulted in an 85% decrease in skin temperature and a predicted 27% reduction in intramuscular temperature. The contralateral side served as a non-treated control. Two hours after cryotherapy, muscle biopsies were obtained to analyze changes in the transcriptome, metabolome, and activation of p38 MAPK, ERK1/2, Akt, and p70S6K proteins

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2017 Scientific reports

189. Difference Between Cryotherapy and Follow Up Low Grade Squamous Lesion of Cervix Uteri (PubMed)

Difference Between Cryotherapy and Follow Up Low Grade Squamous Lesion of Cervix Uteri Cervical cancer can be successfully prevented by effective treatment.Analyse of success of cryotherapy in LSIL and ASCUS.In retrospective study between January 2016 to March 2017, 3244 PAP test were analysed. 257 patients who had been diagnosed with LSIL and ASCUS from PAP smear were divided in two groups: women who had HPV positive, colposcopic positive and cytologic finding of LSIL or ASCUS treathed (...) with cryotherapy and women with LSIL, ASCUS and negative colposcopy. χ2 test was used for statistical analysis of data.Analysis of 3244 PAP smears showed negative for intraepithelial lesion or malignancy (NILM) in 90,10% (N-2923), and abnormal in 9,8% (N-321) of women. ASCUS was found in 4,8% (N-156) and ASC-H in 0,2% (N-6), LSIL in 3,1% (N-101), HSIL in 0,64% (N-21). The average age of patients with ASCUS lesion was 41 ± 12 years. After cryotherapy, HSIL had progression in 1,5% (N-1), persistence in 6,3% (N-4

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2017 Medical Archives

190. Irreversible Electroporation for Prostate Cancer as Salvage Treatment Following Prior Radiation and Cryotherapy (PubMed)

Irreversible Electroporation for Prostate Cancer as Salvage Treatment Following Prior Radiation and Cryotherapy Salvage treatment options after localized primary treatment failure of prostate cancer are limited and associated with risk for serious complications. We report on the management details of a 57-year-old African American man treated with partial-gland ablation using irreversible electroporation following local recurrence after brachytherapy and prior salvage cryoablation. Therapeutic

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2017 Reviews in urology

191. Efficacy and safety of liquid nitrogen cryotherapy for treatment of Barrett’s esophagus (PubMed)

Efficacy and safety of liquid nitrogen cryotherapy for treatment of Barrett’s esophagus To evaluate the efficacy and safety of liquid nitrogen cryotherapy as a primary or rescue treatment for BE, with and without dysplasia, or intramucosal adenocarcinoma (IMC).This was a retrospective, single-center study carried out in a tertiary care center including 45 patients with BE who was treatment-naïve or who had persistent intestinal metaplasia (IM), dysplasia, or IMC despite prior therapy (...) . Barrett's mucosa was resected via EMR when clinically appropriate, then patients underwent cryotherapy until eradication or until deemed to have failed treatment. Surveillance biopsies were taken at standard intervals.From 2010 through 2014, 33 patients were studied regarding the efficacy of cryotherapy. Overall, 29 patients (88%) responded to cryotherapy, with 84% having complete regression of all dysplasia and cancer. Complete eradication of cancer and dysplasia was seen in 75% of subjects with IMC

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2017 World journal of gastrointestinal endoscopy

192. Interleukin-10 and Interferon-γ Levels in Patients with Cutaneous Leishmaniasis Treated with Cryotherapy (PubMed)

Interleukin-10 and Interferon-γ Levels in Patients with Cutaneous Leishmaniasis Treated with Cryotherapy Pentavalent antimonials, as the 1st choice for the treatment of cutaneous leishmaniasis (CL), have various side effects. Also, there are some reports of drug resistance. Due to its safety, cryotherapy can be a good alternative or complementary treatment in CL. The aim of this study was to explore the possible systemic immunological mechanisms of cryotherapy besides its local effects (...) in the treatment of CL. Twenty patients with CL were selected. The disease was confirmed via a direct smear. A venous blood sample was collected to determine IL-10 and IFN-γ levels before starting cryotherapy. Then, 1 week after 8 sessions of cryotherapy were completed (i.e., 63 d), a 2nd venous sample was taken in order to compare the results with the pretreatment levels of these cytokines using the ELISA method. Cryotherapy resulted in no change in the levels of IL-10 and significantly increased the IFN-γ

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2017 Iranian journal of medical sciences

193. Effect of Whole-Body Cryotherapy on Antioxidant Systems in Experimental Rat Model (PubMed)

Effect of Whole-Body Cryotherapy on Antioxidant Systems in Experimental Rat Model The purpose of this study was to verify the effect of whole-body cryotherapy (WBC) in rats on their antioxidant systems, lipid peroxidation products, and their total oxidative status at different exposure times and temperatures.Antioxidants in serum, plasma, liver, and erythrocytes were evaluated in two study groups following 1 min of exposure to -60°C and -90°C, for 5 and 10 consecutive days.WBC increased (...) , and increase of erythrocyte malondialdehyde concentration after 5 days, -90°C.To the best of our knowledge, this is the first research showing the effect of WBC in rats at different exposure times and temperatures. The effect of cryotherapy on enzymatic and nonenzymatic antioxidant systems was observed in the serum of animals exposed to a temperature of -60°C in comparison to control.

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2017 Oxidative medicine and cellular longevity

194. Cost-effectiveness of cervical cancer screening and preventative cryotherapy at an HIV treatment clinic in Kenya (PubMed)

Cost-effectiveness of cervical cancer screening and preventative cryotherapy at an HIV treatment clinic in Kenya This study evaluated the potential cost-effectiveness of cervical cancer screening in HIV treatment clinics in Nairobi, Kenya.A Markov model was used to project health outcomes and costs of cervical cancer screening and cryotherapy at an HIV clinic in Kenya using cryotherapy without screening, visual inspection with acetic acid (VIA), Papanicolaou smear (Pap), and testing for human (...) papillomavirus (HPV). Direct and indirect medical and non-medical costs were examined from societal and clinic perspectives.Costs of cryotherapy, VIA, Pap, and HPV for women with CD4 200-500 cells/mL were $99, $196, $219, and $223 from a societal perspective and $19, $94, $124, and $113 from a clinic perspective, with 17.3, 17.1, 17.1, and 17.1 years of life expectancy, respectively. Women at higher CD4 counts (>500 cells/mL) given cryotherapy VIA, Pap, and HPV resulted in better life expectancies (19.9

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2017 Cost effectiveness and resource allocation : C/E

195. Profuse and acute hemorrhagic gastroesophageal injury after cryotherapy in a cardiac surgery patient (PubMed)

Profuse and acute hemorrhagic gastroesophageal injury after cryotherapy in a cardiac surgery patient Upper gastrointestinal injury associated with cryoablation and under placement of transesophageal echocardiography (TEE) during cardiac surgery is a rare complication but potentially fatal. During the cryoablation for the treatment of atrial fibrillation, delivered cryoenergy can adversely affect the esophagus, resulting in gastroesophageal ulceration. The TEE probe itself also can induce

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2017 Journal of thoracic disease

196. Therapeutic Effect of Superficial Cryotherapy on Alopecia Areata: A Prospective, Split-scalp Study in Patients with Multiple Alopecia Patches (PubMed)

Therapeutic Effect of Superficial Cryotherapy on Alopecia Areata: A Prospective, Split-scalp Study in Patients with Multiple Alopecia Patches Alopecia areata (AA) affects anagen hair follicles resulting in non-scarring hair loss. Since its introduction, superficial cryotherapy has been used as one of the meaningful treatment modalities for AA.The purpose of this study is to clarify the therapeutic efficacy and safety of superficial cryotherapy for treatment of AA.In 19 patients with multiple (...) bilateral AA patches on their scalp, superficial cryotherapy was performed on the right side, every 2 weeks. Prednicarbate 0.25% solution was applied twice a day to both the treated and the control sides. Clinical improvement was estimated using the Severity of Alopecia Tool (SALT) score by 3 different dermatologists, along with the changes in terminal and vellus hair count and hair thickness analyzed by phototrichogram.After 4 months of treatment, mean terminal hair count on the right scalp was 1.6

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2017 Annals of dermatology

197. Unilateral Quadriceps Strengthening With Disinhibitory Cryotherapy and Quadriceps Symmetry After Anterior Cruciate Ligament Reconstruction (PubMed)

Unilateral Quadriceps Strengthening With Disinhibitory Cryotherapy and Quadriceps Symmetry After Anterior Cruciate Ligament Reconstruction   The effect of unilateral cryotherapy-facilitated rehabilitation exercise on involved-limb quadriceps function and limb symmetry in individuals with quadriceps dysfunction after anterior cruciate ligament reconstruction (ACLR) remains unclear.  To measure the effect of a 2-week unilateral cryotherapy-facilitated quadriceps-strengthening program on knee (...) .  Participants with ACLR completed a 2-week unilateral cryotherapy-facilitated quadriceps-strengthening intervention.  Bilateral normalized knee-extension maximal voluntary isometric contraction (MVIC) torque (Nm/kg) and quadriceps CAR (%) were assessed preintervention and postintervention. Limb symmetry index (LSI) was calculated at preintervention and postintervention testing. Preintervention between-groups differences in unilateral quadriceps function and LSI were evaluated using independent-samples t

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2017 Journal of athletic training

198. Cryotherapy Treatment After Unicompartmental and Total Knee Arthroplasty: A Review. (PubMed)

Cryotherapy Treatment After Unicompartmental and Total Knee Arthroplasty: A Review. Cryotherapy is widely utilized to enhance recovery after knee surgeries. However, the outcome parameters often vary between studies. Therefore, the purpose of this review is to compare (1) no cryotherapy vs cryotherapy; (2) cold pack cryotherapy vs continuous flow device cryotherapy; (3) various protocols of application of these cryotherapy methods; and (4) cost-benefit analysis in patients who had (...) unicompartmental knee arthroplasty (UKA) or total knee arthroplasty (TKA).A search for "knee" and "cryotherapy" using PubMed, EBSCO Host, and SCOPUS was performed, yielding 187 initial reports. After selecting for RCTs relevant to our study, 16 studies were included.Of the 8 studies that compared the immediate postoperative outcomes between patients who did and did not receive cryotherapy, 5 studies favored cryotherapy (2 cold packs and 3 continuous cold flow devices). Of the 6 studies comparing the use

2017 Journal of Arthroplasty

199. Oral cryotherapy for oral mucositis in patients receiving chemotherapy

Oral cryotherapy for oral mucositis in patients receiving chemotherapy Patient Services/Oral Mucositis/Use of Oral Cryotherapy/BESt 171 Best Evidence Statement (BESt) Copyright © 2013 Cincinnati Children's Hospital Medical Center; all rights reserved Page 1 of 5 Date: June 20, 2013 Title: Using oral cryotherapy to prevent oral mucositis in patients receiving chemotherapy Clinical Question: P (Population/Problem) Among patients of all ages receiving chemotherapy I (Intervention) does oral (...) cryotherapy* C (Comparison) compared to no intervention O (Outcome) reduce the severity of, or prevent, chemotherapy-induced oral mucositis? Definitions for terms marked with * may be found in the Supporting Information section. Target Population for the Recommendation: Inclusion: Oncology or bone marrow transplant patients being treated with bolus 5-FU, melphalan, or BEAC (high dose carmustine, etoposide, cytarabine, and cyclophosphamide) chemotherapy regimens Exclusion: Patients with malignancies

2013 Cincinnati Children's Hospital Medical Center

200. Whole-Body Cryotherapy in Sports Medicine. (PubMed)

Whole-Body Cryotherapy in Sports Medicine. Cryotherapy has gained popularity among athletes across many sports. The main goals of cryotherapy, and specifically whole-body cryotherapy, are for injury prevention and counteracting negative inflammatory symptoms following athletic performance in hopes of improving recovery.

2019 Current Sports Medicine Reports

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