How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

2,513 results for


Latest & greatest

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

102. British Association of Dermatologists and British photodermatology Group guidelines for topical photodynamic therapy

to limitations in the ability to compare studies. Lesion preparation is a routinely performed aspect of deliv- ering topical PDT regardless of which product is being used. The gentle removal of crusts and scale with a scalpel or curette is commonly performed without causing pain and does not require local anaesthesia. The treatment area can be degreased with 70% isopropyl alcohol (especially for Ameluz). Other additional preparation techniques or combination treatment approaches reported include

2019 British Association of Dermatologists

103. Guidelines for topical photodynamic therapy (PDT)

. If necessary, any loose scale or crusts are removed first. A dressing is then applied over the cream and you will be asked to return in about 3 hours. This wait is to allow the photosensitiser to be absorbed and to convert into the active chemical by the skin. The cream is then wiped off and the area cleaned. A bright coloured light is then shone onto the treatment area for approximately 10 to 45 minutes (the precise time will be determined by your doctor or nurse depending on the light source). After

2019 British Association of Dermatologists

104. Cutaneous melanoma

into types on the basis of clinical features and pathology. 4.1.1 SUPERFICIAL SPREADING MALIGNANT MELANOMA Superficial spreading malignant melanoma (SSMM) is the most frequently encountered type of melanoma; characteristically an asymmetrical pigmented lesion with variable pigmentation and sometimes an irregular outline. Patients may have noted growth, a change in sensation and/or colour, crusting, bleeding or inflammation of the lesion. The duration of the symptoms varies from a few months to several (...) of the features in the ABCDE system, is an indication for referral. The presence of minor features should increase suspicion. It is accepted that some melanomas will have no major features. Table 3: The 7 -point checklist lesion system Major features Minor features • change in size of lesion • inflammation • irregular pigmentation • itch/altered sensation • irregular border • lesion larger than others • oozing/crusting of lesion Table 4: The ABCDE lesion system A Geometrical Asymmetry in two axes B Irregular

2017 SIGN

105. Blepharitis

Blepharitis Blepharitis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Blepharitis Last reviewed: February 2019 Last updated: October 2018 Summary Significant cause of discomfort, causing foreign body sensation, burning, itching, and crusting around eyelashes. Typical findings include lid erythema, collarettes around eyelashes, and capped meibomian glands. In severe cases, corneal changes, including (...) . It typically occurs bilaterally. Disease is usually chronic with intermittent exacerbations. History and exam burning sensation itching sensation foreign body sensation crusting of eyelids dry eye lid erythema, telangiectasias collarettes around lashes capped meibomian glands conjunctival hyperaemia unstable tear film with rapid tear break-up time chalazion scalp changes photophobia facial telangiectasias, erythema, pustules, papules depigmentation of lashes trichiasis madarosis lid margin thickening

2017 BMJ Best Practice

106. Granuloma annulare

-coloured, pink, or brown macules or small papules soft-tissue nodules perforating papules, crusting or ulcerated lesions erythematous patches diabetes mellitus haematological malignancy herpes zoster HIV hepatitis hyperlipidaemia thyroid disease medications Diagnostic investigations clinical diagnosis skin biopsy fasting blood sugar thyroid function tests lipid screening hepatitis screen HIV testing Treatment algorithm ACUTE Contributors Authors Assistant Professor Dermatology and Internal Medicine

2017 BMJ Best Practice

107. Angular cheilitis

Angular cheilitis Angular cheilitis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Angular cheilitis Last reviewed: February 2019 Last updated: December 2017 Summary Inflammation of the angles of the mouth, characterised by fissures, scaling, erythema, and crusting. Aetiology is multi-factorial and includes mechanical factors, infectious agents, nutritional deficiencies, or inflammatory dermatological conditions (...) . Diagnosis is made clinically; however, laboratory tests help to identify aetiology. Successful therapy is based on identifying and correcting each and all factors of this multi-factorial condition. Definition Angular cheilitis is inflammation of the angles of the mouth, characterised by fissures, scaling, erythema, and crusting. Skinner N, Junker JA, Flake D, et al. Clinical inquiries: what is angular cheilitis and how is it treated? J Fam Pract. 2005 May;54(5):470-1.

2017 BMJ Best Practice

109. CRACKCast E191 – Weapons of Mass Destruction

and pharyngeal mucosa. A maculopapular rash soon appears, which becomes vesicular and finally pustular. In contrast to chickenpox, the rash first appears on the face and forearms, later spreading to the legs and trunk. All the lesions in any one area of the body are at the same stage. During the next 8 to 14 days, the pustules crust over and separate from the skin, leaving pitted scars. Highly recommend this resource from the CDC: [5] How are nerve agents treated (3 drugs)? Unlike biological WMD

2018 CandiEM

110. Herpes Zoster Ophthalmicus (HZO)

appears a day to a week later General malaise, headache, fever Signs Skin features unilateral painful, red, vesicular rash on the forehead and upper eyelid, progressing to crusting after 2-3 weeks; resolution often involves scarring periorbital oedema (may close the eyelids and spread to opposite side) lymphadenopathy (swollen regional lymph nodes) lesion at the side of the tip of the nose (Hutchinson’s sign) indicates three times the usual risk of ocular complications, but these may also occur in one

2018 College of Optometrists

111. Atopic Keratoconjunctivitis (AKC)

, usually bilateral Blurred vision, photophobia White stringy mucoid discharge Onset of ocular symptoms may occur several years after onset of atopy Symptoms usually year-round, with exacerbations Signs Eyelids may be thickened, crusted and fissured Associated chronic staphylococcal blepharitis Tarsal conjunctiva: giant papillary hypertrophy, subepithelial scarring and shrinkage Entire conjunctiva hyperaemic Limbal inflammation Corneal involvement is common and may be sight-threatening: beginning

2018 College of Optometrists

112. Conjunctivitis (bacterial)

to Clinical Management Guideline on )] or sinusitis diabetes (or other disease compromising the immune system) steroids (systemic or topical, compromising ocular resistance to infection) blepharitis (or other chronic ocular inflammation) Symptoms Acute onset of: redness discomfort, usually described as burning or grittiness discharge (may cause temporary blurring of vision) crusting of lids (often stuck together after sleep and may have to be bathed open) Usually bilateral – one eye may be affected before (...) the other (by one or two days) Signs lid crusting purulent or mucopurulent discharge conjunctival hyperaemia – maximal in fornices tarsal conjunctiva may show mild papillary reaction cornea: usually no involvement (occasionally punctate epitheliopathy – mainly in lower third of cornea). If cornea significantly involved, consider possibility of gonococcal infection pre-auricular lymphadenopathy: usually absent Differential diagnosis Other forms of conjunctivitis epidemic keratoconjunctivitis (e.g

2018 College of Optometrists

115. Guidelines of care for the management of cutaneous squamous cell carcinoma

measurement should exclude parakeratosis or scale/crust and should be made from base of the ulcer is present. If clinical evaluation of incisional biopsy suggests that microstaging is inadequate, consider narrow-margin excisional biopsy. Table IV Recommendations for grading and staging of cSCC Stratification of localized SCCs using the NCCN guideline framework is recommended for clinical practice. Clinicians should refer to the BWH tumor classification system to obtain the most accurate prognostication

Full Text available with Trip Pro

2018 American Academy of Dermatology

119. CRACKCast E120 – Dermatologic presentations

Thickened area of keratinised epithelium Crust Dried area of plasma proteins, resulting from inflammation Fissure Deep cracks in skin surfaces, extending into dermis Erosion Disruption of surface epithelium, usually linear, traumatic Ulcer Deep erosion extending into dermis Scar Dense collection of collage, a result of healing after trauma or procedures Excoriation Linear erosions typically secondary to scratching or rubbing Infections Bacterial, viral, fungal or protozoal infection, caused by breaks (...) Folliculitis [7] Describe treatment of poison ivy “Allergic contact dermatitis is a form of delayed hypersensitivity mediated by lymphocytes sensitized by the contact of the allergen to the skin.The common Toxicodendron species, including poison ivy, oak, and sumac can produce a severe reaction. Toxicodendron species often result in vesicular or bullous eruptions. Oozing, crusting, scaling, and fissuring may be found along with lichenification in chronic lesions. The distribution of the eruption depends

2017 CandiEM

120. Moisturisers improve eczema symptoms and lessen the need for corticosteroids

the opportunity to choose between different moisturisers and use the ones that suit them best. Some may prefer using less oily creams during the day and thicker ointments at night. Share your views on the research. Why was this study needed? Eczema is a chronic skin disorder characterised by itchy dry skin. Scratching and cracking lead to further damage with redness, crusts, and oozing, and the itching can result in sleep deprivation and have a considerable impact on quality of life. Eczema often develops (...) Task Force on Atopic Dermatitis. . Dermatology. 1993;186:23-31. NICE. . London: National Institute for Health and Clinical Excellence; 2007. SIGN. . Edinburgh: Scottish intercollegiate guidelines network; 2011. Why was this study needed? Eczema is a chronic skin disorder characterised by itchy dry skin. Scratching and cracking lead to further damage with redness, crusts, and oozing, and the itching can result in sleep deprivation and have a considerable impact on quality of life. Eczema often

2019 NIHR Dissemination Centre

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>