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2541. Psoriasis or crusted scabies. Full Text available with Trip Pro

Psoriasis or crusted scabies. We describe a case of a 67-year-old woman with a 1-year history of nail thickening and a non-itchy erythematous scaly eruption on the fingertips. She was diagnosed with psoriasis and started on methotrexate after having had no response to topical calcipotriol. The diagnosis was reviewed after it was revealed by another consultant that the patient's husband had been attending dermatology clinics for several years with chronic pruritus, which had been repeatedly (...) thought to be due to scabies. Our patient was found to have crusted scabies after a positive skin scraping showed numerous mites. She was treated with topical permethrin, keratolytics and oral ivermectin. We also review the literature on crusted scabies and its management, with recommendations.

2008 Clinical & Experimental Dermatology

2542. Total Knee Arthroplasty Using a Pie-crusting Technique for Valgus Deformity. (Abstract)

Total Knee Arthroplasty Using a Pie-crusting Technique for Valgus Deformity. Valgus deformity correction with total knee arthroplasty is challenging. We hypothesized selective release of the tight lateral structures (pie-crusting technique), and of the lateral retinaculum in case of patellar maltracking, would obtain and maintain correction of the frontal plane deformity, restore patellar tracking and function, and avoid the complications of the extensive releases, including lateral condyle (...) avascularity and residual lateral instability. We followed 48 patients with 53 valgus knees who underwent TKA and were followed a minimum of 5 years (mean, 8 years; range, 5-12 years). Soft tissue balancing of the lateral structures was performed with the pie-crusting technique. We employed either a fixed posterior stabilized or a mobile implant. A lateral release was performed in 67% of the cases. We observed one postoperative complication, a transient postoperative peroneal nerve palsy that spontaneously

2007 Clinical Orthopaedics and Related Research

2543. Identification and characterization of Sarcoptes scabiei and Dermatophagoides pteronyssinus glutathione S-transferases: implication as a potential major allergen in crusted scabies. (Abstract)

Identification and characterization of Sarcoptes scabiei and Dermatophagoides pteronyssinus glutathione S-transferases: implication as a potential major allergen in crusted scabies. The astigmatid mite Sarcoptes scabiei is the causative agent of scabies, a highly infectious parasitic disease of the skin. Although the mite causes marked hypersensitivity reactions, particularly in crusted (severe) scabies, little is known about the specific scabies mite molecules involved in such immunologic (...) responses. We have identified six genes encoding scabies mite homologues of mu and delta-like glutathione S-transferases (GSTs) as well as novel house dust mite GSTs. A mu class S. scabiei GST was subcloned into a prokaryotic expression system. The purified recombinant protein rSsGST01 reacted strongly with IgE and IgG4 in sera from crusted scabies patients. This response was not observed with control antigens or with ordinary scabies and uninfested patient sera. In addition, the specific IgE response

2005 American Journal of Tropical Medicine & Hygiene

2544. Crusted scabies: clinical and immunological findings in seventy-eight patients and a review of the literature. (Abstract)

Crusted scabies: clinical and immunological findings in seventy-eight patients and a review of the literature. To describe the clinical and immunological features of crusted scabies in a prospectively ascertained cohort of 78 patients.All patients requiring inpatient treatment for crusted scabies in the 'top end' of the northern territory of Australia over a 10 year period were prospectively identified. Demographics, risk factors, and immunological parameters were retrospectively compiled from (...) their medical records and pathology databases.More than half the patients with crusted scabies had identifiable immunosuppressive risk factors. Eosinophilia and elevated IgE levels occurred in 58% and 96% of patients, respectively, with median IgE levels 17 times the upper limit of normal. Seventeen percent had a history of leprosy but 42% had no identifiable risk factors. There was a decrease in mortality after the introduction of a treatment protocol consisting of multiple doses of ivermectin combined

2005 Journal of Infection

2545. Crusted Norwegian scabies in an adult with Langerhans cell histiocytosis: mishaps leading to systemic chemotherapy. Full Text available with Trip Pro

Crusted Norwegian scabies in an adult with Langerhans cell histiocytosis: mishaps leading to systemic chemotherapy. Crusted Norwegian scabies is a rare hyperkeratotic variant of scabies infestation. We report herein a case of crusted scabies in a woman with underlying Langerhans cell histiocytosis (LCH).A 49-year-old woman with LCH was hospitalized owing to marked thrombocytopenia. Her hyperkeratotic skin eruption was thought to be secondary to LCH because several years earlier, she had

2007 Archives of Dermatology

2546. A two-reservoir recycling model for mantle-crust evolution Full Text available with Trip Pro

A two-reservoir recycling model for mantle-crust evolution The exact solutions for the isotopic compositions and the concentrations of the two-reservoir model for mantle-crust evolution are given for arbitrary rates of crustal growth and of back flow to the mantle. The critical parameters are the chemical fractionation factors for crustal growth and refluxing and the integrated fractional mass-removal rates from the crust and the mantle. For the case where refluxing is proportional to crustal (...) growth, all the solutions reduce to simple analytic expressions. The expression for the mean age of the mass of the crust with refluxing is given. If refluxing is significant, the model shows that highly incompatible elements have short residence times in the mantle. With plausible concentration values, material balance implies that the continents were derived from only a small fraction of the mantle.

1980 Proceedings of the National Academy of Sciences of the United States of America

2547. Management of post-ethmoidectomy crust formation: randomized single-blind clinical trial comparing pressurized seawater versus antiseptic/mucolytic saline. (Abstract)

Management of post-ethmoidectomy crust formation: randomized single-blind clinical trial comparing pressurized seawater versus antiseptic/mucolytic saline. This study compared the efficacy of mechanical nasal lavages with pressurized seawater versus nasal irrigations with saline plus benzododecinium (antiseptic) plus oleosorbate (mucolytic). Twenty patients agreed to participate in a randomized, single-blind clinical trial. All patients underwent endoscopic endonasal ethmoidectomy for nasal (...) polyps. The packing was removed after 48 h and patients were asked to start the same day nasal lavages three times a day. Clinical evaluations were performed: (1) by weighing residual nasal crusts and secretions after 21 +/- 2 days; and (2) by using visual analogue scales to daily record symptom scores. Data are presented as mean +/- SEM. T-test statistics for two independent groups were applied. The mean residual crust and secretion weights were 1,756 +/- 688 mg and 1,033 +/- 422 mg

1996 Rhinology Controlled trial quality: uncertain

2548. Crusted ("Norwegian") scabies in a specialist HIV unit. Full Text available with Trip Pro

Crusted ("Norwegian") scabies in a specialist HIV unit. 9038654 1997 03 11 2018 11 13 0266-4348 72 6 1996 Dec Genitourinary medicine Genitourin Med Crusted ("Norwegian") scabies in a specialist HIV unit. 453 Nandwani R R Pozniak A L AL Fuller L C LC Wade J J eng Comment Letter England Genitourin Med 8503853 0266-4348 IM X Genitourin Med. 1996 Apr;72(2):115-7 8698358 AIDS-Related Opportunistic Infections Cross Infection Humans Infection Control Scabies therapy 1996 12 1 1996 12 1 0 1 1996 12 1 0

1996 Genitourinary Medicine

2549. Crusted ("Norwegian") scabies in a specialist HIV unit: successful use of ivermectin and failure to prevent nosocomial transmission. Full Text available with Trip Pro

Crusted ("Norwegian") scabies in a specialist HIV unit: successful use of ivermectin and failure to prevent nosocomial transmission. A nosocomial outbreak of scabies in a specialist inpatient HIV unit resulted from a patient admitted with crusted scabies. Treatment of his infestation with topical scabicides alone failed and he remained infectious for several weeks. His infestation was then eradicated with combined topical treatment and oral ivermectin. In total, 14 (88%) out of 19 ward staff (...) became symptomatic, and 4 (21%) had evidence of scabies on potassium hydroxide examination of skin scrapings. The ward infection control policy was changed to distinguish patients with crusted scabies from those with ordinary scabies. A second patient with crusted scabies was treated with combined oral and topical therapy early in his admission and nursed with more stringent isolation procedures. No nosocomial transmission occurred and his infestation responded rapidly to treatment. Patients

1996 Genitourinary Medicine

2550. Dermacase. Crusted Norwegian scabies. Full Text available with Trip Pro

Dermacase. Crusted Norwegian scabies. 10386207 1999 08 31 2018 11 13 0008-350X 45 1999 Jun Canadian family physician Medecin de famille canadien Can Fam Physician Dermacase. Crusted Norwegian scabies. 1455, 1462 Adams S P SP University of Calgary. eng Case Reports Journal Article Canada Can Fam Physician 0120300 0008-350X 0 Insecticides 0 Pyrethrins 509F88P9SZ Permethrin IM Aged Animals Diagnosis, Differential Humans Insecticides therapeutic use Keratoderma, Palmoplantar etiology Male Nursing

1999 Canadian Family Physician

2551. New insights into disease pathogenesis in crusted (Norwegian) scabies: the skin immune response in crusted scabies. (Abstract)

New insights into disease pathogenesis in crusted (Norwegian) scabies: the skin immune response in crusted scabies. Crusted scabies is a rare and severely debilitating disease characterized by infestation of the skin with up to millions of Sarcoptes scabiei mites, high total IgG levels, extremely high total IgE levels, and the development of hyperkeratotic skin crusts that may be loose, scaly and flaky or thick and adherent.To describe crusted scabies skin pathogenesis and identify markers (...) associated with an inappropriate immune response leading to disease progression.Serial sections from skin biopsies obtained from two patients with severe crusted scabies were examined by immunohistochemistry for cell surface markers and inflammatory and regulatory cytokines. Concurrent levels of total B- and T-cell subsets and IgE, IgA, IgM, IgG and IgG subclasses were analysed in the blood. In addition antibody levels were recorded in a further 33 patients with crusted scabies and 14 patients

2008 British Journal of Dermatology

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