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Cranial Nerve 10

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61. Clinical correlation of imaging findings in congenital cranial dysinnervation disorders involving abducens nerve (Full text)

Clinical correlation of imaging findings in congenital cranial dysinnervation disorders involving abducens nerve High-resolution magnetic resonance imaging (MRI) of intracranial parts of sixth nerve and seventh nerve and the extraocular muscles (EOMs) in orbit to correlate the clinical characteristics in patients with two special forms of strabismus in congenital cranial dysinnervation disorders which are Duane's retraction syndrome (DRS) and Mobius syndrome.Morphological analysis by 3T MRI (...) of orbit (using surface coils) and brain (using 32 channel head coil) was performed on 6 patients with clinical DRS (1 bilateral), 2 cases with Mobius syndrome, and 1 case with congenital sixth nerve palsy. These were compared with findings in five controls.We observed absence/hypoplasia of sixth nerve in five out of seven eyes with DRS (71.42%), anomalous course in one eye, sixth and seventh nerve absence/hypoplasia in affected eyes with Mobius syndrome and bilateral absence/hypoplasia of the sixth

2017 Indian journal of ophthalmology PubMed

62. Vestigial-like 3 is a novel Ets1 interacting partner and regulates trigeminal nerve formation and cranial neural crest migration (Full text)

Vestigial-like 3 is a novel Ets1 interacting partner and regulates trigeminal nerve formation and cranial neural crest migration Drosophila Vestigial is the founding member of a protein family containing a highly conserved domain, called Tondu, which mediates their interaction with members of the TEAD family of transcription factors (Scalloped in Drosophila). In Drosophila, the Vestigial/Scalloped complex controls wing development by regulating the expression of target genes through binding (...) to MCAT sequences. In vertebrates, there are four Vestigial-like genes, the functions of which are still not well understood. Here, we describe the regulation and function of vestigial-like 3 (vgll3) during Xenopus early development. A combination of signals, including FGF8, Wnt8a, Hoxa2, Hoxb2 and retinoic acid, limits vgll3 expression to hindbrain rhombomere 2. We show that vgll3 regulates trigeminal placode and nerve formation and is required for normal neural crest development by affecting

2017 Biology open PubMed

63. Cranial Nerve Palsy after Onyx Embolization as a Treatment for Cerebral Vascular Malformation (Full text)

Cranial Nerve Palsy after Onyx Embolization as a Treatment for Cerebral Vascular Malformation The Onyx liquid embolic system is a relatively safe and commonly used treatment for vascular malformations, such as arteriovenous fistulas and arteriovenous malformations. However, studies on possible complications after Onyx embolization in patients with vascular malformations are limited, and the occurrence of cranial nerve palsy is occasionally reported. Here we report the progress of two different (...) types of cranial nerve palsy that can occur after embolization. In both cases, Onyx embolization was performed to treat vascular malformations and ipsilateral oculomotor and facial nerve palsies were observed. Both patients were treated with steroids and exhibited symptom improvement after several months. The most common types of neuropathy that can occur after Onyx embolization are facial nerve palsy and trigeminal neuralgia. Although the mechanisms underlying these neuropathies are not clear

2017 Journal of cerebrovascular and endovascular neurosurgery PubMed

64. Comparison of Diffusion-Weighted MRI Reconstruction Methods for Visualization of Cranial Nerves in Posterior Fossa Surgery (Full text)

of each method for cranial nerve reconstruction and how this methodology can assist surgical decision-making is still understudied. Images from 10 patients with posterior fossa tumors (4 male, mean age: 63.5), affecting either the trigeminal nerve (CN V) or the facial/vestibular complex (CN VII/VIII), were employed. Three distinct reconstruction methods [two tensor-based methods: single diffusion tensor tractography (SDT) (3D Slicer), eXtended streamline tractography (XST), and one fiber orientation (...) Comparison of Diffusion-Weighted MRI Reconstruction Methods for Visualization of Cranial Nerves in Posterior Fossa Surgery Diffusion-weighted imaging (DWI)-based tractography has gained increasing popularity as a method for detailed visualization of white matter (WM) tracts. Different imaging techniques, and more novel, advanced imaging methods provide significant WM structural detail. While there has been greater focus on improving tract visualization for larger WM pathways, the relative value

2017 Frontiers in neuroscience PubMed

65. Cranial Nerve Lymphomatosis Magnetic Resonance Imaging Findings in a Case of Mantle Cell Lymphoma (Full text)

Cranial Nerve Lymphomatosis Magnetic Resonance Imaging Findings in a Case of Mantle Cell Lymphoma 29234188 2018 11 13 0253-0716 42 5 2017 Sep Iranian journal of medical sciences Iran J Med Sci Cranial Nerve Lymphomatosis Magnetic Resonance Imaging Findings in a Case of Mantle Cell Lymphoma. 512-513 Yılmaz Güliz G Department of Radiology, Gaziosmanpaşa Hospital, Istanbul Yeni Yüzyıl University, Istanbul, Turkey. Akpınar Süha S Department of Radiology, Near East University Hospital, Nicosia

2017 Iranian journal of medical sciences PubMed

66. CD56-Negative Aggressive NK Cell Leukemia Relapsing as Multiple Cranial Nerve Palsies: Case Report and Literature Review (Full text)

CD56-Negative Aggressive NK Cell Leukemia Relapsing as Multiple Cranial Nerve Palsies: Case Report and Literature Review Aggressive natural killer cell leukemia (ANKL) is extremely rare and habitually manifests as a systemic disease with multiorgan failure that rapidly evolves to death. The neoplastic natural killer (NK) cells usually harbor the Epstein-Barr virus (EBV) with a latent viral infection pattern type II; they often have a cytoplasmic CD3ε+ and surface CD3-, CD2+, and CD56 (...) in the diagnosis of an EBV-positive, CD56-negative ANKL. The patient failed to respond to gemcitabine and cisplatin-based polychemotherapy, dying three months later with leukemic meningitis and multiple cranial nerves palsies.The diagnosis of ANKL is difficult and requires both clinical suspicion and an extensive laboratorial approach. Absence of CD56 expression on the neoplastic NK cells may impose difficulties in the diagnosis, which requires morphological, immunophenotypic, histopathological

2017 Case reports in hematology PubMed

67. Functional Recovery of Cranial Nerves in Patients with Traumatic Orbital Apex Syndrome (Full text)

Functional Recovery of Cranial Nerves in Patients with Traumatic Orbital Apex Syndrome Traumatic orbital apex syndrome (TOAS) is a rare disease characterized by the damage of cranial nerves (CNs) II, III, IV, and VI. The aim of our study was to analyze the functional recovery of CNs in TOAS and discuss the management of these patients.We retrospectively reviewed 28 patients with TOAS treated in the Department of Neurosurgery, Shanghai Changzheng Hospital from February 2006 to February 2016

2017 BioMed research international PubMed

68. Isolated cranial nerve III palsy as the presenting manifestation of HIV-related large B-cell lymphoma: clinical, radiological and postmortem observations: report of a case and review of the literature. (PubMed)

were positive. Postmortem examination of the brain revealed malignant lymphomatous cell infiltration of both cranial nerve III, diffuse leptomeningeal disease and focal superficial subependymal and subpial invasion. Based on our review of the literature, we were able to find only 10 detailed cases of cranial nerve III palsy as the presenting manifestation of central nervous system lymphoma. Furthermore, none of the previously reported cases correlated the magnetic resonance imaging findings (...) Isolated cranial nerve III palsy as the presenting manifestation of HIV-related large B-cell lymphoma: clinical, radiological and postmortem observations: report of a case and review of the literature. Rarely can a neurologically isolated cranial nerve III palsy be the presenting manifestation of central nervous system lymphoma. We detail the clinical, radiological, and pathological features of a previously healthy 45-year-old man presenting with an isolated, pupil-involving, right cranial

2017 Survey of Ophthalmology

69. Cranial orthotic devices for the treatment of positional cranial deformity

Cranial orthotic devices for the treatment of positional cranial deformity Cranial orthotic devices for the treatment of positional cranial deformity Cranial orthotic devices for the treatment of positional cranial deformity Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Cranial orthotic devices for the treatment of positional cranial deformity. Lansdale: HAYES (...) , Inc.. Directory Publication. 2014 Authors' objectives Cranial orthotic devices are used to redirect growth of the skull bones and reduce cranial asymmetry in infants who have positional cranial deformity. Final publication URL The report may be purchased from: Indexing Status Subject indexing assigned by CRD MeSH Craniofacial Abnormalities; Humans; Orthotic Devices Language Published English Country of organisation United States English summary An English language summary is available. Address

2014 Health Technology Assessment (HTA) Database.

70. Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone To Prophylactic Cranial Irradiation And Consolidative Extra-Cranial Irradiation For Extensive Disease Small Cell Lung Cancer (ED-SCLC): NRG Oncology RTOG 0937. (Full text)

Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone To Prophylactic Cranial Irradiation And Consolidative Extra-Cranial Irradiation For Extensive Disease Small Cell Lung Cancer (ED-SCLC): NRG Oncology RTOG 0937. NRG Oncology RTOG 0937 is a randomized phase II trial evaluating 1-year overall survival (OS) with prophylactic cranial irradiation (PCI) or PCI plus consolidative radiation therapy (PCI+cRT) to intrathoracic disease and extracranial metastases for extensive (...) -disease SCLC.Patients with one to four extracranial metastases were eligible after a complete response or partial response to chemotherapy. Randomization was to PCI or PCI+cRT to the thorax and metastases. Original stratification included partial response versus complete response after chemotherapy and one versus two to four metastases; age younger than 65 years versus 65 years or older was added after an observed imbalance. PCI consisted of 25 Gy in 10 fractions. cRT consisted of 45 Gy in 15

2017 Journal of Thoracic Oncology PubMed

71. The Effectiveness and Risks of Cranial Electrical Stimulation

The Effectiveness and Risks of Cranial Electrical Stimulation Management Briefs eBrief-no120 -- Enter search terms Button to search HSRD ® Inside VA Budget and Performance Inside the News Room National Observances Special Events » » » » » Management Briefs eBrief-no120 -- Health Services Research & Development Management eBrief no. 120 » Issue 120 December 2016 The report is a product of the VA/HSR&D Evidence Synthesis Program. The Effectiveness and Risks of Cranial Electrical Stimulation (...) : A Systematic Review Cranial electrical stimulation (CES) is a non-invasive method of applying low-intensity electrical current to the head. It is related to but distinct from other forms of transcranial electrical stimulation (i.e., electroconvulsive therapy and transcranial direct current stimulation), with different versions of stimulation varying in the placement of electrodes, intensity of the current, and waveform of the current. After an initial burst of research activity in the 1970s and early 1980s

2017 Veterans Affairs - R&D

72. Cranial Neuropathy

of the Department of Army/Navy/Air Force, Department of Defense, or United States Government. Reprint requests to: publications@acr.org ACR Appropriateness Criteria ® 10 Cranial Neuropathy 3. Because of the close proximity of many cranial nerve nuclei and of many exiting sites of the nerves themselves, some mass lesions may involve multiple cranial nerves. Special Imaging Considerations In the evaluation of cranial neuropathy complete evaluation of the nerves from their brain stem nuclei to their “end organs (...) College of Radiology. ACR Appropriateness Criteria®: Hearing Loss and/or Vertigo. Available at: https://acsearch.acr.org/docs/69488/Narrative/. Accessed March 1, 2017. 6. Chen RC, Khorsandi AS, Shatzkes DR, Holliday RA. The radiology of referred otalgia. AJNR Am J Neuroradiol. 2009;30(10):1817-1823. 7. Casselman J, Mermuys K, Delanote J, Ghekiere J, Coenegrachts K. MRI of the cranial nerves--more than meets the eye: technical considerations and advanced anatomy. Neuroimaging Clin N Am. 2008;18(2):197

2017 American College of Radiology

73. Third, Fourth, and Sixth Cranial Nerve Palsies in Pituitary Apoplexy (Full text)

Third, Fourth, and Sixth Cranial Nerve Palsies in Pituitary Apoplexy Pituitary apoplexy (PA) often presents with acute headache and neuro-ophthalmic manifestations, including ocular motility dysfunction (OMD) from cranial nerve palsies (CNPs). Our goal was to describe the epidemiology and outcomes of OMD in a large, single-center series of patients with PA.We conducted a retrospective chart review of all patients with PA seen in our pituitary center between January 1995 and December 2012

2016 World neurosurgery PubMed

74. A pediatric case of pituitary macroadenoma presenting with pituitary apoplexy and cranial nerve involvement: case report (Full text)

A pediatric case of pituitary macroadenoma presenting with pituitary apoplexy and cranial nerve involvement: case report Pituitary adenomas usually arise from the anterior lobe of the pituitary gland and are manifested with hormonal disorders or mass effect. Mass effect usually occurs in nonfunctional tumors. Pituitary adenomas may be manifested with visual field defects or rarely in the form of total oculomotor palsy. Visual field defect is most frequently in the form of bitemporal hemianopsia (...) and limited outward gaze in the left eye following trauma and who was found to have pituitary macroadenoma causing compression of the optic chiasma and optic nerve on the left side on cranial and pituitary magnetic resonance imaging.

2016 Turkish Archives of Pediatrics/Türk Pediatri Arşivi PubMed

75. Lyme Disease Presenting with Multiple Cranial Nerve Deficits: Report of a Case (Full text)

Lyme Disease Presenting with Multiple Cranial Nerve Deficits: Report of a Case Lyme disease is a tick-transmitted multisystem inflammatory disease caused by the spirochete Borrelia burgdorferi. With more than 25,000 CDC reported cases annually, it has become the most common vector-borne disease in the United States. We report a case of 38-year-old man with Lyme disease presenting with simultaneous palsy of 3rd, 5th, 7th, 9th, and 10th cranial nerves.

2016 Case Reports in Emergency Medicine PubMed

76. Isolated neurosarcoidosis presenting with multiple cranial nerve palsies (Full text)

Isolated neurosarcoidosis presenting with multiple cranial nerve palsies As an extremely rare subtype of sarcoidosis that develops exclusively in the nervous system, isolated neurosarcoidosis is difficult to diagnose. In addition, its exact clinical features are not known.A 61-year-old man presented with right ear hearing loss, diplopia, and fever. Computed tomography (CT) and magnetic resonance imaging revealed mass lesions in the right cerebellum and left side body of the lateral ventricle

2016 Surgical neurology international PubMed

77. Fast imaging employing steady-state acquisition (FIESTA) MRI to investigate cerebrospinal fluid (CSF) within dural reflections of posterior fossa cranial nerves (Full text)

Fast imaging employing steady-state acquisition (FIESTA) MRI to investigate cerebrospinal fluid (CSF) within dural reflections of posterior fossa cranial nerves There is no consensus approach to covering skull base meningeal reflections-and cerebrospinal fluid (CSF) therein-of the posterior fossa cranial nerves (CNs VII-XII) when planning radiotherapy (RT) for medulloblastoma and ependymoma. We sought to determine whether MRI and specifically fast imaging employing steady-state acquisition

2016 The British journal of radiology PubMed

78. Cranial Nerves Tractography

Cranial Nerves Tractography Cranial Nerves Tractography - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Cranial Nerves Tractography (CN Tracto) The safety and scientific validity of this study (...) Description Go to Brief Summary: Introduction: The skull base tumors surgery remains a challenge since numerous cranial nerves or vessels closely surround them. Recently, diffusion tensor imaging has developed with the tractography following white fibers and visualizing functional tracts. Cranial nerves tractography could allow predicting their displacement by skull base tumors that may help the surgeon to spare them along the surgery. Methods: Preoperative cerebral MRI was performed on patients who

2016 Clinical Trials

79. Comparison of probabilistic and deterministic fiber tracking of cranial nerves. (Full text)

toward significance in probabilistic tracking (p = 0.06). In the clinical cases, the probabilistic method visualized 7 of 10 attempted CNs accurately, compared with 3 correct depictions with deterministic tracking. CONCLUSIONS High angular resolution DTI scans are preferable for the DTI-based depiction of the cranial nerves. Probabilistic tracking with a gradual PICo threshold increase is more effective for this task than the previously described deterministic tracking with a gradual FA threshold (...) Comparison of probabilistic and deterministic fiber tracking of cranial nerves. OBJECTIVE The depiction of cranial nerves (CNs) using diffusion tensor imaging (DTI) is of great interest in skull base tumor surgery and DTI used with deterministic tracking methods has been reported previously. However, there are still no good methods usable for the elimination of noise from the resulting depictions. The authors have hypothesized that probabilistic tracking could lead to more accurate results

2016 Journal of Neurosurgery PubMed

80. Carotid artery and lower cranial nerve exposure with increasing surgical complexity to the parapharyngeal space. (PubMed)

Carotid artery and lower cranial nerve exposure with increasing surgical complexity to the parapharyngeal space. To investigate the extent of carotid artery exposure attained, including the identification of the external carotid branches and lower cranial nerves in five sequential external approaches to the parapharyngeal space, and to provide an anatomical algorithm.Anatomical study.Six latex-injected adult cadaver heads were dissected in five consecutive approaches: transcervical approach (...) with submandibular gland removal, posterior extension of the transcervical approach, transcervical approach with parotidectomy, parotidectomy with lateral mandibulotomy, and parotidectomy with mandibulectomy. The degree of carotid artery exposure attained, external carotid branches, and lower cranial nerves visualized was documented.The transcervical approach exposed 1.5 cm (Standard Deviation (SD) 0.5) of internal carotid artery (ICA) and 1.25 cm (SD 0.25) of external carotid artery (ECA). The superior thyroid

2016 Laryngoscope

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