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Cranial Nerve 10

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221. Re: Comments on “Neuromuscular Ultrasonography of Cranial Nerves”: The Authors Respond Full Text available with Trip Pro

Re: Comments on “Neuromuscular Ultrasonography of Cranial Nerves”: The Authors Respond 28406589 2018 11 13 1738-6586 13 2 2017 04 Journal of clinical neurology (Seoul, Korea) J Clin Neurol Re: Comments on "Neuromuscular Ultrasonography of Cranial Nerves": The Authors Respond. 214 10.3988/jcn.2017.13.2.214 Tawfik Eman A EA Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Ain Shams University, Cairo, Egypt. Walker Francis O FO Department of Neurology, Medical Center

2017 Journal of clinical neurology (Seoul, Korea)

222. Scalloping Characteristics in a Patient with Extra-Cranial Hemangioma Full Text available with Trip Pro

Scalloping Characteristics in a Patient with Extra-Cranial Hemangioma Infantile hemangiomas are the most common benign tumors of infancy and childhood with a reported incidence of 4% to 10% in infants. We report of a 9 year-old male child with a history of progressively increasing swelling over the right eyebrow region. The lesion was present since childhood; however, it increased in in size over the previous 3-4 months. The CT scan showed scalloping over the right supra-orbital ridge

2017 Polish Journal of Radiology

223. Diagnostic Challenge: Sequential Unilateral Cranial Neuropathies Due to Perineural Spread of Carcinoma Full Text available with Trip Pro

Diagnostic Challenge: Sequential Unilateral Cranial Neuropathies Due to Perineural Spread of Carcinoma An 86-year old man developed sequential dysfunction of trigeminal (V1), facial, abducens, trigeminal (v2), oculomotor, and hypoglossal cranial nerves on the right over 20 months. Magnetic resonance imaging (MRI) showed a lesion in the right cavernous sinus. Although there was clinical suspicion that this was related to perineural spread of an extracranial tumour, a primary lesion

2017 Neuro-Ophthalmology

224. Ocular congenital cranial dysinnervation disorders (CCDDs): insights into axon growth and guidance Full Text available with Trip Pro

Ocular congenital cranial dysinnervation disorders (CCDDs): insights into axon growth and guidance Unraveling the genetics of the paralytic strabismus syndromes known as congenital cranial dysinnervation disorders (CCDDs) is both informing physicians and their patients and broadening our understanding of development of the ocular motor system. Genetic mutations underlying ocular CCDDs alter either motor neuron specification or motor nerve development, and highlight the importance of modulations (...) of the orbital innervation in mice lacking Mafb has established that the stereotypical misinnervation of the lateral rectus by fibers of the oculomotor nerve in DRS is secondary to absence of the abducens nerve. Studies of a CHN1 mouse model have begun to elucidate mechanisms of selective vulnerability in the nervous system.© The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

2017 Human molecular genetics

225. Delayed Lower Cranial Neuropathy after Oropharyngeal IMRT: A Cohort Analysis and Literature Review Full Text available with Trip Pro

Delayed Lower Cranial Neuropathy after Oropharyngeal IMRT: A Cohort Analysis and Literature Review The purpose of this study was to examine swallowing-related lower cranial nerve palsy (LCNP) in oropharyngeal cancer (OPC) survivors after intensity-modulated radiotherapy (IMRT).Patients treated with definitive IMRT (66-72 Gy) were pooled from institutional trial databases. Prospective analyses on parent trials included videofluoroscopy, clinical LCNP examination, and questionnaires pre-IMRT, 6

2017 Head & neck

226. Complete Cranial Iliac Osteotomy to Approach the Lumbosacral Foramen Full Text available with Trip Pro

Complete Cranial Iliac Osteotomy to Approach the Lumbosacral Foramen An approach using a complete cranial iliac osteotomy (CCIO) to access the lumbosacral (LS) foramen in dogs from lateral was developed using cadavers and applied in a clinical patient with degenerative lumbosacral stenosis (DLSS). The foraminal enlargement in the cadavers and the patient was documented on postoperative CT scans. The preoperative CT scan of the patient showed moderate cranial telescoping of the sacral roof (...) and a moderate central disk protrusion, leading to moderate to severe compression of the cauda equina. In addition, there was lateral spondylosis with consequential stenosis of the right LS foramen. The right L7 nerve had lost its fat attenuation and appeared thickened. After a routine L7S1 dorsal laminectomy with a partial discectomy, a CCIO was performed, providing good access to the LS foramen and the adhesions around the proximal L7 nerve caudoventral to the foramen. The osteotomy was stabilized

2017 Frontiers in veterinary science

227. The p75 neurotrophin receptor regulates cranial irradiation-induced hippocampus-dependent cognitive dysfunction Full Text available with Trip Pro

regulation of spine density, which are associated with various neurological disorders. In this study, male Sprague-Dawley (SD) rats received 10 Gy cranial irradiation. Then, we evaluated the expression of p75NTR in the hippocampus after cranial irradiation and explored its potential role in radiation-induced synaptic dysfunction and memory deficits. We found that the expression of p75NTR was significantly increased in the irradiated rat hippocampus. Knockdown of p75NTR by intrahippocampal infusion (...) The p75 neurotrophin receptor regulates cranial irradiation-induced hippocampus-dependent cognitive dysfunction Cognitive deficits, characterized by progressive problems with hippocampus-dependent learning, memory and spatial processing, are the most serious complication of cranial irradiation. However, the underlying mechanisms remain obscure. The p75 neurotrophin receptor (p75NTR) is involved in a diverse arrays of cellular responses, including neurite outgrowth, neurogenesis, and negative

2017 Oncotarget

228. Macroscopic Innervation of the Dura Mater Covering the Middle Cranial Fossa in Humans Correlated to Neurovascular Headache Full Text available with Trip Pro

Macroscopic Innervation of the Dura Mater Covering the Middle Cranial Fossa in Humans Correlated to Neurovascular Headache The trigeminovascular system within the cranial dura mater is a possible cause of headaches. The aim of this study is to investigate macroscopically dural innervation around the middle meningeal artery (MMA) in the middle cranial fossa. Forty-four sides of the cranial dura overlying the skull base obtained from 24 human cadavers were stained using Sihler's method. Overall (...) , the nervus spinosus (NS) from either the maxillary or mandibular trigeminal divisions ran along the lateral wall of the middle meningeal vein rather than that of the MMA. Distinct bundles of the NS running along the course of the frontal branches of the MMA were present in 81.8% of cases (N = 36). Others did not form dominant nerve bundles, instead giving off free nerve endings along the course of the MMA or dural connective tissue. The distribution of these nerve endings was similar

2017 Frontiers in neuroanatomy

229. Obsessive-Compulsive Disorder Associated with Posterior Cranial Fossa Meningioma Full Text available with Trip Pro

criteria such as depression. One month after giving childbirth, the symptoms worsened, while headache and dizziness also developed. The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) score was 34. The patient was examined for a headache and a posterior cranial fossa meningioma was found. Following resection of the meningioma, the OCD symptoms were remarkably reduced (Y-BOCS score 10). There is only one previous report of pure OCD associated with a cerebellar mass and the present findings should help (...) Obsessive-Compulsive Disorder Associated with Posterior Cranial Fossa Meningioma We report here a patient in whom the effects of a cerebellum mass may have led to development of obsessive-compulsive disorder (OCD). A 33-year-old woman showed symptoms of OCD, including obsessive worry about infection from tainted blood and repetitive confirmation, which worsened during pregnancy. She had comprehension in regard to her illness and no evidence of cognitive dysfunction and did not meet other DSM-5

2017 Case reports in psychiatry

230. Low‐level laser therapy (780 nm) combined with collagen sponge scaffold promotes repair of rat cranial critical‐size defects and increases TGF‐β, FGF‐2, OPG/RANK and osteocalcin expression Full Text available with Trip Pro

Low‐level laser therapy (780 nm) combined with collagen sponge scaffold promotes repair of rat cranial critical‐size defects and increases TGF‐β, FGF‐2, OPG/RANK and osteocalcin expression The aim of this study was to evaluate the effect of collagen sponge scaffold (CSS) implantation associated with low-level laser therapy (LLLT) on repairing bone defects. A single 5-mm cranial defect was surgically created in forty Wistar rats, which then received one of the following four (...) interventions (n = 10 per group): no treatment (G0); bone defect implanted with collagen sponge scaffold (CSS) alone (G1); defect treated with low-level laser therapy (LLLT) (wavelength 780 nm; total energy density 120 J/cm2 ; power 50 mW) alone (G2); and CSS associated with LLLT treatment (G3). After surgery, animals in each group were euthanized at 21 days and 30 days (n = 5 per euthanasia time group). Bone formation was monitored by X-ray imaging analysis. Biopsies were collected and processed

2017 International journal of experimental pathology

231. Highly Conformal Craniospinal Radiotherapy Techniques Can Underdose the Cranial Clinical Target Volume if Leptomeningeal Extension through Skull Base Exit Foramina is not Contoured Full Text available with Trip Pro

Highly Conformal Craniospinal Radiotherapy Techniques Can Underdose the Cranial Clinical Target Volume if Leptomeningeal Extension through Skull Base Exit Foramina is not Contoured Craniospinal irradiation (CSI) remains a crucial treatment for patients with medulloblastoma. There is uncertainty about how to manage meningeal surfaces and cerebrospinal fluid (CSF) that follows cranial nerves exiting skull base foramina. The purpose of this study was to assess plan quality and dose coverage (...) of posterior cranial fossa foramina with both photon and proton therapy.We analysed the radiotherapy plans of seven patients treated with CSI for medulloblastoma and primitive neuro-ectodermal tumours and three with ependymoma (total n = 10). Four had been treated with a field-based technique and six with TomoTherapy™. The internal acoustic meatus (IAM), jugular foramen (JF) and hypoglossal canal (HC) were contoured and added to the original treatment clinical target volume (Plan_CTV) to create a Test_CTV

2017 Clinical Oncology (Royal College of Radiologists (Great Britain)

232. Commentary: Complete Cranial Iliac Osteotomy to Approach the Lumbosacral Foramen Full Text available with Trip Pro

Commentary: Complete Cranial Iliac Osteotomy to Approach the Lumbosacral Foramen 28717639 2018 11 13 2297-1769 4 2017 Frontiers in veterinary science Front Vet Sci Commentary: Complete Cranial Iliac Osteotomy to Approach the Lumbosacral Foramen. 106 10.3389/fvets.2017.00106 Saulnier Troff Francois-Guillaume FG Soft Tissue/Orthopaedics/Neurosurgery Department, Veterinary Emergency and Specialty Hospital, Singapore. Motta Luca L Northwest Surgeons, Frodsham, United Kingdom. De Busscher Virginie V (...) Diagnostic Imaging Department, Veterinary Emergency and Specialty Hospital, Singapore. eng Journal Article Comment 2017 07 03 Switzerland Front Vet Sci 101666658 2297-1769 Front Vet Sci. 2017 May 19;4:75 28580360 dogs foraminotomy ilium lumbosacral region transiliac 2017 05 31 2017 06 20 2017 7 19 6 0 2017 7 19 6 0 2017 7 19 6 1 epublish 28717639 10.3389/fvets.2017.00106 PMC5494476 J Am Vet Med Assoc. 2002 Sep 15;221(6):807-10, 800 12322918 Vet Surg. 2007 Oct;36(7):705-13 17894598 Front Vet Sci. 2017 May

2017 Frontiers in veterinary science

233. Cranial Neuropathies and Neuromuscular Weakness: A Case of Mistaken Identity Full Text available with Trip Pro

Cranial Neuropathies and Neuromuscular Weakness: A Case of Mistaken Identity We describe a case of wound botulism initially thought to represent Miller-Fisher variant Guillain-Barré syndrome (MFS). Botulism classically presents with the so-called "four D's" (diplopia, dysarthria, dysphagia, dry mouth) with symmetric, descending weakness. MFS presents with a triad of limb-ataxia, areflexia, and ophthalmoplegia, with variable cranial nerve and extremity involvement. The distinction can

2017 Clinical Practice and Cases in Emergency Medicine

234. Analyses of distribution and dosimetry of brain metastases in small cell lung cancer with relation to the neural stem cell regions: feasibility of sparing the hippocampus in prophylactic cranial irradiation Full Text available with Trip Pro

Analyses of distribution and dosimetry of brain metastases in small cell lung cancer with relation to the neural stem cell regions: feasibility of sparing the hippocampus in prophylactic cranial irradiation This work aims to assess the feasibility of selectively sparing the hippocampus during prophylactic cranial irradiation (PCI) for small cell lung cancer (SCLC).SCLC patients with brain metastases (BMs) diagnosed with MRI were enrolled. Lesions localized to the neural stem cell (NSC (...) ) compartments [subventricular zone (SVZ) or hippocampus] were analyzed. Patients were categorized by the total number of intracranial metastases, the therapy processes and the symptoms. Hippocampi and enhanced lesions within 15 mm from the hippocampus were contoured. IMRT treatment plans were generated for hippocampal avoidance (HA)-PCI (25Gy in 10 fractions).From Jan 2011 to Oct 2014, 1511 metastases were identified in 238 patients. The overall ratio of metastatic lesions located in NSC regions was 2.0

2017 Radiation oncology (London, England)

235. A Rare Presentation of Cranial Polyneuropathy Without Rash Caused by Varicella Zoster Virus Full Text available with Trip Pro

A Rare Presentation of Cranial Polyneuropathy Without Rash Caused by Varicella Zoster Virus Varicella Zoster Virus (VZV) is associated with many disorders of the central and peripheral nervous systems including neuralgia, meningitis, meningoencephalitis, cerebellitis, vasculopathy, myelopathy, Ramsay-Hunt syndrome, and polyneuritis cranialis. Cranial nerves V, VI, VII, VIII, IX, X, XI, and/or XII may be affected. The neurological disorders caused by VZV usually present with rash, but may rarely (...) present without rash.We herein present a case of polyneuritis cranialis without rash caused by VZV affecting cranial nerves VII, VIII, IX, and X. After excluding other causes of the condition, we diagnosed VZV infection based on VZV DNA in the CSF and an elevated anti-VZV IgG level in serum. The patient responded well to antiviral therapy.VZV infection should be kept in mind during the differential diagnosis of polyneuritis cranialis; it is important to note that VZV re-activation may occur without

2017 Medical Archives

236. Multiple Primary Recurrent Basaliomas (mPR-BCCs) of the Scalp with Cranial Bone Invasion Full Text available with Trip Pro

surgery (MMS), with MMS being the gold standard for the definitive treatment of BCC. Improper removal or electrocautery (as in our case) of the several aggressive forms of BCC seems to be a particular problem, and not only for dermatologic surgeons. The risk of subsequent invasion and destruction of the cranium, underlying dura, and cranial nerves by basal cell carcinoma (BCC) is extremely low, with an estimated incidence of 0.03%, but is a potential complication over time. Computed tomography (...) Multiple Primary Recurrent Basaliomas (mPR-BCCs) of the Scalp with Cranial Bone Invasion We present a 68-year-old patient with multiple primary infiltrative BCCs in the scalp area, initially treated 14 years ago with superficial contact X-ray therapy, end dose 60 greys, followed by electrocautery (x2) several years later. He presented in the dermatologic policlinic for diagnosis and therapy of two additional, newly-formed pigmented lesions, and because of an uncomfortable, itchy, burning

2017 Open access Macedonian journal of medical sciences

237. Perihippocampal metastasis following hippocampus-avoiding prophylactic cranial irradiation for small cell lung cancer: a case report Full Text available with Trip Pro

Perihippocampal metastasis following hippocampus-avoiding prophylactic cranial irradiation for small cell lung cancer: a case report Prophylactic cranial irradiation (PCI) lowers the risk of brain metastasis (BM) and increases survival in small cell lung cancer (SCLC) patients, but it also entails a risk of neurocognitive dysfunction (NCD). One strategy to mitigate this neurotoxicity is hippocampus-avoiding (HA) whole-brain radiation therapy, as the hippocampus is mainly responsible (...) for radiation-related NCD and hippocampal or perihippocampal metastases are rare. A few prospective clinical trials have demonstrated a reduction in NCD following HA whole-brain radiation therapy. The 59-year-old male patient described in this report had limited-stage SCLC and a complete response to thoracic chemoradiotherapy. Seven months after receiving HA-PCI of 25 Gy in 10 fractions using intensity-modulated radiation therapy, a 36 mm solitary metastasis was detected in the right perihippocampal region

2017 OncoTargets and therapy

238. A congenital cranial dysinnervation disorder: Möbius’ syndrome Full Text available with Trip Pro

A congenital cranial dysinnervation disorder: Möbius’ syndrome Möbius' syndrome, also known as Möbius' sequence, is a nonprogressive cranial dysinnervation disorder characterized by congenital facial and abducens nerve paralysis. Here, we report a 5-day-old girl who was conceived after in vitro fertilization with poor suck and facial paralysis. She had bilaterally ptosis and lateral gaze limitation, left-sided deviation of the tongue, dysmorphic face, hypoplastic fingers and finger nails (...) on the left hand, and was diagnosed as having Möbius' syndrome. Involvement of other cranial nerves such as three, four, five, nine, 9 and 12, and limb malformations may accompany this syndrome. However, several factors have been proposed for the etiology, some rare cases have also been reported with artificial reproductive technologies. Feeding difficulties and aspiration are the main problems encountered in infancy. The other cranial nerves should be examined further in newborns who present

2017 Turkish Archives of Pediatrics/Türk Pediatri Arşivi

239. Effects of vacuum sealing drainage on the treatment of cranial bone-exposed wounds in rabbits Full Text available with Trip Pro

Effects of vacuum sealing drainage on the treatment of cranial bone-exposed wounds in rabbits This study was designed to assess the efficacy of vacuum sealing drainage (VSD) on skull exposure wounds in rabbits and to investigate the underlying mechanism of the process. Full-thickness excisional circular wounds 2×2 cm with or without periosteum involvement were created in 88 New Zealand white rabbits (mean body weight: 3.0±0.65 kg). Animals were randomly divided into 4 groups: periosteum-intact (...) the wound healing process significantly (P<0.05) compared to the corresponding control groups. VSD alleviated the inflammation reaction, accelerated re-epithelialization and facilitated the organization of collagen fibers into neat rows. During the wound healing process, the hydroxyproline content increased overtime [i.e., postoperative days (POD) 7, POD 10 and POD 15] in all four groups, and it peaked in the p+VSD group. VSD also promoted angiogenesis via increasing number and quality of collagen. We

2017 Brazilian Journal of Medical and Biological Research

240. Prophylactic cranial irradiation for stage IV small cell lung cancer, live longer or reduce morbidity of brain metastases? Full Text available with Trip Pro

Prophylactic cranial irradiation for stage IV small cell lung cancer, live longer or reduce morbidity of brain metastases? 29268344 2018 11 13 2072-1439 9 10 2017 Oct Journal of thoracic disease J Thorac Dis Prophylactic cranial irradiation for stage IV small cell lung cancer, live longer or reduce morbidity of brain metastases? 3572-3575 10.21037/jtd.2017.09.50 Postmus Pieter E PE Department of Medical Oncology, Clatterbridge Cancer Centre, Liverpool Heart & Chest Hospital, University (...) of Liverpool, Liverpool, UK. Smit Egbert F EF Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands. eng Editorial Comment China J Thorac Dis 101533916 2072-1439 Lancet Oncol. 2017 May;18(5):663-671 28343976 Conflicts of Interest: The authors have no conflicts of interest to declare. 2017 12 23 6 0 2017 12 23 6 0 2017 12 23 6 1 ppublish 29268344 10.21037/jtd.2017.09.50 jtd-09-10-3572 PMC5723843 Eur J Cancer. 1997 Oct;33(11):1752-8 9470828 Cancer. 2008 Apr 15;112(8):1827

2017 Journal of thoracic disease

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