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Cranial Nerve 10

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201. Does a "Fundal Fluid Cap" Predict Successful Hearing Preservation in Vestibular Schwannoma Resections Via the Middle Cranial Fossa Approach? (Abstract)

Does a "Fundal Fluid Cap" Predict Successful Hearing Preservation in Vestibular Schwannoma Resections Via the Middle Cranial Fossa Approach? To determine the association between radiographic cerebrospinal fluid (CSF) cap in the lateral internal auditory canal (IAC) and likelihood of successful hearing preservation in middle cranial fossa (MCF) vestibular schwannoma (VS) surgery.Retrospective chart review.Academic tertiary referral center.One hundred thirty-eight consecutive patients (mean age (...) fluid size was stratified as none (<1 mm), small (≥1 mm and <4 mm), and large (≥4 mm), no significant differences were seen in rates of hearing preservation. Using multivariate linear regression models adjusting for patient age, sex, tumor nerve of origin, neurofibromatosis type II status, and preoperative PTA and WRS, superior vestibular nerve tumor origin but not increasing fundal fluid size was associated with preserved postoperative PTA or WRS.Presence or size of CSF fluid cap may

2018 Otology and Neurotology

202. Endoscopic endonasal resection of epidermoid cysts involving the ventral cranial base. Full Text available with Trip Pro

Endoscopic endonasal resection of epidermoid cysts involving the ventral cranial base. OBJECTIVEEpidermoid cysts (ECs) commonly extend to involve the ventral cisterns of the cranial base. When present, symptoms arise due to progressive mass effect on the brainstem and adjacent cranial nerves. Historically, a variety of open microsurgical approaches have been used for resection of ECs in this intricate region. In recent years, the endoscopic endonasal approach (EEA) has been proposed (...) as an alternative corridor that avoids crossing the plane of the cranial nerves. To date, there is a paucity of data in the literature regarding the safety and efficacy of the EEA in the treatment of ECs of the ventral cranial base.METHODSThe authors reviewed a prospectively acquired database of EEAs for resection of ECs over 8 years at Weill Cornell, NewYork-Presbyterian Hospital. All procedures were performed by the senior authors. Standardized clinical and radiological parameters were assessed before

2018 Journal of Neurosurgery

203. A novel and safe approach: middle cranial approach for laparoscopic right hemicolon cancer surgery with complete mesocolic excision. (Abstract)

A novel and safe approach: middle cranial approach for laparoscopic right hemicolon cancer surgery with complete mesocolic excision. Mastering right hemicolectomy techniques using laparoscopy in colorectal cancer surgery is very difficult. Although the long-term prognosis of laparoscopic right hemicolectomy (LRH) and complete mesocolic excision is unquestionable, different surgeons have their own opinions on routes of conducting LRH.LRH surgery is very complex due to the upper abdominal (...) anatomical structure and vascular variation. Therefore, it has been considered the most difficult of all colorectal cancer surgeries. Our innovative middle cranial approach (MCA) was developed to avoid unnecessary injuries and minimize the operative time, thereby reducing the patient's hospital stay and improving their short-term prognosis.We compared 90 colon cancer patients who underwent the MCA between January 2016 and January 2017 with 82 patients who underwent the conventional central approach

2018 Surgical endoscopy

204. Cranial ultrasound and neurophysiological testing to predict neurological outcome in infants born very preterm. Full Text available with Trip Pro

of a population of infants born very preterm.A retrospective cohort study was performed in 163 children born before 32 weeks gestational age. We compared the accuracy in predicting adverse neurodevelopmental outcome at the age of 2 years 6 months of early and late cranial ultrasound (CUS), magnetic resonance imaging, somatosensory evoked potentials after stimulation of the posterior tibial nerve, and electroencephalography by calculating positive and negative likelihood ratios.An abnormal early CUS (...) Cranial ultrasound and neurophysiological testing to predict neurological outcome in infants born very preterm. Infants born preterm are at risk of cerebral palsy (CP) and motor or cognitive developmental delay. For clinicians, it is essential to know the relative predictive accuracy of the most commonly used neuroimaging and neurophysiological tests for the early prediction of adverse neurodevelopmental outcome. The aim of this study was to compare the accuracy of these tests in survivors

2018 Developmental Medicine and Child Neurology

205. Characteristics, outcome and treatments with cranial pachymeningitis: A multicenter French retrospective study of 60 patients. Full Text available with Trip Pro

, female/male ratio 0.43). Neurologic signs were present in 59 patients (98%) and consisted of headache in 43 (72%), cranial nerve palsy in 33 (55%), confusion in 10 (17%), seizures in 7 (12%), and focal neurologic signs in 9 (15%). Fever and weight loss were present in 8 (13%) and 13 cases (22%), respectively. Cerebral venous thrombosis was present in 8 cases (13%). Analysis of cerebrospinal fluid showed moderate hyperproteinorachia (median 0.68 g/L; IQR 0.46-3.2) with or without pleiocytosis (...) Characteristics, outcome and treatments with cranial pachymeningitis: A multicenter French retrospective study of 60 patients. The aim of this study was to determine the characteristics, treatment, and outcome according to each etiology of pachymeningitis.We conducted a retrospective multicenter French nationwide study between 2000 and 2016 to describe the characteristics, outcome, and treatment of pachymeningitis.We included 60 patients (median age 55.5 years; interquartile range [IQR] 30-80

2018 Medicine

206. Penetration of the blood-brain barrier by avitinib and its control of intra/extra-cranial disease in non-small cell lung cancer harboring the T790M mutation. (Abstract)

Penetration of the blood-brain barrier by avitinib and its control of intra/extra-cranial disease in non-small cell lung cancer harboring the T790M mutation. Avitinib is an oral, potent, irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor selective for the EGFR T790 M mutation. We report the safety, intra-/extracranial efficacy, and the blood-brain barrier (BBB) penetration rate of avitinib (NCT02330367).Non-small cell lung cancer (NSCLC) patients with the EGFR T790 M (...) ) and 536 days (95%CI: 363.6-708.4), respectively. The median intracranial PFS of seven brain metastases patients was 142 days (95% CI 31.1-252.9). Blood and cerebrospinal fluid analysis of five brain metastases patients showed the BBB penetration rate to be 0.046%-0.146%. The most frequent adverse events were mild and reversible hepatic transaminases elevating (10/16, 62.5%) and diarrhea (4/16, 25.0%).Avitinib is well tolerated and efficacious in T790M-positive patients. Its penetrability to the BBB is weak

2018 Lung Cancer

207. Ultra Long-Term Audiometric Outcomes in the Treatment of Vestibular Schwannoma With the Middle Cranial Fossa Approach. (Abstract)

Ultra Long-Term Audiometric Outcomes in the Treatment of Vestibular Schwannoma With the Middle Cranial Fossa Approach. Define the long-term audiometric outcomes of vestibular schwannomas treated using the middle cranial fossa (MCF) approach.Retrospective records review.University-based tertiary referral center.Patients undergoing treatment of small vestibular schwannomas using the MCF approach.MCF exposure and treatment of small vestibular schwannomas.Demographic and audiometric variables were (...) assessed.Thirteen subjects demonstrated audiometric data for review. The average time between surgery and the most recent audiometric testing was 14 years (range 10-18 yr). The mean baseline pure-tone average (PTA) was 36 dB HL and the most recent PTA was 59 dB HL in the operated ear. The mean baseline PTA was 16 dB HL and the most recent PTA was 37 dB HL in the nonoperated ear. The mean change from baseline to most recent follow-up was a threshold elevation of 22 and 19 dB HL in the operated and nonoperated

2018 Otology and Neurotology

208. CRACKCast 107 – Peripheral Nerve Disorders

= Central Nervous System + Peripheral Nervous System PNS divided into 12 cranial nerves (Remember episode 105?) 31 spinal nerves (8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal). Almost all of these nerves have Sensory, Motor and autonomic function Anatomically / functionally speaking the autonomic nervous system is divided into: Sympathetic (thoracolumbar) component Parasympathetic (craniosacral) component. Note: Autonomic dysfunction may cause systemic abnormalities (e.g., Orthostasis (...) Vasospastic (deep buttock injection) Neoplastic Radiation Idiopathic lumbosacral plexitis Infectious Herpesvirus (sacrococygeal) Herpes simplex 2 Herpes zoster Cytomegalovirus polyradiculopathy (HIV infection) Isolated mononeuropathies (broad categories): Upper extremity Radial nerve Ulnar nerve Median nerve Lower extremity Sciatic nerve Femoral nerve Lateral femoral cutaneous (meralgia paresthetica) Peroneal nerve Tibial nerve Sural nerve Plantar nerve Obturator mononeuropathy [10] What are two other

2017 CandiEM

209. Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based Greater Occipital Nerve Block

around the nerve at the level of the superior nuchal line. Outcome Measures Go to Primary Outcome Measures : Change in Numeric Rating Scale (NRS) Pain Score [ Time Frame: baseline, 4 weeks ] Pain intensity will be assessed using a NRS marked from 0-10 with fixed intervals, with 0=no pain, and 10=worst pain. Secondary Outcome Measures : Change in number of patients with medication overuse [ Time Frame: baseline, 4 weeks ] The subjects will be provided a headache journal to record the number of days (...) Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based Greater Occipital Nerve Block Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based Greater Occipital Nerve Block - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies

2018 Clinical Trials

210. Total Transcanal Endoscopic Facial Nerve Decompression for Traumatic Facial Nerve Palsy Full Text available with Trip Pro

Total Transcanal Endoscopic Facial Nerve Decompression for Traumatic Facial Nerve Palsy A few approaches can be used to decompress traumatic facial nerve paralysis including the middle cranial fossa approach or transmastoid approach depending on the site of injury. In some specific situation of treating traumatic facial nerve palsy whose injured site was confined from the geniculate ganglion to the second genu, transcanal endoscopic approach for facial nerve decompression can be used. We (...) performed two cases of total endoscopic transcanal facial nerve decompression in patients with traumatic facial nerve palsy. After a six month follow-up, both patients showed improvement in facial function by 2 grades according to House-Brackmann grade system. In terms of treatment outcomes, total transcanal endoscopic facial nerve decompression for traumatic facial nerve palsy is an alternative for lesions limited to the tympanic segment I, and has an advantages of being minimally invasive

2018 Yonsei medical journal

211. Delayed Trochlear Nerve Palsy Following Traumatic Subarachnoid Hemorrhage: Usefulness of High-Resolution Three Dimensional Magnetic Resonance Imaging and Unusual Course of the Nerve Full Text available with Trip Pro

Delayed Trochlear Nerve Palsy Following Traumatic Subarachnoid Hemorrhage: Usefulness of High-Resolution Three Dimensional Magnetic Resonance Imaging and Unusual Course of the Nerve Cranial nerve palsies are relatively common after trauma, but trochlear nerve palsy is relatively uncommon. Although traumatic trochlear nerve palsy is easy to diagnose clinically because of extraocular movement disturbances, radiologic evaluations of this condition are difficult to perform because of the nerve's (...) small size. Here, we report the case of a patient with delayed traumatic trochlear nerve palsy associated with a traumatic subarachnoid hemorrhage (SAH) and the related radiological findings, as obtained with high-resolution three-dimensional (3D) magnetic resonance imaging (MRI). A 63-year-old woman was brought to the emergency room after a minor head trauma. Neurologic examinations did not reveal any focal neurologic deficits. Brain computed tomography showed a traumatic SAH at the left ambient

2018 Korean Journal of Neurotrauma

212. The effectiveness and risks of cranial electrical stimulation for the treatment of pain, depression, anxiety, PTSD, and insomnia: a systematic review

The effectiveness and risks of cranial electrical stimulation for the treatment of pain, depression, anxiety, PTSD, and insomnia: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith (...) outcome(s) Example: 1st author, year of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through a descriptive summary. ">Planned approach Example: number of metastases: standardized mean

2017 PROSPERO

213. Solitary Infiltrating Meningioma of the Trochlear Nerve: Case Report Full Text available with Trip Pro

. A review of the literature and discussion of meningiomas infiltrating cranial nerves are included. (...) Solitary Infiltrating Meningioma of the Trochlear Nerve: Case Report We report the case of a solitary meningioma infiltrating the trochlear nerve, the first in a patient without a neurocutaneous disorder or cavernous sinus involvement. The patient presented with diplopia was found to have a focal enhancing mass encompassing the trochlear nerve. Following surgical resection, pathological examination showed meningioma infiltrating the nerve itself, demonstrated on the included pathology images

2018 Journal of neurological surgery reports

214. The association between auditory nerve neurovascular conflict and sudden unilateral sensorineural hearing loss Full Text available with Trip Pro

The association between auditory nerve neurovascular conflict and sudden unilateral sensorineural hearing loss There may be an association between a neurovascular conflict (NVC) of the auditory nerve and unilateral sudden sensorineural hearing loss (SSNHL).Compression of cranial nerves by vascular structures can lead to significant symptomatology that may require surgical decompression. Notable examples are trigeminal neuralgia and hemifacial spasm. Magnetic resonance imaging (MRI) is part (...) of the workup for SSNHL, and it may depict an NVC of the auditory nerve. Here we look into the association between this NVC and unilateral SSNHL.A retrospective analysis was performed on all consecutive patients with unilateral SSNHL who underwent an MRI scan in our medical center. The data collected included age, gender, side and severity of hearing loss, and accompanying complaints. Each MRI scan was reviewed by a neuroradiologist who was unaware of hearing loss laterality. The presence, side, extent

2018 Laryngoscope investigative otolaryngology

215. Growth changes in the anterior and middle cranial bases assessed with cone-beam computed tomography in adolescents. (Abstract)

landmarks.Cone-beam computed tomography images of 10 dry skulls were used to identify useful landmarks from different areas of the anterior and middle cranial bases based on their reliability and accuracy. These selected landmarks were identified in the images of an already available sample of adolescents (n = 60) taken at 2 time points (19 months apart) to assess dimensional changes with growth.The majority of the proposed 3-dimensional landmarks with the exception of the lesser wing of the sphenoid showed (...) Growth changes in the anterior and middle cranial bases assessed with cone-beam computed tomography in adolescents. Initially, cone-beam computed tomography images from dry skulls were used to 3 dimensionally evaluate intrarater and interrater reliabilities and accuracy of selected 3-dimensional landmarks located in the anterior and middle cranial bases. Thereafter, dimensional changes of the anterior and middle cranial bases with growth were evaluated by using the previously selected

2017 American journal of orthodontics and dentofacial orthopedics

216. Brainwave Changes and Cranial Electrotherapy Stimulation

measure will be taken 5 minutes and 10 minutes post the CES session. Each of these brainwave measures will last 30 seconds. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 50 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Diagnostic Official Title: Effects of Cranial Electric Stimulation on Brain Wave Activity: A Pilot Study Actual Study Start Date : May 27, 2016 Actual Primary (...) Completion Date : May 10, 2017 Actual Study Completion Date : May 10, 2017 Arms and Interventions Go to Arm Intervention/treatment Experimental: Brainwave Brainwave analysis after cranial electric stimulation Device: Cranial Electric Stimulation Micro amperage TCDS Outcome Measures Go to Primary Outcome Measures : Quantitative EEG Analysis [ Time Frame: Quantitative EEG collected at baseline (immediately before stimulation), immediately after 20 minutes of stimulation and then 5 and 10 minutes post

2017 Clinical Trials

217. Cranial Electrical Stimulation (CES) as Treatment for Insomnia in Patients With Subacute Stroke

Cranial Electrical Stimulation (CES) as Treatment for Insomnia in Patients With Subacute Stroke Cranial Electrical Stimulation (CES) as Treatment for Insomnia in Patients With Subacute Stroke - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Cranial Electrical Stimulation (CES) as Treatment for Insomnia in Patients With Subacute Stroke The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03344562 Recruitment Status : Recruiting

2017 Clinical Trials

218. Cranial Osteopathic Manipulative Medicine as an Adjunct Treatment for Concussion

Cranial Osteopathic Manipulative Medicine as an Adjunct Treatment for Concussion Cranial Osteopathic Manipulative Medicine as an Adjunct Treatment for Concussion - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding (...) more. Cranial Osteopathic Manipulative Medicine as an Adjunct Treatment for Concussion The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03225599 Recruitment Status : Completed First Posted : July 21, 2017 Last Update Posted : July 21, 2017 Sponsor: Northwell Health Collaborator: University

2017 Clinical Trials

219. Dexmedetomidine Improves Recovery After Cranial Aneurysm Surgery

Dexmedetomidine Improves Recovery After Cranial Aneurysm Surgery Dexmedetomidine Improves Recovery After Cranial Aneurysm Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Dexmedetomidine Improves (...) Recovery After Cranial Aneurysm Surgery (DACA) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03355534 Recruitment Status : Recruiting First Posted : November 28, 2017 Last Update Posted : March 8, 2018 See Sponsor: Zhihong

2017 Clinical Trials

220. Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors

Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning (...) You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider

2017 Clinical Trials

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