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Cough fracture

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103. Palliative Care for Adults

• Admission from long-term care facility or medical foster home • Elderly patient, cognitively impaired, with acute hip fracture • Metastatic or locally advanced incurable cancer • Chronic home oxygen use • Out-of-hospital cardiac arrest • Current or past hospice program enrollee • Limited social support (e.g., family stress, chronic mental illness) • No history of completing an advance care planning discussion /document a Primary Criteria are global indicators that represent the minimum that hospitals

2020 Institute for Clinical Systems Improvement

104. Sofosbuvir/velpatasvir/voxilaprevir (chronic hepatitis C) - Addendum to Commission A17-35

spasms 1 (2.0) 2 (5.0) Nervous system disorders 9 (18.4) 9 (22.5) Headache 9 (18.4) 5 (12.5) Psychiatric disorders 2 (4.1) 3 (7.5) Respiratory, thoracic and mediastinal disorders 3 (6.1) 1 (2.5) Cough 2 (4.1) 0 (0) Vascular disorders 2 (4.1) 0 (0) a: MedDRA version 19.0. AE: adverse event; MedDRA: Medical Dictionary for Regulatory Activities; n: number of patients with (at least one) event; N: number of analysed patients; PT: Preferred Term; RCT: randomized controlled trial; SOC: System Organ Class (...) ) Hepatobiliary disorders 1 (2.0) 0 (0) Cholelithiasis 1 (2.0) 0 (0) Infections and infestations 1 (2.0) 0 (0) Perineal abscess 1 (2.0) 0 (0) Injury, poisoning and procedural complications 0 (0) 1 (2.5) Multiple fractures 0 (0) 1 (2.5) Road traffic accident 0 (0) 1 (2.5) Musculoskeletal and connective tissue disorders 0 (0) 1 (2.5) Myositis 0 (0) 1 (2.5) Psychiatric disorders 0 (0) 1 (2.5) Suicide attempt 0 (0) 1 (2.5) Respiratory, thoracic and mediastinal disorders 1 (2.0) 0 (0) Asthma 1 (2.0) 0 (0

2018 Institute for Quality and Efficiency in Healthcare (IQWiG)

105. Overview of musculoskeletal pain

of prior fragility fracture or low bone-mass density, which is defined as a T-score <-2.5. Screening is based on individual risk factors, including older age, female sex, maternal history of fragility fractures/osteoporosis, post-menopausal, low BMI, and tobacco use. Patients may report sudden back pain from atraumatic activities such as standing from a seated position, bending forward, or coughing and sneezing. Pain is characteristically exacerbated by movement. Worsening pain over weeks to months (...) /jama/fullarticle/197628 Related conditions Condition Description Chronic fibrosing condition characterised by insidious, progressive, and severe restriction of both active and passive shoulder range of motion. Many patients experience shoulder pain, but shoulder pain is not an essential component of adhesive capsulitis. Although other fractures around and including the ankle can occur (such as distal tibial plafond fractures

2018 BMJ Best Practice

106. Pulmonary embolism

. 1989 Mar;95(3):498-502. Venous thromboembolic disease is the preferred term to describe the spectrum of disease beginning with the risk factors of Virchow's triad, progressing to deep venous thrombosis, and resulting in life-threatening PE. History and exam presence of risk factors chest pain dyspnoea tachypnoea presyncope or syncope hypotension (systolic BP <90 mmHg) feeling of apprehension cough tachycardia fever unilateral swelling (...) /tenderness of calf haemoptysis elevated jugular venous pressure sternal heave accentuated pulmonary component of S2 increasing age diagnosis of deep vein thrombosis (DVT) obesity (BMI ≥29 kg/m²) surgery within the last 2 months bed rest >5 days previous venous thromboembolic event family history of venous thromboembolism (VTE) active malignancy cigarette smoking chronic obstructive pulmonary disease (COPD) recent trauma or fracture congestive heart failure (CHF) central venous catheterisation pregnancy

2018 BMJ Best Practice

107. Non-small cell lung cancer

are cough, chest pain, haemoptysis, dyspnoea, and weight loss. A suspicious lung mass can be biopsied during bronchoscopy or using CT guidance. Staging studies (i.e., CT, PET, mediastinal sampling) are required to determine extent of local or regional disease and to evaluate for metastases. Treatment depends on stage of disease, histological subtype, molecular genotype, and patient comorbidities. Surgery, radiotherapy, and chemotherapy are the most common modalities, but molecular-targeted therapy (...) :// (last accessed 14 September 2017). There are 3 main types of NSCLC (adenocarcinoma, squamous cell carcinoma, and large cell carcinoma) and these are grouped into further subtypes. History and exam presence of risk factors cough dyspnoea haemoptysis chest and/or shoulder pain weight loss male sex fatigue pulmonary examination abnormalities hoarseness confusion personality changes nausea and vomiting headache dysphagia bone pain

2018 BMJ Best Practice

108. Small cell lung cancer

Organization classification of lung tumours. Eur Respir J. 2001;18:1059-1068. History and exam presence of risk factors cough dyspnoea haemoptysis chest pain weight loss age 65 to 70 years male sex fatigue pulmonary examination abnormalities hoarseness confusion personality changes nausea and vomiting headache dysphagia bone pain and/or fractures seizures cervical or supraclavicular (...) Small cell lung cancer Small cell lung cancer - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Small cell lung cancer Last reviewed: February 2019 Last updated: February 2018 Summary Small cell lung cancer (SCLC) is an aggressive malignancy. Approximately two-thirds of patients have evidence of distant metastasis at presentation. It primarily develops in older adult smokers. Most common presenting symptoms are cough

2018 BMJ Best Practice

109. Epistaxis

of the second branch of the trigeminal nerve dry weather and low humidity oxygen dependence septal deviation nasal and other facial fracture other nasal trauma nasal foreign body rhinitis nasal polyp environmental irritants topical nasal drugs primary coagulopathy (e.g., haemophilia) acquired coagulopathy (e.g., use of aspirin, anticoagulant, NSAIDs) familial hereditary haemorrhagic telangiectasia barotrauma ulceration secondary to infection (e.g., herpes zoster, or bacterial infection) forceful coughing

2018 BMJ Best Practice

110. Prospective, randomized comparison of continuous thoracic epidural and thoracic paravertebral infusion in patients with unilateral multiple fractured ribs--a pilot study (Abstract)

, it has never been compared with TEA in terms of efficacy and outcome in patients with fractured ribs.Thirty adult patients of either sex, having three or more unilateral fractured ribs, were randomized to receive continuous bupivacaine infusion through either thoracic epidural or thoracic paravertebral catheter. Visual Analog Scale scores at rest and on coughing, respiratory rate, peak expiratory flow rate, and PaO2/FIO2 ratio were measured before and after administration of block at regular (...) Prospective, randomized comparison of continuous thoracic epidural and thoracic paravertebral infusion in patients with unilateral multiple fractured ribs--a pilot study Thoracic epidural analgesia (TEA), a commonly used analgesic technique in patients with multiple fractured ribs, is technically demanding and associated with certain side effects or complications. Thoracic paravertebral block (TPVB) is a simple and effective method of providing continuous pain relief in these patients. However

2009 EvidenceUpdates Controlled trial quality: uncertain

112. Corticosteroids for treatment of sore throat Full Text available with Trip Pro

. Some patients with sore throat also experience headache, fever, muscle stiffness, cough, and general malaise. Acute sore throat is common, but only a minority of patients will visit their general practitioner. A survey reported that the main reasons are to establish the cause of the symptoms, obtain pain relief, and to gain information on the course of the disease. Data from Dutch and Flemish primary care databases show that, for every 1000 consecutive patients consulting a general practitioner, 50 (...) quality evidence) The panel also considered evidence from observational studies that used higher doses of steroids. A large retrospective US cohort study of private insurance claims assessed adverse events in 327 452 adults who received an outpatient prescription of corticosteroids. There was a small absolute increase in the rate of sepsis, venous thromboembolism, and fracture in the first 30 days (GRADE low quality evidence, due to suboptimal verification of diagnosis in large databases

2017 BMJ Rapid Recommendations

117. WHO Guidelines for the pharmacological and radiotherapeutic management of cancer pain in adults and adolescents

infiltration or destruction of brachial plexus Central Injury to central nervous system Spinal cord compression by tumour Mixed Peripheral and central injury Central sensitization due to unrelieved peripheral neuropathic pain Sympathetically maintained Dysfunction of sympathetic system Chronic regional pain syndrome following fracture or other trauma16 WHO GUIDELINES FOR THE PHARMACOLOGICAL AND RADIOTHERAPEUTIC MANAGEMENT OF CANCER PAIN IN ADULTS AND ADOLESCENTS WHO GUIDELINES FOR THE PHARMACOLOGICAL

2019 World Health Organisation Guidelines

119. BTS/SIGN British Guideline on the Management of Asthma

and asymptomatic • symptoms of wheeze, cough, breathlessness and chest tightness that vary over time • recorded observation of wheeze heard by a healthcare professional • personal/family history of other atopic conditions (in particular, atopic eczema/dermatitis, allergic rhinitis) • no symptoms/signs to suggest alternative diagnoses. ? In patients with a high probability of asthma: • record the patient as likely to have asthma and commence a carefully monitored initiation of treatment (typically six weeks (...) to consider in an initial structured clinical assessment Episodic symptoms (see sections 3.2.1 and 3.2.2) 13, 18, 19, 21, 22 62, 73, 74 More than one of the symptoms of wheeze, breathlessness, chest tightness and cough occurring in episodes with periods of no (or minimal) symptoms between episodes. Note that this excludes cough as an isolated symptom in children. 75 For example: • a documented history of acute attacks of wheeze, triggered by viral infection or allergen exposure with symptomatic

2019 British Thoracic Society

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