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81. Psychological profile of individuals presenting with chronic cough (PubMed)

Psychological profile of individuals presenting with chronic cough Chronic refractory cough (CRC) is a common problem in respiratory clinics. Adverse effects on quality of life are documented in the literature, but relatively little is known about the underlying psychological factors in this patient population. We aimed to investigate the association of psychological factors with chronic cough, comparing CRC to explained cough and non-cough groups. 67 patients attending a specialist cough (...) clinic (CRC, n=25; explained cough, n=42) and 22 non-cough individuals participated. All participants completed the Hospital Anxiety & Depression Scale, Big Five Inventory (Personality), Chalder Fatigue Scale and Patient Health Questionnaire-15. Cough patients also completed the Illness Perception Questionnaire-Revised. Appropriate statistical analyses were used to compare participant groups. Chronic refractory coughers displayed significantly higher levels of anxiety, depression, fatigue and somatic

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2017 ERJ open research

82. Computational Modelling of Cough Function and Airway Penetrant Behavior in Patients with Disorders of Laryngeal Function (PubMed)

Computational Modelling of Cough Function and Airway Penetrant Behavior in Patients with Disorders of Laryngeal Function Patients with laryngeal disorders often exhibit changes to cough function contributing to aspiration episodes. Two primary cough variables (peak cough flow: PCF and compression phase duration: CPD) were examined within a biomechanical model to determine their impact on characteristics that impact airway compromise.Computational study.A Computational Fluid Dynamics (CFD (...) ) technique was used to simulate fluid flow within an upper airway model reconstructed from patient CT images. The model utilized a finite-volume numerical scheme to simulate cough-induced airflow, allowing for turbulent particle interaction, collision, and break-up. Liquid penetrants at 8 anatomical release locations were tracked during the simulated cough. Cough flow velocity was computed for a base case and four simulated cases. Airway clearance was evaluated through assessment of the fate of particles

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2017 Laryngoscope investigative otolaryngology

83. Are inhaled steroids effective for a postviral cough?

Are inhaled steroids effective for a postviral cough? Are inhaled steroids effective for a postviral cough? Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Are inhaled steroids effective for a postviral cough? View/ Open Date 2015-03 Contributor Format Metadata Abstract Q: Are inhaled steroids effective for a postviral (...) cough? Evidence-based answer: No. Inhaled corticosteroids (ICS) don’t improve postviral cough in adults with subacute (3-8 weeks) or chronic (>8 weeks) cough, adolescents with a history of asthma but without recent asthma activity, or children with a history of episodic viral wheezing without asthma (strength of recommendation [SOR]: B, preponderance of small randomized controlled trials [RCTs]). URI Citation Journal of Family Practice, 64(3) 2015: 189. Rights OpenAccess. This work is licensed under

2015 Clinical Inquiries

84. Are inhaled steroids effective for a postviral cough?

Are inhaled steroids effective for a postviral cough? Are inhaled steroids effective for a postviral cough? Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Are inhaled steroids effective for a postviral cough? View/ Open Date 2015-03 Contributor Format Metadata Abstract Q: Are inhaled steroids effective for a postviral (...) cough? Evidence-based answer: No. Inhaled corticosteroids (ICS) don’t improve postviral cough in adults with subacute (3-8 weeks) or chronic (>8 weeks) cough, adolescents with a history of asthma but without recent asthma activity, or children with a history of episodic viral wheezing without asthma (strength of recommendation [SOR]: B, preponderance of small randomized controlled trials [RCTs]). URI Citation Journal of Family Practice, 64(3) 2015: 189. Rights OpenAccess. This work is licensed under

2015 Clinical Inquiries

85. The efficacy of codeine antitussive agents versus placebo in symptomatic treatment of cough: a systematic review and meta-analysis of randomized controlled trials

The efficacy of codeine antitussive agents versus placebo in symptomatic treatment of cough: a systematic review and meta-analysis of randomized controlled trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability

2019 PROSPERO

86. Efficacy of histamine antagonist antitussive agents versus placebo in symptomatic treatment of cough: a systematic review and meta-analysis of randomized controlled trials

Efficacy of histamine antagonist antitussive agents versus placebo in symptomatic treatment of cough: a systematic review and meta-analysis of randomized controlled trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability

2019 PROSPERO

87. A traditional chinese patent medicine - suhuangzhike capsule for cough variant asthma in adults : a systematic review and meta-analysis of randomised controlled trials

A traditional chinese patent medicine - suhuangzhike capsule for cough variant asthma in adults : a systematic review and meta-analysis of randomised controlled trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability

2019 PROSPERO

88. Does respiratory muscle training alter respiratory function, cough and/or physical capacity in children/adults with neuromuscular disease? A systematic review

Does respiratory muscle training alter respiratory function, cough and/or physical capacity in children/adults with neuromuscular disease? A systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content

2019 PROSPERO

89. Cough augmentation techniques for people with chronic neuromuscular disorders [Cochrane protocol]

Cough augmentation techniques for people with chronic neuromuscular disorders [Cochrane protocol] Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external

2019 PROSPERO

90. Efficacy and safety of eucalyptus for relief of cough symptoms: a systematic review and meta-analysis

Efficacy and safety of eucalyptus for relief of cough symptoms: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files

2019 PROSPERO

91. The course of lung inflation alters the central pattern of tracheobronchial cough in cat – the evidence for volume feedback during cough (PubMed)

The course of lung inflation alters the central pattern of tracheobronchial cough in cat – the evidence for volume feedback during cough The effect of volume-related feedback and output airflow resistance on the cough motor pattern was studied in 17 pentobarbital anesthetized spontaneously-breathing cats. Lung inflation during tracheobronchial cough was ventilator controlled and triggered by the diaphragm electromyographic (EMG) signal. Altered lung inflations during cough resulted (...) in modified cough motor drive and temporal features of coughing. When tidal volume was delivered (via the ventilator) there was a significant increase in the inspiratory and expiratory cough drive (esophageal pressures and EMG amplitudes), inspiratory phase duration (CTI), total cough cycle duration, and the duration of all cough related EMGs (Tactive). When the cough volume was delivered (via the ventilator) during the first half of inspiratory period (at CTI/2-early over inflation

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2016 Respiratory physiology & neurobiology

92. Alternative Measurements of Cough Pressure and Effects of Epidural Anaesthesia on Cough Pressure

Alternative Measurements of Cough Pressure and Effects of Epidural Anaesthesia on Cough Pressure Alternative Measurements of Cough Pressure and Effects of Epidural Anaesthesia on Cough Pressure - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Alternative Measurements of Cough Pressure and Effects of Epidural Anaesthesia on Cough Pressure (ESPIRATOS) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02957045 Recruitment Status : Completed First Posted : November 7, 2016 Last Update Posted : November 7, 2016

2016 Clinical Trials

93. Coughing correlates: insights into an innovative study using cough peak expiratory flow to predict extubation failure (PubMed)

Coughing correlates: insights into an innovative study using cough peak expiratory flow to predict extubation failure 27919282 2018 01 09 2018 12 02 1466-609X 20 1 2016 12 06 Critical care (London, England) Crit Care Coughing correlates: insights into an innovative study using cough peak expiratory flow to predict extubation failure. 394 Jiang Chuan C 0000-0002-1601-6854 Department of Medicine, Division of Nephrology, Northwell Health, Lenox Hill Hospital, Nephrology Division, 100 East 77th (...) Street 3rd Floor, New York, NY, 11075-1850, USA. cjiang@northwell.edu. Esquinas Antonio M AM Intensive Care and Non-invasive Ventilatory Unit, Hospital Morales Meseguer, Murcia, Spain. Mina Bushra B Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwell Health, Lenox Hill Hospital, New York, NY, 10065, USA. eng Letter Comment 2016 12 06 England Crit Care 9801902 1364-8535 IM Crit Care. 2016 Oct 7;20(1):316 27716405 Airway Extubation Cough Humans Pulmonary Disease, Chronic

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2016 Critical Care

94. Cough frequency monitors: can they discriminate patient from environmental coughs? (PubMed)

Cough frequency monitors: can they discriminate patient from environmental coughs? Objective cough frequency measurements are increasingly applied in clinical research. Technological advances enable automated detection and counting of cough events from sound recordings of many hours' duration. A possible limitation of sound-based cough frequency measurement is the contamination of recordings by environmental coughs (coughs from persons other than the patient). This study aimed to investigate (...) the accuracy of a sound-based cough monitor for detecting and discriminating patient cough from environmental cough.As part of a stroke trial (ISRCTN40298220), patients on a hospital ward underwent 15-minute recordings using the Leicester Cough Monitor (LCM), a sound-based cough monitor ('semi-automated counts'). Participants and other persons in the environment were prompted to cough. An observer present in the room recorded the number of patient and environmental coughs ('live counts'). LCM counts were

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2016 Journal of thoracic disease

95. A Longitudinal Study of Association between Heavy Metals and Itchy Eyes, Coughing in Chronic Cough Patients: Related with Non-Immunoglobulin E Mediated Mechanism (PubMed)

A Longitudinal Study of Association between Heavy Metals and Itchy Eyes, Coughing in Chronic Cough Patients: Related with Non-Immunoglobulin E Mediated Mechanism The association between heavy metals exposure and respiratory diseases or allergic sensitization showing high serum immunoglobulin E (IgE) has been suggested. However, previous findings have been inconsistent and the mechanisms responsible remain unclear. We evaluated heavy metal exposure and its association with coughing, itchy eyes (...) in chronic cough patients with different IgE levels. Ninety outpatients in Kanazawa University Hospital were recruited between January-June 2011. Subjects whose total IgE measured by radioimmunosorbent test were asked to record their daily symptoms. We collected daily total suspended particles (TSP) from which concentrations of calcium (Ca), cadmium (Cd), chromium (Cr), iron (Fe), manganese (Mn), nickel (Ni), and lead (Pb) were determined then divided into high and low level groups. Generalized

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2016 International journal of environmental research and public health

96. Heterogeneity of cough neurobiology: Clinical implications. (PubMed)

Heterogeneity of cough neurobiology: Clinical implications. Cough is an important protective mechanism for clearing the airways but becomes a troublesome, and often difficult to treat, symptom in respiratory disease. Although cough can be produced as a reflex in response to the presence of irritants within the airways, emerging research demonstrates an unappreciated complexity in the peripheral and central neural systems that regulate cough. This complexity includes multiple primary sensory (...) neurons that can induce or facilitate reflex coughing, different ascending central circuits in the brain that contribute to cough sensory discrimination and the perception of the urge-to-cough, and several descending brain systems for inducing, facilitating and inhibiting cough responses. Consequently, the mechanisms responsible for cough becoming dysregulated in disease are not likely homogeneous across all patients with chronic cough. The available data suggests that changes in primary sensory

2019 Pulmonary Pharmacology & Therapeutics

97. Cough in pulmonary tuberculosis: Existing knowledge and general insights. (PubMed)

Cough in pulmonary tuberculosis: Existing knowledge and general insights. Cough is a prominent symptom of pulmonary tuberculosis (TB), one of the oldest and most prevalent infectious diseases. Coughing probably has a pivotal role in transmission of the causative organism Mycobacterium tuberculosis. Despite this, little research to date has addressed this subject. Current knowledge of the mechanisms of cough in TB and how exactly coughing patterns predict infectiousness is scant (...) , but this is changing. This overview summarises the existing evidence for the infectiousness of cough in TB, clinical correlates, and possible causes of cough in TB. Potential unique characteristics of cough in the disease are discussed, as is treatment and the subjective awareness of coughing in the disease.Copyright © 2019 Elsevier Ltd. All rights reserved.

2019 Pulmonary Pharmacology & Therapeutics

98. Development and validation of the COugh Assessment Test (COAT). (PubMed)

Development and validation of the COugh Assessment Test (COAT). A cough-specific quality-of-life questionnaire is recommended to assess the impact of cough; however, a simple instrument to quantify cough is required for everyday clinical practice. This study was aimed to develop a short patient-completed questionnaire (COugh Assessment Test, COAT).The COAT was developed and validated by comparison with the Korean version of Leicester Cough Questionnaire (K-LCQ) and cough numeric rating scale (...) (NRS, 0-10, 11-point scale) for chronic cough patients.Item selection identified five items regarding cough frequency, daily activity, sleep disturbance, fatigue and cough hypersensitivity (0-4 scaling of items, 0-20 score range) through reliability test cohort (n = 78). Test-retest reliability was strong (intra-class correlation coefficient = 0.88). The final COAT was compared with K-LCQ and cough NRS in a validation cohort (n = 323). In Rasch analysis, COAT fitted well to a unidimensional model

2019 Respirology

99. Pharmacological methods for reducing coughing on emergence from elective surgery after general anesthesia with endotracheal intubation: protocol for a systematic review of common medications and network meta-analysis. (PubMed)

Pharmacological methods for reducing coughing on emergence from elective surgery after general anesthesia with endotracheal intubation: protocol for a systematic review of common medications and network meta-analysis. Emergence coughing and bucking, secondary to endotracheal tube stimulation of the tracheal mucosa, frequently occurs after the general anesthetic recedes. Besides general unpleasantness, coughing has important physiological sequelae that may be detrimental to the postoperative (...) patient. Multiple pharmacological strategies have been published, but prior systematic reviews on this topic have neither been comprehensive enough in their literature or medication search, nor provided us the answer regarding what the best pharmacological method is to prevent or minimize peri-extubation coughing. Our systematic review and network meta-analysis' primary objective is to determine the relative efficacies of different pharmacological methods on decreasing coughing (none to mild compared

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2019 Systematic reviews

100. Prevalence of nocturnal cough in asthma and its potential as a marker for asthma control (MAC) in combination with sleep quality: protocol of a smartphone-based, multicentre, longitudinal observational study with two stages. (PubMed)

Prevalence of nocturnal cough in asthma and its potential as a marker for asthma control (MAC) in combination with sleep quality: protocol of a smartphone-based, multicentre, longitudinal observational study with two stages. Nocturnal cough is a burdensome asthma symptom. However, knowledge about the prevalence of nocturnal cough in asthma is limited. Furthermore, prior research has shown that nocturnal cough and impaired sleep quality are associated with asthma control, but the association (...) between these two symptoms remains unclear. This study further investigates the potential of these symptoms as markers for asthma control and the accuracy of automated, smartphone-based passive monitoring for nocturnal cough detection and sleep quality assessment.The study is a multicentre, longitudinal observational study with two stages. Sensor and questionnaire data of 94 individuals with asthma will be recorded for 28 nights by means of a smartphone. On the first and the last study day

2019 BMJ open

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