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22601. Bordetella pertussis isolation in general practice: 1977-79 whooping cough epidemic in West Glamorgan. Full Text available with Trip Pro

Bordetella pertussis isolation in general practice: 1977-79 whooping cough epidemic in West Glamorgan. Some of the factors influencing the isolation rate of Bordetella pertussis during a whooping cough epidemic in West Glamorgan, Wales, are reported. The organism was isolated from 39% of patients with clinical whooping cough, pernasal swabbing being much more successful than cough plates. Isolation rates were increased in the non-immunized, particularly in the first year of life. Erythromycin

1983 The Journal of hygiene

22602. Whooping cough--a study of severity in hospital cases. Full Text available with Trip Pro

Whooping cough--a study of severity in hospital cases. In an attempt to determine the clinical severity and prognosis of children admitted to hospital with whooping cough, 127 patients were studied prospectively during a 12-month period. Clinical and laboratory criteria were used and the impression gained was that most cases were mild, although 3 children were dangerously ill and at least 30% had symptoms lasting 2 months or longer. There were no deaths, and no permanent sequelae were noted (...) . The mean age of patients was higher than in other series, which might have accounted for the fairly low severity. Although there was some evidence of a decline in severity and mortality, whooping cough is still an unpleasant and protracted illness.

1981 Archives of Disease in Childhood

22603. Psychogenic cough. Full Text available with Trip Pro

Psychogenic cough. Psychogenic cough is croupy and explosive, never occurs during sleep, and is not affected by antitussive drugs. Physical and radiographic examinations of the respiratory tract and microbiological investigations are normal. Bronchial asthma manifested as chronic cough should be excluded in each patient by lung function testing.

1983 Archives of Disease in Childhood

22604. Is cough as effective as chest physiotherapy in the removal of excessive tracheobronchial secretions? Full Text available with Trip Pro

Is cough as effective as chest physiotherapy in the removal of excessive tracheobronchial secretions? The relative value of chest physiotherapy (including cough) and cough alone for the removal of excessive tracheobronchial secretions has been assessed in six patients with stable chronic obstructive lung disease. After labelling with inhaled radioactive tracer particles, clearance of secretions from selected central and peripheral lung regions was followed with a gamma camera linked (...) to a computer. Cough alone and chest physiotherapy (including cough) were equally effective in the enhancement of central lung clearance. Physiotherapy but not cough along accelerated peripheral lung clearance (p less than 0.05). Sputum yield was greater during physiotherapy than during cough (p less than 0.05). These findings confirm the value of chest physiotherapy and high-light the limitation of cough in patients with excessive tracheobronchial secretion and impaired mucociliary clearance.

1981 Thorax

22605. Whooping cough in nursery school children Full Text available with Trip Pro

Whooping cough in nursery school children This paper describes an outbreak of whooping cough in a nursery school during a large epidemic in West Glamorgan. Explosive outbreaks of whooping cough occurred in nursery schools in the area when the majority of children had not been vaccinated. It is recommended that the period of quarantine for whooping cough should be four weeks.

1981 The Journal of the Royal College of General Practitioners

22606. The whooping-cough immunisation controversy. Full Text available with Trip Pro

The whooping-cough immunisation controversy. 7271295 1981 10 25 2016 11 23 1468-2044 56 8 1981 Aug Archives of disease in childhood Arch. Dis. Child. The whooping-cough immunisation controversy. 577-80 Robinson R J RJ eng Journal Article England Arch Dis Child 0372434 0003-9888 0 Pertussis Vaccine AIM E IM Child, Preschool Compensation and Redress Disease Outbreaks Financing, Government Humans Immunization adverse effects Legislation, Medical Nervous System Diseases etiology Pertussis Vaccine (...) adverse effects Risk Risk Assessment Time Factors United Kingdom Whooping Cough epidemiology prevention & control 14474 Health Care and Public Health National Childhood Encephalopathy Study Vaccine Damage Payments Act KIE BoB Subject Heading: immunization 5 refs. 1981 8 1 1981 8 1 0 1 1981 8 1 0 0 ppublish 7271295 PMC1627257

1981 Archives of Disease in Childhood

22607. Antibiotics for whooping cough. Full Text available with Trip Pro

Antibiotics for whooping cough. 7370699 1980 07 26 2018 11 13 0007-1447 280 6217 1980 Mar 22 British medical journal Br Med J Antibiotics for whooping cough. 864 Jenkinson D D eng Letter England Br Med J 0372673 0007-1447 63937KV33D Erythromycin 7C782967RD Ampicillin AIM IM Ampicillin therapeutic use Erythromycin therapeutic use Humans Infant Whooping Cough drug therapy 1980 3 22 1980 3 22 0 1 1980 3 22 0 0 ppublish 7370699 PMC1600965 J Pediatr. 1969 Nov;75(5):768-81 4310467

1980 British medical journal

22608. Whooping cough? Full Text available with Trip Pro

Whooping cough? 7388720 1980 09 26 2008 11 20 0008-4409 122 11 1980 Jun 07 Canadian Medical Association journal Can Med Assoc J Whooping cough? 1238 Adey A B AB eng Letter Canada Can Med Assoc J 0414110 0008-4409 AIM IM Humans Whooping Cough diagnosis prevention & control 1980 6 7 1980 6 7 0 1 1980 6 7 0 0 ppublish 7388720 PMC1802026

1980 Canadian Medical Association Journal

22609. Altitude treatment for whooping cough. Full Text available with Trip Pro

Altitude treatment for whooping cough. 2043838 1991 07 16 2008 11 20 0959-8138 302 6786 1991 May 18 BMJ (Clinical research ed.) BMJ Altitude treatment for whooping cough. 1212 Casey P A PA eng Letter England BMJ 8900488 0959-8138 AIM IM BMJ. 1991 Jul 6;303(6793):58 1859970 Aircraft Altitude Child Humans Whooping Cough therapy 1991 5 18 1991 5 18 0 1 1991 5 18 0 0 ppublish 2043838 PMC1669876

1991 BMJ : British Medical Journal

22610. Altitude treatment for whooping cough. Full Text available with Trip Pro

Altitude treatment for whooping cough. 1859970 1991 09 05 2018 11 13 0959-8138 303 6793 1991 Jul 06 BMJ (Clinical research ed.) BMJ Altitude treatment for whooping cough. 58 Hall D D eng Comment Letter England BMJ 8900488 0959-8138 AIM IM BMJ. 1991 May 18;302(6786):1212 2043838 Altitude Humans Whooping Cough therapy 1991 7 6 1991 7 6 0 1 1991 7 6 0 0 ppublish 1859970 PMC1670293 BMJ. 1991 May 18;302(6786):1212 2043838

1991 BMJ : British Medical Journal

22611. Morbidity in whooping cough and measles. Full Text available with Trip Pro

Morbidity in whooping cough and measles. Parents of 99 children who were admitted to hospital with whooping cough or measles, and of 50 children with whooping cough or measles who were nursed at home, were interviewed to determine the extent of morbidity and its effects on the family. Children admitted with whooping cough or measles spent a mean of 12.6 and 5.8 days in hospital, respectively. Time to full recovery was 13.7 and 2.1 weeks, respectively. Over a third of the children who were

1989 Archives of Disease in Childhood

22612. Recombinant human enkephalinase (neutral endopeptidase) prevents cough induced by tachykinins in awake guinea pigs. Full Text available with Trip Pro

Recombinant human enkephalinase (neutral endopeptidase) prevents cough induced by tachykinins in awake guinea pigs. To determine whether recombinant enkephalinase (neutral endopeptidase, EC 3.4.24.11) prevents cough induced by exogenously applied and endogenously released neuropeptides, we measured cough responses to aerosolized solutions of substance P or of capsaicin for 2 min in random-source guinea pigs before or after exposing them to aerosolized recombinant human enkephalinase. Substance (...) P (10(-16) M) increased coughing compared with its vehicle. Enkephalinase (120 micrograms) inhibited cough induced by subsequent exposure to substance P compared with the response to substance P alone, but after further exposure to the enkephalinase inhibitor leucine-thiorphan (10(-5) M), substance P increased cough significantly. Similar results were obtained for capsaicin-induced cough. In pathogen-free guinea pigs, after they inhaled inactive recombinant enkephalinase (33 micrograms

1989 Journal of Clinical Investigation

22613. Respiratory sequelae and lung function after whooping cough in infancy. Full Text available with Trip Pro

Respiratory sequelae and lung function after whooping cough in infancy. The lung function of 31 children, aged 6-13 years, who had whooping cough as infants and 32 control children matched for age, sex, and residence area were compared in a community based cohort study. Family history of obstructive airway disease, smoking habits in the family, atopy, and other background factors examined were similar in the two groups. The ratios of recalled repeated acute respiratory infections did not differ (...) among the groups. Children in the control group were slightly more involved in physical activities. History of obstructive airway disease, findings on chest radiography, and distribution of immunoglobulin concentrations, including IgE, did not differ significantly. Lung function before and after exercise and after inhalation of salbutamol were not different. No impairment of small airways was detected. Our data do not support the hypothesis that whooping cough in itself is a causal factor for later

1990 Archives of Disease in Childhood

22614. Physiology and treatment of cough. Full Text available with Trip Pro

Physiology and treatment of cough. 2203180 1990 10 04 2018 11 13 0040-6376 45 6 1990 Jun Thorax Thorax Physiology and treatment of cough. 425-30 Fuller R W RW Department of Clinical Pharmacology, Royal Postgraduate Medical School, London. Jackson D M DM eng Journal Article Review England Thorax 0417353 0040-6376 IM Cough drug therapy etiology physiopathology Humans Respiratory System innervation physiopathology 64 1990 6 1 1990 6 1 0 1 1990 6 1 0 0 ppublish 2203180 PMC462522 Bull Eur

1990 Thorax

22615. Unusual Complication of ACE Inhibitor-Induced Cough Full Text available with Trip Pro

Unusual Complication of ACE Inhibitor-Induced Cough A cough produced by the administration of the angiotensin-converting enzyme (ACE) inhibitor, captopril, resulted in a case of rectus abdominis hematoma. The author discusses the incidence and pathophysiology of ACE inhibitor-induced cough.

1989 Canadian Family Physician

22616. Nonprescription cough and cold remedies. Full Text available with Trip Pro

Nonprescription cough and cold remedies. 2322907 1990 05 17 2008 11 21 0820-3946 142 8 1990 Apr 15 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Nonprescription cough and cold remedies. 801 Rathbun F J FJ eng Letter Canada CMAJ 9711805 0820-3946 0 Nonprescription Drugs AIM IM Common Cold drug therapy Cough drug therapy Drug Labeling Humans Nonprescription Drugs Ontario Safety 1990 4 15 1990 4 15 0 1 1990 4 15 0 0 ppublish 2322907 PMC1451908

1990 CMAJ: Canadian Medical Association Journal

22617. Nonprescription cough and cold remedies. Full Text available with Trip Pro

Nonprescription cough and cold remedies. 1974165 1990 09 11 2016 08 15 0820-3946 143 3 1990 Aug 01 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Nonprescription cough and cold remedies. 175 Lexchin J J eng Letter Canada CMAJ 9711805 0820-3946 0 Histamine H1 Antagonists 0 Nonprescription Drugs AIM IM Common Cold drug therapy Histamine H1 Antagonists therapeutic use Humans Nonprescription Drugs 1990 8 1 1990 8 1 0 1 1990 8 1 0 0 ppublish 1974165

1990 CMAJ: Canadian Medical Association Journal

22618. Chronic cough and gastroesophageal reflux. Full Text available with Trip Pro

Chronic cough and gastroesophageal reflux. We reviewed the charts of 20 patients with chronic cough of unknown cause who had been referred to a tertiary care respiratory centre from 1980 to 1984 to determine whether gastroesophageal reflux (GER) was a contributing factor. Fifteen of the patients complained of symptoms suggestive of GER: radiologic investigation of the upper gastrointestinal tract revealed hiatus hernia and GER in four, hiatus hernia alone in three, GER alone in two, decreased (...) and metoclopramide) relieved the chronic cough in 14 of the 20 patients. Of the remaining patients one was lost to follow-up and five had GER confirmed by means of esophagoscopy, esophageal motility testing and long-term intraesophageal pH monitoring; four of the five patients underwent fundoplication and were asymptomatic 3 months after surgery. Antireflux therapy should be considered in patients with chronic cough when other causes have been ruled out, even if there are no GER symptoms. If the treatment fails

1989 CMAJ: Canadian Medical Association Journal

22619. Chronic cough in a hospital population; its relationship to atopy and defects in host defence. Full Text available with Trip Pro

Chronic cough in a hospital population; its relationship to atopy and defects in host defence. The background and aetiology of chronic cough were investigated by comparing 60 children under 6 years with simple cough, 60 children with asthma, and 60 controls. Both cough and asthma were more common in boys and associated with a history of eczema, chest deformity, and skin reactivity to inhaled allergens, but these findings were more prevalent in asthma than cough. House dust mite sensitivity (...) was found in 34 (57%) children with cough, 45 (75%) with asthma, and six (10%) controls. Tests of immunological function showed some high concentrations of IgM in groups with both cough and asthma, but high IgE concentrations, eosinophilia, and lymphocytosis were significant only in asthma. IgG1 and IgG2 concentrations were raised in some children with cough or asthma, but the only low subclass concentrations were of IgG3 observed in the group with cough. Children with simple cough represented

1989 Archives of Disease in Childhood

22620. Undernotification of whooping cough. Full Text available with Trip Pro

Undernotification of whooping cough. 7773065 1995 07 13 2018 11 13 0959-8138 310 6990 1995 May 20 BMJ (Clinical research ed.) BMJ Undernotification of whooping cough. 1331 Evans M R MR eng Comment Letter England BMJ 8900488 0959-8138 AIM IM BMJ. 1995 Feb 4;310(6975):299-302 7866173 Disease Notification England epidemiology Family Practice Female Humans Male Wales epidemiology Whooping Cough epidemiology 1995 5 20 1995 5 20 0 1 1995 5 20 0 0 ppublish 7773065 PMC2549703 Lancet. 1994 Oct 29;344

1995 BMJ : British Medical Journal

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