How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

22,682 results for

Cough

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

181. Comparison of Lidocaine and Atropine on Fentanyl-Induced Cough: A Randomized Controlled Study. (PubMed)

Comparison of Lidocaine and Atropine on Fentanyl-Induced Cough: A Randomized Controlled Study. Fentanyl and atropine are drugs used for analgesia during induction and for premedication, respectively. The aim of this study was to observe the effect of atropine used for premedication on cough developing in association with fentanyl use during anesthesia induction.This was a single-blind, prospective, multi-arm, parallel, randomized clinical trial involving 120 patients between ages 3 and 15 years (...) undergoing general anesthesia. Patients were randomized into three groups: a control group (Group C), an atropine group (Group A), and a lidocaine group (Group L).Incidence of cough was 45% (n = 16) in Group C, 16% (n = 6) in Group A, and 16% in Group L (n = 6) (p = 0.009). Cough was moderate in two cases in Group A and in two in Group L, and mild in all others in these groups. In Group C, cough was mild in seven cases, moderate in six, and severe in two.We determined that premedication with atropine

2018 Journal of investigative surgery : the official journal of the Academy of Surgical Research

182. Implementing Cough Reflex Testing in a Clinical Pathway for Acute Stroke: A Pragmatic Randomised Controlled Trial. (PubMed)

Implementing Cough Reflex Testing in a Clinical Pathway for Acute Stroke: A Pragmatic Randomised Controlled Trial. Silent aspiration is common after stroke and can lead to subsequent pneumonia. While standard bedside dysphagia assessments are ineffective at predicting silent aspiration, cough reflex testing (CRT) has shown promise for identifying patients at risk of silent aspiration. We investigated the impact of CRT on patient and service outcomes when embedded into a clinical pathway. 488

2018 Dysphagia

183. The effects of respiratory muscle training on peak cough flow in patients with Parkinson's disease: a randomized controlled study. (PubMed)

The effects of respiratory muscle training on peak cough flow in patients with Parkinson's disease: a randomized controlled study. To compare the effects of an inspiratory versus and expiratory muscle-training program on voluntary and reflex peak cough flow in patients with Parkinson disease.A randomized controlled study.Home-based training program.In all, 40 participants with diagnosis of Parkinson's disease were initially recruited in the study and randomly allocated to three study groups (...) and a fixed resistance.Spirometric indices, maximum inspiratory pressure, maximum expiratory pressure, and peak cough flow during voluntary and reflex cough were assessed before and at two months after training.The magnitude of increase in maximum expiratory pressure ( d = 1.40) and voluntary peak cough flow ( d = 0.89) was greater for the expiratory muscle-training group in comparison to the control group. Reflex peak cough flow had a moderate effect ( d = 0.27) in the expiratory group in comparison

2018 Clinical rehabilitation

184. Standing Vs Supine; Does it Matter in Cough Stress Testing? (PubMed)

Standing Vs Supine; Does it Matter in Cough Stress Testing? The aim of this study was to compare the sensitivity of cough stress test in the standing versus supine position in the evaluation of incontinent females.We performed a prospective observational study of women with the chief complaint of urinary incontinence (UI) undergoing a provocative cough stress test (CST). Subjects underwent both a standing and a supine CST. Testing order was randomized via block randomization. Cough stress test (...) was performed in a standard method via backfill of 200 mL or until the subject described strong urge. The subjects were asked to cough, and the physician documented urine leakage by direct observation. The gold standard for stress UI diagnosis was a positive CST in either position.Sixty subjects were enrolled, 38 (63%) tested positive on any CST, with 38 (63%) positive on standing compared with 29 (28%) positive on supine testing. Nine women (15%) had positive standing and negative supine testing

2018 Female pelvic medicine & reconstructive surgery

185. Chronic Cough Is Associated With Long Breaks in Esophageal Peristaltic Integrity on High-resolution Manometry (PubMed)

Chronic Cough Is Associated With Long Breaks in Esophageal Peristaltic Integrity on High-resolution Manometry Breaks in the peristaltic contour on esophageal high-resolution manometry (HRM) may be associated with bolus retention in the esophagus. We evaluated the relationship between peristaltic breaks and esophageal symptoms, reflux exposure, and symptom outcomes in a prospective patient cohort.Two hundred and eighteen patients (53.2 ± 0.9 years, 68.3% female) undergoing both pH-impedance (...) testing and HRM over a 5-year period were prospectively evaluated. Demographics, symptom presentation, acid exposure time, symptom association probability, and symptom burden scores were collected. Outcomes were assessed on follow-up using changes in symptom scores. Presence of long breaks (≥ 5 cm) on HRM was assessed by a blinded author. Relationships between breaks, reflux parameters, presenting symptoms, and outcomes were assessed.Patients with long breaks were more likely to have cough

Full Text available with Trip Pro

2018 Journal of neurogastroenterology and motility

186. Unusual cause of sinusitis and cough (PubMed)

Unusual cause of sinusitis and cough 30030254 2019 02 19 2019 03 20 1757-790X 2018 2018 Jul 19 BMJ case reports BMJ Case Rep Unusual cause of sinusitis and cough. bcr-2018-225829 10.1136/bcr-2018-225829 Aldana Grecia G Pulmonary Medicine, MD Anderson Cancer Center, Houston, Texas, USA. Jimenez Carlos A CA Pulmonary Medicine, MD Anderson Cancer Center, Houston, Texas, USA. Moran Cesar C Pathology Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. eng Case Reports (...) Journal Article 2018 07 19 England BMJ Case Rep 101526291 1757-790X 0 PCI 32765 0 Protein Kinase Inhibitors 0 Pyrazoles 0 Pyrimidines IM Biopsy Cough complications etiology Female Humans Leukemia, Lymphocytic, Chronic, B-Cell complications diagnostic imaging drug therapy pathology Lung Neoplasms diagnostic imaging drug therapy secondary Middle Aged Protein Kinase Inhibitors therapeutic use Pyrazoles therapeutic use Pyrimidines therapeutic use Radiography, Thoracic Salvage Therapy methods Sinusitis

Full Text available with Trip Pro

2018 BMJ case reports

187. KAAACI Evidence-Based Clinical Practice Guidelines for Chronic Cough in Adults and Children in Korea (PubMed)

KAAACI Evidence-Based Clinical Practice Guidelines for Chronic Cough in Adults and Children in Korea Chronic cough is common in the community and causes significant morbidity. Several factors may underlie this problem, but comorbid conditions located at sensory nerve endings that regulate the cough reflex, including rhinitis, rhinosinusitis, asthma, eosinophilic bronchitis, and gastroesophageal reflux disease, are considered important. However, chronic cough is frequently non-specific (...) and accompanied by not easily identifiable causes during the initial evaluation. Therefore, there are unmet needs for developing empirical treatment and practical diagnostic approaches that can be applied in primary clinics. Meanwhile, in referral clinics, a considerable proportion of adult patients with chronic cough are unexplained or refractory to conventional treatment. The present clinical practice guidelines aim to address major clinical questions regarding empirical treatment, practical diagnostic

Full Text available with Trip Pro

2018 Allergy, asthma & immunology research

188. The Use of Online Health Forums by Patients With Chronic Cough: Qualitative Study. (PubMed)

The Use of Online Health Forums by Patients With Chronic Cough: Qualitative Study. Online health discussion forums are used by different patient groups for sharing advice and information. Chronic cough is a common problem, and people with chronic cough use online health forums alongside formal medical therapies.The objective of this study was to assess how chronic cough sufferers use online health forums, including the treatment advice they share with one another and the possible clinical uses (...) of online forums in chronic cough.Three open-access health forums were searched for threads related to chronic cough. Identified threads were screened against inclusion and exclusion criteria adapted from the British Thoracic Society (BTS) Guidelines related to chronic cough diagnosis. Included data were subjected to qualitative thematic analysis. All study data were cross-validated by a second author and discrepancies were resolved.In total, 96 threads were included in the analysis, consisting of posts

Full Text available with Trip Pro

2018 Journal of medical Internet research

189. Treating cough due to non-CF and CF bronchiectasis with non-pharmacological airway clearance: CHEST Expert Panel Report. (PubMed)

Treating cough due to non-CF and CF bronchiectasis with non-pharmacological airway clearance: CHEST Expert Panel Report. In bronchiectasis due to cystic fibrosis (CF) and other causes, airway clearance is one of the mainstays of management. We conducted a systematic review on airway clearance by using non-pharmacological methods as recommended by international guidelines to develop recommendations or suggestions to update the 2006 CHEST guideline on cough.The systematic search for evidence (...) examined the question, "Is there evidence of clinically important treatment effects for non-pharmacological therapies in cough treatment for patients with bronchiectasis?" Populations selected were all patients with bronchiectasis due to CF or non-CF bronchiectasis. The interventions explored were the non-pharmacological airway clearance therapies. The comparison populations included those receiving standard therapy and/or placebo. Clinically important outcomes that were explored were exacerbation

Full Text available with Trip Pro

2018 Chest

190. Maternal Vaccination with a Mono-component Pertussis Toxoid Vaccine is Sufficient to Protect Infants in a Baboon Model of Whooping Cough. (PubMed)

Maternal Vaccination with a Mono-component Pertussis Toxoid Vaccine is Sufficient to Protect Infants in a Baboon Model of Whooping Cough. Bordetella pertussis is a human pathogen responsible for serious respiratory illness. The disease is most severe in infants too young to be vaccinated with most hospitalizations and deaths occurring within this age group. The Advisory Committee on Immunization Practices recommended immunization of pregnant women to protect infants from birth until their first

Full Text available with Trip Pro

2018 Journal of Infectious Diseases

191. Speech Therapy in the Management of Chronic Cough

Speech Therapy in the Management of Chronic Cough Speech Therapy in the Management of Chronic Cough - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Speech Therapy in the Management of Chronic Cough (...) by (Responsible Party): Marta Dąbrowska, Medical University of Warsaw Study Details Study Description Go to Brief Summary: Speech and language intervention (speech therapy) is one of the few methods which seem to be useful in management of persistent chronic cough. This method has not been available for patients with cough in Poland so far.The aim of the study is to implement speech therapy to the management plan of patients with difficult-to-treat chronic cough and to analyze its efficacy in this particular

2018 Clinical Trials

192. A Study of the Effect of 20 mg Ambroxol Hydrochloride on Acute Cough.

A Study of the Effect of 20 mg Ambroxol Hydrochloride on Acute Cough. A Study of the Effect of 20 mg Ambroxol Hydrochloride on Acute Cough. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study (...) of the Effect of 20 mg Ambroxol Hydrochloride on Acute Cough. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03415269 Recruitment Status : Not yet recruiting First Posted : January 30, 2018 Last Update Posted : January 31, 2018

2018 Clinical Trials

193. Physiotherapy, and speech and language therapy intervention for patients with refractory chronic cough: a multicentre randomised control trial

Physiotherapy, and speech and language therapy intervention for patients with refractory chronic cough: a multicentre randomised control trial Physiotherapy, and speech and language therapy are emerging non-pharmacological treatments for refractory chronic cough. We aimed to investigate the efficacy of a physiotherapy, and speech and language therapy intervention (PSALTI) to improve health-related quality of life (HRQoL) and to reduce cough frequency in patients with refractory chronic cough.In (...) this multicentre randomised controlled trial, patients with refractory chronic cough were randomised to four weekly 1:1 sessions of either PSALTI consisting of education, laryngeal hygiene and hydration, cough suppression techniques, breathing exercises and psychoeducational counselling or control intervention consisting of healthy lifestyle advice. We assessed the change in HRQoL at week 4 with the Leicester Cough Questionnaire (LCQ). Secondary efficacy outcomes included 24-hour objective cough frequency

Full Text available with Trip Pro

2016 EvidenceUpdates

194. Are chronic cough and laryngopharyngeal reflux more common in obstructive sleep apnea patients? (PubMed)

Are chronic cough and laryngopharyngeal reflux more common in obstructive sleep apnea patients? To assess if there is a significant difference in the prevalence and severity of chronic cough symptoms in obstructive sleep apnea (OSA) patients versus non-OSA patients and examine this relationship in regard to laryngopharyngeal reflux (LPR) symptoms.Prospective cohort study.Patients referred to Northwestern Medicine Sleep Lab for home sleep testing were enrolled. Patients filled out the Leicester (...) Cough Questionnaire (LCQ) and Reflux Symptom Index (RSI) before completing sleep testing. Home sleep testing results were reviewed, and patients were separated into non-OSA and OSA groups by standard Apnea-Hypopnea Index (AHI) criteria. Demographic characteristics and questionnaire scores of the two groups were compared. The relationship between OSA severity, as determined by AHI, and LCQ and RSI scores was assessed.Of the 52 patients enrolled, 33 patients met criteria for OSA and 19 patients did

2018 Laryngoscope

195. Sevoflurane is an effective adjuvant to propofol-based total intravenous anesthesia for attenuating cough reflex in nonintubated video-assisted thoracoscopic surgery. (PubMed)

Sevoflurane is an effective adjuvant to propofol-based total intravenous anesthesia for attenuating cough reflex in nonintubated video-assisted thoracoscopic surgery. Nonintubated video-assisted thoracic surgery (VATS) has been widely developed during the recent years. Cough reflex is an inevitably encountered problem while approaching lung lesions, and it may induce major bleeding. Sevoflurane anesthesia may attenuate cough reflex by inhibiting the pulmonary irritant receptors. However (...) , the incidence of postoperative nausea and vomiting (PONV) in inhalational anesthesia is higher than in the propofol-based total intravenous anesthesia (TIVA). We investigated the effect of sevoflurane combination with propofol-based TIVA on cough reflex and PONV in nonintubated VATS.Ninety patients undergoing nonintubated VATS with laryngeal mask airway (LMA) and spontaneous breathing were randomly assigned for TIVA or propofol/sevoflurane anesthesia. In the TIVA group (n = 45), anesthesia was induced

Full Text available with Trip Pro

2018 Medicine

196. Cough in patients with lung cancer: a longitudinal observational study of characterisation and clinical associations. (PubMed)

Cough in patients with lung cancer: a longitudinal observational study of characterisation and clinical associations. Cough is common in patients with lung cancer, and current antitussive treatments are suboptimal. There are little published data describing cough in patients with lung cancer or work assessing clinical associations. The aim of this study is to fill that gap.This was a longitudinal prospective observational single-cohort study over 60 days. Patients were assessed through self (...) -reported validated scales and, in a subsample, ambulatory cough monitoring at study entry (day 0), day 30, and day 60.At study entry, 177 patients were included and 153 provided data at day 60. The median duration of cough was 52 weeks (interquartile range, 8.5-260). Cough was described as severe enough to warrant treatment in 62% of the patients. Depending on the scale used, performance status was associated with both cough severity and cough impact (P < .001) at study entry, whereas higher cough

Full Text available with Trip Pro

2018 Chest

197. Study to Evaluate the Safety and Tolerability of Mucinexâ„¢(Guaifenesin) 600 mg Extended-Release Bi-Layer Tablets in the Treatment of Otherwise Healthy Patients With Symptoms of Cough, Thickened Mucus and Chest Congestion

Study to Evaluate the Safety and Tolerability of Mucinexâ„¢(Guaifenesin) 600 mg Extended-Release Bi-Layer Tablets in the Treatment of Otherwise Healthy Patients With Symptoms of Cough, Thickened Mucus and Chest Congestion Study to Evaluate the Safety and Tolerability of Mucinex™(Guaifenesin) 600 mg Extended-Release Bi-Layer Tablets in the Treatment of Otherwise Healthy Patients With Symptoms of Cough, Thickened Mucus and Chest Congestion - Full Text View - ClinicalTrials.gov Hide glossary (...) Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study to Evaluate the Safety and Tolerability of Mucinex™(Guaifenesin) 600 mg Extended-Release Bi-Layer Tablets in the Treatment of Otherwise Healthy Patients With Symptoms of Cough, Thickened Mucus and Chest

2018 Clinical Trials

198. Predicting effective remifentanil concentration in 95% of patients to prevent emergence cough after laryngomicroscopic surgery. (PubMed)

Predicting effective remifentanil concentration in 95% of patients to prevent emergence cough after laryngomicroscopic surgery. Smooth emergence or cough prevention is a clinically important concern in patients undergoing laryngomicroscopic surgery (LMS). The purpose of this study was to estimate the effective concentration of remifentanil in 95% of patients (EC95) for the prevention of emergence cough after LMS under propofol anesthesia using the biased coin design (BCD) up-down method.A total (...) of 40 adult patients scheduled to undergo elective LMS were enrolled. Anesthesia induction and maintenance were performed with target-controlled infusion of propofol and remifentanil. Effective effect-site concentration (Ce) of remifentanil in 95% of patients for preventing emergence cough was estimated using a BCD method (starting from 1 ng/mL with a step size of 0.4 ng/mL). Hemodynamic and recovery profiles were observed after anesthesia.According to the study protocol, 20 patients were allocated

Full Text available with Trip Pro

2018 Medicine

199. Therapeutic Effects of Kangzhi Syrup in a Guinea Pig Model of Ovalbumin-Induced Cough Variant Asthma. (PubMed)

Therapeutic Effects of Kangzhi Syrup in a Guinea Pig Model of Ovalbumin-Induced Cough Variant Asthma. This study aimed to investigate the possible effects and underlying mechanisms of Kangzhi syrup on ovalbumin- (OVA-) induced cough variant asthma (CVA) in guinea pigs.All 48 guinea pigs were randomly assigned to four experimental groups: normal, OVA model with or without Kangzhi syrup (OVA and OVA + KZ), and OVA with Dexamethasone (OVA + DM). After sensitizing the guinea pigs, a cough challenge

Full Text available with Trip Pro

2018 Evidence-based Complementary and Alternative Medicine (eCAM)

200. Development of a prediction tool for patients presenting with acute cough in primary care: a prognostic study spanning six European countries. (PubMed)

Development of a prediction tool for patients presenting with acute cough in primary care: a prognostic study spanning six European countries. Accurate prediction of the course of an acute cough episode could curb antibiotic overprescribing, but is still a major challenge in primary care.The authors set out to develop a new prediction rule for poor outcome (re-consultation with new or worsened symptoms, or hospital admission) in adults presenting to primary care with acute cough.Data were (...) collected from 2604 adults presenting to primary care with acute cough or symptoms suggestive of lower respiratory tract infection (LRTI) within the Genomics to combat Resistance against Antibiotics in Community-acquired LRTI in Europe (GRACE; www.grace-lrti.org) Network of Excellence.Important signs and symptoms for the new prediction rule were found by combining random forest and logistic regression modelling. Performance to predict poor outcome in acute cough patients was compared

2018 British Journal of General Practice

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>