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181. Tools to help cut antibiotic prescribing for children with coughs and RTI

Tools to help cut antibiotic prescribing for children with coughs and RTI Tools to help cut antibiotic prescribing for children with coughs and RTI | Primary Care Respiratory Society ") The Primary Care Respiratory Society Inspiring best practice in respiratory care Search This website is for healthcare professionals only Tools to help cut antibiotic prescribing for children with coughs and RTI Tools to help cut antibiotic prescribing for children with coughs and RTI This article introduces

2017 Primary Care Respiratory Society

182. Acute cough

Acute cough Update 2013: revision of the 2011 version © 2013, Dutch College of General Practitioners www.nhg.org february 2013 Acute cough: cough lasting less than three weeks. ? Determine the degree of urgency during a (telephone) consultation: - Warning symptoms in young children: being severely ill (including fever, feeding problems, drowsiness, persistent crying, tachypnoea), severe dyspnoea, periods of apnoea (in young infants); - Warning symptoms in older children and adults: being (...) severely ill (fever, tachypnoea and/or confusion or drowsiness), severe dyspnoea, haemoptysis, pain linked to breathing; - Age 75 years. ? Ask about the cause: - nature of the cough, dyspnoea or wheezing, barking cough and whooping fits of coughing possibly followed by vomiting; - duration of the symptoms, recurrent cough symptoms (asthma, COPD); - additional symptoms (ENT, fever, general) consistent with asthma, COPD, an upper respiratory tract infection or influenza; - environmental factors: smoking

2013 Dutch College of General Practitioners (NHG)

183. A spoonful of honey helps a coughing child sleep

A spoonful of honey helps a coughing child sleep A spoonful of honey helps a coughing child sleep Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics A spoonful of honey helps a coughing child sleep View/ Open Date 2013-03 Format Metadata Abstract When a parent brings in a child (ages 1-5 years) with cough, runny nose

2013 PURLS

184. Somatic Cough Syndrome (previously referred to as psychogenic cough) and Tic Cough (previously referred to as habit cough) in Adults and Children: Chest Guideline and Expert Panel Report. Full Text available with Trip Pro

Somatic Cough Syndrome (previously referred to as psychogenic cough) and Tic Cough (previously referred to as habit cough) in Adults and Children: Chest Guideline and Expert Panel Report. We conducted a systematic review on the management of psychogenic cough, habit cough, and tic cough to update the recommendations and suggestions of the 2006 guideline on this topic.We followed the American College of Chest Physicians (CHEST) methodologic guidelines and the Grading of Recommendations (...) , Assessment, Development, and Evaluation framework. The Expert Cough Panel based their recommendations on data from the systematic review, patients' values and preferences, and the clinical context. Final grading was reached by consensus according to Delphi methodology.The results of the systematic review revealed only low-quality evidence to support how to define or diagnose psychogenic or habit cough with no validated diagnostic criteria. With respect to treatment, low-quality evidence allowed

2015 Chest

185. Cough - acute with chest signs in children

Cough - acute with chest signs in children Cough - acute with chest signs in children - NICE CKS Share Cough - acute with chest signs in children: Summary An upper respiratory tract infection should be considered in a child with a cough, symptoms and signs of infection, and a clear chest on examination. Common, potentially serious causes of cough in children include pneumonia, bronchiolitis, viral-induced wheeze, or an infective exacerbation of asthma. No combination of symptoms or signs has (...) made including the general assessment of a child with a cough, and the management of a child with community-acquired pneumonia. May 2011 — minor update. The 2010/2011 QIPP options for local implementation have been added to this topic. Issued in June 2011. February 2011 — topic structure revised to ensure consistency across CKS topics — no changes to clinical recommendations have been made. October 2010 — minor update. The recommendations regarding the management of children under the age of 5

2017 NICE Clinical Knowledge Summaries

186. To Cough or Not to Cough? Examining the Potential Utility of Cough Testing in the Clinical Evaluation of Swallowing Full Text available with Trip Pro

To Cough or Not to Cough? Examining the Potential Utility of Cough Testing in the Clinical Evaluation of Swallowing The clinical swallowing evaluation (CSE) represents a critical component of a comprehensive assessment of deglutition. Although universally utilized across clinical settings, the CSE demonstrates limitations in its ability to accurately identify all individuals with dysphagia. There exists a need to improve assessment and screening techniques to improve health outcomes, treatment (...) recommendations and ultimately mortality in individuals at risk for dysphagia. The following narrative review provides a summary of currently used validated CSE's and examines the potential role of cough testing and screening in the CSE.Recent evidence highlights a relationship between objective physiologic measurements of both voluntarily and reflexively induced cough and swallowing safety status across several patient populations. Although more research is needed across a wider range of patient populations

2016 Current physical medicine and rehabilitation reports

187. Human Cough as a Two-Stage Jet and Its Role in Particle Transport. Full Text available with Trip Pro

Human Cough as a Two-Stage Jet and Its Role in Particle Transport. The human cough is a significant vector in the transmission of respiratory diseases in indoor environments. The cough flow is characterized as a two-stage jet; specifically, the starting jet (when the cough starts and flow is released) and interrupted jet (after the source supply is terminated). During the starting-jet stage, the flow rate is a function of time; three temporal profiles of the exit velocity (pulsation, sinusoidal (...) and real-cough) were investigated in this study, and our results showed that the cough flow's maximum penetration distance was in the range of a 50.6-85.5 opening diameter (D) under our experimental conditions. The real-cough and sinusoidal cases exhibited greater penetration ability than the pulsation cases under the same characteristic Reynolds number (Rec) and normalized cough expired volume (Q/AD, with Q as the cough expired volume and A as the opening area). However, the effects of Rec and Q/AD

2017 PLoS ONE

188. The effects of respiratory muscle training on peak cough flow in patients with Parkinson's disease: a randomized controlled study. (Abstract)

The effects of respiratory muscle training on peak cough flow in patients with Parkinson's disease: a randomized controlled study. To compare the effects of an inspiratory versus and expiratory muscle-training program on voluntary and reflex peak cough flow in patients with Parkinson disease.A randomized controlled study.Home-based training program.In all, 40 participants with diagnosis of Parkinson's disease were initially recruited in the study and randomly allocated to three study groups (...) and a fixed resistance.Spirometric indices, maximum inspiratory pressure, maximum expiratory pressure, and peak cough flow during voluntary and reflex cough were assessed before and at two months after training.The magnitude of increase in maximum expiratory pressure ( d = 1.40) and voluntary peak cough flow ( d = 0.89) was greater for the expiratory muscle-training group in comparison to the control group. Reflex peak cough flow had a moderate effect ( d = 0.27) in the expiratory group in comparison

2018 Clinical rehabilitation Controlled trial quality: uncertain

189. Comparison of Lidocaine and Atropine on Fentanyl-Induced Cough: A Randomized Controlled Study. (Abstract)

Comparison of Lidocaine and Atropine on Fentanyl-Induced Cough: A Randomized Controlled Study. Fentanyl and atropine are drugs used for analgesia during induction and for premedication, respectively. The aim of this study was to observe the effect of atropine used for premedication on cough developing in association with fentanyl use during anesthesia induction.This was a single-blind, prospective, multi-arm, parallel, randomized clinical trial involving 120 patients between ages 3 and 15 years (...) undergoing general anesthesia. Patients were randomized into three groups: a control group (Group C), an atropine group (Group A), and a lidocaine group (Group L).Incidence of cough was 45% (n = 16) in Group C, 16% (n = 6) in Group A, and 16% in Group L (n = 6) (p = 0.009). Cough was moderate in two cases in Group A and in two in Group L, and mild in all others in these groups. In Group C, cough was mild in seven cases, moderate in six, and severe in two.We determined that premedication with atropine

2018 Journal of investigative surgery : the official journal of the Academy of Surgical Research Controlled trial quality: uncertain

190. Implementing Cough Reflex Testing in a Clinical Pathway for Acute Stroke: A Pragmatic Randomised Controlled Trial. (Abstract)

Implementing Cough Reflex Testing in a Clinical Pathway for Acute Stroke: A Pragmatic Randomised Controlled Trial. Silent aspiration is common after stroke and can lead to subsequent pneumonia. While standard bedside dysphagia assessments are ineffective at predicting silent aspiration, cough reflex testing (CRT) has shown promise for identifying patients at risk of silent aspiration. We investigated the impact of CRT on patient and service outcomes when embedded into a clinical pathway. 488

2018 Dysphagia Controlled trial quality: predicted high

191. [Clinical observation of post-infectious cough differentiated as wind-cold retention in the lung treated with scraping therapy and (Abstract)

[Clinical observation of post-infectious cough differentiated as wind-cold retention in the lung treated with scraping therapy and To compare the difference in the therapeutic effect on post-infectious cough differentiated as wind-cold retention in the lung between the combined therapy of scraping and xuanfei zhisou decoction and the simple application of xuanfei zhisou decoction.Eighty patients were randomized into a combined therapy group and a Chinese herbal medicine group, 40 cases in each (...) of foot-taiyang, the lung meridian of hand-taiyin, the conception vessel and the governor vessel, focusing on Tiantu (CV 22), Baihui (GV 20), Dazhui (GV 14), Feishu (BL 13), Fengmen (BL 12), Taiyuan (LU 9), Lieque (LU 7) and Fengchi (GB 20), once a week and one-week treatment as one session. Totally, the continuous two sessions were required in the two groups. The cough symptom score, cough remission time, relapse, TCM syndrome score, the score of Leicester cough questionnaire (LCQ), SP concentration

2018 Zhongguo zhen jiu = Chinese acupuncture & moxibustion Controlled trial quality: uncertain

192. [Micro-invasive embedding combined with montelukast sodium for children cough variant asthma:a randomized controlled trial]. (Abstract)

[Micro-invasive embedding combined with montelukast sodium for children cough variant asthma:a randomized controlled trial]. To observe the effects of micro-invasive embedding combined with montelukast sodium and simple montelukast sodium for children cough variant asthma (CVA).A total of 240 patients were randomly assigned into an observation group and a control group, 120 cases in each one. Considering of cases dropping, 101 patients in the observation group and 105 cases in the control group (...) were included. Montelukast sodium chewable tablets were applied before sleep for 3 months in the control group, 5 mg a time, once a day. Based on the treatment as the control group, micro-invasive embedding was used for 3 months in the observation group, twice in the first month and once in the other two months. The acupoints were Feishu (BL 13), Danzhong (CV 17), Dingchuan (EX-B 1), and Zusanli (ST 36). Follow-up was conducted 9 months after treatment in the two groups. The cough score, serum

2018 Zhongguo zhen jiu = Chinese acupuncture & moxibustion Controlled trial quality: uncertain

193. Efficacy Of Intravenous Lignocain Vs Sevoflurane In Prevention Of Coughing And Desaturation At Extubation In Children. (Abstract)

Efficacy Of Intravenous Lignocain Vs Sevoflurane In Prevention Of Coughing And Desaturation At Extubation In Children. Inadvertent coughing and desaturation are the most commonly faced and feared respiratory complications in post-anaesthesia period. The study was done to compare the efficacy of intravenous lignocaine versus sevoflurane in prevention of coughing and desaturation at extubation in children less than 6 years of age.This Randomized Control Trial was carried out from May 2013 to May (...) , breathing circuit changed and sevoflurane started at minimum alveolar concentration (MAC 3-4%) for 3 minutes prior to extubation. Assessment for extubation was clinical. Oxygen saturation and severity of coughing were noted for 5 consecutive minutes, after extubation.In group-A, 156 patients were less than 2 years of age while in group-B, 135 patients were less than 2 years old. In group-A, 199 and in group-B, 220 children were 2-6 years of age respectively. Post stratification the p-value for weight

2018 Journal of Ayub Medical College, Abbottabad : JAMC Controlled trial quality: uncertain

194. Efficacy and tolerability of a complex homeopathic drug in children suffering from dry cough-A double-blind, placebo-controlled, clinical trial. (Abstract)

Efficacy and tolerability of a complex homeopathic drug in children suffering from dry cough-A double-blind, placebo-controlled, clinical trial. A randomised, placebo-controlled clinical trial in children suffering from acute dry cough was performed to assess the efficacy and tolerability of a complex homeopathic drug (Drosera, Coccus cacti, Cuprum Sulfuricum, Ipecacuanha=Monapax syrup, short: verum).89 children received verum and 91 received placebo daily for 7 days (age groups 0.5-3, 4-7 (...) and 8-12 years). The primary efficacy variable was the improvement of the Cough Assessment Score. Tolerability and compliance were also assessed. A confirmatory statistical analysis was performed for the primary efficacy variable and a descriptive analysis for the secondary parameters.The Cough Assessment Score showed an improvement of 5.2±2.6 points for children treated with verum and 3.2±2.6 points in the placebo group (p<0.0001). The difference of the least square means of the improvements

2018 Drug research Controlled trial quality: predicted high

195. The analgesic efficacy of forced coughing during cervical punch biopsy: A prospective randomised controlled study. (Abstract)

The analgesic efficacy of forced coughing during cervical punch biopsy: A prospective randomised controlled study. Cervical punch biopsies are a common ambulatory procedure, performed routinely by gynaecologists. The aim of the present study was to assess the efficacy of forced coughing as a pain-reducing technique during cervical punch biopsy compared to a control group.The study was a prospective randomised-control trial. The study group comprised 90 women who underwent cervical punch (...) biopsies during investigation of abnormal Pap test results. The women were randomly assigned to 'cough' and control groups. Pain was measured on a 10 cm visual analogue scale (VAS) during different stages of the procedure.VAS pain score during biopsies was significantly lower in the 'cough' group. The median pain level in the 'cough' group was 1.5, compared to 4.0 in the control group. Eighty percent of the women in the 'cough' group reported a pain level of 2.0 or less compared to 40% of the women

2018 The Australian & New Zealand journal of obstetrics & gynaecology Controlled trial quality: uncertain

196. A novel formulation of inhaled sodium cromoglicate (PA101) in idiopathic pulmonary fibrosis and chronic cough: a randomised, double-blind, proof-of-concept, phase 2 trial. Full Text available with Trip Pro

A novel formulation of inhaled sodium cromoglicate (PA101) in idiopathic pulmonary fibrosis and chronic cough: a randomised, double-blind, proof-of-concept, phase 2 trial. Cough can be a debilitating symptom of idiopathic pulmonary fibrosis (IPF) and is difficult to treat. PA101 is a novel formulation of sodium cromoglicate delivered via a high-efficiency eFlow nebuliser that achieves significantly higher drug deposition in the lung compared with the existing formulations. We aimed to test (...) the efficacy and safety of inhaled PA101 in patients with IPF and chronic cough and, to explore the antitussive mechanism of PA101, patients with chronic idiopathic cough (CIC) were also studied.This pilot, proof-of-concept study consisted of a randomised, double-blind, placebo-controlled trial in patients with IPF and chronic cough and a parallel study of similar design in patients with CIC. Participants with IPF and chronic cough recruited from seven centres in the UK and the Netherlands were randomly

2018 The lancet. Respiratory medicine Controlled trial quality: predicted high

197. Standing Vs Supine; Does it Matter in Cough Stress Testing? (Abstract)

Standing Vs Supine; Does it Matter in Cough Stress Testing? The aim of this study was to compare the sensitivity of cough stress test in the standing versus supine position in the evaluation of incontinent females.We performed a prospective observational study of women with the chief complaint of urinary incontinence (UI) undergoing a provocative cough stress test (CST). Subjects underwent both a standing and a supine CST. Testing order was randomized via block randomization. Cough stress test (...) was performed in a standard method via backfill of 200 mL or until the subject described strong urge. The subjects were asked to cough, and the physician documented urine leakage by direct observation. The gold standard for stress UI diagnosis was a positive CST in either position.Sixty subjects were enrolled, 38 (63%) tested positive on any CST, with 38 (63%) positive on standing compared with 29 (28%) positive on supine testing. Nine women (15%) had positive standing and negative supine testing

2018 Female pelvic medicine & reconstructive surgery Controlled trial quality: uncertain

198. Evaluation of the quality and value of data sources for postmarket surveillance of the safety of cough and cold medications in children. Full Text available with Trip Pro

Evaluation of the quality and value of data sources for postmarket surveillance of the safety of cough and cold medications in children. The purpose of this report is to evaluate the quality of data sources used to study cough and cold medication (CCM) safety in children via the Pediatric Cough and Cold Safety Surveillance System.The System utilized the National Poison Data System (NPDS), FDA Adverse Event Reporting System (FAERS), English-language medical literature, manufacturer postmarket

2018 BMC Medical Research Methodology

199. Impact of antibiotics for children presenting to general practice with cough on adverse outcomes: secondary analysis from a multicentre prospective cohort study. Full Text available with Trip Pro

Impact of antibiotics for children presenting to general practice with cough on adverse outcomes: secondary analysis from a multicentre prospective cohort study. Clinicians commonly prescribe antibiotics to prevent major adverse outcomes in children presenting in primary care with cough and respiratory symptoms, despite limited meaningful evidence of impact on these outcomes.To estimate the effect of children's antibiotic prescribing on adverse outcomes within 30 days of initial (...) consultation.Secondary analysis of 8320 children in a multicentre prospective cohort study, aged 3 months to <16 years, presenting in primary care across England with acute cough and other respiratory symptoms.Baseline clinical characteristics and antibiotic prescribing data were collected, and generalised linear models were used to estimate the effect of antibiotic prescribing on adverse outcomes within 30 days (subsequent hospitalisations and reconsultation for deterioration), controlling for clustering

2018 British Journal of General Practice

200. The pathogenetic mechanisms of cough in idiopathic pulmonary fibrosis. Full Text available with Trip Pro

The pathogenetic mechanisms of cough in idiopathic pulmonary fibrosis. Idiopathic pulmonary fibrosis is a peripheral subpleural interstitial lung disorder limited to the lung not involving the airways. It has a poor prognosis (survival less than 5 years) and commonly an interstitial pneumonia radiological pattern. Patients complain of a chronic dry cough in 80% of cases. A cough is often the first symptom of this rare disease, preceding dyspnea by years, and is associated with a poor prognosis (...) , high dyspnea scores and low FVC percentages. The pathogenetic mechanisms leading to coughing in IPF are unclear. This review focuses on recent evidence of cough pathophysiology in this disease. Gastroesophageal reflux may promote coughing in IPF patients; bile salts and pepsin may be abundant in BAL of these patients, inducing overproduction of TGF-β by airway epithelial cells and mesenchymal transition with fibroblast recruitment/activation and extracellular matrix deposition. Patients have

2018 Internal and emergency medicine

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