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1. Cough (acute): antimicrobial prescribing

Cough (acute): antimicrobial prescribing Cough (acute Cough (acute): antimicrobial prescribing ): antimicrobial prescribing NICE guideline Published: 7 February 2019 nice.org.uk/guidance/ng120 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When (...) with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Cough (acute): antimicrobial prescribing (NG120) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 36Contents Contents Overview 4 Who is it for? 4 Recommendations 5

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

2. Somatic Cough Syndrome (Previously Referred to as Psychogenic Cough) and Tic Cough (Previously Referred to as Habit Cough) in Adults and Children

Somatic Cough Syndrome (Previously Referred to as Psychogenic Cough) and Tic Cough (Previously Referred to as Habit Cough) in Adults and Children 24 Evidence-Based Medicine [ 148#1 CHEST JULY 2015 ] S o ma tic C o ug h S y ndr o me (P r e vio u sl y Ref er r ed t o as Psychogenic Cough) and Tic Cough (Previously Referred to as Habit Cough) in Adults and Children CHEST Guideline and Expert Panel Report Anne E. Vertigan , PhD, MBA, BAppSc(SpPath) ; Mohammad H. Murad , MD, MPH ; Tamara Pringsheim (...) , MD ; Anthony Feinstein , PhD, MD ; Anne B. Chang , MBBS, PhD, MPH ; Peter A. Newcombe , PhD ; Bruce K. Rubin , MD, MEngr, MBA ; Lorcan P. McGarvey , MD ; Kelly Weir , MSpPath ; Kenneth W. Altman , MD, PhD ; Miles Weinberger , MD ; and Richard S. Irwin , MD, Master FCCP ; on behalf of the CHEST Expert Cough Panel BACKGROUND: We conducted a systematic review on the management of psychogenic cough, habit cough, and tic cough to update the recommendations and suggestions of the 2006 guideline

2015 American College of Chest Physicians

3. Speech and language therapy for management of chronic cough. (PubMed)

Speech and language therapy for management of chronic cough. Cough both protects and clears the airway. Cough has three phases: breathing in (inspiration), closure of the glottis, and a forced expiratory effort. Chronic cough has a negative, far-reaching impact on quality of life. Few effective medical treatments for individuals with unexplained (idiopathic/refractory) chronic cough (UCC) are known. For this group, current guidelines advocate the use of gabapentin. Speech and language therapy (...) of the two studies included children. The duration of treatment and length of sessions varied between studies from four sessions delivered weekly, to four sessions over two months. Similarly, length of sessions varied slightly from one 60-minute session and three 45-minute sessions to four 30-minute sessions. The control interventions were healthy lifestyle advice in both studies.One study contributed HRQoL data, using the Leicester Cough Questionnaire (LCQ), and we judged the quality of the evidence

2019 Cochrane

4. Whooping cough infection common in school aged children with stubborn coughs

Whooping cough infection common in school aged children with stubborn coughs Whooping cough infection common in school aged children with stubborn coughs Discover Portal Discover Portal Whooping cough infection common in school aged children with stubborn coughs Published on 26 June 2014 doi: This NIHR-funded study found that almost a fifth of children aged five to 15 years who visited their GP with persistent cough showed signs of recent whooping cough infection, despite having a booster (...) vaccination before school age. These data, from 22 GP practices in Thames Valley UK, describe the duration of vaccine-induced immunity and the burden of disease in adolescents. This may inform policy discussion about the potential need for a national adolescent whooping cough booster programme in the UK. Share your views on the research. Why was this study needed? Whooping cough (pertussis) is one of the most common vaccine preventable diseases causing almost 300,000 childhood deaths a year worldwide

2018 NIHR Dissemination Centre

5. Whooping cough infection common in school aged children with stubborn coughs

Whooping cough infection common in school aged children with stubborn coughs Whooping cough infection common in school aged children with stubborn coughs Discover Portal Discover Portal Whooping cough infection common in school aged children with stubborn coughs Published on 26 June 2014 doi: This NIHR-funded study found that almost a fifth of children aged five to 15 years who visited their GP with persistent cough showed signs of recent whooping cough infection, despite having a booster (...) vaccination before school age. These data, from 22 GP practices in Thames Valley UK, describe the duration of vaccine-induced immunity and the burden of disease in adolescents. This may inform policy discussion about the potential need for a national adolescent whooping cough booster programme in the UK. Share your views on the research. Why was this study needed? Whooping cough (pertussis) is one of the most common vaccine preventable diseases causing almost 300,000 childhood deaths a year worldwide

2018 NIHR Dissemination Centre

6. Are Antibiotics Effective in the Treatment of Children With Prolonged Wet Cough?

Are Antibiotics Effective in the Treatment of Children With Prolonged Wet Cough? Are Antibiotics Effective in the Treatment of Children With Prolonged Wet Cough? - Annals of Emergency Medicine Email/Username: Password: Remember me Search Terms Search within Search Share this page Access provided by Volume 73, Issue 5, Pages 453–455 Are Antibiotics Effective in the Treatment of Children With Prolonged Wet Cough? x Brit Long , MD (EBEM Commentator) , x Michael D. April , MD, DPhil (EBEM (...) Commentator) Department of Emergency Medicine, San Antonio Uniformed Services Health Education Consortium, Fort Sam Houston, TX DOI: | Publication History Published online: November 13, 2018 Expand all Collapse all Article Outline Take-Home Message Antibiotics may improve clinical cure and reduce progression of illness in children with prolonged wet cough. Methods Data Sources Authors identified trials from the Cochrane Airways Trials Register, CENTRAL, MEDLINE OvidSP, and EMBASE OvidSP through September

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2019 Annals of Emergency Medicine Systematic Review Snapshots

7. Whooping cough (pertussis): immunisation of healthcare workers

Whooping cough (pertussis): immunisation of healthcare workers Whooping cough (pertussis): immunisation of healthcare workers - GOV.UK GOV.UK uses cookies to make the site simpler. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance Whooping cough (pertussis): immunisation of healthcare workers Information on the immunisation of health professionals and advice for healthcare workers exposed to whooping cough. Published 11 February 2013 Last updated 22 July 2019 (...) — From: Contents Whooping cough immunisation of health professionals Immunisation of health professionals was considered by the Joint Committee on Vaccination and Immunisation ( that healthcare workers with direct contact with vulnerable patients (pregnant women or infants) are priority groups for immunisation. However, due to a global shortage of pertussis vaccine, it has not been possible to implement the was published providing information on the recommended groups for vaccination and vaccine

2019 Public Health England

8. Honey for acute cough in children. (PubMed)

Honey for acute cough in children. Cough causes concern for parents and is a major cause of outpatient visits. Cough can impact quality of life, cause anxiety, and affect sleep in children and their parents. Honey has been used to alleviate cough symptoms. This is an update of reviews previously published in 2014, 2012, and 2010.To evaluate the effectiveness of honey for acute cough in children in ambulatory settings.We searched CENTRAL (2018, Issue 2), which includes the Cochrane Acute (...) for this update due to lack of institutional access.Randomised controlled trials comparing honey alone, or in combination with antibiotics, versus no treatment, placebo, honey-based cough syrup, or other over-the-counter cough medications for children aged 12 months to 18 years for acute cough in ambulatory settings.We used standard methodological procedures expected by Cochrane.We included six randomised controlled trials involving 899 children; we added three studies (331 children) in this update.We

2018 Cochrane

12. Antibiotics for prolonged wet cough in children. (PubMed)

Antibiotics for prolonged wet cough in children. Cough is a frequent symptom presenting to doctors. The most common cause of childhood chronic (greater than fours weeks' duration) wet cough is protracted bacterial bronchitis (PBB) in some settings, although other more serious causes can also present this way. Timely and effective management of chronic wet or productive cough improves quality of life and clinical outcomes. Current international guidelines suggest a course of antibiotics (...) is the first treatment of choice in the absence of signs or symptoms specific to an alternative diagnosis. This review sought to clarify the current evidence to support this recommendation.To determine the efficacy of antibiotics in treating children with prolonged wet cough (excluding children with bronchiectasis or other known underlying respiratory illness) and to assess risk of harm due to adverse events.We undertook an updated search (from 2008 onwards) using the Cochrane Airways Group Specialised

2018 Cochrane

13. Assessment of chronic cough

Assessment of chronic cough Assessment of chronic cough - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of chronic cough Last reviewed: February 2019 Last updated: June 2018 Summary Cough is the most common presenting symptom in primary practice. Schappert SM, Burt CW. Ambulatory care visits to physician offices, hospital outpatient departments, and emergency departments: United States, 2001-02. Vital (...) Health Stat 13. 2006 Feb;(159):1-66. http://www.cdc.gov/nchs/data/series/sr_13/sr13_159.pdf http://www.ncbi.nlm.nih.gov/pubmed/16471269?tool=bestpractice.com Sub-acute cough is defined as cough persisting for 3 to 8 weeks, and chronic cough as that persisting for more than 8 weeks. Irwin RS, French CL, Chang AB, et al. Classification of cough as a symptom in adults and management algorithms: CHEST guideline and expert panel report. Chest. 2018 Jan;153(1):196-209. http://journal.chestnet.org/article

2018 BMJ Best Practice

14. Upper airway cough syndrome

Upper airway cough syndrome Upper airway cough syndrome - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Upper airway cough syndrome Last reviewed: February 2019 Last updated: September 2018 Summary Chronic cough that occurs with coexisting upper airway symptoms, including abnormal sensations arising from the throat and a postnasal drip sensation. Sensations attributed to nasal disease may actually be manifestations (...) of a sensory neuropathic process and not relate to rate or quantity of nasal discharge. Most common cause of chronic cough in adults. No pathognomonic findings exist; diagnosis should be determined by considering a combination of criteria, including the history, physical exam, imaging, and, ultimately, the response to therapy. Trial of empirical therapy with a first-generation antihistamine plus a decongestant is both diagnostic and therapeutic. Non-pharmacological therapies also form part of the treatment

2018 BMJ Best Practice

15. Upper airway cough syndrome

Upper airway cough syndrome Upper airway cough syndrome - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Upper airway cough syndrome Last reviewed: February 2019 Last updated: September 2018 Summary Chronic cough that occurs with coexisting upper airway symptoms, including abnormal sensations arising from the throat and a postnasal drip sensation. Sensations attributed to nasal disease may actually be manifestations (...) of a sensory neuropathic process and not relate to rate or quantity of nasal discharge. Most common cause of chronic cough in adults. No pathognomonic findings exist; diagnosis should be determined by considering a combination of criteria, including the history, physical exam, imaging, and, ultimately, the response to therapy. Trial of empirical therapy with a first-generation antihistamine plus a decongestant is both diagnostic and therapeutic. Non-pharmacological therapies also form part of the treatment

2018 BMJ Best Practice

16. Symptomatic treatment of the cough in whooping cough. (PubMed)

Symptomatic treatment of the cough in whooping cough. Around 16 million cases of whooping cough (pertussis) occur worldwide each year, mostly in low-income countries. Much of the morbidity of whooping cough in children and adults is due to the effects of the paroxysmal cough. Cough treatments proposed include corticosteroids, beta2-adrenergic agonists, pertussis-specific immunoglobulin, antihistamines and possibly leukotriene receptor antagonists (LTRAs).To assess the effectiveness and safety (...) of interventions to reduce the severity of paroxysmal cough in whooping cough in children and adults.We updated our searches of the Cochrane Central Register of Controlled Trials (CENTRAL, 2014, Issue 1), which contains the Cochrane Acute Respiratory Infections Group's Specialised Register, the Database of Abstracts of Reviews of Effects (DARE 2014, Issue 2), accessed from The Cochrane Library, MEDLINE (1950 to 30 January 2014), EMBASE (1980 to 30 January 2014), AMED (1985 to 30 January 2014), CINAHL (1980

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2014 Cochrane

17. Is there evidence backing the use of guaifensin for cough secondary to upper respiratory infection (URI)?

Is there evidence backing the use of guaifensin for cough secondary to upper respiratory infection (URI)? Chiefs’ Inquiry Corner – 8/12/19 – Clinical Correlations Search Chiefs’ Inquiry Corner – 8/12/19 August 12, 2019 2 min read Clinicians frequently recommend symptomatic management for cough, specifically over-the-counter (OTC) medications, but the data doesn’t necessarily back it up. A 2014 Cochrane review of OTC medications for acute cough in adults and children found that among the 29 (...) randomized, placebo-controlled studies, there was poor reporting and little quantitative data. Among the three studies that specifically compared guaifensin and placebo, only one showed a significant difference, with patients taking guaifensin reporting a greater reduction in cough frequency and intensity after 3 days. Overall, only 11 of the 29 studies showed positive results for OTC medications such as guaifensin, dextromethorphan, and pseudophedrine. “Symptomatic management” may be an even more

2019 Clinical Correlations

18. Cough augmentation techniques for extubation or weaning critically ill patients from mechanical ventilation. (PubMed)

Cough augmentation techniques for extubation or weaning critically ill patients from mechanical ventilation. There are various reasons why weaning and extubation failure occur, but ineffective cough and secretion retention can play a significant role. Cough augmentation techniques, such as lung volume recruitment or manually- and mechanically-assisted cough, are used to prevent and manage respiratory complications associated with chronic conditions, particularly neuromuscular disease, and may (...) improve short- and long-term outcomes for people with acute respiratory failure. However, the role of cough augmentation to facilitate extubation and prevent post-extubation respiratory failure is unclear.Our primary objective was to determine extubation success using cough augmentation techniques compared to no cough augmentation for critically-ill adults and children with acute respiratory failure admitted to a high-intensity care setting capable of managing mechanically-ventilated people

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2017 Cochrane

19. Menthol Cough Drops and Cough Severity.

Menthol Cough Drops and Cough Severity. Menthol Cough Drops and Cough Severity. – Less Is More Search for: Simpler & Better Medicine Menu / Summary: For adolescent and adult patients with cough, using non-mentholated cough drops may be associated with having a less severe cough compared to using mentholated cough drops. Strength of Recommendation = B Advertisements Like this: Like Loading... Categories: Tags: Post navigation Simpler, Better Medicine Indexing evidence for "less medical

2018 Less Is More Blog

20. Impaired cough suppression in chronic refractory cough. (PubMed)

Impaired cough suppression in chronic refractory cough. Functional brain imaging in individuals with chronic cough demonstrates reduced activation in cortical regions associated with voluntary cough suppression. Little is known about the ability of patients with chronic cough to suppress cough. This study aimed to compare the ability to voluntarily suppress cough during inhaled capsaicin challenge in participants with chronic refractory cough with that in healthy controls. This study also aimed (...) to assess the repeatability of capsaicin challenge test with voluntary cough suppression.Participants with chronic refractory cough and healthy controls underwent inhaled capsaicin challenge tests whilst attempting to suppress their cough responses. After 5 days either a conventional capsaicin challenge test with no cough suppression attempt, or a repeat test with an attempt at cough suppression was performed. Threshold capsaicin concentrations required to elicit 1, 2 and 5 coughs were calculated

2019 European Respiratory Journal

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