How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

741 results for

Corneal Reflex

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

161. Repeatability and Reproducibility of the IOLMaster 700 Vers 1.70 and Agreement With IOLMaster 700 Vers. 1.50 and Pentacam

ocular infection or inflammation. Poor tear film/insufficient corneal reflex. Best corrected visual acuity worse than 20/200 in the study eye. Physical inability to be positioned at the slit-lamp biomicroscope or study devices (e.g. torticollis, head tremor, etc.). Insufficient eyelid opening or eyelashes which partially conceal alignment or keratometry reflections and prevent capture of all measurements. Inability to fixate (e.g. due to nystagmus, amblyopia or ocular disease, such as macular (...) and reproducibility of the IOLMaster 700 SW Vers 1.70. The following parameters will be evaluated for Total Keratometry, (TK) and Posterior Corneal Surface (PCS): cylinder (CYL), Axis (A) spherical equivalent (SE) Specific Objectives: To compare the agreement of SE between IOLMaster 700 SW Vers. 1.70 and IOLMaster 700 SW Vers. 1.50 (Carl Zeiss Meditec AG, Jena, Germany) To compare the agreement of Cylinder magnitude and axis between IOLMaster 700 SW Version 1.70 and Pentacam To evaluate the repeatability

2018 Clinical Trials

162. Astigmatism in Keratoconus Patients

Study Description Go to Brief Summary: Keratoconus is a bilateral (but usually asymmetrical) non-inflammatory progressive thinning process of the cornea. It manifests as characteristic cone-like ectasia of the cornea associated with irregular stromal thinning, resulting in a cone-like bulge , which causing irregular astigmatism and vision impairment. Condition or disease Intervention/treatment Phase Keratoconus Device: Pentacam Not Applicable Detailed Description: Keratoconus is the most common form (...) of corneal ectasia, with an incidence of 50-230 per 100,000 persons.Pentacam used diagnose & detect the progression in patients with keratoconus and also provide a detailed information about corneal tomography and topography. In the last few years, it has been shown that in healthy individuals the posterior corneal surface has not only a different amount of astigmatism but also a different alignment of the steep meridian. The aim of this research is to compare the amount and axis alignment of anterior

2018 Clinical Trials

163. Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination

-Pupillary light reflex with bright light. 3-Corneal reflexes with the use of cotton swab or tissue paper. 4-Gag reflex with a tongue depressor looking for bilateral palatal elevation. 5-Cough with tracheal suctioning at the carinal level) and GCS re-evaluated Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more

2018 Clinical Trials

164. Reading Analysis in Ophthalmologic Patients

that reading ability is reduced in patients with various ocular diseases. Especially, pathologies effecting the posterior pole (central and paracentral vision) might impair reading parameters significantly. Recently, the Eyetracker Eyelink 1000 (SR Research Ltd, Canada) became available. It´s application was described previously. Briefly, a high-speed infrared camera detects the position of eye (pupil and corneal reflex) and in turn the direction of gaze 500 times per second. During the calibration process (...) Absence of ocular disease (Group 1) Present ocular disease (age-related macular degeneration, glaucoma, diabetic maculopathy, epiretinal membrane/macular hole) as judged by the investigator (Group 2 - 5) Maximum of allowed cylinder-power in the spectacles: +1.50D Exclusion Criteria: Ocular pathologies, that may interfere with study measurements, such as corneal scars In case of pregnancy (pregnancy test will be taken prior to inclusion into the study in women of reproductive age) Contacts

2018 Clinical Trials

165. Recommendations for the Management of Cerebral and Cerebellar Infarction with Swelling

infarction, a decrease in level of consciousness occurs as a result of brainstem compression and therefore may include early loss of corneal reflexes and the development of miosis. Standardized definitions should be established to facilitate multicenter and population-based studies of incidence, prevalence, risk factors, and outcomes. Identification of patients at high risk for brain swelling should include clinical and neuroimaging data. If a full resuscitative status is warranted in a patient (...) physiological parameters, but early extubation in patients with a decompressive craniectomy for cerebellar infarcts can be problematic because of abnormal oropharyngeal function, lack of strong cough, and copious thick secretions. 90 The presence of a cough and gag reflex and normal eye movements may predict successful extubation. 91 Airway and Mechanical Ventilation: Recommendations 1. Maintaining normocarbia is reasonable (Class IIa; Level of Evidence C). 2. Intubation may be considered for patients

2014 Congress of Neurological Surgeons

167. Routine newborn assessment

. Newborn examination continued Aspect Clinical assessment Indications for further investigation ? Urgent follow-up Face • Symmetry of structure, features and movement • Asymmetry on crying • Eyes o Size and structure o Position in relation to the nasal bridge o Red eye reflex • Hazy, dull cornea • Absent red reflex • Pupils unequal, dilated or constricted • Purulent conjunctivitis • Nose o Position and symmetry of the nares and septum • Nasal flaring ? Non-patent nares especially if bilateral (...) • Spinal column, skin • Symmetry of scapulae, buttocks • Behaviour, posture • Muscle tone, spontaneous movements • Cry • Reflexes - Moro, Suck, Grasp Queensland Clinical Guideline: Routine newborn assessment. Guideline No: MN14.04-V4-R19 Shoulders, arms, hands • Length, proportions, symmetry • Structure, number of digits Discuss Document Refer • Discuss findings with parents • Document in health record(s) • Refer as indicated • Size, shape, symmetry • Palpate liver, spleen, kidneys • Umbilicus • Male

2014 Queensland Health

168. Routine newborn assessment

. Newborn examination continued Aspect Clinical assessment Indications for further investigation ? Urgent follow-up Face • Symmetry of structure, features and movement • Asymmetry on crying • Eyes o Size and structure o Position in relation to the nasal bridge o Red eye reflex • Hazy, dull cornea • Absent red reflex • Pupils unequal, dilated or constricted • Purulent conjunctivitis • Nose o Position and symmetry of the nares and septum • Nasal flaring ? Non-patent nares especially if bilateral (...) • Spinal column, skin • Symmetry of scapulae, buttocks • Behaviour, posture • Muscle tone, spontaneous movements • Cry • Reflexes - Moro, Suck, Grasp Queensland Clinical Guideline: Routine newborn assessment. Guideline No: MN14.04-V4-R19 Shoulders, arms, hands • Length, proportions, symmetry • Structure, number of digits Discuss Document Refer • Discuss findings with parents • Document in health record(s) • Refer as indicated • Size, shape, symmetry • Palpate liver, spleen, kidneys • Umbilicus • Male

2014 Clinical Practice Guidelines Portal

169. The ANZICS statement on death and organ donation

and mechanical ventilation during which the preconditions for clinical determination of brain death are fulfilled and the patient is unresponsive (Glasgow Coma Score 3), has no pupil reaction to light, no cough reflex and no spontaneous breathing efforts, before clinical testing to determine brain death. Previously, a minimum of four hours was recommended, with a minimum of two hours before clinical testing was repeated. However, there has been no reported instance of clinical testing determining brain death (...) system activity in order to define criteria for abandoning ongoing intensive therapy. They referred to an isoelectric electro-encephalogram and absent evoked cerebral responses, reporting that the heart rate did not change after giving atropine while it increased after dextroamphetamine. Later in the same year, Mollaret and Goulon in Paris 14 described 23 patients with the same syndrome (deep coma with no spontaneous respiration, no reflexes, polyuria and low blood pressure if noradrenaline

2013 Clinical Practice Guidelines Portal

172. EFNS?ENS Guidelines on the diagnosis and management of disorders associated with dementia

limbs, usually of the limb‐kinetic type. During the evolution of the disease, postural and action tremor, limb dystonia, focal reflex myoclonus, postural instability and falls, alien hand‐like phenomenon, corticospinal signs, oculomotor and eyelid motor deficits and dysarthria develop in more than half of cases. CBD, the commonest cause of CBS, is a 4‐repeat tauopathy defined by unique neuropathological features including cortical atrophy, nigral degeneration, achromasia (swollen neurons (...) hallucinations . Genetic prion diseases Genetic prion diseases occurring in 10–15% of cases are caused by prion protein gene ( PRNP ) mutations, showing the patterns of autosomal‐dominant inheritance with incomplete penetrance. The disorders manifest as familial Creutzfeldt–Jakob disease (fCJD), Gerstmann–Sträussler–Scheinker disease (GSS) or fatal familial insomnia (FFI). Accidentally transmitted (iatrogenic) CJD has been related to corneal graft transplantation, contaminated human pituitary‐derived growth

2012 European Academy of Neurology

173. Is Anesthetic Loss of Consciousness a Top Down or Bottom up Phenomenon. What Does the Neurologic Examination Say?.

ke0 1,21 min-1 using a calculated target of 5.4 ug/ml (loss of counsciousness EC95) and slow induction (GL) 10 mg/kg/h with calculated effect site concentrations (CeCALC) same PK model. The same neurologist, blind to the correspondent group, evaluated all the patients every 30 sec using the coma FOUR scale until loss of counsciousness (LOC), defined as a FOUR (E0 no eyes opening response and /or M0 no motor response). At LOC the existance of brainstem reflex was evaluated (B no pupil and corneal (...) reflex), respiratory pattern (R apnoea), CeCALC and patient state index (PSI) SEDline™ was recorded during all the examination. After LOC in both groups we maintain in GR the initial target (5.3 ug/ml) and the LOC CeCALC during 10 min without intervention, except respiratory support if it was required. Frontal EEG 4 channel and spectrogram from SEDline monitor was extracted for each case and posterior analysis. Fisher exact test was used to describe primary outcome and difference between B and R

2017 Clinical Trials

174. A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopic Patients With Treatments to Optimize the Ocular Surface Before Implantation

, recurrent corneal erosion or severe basement membrane disease, and pterygium extending onto the cornea. 1.2.13 Patients with ophthalmoscopic/topographic signs of keratoconus or those who are keratoconus suspect. 1.2.14 Patients with history of Herpes zoster or Herpes simplex keratitis. 1.2.15 Patients with any progressive retinal disease or subjects with a history or evidence of retinal vascular occlusion and/or hypercoagulability, because of the risks associated with high pressures during suction (...) application. 1.2.16 Patients with known history of steroid-responsive intraocular pressure increases, glaucoma, preoperative IOP > 21 mm Hg, or are otherwise suspected of having glaucoma. 1.2.17 Patients with amblyopia or strabismus or those who are at risk for developing strabismus postoperatively as determined by corneal light reflex and cover-uncover testing. 1.2.18 Patients with diabetic retinopathy, collagen, vascular, diagnosed autoimmune disease (e.g., lupus, rheumatoid arthritis, fibromylagia

2017 Clinical Trials

175. Walnut Shell Glasses Moxibustion for Dry Eye Syndrome

three times to take the mean. change from baseline in SchimerⅠtext [ Time Frame: week 2, week 4 ] Evaluation the tear secretion, do not use ocular surface anesthetic, measuring the amount of reflex tear secretion. Place the test paper in the middle and outer 1/3 of the conjunctiva of the lower eyelid, and instruct the patient to lighten his eyes or look down at the bottom, and remove it after 5 minutes to measure the wetness from the beginning of the bend. change from baseline in corneal (...) fluorescence staining scores [ Time Frame: week 2, week 4 ] Corneal fluorescein staining: 2% fluorescein sodium coated with glass rods in the conjunctival sac, observed under the slit lamp to observe whether the corneal epithelium with staining, such as yellow-green stained, suggesting that corneal epithelial cell integrity damage. Score by 12 points. Cornea was divided into 4 quadrants, each quadrant was 0-3, no staining was 0, 1 to 30 dotted was 1 point, > 30 dotted but not fused For 2 points, 3 points

2017 Clinical Trials

176. A Prospective Study To Evaluate The Raindrop Near Vision Inlay In Presybopic or Pseudophakic Patients Treated With Mitomycin C Following Femtosecond Flap Creation.

, immediately following femtosecond flap creation (LASIK correction if needed), and before implantation with the Raindrop corneal inlay in the non-dominant eye. The postoperative incidence of haze, visible by broad tangential illumination of the slit lamp, is known to adversely impact the safety and efficacy of the Raindrop corneal inlay. Three main strategies have been employed to minimize haze incidence after surgery: (i) perfection of the surgical technique, (ii) deeper implantation in the cornea (...) with clinically significant anterior segment pathology. 4.3.12 Patients with any corneal abnormality, including but not limited to, slit lamp findings for corneal staining Grade 3 or higher, recurrent corneal erosion or severe basement membrane disease, and pterygium extending onto the cornea. 4.3.13 Patients with ophthalmoscopic/topographic signs of keratoconus or those who are keratoconus suspect. 4.3.14 Patients with history of Herpes zoster or Herpes simplex keratitis. 4.3.15 Pseudophakic patients

2017 Clinical Trials

177. Effect of Allopurinol for Hypoxic-ischemic Brain Injury on Neurocognitive Outcome

or hyperexcitability) Severe muscular hypotonia or hypertonia, Absent or insufficient spontaneous respiration (e.g., gasping only) with need for respiratory support at 10 min postnatally Abnormal primitive reflexes (absent suck or gag or corneal or Moro reflex) or abnormal movements (e.g., potential clinical correlates of seizure activity) Exclusion criteria gestational age below 36 weeks birth weight below 2500 g postnatal age >30min at the end of screening phase severe congenital malformation or syndrome

2017 Clinical Trials

178. Oral Flurbiprofen Spray for Mucosal Graft Harvesting at the Palatal Area

at the site of affected area, topical NSAIDs have been suggested to use. Topical flurbiprofen was reported to decrease corneal sensitivity, to effect symptomatic relief of sore throat and to reduce acute post-operative pain after oral surgical procedures in previous studies. An oral spray formulation containing 0.075 g of flurbiprofen per 30 ml spray has been developed and frequently use for the inflammatory affections of the oral cavity, pharynx and larynx. The hypotheses for this study were (...) on the experimental sites before, no smoking, no pregnancy or lactation. Exclusion Criteria: hypersensitivity to flurbiprofen, history of allergy to NSAIDs, having coagulation disorders, presence of gagging reflex. Contacts and Locations Go to No Contacts or Locations Provided More Information Go to Layout table for additonal information Responsible Party: Sıla Çağrı İşler, PhD, Gazi University ClinicalTrials.gov Identifier: Other Study ID Numbers: 36290600/66 First Posted: May 24, 2017 Last Update Posted: May 24

2017 Clinical Trials

179. A Prospective Study to Evaluate the Raindrop Near Vision Inlay With Mitomycin C

sensitivity to any planned study medications. Patients with residual, recurrent, active or uncontrolled eyelid disease. Patients with significant corneal asymmetry or irregular topography. Patients with clinically significant anterior segment pathology. Patients with any corneal abnormality, including but not limited to, slit lamp findings for corneal staining Grade 3 or higher, recurrent corneal erosion or severe basement membrane disease, and pterygium extending onto the cornea. Patients (...) suspected of having glaucoma. Patients with amblyopia or strabismus or those who are at risk for developing strabismus postoperatively as determined by corneal light reflex and cover-uncover testing. Patients with diabetic retinopathy, collagen, vascular, diagnosed autoimmune disease (e.g., lupus, rheumatoid arthritis, fibromylagia), immunodeficiency (e.g., HIV), connective tissue disease, or clinically significant atopic syndrome such as allergies or asthma. Patients on chronic systemic corticosteroid

2017 Clinical Trials

180. NMES to Improve Eyelid Functions in Cranial Nerve (CN) III and VII Palsy

additional measures of eye and corneal health. Condition or disease Intervention/treatment Phase Blepharoptosis Lagophthalmos Device: Neuromuscular electrical stimulation Device: Sham neuromuscular electrical stimulation Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 60 participants Allocation: Randomized Intervention Model: Parallel Assignment Intervention Model Description: Active treatment vs. Sham control (...) for eyelid function for 5 consecutive days just as in the experimental group, However participants do not receive the electrical stimulation. Due to the low intensity of the stimulation all participants regardless of group allocation are told they may or may not feel the electrical stimulation. Outcome Measures Go to Primary Outcome Measures : Marginal reflex distance-1 (MRD-1) [ Time Frame: Within 1 week of last treatment session. ] Measure of eyelid function for participants with CN III or CN VII palsy

2017 Clinical Trials

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>