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Corneal Reflex

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121. The Use of 3D Printing in Orbital Fractures

groups are recorded Number of subjects with a difference of more than 2 mm between the two orbits between the treatment and control groups [ Time Frame: 1 week, 3 weeks, and 6 weeks postoperatively. ] A difference of more than 2 mm between the two orbits is diagnostic for enophthalmos. Enophthalmos is assessed by clinical examination using a Hertel exophthalmometer. The measurement is taken from the lateral orbital rim to the corneal apex. The normal range is 12-21 mm. Upper normal limit for people (...) incarceration and a positive forced duction test. Immediate correction in a symptomatic patient with orbital floor ( trapdoor) fracture that has elicited the oculocardiac reflex. At least 18 years of age. Unilateral orbital floor fracture. No history of orbital trauma. Healthy contralateral orbit. Underwent orbital reconstruction. Admitted to GMH. Returned for the 6-week follow-up. Exclusion Criteria: Refuse study enrollment. Are younger than 18 years. Pregnant women. Prisoner Unable to obtain consent

2018 Clinical Trials

122. The Comparison of 50% AS Versus PFAT+ 0.05 % COE in Severe Dry Eye Syndrome

with or without preservatives) had low TBUT (< 5 s) (5μL of fluorescein sodium 2% eye drops was used) low Schirmer's test I score without topical anesthesia ( basic+reflex secretion), positive corneal and conjunctival fluorescein staining (≥grade 1 according to the OXFORD Scale) (3) and an OSDI score > 40 OSDI was a reliable and valid test for quantifying the severity of dry eye symptoms Exclusion Criteria: active ocular infection or any other inflammation not associated with dry eye a severe associated (...) : Layout table for MeSH terms Syndrome Keratoconjunctivitis Sicca Dry Eye Syndromes Disease Pathologic Processes Keratoconjunctivitis Conjunctivitis Conjunctival Diseases Eye Diseases Keratitis Corneal Diseases Lacrimal Apparatus Diseases Cyclosporins Cyclosporine Ophthalmic Solutions Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action Immunosuppressive Agents Immunologic Factors Physiological Effects of Drugs Antifungal Agents Anti-Infective Agents Dermatologic Agents Antirheumatic Agents

2018 Clinical Trials

123. Gabapentin as Preanesthetic Medication to Fast Procedures in Pediatric´s Oncology

will be submitted to the same general anesthesia protocol, receiving sevoflurane 8% plus N2O and oxygen prior to the procedure. We will record the time, in seconds, when patients lose their consciousness and corneal reflex. Levels of postoperative pain in children through Children and Infants Postoperative Pain Scale (CHIPPS). [ Time Frame: 1 hour ] After the procedure, all patients will be observed for changes in the Children and Infants Postoperative Pain Scale (CHIPPS) scores. Score changes will be assessed

2018 Clinical Trials

124. Peribulbar Block: Lidocaine-bupivacaine vs Lidocaine-bupivacaine-fentanyl

of lidocaine 5%, 15 mg of 0.5% bupivacaine and 50 mcg of fentanyl citrate for a total volume of the anesthetic mixture of 6 ml. Drug: peribulbar block 2 lidocaine/bupivacaine/fentanyl Peribulbar block: 100 mg of lidocaine 5%, 15 mg of 0.5% bupivacaine and 50 mcg of fentanyl citrate for a total volume of the anesthetic mixture of 6 ml. Other Name: lidocaine/bupivacaine/fentanyl Outcome Measures Go to Primary Outcome Measures : Latency period (lost of corneal reflex) [ Time Frame: 10 minutes until the start (...) of surgery ] lost of corneal reflex Secondary Outcome Measures : Ocular akinesia: movements of extraocular muscles [ Time Frame: 10 minutes until the start of surgery ] movements of extraocular muscles Incidence of postoperative pain [ Time Frame: 2 Hours ] Analogous visual scale postoperative complications [ Time Frame: 2 hours ] bleeding or bruise Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk

2018 Clinical Trials

125. M7824 in Consensus Molecular Subtype 4, Treatment-Refractory Metastatic Colorectal Cancer

transplantation, but with the exception of transplants that do not require immunosuppression (e.g., corneal transplant, hair transplant). Significant acute or chronic infections including, among others: a) Known history of testing positive test for human immunodeficiency virus (HIV) or known acquired immunodeficiency syndrome; b) HBV or HCV infection (HBV surface antigen positive and HBV core antibody positive with reflex to positive HBV DNA or HBV core antibody positive alone with reflex to positive HBV DNA (...) or positive HCV antibody with reflex to positive HCV RNA); c) Subjects with active tuberculosis (history of exposure or history of positive tuberculosis test plus presence of clinical symptoms, physical or radiographic findings). Active autoimmune disease that might deteriorate when receiving an immunostimulatory agent: a) Subjects with type I diabetes, vitiligo, alopecia, psoriasis, hypo- or hyperthyroid disease not requiring immunosuppressive treatment are eligible; b) Subjects requiring hormone

2018 Clinical Trials

126. Serum Neurofilament Light Chain for Prognosis of Outcome After Cardiac Arrest. (PubMed)

performance than the other biochemical serum markers (ie, tau, neuron-specific enolase, and S100). At comparable specificities, serum NFL levels had greater sensitivity for poor outcome compared with routine electroencephalogram, somatosensory-evoked potentials, head computed tomography, and both pupillary and corneal reflexes (ranging from 29.2% to 49.0% greater for serum NFL level).Findings from this study suggest that the serum NFL level is a highly predictive marker of long-term poor neurologic

2018 JAMA neurology

127. Reading Analysis in Ophthalmologic Patients

that reading ability is reduced in patients with various ocular diseases. Especially, pathologies effecting the posterior pole (central and paracentral vision) might impair reading parameters significantly. Recently, the Eyetracker Eyelink 1000 (SR Research Ltd, Canada) became available. It´s application was described previously. Briefly, a high-speed infrared camera detects the position of eye (pupil and corneal reflex) and in turn the direction of gaze 500 times per second. During the calibration process (...) Absence of ocular disease (Group 1) Present ocular disease (age-related macular degeneration, glaucoma, diabetic maculopathy, epiretinal membrane/macular hole) as judged by the investigator (Group 2 - 5) Maximum of allowed cylinder-power in the spectacles: +1.50D Exclusion Criteria: Ocular pathologies, that may interfere with study measurements, such as corneal scars In case of pregnancy (pregnancy test will be taken prior to inclusion into the study in women of reproductive age) Contacts

2018 Clinical Trials

128. Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination

-Pupillary light reflex with bright light. 3-Corneal reflexes with the use of cotton swab or tissue paper. 4-Gag reflex with a tongue depressor looking for bilateral palatal elevation. 5-Cough with tracheal suctioning at the carinal level) and GCS re-evaluated Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more

2018 Clinical Trials

129. TRPV1 and TRPM8 Channels and Nocifensive Behavior in a Rat Model for Dry Eye. (Full text)

TRPV1 and TRPM8 Channels and Nocifensive Behavior in a Rat Model for Dry Eye. Persistent ocular surface pain occurs in moderate to severe dry eye disease (DE); however, the mechanisms that underlie this symptom remain uncertain. The aim of this study was to determine if the transient receptor potential vanilloid ion channels play a role in hypertonic saline (HS)-evoked corneal reflexes in a model for aqueous tear deficient DE.Eye wipe behavior and orbicularis oculi muscle activity (OOemg) were (...) to target specific transducer molecules on corneal nerves may prove beneficial as adjunct therapies in managing ocular pain in moderate to severe cases of DE.

2018 Investigative Ophthalmology & Visual Science PubMed

130. A holographic waveguide based eye tracker (Full text)

collimator. The waveguide captured images of the anterior segment of the eye right in front of it and guided the images to a processing unit distant from the eye. The vector connecting the pupil center (PC) and the corneal reflex (CR) of the eye was used to compute eye position in the socket. An eye model, made of a high quality prosthetic eye, was used prototype validation. The benchtop prototype demonstrated a linear relationship between the angular eye position and the PC/CR vector over a range of 60

2018 Proceedings of SPIE--the International Society for Optical Engineering PubMed

131. A Case of Neurotrophic Keratopathy Concomitant to Brain Metastasis (Full text)

A Case of Neurotrophic Keratopathy Concomitant to Brain Metastasis We report a case of a 63-year-old Caucasian female referred to the cornea service of Clinica Oculistica with a neurotrophic corneal ulcer, decreased corneal sensitivity, absent corneal reflex, and decreased lacrimation. The medical record review was relevant for mastectomy and adjuvant therapy for breast cancer complicated by pontocerebellar angle metastasis. Eye patching and application of antibiotic and vitamin ointments were (...) prescribed at first, without a significant improvement. Thus, treatment with autologous serum was started. In about two weeks, the cornea recovered and visual acuity improved with a residual corneal scarring. Finally, we should mention that, in our case, the main cause of the neurotrophic corneal ulcer could be identified in the previous trigeminal damage at the pontocerebellar angle and trigeminal ganglion. Sensory nerves play an important regulatory role via neuro-mediators on corneal wound healing

2018 Cureus PubMed

132. Suction Stability Management in SMILE: Development of a Decision Tree for Managing Eye Movements and Suction Loss. (PubMed)

movements. A decision tree protocol was developed to define the management in each scenario depending on the suction stability grading and the femtosecond laser cutting progress.Eight types of eye movement were identified: fixation light tracking, Bell's reflex, saccades, oscillations, anxiety/uncooperative patient, nociceptive reflex movement, false suction, and nystagmus. Type I eye movements were defined as small movements that shift the corneal position by a clinically negligible amount. The surgeon (...) may want to pause the femtosecond laser cutting, regain control of the patient, then continue. Type II eye movements were defined as large movements that shift the corneal position by a clinically relevant amount, in which case the surgeon may choose to release suction (ie, a surgeon-initiated suction loss). Type III eye movements were defined as those with sufficient force to break suction (ie, a patient-generated suction loss). A comprehensive decision tree was developed to cover all possible

2018 Journal of Refractive Surgery

133. The Anticipated Organ Donation Approach

or Female over 18 years-old patients with serious brain damages medical decision of withdrawing life sustaining treatment Signed and dated informed consent by trusted person, or family Patient covered by social security regimen Glasgow Coma Scale (GCS) : Patient with serious brain-injured without confounding factors, without head trauma or brain anoxia : GCS<5 and loss of the corneal reflex or GCS<5 and loss of the brainstem reflex Patient with serious brain-injured with confounding factors, without (...) head trauma and brain anoxia : GCS<7 with a least one scanographic sign of gravity Deletion of the subarachnoid cisterns Deviation of the median line of more than 15 mm Hematoma volume < 65 cm3 Secondary hydrocephalus to an intra-ventricular bleeding with V3 or V4 flood. o Patient with head trauma or brain anoxia (no confounding factor) with reliable clinical examination required : GCS<5 and loss of the corneal reflex or GCS<5 and loss of the brainstem reflex Exclusion Criteria: No trusted person

2018 Clinical Trials

134. Local Anaesthesia in Ophthalmic Surgery

monitoring and management of complications are met. For surgical procedures using topical local anaesthesia, protocols should be locally agreed. Non-medical staff should not administer LA blocks for complex procedures such as difficult cataracts, strabismus, vitreoretinal, glaucoma, oculoplastic and corneal transplant surgery. These patients often have significant co-morbidities and the procedures are generally more prolonged. These patients may also have higher risk of ocular and systemic complications

2012 Royal College of Ophthalmologists

136. Local anaesthesia for ophthalmic surgery

monitoring and management of complications are met. For surgical procedures using topical local anaesthesia, protocols should be locally agreed. Non-medical staff should not administer LA blocks for complex procedures such as difficult cataracts, strabismus, vitreoretinal, glaucoma, oculoplastic and corneal transplant surgery. These patients often have significant co-morbidities and the procedures are generally more prolonged. These patients may also have higher risk of ocular and systemic complications

2012 Royal College of Anaesthetists

137. Squint in children

tests to confirm the presence of a squint in primary care include general inspection of the eyes, the corneal light reflex test, and cover tests. General clinical assessment is important to detect a serious underlying disorder that may present as a squint. In addition, testing the red reflex can help to exclude rare serious intraocular disease such as retinoblastoma. Any child with a suspected or confirmed squint should be referred to the paediatric eye service for management (urgently if a serious (...) . The corneal light reflex test (Hirschberg test). To do this, have the child fixate on a light (for example, a pen torch) held about 50 cm in front of their eyes. Observe the light that reflects back from their corneas which is normally in the same place on both corneas. Any asymmetry of the reflected light suggests a squint. Cover tests. These are done whilst the child views an object, such as a toy, at 33 cm away from their eyes: The cover test for manifest squint: whilst fixation is maintained (which

2016 NICE Clinical Knowledge Summaries

138. Red eye

swelling and corneal ulceration demonstrated by fluorescein. For more information, see the CKS topic on . In corneal foreign body , there is often a prior history of wind blowing a foreign body into the eye, or the use of hammering or grinding tools. Symptoms include foreign body sensation, pain, and photophobia. A corneal foreign body may be seen on examination. Visual acuity and pupil reflexes are usually normal. For more information, see the CKS topic on . Anterior uveitis. This is inflammation (...) the cornea meets the sclera) are injected, is seen in more serious causes of red eye, such as anterior uveitis and corneal causes. Perform fluorescein examination. If the cornea stains this can be an indication that a corneal abrasion or ulcer is present. Check pupil reactions, using the brightest light source possible. Check if the person is photophobic. Observe pupil size and shape. Check direct and consensual pupillary reflexes. Check the person's blood pressure, if subconjunctival haemorrhage

2016 NICE Clinical Knowledge Summaries

139. A Study to Evaluate the Raindrop Near Vision Inlay Under Flap or Within Pocket

with high pressures during suction application. 1.1.15 Patients with known history of steroid-responsive intraocular pressure increases, glaucoma, preoperative IOP > 21 mm Hg, or are otherwise suspected of having glaucoma. 1.1.16 Patients with amblyopia or strabismus or those who are at risk for developing strabismus postoperatively as determined by corneal light reflex and cover-uncover testing. 1.1.17 Patients with diabetic retinopathy, collagen, vascular, diagnosed autoimmune disease (e.g., lupus (...) : December 18, 2017 See Sponsor: Whitten Laser Eye Information provided by (Responsible Party): Whitten Laser Eye Study Details Study Description Go to Brief Summary: The objective of this study is to evaluate the Raindrop® Near Vision Inlay for the improvement of near vision in presbyopes implanted under a corneal flap or within a small-incision pocket. Condition or disease Intervention/treatment Phase Presbyopia Device: Raindrop Near Vision Inlay Phase 4 Detailed Description: Patients must require

2017 Clinical Trials

140. Epidermoid cysts of the cavernous sinus: clinical features, surgical outcomes, and literature review. (Full text)

with CS epidermoid cysts that had been surgically treated at the authors' hospital between 2001 and 2016. The patients' medical records, imaging data, and follow-up outcomes were retrospectively analyzed. The related literature from the past 40 years (18 articles, 20 patients) was also evaluated.The most common chief complaints were facial numbness or hypesthesia (64.5%), absent corneal reflex (45.2%), and abducens or oculomotor nerve deficit (35.5%). On MRI, 51.6% of the epidermoid cysts showed low

2017 Journal of Neurosurgery PubMed

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