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Corneal Reflex

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181. TFOS DEWS II pain and sensation report Full Text available with Trip Pro

and reflex blinking. ViVc ocular neurons project to brain regions that control lacrimation and spontaneous blinking and to the sensory thalamus. Secretion of the main lacrimal gland is regulated dominantly by autonomic parasympathetic nerves, reflexly activated by eye surface sensory nerves. These also evoke goblet cell secretion through unidentified efferent fibers. Neural pathways involved in the regulation of meibomian gland secretion or mucin release have not been identified. In dry eye disease (...) of molecular, structural and functional disturbances in ocular sensory pathways ultimately leads to dysestesias and neuropathic pain referred to the eye surface. Pain can be assessed with a variety of questionaires while the status of corneal nerves is evaluated with esthesiometry and with in vivo confocal microscopy.Copyright © 2017 Elsevier Inc. All rights reserved.

2017 The ocular surface

182. Eosinophilic granuloma at the cerebellopontine angle in an adult; a rare case report and literature review Full Text available with Trip Pro

man was being evaluated in our neuro-oncology clinic due to diplopia since 4 months ago. On physical examination he had left sided abducens paresis, hyposthesia over left half of his face and a decreased corneal reflex on left side. A magnetic resonance imaging (MRI) study revealed a lesion at left CP angle measuring 30×25×25mm in size which was isointense in T1, hypointense on T2 with homogenous enhancement in post-contrast study. A standard retrosigmoid approach was carried out for resection

2017 International journal of surgery case reports

183. A Prospective Study to Evaluate the Raindrop Near Vision Inlay With Mitomycin C

sensitivity to any planned study medications. Patients with residual, recurrent, active or uncontrolled eyelid disease. Patients with significant corneal asymmetry or irregular topography. Patients with clinically significant anterior segment pathology. Patients with any corneal abnormality, including but not limited to, slit lamp findings for corneal staining Grade 3 or higher, recurrent corneal erosion or severe basement membrane disease, and pterygium extending onto the cornea. Patients (...) suspected of having glaucoma. Patients with amblyopia or strabismus or those who are at risk for developing strabismus postoperatively as determined by corneal light reflex and cover-uncover testing. Patients with diabetic retinopathy, collagen, vascular, diagnosed autoimmune disease (e.g., lupus, rheumatoid arthritis, fibromylagia), immunodeficiency (e.g., HIV), connective tissue disease, or clinically significant atopic syndrome such as allergies or asthma. Patients on chronic systemic corticosteroid

2017 Clinical Trials

184. A Study to Evaluate the Raindrop Near Vision Inlay Under Flap or Within Pocket

for corneal staining Grade 3 or higher, recurrent corneal erosion or severe basement membrane disease, and pterygium extending onto the cornea. 1.1.12 Patients with ophthalmoscopic/topographic signs of keratoconus or those who are keratoconus suspect. 1.1.13 Patients with history of Herpes zoster or Herpes simplex keratitis. 1.1.14 Patients with any progressive retinal disease or patients with a history or evidence of retinal vascular occlusion and/or hypercoagulability, because of the risks associated (...) with high pressures during suction application. 1.1.15 Patients with known history of steroid-responsive intraocular pressure increases, glaucoma, preoperative IOP > 21 mm Hg, or are otherwise suspected of having glaucoma. 1.1.16 Patients with amblyopia or strabismus or those who are at risk for developing strabismus postoperatively as determined by corneal light reflex and cover-uncover testing. 1.1.17 Patients with diabetic retinopathy, collagen, vascular, diagnosed autoimmune disease (e.g., lupus

2017 Clinical Trials

185. A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopic Patients With Treatments to Optimize the Ocular Surface Before Implantation

, recurrent corneal erosion or severe basement membrane disease, and pterygium extending onto the cornea. 1.2.13 Patients with ophthalmoscopic/topographic signs of keratoconus or those who are keratoconus suspect. 1.2.14 Patients with history of Herpes zoster or Herpes simplex keratitis. 1.2.15 Patients with any progressive retinal disease or subjects with a history or evidence of retinal vascular occlusion and/or hypercoagulability, because of the risks associated with high pressures during suction (...) application. 1.2.16 Patients with known history of steroid-responsive intraocular pressure increases, glaucoma, preoperative IOP > 21 mm Hg, or are otherwise suspected of having glaucoma. 1.2.17 Patients with amblyopia or strabismus or those who are at risk for developing strabismus postoperatively as determined by corneal light reflex and cover-uncover testing. 1.2.18 Patients with diabetic retinopathy, collagen, vascular, diagnosed autoimmune disease (e.g., lupus, rheumatoid arthritis, fibromylagia

2017 Clinical Trials

186. Walnut Shell Glasses Moxibustion for Dry Eye Syndrome

three times to take the mean. change from baseline in SchimerⅠtext [ Time Frame: week 2, week 4 ] Evaluation the tear secretion, do not use ocular surface anesthetic, measuring the amount of reflex tear secretion. Place the test paper in the middle and outer 1/3 of the conjunctiva of the lower eyelid, and instruct the patient to lighten his eyes or look down at the bottom, and remove it after 5 minutes to measure the wetness from the beginning of the bend. change from baseline in corneal (...) fluorescence staining scores [ Time Frame: week 2, week 4 ] Corneal fluorescein staining: 2% fluorescein sodium coated with glass rods in the conjunctival sac, observed under the slit lamp to observe whether the corneal epithelium with staining, such as yellow-green stained, suggesting that corneal epithelial cell integrity damage. Score by 12 points. Cornea was divided into 4 quadrants, each quadrant was 0-3, no staining was 0, 1 to 30 dotted was 1 point, > 30 dotted but not fused For 2 points, 3 points

2017 Clinical Trials

187. Inhaled Nitric Oxide After Out-of-Hospital Cardiac Arrest

Inclusion Criteria: Intubated and comatose adult (>18 yo) resuscitated from out-of-hospital cardiac arrest (OHCA)* *Cardiac arrest within an emergency department or outpatient medical center will be included). OHCA includes Emergency Medical Service (EMS) witnessed cardiac arrest. Return of spontaneous circulation (ROSC) within 40 min of CPR initiation Full Outline of Unresponsiveness (FOUR) Brainstem score ≥ 2 (i.e. patient must have pupil OR corneal reflex at the time of ED presentation or within 1h

2017 Clinical Trials

188. Effect of Allopurinol for Hypoxic-ischemic Brain Injury on Neurocognitive Outcome

or hyperexcitability) Severe muscular hypotonia or hypertonia, Absent or insufficient spontaneous respiration (e.g., gasping only) with need for respiratory support at 10 min postnatally Abnormal primitive reflexes (absent suck or gag or corneal or Moro reflex) or abnormal movements (e.g., potential clinical correlates of seizure activity) Exclusion criteria gestational age below 36 weeks birth weight below 2500 g postnatal age >30min at the end of screening phase severe congenital malformation or syndrome

2017 Clinical Trials

189. Oral Flurbiprofen Spray for Mucosal Graft Harvesting at the Palatal Area

at the site of affected area, topical NSAIDs have been suggested to use. Topical flurbiprofen was reported to decrease corneal sensitivity, to effect symptomatic relief of sore throat and to reduce acute post-operative pain after oral surgical procedures in previous studies. An oral spray formulation containing 0.075 g of flurbiprofen per 30 ml spray has been developed and frequently use for the inflammatory affections of the oral cavity, pharynx and larynx. The hypotheses for this study were (...) on the experimental sites before, no smoking, no pregnancy or lactation. Exclusion Criteria: hypersensitivity to flurbiprofen, history of allergy to NSAIDs, having coagulation disorders, presence of gagging reflex. Contacts and Locations Go to No Contacts or Locations Provided More Information Go to Layout table for additonal information Responsible Party: Sıla Çağrı İşler, PhD, Gazi University ClinicalTrials.gov Identifier: Other Study ID Numbers: 36290600/66 First Posted: May 24, 2017 Last Update Posted: May 24

2017 Clinical Trials

190. Is Anesthetic Loss of Consciousness a Top Down or Bottom up Phenomenon. What Does the Neurologic Examination Say?.

ke0 1,21 min-1 using a calculated target of 5.4 ug/ml (loss of counsciousness EC95) and slow induction (GL) 10 mg/kg/h with calculated effect site concentrations (CeCALC) same PK model. The same neurologist, blind to the correspondent group, evaluated all the patients every 30 sec using the coma FOUR scale until loss of counsciousness (LOC), defined as a FOUR (E0 no eyes opening response and /or M0 no motor response). At LOC the existance of brainstem reflex was evaluated (B no pupil and corneal (...) reflex), respiratory pattern (R apnoea), CeCALC and patient state index (PSI) SEDline™ was recorded during all the examination. After LOC in both groups we maintain in GR the initial target (5.3 ug/ml) and the LOC CeCALC during 10 min without intervention, except respiratory support if it was required. Frontal EEG 4 channel and spectrogram from SEDline monitor was extracted for each case and posterior analysis. Fisher exact test was used to describe primary outcome and difference between B and R

2017 Clinical Trials

191. Effects of Two Tear Substitutes in Patients With Dry Eye Syndrome

is 1-2 Exclusion Criteria: Any corneal,conjunctival, or eyelid abnormalities; conjunctivitis; current ocular infection; photophobia that may cause reflex tearing or difficulty in evaluating the patien 's lipid layer; Known allergic sensitivity to any of the ingredients in Liposic or Tears Naturale Forte Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information (...) of the participant recieved Tears Naturale Forte Other Name: DEXTRAN/HYPROMELLOSE/GLYCERIN Outcome Measures Go to Primary Outcome Measures : scale of Schirmer I test [ Time Frame: up to 3 months after tear substitutes apply ] scale of corneal fluorescein staining [ Time Frame: up to 3 months after tear substitutes apply ] scale of noninvasive tear breakup time [ Time Frame: up to 3 months after tear substitutes apply ] scale of tear meniscus height [ Time Frame: up to 3 months after tear substitutes apply

2017 Clinical Trials

192. A Prospective Study To Evaluate The Raindrop Near Vision Inlay In Presybopic or Pseudophakic Patients Treated With Mitomycin C Following Femtosecond Flap Creation.

, immediately following femtosecond flap creation (LASIK correction if needed), and before implantation with the Raindrop corneal inlay in the non-dominant eye. The postoperative incidence of haze, visible by broad tangential illumination of the slit lamp, is known to adversely impact the safety and efficacy of the Raindrop corneal inlay. Three main strategies have been employed to minimize haze incidence after surgery: (i) perfection of the surgical technique, (ii) deeper implantation in the cornea (...) with clinically significant anterior segment pathology. 4.3.12 Patients with any corneal abnormality, including but not limited to, slit lamp findings for corneal staining Grade 3 or higher, recurrent corneal erosion or severe basement membrane disease, and pterygium extending onto the cornea. 4.3.13 Patients with ophthalmoscopic/topographic signs of keratoconus or those who are keratoconus suspect. 4.3.14 Patients with history of Herpes zoster or Herpes simplex keratitis. 4.3.15 Pseudophakic patients

2017 Clinical Trials

193. NMES to Improve Eyelid Functions in Cranial Nerve (CN) III and VII Palsy

additional measures of eye and corneal health. Condition or disease Intervention/treatment Phase Blepharoptosis Lagophthalmos Device: Neuromuscular electrical stimulation Device: Sham neuromuscular electrical stimulation Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 60 participants Allocation: Randomized Intervention Model: Parallel Assignment Intervention Model Description: Active treatment vs. Sham control (...) for eyelid function for 5 consecutive days just as in the experimental group, However participants do not receive the electrical stimulation. Due to the low intensity of the stimulation all participants regardless of group allocation are told they may or may not feel the electrical stimulation. Outcome Measures Go to Primary Outcome Measures : Marginal reflex distance-1 (MRD-1) [ Time Frame: Within 1 week of last treatment session. ] Measure of eyelid function for participants with CN III or CN VII palsy

2017 Clinical Trials

194. Small Incision Lenticule Extraction (SMILE) for Hyperopia: Optical Zone Centration. (Abstract)

) and astigmatism up to 6.00 D. For SMILE, the optical zone was between 6.3 and 6.7 mm, with a 2-mm transition zone. Two LASIK control groups (6.5- and 7-mm optical zone) were generated matched for spherical equivalent treated. In SMILE, the corneal vertex of the coaxially fixating eye was aligned with the vertex of the curved contact glass. In LASIK, the treatment was centered on the coaxially sighted corneal light reflex (first Purkinje image) with the contralateral eye (Seiler method). A tangential (...) (instantaneous) curvature preoperative to 3 months postoperative difference map was generated for each eye. A fixed grid and set of concentric circles were superimposed on the difference map to measure the offset between the optical zone center and corneal vertex (0,0), and vector analysis was used for comparative analysis.Mean attempted spherical equivalent was +5.61 ± 0.96 D (range: +3.20 to +6.50 D) and mean cylinder was -0.96 ± 0.62 D (range: 0.00 to -2.75 D) in the SMILE group. Mean age was 29 ± 7 years

2017 Journal of Refractive Surgery

195. Electroencephalography Predicts Poor and Good Outcomes After Cardiac Arrest: A Two-Center Study. Full Text available with Trip Pro

than 70% positive predictive value for good outcome; reactivity (80.4%; 95% CI, 75.9-84.4%) and motor response (80.1%; 95% CI, 75.6-84.1%) had highest accuracy. Early benign electroencephalography heralded good outcome in 86.2% (95% CI, 79.8-91.1%). False positive rates for mortality were less than 5% for epileptiform or nonreactive early electroencephalography, nonreactive late electroencephalography, absent somatosensory-evoked potential, absent pupillary or corneal reflexes, presence

2017 Critical Care Medicine

196. Outcome after Hunt and Hess Grade V subarachnoid hemorrhage: a comparison of pre-coiling era (1980-1995) versus post-ISAT era (2005-2014). (Abstract)

treatment resulted in a significant improvement in survival rate (NNT = 2) and favorable outcome (NNT = 3 for mRS score of 0-3) for comatose patients with Hunt and Hess Grade V SAH compared with the earlier period. Independent predictors for favorable outcome were younger age and bilateral intact corneal reflexes. Despite a high rate of cerebral infarction (65%) in the current period, 29.5% of the patients who received treatment for their aneurysms during the current era (2005-2014) had a favorable

2017 Journal of Neurosurgery

197. Development of a Chromatic Pupillography Protocol for the First Gene Therapy Trial in Patients With CNGA3-Linked Achromatopsia. Full Text available with Trip Pro

the pupillary light reflex parameters and to create the final protocol. In the individual protocols, various stimulus parameters (i.e., intensity, duration, wavelength, adaptation states) were applied to evaluate the impact of these stimuli on the pupillary response in untreated ACHM patients.In the light-adapted conditions, CNGA3-ACHM patients showed significantly reduced maximal amplitudes compared with the control group when using a 1-second high intensity (28-lux corneal illumination) blue or red (...) stimulus (P < 0.005). In the dark-adapted conditions, CNGA3-ACHM patients unexpectedly revealed significantly increased maximal amplitudes when stimulating with red (1 second) or blue (4 ms and 1 second) stimuli of low intensity (0.01-lux corneal illumination; P < 0.05). Pupil responses of CNGA3-ACHM patients after high intensity (28 lux) red and blue 1-second stimuli were within the normal range.Chromatic pupillography demonstrated significant reduced pupil responses to stimuli addressing primarily

2017 Investigative Ophthalmology & Visual Science

198. Patient Dignity (Formerly:Patient Modesty):Volume 102

ABUSE SUFFERED BY JR AND HER HUSBAND; YOUR GRANDCHILDREN WHO MAY HAVE SOME HEALTH ISSUES OR DISABILTIES THAT PREVENT THEM FROM WORKING, WILL BE THE FIRST TO “VOLUNTEER” THEIR CORNEAS OR KIDNEYS OR WHATEVER THE MAKEMSICK ‘EXPERTS’ DEEM IS ‘NEEDED.’ Come on, we now have medical kidnappings; forcibly subjecting (mainly children) to bogus treatments such as chemotherapy, which latest literature reveals to CAUSE CANCER IN HEALTHY CELLS! But, if the makemsick industry can make $300-$500,000 per victim

2019 Bioethics Discussion Blog

199. Miosis

exposed eye associated parasympathetic fibers signal opposite iris to constrict Accommodation Visual focusing Near Reaction (e.g. Reading) Also results in eye convergence (under control as well) Pathway Ciliary body smooth muscle contracts Lens changes shape (more convex) constricts during accommodation to aid focusing Both ciliary body contraction and Pupil Constriction are mediated by related parasympathetic fibers Visual cortex controls accommodation as part of a reflex loop based on signals III (...) užívají léky, které ji vyvolávají – miotika. Opak mydriáza. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ ) Definition (MSH) Pupillary constriction. This may result from congenital absence of the dilatator pupillary muscle, defective sympathetic innervation, or irritation of the CONJUNCTIVA or CORNEA. Concepts Finding ( T033 ) MSH ICD9 379.42 SnomedCT 194166000 , 61514009 , 63251006 English Mioses , Miosis , MIOSIS , PUPILS CONSTRICTED , Small pupil , Miosis disorder

2018 FP Notebook

200. Eye Examination Signs of Chemical Dependency

: Abnormal Extraocular Movements Fails to hold gaze (PCP) - may occur Abnormal Convergence (unable to hold crossed eyes) s V. Exam: Abnormal Corneal Reflex (Decreased rate of blinking) (PCP) VI. Exam: Abnormal Retinal Exam Talc retinopathy (talc used to cut IV drugs) Peri- r vessels show white retractile spots VII. Exam: Corneal defects Keratopathy or s Associated with crack smoking VIII. Contributors Paul Rock, OD at Outer Banks Eye Care IX. Reference Images: Related links to external sites (from Bing

2018 FP Notebook

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