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21. Cataract incision-related corneal erosion: recurrent corneal erosion as a result of clear corneal cataract surgery. (Abstract)

Cataract incision-related corneal erosion: recurrent corneal erosion as a result of clear corneal cataract surgery. Three patients developed recurrent corneal erosions over their cataract surgery corneal incisions. These cataract incision-related corneal erosions resulted in pain following cataract surgery. None had any physical findings for corneal erosion, thus a novel technique called the corneal sweep test was developed to identify the erosion. To the authors' knowledge, this is the first (...) time this association between the clear corneal cataract incision and recurrent corneal erosions has been reported. Considering the high number of cataract surgery performed around the world, it is important for ophthalmologists to recognize cataract incision-related corneal erosions as a potential cause of ocular discomfort after clear corneal cataract surgery.

2020 Journal of cataract and refractive surgery

22. Accelerated contact lens-assisted corneal crosslinking and piggyback modification in a pediatric case with advanced keratoconus and thin cornea. (Abstract)

Accelerated contact lens-assisted corneal crosslinking and piggyback modification in a pediatric case with advanced keratoconus and thin cornea. A 14-year-old girl presented with bilateral keratoconus (KC). Maximum keratometry (Kmax) was 63.9 diopter (D) in the right eye and 63.7 D in the left eye. Minimum corneal thickness was 371 μm in the right eye and 370 μm in the left. The right eye underwent epithelium-off accelerated corneal crosslinking (CXL) using hypo-tonic dextran-free 0.1 (...) and effective treatment in this pediatric KC case with thin cornea.

2020 Journal of cataract and refractive surgery

23. Are Topical Nonsteroidal Anti-Inflammatory Drugs Useful for Analgesia in Patients With Traumatic Corneal Abrasions? Full Text available with Trip Pro

Are Topical Nonsteroidal Anti-Inflammatory Drugs Useful for Analgesia in Patients With Traumatic Corneal Abrasions? Are Topical Nonsteroidal Anti-Inflammatory Drugs Useful for Analgesia in Patients With Traumatic Corneal Abrasions? - Annals of Emergency Medicine Email/Username: Password: Remember me Search Terms Search within Search Share this page Access provided by Volume 73, Issue 2, Pages 157–159 Are Topical Nonsteroidal Anti-Inflammatory Drugs Useful for Analgesia in Patients (...) With Traumatic Corneal Abrasions? x Jason R. West , MD (EBEM Commentator) Department of Emergency Medicine, Lincoln Medical and Mental Health Center, Bronx, NY DOI: | Publication History Published online: December 04, 2018 Expand all Collapse all Article Outline Take-Home Message There is no strong evidence to suggest that topical nonsteroidal anti-inflammatory drugs provide adequate analgesia for patients with traumatic corneal abrasions, yet there is low-quality evidence to suggest that the drugs decreased

2019 Annals of Emergency Medicine Systematic Review Snapshots

24. Cenegermin (Oxervate) - for the treatment of moderate (persistent epithelial defect) or severe (corneal ulcer) neurotrophic keratitis in adults

Cenegermin (Oxervate) - for the treatment of moderate (persistent epithelial defect) or severe (corneal ulcer) neurotrophic keratitis in adults Search Page - Drug and Health Product Register Language selection Search and menus Search Search website Search Topics menu You are here: Summary Basis of Decision - - Health Canada Expand all Summary Basis of Decision (SBD) for Contact: Summary Basis of Decision (SBD) documents provide information related to the original authorization of a product

2019 Health Canada - Drug and Health Product Register

25. [Corneal collagen cross-linking and intrastromal corneal ring segments in the treatment of corneal ectasia]

: Haute Autorité de Santé (HAS). 2015 Authors' conclusions These two procedures are presented as an alternative to corneal transplant. The expected effects are stabilisation of the disease from corneal collagen cross-linking (CXL), and visual rehabilitation from placement of intrastromal corneal ring segments (ICRS). Final publication URL INAHTA brief and checklist INAHTA brief and checklist Indexing Status Subject indexing assigned by CRD MeSH Collagen; Cornea; Corneal Diseases; Dilatation (...) [Corneal collagen cross-linking and intrastromal corneal ring segments in the treatment of corneal ectasia] Crosslinking du collagène cornéen et anneaux intra-cornéens dans le traitement des ectasies cornéennes [Corneal collagen cross-linking and intrastromal corneal ring segments in the treatment of corneal ectasia] Crosslinking du collagène cornéen et anneaux intra-cornéens dans le traitement des ectasies cornéennes [Corneal collagen cross-linking and intrastromal corneal ring segments

2015 Health Technology Assessment (HTA) Database.

26. Corneal hydrops

to keratoconus with intracameral injection of sulfur hexafluoride (SF6). Cornea 2007;26:1067- 9 Rowson NJ, Dart JK, Buckley RJ. Corneal neovascularisation in acute hydrops. Eye 1992;6:404-6 Sharma N, Maharana PK, Jhanji V, Vajpayee RB. Management of acute corneal hydrops in ectatic corneal disorders. Curr Opin Ophthalmol. 2012;23(4):317-23 Lay summary This is a rare occurrence seen occasionally in people in whom the cornea (the clear window of the eye) is thinned and distorted, for example in the condition (...) Corneal hydrops Corneal hydrops submit The College submit You're here: Corneal hydrops Corneal hydrops The CMGs are guidelines on the diagnosis and management of a range of common and rare, but important, eye conditions that present with varying frequency in primary and first contact care. Share options Aetiology Rupture of Descemet’s membraneAcute leakage of aqueous into corneal stroma and epithelium Predisposing factors Keratoconus, keratoglobus, pellucid marginal degeneration or other

2020 College of Optometrists

27. Corneal abrasion

by failure of the normal blink reflex, or when its sensitivity to touch is reduced by damage to its nerves, as in diabetes or following shingles of the eye. Corneal abrasion can be very painful as the cornea is one of the most sensitive areas of the body. The clinician will assess the area involved and prescribe treatment accordingly. The damage to the surface can be seen more easily if fluorescein, an orange dye, is instilled into the eye. Anti-inflammatory or antibiotic eye drops are often recommended (...) Corneal abrasion Corneal abrasion submit The College submit You're here: Corneal abrasion Corneal abrasion The CMGs are guidelines on the diagnosis and management of a range of common and rare, but important, eye conditions that present with varying frequency in primary and first contact care. Share options Aetiology Loss of corneal epithelial tissue due to: sub-tarsal foreign body trauma (e.g. fingernail, twig, edge of paper, mascara brush) contact lens related trauma trichiasis (e.g. lash

2020 College of Optometrists

28. Corneal (Foreign Body)

body can be irrigated away with normal saline Foreign body on conjunctiva can be removed with a sterile cotton bud Assess depth of corneal foreign body (slit lamp optical section) Carry out Seidel test to check for corneal perforation Corneal foreign body may require removal with a hypodermic needle or other disposable instrument. To reduce the risk of corneal penetration, ensure that the needle approaches the cornea tangentially After removal, assess size of remaining epithelial defect so (...) Corneal (Foreign Body) Corneal (or other superficial ocular) foreign body submit The College submit You're here: Corneal (or other superficial ocular) foreign body Corneal (or other superficial ocular) foreign body The CMGs are guidelines on the diagnosis and management of a range of common and rare, but important, eye conditions that present with varying frequency in primary and first contact care. Share options Aetiology Patient often gives history of foreign body entering eye wind blown high

2020 College of Optometrists

29. Fuchs Corneal dystrophy

be asymmetrical) Central cornea affected (may extend to periphery in time) excrescences on posterior surface (guttata) produce ‘beaten metal’ appearance and interrupt specular image of endothelium thickened Descemet’s membrane fine pigment dusting on endothelium cystic epithelial oedema, ground glass appearance (bullous keratopathy) stromal oedema and thickening (endothelial decompensation) posterior stromal scarring Loss of contrast sensitivity Reduced corneal sensitivity The stages of Fuchs Dystrophy have (...) been graded by a number of authorities, but none have gained universal acceptance Differential diagnosis Pseudophakic or aphakic bullous keratopathy Posterior polymorphous dystrophy Cornea guttata (often listed as a dystrophy, but not necessarily progressive) Corneal hydrops (in keratoconus) Contact lens overwear Management by optometrist Practitioners should recognise their limitations and where necessary seek further advice or refer the patient elsewhere Non pharmacological Photography

2020 College of Optometrists

30. [Clinical comparison analysis in surgically induced astigmatism of the total, anterior and posterior cornea after 2.2-mm versus 3.0-mm clear corneal incision cataract surgery]. (Abstract)

[Clinical comparison analysis in surgically induced astigmatism of the total, anterior and posterior cornea after 2.2-mm versus 3.0-mm clear corneal incision cataract surgery]. Objective: To compare the surgical induced astigmatism(SIA) of the total, anterior and posterior cornea between eyes with 2.2-mm and 3.0-mm clear corneal incisions in phacoemulsification. Methods: A prospective double-blind randomized controlled study was conducted on 131 patients (131 eyes) with age-related cataract (...) ±0.42) D, P<0.01] and 3.0-mm group [(-0.58±0.66) vs. (-0.37±0.42) D, P<0.01]. Conclusions: Compared with the 3.0-mm incision, the 2.2-mm coaxial micro-incision cataract surgery has a lower and more stable SIA. The effect of a clear corneal incision in cataract surgery on the total cornea is more obvious than that on the anterior surface of the cornea. The difference is significant in the early stage and gradually decrease with time. (Chin J Ophthalmol, 2019, 55: 495-501).

2019 [Zhonghua yan ke za zhi] Chinese journal of ophthalmology Controlled trial quality: uncertain

31. Individualized penetrating keratoplasty using edge-trimmed glycerol-preserved donor corneas for perforated corneal ulcers. Full Text available with Trip Pro

Individualized penetrating keratoplasty using edge-trimmed glycerol-preserved donor corneas for perforated corneal ulcers. To report a surgical technique and the surgical outcomes of individualized penetrating keratoplasty (PK) using edge-trimmed glycerol-preserved donor corneas for perforated corneal ulcers.Fourteen perforated eyes from 14 patients who underwent individualized PK using edge-trimmed glycerol-preserved donor corneas, were included in the retrospective study. The perforations (...) were mainly 1-2 mm in size except for one that was 2.5 × 4 mm. Three patients were treated with PK; one patient was treated with PK and a conjunctival flap; ten patients who had large ulcer areas were treated with PK combined with lamellar keratoplasty (LK). Donor corneas were preserved in sterile pure glycerol at - 80 °C. Corneal grafts were specially edge-trimmed to match the perforation, and then sutured onto the recipient bed avoiding the visual axis.All 14 patients recovered anatomical

2019 BMC Ophthalmology

32. Influence of peripheral corneal relaxing incisions during cataract surgery for corneal astigmatism up to 2.5 dioptres on corneal densitometry. Full Text available with Trip Pro

Influence of peripheral corneal relaxing incisions during cataract surgery for corneal astigmatism up to 2.5 dioptres on corneal densitometry. To assess the effect of peripheral corneal relaxing incisions (PCRI) for astigmatism between 0.75 and 2.5 dioptres during cataract surgery on corneal densitometry (CD).In this prospective, randomised study, 80 eyes (80 patients), received either tIOL or PCRI. Assessment at pre-operative and 1, 3, 6, 12 months post-operative visit included uncorrected (...) thereafter. For zones 1, 2 and 3, CD significantly reduced after 3 months with tIOLs whereas with PCRIs, it reduced 1 month onwards. For zone 4, CD reduced only at 12 months with tIOLs compared to 3 months onwards with PCRIs. In both groups CD was higher in the zone 4 and anterior layer. Significant reduction in CD was found in all three layers of cornea after 3 months in tIOL and after first month in PCRI groups, respectively.Cataract surgery alone reduces the CD. Reducing keratometric astigmatism

2019 Eye (London, England) Controlled trial quality: uncertain

33. Cornea verticillata in Fabry disease: a comparative study between slit-lamp examination and in vivo corneal confocal microscopy. (Abstract)

Cornea verticillata in Fabry disease: a comparative study between slit-lamp examination and in vivo corneal confocal microscopy. To compare the diagnostic power of slit-lamp examination with the in vivo corneal confocal microscopy (IVCM) as the gold standard in assessing the presence of corneal epithelial deposits in patients with Fabry disease (FD).Fourteen patients with FD (4 males, 10 females; mean age, 46.8 years) and eight healthy controls (4 males, 4 females; mean age, 36.75 years) were (...) included. All subjects underwent slit-lamp examination and IVCM of both central and peripheral corneal quadrants with the Heidelberg Retina Tomograph-III in combination with the Rostock Cornea Module.In patients with FD, 9 of 28 eyes (32%) showed the presence of cornea verticillata at the slit-lamp examination and 25 eyes (89%) showed the presence of epithelial hyper-reflective deposits at the IVCM. Of the 19 eyes negative at the slit-lamp examination, 16 eyes showed the presence of epithelial deposits

2019 British Journal of Ophthalmology

34. Corneal Cross-linking in Thin Corneas: 1-Year Results of Accelerated Contact Lens-Assisted Treatment of Keratoconus. (Abstract)

Corneal Cross-linking in Thin Corneas: 1-Year Results of Accelerated Contact Lens-Assisted Treatment of Keratoconus. To evaluate the safety and efficacy of accelerated contact lens-assisted cross-linking (A-CACXL) for patients with keratoconus and thin corneas.This retrospective study included consecutive patients undergoing A-CACXL for progressive keratoconus from 2015 to 2017. Patients with a minimum corneal thickness of 400 µm or less after epithelium removal who underwent A-CACXL (9 mW/cm2 (...) clinically significant stromal haze occurred in one case and completely resolved by 6 months. There was no significant change in endothelial cell density (P = .10).In patients with keratoconus and thin corneas, A-CACXL halted keratoconus progression in 80%, led to flattening in 45%, and significantly improved UDVA and keratometry values without any evidence of damage to the corneal endothelium or permanent adverse events. [J Refract Surg. 2019;35(10):642-648.].Copyright 2019, SLACK Incorporated.

2019 Journal of Refractive Surgery

35. Corneal abrasions

Corneal abrasions Corneal abrasions - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Corneal abrasions Last reviewed: February 2019 Last updated: March 2018 Summary Onset is usually sudden, and typical symptoms include a foreign body sensation (even if none present), photophobia, excessive tearing, blepharospasm, and blurry vision. Treatment involves adequate analgesia and topical antibiotics. Contact lens wearers (...) are at increased risk of Pseudomonas infection. Most abrasions heal within 1 or 2 days and have very few sequelae. Larger defects, or those associated with contact lens use, should have ophthalmological follow-up in 1 to 2 days to ensure healing. Complications are rare but include corneal ulceration and keratitis. Definition Corneal abrasions are corneal epithelial defects. They are common and are typically caused by mechanical trauma from external objects such as fingernails and branches, foreign bodies

2018 BMJ Best Practice

36. Correction: Paradox response of cornea to different color intensities of visible light: An experimental study. Full Text available with Trip Pro

Correction: Paradox response of cornea to different color intensities of visible light: An experimental study. [This corrects the article DOI: 10.1371/journal.pone.0196827.].

2019 PLoS ONE

37. CCR2+ migratory macrophages with M1 status are the early-responders in the cornea of HSV-1 infected mice. Full Text available with Trip Pro

CCR2+ migratory macrophages with M1 status are the early-responders in the cornea of HSV-1 infected mice. Complex interactions between HSV-1 and infiltrating immune cells play important roles in establishing localized, acute virus replication as well as chronic latent infection. The extent and duration of initial virus replication are the key determinants of subsequent pathologic inflammatory responses and therefore, the accumulation of immune cell populations at this time point is a key target (...) for prevention. Therefore, we evaluated the role of various immune cell infiltrates between 1 h and 28 days post-infection (PI) using mice infected with virulent HSV-1 strain McKrae without corneal scarification. The effect of corneal scarification on immune cell infiltrates was also determined. We first determined the activation status and origin of macrophage infiltrates as early as 1 h PI. We found a sharp increase in the total macrophage population after 12 h PI, that was primarily due to infiltration

2019 PLoS ONE

38. Comprehensive evaluation of total corneal refractive power by ray tracing in predicting corneal power in eyes after small incision lenticule extraction. Full Text available with Trip Pro

Comprehensive evaluation of total corneal refractive power by ray tracing in predicting corneal power in eyes after small incision lenticule extraction. To assess the prediction accuracy of four variations of total corneal refractive power (TCRP) by the ray tracing method in determining corneal power in eyes after myopic small incision lenticule extraction (SMILE).Forty eyes of forty patients who had undergone myopic SMILE were enrolled in this prospective study. Manifest refraction (...) to 0.96 D), respectively, while the modified 4.0 mm TCRPpupil,zone (TCRPpuil,zone + 0.70 D) and TCRPapex,zone (TCRPapex,zone+0.70 D) yielded the narrowest 95% LOA of (-0.96 to 0.95 D) and (-0.96D, 1.05 D).Total corneal refractive power using the ray tracing method could predict corrected corneal power derived from the CHM in eyes following SMILE surgery after simple modification.

2019 PLoS ONE

39. Changes in corneal thickness and corneal endothelial cell density after phacoemulsification cataract surgery: a double-blind randomized trial Full Text available with Trip Pro

Changes in corneal thickness and corneal endothelial cell density after phacoemulsification cataract surgery: a double-blind randomized trial Age-related cataract is a leading cause of visual impairment, considered a global health burden, it is responsible for over 47% of blindness worldwide. Surgical intervention is usually the treatment of choice and phacoemulsification cataract surgery with implantation of an intraocular lens is the most common procedure, which may have several (...) complications.To determine the effects of phacoemulsification surgery on corneal endothelial cell density and corneal thickness in patients undergoing cataract surgery.The present study was conducted on patients diagnosed with immature senile cataract requiring surgical intervention from November 2013 to 2014 in Khatam al Anbia Hospital (a tertiary ophthalmology center). Physical examination included best-corrected visual acuity using the Snellen chart, refraction, slit-lamp bio-microscopy for anterior chamber

2018 Electronic physician Controlled trial quality: uncertain

40. Case of progressive hyperopia due to flattening of cornea Full Text available with Trip Pro

examinations showed clear corneas but Descemet's folds and fine pigmentations and opacities were present beneath the corneal epithelium in both eyes. Analysis of the corneal shape by anterior segment optical coherence tomography showed that the corneas were flattened, and the corneal refractive power was decreased in both eyes. The large values of the higher-order aberration in the cornea and total eye displayed bilateral irregular astigmatism. She obtained good vision by wearing hard contact lenses (...) Case of progressive hyperopia due to flattening of cornea To report a case that had a progressive decrease in the visual acuity caused by a progressive increase in the hyperopia due to a flattening of the cornea.A 50-year-old woman complained of decreased vision in both eyes. Her decimal best-corrected visual acuity was 1.2 in the right and 0.5 in the left eyes, and the refractive error (spherical equivalent) was +3.75 diopters (D) for the right eye and +6.5 D for the left eye. Slit-lamp

2018 American journal of ophthalmology case reports

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