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81. Electronic Vapor Cigarette Battery Explosion Causing Shotgun-like Superficial Wounds and Contusion (PubMed)

Electronic Vapor Cigarette Battery Explosion Causing Shotgun-like Superficial Wounds and Contusion 26973744 2016 12 23 2018 11 13 1936-9018 17 2 2016 Mar The western journal of emergency medicine West J Emerg Med Electronic Vapor Cigarette Battery Explosion Causing Shotgun-like Superficial Wounds and Contusion. 177-80 10.5811/westjem.2016.1.29410 Shastry Siri S University of California Irvine Medical Center, Department of Emergency Medicine, Orange, California. Langdorf Mark I MI University (...) of California Irvine Medical Center, Department of Emergency Medicine, Orange, California. eng Case Reports Journal Article 2016 03 02 United States West J Emerg Med 101476450 1936-900X IM Adult Blast Injuries etiology Contusions diagnosis etiology Electric Power Supplies adverse effects Electronic Nicotine Delivery Systems adverse effects Explosions Humans Male 2015 12 02 2016 01 07 2016 01 13 2016 3 15 6 0 2016 3 15 6 0 2016 12 24 6 0 ppublish 26973744 10.5811/westjem.2016.1.29410 wjem-17-177 PMC4786238

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2016 Western Journal of Emergency Medicine

82. Assessment of Glial Scar, Tissue Sparing, Behavioral Recovery and Axonal Regeneration following Acute Transplantation of Genetically Modified Human Umbilical Cord Blood Cells in a Rat Model of Spinal Cord Contusion (PubMed)

Assessment of Glial Scar, Tissue Sparing, Behavioral Recovery and Axonal Regeneration following Acute Transplantation of Genetically Modified Human Umbilical Cord Blood Cells in a Rat Model of Spinal Cord Contusion This study investigated the potential for protective effects of human umbilical cord blood mononuclear cells (UCB-MCs) genetically modified with the VEGF and GNDF genes on contusion spinal cord injury (SCI) in rats. An adenoviral vector was constructed for targeted delivery of VEGF (...) and GDNF to UCB-MCs. Using a rat contusion SCI model we examined the efficacy of the construct on tissue sparing, glial scar severity, the extent of axonal regeneration, recovery of motor function, and analyzed the expression of the recombinant genes VEGF and GNDF in vitro and in vivo.Transplantation of UCB-MCs transduced with adenoviral vectors expressing VEGF and GDNF at the site of SCI induced tissue sparing, behavioral recovery and axonal regeneration comparing to the other constructs tested

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2016 PloS one

83. Comparison of Mechanical Allodynia and Recovery of Locomotion and Bladder Function by Different Parameters of Low Thoracic Spinal Contusion Injury in Rats (PubMed)

Comparison of Mechanical Allodynia and Recovery of Locomotion and Bladder Function by Different Parameters of Low Thoracic Spinal Contusion Injury in Rats The present study was designed to examine the functional recovery following spinal cord injury (SCI) by adjusting the parameters of impact force and dwell-time using the Infinite Horizon (IH) impactor device.Sprague-Dawley rats (225-240 g) were divided into eight injury groups based on force of injury (Kdyn) and dwell time (seconds

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2016 The Korean journal of pain

84. Frontal Lobe Contusion in Mice Chronically Impairs Prefrontal-Dependent Behavior (PubMed)

Frontal Lobe Contusion in Mice Chronically Impairs Prefrontal-Dependent Behavior Traumatic brain injury (TBI) is a major cause of chronic disability in the world. Moderate to severe TBI often results in damage to the frontal lobe region and leads to cognitive, emotional, and social behavioral sequelae that negatively affect quality of life. More specifically, TBI patients often develop persistent deficits in social behavior, anxiety, and executive functions such as attention, mental flexibility (...) , and task switching. These deficits are intrinsically associated with prefrontal cortex (PFC) functionality. Currently, there is a lack of analogous, behaviorally characterized TBI models for investigating frontal lobe injuries despite the prevalence of focal contusions to the frontal lobe in TBI patients. We used the controlled cortical impact (CCI) model in mice to generate a frontal lobe contusion and studied behavioral changes associated with PFC function. We found that unilateral frontal lobe

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2016 PloS one

85. Senegenin inhibits neuronal apoptosis after spinal cord contusion injury (PubMed)

Senegenin inhibits neuronal apoptosis after spinal cord contusion injury Senegenin has been shown to inhibit neuronal apoptosis, thereby exerting a neuroprotective effect. In the present study, we established a rat model of spinal cord contusion injury using the modified Allen's method. Three hours after injury, senegenin (30 mg/g) was injected into the tail vein for 3 consecutive days. Senegenin reduced the size of syringomyelic cavities, and it substantially reduced the number of apoptotic

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2016 Neural Regeneration Research

86. 18F-FDG-PET imaging of rat spinal cord demonstrates altered glucose uptake acutely after contusion injury (PubMed)

18F-FDG-PET imaging of rat spinal cord demonstrates altered glucose uptake acutely after contusion injury Spinal cord injury (SCI) results in an acute reduction in neuronal and glial cell viability, disruption in axonal tract integrity, and prolonged increases in glial activity and inflammation, all of which can influence regional metabolism and glucose utilization. To date, the understanding of glucose uptake and utilization in the injured spinal cord is limited. Positron emission tomography (...) (PET)-based measurements of glucose uptake may therefore serve as a novel biomarker for SCI. This study aimed to determine the acute and sub-acute glucose uptake pattern after SCI to determine its potential as a novel non-invasive tool for injury assessment and to begin to understand the glucose uptake pattern following acute SCI. Briefly, adult male Sprague-Dawley rats were subjected to moderate contusion SCI, confirmed by locomotor function and histology. PET imaging with [(18)F

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2016 Neuroscience letters

87. Diagnosing Myocardial Contusion after Blunt Chest Trauma (PubMed)

Diagnosing Myocardial Contusion after Blunt Chest Trauma A myocardial contusion refers to a bruise of the cardiac muscle, the severity of which can vary depending on the severity of the injury and when the injury occurs. It is a major cause of rapid death which happens after blunt chest trauma and should be suspected at triage in the emergency department. We demonstrated that suspected myocardial contusion patients who have normal electrocardiograms (ECGs) and biomarker tests can be safely (...) discharged. However, if the test results are abnormal, the next steps should be echocardiography and more advanced measures. Diagnosing myocardial contusion is very difficult because of its nonspecific symptoms. If a myocardial contusion happens, cardiogenic shock or arrhythmia must be anticipated, and the patient must be carefully monitored.

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2016 The Journal of Tehran University Heart Center

88. Quadriceps Contusion

Quadriceps Contusion Quadriceps Contusion Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Quadriceps Contusion Quadriceps Contusion (...) Aka: Quadriceps Contusion , Thigh Contusion From Related Chapters II. Mechanism Direct blow to thigh III. Signs: Limited knee flexion (Assess at 12 to 24 hour) Mild Injury flexion >90 degrees Moderate flexion 45-90 degrees Severe flexion <45 degrees IV. Management Phase 1: Wrap knee, extended to 130 degrees Phase 2: Range of Motion Phase 3: Return to Play Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Quadriceps Contusion

2018 FP Notebook

89. Myocardial Contusion

Myocardial Contusion Myocardial Contusion Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Myocardial Contusion Myocardial Contusion (...) Aka: Myocardial Contusion From Related Chapters II. Causes Chest III. History Bent stearing wheel in a IV. Signs Anterior chest wall injury signs Sternal tenderness Sternal deformity V. Labs Serial levels Serum myoglobin Serum VI. Diagnostics Telemetry monitoring Serial Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Myocardial Contusion." Click on the image (or right click) to open the source website in a new browser window

2018 FP Notebook

90. Cardiac Contusion

Cardiac Contusion Cardiac Contusion Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Cardiac Contusion Cardiac Contusion Aka: Cardiac (...) Contusion , Blunt Cardiac Injury , Blunt Myocardial Injury , Myocardial Contusion , Heart Contusion From Related Chapters II. Causes High speed injury (e.g. MVA) III. See Also IV. Symptoms V. Signs VI. Labs Increased in Cardiac Contusion VII. Diagnostics (EKG) See s (PVC) Unexplained ST Segment changes may occur in blunt cardiac Advanced hemodynamic monitoring (if central access) increased VIII. Imaging Wall motion abnormality IX. Differential Diagnosis See See associated conditions below X. Associated

2018 FP Notebook

91. Brain Contusion

Brain Contusion Brain Contusion Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Brain Contusion Brain Contusion Aka: Brain Contusion (...) From Related Chapters II. Pathophysiology III. Signs ral Focal neurologic deficits Prolonged coma Decerebrate rigidity Unequal dilated pupils IV. Imaging (at presention and repeated in 12 hours) Cerebral Necrosis Intraparenchymal V. Management Emergent Neurosurgical Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Brain Contusion." Click on the image (or right click) to open the source website in a new browser window. Related

2018 FP Notebook

92. Contusion

Contusion Contusion Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Contusion Contusion Aka: Contusion , Bruise , Soft Tissue Hematoma (...) , Subcutaneous Hematoma , Subepidermal Hemorrhage , Bruising II. Pathophysiology Blunt injury disrupts soft tissue (skin, muscle) capillaries and venules, resulting in into local interstitial tissue III. Risk Factors (e.g. Ehlers-Danlos Syndrome) s IV. Exam Do not blanch on pressure Contrast with a ( , ) which does blanch Compare with or which like a Contusion does not blanch Color (unreliable as an indicator of injury timing) Days 0-2: Swelling and tenderness Days 2-5: Red, blue or purple coloration Days 5

2018 FP Notebook

93. Pulmonary Contusion

Pulmonary Contusion Pulmonary Contusion Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Pulmonary Contusion Pulmonary Contusion Aka (...) : Pulmonary Contusion , Lung Contusion , Chest Contusion From Related Chapters II. Epidemiology Pulmonary Contusion is the most common potentially lethal III. Risk Factors: Increased Morbidity ( ) IV. Pathophysiology to chest results in Lung Contusion May occur without Slow, insidious may ensue resulting in V. Indications: Early Intubation with <65 mmHg or <90% VI. Management: Disposition Admit most patients (especially elderly) Respiratory status can deteriorate rapidly Discharge indications Young

2018 FP Notebook

94. Cardiac Contusion

Cardiac Contusion Cardiac Contusion Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Cardiac Contusion Cardiac Contusion Aka: Cardiac (...) Contusion , Blunt Cardiac Injury , Blunt Myocardial Injury , Myocardial Contusion , Heart Contusion From Related Chapters II. Causes High speed injury (e.g. MVA) III. See Also IV. Symptoms V. Signs VI. Labs Increased in Cardiac Contusion VII. Diagnostics (EKG) See s (PVC) Unexplained ST Segment changes may occur in blunt cardiac Advanced hemodynamic monitoring (if central access) increased VIII. Imaging Wall motion abnormality IX. Differential Diagnosis See See associated conditions below X. Associated

2018 FP Notebook

95. ECG of pneumopericardium and probable myocardial contusion shows typical pericarditis

ECG of pneumopericardium and probable myocardial contusion shows typical pericarditis Dr. Smith's ECG Blog: ECG of pneumopericardium and probable myocardial contusion shows typical pericarditis Wednesday, December 9, 2015 A young man was in a rollover Motor Vehicle Collision, with a chest laceration and chest pain. He underwent a CT scan of the chest: There is a very small pneumothorax anterior to the heart This image is from slightly lower down: There is a bit of air in the pericardium (...) A troponin returned elevated, so this ECG was recorded: There is some minimal ST elevation in inferior and lateral leads. This is consistent with percarditis. The troponin shows that there is some myocardial damage. Is it myocardial contusion, or myo-pericarditis? Or pericarditis as a result of myocardial contusion? 6 hours later: There is diffuse ST elevation without large T-waves (low T-wave to ST segment ratio, which is typical of pericarditis vs. STEMI). There is PR depression. There is also

2015 Dr Smith's ECG Blog

96. Comparison of spinal cord contusion and transection: functional and histological changes in the rat urinary bladder. (PubMed)

Comparison of spinal cord contusion and transection: functional and histological changes in the rat urinary bladder. To compare the effect of complete transection (tSCI) and contusion spinal cord injury (cSCI) on bladder function and bladder wall structure in rats.A total of 30 female Sprague-Dawley rats were randomly divided into three equal groups: an uninjured control, a cSCI and a tSCI group. The cSCI group underwent spinal cord contusion, while the tSCI group underwent complete spinal cord (...) and contusion produce different bladder phenotypes in rat models of SCI. Functional data suggest that the tSCI group has an obstructive high-pressure voiding pattern, while the cSCI group has more uninhibited detrusor contractions.© 2016 The Authors BJU International © 2016 BJU International Published by John Wiley & Sons Ltd.

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2016 BJU international

97. Diaphragm electromyographic activity following unilateral midcervical contusion injury in rats (PubMed)

Diaphragm electromyographic activity following unilateral midcervical contusion injury in rats Contusion-type injuries to the spinal cord are characterized by tissue loss and disruption of spinal pathways. Midcervical spinal cord injuries impair the function of respiratory muscles and may contribute to significant respiratory complications. This study systematically assessed the impact of a 100-kDy unilateral C4 contusion injury on diaphragm muscle activity across a range of motor behaviors (...) in neural drive (RMS value at 75 ms after the onset of diaphragm activity) and was more pronounced during higher force, nonventilatory motor behaviors. Animals in the contusion group displayed a transient decrease in respiratory rate and an increase in burst duration at 1 DPI. By 7 days, following midcervical contusion, there was significant perineuronal net formation and white-matter loss that spanned 1 mm around the injury epicenter. Taken together, these findings are consistent with increased

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2016 Journal of neurophysiology

98. CT-negative, MRI GRE-positive primary motor cortex contusion causing isolated foot drop (PubMed)

CT-negative, MRI GRE-positive primary motor cortex contusion causing isolated foot drop Isolated acute foot drop due to traumatic brain injury is exceedingly rare and is often misdiagnosed during initial evaluation. Here, we present the case of a patient who presented with left foot drop after falling off a bicycle.The patient is a 55-year-old male who was mountain biking when he fell, hit his head, and lost consciousness. Neurologic examination of the left leg revealed foot drop, no sensory

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2016 Surgical neurology international

99. Paraplegia caused by cerebral contusions in the bilateral precentral gyri (PubMed)

Paraplegia caused by cerebral contusions in the bilateral precentral gyri Paraplegia is mainly caused by spinal cord disease and rarely occurs due to head trauma. In this report, we describe a case of paraplegia caused by cerebral contusions in the bilateral precentral gyri.A 72-year-old man was admitted to our hospital with mildly impaired consciousness and severe pure motor paralysis in both legs. He was healthy until the morning of the day, but his wife found him injured in front of his (...) house upon returning home. He had a subcutaneous hematoma in his occipital region, and seemed to have slipped by accident. Computed tomography of the brain and magnetic resonance imaging (MRI) of his spinal cord revealed no apparent cause of the paraplegia, although an MRI of his brain clearly revealed cerebral contusions in the bilateral precentral gyri. The cerebral contusion was diagnosed as the cause of pure motor paralysis of lower extremities. He received rehabilitation, and manual muscle

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2016 Surgical neurology international

100. Time-dependent gene expression analysis after mouse skeletal muscle contusion (PubMed)

Time-dependent gene expression analysis after mouse skeletal muscle contusion Though the mechanisms of skeletal muscle regeneration are deeply understood, those involved in muscle contusion, one of the most common muscle injuries in sports medicine clinics, are not. The objective of this study is to explore the mechanisms involved in muscle regeneration after contusion injury.In this study, a total of 72 mice were used. Eight of them were randomly chosen for the control group, while the rest (...) were subjected to muscle contusion. Subsequently, their gastrocnemius muscles were harvested at different time points. The changes in muscle morphology were assessed by hematoxylin and eosin (HE) stain. In addition, the gene expression was analyzed by real-time polymerase chain reaction.The data showed that the expression of many genes, i.e., specific markers of immune cells and satellite cells, regulatory factors for muscle regeneration, cytokines, and chemokines, increased in the early stages

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2016 Journal of sport and health science

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