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9141. Childhood head injury and expression of schizophrenia in multiply affected families. Full Text available with Trip Pro

with a history of childhood head injury had a significantly younger median age at onset of psychosis (20 years) compared with those with no such history (25 years; z = -2.98; P =.003). The severity of head injury ranged from minimal to mild, including concussions, but within this narrow range, severity was correlated with younger age at onset (r(s) = -0.66; P =.005). Head injury occurred a median of 12 years before the onset of psychosis. Results were similar if head injuries during adolescence were included

2003 Archives of General Psychiatry

9142. Inhaled corticosteroids in the long-term management of patients with chronic obstructive pulmonary disease. (Abstract)

, on the other hand, leads to increased symptoms and elevates the risk of exacerbations by 50% above baseline levels. Patients' health-related quality of life is also improved by the use of inhaled corticosteroids. It is clear that inhaled corticosteroids elevate the risk of thrush, dysphonia and skin bruising by 2-fold compared with placebo. In addition, the sum of evidence suggests a modest deleterious effect for inhaled corticosteroids on bone mineral density, especially for formulations that have

2003 Drugs & Aging

9143. From the roots of rhinology: the reconstruction of nasal injuries by Hippocrates. (Abstract)

that Hippocrates classified nasal injuries, from simple contusions of soft tissues to complicated fractures. Hippocrates provided detailed instructions for each case, from poultice application and bandaging to reconstruction and reshaping of the nasal bones in cases of fractures and deviation. Hippocrates' texts reflect the interest of the classical period in nasal injuries, a common enough accident in athletics. Hippocratic conservative and surgical management for each form of injury was adopted by later

2003 Rhinology and Laryngology

9144. Morbidity from rib fractures increases after age 45. (Abstract)

criteria. Based on an analysis of increasing age, number of rib fractures, and adverse outcomes variables, patients were separated into four groups: group 1, 15 to 44 years old with 1 to 4 rib fractures; group 2, 15 to 44 years old with more than 4 rib fractures; group 3, 45 years or older with 1 to 4 rib fractures; and group 4, 45 years or more with more than 4 rib fractures. The four groups had similar numbers of pulmonary contusions (30%) and incidence of hemopneumothorax (51%). Ventilator days (5.8

2003 Journal of the American College of Surgeons

9145. Thrombotic thrombocytopenic purpura and human immunodeficiency virus complicating pregnancy. (Abstract)

-positive patient complained of easy bruising, hematuria, fever, myalgias, and headache during the second trimester of pregnancy. Laboratory testing revealed hemolytic anemia and severe thrombocytopenia. Bone marrow biopsy was consistent with thrombocytopenic purpura. The patient recovered after plasmapheresis. At 36 weeks' gestation, she was delivered for preeclampsia and fetal growth restriction.Absence of the classic pentad seen in thrombocytopenic purpura among pregnant HIV-positive patients may

2002 Obstetrics and Gynecology

9146. Current treatment of gunshot wounds to the spine. (Abstract)

Current treatment of gunshot wounds to the spine. The incidence of spinal cord injury from gunshot wounds in penetrating trauma continues to increase with the violent nature of society. This particularly is true in urban areas, as is found with other violent crime. Either the direct path of the bullet or the concussive effects cause injury to the spine and spinal column. Thorough patient evaluation and appropriate radiographic studies will provide the keys to treatment of these patients

2003 Clinical Orthopaedics and Related Research

9147. Ice reduces edema. A study of microvascular permeability in rats. (Abstract)

Ice reduces edema. A study of microvascular permeability in rats. Ice is applied following a soft-tissue injury on the basis of clinical information. This study investigates the relationship between ice therapy (cryotherapy) and edema by determining microvascular permeability before and after contusion with and without ice therapy and provides data supporting a reduction in edema following cryotherapy.A dorsal microvascular chamber was created in rats to allow the direct examination (...) of microvascular parameters in intact, pre-established microvascular beds of the cutaneous maximus muscle in conscious rats. The rats received a contusion or sham contusion and were treated with cryotherapy or were not treated. Microvascular permeability (edema) was assessed by measuring fluorescent-labeled albumin in the interstitial fluid before and after contusion.Microvascular permeability following contusion was significantly increased in the group that received the contusion without cryotherapy compared

2002 The Journal of Bone and Joint Surgery. American Volume

9148. Do motor vehicle airbags increase risk of ocular injuries in adults? (Abstract)

and AB cohorts were mild (eyebrow laceration, lid contusion, bruising). The risk of airbag-related eye injury was 2.5% for any eye injury and 0.4% for severe eye injury. In single accidents when seat belts were used, the risks were 2.0% and 0.5%, respectively. In the accidents from the FAS data no difference was observed in the risk for eye injury between survivors in incidents involving airbag deployment and incidents not involving airbags. This risk was not found to be greater among eyeglass

2003 Ophthalmology

9149. Spontaneous closure of traumatic macular hole. (Abstract)

. OCT showed macular hole enlargement and worsening of the macular edema during follow up. The macular hole finally closed 4 months after injury. Case 3 was a 15-year-old boy. He had a tiny rough-edged macular hole at his first consultation with a local ophthalmologist. The macular hole finally closed 6 months after injury.Macular hole can be a result of severe damage from ocular concussion or damage to the retina. For 6 months following injury, traumatic macular hole should probably be observed

2002 American Journal of Ophthalmology

9150. Correlation between retinal abnormalities and intracranial abnormalities in the shaken baby syndrome. (Abstract)

survey. In this retrospective review, ophthalmoscopic and intracranial abnormalities were correlated.The age of patients ranged from 2 to 48 months (mean - SD, 10.6 +/- 10.4 months). Neuroimaging was abnormal in all 75 cases. Findings included subdural hematoma (70 children, 93%), cerebral edema (33 children, 44%), subarachnoid hemorrhage (12 children, 16%), vascular infarction (nine children, 12%), intraparenchymal blood (six children, 8%), parenchymal contusion (six children, 8%), and epidural

2002 American Journal of Ophthalmology

9151. Epidemiology of posttraumatic epilepsy: a critical review. (Abstract)

for the development of seizures in the first week after injury include acute intracerebral hematoma (especially subdural hematoma), younger age, increased injury severity, and chronic alcoholism. Significant risk factors for the development of seizures >1 week after TBI include seizures within the first week, acute intra-cerebral hematoma (especially subdural hematoma), brain contusion, increased injury severity, and age >65 years at the time of injury.Epilepsy is a frequent consequence of brain injury in both

2003 Epilepsia

9152. Grisel's syndrome: a case of potentially lethal spinal cord injury in the adult. (Abstract)

Grisel's syndrome: a case of potentially lethal spinal cord injury in the adult. A 22-year-old woman presented with respiratory difficulty and quadriparesis two weeks after an upper respiratory tract infection. CT showed mild (Type I) rotatory atiantoaxial subluxation, but MRI demonstrated a severely contused and oedematous spinal cord at C2-3. The case was managed conservatively with collar, steroid and antibiotics. The outcome was excellent.

2002 British Journal of Neurosurgery

9153. Comparison of external dacryocystorhinostomy with nonlaser endonasal dacryocystorhinostomy. (Abstract)

these outcomes with a two-sample test for equality of proportions with continuity correction (P = 0.914, power = 80% for alpha = 0.05 to detect a decreased success rate of 12%). Eleven of the failed cases in each group underwent revision EN-DCR surgery, with 90.9% success in each group. Epistaxis requiring perioperative nasal packing occurred in 7 (4.6%) EX-DCR patients and 11 (5.5%) EN-DCR patients. Wound complications in EX-DCR included bruising in four patients, localized infections in two patients

2003 Ophthalmology

9154. Impact of early intervention on outcome following mild head injury in adults. Full Text available with Trip Pro

group and were assessed one week and three months after injury; 123 were assigned to a non-intervention control group and were seen at three months only. Participants completed measures of preinjury psychological adjustment, concurrent life stresses, post-concussion symptoms, and tests of attention, speed of information processing, and memory. Subjects seen at one week were given an information booklet outlining the symptoms associated with mild head injury and suggested coping strategies. Those

2002 Neurosurgery and Psychiatry

9155. Intraventricular monitoring for temporal lobe epilepsy: report on technique and initial results in eight patients. Full Text available with Trip Pro

horn to the temporal tip. The endoscope was removed and electrode placement was confirmed through an intraoperative lateral skull radiograph and on visual inspection at the time of resection in two cases.The IVE was crucial for localisation in one patient and helped localisation in four others. Surgery was offered to seven patients. The only serious complication of IVE placement was a thalamic contusion presumably from an errant electrode tip. One electrode was inadvertently placed into the frontal

2003 Neurosurgery and Psychiatry

9156. Cognitive dysfunction in young men following head injury in childhood and adolescence: a population study. Full Text available with Trip Pro

or shortly thereafter: 970 had suffered a single concussion and were in hospital for one day only; 521 had two concussions at separate times and were in hospital for one day only on each occasion; 961 had a cranial fracture; and 639 had a cerebral lesion. For all of these, scores on the draft board's cognitive screening test were obtained, dichotomised as dysfunctional or non-dysfunctional. Prevalences of dysfunctional scores were compared with population base rates (about 20% of all Danish men appearing (...) before the draft board had a score classified as dysfunctional).For young men who had suffered a single concussion, cranial fracture, or cerebral lesion before 12 years of age, resulting in less than 12 days of hospital admission (n = 376), rates of cognitive dysfunction did not exceed those in the general population (odds ratios < 1.4, NS), but the odds ratios became significant and > 1.4 where the injury occurred after age 11. For those with a cerebral lesion resulting in over 11 days of hospital

2003 Neurosurgery and Psychiatry

9157. Metronomic therapy with cyclophosphamide and dexamethasone for prostate carcinoma. (Abstract)

while receiving treatment. The duration of response was 8 months (95% confidence interval [95% CI], 4-10 months). The duration of treatment was 9 months (95% CI, 6-14 months). The treatment was reported to be well tolerated with side effects being primarily bruising, Cushingoid facies, and gastrointestinal distress.In the current study, low-dose dexamethasone and cyclophosphamide demonstrated efficacy as salvage therapy in the treatment of patients with hormone-refractory prostate

2003 Cancer

9158. Cutaneous angiosarcoma of the scalp: a multidisciplinary approach. Full Text available with Trip Pro

with a median age of 71.0 years. Most patients presented after a delay in diagnosis with either a bruise-like macule (48.3%) or a nonbruise-like nodule (51.7%). Seventy-five percent of patients had pathologic Stage T2 disease, and 76% of patients had high-grade tumors. Virtually all patients underwent surgical excision (96.6%); however, negative surgical margins were achieved in only 21.4% of patients. Multiple lesions on presentation were associated with a shorter time to recurrence (P = 0.02). The median

2003 Cancer

9159. Ventilation by the Open Lung Concept in spite of traumatic lung herniation. (Abstract)

Ventilation by the Open Lung Concept in spite of traumatic lung herniation. Traumatic herniation of the lung is uncommon. We report a patient suffering from multiple injuries including severe pulmonary contusion and traumatic parasternal lung herniation, who developed acute respiratory distress syndrome. In spite of the lung herniation, we used mechanical ventilation according to the Open Lung Concept. Oxygenation improved rapidly, and early operative stabilization was possible.

2003 British Journal of Anaesthesia

9160. Risk assessment of hemorrhagic complications associated with nonsteroidal antiinflammatory medications in ambulatory pain clinic patients undergoing epidural steroid injection. (Abstract)

Risk assessment of hemorrhagic complications associated with nonsteroidal antiinflammatory medications in ambulatory pain clinic patients undergoing epidural steroid injection. We prospectively studied 1035 individuals undergoing 1214 epidural steroid injections to determine the risk of hemorrhagic complications. A history of bruising or bleeding was present in 176 (15%) patients. A platelet count was assessed in 77 patients before the epidural steroid injection; none was less than 100 x 10(9

2002 Anesthesia and Analgesia

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