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Contraction Stress Test

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101. Suppression of endoplasmic reticulum stress improves endothelium-dependent contractile responses in aorta of the spontaneously hypertensive rat Full Text available with Trip Pro

)) mediated by extracellular signal-regulated kinase (ERK1/2) and cyclooxygenase (COX) activations. Although endoplasmic reticulum (ER) stress has been shown to contribute to pathophysiological alterations in cardiovascular diseases, the relationship between ER stress and EDCF-mediated responses remains unclear. We tested the hypothesis that ER stress plays a role in EDCF-mediated responses via activation of the cPLA2/COX pathway in the aorta of the spontaneously hypertensive rat (SHR). Male SHR (...) and Wistar-Kyoto rats (WKY) were treated with ER stress inhibitor, tauroursodeoxycholic acid or 4-phenlybutyric acid (TUDCA or PBA, respectively, 100 mg·kg(-1)·day(-1) ip) or PBS (control, 300 μl/day ip) for 1 wk. There was a decrease in systolic blood pressure in SHR treated with TUDCA or PBA compared with control SHR (176 ± 3 or 181 ± 5, respectively vs. 200 ± 2 mmHg). In the SHR, treatment with TUDCA or PBA normalized aortic (vs. control SHR) 1) contractions to acetylcholine (ACh), AA, and tert-butyl

2013 American Journal of Physiology - Heart and Circulatory Physiology

102. Epigallocatechin-3-Gallate Reduces Myometrial Infiltration, Uterine Hyperactivity, and Stress Levels and Alleviates Generalized Hyperalgesia in Mice Induced With Adenomyosis Full Text available with Trip Pro

Epigallocatechin-3-Gallate Reduces Myometrial Infiltration, Uterine Hyperactivity, and Stress Levels and Alleviates Generalized Hyperalgesia in Mice Induced With Adenomyosis In an effort to search for novel therapeutics for adenomyosis, we sought to determine whether treatment with epigallocatechin-3-gallate (EGCG) would suppress the myometrial infiltration, improve pain behavior, lower stress level, and reduce uterine contractility in a mice model of adenomyosis. Adenomyosis was induced in 28 (...) female ICR mice neonatally dosed with tamoxifen, while another 12 (group C) were dosed with solvent only, which served as a blank control. Starting from 4 weeks after birth, hot plate test was administrated to all mice every 4 weeks. At the 16th week, all mice induced with adenomyosis were randomly divided into 3 groups: low-dose EGCG (5 mg/kg), high-dose EGCG (50 mg/kg), and untreated. Group C received no treatment. After 3 weeks of treatment, the hot plate test was administered again, a blood

2013 Reproductive Sciences

103. The Efficacy of Electroacupuncture for Treatment of Simple Female Stress Urinary Incontinence: Comparison With Pelvic Floor Muscle Training-a Multicenter Randomized Controlled Trial

for Simple female stress urinary incontinence [ Time Frame: the 8, 20, 32 week ] Compare the difference of uase of specialty therapy for Simple female stress urinary incontinence between the 2 groups during the 1-8 weeks, 9-20 weeks and 21-32 weeks. Subgroup analysis: amount of leakage with 1h pad test as a measure of curative effect of electroacupuncture for different extent of simple female stress urinary incontinence. [ Time Frame: the 8, 20, 32 week ] The 8th week: difference of 1 h pad test (...) for simple female stress urinary incontinence, compared with the baseline; the 20th and 32th weeks: difference of 1h pad test for simple female stress urinary incontinence, compared with the baseline. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study

2013 Clinical Trials

104. Pelvic floor muscle training in women with stress urinary incontinence causes hypertrophy of the urethral sphincters and reduces bladder neck mobility during coughing. Full Text available with Trip Pro

which they learned how to properly contract their pelvic floor muscles (PFMs) and a home exercise program was prescribed, reviewed, and progressed; the control group received no treatment. Before and after the 12-week study period, ultrasound imaging was used to evaluate bladder neck position and mobility during coughing and Valsalva maneuver in supine and in standing, as well as urethral morphology. Secondary outcome measures included a 3-day bladder diary, 30-min pad test, the Incontinence Impact (...) Pelvic floor muscle training in women with stress urinary incontinence causes hypertrophy of the urethral sphincters and reduces bladder neck mobility during coughing. The purpose of this study was to determine the effect of a 12-week pelvic floor muscle (PFM) training program on urethral morphology and mobility in women with stress urinary incontinence (SUI).Forty women with SUI were randomly assigned to one of two groups: the treatment group received 12 weekly physiotherapy sessions during

2013 Neurourology and urodynamics Controlled trial quality: uncertain

105. Cerebral Blood Flow and PETCO2 on Neuromuscular Function During Environmental Stress

-wave) will be calculated. The amplitude of the H-reflex will be quantified in milllivolts. Maximal Voluntary Contraction [ Time Frame: Change from baseline 90-minutes ] During maximal voluntary contraction (MVC) testing, the participants' right arm will be secured in a custom made device used to isolate forearm flexion and to measure force production by the flexor carpi radialis muscle. Participants will be asked to produce a 5-second MVC and will be verbally encouraged to maintain maximal force (...) Cerebral Blood Flow and PETCO2 on Neuromuscular Function During Environmental Stress Cerebral Blood Flow and PETCO2 on Neuromuscular Function During Environmental Stress - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2013 Clinical Trials

106. The Influence of Cerebral Blood Flow and PETCO2 on Neuromuscular Function During Passive Heat Stress

: Change from baseline 90-minutes ] During maximal voluntary contraction (MVC) testing, the participants' right arm will be secured in a custom made device used to isolate forearm flexion and to measure force production by the flexor carpi radialis muscle. Participants will be asked to produce a 5-second MVC and will be verbally encouraged to maintain maximal force production throughout the duration of the contraction. MVC will be quantified as the maximum force production in newton meters. H-Reflex (...) The Influence of Cerebral Blood Flow and PETCO2 on Neuromuscular Function During Passive Heat Stress The Influence of Cerebral Blood Flow and PETCO2 on Neuromuscular Function During Passive Heat Stress - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2013 Clinical Trials

107. A Comparison of Electrical Pudendal Nerve Stimulation and Pelvic Floor Muscle Training for Female Stress Incontinence

) is used for TES Outcome Measures Go to Primary Outcome Measures : Stress test [ Time Frame: 12 weeks ] Secondary Outcome Measures : A questionnaire to measure the severity of symptoms and the quality of life in SUI women [ Time Frame: 12 weeks ] Other Outcome Measures: Pad test [ Time Frame: 12 weeks ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends (...) about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 25 Years to 85 Years (Adult, Older Adult) Sexes Eligible for Study: Female Accepts Healthy Volunteers: No Criteria Inclusion Criteria: SUI history Positive stress test result Urodynamically confirmed SUI Postvoid residual urine volume <50ml Exclusion

2013 Clinical Trials

108. Neurotech Vital Device For The Treatment Of Stress Urinary Incontinence

and at 6 months for main and cohort part of the study ] pelvic floor muscle function measured using sonographic/real time ultrasound imaging/recording with displacement measurement using on screen callipers on the sonogram unit to assess volitional contractions participants taking part in a 1 minute stress test [ Time Frame: We will compare the urine loss against the urine loss after 4weeks treatment with the device and also after 8weeks treatment with the device and 12 weeks treatment ] We will look (...) electrodes (large sticky black pads) which causes the pelvic floor to contract and relax, without you having to do anything. This treatment is not painful and is very similar to the workout you would get from relaxing and contracting your pelvic floor muscles yourself, however the device produces a much stronger contraction. The study is open to females who have failed a 6 week exercise programme and have been diagnosed with Stress Urinary Incontinence. It will take place at hospital uro-gynaecology

2013 Clinical Trials

109. The relevance of socio-demographic and occupational variables for the assessment of work-related stress risk. Full Text available with Trip Pro

Executive Management Standards Indicator Tool was used in a large survey to examine the relationship between work-related stress risks and workers' demographic and occupational characteristics. Out of 8,527 questionnaires distributed among workers (from 75 organizations) 6,378 were returned compiled (74.8%); a set of mixed effects models were adopted to test single and combined effects of the variables on work-related stress risk.Female workers reported lower scores on control and peer support and more (...) factors for work-related stress (except for role), the latter having more negative effects, increasing with age.The findings suggest that the assessment and management of work-related stress risk should consider specific socio-demographic and occupational risk factors such as gender, age, educational level, job status, shift work, commuting time, job contracts.

2013 BMC Public Health

110. Preoperative Testing

, urinalysis, or cardiac stress testing. [ , ] Advancing age, especially older than 70 years, is associated with increased hospital stay and perioperative morbidity and mortality. However, most people in this age group have comorbid conditions, and it remains unclear if perioperative complications are secondary to comorbid conditions or age itself (see also the article ). Contrary to a common belief, obesity does not increase postoperative complications. In a prospective cohort of 6336 patients undergoing (...) Preoperative Testing Preoperative Testing: Overview, Selective Workup, Summary Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjg1MTkxLW92ZXJ2aWV3 processing > Preoperative Testing Updated: Sep 16, 2015 Author

2014 eMedicine.com

111. Flu Tests

diagnose their current patient. He may also order a flu test along with other viral studies, such as RSV (respiratory syncytial virus - a virus that often infects young children and the elderly), or with bacterial tests, such as a streptococcus test (to check for group A streptococcus, the bacteria that cause a sore throat) if the cause of the infection is unclear. In rare instances, someone will contract influenza outside of the normal flu season. (This may happen when someone travels outside (...) Flu Tests Influenza Test Produced by In partnership with User Top Links Menu Search User Top Links Search Influenza (Flu) Tests Also Known As Flu PCR Rapid flu test Flu antigen test Flu subtyping Formal Name Influenza nucleic acid amplification test; Influenza polymerase chain reaction; Rapid influenza antigen test; Influenza point of care test; Influenza A and B culture; influenza direct immunofluorescence test; Influenza A subtype-specific PCR This article was last reviewed on 19 January 2015

2012 Lab Tests Online UK

112. Fetal Copeptin After Oxytocin Challenge Test

of uterine contractions on fetal copeptin levels in umbilical cord blood is studied. Condition or disease Pregnancy Detailed Description: Background: Vaginal delivery evokes a dramatic surge in stress hormones facilitating the transition of the infant to extra-uterine life. Infants born by elective cesarean section (C-section) are known to have a higher risk for compromised birth adaptation. Labor is vital for vaginal delivery and triggers fetal stress hormone release. Fetal plasma copeptin, a surrogate (...) marker of arginine vasopressin, has been found to be 100 to 1000-fold increased after vaginal delivery as compared to elective C-section. However, the relationship of labor intensity and fetal stress hormone release is largely unknown. Objective: The purpose of this study is to determine fetal copeptin in newborns delivered by C-section to mothers who had an oxytocin challenge test (OCT) just prior to birth as compared to those without OCT. Protocol: Pregnant women at term are eligible to participate

2013 Clinical Trials

113. Small left atrial volume is an independent predictor for fainting during head-up tilt test: the impact of intracardiac volume reserve in vasovagal syncope. (Abstract)

Small left atrial volume is an independent predictor for fainting during head-up tilt test: the impact of intracardiac volume reserve in vasovagal syncope. Vigorous left ventricular (LV) contraction with progressive ventricular emptying during orthostatic stress may induce hyper-responsiveness of cardiac mechanoreceptor and vasovagal syncope (VVS). We hypothesized that intracardiac volume reserve estimated by the left atrial (LA) volume index (LAVI) plays an important role in the mechanism (...) of VVS.A total of 234 patients (115 male, 44 ± 18 years) who underwent head-up tilt test (HTT) and transthoracic echocardiography for unexplained syncope were consecutively enrolled. Patients with a positive HTT result (HTT+; n=152) were compared with those with negative HTT response (HTT-; n=82).1. Compared to HTT- patients, HTT+ patients were younger (41 ± 17 vs. 48 ± 17 years, p=0.005), included a higher number of females (56% vs. 50%, p=0.009) and showed higher basal heart rate (67 ± 12 vs. 63 ± 11

2013 International journal of cardiology

114. [Effect the adding of biofeedback to the training of the pelvic floor muscles to treatment of stress urinary incontinence]. (Abstract)

[Effect the adding of biofeedback to the training of the pelvic floor muscles to treatment of stress urinary incontinence]. To investigate the effect of adding biofeedback (BF) to the training of pelvic floor muscles (PFMT) for the treatment of stress urinary incontinence (SUI).A prospective pilot study, randomized and controlled with women with SUI without sphincter deficiency, detected by urodynamic study and who performed the correct PFM contraction. Women with neuromuscular disorders (...) and grade III and IV genital prolapse were excluded. Forty women were randomized into a CONTROL GROUP and BF Group. The PFMT protocol with BF equipment consisted of three sets of ten slow contractions (tonic), with a holding time of six to eight seconds at each contraction followed by a rest period of equal duration. After each sustained contraction, they performed three to four fast contractions (phasic) in the supine and standing position twice a week, for a total of 12 sessions. We evaluated

2012 Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia Controlled trial quality: uncertain

115. Insulin resistance improves metabolic and contractile efficiency in stressed rat heart Full Text available with Trip Pro

Insulin resistance improves metabolic and contractile efficiency in stressed rat heart Insulin resistance is a prominent feature in heart failure, while hyperglycemia impairs cardiac contraction. We propose that decreased insulin-mediated glucose uptake by the heart preserves cardiac function in response to metabolic and hemodynamic stress. To test this hypothesis, we fed rats a high-sucrose diet (HSD). Energy substrate metabolism and cardiac work were determined ex vivo in a sequential (...) protocol simulating metabolic and hemodynamic stress. Compared to chow-fed, control rats, HSD impaired myocardial insulin responsiveness and induced profound metabolic changes in the heart, characterized by reduced rates of glucose uptake (7.91 ± 0.30 vs. 10.73 ± 0.67 μmol/min/g dry weight; P<0.001) but increased rates of glucose oxidation (2.38 ± 0.17 vs. 1.50 ± 0.15 μmol/min/g dry weight; P<0.001) and oleate oxidation (2.29 ± 0.11 vs. 1.96 ± 0.12 μmol/min/g dry weight; P<0.05). Tight coupling

2012 The FASEB Journal

116. Rectal balloon training as an adjunctive method for pelvic floor muscle training in conservative management of stress urinary incontinence: a pilot study. (Abstract)

Rectal balloon training as an adjunctive method for pelvic floor muscle training in conservative management of stress urinary incontinence: a pilot study. Pelvic floor muscle training (PFMT) is currently considered as the first line conservative management for women with stress urinary incontinence (SUI). However, it is difficult for some women to self-identify the contraction of the pelvic floor muscle after they were trained by verbal instruction. Various techniques including rectal balloon (...) probe have been developed to improve PFMT.To compare vaginal squeezing pressure, one-hour pad test, leakage episodes, rating scores about severity of SUI, and patient satisfaction between traditional PFMT and rectal balloon training (RBT).Twenty-eight patients with SUI were randomized into two groups, PFMT, and RBT groups. The PFMT group was verbally instructed to perform exercise as the traditional technique. In the RBT group, a Foley catheter filled with tap water to create balloon was inserted

2012 Journal of the Medical Association of Thailand = Chotmaihet thangphaet Controlled trial quality: uncertain

117. Diagnosed With Chronic Hepatitis B? What Does Your HBV DNA Test Tell You?

had a verbal fight with my doctor because she says there is no need to make any tumor or cancer tests ….. Can you please answer me if it is possible my LDH level to indicate that I am developing some cancer even if all the rest of the results are in normal values and even if I have a good response from the medications . Please tell me your opinion because I am all in stress and in panic because the LDH is 531 Thank you very much Hello: I agree with your doctor, the antivirals used for HIV (...) treatment also work to suppress the hepatitis B virus. Please trust your doctor, especially if she is experiencing in treating HIV and hepatitis B. I know this is a stressful time. Good luck. Dear doctor, I am hepatitis B positive, I got to know my status in September, 2016, my viral load at the time was 2787 COI, I started using some herbal medicine and I went to do another test in January 2017 and my viral load was 272 IU/ML,. Kindly please advise me on this result.. Kindly note the difference in unit

2016 hepbblog

118. Selection against small males in utero: a test of the Wells hypothesis. Full Text available with Trip Pro

Selection against small males in utero: a test of the Wells hypothesis. The argument that women in stressful environments spontaneously abort their least fit fetuses enjoys wide dissemination despite the fact that several of its most intuitive predictions remain untested. The literature includes no tests, for example, of the hypothesis that these mechanisms select against small for gestational age (SGA) males.We apply time-series modeling to 4.9 million California male term births to test (...) the hypothesis that the rate of SGA infants in 1096 weekly birth cohorts varies inversely with labor market contraction, a known stressor of contemporary populations.We find support for the hypothesis that small size becomes less frequent among term male infants when the labor market contracts.Our findings contribute to the evidence supporting selection in utero. They also suggest that research into the association between maternal stress and adverse birth outcomes should acknowledge the possibility

2012 Human Reproduction

119. Test your medicine knowledge: 62-year-old man is evaluated during a routine visit

cholesterol level of 150 mg/dL (3.89 mmol/L). Electrocardiogram is within normal limits. Echocardiogram from 1 year ago shows a peak velocity of 2.0 m/s, mean transaortic gradient of 13 mm Hg, aortic valve area of 1.5 cm 2 , and preserved ejection fraction. Which of the following is the most appropriate management? A: Echocardiogram B: Exercise perfusion study C: Exercise stress test D: No additional testing MKSAP Answer and Critique The correct answer is D: No additional testing. This patient should (...) echocardiogram 1 year ago. He should undergo an annual clinical evaluation and echocardiography every 3 to 5 years. Echocardiography at this time in the absence of a clinical change is unnecessary. If a screening test were to be performed prior to exercise, an exercise stress test would be the most appropriate test; exercise perfusion imaging provides no additional information. In routine screening of patients with diabetes in the DIAD study, despite 22% of patients having evidence of perfusion defects

2015 KevinMD blog

120. Test your medicine knowledge: 48-year-old woman with type 2 diabetes mellitus

cholesterol level of 37 mg/dL (0.96 mmol/L). Urinalysis is negative for albuminuria. Her estimated 10-year cardiovascular risk by the Pooled Cohort Equations is 2.7%. Which of the following is the most appropriate cardiovascular disease risk management? A. Aspirin B. Coronary artery calcium scoring C. Exercise stress testing D. Folic acid supplementation E. No further testing or therapy MKSAP Answer and Critique The correct answer is E. No further testing or therapy. No further testing or therapy would (...) Test your medicine knowledge: 48-year-old woman with type 2 diabetes mellitus Should aspirin be routinely be given to patients with diabetes mellitus? Test your medicine knowledge: 48-year-old woman with type 2 diabetes mellitus | | October 31, 2015 10 Shares Test your medicine knowledge with the , in partnership with the . A 48-year-old woman is evaluated during a follow-up visit. She has a 5-year history of type 2 diabetes mellitus. She has no other significant medical history. Medications

2015 KevinMD blog

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