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Contraction Stress Test

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21. Microstructure-based constitutive model of coronary artery with active smooth muscle contraction (PubMed)

measurements while mechanical testing of arteries (n = 5) were performed in this study to validate the computational predictions. The proposed model not only provides predictions of active and passive stress distributions of vessel wall, but also enables reliable estimations of material parameters of individual fibers and cells and thus predicts microstructural stresses. The validated microstructural model of coronary artery sheds light on vascular biomechanics and can be extend to diseased vessels (...) Microstructure-based constitutive model of coronary artery with active smooth muscle contraction Currently, there is no full three-dimensional (3D) microstructural mechanical model of coronary artery based on measured microstructure including elastin, collagen and smooth muscle cells. Many structural models employ mean values of vessel microstructure, rather than continuous distributions of microstructure, to predict the mechanical properties of blood vessels. Although some models show good

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2017 Scientific reports

22. Functional implications of muscle co-contraction during gait in advanced age (PubMed)

-contraction and gait characteristics under normal and dual task conditions in healthy older adults (85.4±5.9years). We hypothesized that greater co-contraction is associated with slower gait speed during dual task conditions that stress executive and attentional abilities. Co-contraction was quantified during different phases of the gait cycle using surface electromyography (EMG) signals obtained from the anterior tibialis and lateral gastrocnemius while walking at preferred speed during normal and dual (...) task conditions. Variables included the time difference to complete the Trail Making Test A and B (ΔTMT) and gait measures during normal or dual task walking. Higher co-contraction levels during the swing phase of both normal and dual task walking were associated with longer ΔTMT (normal: R2=0.25, p=0.02; dual task: R2=0.27, p=0.01). Co-contraction was associated with gait measures during dual task walking only; greater co-contraction levels during stride and stance were associated with slower gait

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2017 Gait & posture Controlled trial quality: uncertain

23. HTA of HPV testing for cervical cancer screening

refers to identification of precancerous abnormalities that would not otherwise become clinically significant and may lead to increased surveillance, potentially increasing stress and anxiety, and or unnecessary treatment. Cervical cancer may develop in the time between a negative screening test and a woman’s next screening (interval cancer). This is another potential harm of any cervical screening programme. ? Primary HPV screening may result in worry and anxiety for some women. Potential issues (...) to the identification of precancerous abnormalities that would not otherwise have become clinically significant. Overdiagnosis may lead to increased surveillance, potentially increasing a woman’s stress and anxiety, and or unnecessary treatment. Cervical cancer may develop in the time interval between a negative screening test and the next scheduled screening, which is another potential harm of any cervical screening programme. As mentioned previously, there are three grades of CIN: CIN 1, CIN 2 and CIN 3. If left

2017 Health Information and Quality Authority

24. Biomarker tests to help diagnose preterm labour in women with intact membranes

Biomarker tests to help diagnose preterm labour in women with intact membranes Biomark Biomarker tests to help diagnose preterm er tests to help diagnose preterm labour in women with intact membr labour in women with intact membranes anes Diagnostics guidance Published: 4 July 2018 nice.org.uk/guidance/dg33 © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility This guidance (...) recommendations wherever possible. Biomarker tests to help diagnose preterm labour in women with intact membranes (DG33) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 36Contents Contents 1 Recommendations 4 2 Clinical need and practice 5 The problem addressed 5 The condition 5 The diagnostics and care pathways 7 3 The diagnostic tests 10 The interventions 10 The comparators 13 4 Evidence 14 Clinical effectiveness 14

2018 National Institute for Health and Clinical Excellence - Diagnostics Guidance

25. Unilateral anterior knee pain is associated with increased patellar lateral position after stressed lateral translation. (PubMed)

with idiopathic unilateral AKP (30.9 years, 23.4 kg/m2, 43% males) were included within the present study. Both knees of all the patients were examined by conventional imaging, including the measurement of trochlear sulcus angle, Caton-Deschamps index, tibial tuberosity to trochlear groove distance, patellar tilt angle and patellar subluxation (both at rest and upon quadriceps contraction). Additionally, the same patients underwent stress testing (Porto Patella Testing Device); these measurements were taken (...) Unilateral anterior knee pain is associated with increased patellar lateral position after stressed lateral translation. To objectively compare side-to-side patellar position and mobility in patients with idiopathic unilateral anterior knee pain (AKP) using a stress-testing device concomitantly with magnetic resonance imaging. It is hypothesized that the painful knees present greater patellar mobility than the contralateral non-painful knees.From a total sample of 359 patients, 23 patients

2019 Knee Surgery, Sports Traumatology, Arthroscopy

26. Exercise Testing Oversights Underlie Missed and Delayed Diagnosis of Catecholaminergic Polymorphic Ventricular Tachycardia in Young Sudden Cardiac Arrest Survivors. (PubMed)

Exercise Testing Oversights Underlie Missed and Delayed Diagnosis of Catecholaminergic Polymorphic Ventricular Tachycardia in Young Sudden Cardiac Arrest Survivors. Catecholaminergic polymorphic ventricular tachycardia (CPVT) is characterized by adrenergically induced ventricular tachycardia, syncope, and sudden cardiac arrest (SCA). In the absence of structural disease, exercise-provoked premature ventricular contractions in bigeminy or couplets and nonsustained ventricular tachycardia (...) are highly predictive of CPVT.The purpose of this study was to determine the number of missed or delayed CPVT diagnoses attributable to exercise testing oversights in a cohort of young SCA survivors.A retrospective review of 101 young SCA survivors (younger than 35 years at the time of SCA) with otherwise structurally normal hearts was used to identify those with a missed or delayed CPVT diagnosis because of overlooked evidence or lack of an exercise stress test (EST) or catecholamine provocation test

2019 Heart Rhythm

27. Gene expression profiling and immunohistochemistry tests for personalised management of adjuvant chemotherapy decisions in early breast cancer ? a Rapid Assessment

Gene expression profiling and immunohistochemistry tests for personalised management of adjuvant chemotherapy decisions in early breast cancer ? a Rapid Assessment 2015 www.kce.fgov.be KCE REPORT 237 GENE EXPRESSION PROFILING AND IMMUNOHISTOCHEMISTRY TESTS FOR PERSONALISED MANAGEMENT OF ADJUVANT CHEMOTHERAPY DECISIONS IN EARLY BREAST CANCER A RAPID ASSESSMENT 2015 www.kce.fgov.be KCE REPORT 237 HEALTH TECHNOLOGY ASSESSMENT GENE EXPRESSION PROFILING AND IMMUNOHISTOCHEMISTRY TESTS (...) FOR PERSONALISED MANAGEMENT OF ADJUVANT CHEMOTHERAPY DECISIONS IN EARLY BREAST CANCER A RAPID ASSESSMENT LORENA SAN MIGUEL, JOAN VLAYEN, CHRIS DE LAET COLOPHON Title: Gene expression profiling and immunohistochemistry tests for personalised management of adjuvant chemotherapy decisions in early breast cancer – a Rapid Assessment Authors: Lorena San Miguel (KCE), Joan Vlayen (KCE), Chris De Laet (KCE) Project coordinator: Marijke Eyssen (KCE) Reviewers: Frank Hulstaert (KCE), Nancy Thiry (KCE) External experts

2015 Belgian Health Care Knowledge Centre

28. NephroCheck: A Bedside Biomarker Test to Identify Patients at Risk for Acute Kidney Injury

AKI is defined as stage 2 or 3 in the KDIGO classification. 7,19 Serum creatinine measurement and urine output have been the standard diagnostic tests for AKI for many years. Creatinine is a waste product produced by the muscles during the break down of creatine that produces energy for muscle contraction. Elevated levels of creatinine indicate impaired kidney function. 20 Determining the duration of AKI helps to distinguish it from chronic kidney disease (CKD), identify possible underlying causes (...) NephroCheck: A Bedside Biomarker Test to Identify Patients at Risk for Acute Kidney Injury NephroCheck: A Bedside Biomarker Test to Identify Patients at Risk for Acute Kidney Injury | CADTH.ca Find the information you need NephroCheck: A Bedside Biomarker Test to Identify Patients at Risk for Acute Kidney Injury NephroCheck: A Bedside Biomarker Test to Identify Patients at Risk for Acute Kidney Injury Published on: March 27, 2015 Project Number: EH0024 Product Line: Issue: Issue 131 Result type

2015 CADTH - Issues in Emerging Health Technologies

29. Using Work Ability Index and work-related stress to evaluate the physical and mental fitness of Iranian telecom tower climbers (PubMed)

-sectional study was conducted among employees of a contracting company which worked in the field of telecommunication tower installation in Iran during 2016. Sixty out of 93 workers voluntarily participated in this study. Data collection tools were the Persian version of the Work Ability Index (WAI), the Persian version of the Health and Safety Executive (HSE) Stress Indicator Tool and an author-developed measure to assess socio-demographic characteristics. Data was analyzed through statistical tests (...) such as independent t-test, univariate analyses of variance (ANOVAs), Pearson's correlation coefficient, and multivariate linear regression; using SPSS 19 software.Workers' mean ± SD WAI score was 29.17 ± 10.33 and for work-related stress was 3.08 ± 1.80. There was a significant relation between WAI and educational level, job tenure, hours of sleep per day, regular exercise, and second job. The repression modeling explained 67.4% of the total variance (adjusted R2) of the WAI score. Among the dimensions of work

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2018 Journal of Injury and Violence Research

30. Biomarkers of preconception stress and the incidence of pregnancy loss. (PubMed)

-amylase, biomarkers of stress. Women used home pregnancy tests on the day of expected menses. A pregnancy loss was defined as a negative pregnancy test following a positive pregnancy test, the onset of menses, or for pregnancies that survived to clinical recognition, recognition of the loss by a healthcare provider.Among the 337 couples, the median age of female and male partners was 29 and 31 years, respectively. Most of the women were non-Hispanic white (83%) and highly educated. There were 97 (...) -represented, therefore it is possible that the results might not be generalizable to all women.In one of the largest studies in the USA to prospectively capture data on the incidence of early pregnancy loss, we found no clear association between two biomarkers of preconception stress (measured in saliva) and pregnancy loss.This study was supported by the Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (contracts #N01-HD-3-3355, N01-HD-3

2018 Human Reproduction

31. Perioperative Stress and Pain Perception of Second Eye Cataract Surgery

mentioned electrical conductance of the skin. It is used as an indication of psychological and physiological excitation and thus represents an indicator for the individual's stress response. Electromyograph (EMG) uses surface electrodes to measure the electrical activity of the skeletal muscles when they are relaxed and contracted by detecting the combined electrical potential generated by the muscle cells. The mean value of the rectified EMG signal of the upper trapezius muscle increases during (...) Perioperative Stress and Pain Perception of Second Eye Cataract Surgery Perioperative Stress and Pain Perception of Second Eye Cataract Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Perioperative

2018 Clinical Trials

32. Mechanical oscillations superimposed on the pelvic floor muscles during Kegel exercises reduce urine leakage in women suffering from stress urinary incontinence: a prospective cohort study with a two-year follow-up. (PubMed)

incontinence were included in this prospective cohort study. Vibration mechanosignals were superimposed during Kegel exercises using an intravaginal device. Each training session consisted of 15 maximal contractions of pelvic floor muscles for 5 s. The women performed training (5 min/day) at home for 4 (n = 60) and 6 (n = 36) weeks. Urine leakage (g) during stress test with standardized bladder volume, and contraction force without and with superimposed mechanical stimulations were measured at inclusion (...) (T0 ), and after 4 (T2 ) and 6 (T3 ) weeks of training using an intravaginal device. Incontinence Questionnaire-Short Form was recorded at T0 , and in a sub-cohort of women (n = 36) at 2 years follow up.Mean urine leakage reduced significantly from 20.5 (± 12.2) g at T0 to 4.8 (± 6.7) g at T2 and 1.5 (± 6.7) g at T3 . After 4 and 6 weeks of training, urinary leakage was ≤ 4 g on stress test in 44 and 49 of the 60 women, respectively. At T0 , the mean Incontinence Questionnaire-Short Form score

2018 Acta Obstetricia et Gynecologica Scandinavica

33. Mid Term Safety and Efficacy of ALTIS® Single Incision Sling for Female Stress Urinary Incontinence (SUI).

urinary incontinence surgery, menopause status, BMI and presence of urge incontinence) were collected. BMI was categorized according to World Health Organization in normal (18,5-24,9 Kg/m2), overweight (25-29,9 Kg/m2) and obese (≥ 30 Kg/m2) patients. For statistical purpose the investigators divided patients into two groups, non-obese (18,5-29,9) Kg/m2) and obese (≥ 30 Kg/m2) patients. Preoperative assessment included urogynecological history, cough test (stress test with at least 300 mL of bladder (...) volume measured by ultrasound), Spanish validated version of the International Consultation on Incontinence Questionnaire sort form (ICIQ-SF) and urodynamic test (Urodynamic parameters as Valsalva leak point pressure (VLPP), non-inhibited detrusor contractions and post-voiding volume were reflected. VLPP was categorized into three groups <60 cmH2O, 60-90 cmH2O and >90 cmH2O). Follow up was carried out with physical examination, ICIQ-SF, visual scale of satisfaction and physical examination including

2018 Clinical Trials

34. Canadian Experience With Contiform Intravaginal Device For The Treatment Of Stress Incontinence

a medical history and physical examination, a urinalysis, a urine culture, three-day voiding diary and post-void residual (PVR). Urodynamic testing will not be required. Kegel assessment will be performed on physical pelvic exam based on the Oxford subjective scale, which ranged from 0 (no palpable contraction) to 5 (very strong contraction). Demographic and baseline characteristics of the participants will be recorded, medical condition and medication. Patients will be offered the Contiform device (...) with self-insertion and self-removal. The device can be worn continuously for 1 month. When placed in the vagina it retains its shape and supports the urethra during episodes of varied intraabdominal pressure. During the assessment test (24 hours pad test), patients will be encouraged to undertake any activity that would normally induce stress leakage. The contiform device is approved by Health Canada since 2017-04-10 (Licence No.: 98950, Company ID: 134089, Device identifier: SKU 184) Outcome Measures

2018 Clinical Trials

35. Comparing Use of a Digital Health System of Pelvic Floor Exercise Program to Kegel Exercises in Stress Urinary Incontinence

change in pelvic floor muscle function resulting from pelvic floor muscle exercises. Active Comparator: Kegel Arm Subjects in this arm will perform pelvic floor muscle exercises (Kegels) for the treatment of stress or mixed urinary incontinence. Subjects will be asked to perform exercises three times daily for 8 weeks. At the beginning of the study, four weeks later, and eight weeks later, subjects will undergo pelvic floor muscle testing (using the PFDx device) and surveys to document response (...) Comparing Use of a Digital Health System of Pelvic Floor Exercise Program to Kegel Exercises in Stress Urinary Incontinence Comparing Use of a Digital Health System of Pelvic Floor Exercise Program to Kegel Exercises in Stress Urinary Incontinence - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached

2018 Clinical Trials

36. Oxidative Stress in Women Treated With Atosiban for Impending Preterm Birth

Oxidative Stress in Women Treated With Atosiban for Impending Preterm Birth Oxidative Stress in Women Treated With Atosiban for Impending Preterm Birth - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Oxidative Stress in Women Treated With Atosiban for Impending Preterm Birth The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03570294 Recruitment Status : Active, not recruiting First Posted : June 26, 2018 Last Update Posted : June 27, 2018 Sponsor: Polish Mother Memorial Hospital Research Institute

2018 Clinical Trials

37. Stress & Anxiety Dampening Effects of a Probiotic Supplement Compared to Placebo in Healthy Subjects

and questionnaires will be assessed before, during and after the Trier Social Stress Test (TSST). The results of this study indicate if the chosen study design is suitable to discover stress-related effects of probiotics. Condition or disease Intervention/treatment Phase Healthy Stress, Psychological Dietary Supplement: Lpc-37 Dietary Supplement: Placebo Not Applicable Detailed Description: The total mass of microorganisms residing within the human intestine is approximately the same as that of the human brain (...) Stress & Anxiety Dampening Effects of a Probiotic Supplement Compared to Placebo in Healthy Subjects Stress & Anxiety Dampening Effects of a Probiotic Supplement Compared to Placebo in Healthy Subjects - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2018 Clinical Trials

38. The Knack on Female Stress Urinary Incontinence

and of 11 to 50 grams as moderate stress urinary incontinence. The sample will also include women with grade 2 muscle strength (normal contraction with elevation of the anterior vaginal wall) on the two-finger assessment rated according to the Oxford scale. The primary outcome measure will be the objective cure of urinary incontinence as assessed by means of the one-hour pad test three months after randomization. Secondary outcome measures: three-day bladder diary, 1 hour pad test, International (...) Party): Fatima Fitz, Federal University of São Paulo Study Details Study Description Go to Brief Summary: The aim of the present study is to test the hypothesis that voluntary pelvic floor muscle pre-contraction (the Knack) (alone) can be a treatment for urine leakage during efforts. For this purpose, the following parameters will be analysed and compared amongst 1) the Knack, 2) pelvic floor muscle training and 3) the Knack + pelvic floor muscle training groups: urine leakage as assessed by the pad

2018 Clinical Trials

39. Enhanced Metabolic Stress Augments Ischemic Preconditioning for Exercise Performance (PubMed)

of participants for whom a traditional IPC stimulus was not effective, the magnification of the IPC stress through muscle contractions while under occlusion led to a subsequent exercise performance response. These findings support that amplification of the ischemic preconditioning stimulus augments the effect for exercise capacity. (...) Enhanced Metabolic Stress Augments Ischemic Preconditioning for Exercise Performance Purpose: To identify the combined effect of increasing tissue level oxygen consumption and metabolite accumulation on the ergogenic efficacy of ischemic preconditioning (IPC) during both maximal aerobic and maximal anaerobic exercise. Methods: Twelve healthy males (22 ± 2 years, 179 ± 2 cm, 80 ± 10 kg, 48 ± 4 ml.kg-1.min-1) underwent four experimental conditions: (i) no IPC control, (ii) traditional IPC, (iii

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2018 Frontiers in physiology Controlled trial quality: uncertain

40. Supervision of Exercise Testing by Nonphysicians

Rehabilitation have consistently addressed this issue in subsequent iterations of their respective guidelines. , , , In 2000, the ACC/AHA/American College of Physicians–American College of Internal Medicine Competency Task Force focused its efforts on outlining the specific cognitive and training requirements for those personnel involved with the supervision and interpretation of exercise ECG testing and with stress imaging tests administered to adults, children, and adolescents. That seminal document (...) by nonphysician staff who are deemed competent according to the criteria as outlined in the ACC/AHA statement ; a physician is always immediately available to assist as needed (ie, to provide direct supervision as defined in ); and in high-risk patients, the physician personally supervises the test (as defined in ). Table 1. Summary of Guideline Recommendations for Nonphysician Supervision of Exercise Tests Organization Guideline /Year Recommendation AHA/ACC “Clinical Competence Statement on Stress Testing

2014 American Heart Association

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