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Contraction Stress Test

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21. Ovariectomy and obesity have equal impact in causing mitochondrial dysfunction and impaired skeletal muscle contraction in rats. (Abstract)

hypothesis was that estrogen deficiency aggravates skeletal muscle dysfunction in obese-insulin resistant rats, via increased muscle oxidative stress and mitochondrial dysfunction.Twenty-four female Wistar rats were divided into 2 groups and animals in each group were fed either a normal diet (ND) or a high-fat diet (HFD) for 24 weeks. At week 13, rats in each group were subdivided into 2 subgroups: sham-operated or ovariectomized (n = 6/subgroup). At the end of the experimental period the contraction (...) of the gastrocnemius muscles was tested before the rats were sacrificed. Skeletal muscle was removed to assess oxidative stress and mitochondrial function.We found that an obese-insulin resistant condition was observed in sham-operated HFD-fed rats, ovariectomized ND-fed rats, and ovariectomized HFD-fed rats. Skeletal muscle contractile function (peak-force ratio [g/g]; 25.40 ± 2.03 [ovariectomized ND-fed rats], 22.44 ± 0.85 [sham-operated HFD-fed rats] and 25.06 ± 0.61 [ovariectomized HFD-fed rats]), skeletal

2018 Menopause

22. Effect of Radical Prostatectomy on Involuntary Pelvic Floor Muscle Contraction

29, 2018 See Sponsor: Pierre and Marie Curie University Information provided by (Responsible Party): Gérard Amarenco, Pierre and Marie Curie University Study Details Study Description Go to Brief Summary: This study evaluate the effect of radical prostatectomy on involuntary pelvic floor muscle contraction Condition or disease Lower Urinary Tract Symptoms Detailed Description: Radical prostatectomy may cause stress urinary incontinence (SUI). That poses problem in terms of quality of life (...) contraction. Intercostals muscles recording was chosen because they are one of the muscular components of cough initiation with diaphragm muscle. 24h pad-weighing test is used to quantify urinary incontinence. We will measure the latency between the onset of the EIC EMG and the EAS EMG (RT3), during a cough effort. We will also measure the duration of the contraction, the maximum EAS EMG activity and the area under the curve. Study Design Go to Layout table for study information Study Type : Observational

2018 Clinical Trials

23. Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients

Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients LABORATORY MEDICINE PRACTICE GUIDELINES EDITED BY LORALIE J. LANGMAN AND PAUL J. JANNETTO Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients Co-Sponsored byLABORATORY MEDICINE PRACTICE GUIDELINES Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients Loralie J. Langman Committee Chair Department of Laboratory Medicine and Pathology Mayo Clinic (...) prominently at the front of the document: Reproduced (translated) with permission of AACC, Washington, DC. This document (PID 11774) was approved by the AACC Board of Directors in November 2017.LABORATORY MEDICINE PRACTICE GUIDELINES Executive Summary 5 Preamble 34 Introduction 38 Chapter 1: Testing for common classes of relevant over-the-counter, prescribed, and non-prescribed drugs and illicit substances abused by pain management patients 47 Chapter 2: Specimen types and detection times 52 Chapter 3

2018 American Academy of Pain Medicine

24. Development and Usability Testing of EPC Evidence Review Dissemination Summaries for Health Systems Decisionmakers

and Usability Testing of EPC Evidence Review Dissemination Summaries for Health Systems Decisionmakers. Methods Research Report. (Prepared by the University of Alberta Evidence- based Practice Center under Contract No. 290-290-2015-00001-I). AHRQ Publication No. 18(19)-EHC027-EF. Rockville, MD: Agency for Healthcare Research and Quality. November 2018. Posted final reports are located on the Effective Health Care Program search page. https://doi.org/10.23970/AHRQEPCMETHENGAGEDEVELOPMENT. iv Preface (...) Development and Usability Testing of EPC Evidence Review Dissemination Summaries for Health Systems Decisionmakers Methods Research Report Development and Usability Testing of EPC Evidence Review Dissemination Summaries for Health Systems Decisionmakers Methods Research Report Development and Usability Testing of EPC Evidence Review Dissemination Summaries for Health Systems Decisionmakers Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540

2018 Effective Health Care Program (AHRQ)

25. Surgical Treatment of Female Stress Urinary Incontinence (SUI): AUA/SUFU Guideline

in the supine position, the test may be repeated in the standing position to facilitate the diagnosis. Once the increase in abdominal pressure has subsided, flow through the urethra should subside as well. Rarely, one may witness urine loss after an increase in intra-abdominal pressure has subsided. In this scenario, the incontinence may be, at least in part, due to an involuntary detrusor contraction (stress-induced detrusor overactivity). The Panel felt that physicians should obtain the following details (...) may perform additional evaluations in patients with the following conditions: (Expert Opinion) Concomitant overactive bladder symptoms Failure of prior anti-incontinence surgery Prior pelvic prolapse surgery Cystoscopy and Urodynamics Testing Physicians should not perform cystoscopy in index patients for the evaluation of stress urinary incontinence unless there is a concern for urinary tract abnormalities. (Clinical Principle) Physicians may omit urodynamic testing for the index patient desiring

2017 American Urological Association

26. Surgical Treatment of Female Stress Urinary Incontinence (SUI): AUA/SUFU Guideline

witness urine loss after an increase in intra-abdominal pressure has subsided. In this scenario, the incontinence may be, at least in part, due to an involuntary detrusor contraction (stress- induced detrusor overactivity). The Panel felt that physicians should obtain the following details from the history, bladder diary, questionnaires, and/or pad testing. ? Characterization of incontinence (stress, urgency, mixed, continuous, without sensory awareness) ? Chronicity of symptoms ? Frequency, bother (...) in patients with the following conditions: (Expert Opinion) ? Concomitant overactive bladder symptoms ? Failure of prior anti-incontinence surgery ? Prior pelvic prolapse surgery CYSTOSCOPY AND URODYNAMICS TESTING 4. Physicians should not perform cystoscopy in index patients for the evaluation of stress urinary incontinence unless there is a concern for urinary tract abnormalities. (Clinical Principle) 5. Physicians may omit urodynamic testing for the index patient desiring treatment when stress urinary

2017 Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction

27. Clinical Practice Guideline for the Treatment of Posttraumatic Stress Disorder

Clinical Practice Guideline for the Treatment of Posttraumatic Stress Disorder Guideline Development Panel for the Treatment of Posttraumatic Stress Disorder in Adults Adopted as APA Policy February 24, 2017 PTSD CLINICAL PRACTICE GUIDELINE for the Treatment of Clinical Practice Guideline for the Treatment of Posttraumatic Stress Disorder (PTSD) in Adults American Psychological Association Guideline Development Panel for the Treatment of PTSD in Adults Adopted as APA Policy February 24, 2017 (...) GDP Members: Christine A. Courtois, Chair Jeffrey Sonis, Vice-Chair Laura S. Brown Joan Cook John A. Fairbank Matthew Friedman Joseph P. Gone Russell Jones Annette La Greca Thomas Mellman John Roberts Priscilla Schulz APA Guidelines Staff: Lynn F. Bufka Raquel Halfond Howard Kurtzman i Abstract Description: The American Psychological Association (APA) developed this guideline to provide recommendations on psychological and pharmacological treatments for posttraumatic stress disorder (PTSD

2017 American Psychological Association

28. HTA of HPV testing for cervical cancer screening

refers to identification of precancerous abnormalities that would not otherwise become clinically significant and may lead to increased surveillance, potentially increasing stress and anxiety, and or unnecessary treatment. Cervical cancer may develop in the time between a negative screening test and a woman’s next screening (interval cancer). This is another potential harm of any cervical screening programme. ? Primary HPV screening may result in worry and anxiety for some women. Potential issues (...) to the identification of precancerous abnormalities that would not otherwise have become clinically significant. Overdiagnosis may lead to increased surveillance, potentially increasing a woman’s stress and anxiety, and or unnecessary treatment. Cervical cancer may develop in the time interval between a negative screening test and the next scheduled screening, which is another potential harm of any cervical screening programme. As mentioned previously, there are three grades of CIN: CIN 1, CIN 2 and CIN 3. If left

2017 Health Information and Quality Authority

29. Can Women Correctly Contract Their Pelvic Floor Muscles After to Receive Verbal Instructions and Vaginal Palpation?

Incontinence Urinary Incontinence, Stress Urination Disorders Lower Urinary Tract Symptoms Other: Verbal instruction and Vaginal palpation Not Applicable Detailed Description: Research Questions: The objectives of this study is to test the hypothesis that the provision of verbal instructions about the anatomy and function of PFMs associated with the use of body techniques awareness and vaginal palpation helps in learning the correct contraction and improves the function of the PFMs. Design: A single (...) Can Women Correctly Contract Their Pelvic Floor Muscles After to Receive Verbal Instructions and Vaginal Palpation? Can Women Correctly Contract Their Pelvic Floor Muscles After to Receive Verbal Instructions and Vaginal Palpation? - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2017 Clinical Trials

30. Rapid versus slow ascending vasodilatation: intercellular conduction versus flow‐mediated signalling with tetanic versus rhythmic muscle contractions Full Text available with Trip Pro

that conducts along endothelium into FAs. Rhythmic twitch contractions stimulate FA endothelium to release nitric oxide in response to elevated shear stress secondary to metabolic dilatation of arterioles. Complementary endothelial signalling pathways for ascending vasodilatation ensure increased oxygen delivery to active skeletal muscle.In response to exercise, vasodilatation initiated within the microcirculation of skeletal muscle ascends the resistance network into upstream feed arteries (FAs) located (...) external to the tissue. Ascending vasodilatation (AVD) is essential for reducing FA resistance that otherwise restricts blood flow into the microcirculation. In the present study, we tested the hypothesis that signalling events underlying AVD vary with the intensity and duration of muscle contraction. In the gluteus maximus muscle of anaesthetized male C57BL/6 mice (aged 3-4 months), brief tetanic contraction (100 Hz for 500 ms) evoked rapid onset vasodilatation (ROV) in FAs that peaked within 4 s

2017 The Journal of physiology

31. Functional implications of muscle co-contraction during gait in advanced age Full Text available with Trip Pro

-contraction and gait characteristics under normal and dual task conditions in healthy older adults (85.4±5.9years). We hypothesized that greater co-contraction is associated with slower gait speed during dual task conditions that stress executive and attentional abilities. Co-contraction was quantified during different phases of the gait cycle using surface electromyography (EMG) signals obtained from the anterior tibialis and lateral gastrocnemius while walking at preferred speed during normal and dual (...) task conditions. Variables included the time difference to complete the Trail Making Test A and B (ΔTMT) and gait measures during normal or dual task walking. Higher co-contraction levels during the swing phase of both normal and dual task walking were associated with longer ΔTMT (normal: R2=0.25, p=0.02; dual task: R2=0.27, p=0.01). Co-contraction was associated with gait measures during dual task walking only; greater co-contraction levels during stride and stance were associated with slower gait

2017 Gait & posture Controlled trial quality: uncertain

32. Microstructure-based constitutive model of coronary artery with active smooth muscle contraction Full Text available with Trip Pro

measurements while mechanical testing of arteries (n = 5) were performed in this study to validate the computational predictions. The proposed model not only provides predictions of active and passive stress distributions of vessel wall, but also enables reliable estimations of material parameters of individual fibers and cells and thus predicts microstructural stresses. The validated microstructural model of coronary artery sheds light on vascular biomechanics and can be extend to diseased vessels (...) Microstructure-based constitutive model of coronary artery with active smooth muscle contraction Currently, there is no full three-dimensional (3D) microstructural mechanical model of coronary artery based on measured microstructure including elastin, collagen and smooth muscle cells. Many structural models employ mean values of vessel microstructure, rather than continuous distributions of microstructure, to predict the mechanical properties of blood vessels. Although some models show good

2017 Scientific reports

33. Economic stress or random variation? Revisiting German reunification as a natural experiment to investigate the effect of economic contraction on sex ratios at birth Full Text available with Trip Pro

Economic stress or random variation? Revisiting German reunification as a natural experiment to investigate the effect of economic contraction on sex ratios at birth The economic stress hypothesis (ESH) predicts decreases in the sex ratio at birth (SRB) following economic decline. However, as many factors influence the SRB, this hypothesis is difficult to test empirically. Thus, researchers make use of quasi-experiments such as German reunification: The economy in East, but not in West Germany

2014 Environmental Health

34. Impaired Cardiac Reserve on Dobutamine Stress Echocardiography Predicts the Development of Hepatorenal Syndrome. (Abstract)

disease.HRS is a life-threatening complication of liver disease. We studied whether an inability to increase cardiac contraction in response to stress can assist in the prediction of HRS. We demonstrate that patients with liver disease who exhibit cardiac dysfunction during stress testing had a 4-fold increased risk of developing HRS. This may improve our ability for early diagnosis and treatment of patients at a higher risk of developing HRS. (...) Impaired Cardiac Reserve on Dobutamine Stress Echocardiography Predicts the Development of Hepatorenal Syndrome. Cardiac dysfunction has been implicated in the genesis of hepatorenal syndrome (HRS). It is unclear whether a low cardiac output (CO) or attenuated contractile response to hemodynamic stress can predict its occurrence. We studied cardiovascular hemodynamics in cirrhosis and assessed whether a diminished cardiac reserve with stress testing predicted the development of HRS on follow

2020 American Journal of Gastroenterology

35. Effectiveness of breathing exercises, foot reflexology and back massage (BRM) on labour pain, anxiety, duration, satisfaction, stress hormones and newborn outcomes among primigravidae during the first stage of labour in Saudi Arabia: a study protocol for Full Text available with Trip Pro

Effectiveness of breathing exercises, foot reflexology and back massage (BRM) on labour pain, anxiety, duration, satisfaction, stress hormones and newborn outcomes among primigravidae during the first stage of labour in Saudi Arabia: a study protocol for Labour pain is among the severest pains primigravidae may experience during pregnancy. Failure to address labour pain and anxiety may lead to abnormal labour. Despite the many complementary non-pharmacological approaches to coping with labour (...) or pregnancy-related complications will be recruited from antenatal clinics. Eligible and consenting patients will be randomly allocated to the intervention or the control group stratified by intramuscular pethidine use. The BRM intervention will be delivered by a trained massage therapist. The primary outcomes of labour pain and anxiety will be measured during and after uterine contractions at baseline (cervical dilatation 6 cm) and post BRM hourly for 2 hours. The secondary outcomes include maternal

2020 BMJ open

36. Stress and the Surgical Resident in the COVID-19 Pandemic. Full Text available with Trip Pro

Stress and the Surgical Resident in the COVID-19 Pandemic. The COVID-19 pandemic has drastically transformed the healthcare community and medical education across the United States. The aim of this study was to evaluate the impact of COVID-19 on the surgical resident training experience, assess possible sources of stress or anxiety among surgery residents, and examine how patterns of anxiety vary by resident rank.We developed and disseminated a survey, which included the Generalized Anxiety (...) Disorder 7-Item Scale (GAD-7), to all general and integrated plastic surgery residents in their clinical years of training at the University of California, San Francisco. Statistical analysis of the survey responses was performed using the Kruskal-Wallis or Wilcoxon rank sum test. Post-hoc analysis was performed using the Bonferroni-corrected Dunn test. Survey data were combined with aggregated duty hour information and operative case numbers from select hospitals for March and April of 2019

2020 Journal of Surgical Education

37. Gene expression profiling and immunohistochemistry tests for personalised management of adjuvant chemotherapy decisions in early breast cancer ? a Rapid Assessment

Gene expression profiling and immunohistochemistry tests for personalised management of adjuvant chemotherapy decisions in early breast cancer ? a Rapid Assessment 2015 www.kce.fgov.be KCE REPORT 237 GENE EXPRESSION PROFILING AND IMMUNOHISTOCHEMISTRY TESTS FOR PERSONALISED MANAGEMENT OF ADJUVANT CHEMOTHERAPY DECISIONS IN EARLY BREAST CANCER A RAPID ASSESSMENT 2015 www.kce.fgov.be KCE REPORT 237 HEALTH TECHNOLOGY ASSESSMENT GENE EXPRESSION PROFILING AND IMMUNOHISTOCHEMISTRY TESTS (...) FOR PERSONALISED MANAGEMENT OF ADJUVANT CHEMOTHERAPY DECISIONS IN EARLY BREAST CANCER A RAPID ASSESSMENT LORENA SAN MIGUEL, JOAN VLAYEN, CHRIS DE LAET COLOPHON Title: Gene expression profiling and immunohistochemistry tests for personalised management of adjuvant chemotherapy decisions in early breast cancer – a Rapid Assessment Authors: Lorena San Miguel (KCE), Joan Vlayen (KCE), Chris De Laet (KCE) Project coordinator: Marijke Eyssen (KCE) Reviewers: Frank Hulstaert (KCE), Nancy Thiry (KCE) External experts

2015 Belgian Health Care Knowledge Centre

38. Unilateral anterior knee pain is associated with increased patellar lateral position after stressed lateral translation. (Abstract)

with idiopathic unilateral AKP (30.9 years, 23.4 kg/m2, 43% males) were included within the present study. Both knees of all the patients were examined by conventional imaging, including the measurement of trochlear sulcus angle, Caton-Deschamps index, tibial tuberosity to trochlear groove distance, patellar tilt angle and patellar subluxation (both at rest and upon quadriceps contraction). Additionally, the same patients underwent stress testing (Porto Patella Testing Device); these measurements were taken (...) Unilateral anterior knee pain is associated with increased patellar lateral position after stressed lateral translation. To objectively compare side-to-side patellar position and mobility in patients with idiopathic unilateral anterior knee pain (AKP) using a stress-testing device concomitantly with magnetic resonance imaging. It is hypothesized that the painful knees present greater patellar mobility than the contralateral non-painful knees.From a total sample of 359 patients, 23 patients

2019 Knee Surgery, Sports Traumatology, Arthroscopy

39. NephroCheck: A Bedside Biomarker Test to Identify Patients at Risk for Acute Kidney Injury

AKI is defined as stage 2 or 3 in the KDIGO classification. 7,19 Serum creatinine measurement and urine output have been the standard diagnostic tests for AKI for many years. Creatinine is a waste product produced by the muscles during the break down of creatine that produces energy for muscle contraction. Elevated levels of creatinine indicate impaired kidney function. 20 Determining the duration of AKI helps to distinguish it from chronic kidney disease (CKD), identify possible underlying causes (...) NephroCheck: A Bedside Biomarker Test to Identify Patients at Risk for Acute Kidney Injury NephroCheck: A Bedside Biomarker Test to Identify Patients at Risk for Acute Kidney Injury | CADTH.ca Find the information you need NephroCheck: A Bedside Biomarker Test to Identify Patients at Risk for Acute Kidney Injury NephroCheck: A Bedside Biomarker Test to Identify Patients at Risk for Acute Kidney Injury Published on: March 27, 2015 Project Number: EH0024 Product Line: Issue: Issue 131 Result type

2015 CADTH - Issues in Emerging Health Technologies

40. Exercise Testing Oversights Underlie Missed and Delayed Diagnosis of Catecholaminergic Polymorphic Ventricular Tachycardia in Young Sudden Cardiac Arrest Survivors. (Abstract)

Exercise Testing Oversights Underlie Missed and Delayed Diagnosis of Catecholaminergic Polymorphic Ventricular Tachycardia in Young Sudden Cardiac Arrest Survivors. Catecholaminergic polymorphic ventricular tachycardia (CPVT) is characterized by adrenergically induced ventricular tachycardia, syncope, and sudden cardiac arrest (SCA). In the absence of structural disease, exercise-provoked premature ventricular contractions in bigeminy or couplets and nonsustained ventricular tachycardia (...) are highly predictive of CPVT.The purpose of this study was to determine the number of missed or delayed CPVT diagnoses attributable to exercise testing oversights in a cohort of young SCA survivors.A retrospective review of 101 young SCA survivors (younger than 35 years at the time of SCA) with otherwise structurally normal hearts was used to identify those with a missed or delayed CPVT diagnosis because of overlooked evidence or lack of an exercise stress test (EST) or catecholamine provocation test

2019 Heart Rhythm

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