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1. Objective Assessment of Ocular Surface Response to Contact Lens Wear in Presbyopic Contact Lens Wearers of Asian Descent (PubMed)

Objective Assessment of Ocular Surface Response to Contact Lens Wear in Presbyopic Contact Lens Wearers of Asian Descent Contact lens wearers of Asian descent may be predisposed to experience microtrauma of the ocular surface as a result a thinner post-lens tear film and higher eyelid tension, and these effects would be anticipated to be most marked in an older population. The objective of this study was to quantify the mechanical effects of the study contact lenses on the ocular surface (...) in a population of presbyopic contact lens wearers of Asian descent.Twenty established presbyopic contact lens wearers (hydrogel n=5, none habitual wearers of etafilcon A lenses; silicone hydrogel n=15) of Asian descent were refitted with etafilcon A multifocal daily disposable contact lenses (1-DAY ACUVUE MOIST MULTIFOCAL) for a period of 1 month of daily lens wear. The habitual modalities of wear were 45% daily disposable and 55% planned replacement. Digital photographs of the upper lid margins, nasal

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2018 Eye & contact lens

2. The Impact of Soft Contact Lens Attributes on Symptoms Associated With Digital Eye Strain in Symptomatic Soft Contact Lens Wearers

The Impact of Soft Contact Lens Attributes on Symptoms Associated With Digital Eye Strain in Symptomatic Soft Contact Lens Wearers The Impact of Soft Contact Lens Attributes on Symptoms Associated With Digital Eye Strain in Symptomatic Soft Contact Lens Wearers - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have (...) reached the maximum number of saved studies (100). Please remove one or more studies before adding more. The Impact of Soft Contact Lens Attributes on Symptoms Associated With Digital Eye Strain in Symptomatic Soft Contact Lens Wearers The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03585790

2018 Clinical Trials

3. Identification of Leukocytes Associated With Midday Fogging in the Post-Lens Tear Film of Scleral Contact Lens Wearers. (PubMed)

Identification of Leukocytes Associated With Midday Fogging in the Post-Lens Tear Film of Scleral Contact Lens Wearers. Midday fogging is a frequent complaint among scleral contact lens (ScCL) wearers, and the mechanism and cause of this is unknown. The purpose of this investigation was to understand the relation between midday fogging, ocular surface leukocytes, and ScCL fitting characteristics.Subjects arrived at a clinical exam having worn ScCLs for at least 4 hours. ScCL were removed (...) , and 150 μL of phosphate-buffered saline (PBS) was used to wash the bowl of the ScCL. Eyes were washed post-ScCL removal with 5 mL PBS per eye. Wash solutions were collected and leukocytes were then isolated and counted, followed by assessment with flow cytometry. Samples from the post-lens tear fluid were stained with fluorescently labeled antibodies to detect leukocyte distributions.Thirty-nine eyes from 19 adapted, full-time, ScCL wearers were included, and 46% presented with midday fogging. ScCL

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2019 Investigative Ophthalmology & Visual Science

4. Knowledge and practice regarding contact lens among Saudi urban contact lens users (PubMed)

Knowledge and practice regarding contact lens among Saudi urban contact lens users To assess the level and determinants of knowledge and practice regarding contact lens (CL) and its accessories among adult Saudi CL users.This survey was conducted in 2015 for Saudi contact lens users visiting a Mall in Riyadh, Saudi Arabia. The questions were related to knowledge about contact lenses, correct CL and accessories usage. We inquired indication, initial prescription, CL use, complications (...) experienced and their management. The knowledge and practice responses were correlated to their determinants.In this survey, 510 contact lens users participated. The level of knowledge was of excellent grade among 279 [54.7% (95% Confidence Interval 50.4-59)] CL users. The practice was of excellent grade in 210 [41.4% (95% CI 37.1-45.7)] CL users. Variation in knowledge was not associated to gender (P = 0.1), education (P = 0.4), type of work (P = 0.3), funding for CL (P = 0.1). Occasional users and those

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2017 Saudi Journal of Ophthalmology

5. Improved vision and contact lens wear time with Piggy-Back Contact Lens Systems in children after penetrating corneal trauma (PubMed)

Improved vision and contact lens wear time with Piggy-Back Contact Lens Systems in children after penetrating corneal trauma Consecutive case series of children treated successfully with "piggy-back" (PB) contact lens systems after corneal trauma.We reviewed the medical record of all children ages 4 to 14 years treated at the Emory Eye Center between January 11, 2003 and January 11, 2013 with PB contact lens systems.Four children with a history of corneal penetrating trauma were treated (...) with a PB lens system, with a mean age of 7±0.08 (range: 6-8) years. Best-corrected spectacle vision was count fingers in two children and logMAR +0.70 (Snellen equivalent 20/100) and logMAR +0.6 (Snellen equivalent 20/80) in the remaining two. The PB lens system was introduced with a mean of 15.7±6.5 (range: 9-22) months after the injury. All patients were initially fitted with gas-permeable (GP) lenses. Each child achieved 11 or more hours of daily contact lens wear time in PB systems. The mean best

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2017 Eye & contact lens

6. The influence of lens care systems on eyelid tissue changes during silicone hydrogel contact lens wear. (PubMed)

The influence of lens care systems on eyelid tissue changes during silicone hydrogel contact lens wear. To compare the effects of a hydrogen peroxide (H2O2)-based lens care solution and a polyhexamethylene biguanide (PHMB) multi-purpose solution on the eyelids when used with silicone hydrogel (SiHy) contact lenses.A total of 74 symptomatic wearers of ACUVUE® OASYS® (senofilcon A; n = 39) or PureVision® (balafilcon A; n = 35) contact lenses were randomised 1:1 to either CLEAR CARE® Cleaning (...) & Disinfecting Solution or renu® fresh™ multi-purpose solution (n = 37 each). Assessments of hyperaemia, papillae and lid margin staining of eyelid tissue were evaluated subjectively by a masked investigator at enrolment (with the subjects' habitual SiHy contact lenses and PHMB-preserved care systems), at dispensing visit (when no lenses were worn) and at 3-months' follow-up.There were no differences in eyelid assessments between the two lens care groups at dispensing visit (p = 0.086 to 0.947). After 3

2018 Contact lens & anterior eye : the journal of the British Contact Lens Association Controlled trial quality: uncertain

7. Efficacy of Toric Contact Lenses in Fitting and Patient-Reported Outcomes in Contact Lens Wearers. (PubMed)

Efficacy of Toric Contact Lenses in Fitting and Patient-Reported Outcomes in Contact Lens Wearers. To assess whether patient-reported measures are improved with soft toric contact lenses (TCLs) compared with soft spherical contact lenses (SCLs) and whether clinical time needed to fit TCL is greater than SCL.Habitual contact lens wearers with vertexed spherical refraction +4.00 to +0.25 D or -0.50 to -9.00 D and cylinder -0.75 to -1.75 DC were randomly assigned to be binocularly fitted (...) for the NEI-RQL-42.Sixty subjects (71.7% women, mean age [±SD] = 27.5±5.0 years) completed the study. The mean time to fit the TCL was 10.2±4.3 and 9.0±6.5 min for the SCL (least square [LS] mean difference (TCL-SCL)=1.2, P=0.22). Toric contact lens scored better than SCL in global NEI-RQL-42 score (P=0.006) and the clarity of vision (P=0.006) and satisfaction with correction subscales (P=0.006). CISS showed a 15% reduction in symptoms (LS mean difference [TCL-SCL]=-2.20, P=0.02).TCLs are a good option

2018 Eye & contact lens Controlled trial quality: uncertain

8. Pilot Study for Investigating the Effect of the Bruder Eye Hydrating Compress on Contact Lens Discomfort in Contact Lens Wearers

Pilot Study for Investigating the Effect of the Bruder Eye Hydrating Compress on Contact Lens Discomfort in Contact Lens Wearers Pilot Study for Investigating the Effect of the Bruder Eye Hydrating Compress on Contact Lens Discomfort in Contact Lens Wearers - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have (...) reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Pilot Study for Investigating the Effect of the Bruder Eye Hydrating Compress on Contact Lens Discomfort in Contact Lens Wearers The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02848222 Recruitment

2016 Clinical Trials

9. Conjunctival Microbiome Changes Associated With Soft Contact Lens and Orthokeratology Lens Wearing. (PubMed)

Conjunctival Microbiome Changes Associated With Soft Contact Lens and Orthokeratology Lens Wearing. Usage of different types of contact lenses is associated with increased risk of sight-threatening complications. Changes in the ocular microbiome caused by contact lens wear are suggested to affect infection development in those individuals. To address this question, this study compares conjunctival microbial communities in contact lens wearers with those in noncontact lens wearers.Paired-end (...) sequencing of the V3 region of the 16S rRNA gene was used to characterize the bacterial communities on the conjunctival surfaces of contact lens wearers and nonwearers.No differences in microbial diversity were detected between contact lens wearers and nonwearers. Nevertheless, some slight microbe variability was evident between these two different groups. Bacillus, Tatumella and Lactobacillus abundance was less in orthokeratology lens (OKL) wearers than in nonwearers. In soft contact lenses (SCL

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2017 Investigative Ophthalmology & Visual Science

10. The impact of lens care solutions on corneal epithelial changes during daily silicone hydrogel contact lens wear as measured by in vivo confocal microscopy. (PubMed)

The impact of lens care solutions on corneal epithelial changes during daily silicone hydrogel contact lens wear as measured by in vivo confocal microscopy. To assess corneal epithelial microstructure via confocal microscopy and determine if cellular changes are associated with lens care solutions during daily wear of silicone hydrogel contact lenses.Corneal in vivo confocal microscopy with the Nidek ConfoScan4 was performed at baseline and after 5 months of lotrafilcon A daily contact lens (...) lens wear. Hyper-reflective superficial epithelial cells are associated with a PHMB preserved solution and decreases in basal epithelial cell density may be associated with bacterial bioburden.Copyright © 2016 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

2017 Contact lens & anterior eye : the journal of the British Contact Lens Association Controlled trial quality: uncertain

11. The Effect of Therapeutic IOP-lowering Interventions on the Twenty-four Hour Ocular Dimensional Profile Recorded with a Sensing Contact Lens. (PubMed)

The Effect of Therapeutic IOP-lowering Interventions on the Twenty-four Hour Ocular Dimensional Profile Recorded with a Sensing Contact Lens. PRéCIS:: The 24-hour ocular dimensional profile recorded by a contact lens sensor was affected by intraocular pressure lowering interventions. Among different treatments, incisional surgery had the most significant effect.We investigated the effect of different intraocular pressure (IOP)-lowering interventions on contact lens sensor (CLS) parameters

2019 Journal of Glaucoma

12. Fluctuations of the intraocular pressure in medically versus surgically treated glaucoma patients by a contact lens sensor. (PubMed)

Fluctuations of the intraocular pressure in medically versus surgically treated glaucoma patients by a contact lens sensor. To compare fluctuations in intraocular pressure (IOP) in medically versus surgically treated glaucoma patients.Prospective, non-randomized case series.IOP-related fluctuations were measured for 24 hours using a contact lens sensor (CLS).We perform monitoring with CLS in 91 eyes of 77 patients; 59 eyes were receiving ocular hypotensive medication and had no previous history

2019 American Journal of Ophthalmology

13. Efficacy of therapeutic soft contact lens in the management of gelatinous drop-like corneal dystrophy. (PubMed)

Efficacy of therapeutic soft contact lens in the management of gelatinous drop-like corneal dystrophy. To investigate the efficacy of therapeutic soft contact lenses (SCLs) in gelatinous drop-like corneal dystrophy (GDLD) management.This was a retrospective, consecutive, observational case series, including 20 patients (40 eyes) with GDLD treated in Osaka University Hospital within the last 15 years. We tested the effects of therapeutic SCL on clinical features, visual acuity and surgical

2019 British Journal of Ophthalmology

14. Influence of Ocular Dimensional Change on 24-hour Intraocular Pressure Measurement with Contact Lens Sensor. (PubMed)

Influence of Ocular Dimensional Change on 24-hour Intraocular Pressure Measurement with Contact Lens Sensor. We measured changes in the corneal morphology and intraocular pressure (IOP) before and after the use of contact lens sensor (CLS). Then, we investigated whether the ocular dimensional change affected the measured IOP value with CLS.In this prospective study, we examined 112 eyes of glaucoma patients. We measured the IOP fluctuation using a Sensimed Triggerfish® CLS. We measured

2019 Journal of Glaucoma

15. Bandage contact lens use after photorefractive keratectomy. (PubMed)

Bandage contact lens use after photorefractive keratectomy. The use of a bandage contact lens (BCL) immediately after photorefractive keratectomy (PRK) results in less pain. This review analyzed which BCL is most effective in decreasing pain immediately after PRK and evaluated the reepithelialization process in the treated zone. Two databases, PubMed and Medline, were checked for articles published from January 2005 to May 2018. The keywords were photorefractive keratectomy, PRK, contact lens (...) , and bandage contact lens. The review comprised 13 studies; these studies enrolled 842 patients who had PRK. All studies compared the early postoperative results for two types of BCL material (senofilcon A and lotrafilcon A). Of the materials, the pain scores were lowest with a senofilcon A. The size of the defect in the epithelialized area 1 day after surgery decreased fastest with lotrafilcon A.Copyright © 2019 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

2019 Journal of cataract and refractive surgery

16. Non-invasive Intraocular pressure monitoring with contact lens. (PubMed)

Non-invasive Intraocular pressure monitoring with contact lens. Glaucoma is the second leading cause of blindness in the world and the first leading cause of irreversible vision loss. Currently, the primary methodology of testing for the intraocular pressure (IOP) is during clinical office hours, which only provide a limited amount of information on the trends and fluctuations of the IOP. Therefore, a continuous monitoring system is required to properly determine the peaks of pressure (...) and to negate any false results obtained by sparse, clinic hour testing. The objective of this study is to determine the ability of a newly designed contact lens with an embedded microchannel, to accurately measure the fluctuations in the IOP.Experimentation was completed on fresh enucleated porcine eyes. The contact lens was placed on the porcine eye and utilising a camera the fluid movement, within the microchannel in the contact lens, was recorded. A micro-pressure catheter, threaded into the centre

2019 British Journal of Ophthalmology

17. The effect of soft contact lens thickness in visual function after intracorneal ring segments surgery. (PubMed)

The effect of soft contact lens thickness in visual function after intracorneal ring segments surgery. To study the influence of soft contact lens (SCL) central thickness and material in keratoconus on visual function after intracorneal ring segment (ICRS) surgery.A pilot, experimental, prospective, cross-sectional and double-blind study was performed. Fourteen keratoconus patients with age range of 34.75±9.22years (7 males and 7 females) with ICRS implanted were involved in the study. Two (...) not influence the HOA correction.Copyright © 2017 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

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2019 Contact lens & anterior eye : the journal of the British Contact Lens Association Controlled trial quality: uncertain

18. Effect of contact lens surface properties on comfort, tear stability and ocular physiology. (PubMed)

Effect of contact lens surface properties on comfort, tear stability and ocular physiology. Retrospective analysis of different contact lens wearing groups suggests lens surface lubricity is the main factor influencing contact lens comfort. However, the examined commercially available contact lenses differ in material and design as well as surface properties. Hence this study isolates the contribution of lens surface properties using an ultra-thin coating technology.Nineteen habitual contact (...) lens wearers (21.6±1.7years) wore formofilcon B soft monthly disposable contact lenses with and without coating technology modified surface properties for a month each in a randomised double-masked cross-over study. OBJECTIVE NON-INVASIVE: breakup time (NIKBUT), NIKBUT average and ocular redness (Jenvis grading scale) were evaluated (Keratograph 5M) after 1 week and 1 month of wear. Symptoms were assessed using the Contact Lens Dry Eye Questionnaire (CLDEQ-8); perceived vision quality

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2019 Contact lens & anterior eye : the journal of the British Contact Lens Association Controlled trial quality: uncertain

19. Exploring the links between contact lens comfort, osmolarity and lid wiper staining. (PubMed)

Exploring the links between contact lens comfort, osmolarity and lid wiper staining. Contact lens discomfort remains poorly understood, not least due to lack of associations between clinical signs and symptoms. This study aimed to explore the relationships between osmolarity, comfort and lid wiper epitheliopathy in contact lens wear.Twenty subjects participated in a randomized, cross-over study where comfilcon A and lotrafilcon A lenses were each worn for 10days separated by a 7days washout (...) period. Tear and contact lens osmolarity, ocular symptoms including comfort, tear stability and production, and lid wiper epitheliopathy were measured.Comfort and tear stability decreased and upper lid wiper staining and foreign body sensation increased with lens wear. These were not affected by lens type. A reduction in tear production was seen after 10days of comfilcon A lens wear. High proportions of lid wiper epitheliopathy were observed at the upper (range 65%-85%) and lower (range 90%-100%) lid

2019 Contact lens & anterior eye : the journal of the British Contact Lens Association Controlled trial quality: uncertain

20. Efficacy of an ocular bandage contact lens for the treatment of dry eye after phacoemulsification. (PubMed)

Efficacy of an ocular bandage contact lens for the treatment of dry eye after phacoemulsification. To evaluate the safety and efficacy of a bandage contact lens for alleviating dry eye discomfort after phacoemulsification.In this prospective, controlled study, 60 age-related cataract patients with mild Meibomian gland dysfunction (MGD) were randomized to treatment with an ocular bandage contact lens (BCL) (n = 30) or to an untreated control group (n = 30) after phacoemulsification (...) and intraocular lens implantation. The Ocular Surface Disease Index (OSDI) questionnaire, evaluation of subjective symptoms and evaluation of the best-corrected visual acuity (BCVA) were conducted preoperatively and postoperatively on days 1, 7, 14, 30 and 90. The tear breakup time (TBUT), Schirmer test with anesthesia, and fluorescein staining scores were measured preoperatively and postoperatively on days 7, 14, 30 and 90.There were no significant differences with respect to the BCVA between the groups

2019 BMC Ophthalmology Controlled trial quality: uncertain

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