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Congenital Heart Disease Imaging in Adults

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161. Effects of Dietary Sodium and Potassium Intake on Chronic Disease Outcomes and Risks

No. 18-EHC009-EF June 2018ii Key Messages Purpose of Review To synthesize the evidence regarding the effects of dietary sodium reduction and increased potassium intake on blood pressure and risk for cardiovascular diseases (CVD) and renal disease outcomes and related risk factors. Key Messages • Decreasing dietary sodium intake most likely reduces blood pressure in normotensive adults and more so in those with hypertension. • Higher sodium intake may be associated with greater risk for developing (...) (CVD), diabetes, or obesity and that assessed blood pressure (BP), incident hypertension, achievement of prespecified blood pressure goals, all-cause mortality, CVD morbidity and mortality, coronary heart disease morbidity and mortality, stroke, myocardial infarction, renal morbidity and mortality, kidney stones, and adverse events. We extracted data, assessed risk of bias (RoB, or study quality), summarized and synthesized results, and evaluated the strength of the evidence (SoE) supporting

2018 Effective Health Care Program (AHRQ)

162. Cardiopulmonary Resuscitation in Infants and Children With Cardiac Disease

of English-language articles from 1966 to 2015, cross-referencing congenital and acquired heart disease with pertinent MESH search terms, as follows: acute cardiac tamponade; acute kidney injury; adoles- cent; adult; amiodarone; aortic valve insufficiency/sur - gery; aortic valve stenosis/congenital; aortic valve steno- sis/surgery; aortic valve stenosis/therapy; arrhythmias, cardiac; atropine; bicarbonates; biomarkers; calcium; cardiac arrest; cardiac catheterization; cardiac output, low; cardiac (...) Chitra Ravishankar, MD Ricardo A. Samson, MD Ravi R. Thiagarajan, MBBS, MPH Rune Toms, MD James Tweddell, MD, FAHA Peter C. Laussen, MBBS, Co-Chair On behalf of the American Heart Association Congenital Cardiac Defects Committee of the Council on Cardiovascular Disease in the Young; Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Cardio- vascular Surgery and Anesthe- sia; and Emergency Cardiovas- cular Care Committee Cardiopulmonary Resuscitation in Infants

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2018 American Heart Association

163. Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks

-EHC009-EF June 2018ii Key Messages Purpose of Review To synthesize the evidence regarding the effects of dietary sodium reduction and increased potassium intake on blood pressure and risk for cardiovascular diseases (CVD) and renal disease outcomes and related risk factors. Key Messages • Decreasing dietary sodium intake most likely reduces blood pressure in normotensive adults and more so in those with hypertension. • Higher sodium intake may be associated with greater risk for developing (...) (CVD), diabetes, or obesity and that assessed blood pressure (BP), incident hypertension, achievement of prespecified blood pressure goals, all-cause mortality, CVD morbidity and mortality, coronary heart disease morbidity and mortality, stroke, myocardial infarction, renal morbidity and mortality, kidney stones, and adverse events. We extracted data, assessed risk of bias (RoB, or study quality), summarized and synthesized results, and evaluated the strength of the evidence (SoE) supporting

2018 Effective Health Care Program (AHRQ)

164. Task Force 2: Pediatric Cardiology Fellowship Training in Noninvasive Cardiac Imaging

-dimensional, and speckle tracking to assess global and regional deformation, color Doppler imaging, as well as pulsed and continuous- wave spectral Doppler imaging for flow, hemodynamics, and tissue motion. Cardiac MRI refers to anatomic and functional cardiovascular MRI for assessment of congenital heart disease (CHD) in children and adults, as well as for assessment of acquired forms of heart disease in children. 1.3. Levels of Expertise—Core and Advanced Innovations in the field of echocardiography (...) in February 2015. It was endorsed by the American Society of Echocardiography and approved by the ACC in March 2015. This document is considered current until the SPCTPD revises or withdraws it. 1.2. Background and Scope For over 25 years, noninvasive cardiac imaging has been the mainstay of anatomic and physiological assessment in pedi- atric cardiology and congenital heart disease. An ACC/AAP/ AHA combined task force published pediatric noninvasive car- diac imaging training guidelines in 2005

2015 American Heart Association

165. Adult Hodgkin Lymphoma Treatment (PDQ®): Health Professional Version

dehydrogenase, uric acid, and phosphorus. Radiographic examination. Computed tomography (CT) of the neck, chest, abdomen, and pelvis; or metabolic imaging (fluorine F 18-fludeoxyglucose positron emission tomography [PET]) with PET-CT. HIV testing. Hepatitis B and C serology. All stages of adult HL can be subclassified into A and B categories: B for those with defined general symptoms (described below) and A for those without B symptoms. The B designation is given to patients with any of the following (...) significant predictors of ischemic heart disease, congestive heart failure, arrhythmias, and vascular disease.[ ] In a cohort of 7,033 HL patients, MI mortality risk persisted for 25 years after first treatment with supradiaphragmatic radiation therapy (dependent on the details of treatment planning), doxorubicin, or vincristine.[ , ] The use of subcranial blocking did not reduce the incidence of fatal MI in a retrospective review, perhaps because of the exposure of the proximal coronary arteries

2018 PDQ - NCI's Comprehensive Cancer Database

166. Adult Non-Hodgkin Lymphoma Treatment (PDQ®): Health Professional Version

is similar to that of other low-grade lymphomas, especially diffuse, small lymphocytic lymphoma/chronic lymphocytic leukemia.[ , - ] If the viscosity relative to water is greater than four, the patient may have manifestations of hyperviscosity. Plasmapheresis is useful for temporary, acute symptoms (such as retinopathy, congestive heart failure, and central nervous system [CNS] dysfunction) but can be combined with chemotherapy for prolonged control of the disease. Symptomatic patients with a serum (...) with concomitant HCV infection, the majority attain a complete or partial remission after loss of detectable HCV RNA with treatment using interferon-alpha with or without ribavirin.[ ][ ] Mediterranean abdominal lymphoma The disease variously known as Mediterranean abdominal lymphoma, heavy–chain disease, or immunoproliferative small intestinal disease (IPSID), which occurs in young adults in eastern Mediterranean countries, is another version of MALT lymphoma, which responds to antibiotics in its early stages

2018 PDQ - NCI's Comprehensive Cancer Database

167. Imaging in the Diagnosis of Thoracic Outlet Syndrome

first rib anomalies [7], cervical ribs [24], congenital osseous malformations [25,26], and focal bone lesions [27]. Soft-tissue lesions, such as lung neoplasms [28], may also be evaluated, although the negative predictive value of chest radiography is debatable. Ultrasound US is widely used as a cost-effective, safe, and quick imaging modality in the initial evaluation of patients with either arterial or venous pathology throughout the body. Real-time duplex US is noninvasive and can be easily (...) or costoclavicular space. T1-weighted imaging performed in sagittal and axial planes can also demonstrate causative lesions of nTOS, including cervical ribs, congenital fibromuscular anomalies, and muscular hypertrophy (eg, subclavius muscle). Imaging with turbo- spin echo T2-weighted or short tau inversion recovery sequences can be useful in cases where spinal cord lesions or primary disorders of the brachial plexus (eg, brachial plexitis) are considered as alternative diagnoses to nTOS [43]. For noncontrast

2014 American College of Radiology

168. Task Force 7: Pediatric Cardiology Fellowship Training in Pulmonary Hypertension, Advanced Heart Failure, and Transplantation

• Interactions and relationships between the right and left ventricles in normal physiology and in the setting of pul- monary vascular diseases • Pathophysiology of congenital heart disease with intra- cardiac or arterial level shunt, including Eisenmenger physiology • Physiology of the patient with pulmonary artery hypertension (PAH) that is due to pulmonary venous hypertension 2.2.2.2. Clinical Evaluation, Imaging, and Hemodynamics • Identify the common presenting symptoms and physical examination findings (...) in patients with PH with and with- out congenital heart disease. • Identify the common presenting signs and symptoms of right and left heart failure. • Indications, risks, and benefits of techniques commonly used to evaluate patients with PH, including electrocardi- ography, echocardiography, cardiac magnetic resonance imaging, cardiac computed tomography, ventilation, and perfusion lung scans • Indications, risks, and benefits of cardiac catheterization and vasodilator testing 2.2.2.3. Classification

2015 American Heart Association

169. A consensus document for the selection of lung transplant candidates: 2014 - An update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation

that this document is a consensus document rather than a guideline, grading of levels of evidence and recommendations was not undertaken. Instead, as noted previously, a comprehensive literature search and consensus expert opinion have been presented. In all instances, the Writing Committee adhered to the ISHLT Standards and Guidelines Document Development Protocol (update January 2013). General candidacy consid era tions Lung transplantation should be considered for adults with chronic, end-stage lung disease (...) and mortality, it is important to consider the overall sum of contraindications and comorbidities. The following lists are not intended to include all possible clinical scenarios but rather to highlight common areas of concern. Absolute contraindication s • Lung transplantation should not be offered to adults with a recent history of malignancy. A 2-year disease-free interval combined with a low predicted risk of recurrence after lung transplantation may be reasonable, for instance, in non-melanoma

2015 International Society for Heart and Lung Transplantation

170. SCAI/HFSA Clinical Expert Consensus Document on the Use of Invasive Hemodynamics for the Diagnosis and Management of Cardiovascular Disease

interpreting accurate hemodynamic data obtained in the cardiac catheterization laboratory. Valvular Heart Disease For patients with valvular heart disease, an invasive hemodynamic evaluation is recommended to resolve discrepancies between clinical findings and noninvasive imaging data when surgical or catheter‐based therapy is being considered. When a patient undergoes an invasive hemodynamic evaluation for valvular disease, a simultaneous study of multiple central cardiac chamber hemodynamics should (...) . Attention should be directed toward the relative rise in left and right atrial pressure (RAP) with exercise, because the ratio of RAP/PCWP with exercise can be highly informative in isolating which “side” of the heart and circulation is the predominantly diseased and has the least physiologic reserve. Congenital Heart Disease For most patients with shunt lesions, echocardiography performed by an experienced sonographer, with careful examination of the gradients and chamber morphology, is sufficient

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2017 Society for Cardiovascular Angiography and Interventions

171. AIM Clinical Appropriateness Guidelines for Genetic Testing for Hereditary Cardiac Disease

of symptoms. Dilated Cardiomyopathy Dilated cardiomyopathy (DCM) is characterized by enlargement of the left ventricle of the heart and systolic impairment, in the absence of abnormal loading conditions or coronary artery disease sufficient to cause global systolic dysfunction (Haas 2015). The symptoms of DCM are similar to heart failure including shortness of breath, chest pain/tightness, fainting episodes and cardiac arrhythmias. The most serious complication of DCM is sudden, irregular heart rhythms (...) cardiac conduction disease (i.e. first, second or third degree heart block) and/or family history of premature unexplained death. In addition, they state that genetic testing can be useful for patients with familial DCM to confirm diagnosis, to recognize those who are at highest risk of arrhythmia and syndromic PROPRIETARY Guidelines developed by, and used with permission from, Informed Medical Decisions, Inc. © 2017 Informed Medical Decisions, Inc. All Rights Reserved. 7 features, to facilitate

2017 AIM Specialty Health

172. Elevated non-invasive liver fibrosis markers and risk of liver carcinoma in adult patients after repair of tetralogy of Fallot. (PubMed)

Elevated non-invasive liver fibrosis markers and risk of liver carcinoma in adult patients after repair of tetralogy of Fallot. Congestive hepatopathy and hepatocellular carcinoma is a serious complication after Fontan procedure. Liver fibrosis due to hepatic congestion could occur also in adult patients after repair of tetralogy of Fallot (rTOF). However, the incidence and severity remain unclear.A total of 111 patients with adult congenital heart disease between 2009 and 2016 were enrolled (...) pathological evidence of moderate and severe (F2 and F3) liver fibrosis and one had combined hepatocellular and cholangiocarcinoma.We first demonstrated elevated liver fibrosis markers in adult patients with rTOF. These levels may help to predict the progressive liver disease as well as consider the timing of pulmonary valve replacement.Copyright © 2019 Elsevier B.V. All rights reserved.

2019 International journal of cardiology

173. Dual-Source Computed Tomography Evaluation of Children with Congenital Pulmonary Valve Stenosis (PubMed)

Dual-Source Computed Tomography Evaluation of Children with Congenital Pulmonary Valve Stenosis Despite dual-source computed tomography (DSCT) technology has been performed well on adults or infants with heart disease, specific knowledge about children with congenital pulmonary valve stenosis (PS) remained to be established.This original research aimed to establish a professional approach of DSCT performing technology on children and to assess the image quality performed by DSCT to establish (...) a diagnostic evaluation for children with PS.Ninety-eight children with congenital PS referred to affiliated hospital of Jining medical college were recruited from October 2013 to March 2015. Participants were divided into four groups according to different ages (0 - 1, 1 - 3, 3 - 7, 7 - 14), or three groups according to different heart rates (< 90, 90 - 110, > 110). Image quality of pulmonary valves was assessed based on a four-point grading scale (1 - 4 points). Those cases achieving a score of ≥ 3

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2016 Iranian Journal of Radiology

174. Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging

: Diagnostic Official Title: An Adaptive, Open-Label Study to Evaluate the Biodistribution of 89Zirconium-labelled GSK2398852 in the Heart and Other Organs of Patients With Transthyretin Cardiomyopathy (ATTR-CM) Using Positron Emission Tomography (PET) Imaging Actual Study Start Date : April 6, 2018 Actual Primary Completion Date : July 20, 2018 Actual Study Completion Date : July 20, 2018 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go (...) as solution containing 10 mg 89Zr-GSK2398852 for Infusion. Subjects will be administered 37 (Megabecquerel) MBq radioactive dose of 89Zr-GSK2398852 by the IV route at each dosing session. Outcome Measures Go to Primary Outcome Measures : Standardized Uptake Values (SUV) in focal anatomical regions of the heart following 80-200 milligrams (mg) dose of anti-SAP mAb [ Time Frame: Up to Day 6 ] PET images will be visually reviewed to assess the radioactivity distribution. SUV is the measured radioactivity

2018 Clinical Trials

175. Early Diagnosis of Sickle Acute Chest Syndrome Using a Combination of Plasma Bimarkers and Chest Imaging

Posted : March 26, 2019 Sponsor: National Heart, Lung, and Blood Institute (NHLBI) Information provided by (Responsible Party): National Institutes of Health Clinical Center (CC) ( National Heart, Lung, and Blood Institute (NHLBI) ) Study Details Study Description Go to Brief Summary: Background: Painful vasoocclusive crisis (VOC) occurs in people with sickle cell disease (SCD). People with VOC have many visits to the hospital. About 10 30 percent of these people will go on to develop acute chest (...) Sickle Cell Disease Acute Chest Syndrome Pulmonary Syndrome Pneumonia Additional relevant MeSH terms: Layout table for MeSH terms Syndrome Anemia, Sickle Cell Acute Chest Syndrome Disease Pathologic Processes Anemia, Hemolytic, Congenital Anemia, Hemolytic Anemia Hematologic Diseases Hemoglobinopathies Genetic Diseases, Inborn Lung Diseases Respiratory Tract Diseases Respiration Disorders

2018 Clinical Trials

176. Imaging by 4 DFlow in Patients With Tetralogy of Fallot

Flow CMR for the assessment of these parameters (ventricular volume, ventricular systolic function, and regurgitation of the pulmonary pathway). Condition or disease Intervention/treatment Phase Congenital Heart Disease Procedure: magnetic resonance imaging Not Applicable Detailed Description: Congenital heart disease, or corrected heart disease requires regular, specialized follow-up throughout the life of these patients. Among the recommended examinations, cardiac MRI is the reference (...) Chirurgical Marie Lannelongue: Congenital heart disease Tetralogy of Fallot Imaging by 4D Flow, Magnetic resonance imaging Prevention of ventricular dysfunction Additional relevant MeSH terms: Layout table for MeSH terms Heart Diseases Heart Defects, Congenital Tetralogy of Fallot Cardiovascular Diseases Cardiovascular Abnormalities Congenital Abnormalities

2018 Clinical Trials

177. Procedure Sedation With Dexmedetomidine in Children With Autism Spectrum Disorders During Magnetic Resonance Imaging

or hypersensitive reaction to dexmedetomidine Organ dysfunction, and significant developmental delays or behavior problems Cardiac arrhythmia Known. acyanotic congenital heart disease or children after cardiac interventional procedures for follow-up examination Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study (...) Procedure Sedation With Dexmedetomidine in Children With Autism Spectrum Disorders During Magnetic Resonance Imaging Procedure Sedation With Dexmedetomidine in Children With Autism Spectrum Disorders During Magnetic Resonance Imaging - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2018 Clinical Trials

178. Interactive Guided Ultrasound Examinations Done by Non-experts of Ultrasound Imaging

informed consent. All volunteers should be affiliated to the French Social Security. All volunteers will be scheduled for a routine transthoracic echocardiography exam in the echocardiography laboratory at the investigation site as part of standard care. Exclusion Criteria: Subjects with congenital heart diseases (except bicuspid aortic valve) Pregnant women Adults lacking decisional capacity Adults placed under a legal protection regime (guardianship, curatorship, judicial protection) Adults (...) Healthcare Information provided by (Responsible Party): Philips Healthcare Study Details Study Description Go to Brief Summary: This prospective study is a pilot study for evaluating a guidance system that aims to facilitate high-quality echocardiographic acquisitions. Condition or disease Intervention/treatment Phase Cardiac Disease Heart Failure Cardiac Ischemia Device: TransThoracic Echocardiography imaging Not Applicable Detailed Description: The primary objective of this study is to assess

2018 Clinical Trials

179. Image-based Multi-scale Modeling Framework of the Cardiopulmonary System: Longitudinal Calibration and Assessment of Therapies in Pediatric Pulmonary Hypertension

to develop a multi-scale computational model of Pulmonary Hypertension, this clinical model will be calibrated using longitudinal, retrospectively and prospectively acquired human clinical data. Condition or disease Intervention/treatment Pulmonary Hypertension Congenital Heart Disease Pediatric Congenital Heart Disease Procedure: cardiac catheterization Radiation: Cardiac MRI Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 50 participants (...) and Vascular Surgery, University of Michigan ClinicalTrials.gov Identifier: Other Study ID Numbers: HUM00117706 First Posted: June 21, 2018 Last Update Posted: June 21, 2018 Last Verified: June 2018 Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Hypertension Heart Diseases Hypertension, Pulmonary Heart Defects, Congenital Vascular Diseases Cardiovascular

2018 Clinical Trials

180. Management of Heart Failure  (3rd Edition)

% Fraction (HFpEF)17 4. Aetiology Heart failure is not a complete diagnosis. It is important to identify the underlying disease and the precipitating cause(s), if present. Although systolic and diastolic dysfunction are separate pathophysiological entities, they often share common aetiologies. The most common underlying causes of HF in adults are: • Coronary artery disease • Hypertension Slightly less common causes include: • Dilated cardiomyopathy-idiopathic, familial • Valvular heart disease • Diabetic (...) cardiomyopathy Other causes of HF include: • Congenital heart disease • Cor pulmonale • Pericardial disease: constrictive pericarditis, cardiac tamponade • Hypertrophic cardiomyopathy • Viral myocarditis • Acute rheumatic fever • Toxic: Alcohol, adriamycin, cyclophosphamide • Endocrine and metabolic disorders: thyroid disease, acromegaly, phaechromocytoma • Collagen vascular disease: systemic lupus erythematosis, polymyositis, polyarteritis nodosa • Tachycardia induced cardiomyopathy • Miscellaneous - severe

2014 Ministry of Health, Malaysia

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