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Congenital Heart Disease Imaging in Adults

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101. Magnetic Resonance Myocardial Perfusion Imaging: Safety and Indications in Pediatrics and Young Adults. (Abstract)

, exercise-induced stress MPI, and MPI for cardiac mass diagnosis. Relevant clinical history, exam indications, and adverse reactions following gadolinium-based contrast agent and adenosine administration were recorded. Studies were reviewed for the presence of myocardial perfusion defects, wall motion abnormalities, and delayed myocardial enhancement. The most common indications from MPI were congenital heart disease (CHD), Kawasaki disease, anomalous coronary artery, or myocardial mass characterization (...) Magnetic Resonance Myocardial Perfusion Imaging: Safety and Indications in Pediatrics and Young Adults. The purpose of this study was to assess the safety and indications for cardiac magnetic resonance (CMR) with myocardial perfusion imaging (MPI) in a cohort of children and young adults. A retrospective review of 178 children and young adults who underwent CMR with MPI was performed. Studies were categorized based on study protocols as MPI with resting perfusion only, adenosine stress MPI

2017 Pediatric Cardiology

102. Management of Rhinosinusitis in Adolescents and Adults

. 1, level III Smoking (active and passive), family history of chronic rhinosinusitis, asthma and gastroesophageal reflux disease are important risk factors for rhinosinusitis.Management of Rhinosinusitis in Adolescents and Adults 3 4. DIAGNOSIS The diagnosis of RS is usually based on clinical symptoms supported by diagnostic imaging or nasal endoscopy. 1, level III 4.1 Clinical Diagnosis • Clinical definition of rhinosinusitis in adults is defined as: ? Inflammation of the nose and the paranasal (...) of Rhinosinusitis in Adolescents and Adults 19 ABRS is unproven. 19, level III In local context, decongestants is prescribed in ARS. • Topical decongestants should not be prescribed for more than two weeks due to rebound phenomenon. Oral decongestants should be cautiously prescribed in those with medical conditions such as diabetes mellitus, cardiovascular diseases, glaucoma and benign prostate hyperplasia. c. Mucolytics There is no evidence to support the use of mucolytics in RS. 1, level III d. Antiviral

2019 Ministry of Health, Malaysia

103. BTS Guideline for Bronchiectasis in adults

erythematosus, and ankylosing spondylitis. A study of a 507 patient cohort with primary Sjogren’s syndrome (PSS) identified 120 patients with suspected pulmo- nary disease, and found bronchiectasis on CT scan in 50 patients. 41 Retrospective studies confirm the association. 42–44 A retrospective review of 79 patients with Marfan’s who underwent HRCT imaging found evidence of bronchiectasis in 28%. 45 Airway dilatation was described as not severe, often confined to one lobe and was said to localise (...) of cough in adults 61 ). SeCTion 6 investigations for causes of bronchiectasis Introduction Single centre studies have shown that investigations into the underlying cause of bronchiectasis can change patient manage- ment in a significant proportion of cases (5%–37%) and identify previously unrecognised conditions such as allergic broncho- pulmonary aspergillosis (ABPA), primary antibody deficiency syndromes and cystic fibrosis (CF) which have important ther- apeutic and prognostic implications. 23 62

2019 British Thoracic Society

104. Adult and Pediatric Antibiotic Prophylaxis during Vascular and IR Procedures: A Society of Interventional Radiology Practice Parameter Update Endorsed by the Cardiovascular and Interventional Radological Society of Europe and the Canadian Association for

in 2015 (37– 39) indicate that prophylaxis against a-hemolytic streptococci (Streptococcus viridans) is indicated only for patients at high risk, including those with prosthetic valves, a history of infective endocarditis, congenital heart disease repaired with foreign material, or cardiac transplant with valvulopathy. In thesepatients,antibioticagentsarerecommendedbeforelungorchestbiopsy or abscess/empyema drainage (37). Amoxicillin or cefazolin are effective agents, with clindamycin (...) are prescribed based on the patient’s age, weight, body surface area, and/or clinical condition (21). For pediatric antibiotic regimens, doses are usually weight-based, and therefore careful calculation is required to ensure correct dosage. Pediatric patients therefore are at a higher risk than adults for experiencing the effects of dosing errors; this may result in subtherapeutic antibiotic dosing causing treatment failure and the emergence of resistant organisms (22) or supratherapeutic dosing and toxicity

2019 Society of Interventional Radiology

105. Imaging Program Guidelines: Pediatric Imaging

or hereditary Examples include ataxia-telangiectasia, fragile X syndrome, congenital anomalies of the posterior fossa. Congenital or developmental anomaly Diagnosis or management (including perioperative evaluation) of a suspected or known congenital anomaly or developmental condition Examples include Chiari malformation, craniosynostosis, macrocephaly, and microcephaly. ? Ultrasound is required as the initial study to evaluate macrocephaly in patients under 5 months of age. Magnetic Resonance Imaging (MRI (...) and/or standards of medical practice. These include: ¾ Oncologic imaging – Considerations include the type of malignancy and the point along the care continuum at which imaging is requested ¾ Conditions which span multiple anatomic regions – Examples include certain gastrointestinal indications or congenital spinal anomalies Repeated Imaging In general, repeated imaging of the same anatomic area should be limited to evaluation following an intervention, or when there is a change in clinical status

2017 AIM Specialty Health

106. Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency Full Text available with Trip Pro

metabolic syndrome and related sequelae. (2|⊕○○○) 6.11 In adult patients with congenital adrenal hyperplasia, we suggest screening of bone mineral density in anyone subjected to a prolonged period of higher-than-average glucocorticoid dosing, or who has suffered a nontraumatic fracture. (2|⊕○○○) 6.12 In adults with classic congenital adrenal hyperplasia, we recommend against routine adrenal imaging. (1|⊕○○○) Technical remark: Reserve adrenal imaging for individuals with classic congenital adrenal (...) with congenital adrenal hyperplasia, we recommend educating patients and their guardians and close contacts on adrenal crisis prevention and increasing the dose of glucocorticoid (but not mineralocorticoid) during intercurrent illness. (1|⊕⊕⊕○) 4.11 We recommend equipping every patient with congenital adrenal hyperplasia with a glucocorticoid injection kit for emergency use and providing education on parenteral self-administration (young adult and older) or lay administration (parent or guardian) of emergency

2018 Pediatric Endocrine Society

107. Interventional cardiology in adults with congenital heart disease. (Abstract)

Interventional cardiology in adults with congenital heart disease. Interventional cardiac catheterization has become an integral component of the management of adults with congenital heart disease. The origins of this approach come from the paediatric interventional experience, although techniques and indications for interventional cardiac catheterization in adults are now being developed for use in the burgeoning field of adult congenital heart disease. Progress in the application (...) and acceptance of interventional cardiac catheterization in this setting has been swift, and the pace is quickening. This Review provides a broad overview of some of the most common procedures used in the treatment of adults with congenital heart lesions, with an emphasis on new tools that have revolutionized the field. Specifically, we discuss interventions that can be broadly classified into the following groups: techniques for closing shunt lesions, valvular interventions, methods for achieving patency

2013 Nature reviews. Cardiology

108. Integration of Computed Tomography and Three-Dimensional Echocardiography for Hybrid Three-Dimensional Printing in Congenital Heart Disease Full Text available with Trip Pro

Integration of Computed Tomography and Three-Dimensional Echocardiography for Hybrid Three-Dimensional Printing in Congenital Heart Disease Three-dimensional (3D) printing is an emerging technology aiding diagnostics, education, and interventional, and surgical planning in congenital heart disease (CHD). Three-dimensional printing has been derived from computed tomography, cardiac magnetic resonance, and 3D echocardiography. However, individually the imaging modalities may not provide adequate (...) visualization of complex CHD. The integration of the strengths of two or more imaging modalities has the potential to enhance visualization of cardiac pathomorphology. We describe the feasibility of hybrid 3D printing from two imaging modalities in a patient with congenitally corrected transposition of the great arteries (L-TGA). Hybrid 3D printing may be useful as an additional tool for cardiologists and cardiothoracic surgeons in planning interventions in children and adults with CHD.

2016 Journal of Digital Imaging

109. The Life Experience of Young Women (Age 18-38) Who Live With Congenital Heart Disease

, 2014; Hickey et al., 2012). Most qualitative studies focusing on the quality of life compare men and women, completely ignoring women's body image and the experience of womanhood (Hickey et al., 2012; Hövels-Gürich et al., 2007; Sarikouch, et al., 2013). This study aims to focus on women's stories about their life experiences and the influence of surgery(ies) on their daily life using an the qualitative phenomenological approach. Condition or disease Intervention/treatment Women With Congenital (...) The Life Experience of Young Women (Age 18-38) Who Live With Congenital Heart Disease The Life Experience of Young Women (Age 18-38) Who Live With Congenital Heart Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2016 Clinical Trials

110. The Application Value of STIC in the Diagnosis of Fetal Complex Congenital Heart Disease

counseling. Condition or disease Congenital Heart Disease Detailed Description: This is a diagnostic test in Shanghai Xinhua hospital from Nov.2016 to Dec.2017. 265 Cases are gravidas with fetal congenital heart disease diagnosed by echocardiography.Only gravidas who are willing to have complete pregnancy checks and finally delivery or abortion in the hospital are interviewed are eligible for the study. Study participants will be asked for their informed consent.We collect their fetal 2D echocardiography (...) and STIC images every 4-6 weeks during pregnancy and 1 weeks after the baby giving birth we finish their neonatal echocardiography. Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 265 participants Observational Model: Case-Only Time Perspective: Prospective Official Title: The Application Value of STIC in the Diagnosis of Fetal Complex Congenital Heart Disease Actual Study Start Date : April 25, 2017 Estimated Primary Completion Date : December

2016 Clinical Trials

111. Assessing Neurodevelopment in Congenital Heart Disease.

. Children with CHD are a known risk population for brain injury, with neurodevelopmental alterations shown over time in up to 50% of cases. No adequate description exists of the type of neurocognitive anomalies or risk factors associated with CHD, and consequently no prognostic markers that may allow identification of high-risk cases are available. Condition or disease Intervention/treatment Phase Congenital Heart Disease Procedure: Sonography Device: Magnetic Resonance Imaging Other: Bailey Test (...) or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: Child, Adult, Older Adult Sexes Eligible for Study: Female Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria: Single pregnancies Major Congenital Heart Disease Informed Consent Signed Exclusion Criteria: Major extra-cardiac malformations

2016 Clinical Trials

112. Study of RV Remodeling in Congenital Heart Disease

in repaired TOF patients, PS patients with sex and age-matched controls 2, Assess the relationship of our proposed parameters to global RV function and exercise capacity in repaired TOF patients and PS patient Condition or disease Intervention/treatment Congenital Heart Disease Other: Cardiovascular Magnetic Resonance Imagine (MRI) Other: Cardiopulmonary exercise testing (CPET) Other: Echocardiography Detailed Description: Right ventricular (RV) function is increasingly recognized to play an important (...) Study of RV Remodeling in Congenital Heart Disease Study of RV Remodeling in Congenital Heart Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study of RV Remodeling in Congenital Heart Disease

2016 Clinical Trials

113. Evaluation of Impedance Cardiography for Measurement of Stroke Volume in Congenital Heart Disease. (Abstract)

Evaluation of Impedance Cardiography for Measurement of Stroke Volume in Congenital Heart Disease. Noninvasive measurement of cardiac output (CO) and particularly stroke volume (SV) remain difficult but potentially valuable. These variables can be particularly challenging to measure in children with congenital heart disease (CHD). Impedance cardiography (IC) is a technique shown to be accurate in measuring SV in adults and in children with structurally normal hearts. The ease of use (...) and rapidity of SV measurement using IC makes it potentially attractive for young patients with CHD. Advances in IC technology have led to more sophisticated signal-morphology IC (SMIC) devices that may further improve accuracy. We tested the accuracy of SMIC to measure SV in 21 subjects with CHD by comparing measurements with those from cardiac magnetic resonance (CMR) imaging. There was good agreement between SMIC and CMR in measurement of SV: mean difference = 1.7 ml (p = 0.47); r = 0.89. The agreement

2016 Pediatric Cardiology

114. Grown-Up Congenital Heart Disease

considerations . . . . . . . . . . . . . . . . . . . . . . . . . .2918 3.1 Prevalence of grown-up congenital heart disease and organization of care . . . . . . . . . . . . . . . . . . . . . . . . .2918 3.2 Diagnostic work-up . . . . . . . . . . . . . . . . . . . . . . . . .2918 3.2.1 Echocardiography . . . . . . . . . . . . . . . . . . . . . . . .2919 3.2.2 Cardiac magnetic resonance imaging . . . . . . . . . . . .2919 3.2.3 Computed tomography . . . . . . . . . . . . . . . . . . . . .2920 3.2.4 (...) valve area AVSD atrioventricular septal defect BAV bicuspid aortic valve BNP B-type natriuretic peptide BSA body surface area CAD coronary artery disease ccTGA congenitally corrected transposition of the great arteries CHD congenital heart disease CMR cardiac magnetic resonance CoA coarctation of the aorta CPET cardiopulmonary exercise testing CRT cardiac resynchronization therapy CT computed tomography DCRV double-chambered right ventricle ECG electrocardiogram EF ejection fraction EP

2010 European Society of Cardiology

115. Guidelines for the Appropriate Use of Bedside General and Cardiac Ultrasonography in the Evaluation of Critically Ill Patients Full Text available with Trip Pro

) infarct (1C), the efficacy of fluid resuscitation (1C) and inotropic therapy (2C), presence of RV dysfunction (2C) in septic shock, the reason for cardiac arrest to assist in cardiopulmonary resuscitation (1B–2C depending on rhythm), status in acute coronary syndromes (ACS) (1C), the presence of pericardial effusion (1C), cardiac tamponade (1B), valvular dysfunction (1C), endocarditis in native (2C) or mechanical valves (1B), great vessel disease and injury (2C), penetrating chest trauma (1C (...) of technologies including pulse contour analysis ( ), transpulmonary thermodilution ( ), and bioreactance ( ) have shown promise in evaluation of critically ill patients, bedside cardiac ultrasound (BCU) is an established technique to evaluate cardiac function. BCU evaluation in the ICU is undertaken by a healthcare provider who serves as both the operator performing the study and the interpreter of the images captured in the context of their clinical significance. The purpose of the ultrasound evaluation

2016 Society of Critical Care Medicine

116. Chronic Chest Pain - High Probability of Coronary Artery Disease

study for evaluation of the effect of image optimization with contrast on the diagnostic accuracy of dobutamine echocardiography in coronary artery disease The OPTIMIZE Trial. JACC Cardiovasc Imaging. 2008;1(2):145-152. 41. Al Sayari S, Kopp S, Bremerich J. Stress cardiac MR imaging: the role of stress functional assessment and perfusion imaging in the evaluation of ischemic heart disease. Radiol Clin North Am. 2015;53(2):355-367. 42. al-Saadi N, Gross M, Paetsch I, et al. Dobutamine induced (...) - SPECT and coronary angiography. J Magn Reson Imaging. 2000;11(6):607-615. 47. Kwong RY, Schussheim AE, Rekhraj S, et al. Detecting acute coronary syndrome in the emergency department with cardiac magnetic resonance imaging. Circulation. 2003;107(4):531-537. ACR Appropriateness Criteria ® 10 Chronic Chest Pain—High Probability of CAD 48. Nagel E, Klein C, Paetsch I, et al. Magnetic resonance perfusion measurements for the noninvasive detection of coronary artery disease. Circulation. 2003;108(4):432

2016 American College of Radiology

117. 2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Gui Full Text available with Trip Pro

with prior SCA, sustained VT, or syncope caused by VA. Structural heart disease This term encompasses IHD, all types of cardiomyopathy, valvular heart disease, and adult congenital heart disease. Cardiac channelopathy Arrhythmogenic disease due to a genetic abnormality that results in dysfunction of a cardiac ion channel (eg, long QT syndrome, catecholaminergic polymorphic VT). *The definition of this term may differ across publications. Refer to the entry for the definition used in this document. AV (...) -effectiveness ratio; QALY, quality-adjusted life-years; and WHO-CHOICE, World Health Organization Choosing Interventions that are Cost-Effective. Reproduced from Anderson, et al. 1.2. Organization of the Writing Committee The writing committee consisted of cardiac electrophysiologists (including those specialized in pediatrics), general adult and pediatric cardiologists (including those specialized in critical care and acute coronary syndromes [ACS], genetic cardiology, heart failure, and cost-effectiveness

2017 American Heart Association

118. 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society Full Text available with Trip Pro

, structural heart disease, previous arrhythmias, or reduced ventricular function Brief prodrome, such as palpitations, or sudden loss of consciousness without prodrome Syncope during exertion Syncope in the supine position Low number of syncope episodes (1 or 2) Abnormal cardiac examination Family history of inheritable conditions or premature SCD (<50 y of age) Presence of known congenital heart disease More Often Associated with Noncardiac Causes of Syncope Younger age No known cardiac disease Syncope (...) : Recommendation e38 5.3. Carotid Sinus Syndrome: Recommendations e38 5.4. Other Reflex Conditions e38 6. Orthostatic Hypotension: Recommendations e38 6.1. Neurogenic Orthostatic Hypotension: Recommendations e38 6.2. Dehydration and Drugs: Recommendations e39 7. Orthostatic Intolerance e39 8. Pseudosyncope: Recommendations e40 9. Uncommon Conditions Associated with Syncope e40 10. Age, Lifestyle, and Special Populations: Recommendations e40 10.1. Pediatric Syncope: Recommendations e40 10.2. Adult Congenital

2017 American Heart Association

119. 2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Hea Full Text available with Trip Pro

. In addition, a trend over time has suggested that out-of-hospital cardiac arrest patients who are admitted alive to a hospital are becoming more likely to have high-risk clinical profiles, as opposed to manifest disease. The younger population—children, adolescents, and young adults—is affected by a series of disorders that manifest earlier in life, including the genetic structural disorders and cardiac channelopathies, myocarditis, congenital heart disease, and other rare disorders. During the transition (...) al. 1.2. Organization of the Writing Committee The writing committee consisted of cardiac electrophysiologists (including those specialized in pediatrics), general adult and pediatric cardiologists (including those specialized in critical care and acute coronary syndromes [ACS], genetic cardiology, heart failure, and cost-effectiveness analyses), a geriatrician with expertise in terminal care and shared decision-making, and a lay representative, in addition to representatives from the ACC, AHA

2017 American Heart Association

120. European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults Full Text available with Trip Pro

. (ii) We recommend that every patient with (suspected) ACC should undergo careful clinical assessment, detailed endocrine work-up to identify autonomous hormone excess and adrenal-focused imaging. (iii) We recommend that adrenal surgery for (suspected) ACC should be performed only by surgeons experienced in adrenal and oncological surgery aiming at a complete en bloc resection (including resection of oligo-metastatic disease). (iv) We suggest that all suspected ACC should be reviewed by an expert (...) into account when assessing the prognosis and treatment options: tumor stage, resection status, Ki67 index (or mitotic count), autonomous cortisol secretion and the patient’s general condition (++OO). R.5.3. During follow-up, we recommend re-assessing prognosis at each evaluation, to guide treatment strategy (++OO). 1.6. Methods and time interval for imaging and hormonal assessment during follow-up R.6.1. We recommend following patients with regular cross-sectional imaging of the abdomen, pelvis and chest

2018 European Society of Endocrinology

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