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Congenital Heart Disease Imaging in Adults

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4421. Beta-blockade does not alter plasma cytokine concentrations and ventricular function in young adults with right ventricular dysfunction secondary to operated congenital heart disease. (Abstract)

Beta-blockade does not alter plasma cytokine concentrations and ventricular function in young adults with right ventricular dysfunction secondary to operated congenital heart disease. Right heart failure is a major problem of young adults with congenital heart disease (ACHD) that has been corrected by cardiac surgery. In left ventricular dysfunction (LVD), beta-blocker therapy improved cytokine concentrations and clinical status. Thus, the effect of bisoprolol on clinical status and plasma (...) cytokine concentrations in ACHD patients with right heart failure after surgical correction for Tetralogy of Fallot was investigated.A prospective, randomized, double-blind, placebo controlled study for a duration of 6 months was carried out. A total of 34 patients (30.9+/-9.5 years; New York Heart Association I or II) with brain natriuretic peptide plasma concentrations >100 pg/ml and peak oxygen uptake <25 ml . kg(-1) .min(-1) were recruited. Bisoprolol did not reduce plasma concentrations of soluble

2008 Circulation journal : official journal of the Japanese Circulation Society Controlled trial quality: uncertain

4422. Juvenile and adult congenital heart disease: time-resolved 3D contrast-enhanced MR angiography. (Abstract)

Juvenile and adult congenital heart disease: time-resolved 3D contrast-enhanced MR angiography. To assess the incremental diagnostic value of time-resolved three-dimensional (3D) magnetic resonance (MR) angiography over single-phase 3D MR angiography and cine MR imaging in juvenile and adult patients with congenital heart disease (CHD).The study was HIPAA compliant and was approved by the institutional review board. Written informed consent was obtained from each patient. Eighty-one consecutive (...) patients (46 male and 35 female patients; mean age, 31.1 years +/- 13.5 [standard deviation]) with CHD were examined with a 1.5-T MR imaging unit. The imaging protocol comprised time-resolved MR angiography (repetition time msec/echo time msec, 2.01/0.81) after injection of 0.03 mmol gadodiamide per kilogram of body weight at 4 mL/sec and single-phase high-spatial-resolution MR angiography (2.87/0.97) after injection of 0.15 mmol/kg gadodiamide at 1.5 mL/sec. After review of the time-resolved

2007 Radiology

4423. Relation of brain natriuretic peptide to myocardial performance index in adults with congenital heart disease. (Abstract)

) is a predictor of systolic and diastolic dysfunction in anatomically correct hearts. The correlation of BNP to MPI in patients with congenital heart disease was determined. Fifty-four adults with congenital heart disease were evaluated. BNP was measured using standardized assays. Doppler echocardiography was performed within 6 months of BNP assay. There were no changes in clinical status during this interval. An experienced observer was blinded and evaluated all echocardiographic images, and MPI and ejection (...) Relation of brain natriuretic peptide to myocardial performance index in adults with congenital heart disease. Myocardial performance index (MPI) is an echocardiographic Doppler-derived measure of ventricular function previously validated in patients with congenital heart disease. It may be preferred over conventional noninvasive measures of ventricular function in patients with complex anatomy because it is dependent on neither geometric shape nor heart rate. Brain natriuretic peptide (BNP

2007 American Journal of Cardiology

4424. Biopsychosocial experiences of adults with congenital heart disease: review of the literature. (Abstract)

Biopsychosocial experiences of adults with congenital heart disease: review of the literature. Approximately 1% of all newborns display some form of congenital heart disease (CHD). Successful medical and surgical management of CHD has allowed 85% of these children to survive into adulthood and produced a new set of challenges for both patients and doctors with an emphasis on quality of life and psychosocial functioning.The current paper has 3 aims: (1) to summarize the research literature (...) measures. Similar European studies have generally not demonstrated such differences. Additional research suggests that areas of functioning that may be particularly affected include neurocognitive functioning, body image, social and peer relationships, and mild delays in developmental functioning.These studies suggest that patients with CHD are successfully engaging in full adult responsibilities and roles but do experience specific psychosocial challenges that may impact emotional functioning, self

2005 American Heart Journal

4425. Stratification of pediatric heart failure on the basis of neurohormonal and cardiac autonomic nervous activities in patients with congenital heart disease. Full Text available with Trip Pro

Stratification of pediatric heart failure on the basis of neurohormonal and cardiac autonomic nervous activities in patients with congenital heart disease. Stratification of pediatric patients with congenital heart disease (CHD) has been based on their hemodynamics and/or functional capacity. Our purpose was to compare cardiac autonomic nervous activity (CANA) and neurohormonal activities (NHA) with postoperative status in stable CHD patients with biventricular physiology.We divided 379 (...) subjects (297 CHD patients, 28 dilated cardiomyopathy patient, and 54 control subjects) into 4 subgroups according to New York Heart Association (NYHA) class (1.3+/-0.7) and measured various CANA and NHA indices. Stepwise decreases in baroreflex sensitivity (BRS), heart rate variability (HRV), adrenergic imaging, and vital capacity (VC) were observed in proportion to functional capacity in normal to NYHA II patients (P<0.001). However, there were no differences in these indices between NYHA II and III

2003 Circulation

4426. Report of the National Heart, Lung, and Blood Institute Working Group on research in adult congenital heart disease. Full Text available with Trip Pro

and catheter-based interventions, management of related conditions including pregnancy and arrhythmias, quality of life, and informatics. After research and training barriers were discussed, the Working Group recommended outreach and educational programs for adults with congenital heart disease, a network of specialized adult congenital heart disease regional centers, technology development to support advances in imaging and modeling of abnormal structure and function, and a consensus on appropriate (...) Report of the National Heart, Lung, and Blood Institute Working Group on research in adult congenital heart disease. The Working Group on research in adult congenital heart disease (ACHD) was convened in September 2004 under the sponsorship of National Heart, Lung, and Blood Institute (NHLBI) and the Office of Rare Diseases, National Institutes of Health, Department of Health and Human Services, to make recommendations on research needs. The purpose of the Working Group was to advise the NHLBI

2006 Journal of the American College of Cardiology

4427. Cardiac catheterisation guided by MRI in children and adults with congenital heart disease. (Abstract)

Cardiac catheterisation guided by MRI in children and adults with congenital heart disease. Fluoroscopically guided cardiac catheterisation is an essential tool for diagnosis and treatment of congenital heart disease. Drawbacks include poor soft tissue visualisation and exposure to radiation. We describe the first 16 cases of a novel method of cardiac catheterisation guided by MRI with radiographic support.In our cardiac catheterisation laboratory, we combine magnetic resonance and radiographic (...) setting, allows better soft tissue visualisation, provides more pertinent physiological information, and results in lower radiation exposure than do fluoroscopically guided procedures. MRI guidance could become the method of choice for diagnostic cardiac catheterisation in patients with congenital heart disease, and an important tool in interventional cardiac catheterisation and radiofrequency ablation.

2003 Lancet

4428. Magnetic resonance imaging of the brain and haematological profile in adult cyanotic congenital heart disease without stroke Full Text available with Trip Pro

Magnetic resonance imaging of the brain and haematological profile in adult cyanotic congenital heart disease without stroke 16415201 2006 02 06 2018 11 13 1468-201X 92 2 2006 Feb Heart (British Cardiac Society) Heart Magnetic resonance imaging of the brain and haematological profile in adult cyanotic congenital heart disease without stroke. 263-5 Horigome H H Iwasaki N N Anno I I Kurachi S S Kurachi K K eng Letter England Heart 9602087 1355-6037 0 Protein C AIM IM Adolescent Adult (...) Cerebrovascular Disorders diagnosis etiology physiopathology Female Heart Defects, Congenital complications pathology physiopathology Hematocrit Humans Magnetic Resonance Angiography Male Middle Aged Protein C analysis 2006 1 18 9 0 2006 2 7 9 0 2006 1 18 9 0 ppublish 16415201 92/2/263 10.1136/hrt.2004.059287 PMC1860780 Thromb Res. 2003;112(4):223-7 14987915 J Neurol Sci. 1998 Oct 8;160(2):158-60 9849798 J Am Coll Cardiol. 1996 Sep;28(3):768-72 8772770 Circulation. 1993 Jun;87(6):1954-9 8504509

2006 Heart

4429. Echocardiography in adult congenital heart disease Full Text available with Trip Pro

Echocardiography in adult congenital heart disease 10078071 1999 03 18 2018 11 13 1355-6037 80 Suppl 1 1998 Nov Heart (British Cardiac Society) Heart Echocardiography in adult congenital heart disease. S12-26 Houston A A Department of Cardiology, Royal Hospital for Sick Children, Glasgow, UK. Hillis S S Lilley S S Richens T T Swan L L eng Journal Article Review England Heart 9602087 1355-6037 AIM IM Adult Aortic Coarctation diagnostic imaging Cor Triatriatum diagnostic imaging Echocardiography (...) Echocardiography, Doppler, Color Echocardiography, Transesophageal Heart Defects, Congenital diagnostic imaging Heart Septal Defects diagnostic imaging Humans Pulmonary Atresia diagnostic imaging Tetralogy of Fallot diagnostic imaging Transposition of Great Vessels diagnostic imaging Truncus Arteriosus, Persistent diagnostic imaging 87 1999 3 17 1999 3 17 0 1 1999 3 17 0 0 ppublish 10078071 PMC1766496 Circulation. 1984 Nov;70(5):898-902 6488503 Br Heart J. 1982 Apr;47(4):316-28 7066116 J Am Coll Cardiol. 1985

1998 Heart

4430. Transoesophageal echocardiography in adult congenital heart disease Full Text available with Trip Pro

Transoesophageal echocardiography in adult congenital heart disease 11709532 2001 12 14 2018 11 13 1468-201X 86 Suppl 2 2001 Dec Heart (British Cardiac Society) Heart Transoesophageal echocardiography in adult congenital heart disease. II30-II40 Masani N D ND Department of Cardiology, University Hospital of Wales, Heath Park, Cardiff CF14 4XW. navroz.masani@cardiffandvale.wales.nhs.uk eng Journal Article Review England Heart 9602087 1355-6037 AIM IM Adult Echocardiography, Doppler, Color (...) methods Echocardiography, Transesophageal methods Heart Atria diagnostic imaging Heart Defects, Congenital diagnostic imaging Heart Septal Defects, Atrial diagnostic imaging Heart Septal Defects, Ventricular diagnostic imaging Humans Pulmonary Veins abnormalities diagnostic imaging Transposition of Great Vessels diagnostic imaging surgery 5 2001 11 16 10 0 2002 1 5 10 1 2001 11 16 10 0 ppublish 11709532 PMC1766552 Heart. 2001 Apr;85(4):438-43 11250973 Br Heart J. 1979 May;41(5):544-53 465224 Heart

2001 Heart

4431. Congenital heart disease in adults. Full Text available with Trip Pro

electrocardiogram, chest x-ray film, and echocardiography, are often sufficient to establish a diagnosis and to assess the adequacy of a previous operation. Transesophageal echocardiography and magnetic resonance imaging are adjunctive procedures that are indicated when routine transthoracic echocardiography is limited. Cardiac catheterization may be necessary when the noninvasive data are ambiguous and to assess coronary artery disease (congenital and acquired) in patients considered for surgical therapy (...) Congenital heart disease in adults. Patients reaching adulthood with unoperated and operated congenital heart disease require attention to issues of exercise, antibiotic prophylaxis, contraception, and pregnancy. A careful clinical history is important to establish the degree of a person's disability, if any, and the symptoms responsible for the disability, whether due to heart failure, cyanosis, or both. The findings of a physical examination and a noninvasive evaluation, including

1995 Western Journal of Medicine

4432. ECG determinants in adult patients with chronic right ventricular pressure overload caused by congenital heart disease: relation with plasma neurohormones and MRI parameters. Full Text available with Trip Pro

ECG determinants in adult patients with chronic right ventricular pressure overload caused by congenital heart disease: relation with plasma neurohormones and MRI parameters. To examine retrospectively the changes in ECG parameters over time and their correlation with other quantitative right ventricular (RV) function parameters in patients with chronic RV pressure overload caused by congenital heart disease.48 patients with chronic RV pressure overload caused by the following congenital heart (...) diseases were studied: nine with congenitally corrected transposition of the great arteries (TGA), 12 with surgically corrected TGA, and 27 with a subpulmonary pressure overloaded RV. QRS duration and dispersion were measured manually from standard ECG recorded twice within five years. RV end diastolic volume (EDV) and RV mass were determined by magnetic resonance imaging. Brain natriuretic peptide (BNP) plasma concentrations were measured.QRS duration and QRS dispersion increased in all patient groups

2002 Heart

4433. MR Imaging of Congenital Heart Diseases in Adolescents and Adults Full Text available with Trip Pro

MR Imaging of Congenital Heart Diseases in Adolescents and Adults Echocardiography and catheterization angiography suffer certain limitations in the evaluation of congenital heart diseases in adults, though these are overcome by MRI, in which a wide field-of view, unlimited multiplanar imaging capability and three-dimensional contrast-enhanced MR angiography techniques are used. In adults, recently introduced fast imaging techniques provide cardiac MR images of sufficient quality and with less (...) sequelae. Biventricular function is reliably evaluated with cine MRI after repair of tetralogy of Fallot, and Senning's and Mustard's operations. MRI has an important and growing role in the morphologic and functional assessment of congenital heart diseases in adolescents and adults.

2001 Korean Journal of Radiology

4434. Grown-up congenital heart (GUCH) disease: current needs and provision of service for adolescents and adults with congenital heart disease in the UK. Full Text available with Trip Pro

to transplant services familiar with their basic problem, clinical nurse specialist advisors, and trained nurses. An integrated national service is described with 4-6 specialist units established within adult cardiology, ideally in relation or proximity to university hospital/departments in appropriate geographic location, based in association with established paediatric cardiac surgical centres with designated inpatient and outpatient facilities for grown-up patients with congenital heart disease (...) Grown-up congenital heart (GUCH) disease: current needs and provision of service for adolescents and adults with congenital heart disease in the UK. This report addresses the needs and problems of grown-up congenital heart (GUCH) patients and makes recommendations on organisation of national medical care, training of specialists, and education of the profession. The size of the national population of patients with grown-up congenital heart disease (GUCH) is uncertain, but since 80-85

2002 Heart

4435. Imaging the heart in adult congenital heart disease Full Text available with Trip Pro

Imaging the heart in adult congenital heart disease 10065017 1999 03 09 2008 11 20 1355-6037 80 6 1998 Dec Heart (British Cardiac Society) Heart Imaging the heart in adult congenital heart disease. 535-6 Stumper O O eng Editorial England Heart 9602087 1355-6037 AIM IM Adult Coronary Angiography Echocardiography Heart Defects, Congenital diagnosis surgery Humans Magnetic Resonance Imaging Myocardium pathology Patient Selection 1999 3 5 1999 3 5 0 1 1999 3 5 0 0 ppublish 10065017 PMC1728878

1998 Heart

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