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Congenital Heart Disease Imaging in Adults

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21. White Matter Hyperintensities Burden in Adult Patients With Cyanotic Congenital Heart Disease: a Pilot Study

White Matter Hyperintensities Burden in Adult Patients With Cyanotic Congenital Heart Disease: a Pilot Study White Matter Hyperintensities Burden in Adult Patients With Cyanotic Congenital Heart Disease: a Pilot Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (...) (100). Please remove one or more studies before adding more. White Matter Hyperintensities Burden in Adult Patients With Cyanotic Congenital Heart Disease: a Pilot Study The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier

2018 Clinical Trials

22. Transplantation and Mechanical Circulatory Support in Congenital Heart Disease

mortality across ACHD diagnosis ACHD indicates adult congenital heart disease; BNP, brain natriuretic peptide; CHD, congenital heart disease; d-TGA, dextro transposition of the great arteries; ES, Eisenmenger syndrome; HF, heart failure; LV, left ventricular; MRI, magnetic resonance imaging; NT-pro-BNP, N-terminal pro-brain natriuretic peptide; peak , peak oxygen consumption; PH, pulmonary hypertension; RA, right atrial; RV, right ventricular; TGA, transposition of the great arteries; TOF, tetralogy (...) are agreeing to our use of cookies. Free Access article Share on Jump to Free Access article Transplantation and Mechanical Circulatory Support in Congenital Heart Disease A Scientific Statement From the American Heart Association , MD, MHSc, Chair , MD, Vice Chair , MD , MD , MD , MD , MD , MD, MSc , MD, MSc , MD , MD, PhD , MBChB , MD, FAHA , MD, FAHA , MD , MD, FAHA , MD , and MD, FAHA MDon behalf of the American Heart Association Adults With Congenital Heart Disease Committee of the Council on Clinical

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2016 American Heart Association

23. The Boston Circulatory Arrest Study: Antecedents and Correlates of Well-Being in Adults With Congenital Heart Disease

The Boston Circulatory Arrest Study: Antecedents and Correlates of Well-Being in Adults With Congenital Heart Disease The Boston Circulatory Arrest Study: Antecedents and Correlates of Well-Being in Adults With Congenital Heart Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. The Boston Circulatory Arrest Study: Antecedents and Correlates of Well-Being in Adults With Congenital Heart Disease (BCAS-Adult) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details

2017 Clinical Trials

24. Three-dimensional echocardiography in adult congenital heart disease (PubMed)

Three-dimensional echocardiography in adult congenital heart disease Congenital heart disease (CHD) is now more common in adults than in children due to improvements in fetal echo, neonatal and pediatric care, and surgical techniques leading to dramatically increased survivability into adulthood. Adult patients with CHD, regardless of prior cardiac surgery, experience further cardiac problems or therapeutic challenges; therefore, a non-invasive, easily accessible echocardiographic examination (...) . In repaired tetralogy of fallot with pulmonary regurgitation, preoperative 3D echocardiography- based right ventricular volume may be used to determine the timing of a pulmonary valve replacement in conjunction with cardiovascular magnetic imaging. For optimal adult CHD care, 3D echocardiography is an important complement to routine 2D echocardiography.

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2017 The Korean journal of internal medicine

25. Exposure to Low-Dose Ionizing Radiation from Cardiac Procedures and Malignancy Risk in Adults with Congenital Heart Disease. (PubMed)

Exposure to Low-Dose Ionizing Radiation from Cardiac Procedures and Malignancy Risk in Adults with Congenital Heart Disease. Adults with congenital heart disease (CHD) are exposed to increasing amounts of low-dose ionizing radiation (LDIR) from cardiac procedures. Cancer prevalence in this population is higher than in the general population. This study estimates the association between LDIR exposure from cardiac procedures and incident cancer in adult patients with CHD.The study population (...) derived from the Quebec Congenital Heart Disease Database. We measured cumulative numbers of LDIR-related cardiac procedures for each patient until 1 year before the time of cancer diagnosis or administrative censoring. To assess the association between LDIR exposure and cancer risk, we conducted a nested case-control study and matched cancer cases with controls on sex, CHD severity, birth year, and age.The study included 24 833 adult patients with CHD aged 18 to 64 years from 1995 to 2009. In >250

2017 Circulation

26. Chronic heart failure in adults: diagnosis and management

heart failure 27 4 The impact of advanced kidney disease on the natriuretic peptide threshold for diagnosing heart failure 27 5 Risk tools for predicting non-sudden death in heart failure 28 Update information 29 Chronic heart failure in adults: diagnosis and management (NG106) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 3 of 37September 2018 29 Recommendations that have been changed 29 Chronic heart failure (...) transthoracic echocardiography to exclude important valve disease, assess the systolic (and diastolic) function of the (left) ventricle, and detect intracardiac shunts. [2003, amended 2018] [2003, amended 2018] 1.2.9 Transthoracic echocardiography should be performed on high-resolution Chronic heart failure in adults: diagnosis and management (NG106) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 9 of 37equipment

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

27. Three-Dimensional Rotational Angiography in Pediatric Patients with Congenital Heart Disease: A Literature Review. (PubMed)

Three-Dimensional Rotational Angiography in Pediatric Patients with Congenital Heart Disease: A Literature Review. Cardiac catheterization is a commonly used form of imaging and treatment in pediatric patients with congenital heart disease. Traditionally, two-dimensional conventional angiography was the method used, but since 2000 three-dimensional rotational angiography (3DRA) is increasingly used in the field of cardiology in both adult and pediatric patients. To investigate the use (...) and applications of 3DRA in pediatric congenital cardiology, literature was systematically reviewed and 29 eligible articles were found. Those showed that 3DRA is already a greatly valued diagnostic and therapeutic technique in pediatric cardiology. However, the literature misses well-designed clinical, homogeneous, multicenter, prospective studies recording data in a standardized manner. These studies are necessary to ensure proper data analysis and to investigate the true advantages of 3DRA and how

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2019 Pediatric Cardiology

28. Right ventricular failure in congenital heart disease. (PubMed)

Right ventricular failure in congenital heart disease. We aim to review select literature pertaining to congenital heart disease (CHD)-induced right ventricular (RV) function and failure.We review recent findings pertaining to children and adults with repaired tetralogy of Fallot (rTOF), systemic RV and hypoplastic left heart syndrome (HLHS). We emphasize pathophysiological mechanisms contributing to RV dysfunction in these conditions, the risk factors for adverse outcomes and the continuing (...) challenges in treating these patients. We discuss how recent pathology findings, as well as developments in imaging and computer modeling have broadened our understanding of the pathophysiology of these conditions. We further review developments in the molecular and cellular basis of RV failure; and in particular, the RV molecular response to stress in repaired tetralogy of Fallot (rTOF). We highlight some of the genetic complexities in HLHS and how these may influence the long-term outcomes

2019 Current opinion in pediatrics

29. Multimodality imaging in congenital heart disease-related pulmonary arterial hypertension. (PubMed)

Multimodality imaging in congenital heart disease-related pulmonary arterial hypertension. Pulmonary arterial hypertension (PAH) in adult patients with congenital heart disease (CHD) is associated with increased morbidity and mortality. The present review aims to discuss the clinical applications of invasive and non-invasive diagnostic modalities and to describe the strengths and weaknesses of each technique. Chest radiograph is an inexpensive investigation providing information on pulmonary (...) and pulmonary circulation, may represent an ideal target for evaluation with cardiac magnetic resonance. This non-invasive imaging modality has a low biological impact. CT plays an important role for patients with limited echocardiographic windows and those who are unable to undergo MRI (claustrophobia, poor compliance, presence of a pacemaker/implantable cardioverter defibrillator). It is the modality of choice for detailed assessment of pulmonary vessel obstruction or thrombosis. Finally, heart

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2016 Heart

30. Aquilion PRIME CT scanner for imaging coronary artery disease in adults in whom imaging is difficult

, AI M, Burgers L et al. (2013) A systematic review and economic evaluation of new- generation computed tomography scanners for imaging in coronary artery disease and congenital heart disease: Somatom Definition Flash, Aquilion ONE, Brilliance iCT and Discovery CT750 HD. Health T echnology Assessment 17: 1-243 Aquilion PRIME CT scanner for imaging coronary artery disease in adults in whom imaging is difficult (MIB53) © NICE 2018. All rights reserved. Subject to Notice of rights (https (...) people with obesity, high levels of coronary calcium, arrhythmias, high heart rates, stents or bypass grafts. It can also be used for other clinical imaging applications in adults and children. Effectiv Effectiveness and safety eness and safety There is no published evidence on the safety or effectiveness of the Aquilion PRIME scanner in people with difficult-to-image coronary artery disease. There is little evidence available on many CT scanner models in difficult-to-image subgroups because

2016 National Institute for Health and Clinical Excellence - Advice

31. Somatom Definition Edge CT scanner for imaging coronary artery disease in adults in whom imaging is difficult

with earlier generation CT is difficult. This includes people with obesity, high levels of coronary calcium, arrhythmias, high heart rates, stents or bypass grafts. It can also be used for other clinical imaging applications in adults and children. Effectiv Effectiveness and safety eness and safety There is no published evidence on the safety or effectiveness of the Somatom Definition Edge scanner in people with difficult-to-image coronary artery disease. There is little evidence available on many CT (...) computed tomography scanners for imaging in coronary artery disease and congenital heart disease: Somatom Definition Flash, Aquilion ONE, Brilliance iCT and Discovery CT750 HD. Health T echnology Assessment 17: 1–243 Appendix Appendix Search strategy and evidence selection Search str Search strategy ategy F For the clinical e or the clinical evidence vidence Embase 1980 to 2015 October 22, Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) 1946 to Present; searched 22 October

2016 National Institute for Health and Clinical Excellence - Advice

32. Myocardial Perfusion and Scarring in Adults With Congenital Heart Disease

Myocardial Perfusion and Scarring in Adults With Congenital Heart Disease Myocardial Perfusion and Scarring in Adults With Congenital Heart Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Myocardial (...) Perfusion and Scarring in Adults With Congenital Heart Disease The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02861365 Recruitment Status : Active, not recruiting First Posted : August 10, 2016 Last Update Posted : January 30, 2019 Sponsor: Children's Research Institute Collaborator: National Institutes

2016 Clinical Trials

33. Feasibility of low radiation dose retrospectively-gated cardiac CT for functional analysis in adult congenital heart disease. (PubMed)

Feasibility of low radiation dose retrospectively-gated cardiac CT for functional analysis in adult congenital heart disease. The use of cardiac computed tomography (CT) in the evaluation of adult congenital heart disease patients is limited due to concerns of high radiation doses. The purpose of this study was to prospectively assess whether low radiation dose cardiac CT is feasible to evaluate ventricular systolic function in adults with congenital heart disease.The study group included 30 (...) cardiac CT with a median radiation dose of less than 1mSv was successful in evaluating ventricular systolic function in 30 consecutive adult congenital heart disease patients who underwent a total of 35 scans.Published by Elsevier Ireland Ltd.

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2016 International journal of cardiology

34. AIM Clinical Appropriateness Guidelines for Advanced Imaging of the Heart.

2019. AIM Specialty Health. All Rights Reserved. 7 Imaging Considerations Myocardial Perfusion Imaging and Stress Echocardiography may provide useful information on Coronary Heart Disease. Comparison data on Sensitivity and Specificity are provided in Table 2 below. Due to regional variation in technical expertise and interpretive proficiency, the clinician should use the diagnostic imaging modality that has been proven most accurate in his/her practices. Table 2: Comparison of Non-Invasive (...) in morbidly obese patients (BMI >40) is usually suboptimal such that consideration should be given to other imaging modalities. If imaging studies using other radioactive tracers have been recently performed, adequate time must elapse to allow for clearance of activity from the heart and surrounding regions. ? For patients who are unable to walk on a treadmill for non-cardiac reasons (orthopedic limitations, claudication, neurological conditions, advanced lung disease, etc.), exercise stress testing

2019 AIM Specialty Health

35. 2017 AHA/ACC Key Data Elements and Definitions for Ambulatory Electronic Health Records in Pediatric and Congenital Cardiology: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards

to occur. The other domains include: congenital heart defect nomenclature, adult congenital heart disease, critical care, cardiomyopathy, cardiac transplantation, pulmonary hypertension, congenital cardiac surgery, echocardiography, diagnostic and interventional catheterization, exercise stress testing and physiology, electrophysiology, cardiac magnetic resonance imaging, fetal physiology, perfusion, and cardiac anesthesia. The reason that this domain was chosen first was that there are other nascent (...) guidelines, and determine statistical significance in our patient populations. There is a wide range of disease processes across a relatively small set of patients in pediatric and congenital heart disease; this fact is in contrast to adult cardiac disease where there is a large population of patients who experience a more homogenous set of disease processes. In a year, a cardiac center in adult medicine is likely to treat thousands of patients who present with one of only a few disease processes. Adult

2017 American Heart Association

36. Integrated Computational modelIng of Right Heart Mechanics and Blood Flow Dynamics in Congenital Heart Disease

. The improvement in survival of CHD patients has led to burgeoning numbers of grown-up CHD.The majority of these CHD patients face a lifetime of problems including RV dilation, ventricular arrhythmias, and sudden cardiac death.Considering inflation to visit costs and added image technology for diagnosis, the cost of each patient is expected to increase .In contrast to adult patients with acquired heart disease, abnormalities of the RV are ubiquitous in children and adults with CHD. Currently, clinical (...) Integrated Computational modelIng of Right Heart Mechanics and Blood Flow Dynamics in Congenital Heart Disease Integrated Computational modelIng of Right Heart Mechanics and Blood Flow Dynamics in Congenital Heart Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved

2017 Clinical Trials

37. Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 4: Congenital Heart Disease

of this article. Previous versions: Introduction Congenital heart disease (CHD) is the most common form of serious birth defect, occurring in 8 per 1000 live births. The past several decades have seen dramatic improvements in survival with palliative or corrective heart surgery, such that there are now more adult patients than pediatric patients alive with CHD. Although restriction from competitive athletics may well be indicated for some, the great majority of patients can and should engage in some form (...) Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 4: Congenital Heart Disease Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 4: Congenital Heart Disease | Circulation Search Hello Guest! Login to your account Email Password Keep me logged in Search March 2019 March 2019 March 2019 March 2019 March 2019 February 2019 February 2019 February 2019 February

2015 American Heart Association

38. Current Interventional and Surgical Management of Congenital Heart Disease: Specific Focus on Valvular Disease and Cardiac Arrhythmias. (PubMed)

Current Interventional and Surgical Management of Congenital Heart Disease: Specific Focus on Valvular Disease and Cardiac Arrhythmias. Successful outcome in the care of patients with congenital heart disease depends on a comprehensive multidisciplinary team. Surgery is offered for almost every heart defect, despite complexity. Early mortality for cardiac surgery in the neonatal period is ≈10% and beyond infancy is <5%, with 90% to 95% of patients surviving with a good quality of life (...) into the adult years. Advances in imaging have facilitated accurate diagnosis and planning of interventions and surgical procedures. Similarly, advances in the perioperative medical management of patients, particularly with intensive care, has also contributed to improving outcomes. Arrhythmias and heart failure are the most common late complications for the majority of defects, and reoperation for valvar problems is common. Lifelong surveillance for monitoring of recurrent or residual structural heart

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2017 Circulation Research

39. Imaging of congenital heart disease in adults. (PubMed)

Imaging of congenital heart disease in adults. Imaging is fundamental to the lifelong care of adult congenital heart disease (ACHD) patients. Echocardiography remains the first line imaging for inpatient, outpatient, or perioperative care. Cross-sectional imaging with cardiovascular magnetic resonance (CMR) or computed tomography (CT) provides complementary and invaluable information on cardiac and vascular anatomy and other intra-thoracic structures. Furthermore, CMR provides quantification (...) of cardiac function and vascular flow. Cardiac catheterization is mostly reserved for assessment of pulmonary vascular resistance, ventricular end-diastolic pressure, and percutaneous interventions. There have been further advances in non-invasive imaging for ACHD including the application of advanced echocardiographic techniques, faster automated CMR imaging, and radiation dose reduction in CT. As a result ACHD, a heterogeneous population, benefit from appropriate application of multiple imaging

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2015 European heart journal

40. Hypothyroidism With Congenital Heart Disease (CHD)

. According to the Italian Registry of Congenital Hypothyroidism, congenital heart disease is the most frequent disease condition associated with congenital hypothyroidism. Congenital heart disease is also reported to be a risk factor for non-autoimmune hypothyroidism in children. In addition, intravenous iodine contrast media is frequently used for diagnostic imaging and therapeutic intervention in congenital heart disease patients. Excess iodine exposed by iodine contrast media may disturb thyroid (...) function in adult and pediatric population. However, there is no generally accepted guideline for screening thyroid dysfunction in congenital heart disease infants. An increased prevalence of thyroid disease, particularly sub-clinical hypothyroidism, has been reported in Down Syndrome. In children with Down Syndrome, a possible concomitant sub-clinical hypothyroidism-related impairment of cardiac function or structure may worsen their clinical condition and can ultimately affect their life expectancy

2018 Clinical Trials

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